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1

Bion, Julian, A. Alperovitch, J. R. Le Gall, and P. Loirat. "PREDICTION BY APACHE SCORE." Lancet 328, no. 8501 (1986): 286–87. http://dx.doi.org/10.1016/s0140-6736(86)92106-9.

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Polita, Jorge Roberto, Jussara Gomez, Gilberto Friedman, and Sérgio Pinto Ribeiro. "Comparison of APACHE II and three abbreviated APACHE II scores for predicting outcome among emergency trauma patients." Revista da Associação Médica Brasileira 60, no. 4 (2014): 381–86. http://dx.doi.org/10.1590/1806-9282.60.04.018.

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Objective: to compare the ability of the APACHE II score and three different abbreviated APACHE II scores: simplified APACHE II (s-APACHE II), Rapid Acute Physiology score (RAPS) and Rapid Emergency Medicine score to evaluate in-hospital mortality of trauma patients at the emergency department (ED). Methods: retrospective analysis of a prospective cohort study. All patients' victims of trauma admitted to the ED, during a 5 months period. For all entries to the ED, APACHE II score was calculated. APACHE II system was abbreviated by excluding the laboratory data to calculate s-APACHE II score fo
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Rathod, Nikhil, and Archana Deshpande. "Comparative Study of Glasgow Coma Score, Poisoning Severity Score and APACHE 2 Score in Predicting Outcome of the Patients with Organophosphate Poisoning." Vidarbha Journal of Internal Medicine 32 (January 31, 2022): 29–34. http://dx.doi.org/10.25259/vjim_3_2021.

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Objectives: This study aims to calculate and compare Glasgow Coma Score, International Program on Chemical Safety Poisoning Severity Score and Acute Physiology and Chronic Health Evaluation 2 score in predicting outcome of the patients with organophosphate compound poisoning. Material and Methods: A total of 100 patients were taken in the study from December 2018 to December 2020. Glasgow Coma Score (GCS), International Program on Chemical Safety Poisoning Severity Score (IPCS PSS) and Acute Physiology and Chronic Health Evaluation 2 (APACHE 2) score of each patient were calculated and compare
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Muhammad Mufti Sofyanoor, Yunita Widyastuti, Juni Kurniawaty, and Djayanti Sari. "Validity of Acute Physiology and Chronic Health Evaluation (APACHE) IV for the Prediction of Prolonged Intensive Care Unit (ICU) Length of Stay in Dr. Sardjito General Hospital in the COVID Era." Journal of Anesthesiology and Clinical Research 4, no. 2 (2023): 426–33. http://dx.doi.org/10.37275/jacr.v4i2.302.

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Introduction: APACHE IV was a good predictor of ICU length of stay in the USA and some countries outside the USA but poor in others. It is important to develop a scoring system for the Indonesian population, especially in this scope, Dr. Sardjito General Hospital. To develop such a scoring system, it is reasonable to study the validity of APACHE IV in ICU Dr. Sardjito General Hospital for predicting prolonged length of stay.
 Methods: A retrospective cohort observational study using data from January 1st, 2020, to December 31st, 2020, taken from the ICU of Dr. Sardjito General Hospital. T
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Manas, Ranjan Behera. "Apache II Score Evaluation of Routine Ilesostomy Results in Ileal Perforation." International Journal of Pharmaceutical and Clinical Research 15, no. 6 (2023): 309–14. https://doi.org/10.5281/zenodo.12154479.

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<strong>Objective:&nbsp;</strong>Ileal perforation peritonitis is a common surgical emergency in the Indian subcontinent and in tropical countries. It is reported to constitute the fifth most common cause of abdominal emergencies due to high incidence of enteric fever and tuberculosis in these management based on Acute Physiological and Chronic Health Evaluation II (APACHE II) score.&nbsp;<strong>Method:&nbsp;</strong>This study was conducted in the 60 patients, who were admitted from causality and surgical outpatient department with a proven diagnosis of ileal perforation peritonitis. The pat
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Chang, R. W. S. "APACHE II and clinical sickness score." Anaesthesia 46, no. 11 (1991): 988–89. http://dx.doi.org/10.1111/j.1365-2044.1991.tb09874.x.

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Bohnen, John M. A. "APACHE II Score and Abdominal Sepsis." Archives of Surgery 123, no. 2 (1988): 225. http://dx.doi.org/10.1001/archsurg.1988.01400260113014.

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SCHEIN, MOSHE. "APACHE II Score in Abdominal Sepsis." Archives of Surgery 123, no. 10 (1988): 1288. http://dx.doi.org/10.1001/archsurg.1988.01400340114026.

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Ibtisam Ahmed Khan, Muhammad Kareem Ullah, Saeed Mahmood, Adnan Sadiq Butt, Naeem Sarwar, and Bilal Afsar. "Predictive accuracy of APACHE II score in predicting mortality in poly Trauma patients." Professional Medical Journal 28, no. 12 (2021): 1752–57. http://dx.doi.org/10.29309/tpmj/2021.28.12.6852.

