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Thèses sur le sujet « Assembly and disassembly »

Auteur : Grafiati

Publié le 4 mai 2024

Mis à jour le 19 juillet 2025

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1

Shanmugam, Sivamoorthy. "Automatic Sub-assembly detection, disassembly sequencing and disassembly direction prediction for an assembly model." Cincinnati, Ohio : University of Cincinnati, 2005. http://www.ohiolink.edu/etd/view.cgi?acc%5Fnum=ucin1109252927.

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SHANMUGAM, SIVAMOORTHY. "AUTOMATIC SUB-ASSEMBLY DETECTION, DISASSEMBLY SEQUENCING AND DISASSEMBLY DIRECTION PREDICTOR FOR AN ASSEMBLY MODEL." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1109252927.

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3

Baker, Michael. "The assembly and disassembly of clathrin cages." Thesis, University of Warwick, 2016. http://wrap.warwick.ac.uk/89475/.

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Clathrin mediated endocytosis (CME) is an integral process in eukaryotic cells and governs a wide range of processes in higher organisms including neurotransmitter release and cell signalling, to development and cell polarity. Due to its wide ranging roles this mechanism has been implicated in various disease states such as Huntington’s disease and various cancers as well as being a method of entry into cells for many viruses and bacteria. The process of CME involves the formation of a clathrin coat, primarily consisting of the protein clathrin, that drives uptake of cargo at the plasma membra

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4

Schoen, Timothy Ryan. "Constraint-aware distributed robotic assembly and disassembly." Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/77078.

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Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2012.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 83-85).<br>In this work, we present a distributed robotic system capable of the efficient assembly and disassembly of complex three-dimensional structures. We introduce algorithms for equitable partitioning of work across robots and for the efficient ordering of assembly or disassembly tasks while taking physical constraints into consideration. We then extend these algorithms to a variety of real

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5

Sung, Raymond Chun Wai. "Automatic assembly feature recognition and disassembly sequence generation." Thesis, Heriot-Watt University, 2001. http://hdl.handle.net/10399/478.

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Mohd, Rashid Aiman. "Disassembly and assembly in the Malay building culture." Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/22827/.

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Asian vernacular architecture is generally dynamic, progressing and constantly transforming. The significance of Asian vernacular values lies in the culture, identity and memory of the people rather than the fabric or preserved artefacts. Likewise, the vernacular traditional Malay houses are a manifestation of the craft process and meanings embodied in the people, their building practice and artefacts. However, the Malay building culture is diminishing while the numbers of tukang or master craftsmen is declining, which adds to the loss of traditional knowledge and skills in Malay house buildin

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Duggan, James. "Soluble factors affecting the assembly and disassembly of membrane rafts." Thesis, University of Nottingham, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495061.

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The presence of membrane microdomains or rafts within cell membranes is an area of intensive research and debate, with the notion of intracellular membrane rafts proving particularly contentious. The full extent of