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Objective: To find diagnostic precision of APACHE II score in predicting mortality in poly Trauma patients within first 24 hours of hospitalization. Study Design: Cross Sectional study. Setting: Emergency Department of Lahore General Hospital. Period: 2018-2019. Materials &amp; Methods: A total of 270 patients who fulfilled selection criteria were enrolled in the study. To calculate APACHE II score, age, vitals, CBC level, Glasgow coma scale score and chronic health points were measured. Patients were classified as per their APACHE II score. After calculating APACHE II score patients were mana
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Bezmarevic, Mihailo, Zoran Kostic, Miodrag Jovanovic, et al. "Procalcitonin and BISAP score versus c-reactive protein and APACHE II score in early assessment of severity and outcome of acute pancreatitis." Vojnosanitetski pregled 69, no. 5 (2012): 425–31. http://dx.doi.org/10.2298/vsp1205425b.

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Background/Aim. Early assessment of severity and continuous monitoring of patients are the key factors for adequate treatment of acute pancreatitis (AP). The aim of this study was to determine the value of procalcitonin (PCT) and Bedside Index for Severity in Acute Pancreatitis (BISAP) scoring system as prognostic markers in early stages of AP with comparison to other established indicators such as Creactive protein (CRP) and Acute Physiology and Chronic Health Evaluation (APACHE) II score. Methods. This prospective study included 51 patients (29 with severe AP). In the first 24 h of admission
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Wang, Chang-yong, Min Shang, Li-zhi Feng, Chen-liang Zhou, Qing-shan Zhou, and Ke Hu. "Correlation between APACHE III score and sleep quality in ICU patients." Journal of International Medical Research 47, no. 8 (2019): 3670–80. http://dx.doi.org/10.1177/0300060519856745.

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Objective To reveal the correlation between APACHE III score and sleep quality in patients in the intensive care unit (ICU). Methods This prospective, observational study included patients aged ≥18 years, who had been admitted to an integrated ICU for ≥48 h. Age, sex, Pittsburgh Sleep Quality Index (PSQI) prior to ICU, Numeric Rating Scales (NRS), noise, illumination, number of nursing interventions, Richards Campbell Sleep Questionnaire (RCSQ), and APACHE III score during sleep were evaluated. Results A total of 124 ICU patients were included, all with APACHE III scores &lt; 60. APACHE III sc
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Kahraman, Fatih, Ahmet Seyda Yılmaz, Mevlüt Demir, and Fatih Beşiroğlu. "APACHE II score predicts in-hospital mortality more accurately than inflammatory indices in patients with acute coronary syndrome." Kardiologiia 62, no. 9 (2022): 54–59. http://dx.doi.org/10.18087/cardio.2022.9.n1979.

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Aim This study evaluated the prognostic ability of the APACHE II score and compared it with inflammatory indices in patients with acute coronary syndrome (ACS).Material and Methods A total of 525 patients with ACS were retrospectively enrolled in the study. APACHE II scores were calculated and C-reactive protein (CRP), neutrophil-lymphocyte ratio (NLR), and systemic immune-inflammatory index (SII) were recorded. The APACHE II score was compared with inflammatory indices for predicting in-hospital mortality.Results Univariate logistic regression (LR) analysis showed that CRP, SII, NLR, ejection
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Punyapu, Sridhar, Karthik Thota, Balakrishna Ganga, Sravanthi Kanumuri, Zainab Farooqi, and Nikhil Mehra Panguluru A S. "Assessment of severity of peritonitis due to hollow viscous perforation- using APACHE II score." Panacea Journal of Medical Sciences 13, no. 1 (2023): 181–87. http://dx.doi.org/10.18231/j.pjms.2023.037.

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: Acute widespread peritonitis caused by a perforated hollow viscus is a potentially fatal illness. It's a common surgical emergency in many developing-country general surgical departments, and it's often associated with substantial morbidity and mortality. Grading the severity of acute peritonitis has greatly aided decision-making and improved the therapeutic success in the management of critically ill patients. Empirically based risk assessment for major clinical events has proven to be tremendously valuable in evaluating new medicines, monitoring resource utilisation, and improving care qua
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Qiao, Q., G. Lu, M. Li, Y. Shen, and D. Xu. "Prediction of Outcome in Critically Ill Elderly Patients using APACHE II and SOFA Scores." Journal of International Medical Research 40, no. 3 (2012): 1114–21. http://dx.doi.org/10.1177/147323001204000331.

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OBJECTIVE: Performances of the Acute Physiology and Chronic Health Evaluation II (APACHE II) score and the Sequential Organ Failure Assessment (SOFA) score were assessed in predicting mortality outcome in critically ill elderly patients. METHODS: Mean APACHE II and SOFA scores were compared in 106 intensive care unit patients aged &gt; 65 years classified as survivors or deaths. The discriminatory ability of the scores was evaluated using the area under the receiver operating characteristic (ROC) curve. Calibration was assessed using the Hosmer—Lemeshow test. RESULTS: Mean APACHE II and SOFA s
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Majmundar, Aarjuv, Prayans Shah, Jayant Mayavanshi, et al. "Sequential APACHE II Scores for Prediction of Mortality in Patients with Severe Malaria and Admitted to Critical Care Facilities." International Journal of TROPICAL DISEASE & Health 44, no. 7 (2023): 15–22. http://dx.doi.org/10.9734/ijtdh/2023/v44i71418.

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Background/Aims: Both generic and disease specific prognostic scoring systems have been employed in areas of critical care. The score of Acute Physiology and Chronic Health Evaluation (APACHE) II is a generic point score which provides general assessment of illness and severity. In order to determine the mortality of critically ill malaria patients, this study aims to find the ideal time point for the APACHE II score.&#x0D; Materials and Methods: This longitudinal study was carried out after getting necessary ethics committee approval. Score of APACHE II on days 0, 2nd and 7th were evaluated a
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Kumar, Pawanjeet, Kundan Singh, and Amarnath Kumar. "A comparative study between Mannheim peritonitis index and APACHE II in predicting the outcome in patients of peritonitis due to hollow viscous perforation." International Surgery Journal 4, no. 2 (2017): 690. http://dx.doi.org/10.18203/2349-2902.isj20170215.

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Background: The identification and early assessment of peritonitis patient is often required in surgical emergency to select the high risk patients for intensive management for better outcome. This is a comparative study of efficacy between Mannheim peritonitis index and APACHE II in predicting the outcome in patients of peritonitis due to hollow viscous perforation.Methods: Comparative and prospective study in 50 patients of hollow viscous perforation admitted and operated in surgical emergency, Patna Medical College and Hospital from year April 2014 to April 2016 was done. Mannheim peritonit
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Ho, K. M. "Combining Sequential Organ Failure Assessment (SOFA) Score with Acute Physiology and Chronic Health Evaluation (APACHE) II Score to Predict Hospital Mortality of Critically Ill Patients." Anaesthesia and Intensive Care 35, no. 4 (2007): 515–21. http://dx.doi.org/10.1177/0310057x0703500409.

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The ability to accurately adjust for the severity of illness in outcome studies of critically ill patients is essential. Previous studies have showed that Sequential Organ Failure Assessment (SOFA) score and Acute Physiology and Chronic Health Evaluation (APACHE) II score can predict hospital mortality of critically ill patients. The effects of combining these two scores to predict hospital mortality of critically ill patients has not been evaluated. This cohort study evaluated the performance of combining the APACHE II score with SOFA score in predicting hospital mortality of critically ill p
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Yusuf, Muhammad, Nurhayat Usman, Reno Rudiman, and Muhammad Bayu Z. Hutagalung. "Evaluation of acute physiology and chronic health evaluation IV predictive scoring as mortality predictor among individual with cholangitis." International Journal of Research in Medical Sciences 6, no. 12 (2018): 3920. http://dx.doi.org/10.18203/2320-6012.ijrms20184883.

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Background: Evaluation of the effectiveness of care and clinical outcomes in critically ill patients is dependent on predictive scoring models that calculate measures of disease severity and mortality. Cholangitis is an infection and obstruction of the biliary system. The APACHE IV scoring system is a logistic regression model incorporating physiologic and laboratory parameters. APACHE IV is the most updated scoring system for Intensive Care Unit (ICU) mortality prediction.Methods: A cohort study with 65 cholangitis patient that fulfilled diagnostic criteria of Tokyo guideline 2013 was include
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Aroor, Akshatha Rao, Archana Bhat, and Maroli Roshan. "Correlation of thyroid hormone profile and acute physiology and chronic health evaluation II (APACHE II) score with the survival in sepsis in a tertiary care centre." Asian Journal of Medical Sciences 12, no. 2 (2021): 19–24. http://dx.doi.org/10.3126/ajms.v12i2.31789.

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Background: Thyroid hormone plays a pivotal role in the adaptation of metabolic function to stress and critical illness like sepsis. Thyroid dysfunction is associated with increased mortality in sepsis. The role of thyroid dysfunction as a prognostic marker in sepsis remains unclear.&#x0D; Aims and Objectives: To correlate the baseline thyroid function tests with APACHE II score and mortality in adult patients admitted with sepsis in Intensive Care Unit (ICU).&#x0D; Materials and Methods: This was a cross sectional, observational study done for a period of one year from September 2019 to Septe
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Vijaykumar C Bada and K Ravindranath. "Evaluation of Ranson’s Score, Glasgow, Apache II, Apache O, Balthazar CTSI in Acute Pancreatitis Patients." Academia Journal of Surgery 3, no. 1 (2020): 132–35. http://dx.doi.org/10.47008/ajs/2020.3.1.29.

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Background: Pancreatitis is an inflammation of the glandular parenchyma leading to injury or destruction of acinar components. This study was conducted to evaluate Ranson’s score, Glasgow, APACHE II, APACHE O, Balthazar CTSI in acute pancreatitis patients. Subjects and Methods: This study was conducted at Department of surgical Gastroenterology, Global hospital Hyderabad to evaluate Ranson’s score, Glasgow, APACHE II, APACHE O, Balthazar CTSI in acute pancreatitis patients. Results: 34% of the patients in the study were aged 31-40 years and only 6% of the patients were aged &gt;60 years. The e
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Hadisiswoyo, Pauline, Endang Retnowati, and Erwin Astha Triyono. "CORRELATION BETWEEN LEVEL OF SOLUBLE FAS AND DEGREE OF SEPSIS SEVERITY BASED ON APACHE II SCORE." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 24, no. 3 (2018): 231. http://dx.doi.org/10.24293/ijcpml.v24i3.1402.

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A widely used scoring system to assess the severity of sepsis is Acute Physiology, Age, and Chronic Health Evaluation (APACHE) II scoring system, however there are some disadvantages in using this. Other parameters are needed to predict severity and outcome of sepsis. Proinflammatory cytokines and Fas receptors are increased in sepsis and their concentration elevations are correlated with disease severity. An increase of soluble Fas level will follow increasing Fas receptors. This study aimed to prove any correlation between the level of soluble Fas and degree of sepsis severity based on APACH
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Ali, Ahmad, Sabariah Harun, Noordin Othman, et al. "Discriminatory Performance of APACHE II Score and the Prediction of Mortality within the ICU in Patients with Sepsis Admitted to the ICU." Materia Socio Medica 37, no. 2 (2025): 106. https://doi.org/10.5455/msm.2025.37.

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Background: Severity of illness assessment tools are utilized to triage critically-ill patients and provide a valuable inputs to the healthcare provider to decide the type and intensity of treatment or interventions. Objective: The aim of this study was to evaluate the discriminatory capabilities of Acute Physiology And Chronic Health Evaluation II (APACHE II) score in the prediction of Intensive care units (ICUs) mortality among patients with sepsis admitted to the ICU. Methods: Records of patients with sepsis admitted to ICUs were retrospectively reviewed. Discriminatory performance of APACH
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Ali, Ahmad, Sabariah Harun, Noordin Othman, et al. "Discriminatory Performance of APACHE II Score and the Prediction of Mortality within the ICU in Patients with Sepsis Admitted to the ICU." Materia Socio Medica 37, no. 2 (2025): 153. https://doi.org/10.5455/msm.2025.37.153-158.

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Background: Severity of illness assessment tools are utilized to triage critically-ill patients and provide a valuable inputs to the healthcare provider to decide the type and intensity of treatment or interventions. Objective: The aim of this study was to evaluate the discriminatory capabilities of Acute Physiology And Chronic Health Evaluation II (APACHE II) score in the prediction of Intensive care units (ICUs) mortality among patients with sepsis admitted to the ICU. Methods: Records of patients with sepsis admitted to ICUs were retrospectively reviewed. Discriminatory performance of APACH
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Lee, Jun Ho, Seong Youn Hwang, Hye Ran Kim, et al. "Effectiveness of the sequential organ failure assessment, acute physiology and chronic health evaluation II, and simplified acute physiology score II prognostic scoring systems in paraquat-poisoned patients in the intensive care unit." Human & Experimental Toxicology 36, no. 5 (2016): 431–37. http://dx.doi.org/10.1177/0960327116657602.

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Objective: This study was conducted to assess the ability of the sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation (APACHE) II scoring systems, as well as the simplified acute physiology score (SAPS) II method to predict group mortality in intensive care unit (ICU) patients who were poisoned with paraquat. This will assist physicians with risk stratification. Material and methods: The medical records of 244 paraquat-poisoned patients admitted to the ICU from January 2010 to April 2015 were examined retrospectively. The SOFA, APACHE II, and SAPS II sc
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Singh, Rajinder, Harprit Kaur Madan, and Sandeep H. Tayade. "A prospective study of prediction of outcomes in perforative peritonitis using apache II scoring system." International Surgery Journal 4, no. 8 (2017): 2648. http://dx.doi.org/10.18203/2349-2902.isj20173404.

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Background: To predict the risk of mortality and morbidity in patients with perforative peritonitis using APACHE II scoring system. To evaluate the usefulness of APACHE II scoring system as a potential clinical and research tool which could be included as routine part of patient assessment in institution like ours.Methods: This was a prospective, observational study of prediction of outcomes in 80 patients of perforative peritonitis using APACHE II scoring system, conducted during the period of 2 years at our tertiary care institute.Results: Predicted death rate of the study was 17.31% and obs
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Kumar, Sanjana, Jainendra K. Arora, and Sunil Kumar Jain. "Role of acute physiology and chronic health evaluation II scoring system in risk stratification and management of small bowel perforations." International Surgery Journal 7, no. 6 (2020): 1776. http://dx.doi.org/10.18203/2349-2902.isj20202381.

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Background: Despite the surgical treatment, sophisticated intensive care units, latest generation antibiotics and a better understanding of pathophysiology, the morbidity and mortality rate of perforation peritonitis are still high. Patients are usually managed by subjective decision of surgeon based on which mortality is very high.Methods: This was a double-blind observational study conducted over a period of 18 months on 50 patients with small bowel perforations. Based on the acute physiology and chronic health evaluation (APACHE) II score at presentation, patients were triaged into 3 groups
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Kalarickal, Anil, Saumy Johnson, and Anitha Shenoy. "Comparison of Acute Physiology and Chronic Health Evaluation (APACHE) IV and Simplified Acute Physiology Score (SAPS) II in a Tertiary Care Hospital ICU in India." Indian Journal of Respiratory Care 01, no. 02 (2022): 156–60. http://dx.doi.org/10.5005/ijrc-1-1-156.

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Background: APACHE IV and SAPS II are ICU scoring systems used to predict mortality in critically ill patients in the ICU. Aim: To compare mortality prediction using APACHE IV and SAPS II in an Indian ICU. Methods: This prospective study included 225 patients. SAPS II and APACHE IV scoring and predicted mortality were obtained for each patient using online calculators and correlated with actual mortality and length of stay. Results: 183/225 of these admissions were due to medical causes. The mean±SD SAPS II score was 37.97 (±15.85) and APACHE IV score was 64.15 (±20.04). The median SAPS II pre
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Waale, W. H. E., M. Treskes, J. L. P. Duijnhoven, van Puyenbroek, and B. Speelberg. "Colloid osmotic pressure and Apache II score." Intensive Care Medicine 22, S1 (1996): S82. http://dx.doi.org/10.1007/bf01921256.

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Johnson, C. D., S. K. C. Toh, and M. J. Campbell. "Combination of APACHE-II score and an obesity score (APACHE-O) for the prediction of severe acute pancreatitis." Pancreatology 4, no. 1 (2004): 1–6. http://dx.doi.org/10.1159/000077021.

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Nagar, Vidya S., Basavaraj Sajjan, Rudrarpan Chatterjee, and Nitesh M. Parab. "The comparison of apache II and apache IV score to predict mortality in intensive care unit in a tertiary care hospital." International Journal of Research in Medical Sciences 7, no. 5 (2019): 1598. http://dx.doi.org/10.18203/2320-6012.ijrms20191643.

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Background: The prognostication of critically ill patients, in a systematic way, based on definite objective data is an integral part of the quality of care in Intensive Care Unit (ICU). Acute physiology and chronic health evaluation (APACHE) scoring systems provide an objective means of mortality prediction in Intensive Care Unit (ICU). The aims of this study were to compare the performance of APACHE II and APACHE IV in predicting mortality in our intensive care unit (ICU).Methods: A prospective observational study was conducted in a 13 bedded intensive care unit (ICU) of a tertiary level tea
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Azhough, Ramin, Reza Movassaghi, and Ali Farbod. "Thyroid Function as a Predictive Tool for The Prognosis of Traumatic Patients Admitted in Surgery ICUs." Advances in Bioscience and Clinical Medicine 5, no. 3 (2017): 14. http://dx.doi.org/10.7575/aiac.abcmed.17.05.03.04.

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Background: APACHE Score is an important criterion for determining the patient prognosis, especially in critically ill patients. According to significantly changes in the serum levels of thyroidal hormones in patients, especially in critically ill patients, the aim of the present study was to evaluate the relationship between thyroid function and APACHE 4 score in the prognosis of the traumatic patients admitted in surgery ICU. Method &amp; Material: In a descriptive-analytical study, 90 patients with multiple trauma were studied. Thyroid hormones and APACHE 4 Score were evaluated on 1st, 5th
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Arslan, Kadir, Ümmihan Topal, and Ayça Sultan Şahin. "Computerized Tomography-Based Scoring Systems (Marshall and Rotterdam score) versus Physiological Scoring Systems (GCS and APACHE II score) in Predicting Mortality in Traumatic Brain Injury." Clinical and Experimental Health Sciences 15, no. 1 (2025): 83–89. https://doi.org/10.33808/clinexphealthsci.1457777.

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Objective: Since traumatic brain injury (TBI) has high mortality rates, it is essential to identify patients with poor prognosis. In this study, the mortality prediction performances of the Glasgow Coma Scale (GCS), Acute Physiology and Chronic Health Assessment-II (APACHE-II), Marshall, and Rotterdam scores were compared in patients with TBI in the intensive care unit (ICU) of a tertiary center. Methods: Patients followed up in the ICU due to moderate to severe TBI between January 2020 and January 2022 were retrospectively reviewed. Patients were classified as survivor and nonsurvivor groups.
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Rehman, Sami Ur, Unaiza Saeed, Asif Ali, Muhammad Malik, Saran Ghani, and Eesha Rehman. "Role of APACHE-II Score in Predicting The Incidence of Ventilator-Associated Pneumonia in Intensive Care Unit Patients." Biological and Clinical Sciences Research Journal 6, no. 1 (2025): 101–5. https://doi.org/10.54112/bcsrj.v6i1.1323.

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A prevalent nosocomial infection in the intensive care unit (ICU) is ventilator-associated pneumonia (VAP). VAP is defined as pneumonia in individuals with invasive mechanical ventilation during the preceding 48 hours; it affects 5–40% of patients with invasive mechanical ventilation. These scoring systems forecast the mortality, hence the disease’s prognosis, which is very important in limited health resources and an increased cost of health management. ICU staff and doctors are highly recommended to be familiar with using the APACHE-II scoring system. The three main components of the APACHE-
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Manerikar, Sangeeta, and Seetharaman Hariharan. "Do Serially Recorded Prognostic Scores Predict Outcome Better Than One-Time Recorded Score on Admission? A Prospective Study in Adult Intensive Care Patients." Journal of Intensive Care Medicine 32, no. 8 (2016): 480–86. http://dx.doi.org/10.1177/0885066615625937.

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Objectives: The prognosticating ability of one-time recorded Acute Physiology and Chronic Health Evaluation (APACHE) IV score was compared with serially recorded Mortality Prediction Model (MPM) II scores. Design and Methods: A prospective observational study was conducted for a period of 6 months. Acute Physiology and Chronic Health Evaluation IV score was recorded during the first day on intensive care unit (ICU) admission. Mortality Prediction Model II was recorded on admission, 24, 48, and 72 hours. Predicted mortality was compared with observed mortality. The systems were calibrated and t
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Thakur, Saritesh Kumar, Pallavi Indurkar, Dinesh Kumar Malviya, and Manoj Indurkar. "Study of APACHE II score and National Institutes of Health Stroke Scale as prognostic indicators in cerebrovascular accidents patients admitted in a tertiary care center, Rewa." Asian Journal of Medical Sciences 13, no. 5 (2022): 131–35. http://dx.doi.org/10.3126/ajms.v13i5.43985.

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Background: Stroke is the 2nd largest cause of mortality world over. In the intensive care unit (ICU), severity scales are crucial adjuncts of treatment for anticipating patient outcomes, comparing quality of care, and stratification for clinical studies. They are an important aspect of making better health-care judgments and identifying people with unusual outcomes. This study was conducted to assess and compare Acute Physiology and Chronic Health Evaluation II (APACHE II) score and National Institutes of Health Stroke Scale (NIHSS) score as predictors of mortality in cerebrovascular accident
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Joyia, Manzoor Qadir, Mudassar Murtaza, Mohammad Ansar Aslam, Fakhar Irfan, Hira Liaqat, and Ahmed Raza Naumani. "Predictive accuracy of Apache-II for mortality in Poly Trauma patients." Professional Medical Journal 27, no. 11 (2020): 2314–19. http://dx.doi.org/10.29309/tpmj/2020.27.11.4460.

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Objectives: The objective of our study was to find diagnostic accuracy of APACHE-II score to predict mortality in poly trauma patients within first 24 hours of hospitalization. Study Design: Cross Sectional study. Setting: Department of Emergency Lahore General Hospital. Period: 25 March, 2016 to 25 September, 2016. Material &amp; Methods: A total of 230 patients who fulfilled inclusion criteria were enrolled in the study from emergency department of Lahore General Hospital, informed consent was taken from all patients or their attendants to take their demographic profile (name, age, gender an
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Li, Lei, Yanfen Yao, and Shanshan Liu. "The Value of Pulmonary Bedside Ultrasound System in the Evaluation of Severity and Prognosis of Acute Lung Injury." Computational and Mathematical Methods in Medicine 2022 (January 27, 2022): 1–7. http://dx.doi.org/10.1155/2022/6471437.

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Objective. To evaluate the value of pulmonary bedside ultrasound system in the assessment of severity and prognosis of acute lung injury (ALI). Method. Seventy-two ALI patients in the intensive care unit (ICU) of our hospital from April 2019 to April 2021 were selected as subjects. The changes of lung ultrasound score (LUS) and parameters at D1, D2, and D3 after admission were analyzed (LUS, oxygenation index (PaO2/FiO2), Acute Physiology and Chronic Health Evaluation II (APACHE-II), and Sequential Organ Failure Assessment (SOFA) score). Pearson correlation analysis was used to assess the rela
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Cheng, Jocelyn Y. "Mortality prediction in status epilepticus with the APACHE II score." Journal of the Intensive Care Society 18, no. 4 (2017): 310–17. http://dx.doi.org/10.1177/1751143717715967.

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A retrospective study was performed of adults admitted to the intensive care unit in order to determine the utility of the Acute Physiology and Chronic Health Evaluation II (APACHE II) score in predicting in-hospital mortality in intensive care unit patients with non-cardiac status epilepticus. The cohort consisted of 104 subjects, 50 (48.1%) male, 39 (37.5%) aged ≥65 years, with a mean APACHE II score of 17.88. Four models of the APACHE II system were assessed: numerical score, adjusted score mortality, category, and category mortality. All models demonstrated poor calibration and discriminat
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Aslan, Sefer, Kubilay İşsever, Serdar Olt, Emre Yilmaz, Ersin Kuloğlu, and Ayşe Şahin Tutak. "APACHE II-ECG scoring system: A novel and strong predictor of in-hospital mortality for patients treated in intensive care unit." Medicine 103, no. 52 (2024): e41121. https://doi.org/10.1097/md.0000000000041121.

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Some novel electrocardiographic (ECG) parameters, such as T-wave peak to T-wave end duration (Tp-Te) and Tp-Te/Q-T interval (QT) ratios, have recently been found to be associated with cardiac ischemia and effective in predicting ventricular arrhythmias and mortality. This study examined the association between ECG repolarization parameters and mortality in intensive care unit (ICU) patients. A total of 232 ICU patients were retrospectively categorized as survivors or nonsurvivors retrospectively. Laboratory, demographic, and ECG parameters were compared between the groups. A novel ECG score wa
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Colmenero, Manuel. "Mortality discrimination in acute myocardial infarction: comparison between APACHE III and SAPS II prognosis systems." Intensive Care Medicine 1997; 23:326-330. 23, no. 3 (1997): 326–30. https://doi.org/10.1007/s001340050335.

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<em>Objective:</em>&nbsp;To compare the Acute Physiology, Age and Chronic Health Evaluation (APACHE) III with the Simplified Acute Physiology Score (SAPS II) in discriminating in-hospital mortality for intensive care unit (ICU) patients with acute myocardial infarction (AMI).&nbsp;<em>Design:</em>&nbsp;Prospective, observational, multicenter study.&nbsp;<em>Setting:</em>&nbsp;70 Spanish ICUs.&nbsp;<em>Patients and participants:</em>&nbsp;1711 patients with AMI and representative of Spanish ICUs.&nbsp;<em>Measurements and results:</em>&nbsp;APACHE III score, APACHE III system probability of dea
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Joyson, Sunil, and H. S. Kiran. "Red Cell Distribution Width and Platelet Volume Indices in Critically III Patients." Journal of Datta Meghe Institute of Medical Sciences University 16, no. 1 (2021): 115–20. http://dx.doi.org/10.4103/jdmimsu.jdmimsu_148_19.

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Background: Red cell distribution width (RDW) is the quantitative assessment of variation of the size of circulating red blood cells. Platelet volume indices include mean platelet volume (MPV) and platelet distribution width (PDW). Few studies have evaluated RDW and platelet volume indices in critically ill patients. The objective of this study was to assess RDW and platelet volume indices in critically ill patients. Methods: It was a prospective observational study. The study included 260 critically ill patients (irrespective of diagnosis) admitted in intensive care units (ICUs) under the dep
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Chavanda, Sneha R., and Rajendra R. Mane. "Correlation of Thyroid Hormones in the Prognosis of Critically Ill Patients." Siriraj Medical Journal 73, no. 3 (2021): 161–66. http://dx.doi.org/10.33192/smj.2021.21.

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Objective: Non-thyroidal illness syndrome (NTIS) is associated with outcomes in Intensive Care Unit(ICU) patients. The objectives of the study were to assess the prognostic value of complete thyroid profile in critically ill patients and to determine the effect of thyroid hormone level in predicting mortality when used along with acute physiology and chronic health evaluation (APACHE) II score.Methods: The observational study was conducted at a tertiary care centre in Kolhapur, India. Critically ill adult patients admitted to intensive care units with APACHE II &gt;10 was included(n=50). Relev
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Agarwal, Anand, Ganpat Singh Choudhary, Mansingh Bairwa, and Amit Choudhary. "Apache II scoring in predicting surgical outcome in patients of perforation peritonitis." International Surgery Journal 4, no. 7 (2017): 2321. http://dx.doi.org/10.18203/2349-2902.isj20172790.

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Background: Many scoring systems have been found useful in predicting the outcome in critically ill patients, amongst them acute physiology and chronic health evaluation score (APACHE II) appeared to be the most widely used and had a general acceptance in assessing the critically ill patients, for its easy applicability and ability to predict outcome.Methods: To predict the surgical outcome in patients of perforation peritonitis APACHE II scoring done in every diagnosed case of perforation peritonitis in a prospective study from January 2015 to June 2016 was done. 100 patients with perforation
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Vandenbrande, Jeroen, Laurens Verbrugge, Liesbeth Bruckers, et al. "Validation of the Acute Physiology and Chronic Health Evaluation (APACHE) II and IV Score in COVID-19 Patients." Critical Care Research and Practice 2021 (June 19, 2021): 1–9. http://dx.doi.org/10.1155/2021/5443083.

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Background. Severity scoring systems are inherent to ICU practice for multiple purposes. Acute Physiology and Chronic Health Evaluation (APACHE) scoring systems are designed for ICU mortality prediction. This study aims to validate APACHE IV in COVID-19 patients admitted to the ICU. Methods. All COVID-19 patients admitted to the ICU between March 13, 2020, and October 17, 2020, were retrospectively analyzed. APACHE II and APACHE IV scores as well as SOFA scores were calculated within 24 hours after admission. Discrimination for mortality of all three scoring systems was assessed by receiver op
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Maran, Jyoti S., Archana Shukla, and Bhupendra Singh Parmar. "Mannheim’s peritonitis index a more simpler prognostic index than APACHE II score." International Surgery Journal 7, no. 9 (2020): 3041. http://dx.doi.org/10.18203/2349-2902.isj20203791.

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Background: The study was done with the aim to determine the clinical profile of patients with hollow viscous perforation and to compare MPI and APACHE II scoreMethods: This study was a prospective and retrospective observational study conducted in the department of General Surgery, Gandhi Medical College and associated Hamidia Hospital from the June 2017 to August 2019The possible score ranges from 0-47. All necessary preoperative data was recorded. Blood sample was taken and relevant blood investigations were done. Patients were resuscitated with iv fluids. Nasogastric tube and urinary cathe
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Islam, Md Sayedul. "APHACHE Score as a Predictive Indices for Weanability from Mechanical Ventilation." Bangladesh Critical Care Journal 1, no. 1 (2013): 18–22. http://dx.doi.org/10.3329/bccj.v1i1.14360.

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Objective: To determine the significance of acute physiology and chronic health evaluation (APACHE) score as an important parameter of weaning outcome for mechanical ventilation. Design: prospective, observational. Setting: The medical ICU of a modernized private hospital, Dhaka. Method: The study was carried out during the period of 2008 to 2009 in a specialized private hospital Dhaka. Critical care physicians were asked to filled up the data sheets having detail problem of the patients including the APACHE II score. The APACHE II score is divided into three steps High score&gt;25, Medium sco
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Kostoglou, Ariadni, Anastasia Kotanidou, Christina Marvaki, and Stylianos Orfanos. "Mortality rate of ICU patients according to APACHE II and SAPS II score." Health & Research Journal 4, no. 4 (2018): 219. http://dx.doi.org/10.12681/healthresj.19297.

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Introduction: Two of the most important systems measuring the severity of disease classification in Intensive Care Unit (ICU) are APACHE II and SAPS II. The scores that the two systems generate can be the cause of increased mortality.Aim: of subject study is to record mortality of 28 days in ICU of a Hospital located in Piraeus and to investigate its dependence on the variables APACHE II and SAPS II. Material and Methods: Population of the study consisted of 200 patients, older than 18 years, admitted to ICU. The application of normal distribution for continuous variables has been evaluated ba
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Jianmin, Qiu, You Xueliang, Liu Liqin, Wu Yongsheng, He Licang, and Huang Yuanxin. "Value of continuous video EEG and EEG responses to thermesthesia stimulation in prognosis evaluation of comatose patients after cardiopulmonary resuscitation." Open Medicine 13, no. 1 (2018): 35–40. http://dx.doi.org/10.1515/med-2018-0006.

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AbstractObjectiveTo investigate the clinical value of video-electroencephalography (VEEG) and thermal stimulus on evaluating the prognosis of comatose patients after cardiopulmonary resuscitation.MethodsTwenty eight comatose patients with cardiopulmonary resuscitation were included in the department of ICU of the First Teaching Hospital of Fujian Medical University from February 2013 to March 2016. Of the included 28 patients, 20 cases died (death group) and 8 cases survived (survival group) after cardiopulmonary resuscitation. The VEEG, Glasgow Coma Scale (GCS) and APACHE II score were record
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Modi, Jenish Vijaykumar, and Jenish Sheth. "Observational study of comparison of BISAP score with Ranson’s score and APACHE II scores in assessing severity and prognosis in patients of acute pancreatitis." International Surgery Journal 6, no. 1 (2018): 178. http://dx.doi.org/10.18203/2349-2902.isj20185468.

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Background: Acute pancreatitis is one of the most common diseases of gastrointestinal tract, leading to tremendous emotional, physical and financial burden. Acute pancreatitis is an acute inflammation of the prior normal gland parenchyma which is usually reversible (but acute attack can occur in a pre-existing chronic pancreatitis) with raised pancreatic enzyme levels in blood and urine. It may be first attack or relapsing attacks with an apparently normal gland in between. Biliary tract disease and alcoholism are the commonest cause of pancreatitis.Methods: It was an observational study at Su
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Kumar, Lokesh, Sunita Singh, Dhirendra Pratap, et al. "Comparison of predictive values of Mannheim peritonitis index, acute physiology and chronic health evaluation-II and Portsmouth-POSSUM scoring systems for prognosis of mortality in patients with perforation peritonitis." International Journal of Research in Medical Sciences 10, no. 5 (2022): 1059. http://dx.doi.org/10.18203/2320-6012.ijrms20221176.

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Background: Perforation peritonitis has emerged as one of the very common cause of surgical emergencies, particularly in developing countries like India. If left untreated for long due to improper prognosis or late diagnosis, perforation peritonitis may prove potentially fatal with a high mortality and morbidity rate. Scoring systems like APACHE-II (acute physiology and chronic health evaluation), p-POSSUM (Portsmouth-POSSUM) and MPI (Mannheim peritonitis index) may serve as simple, critical, and efficient prognostic tools in predicting the mortality in patients with perforation peritonitis. T
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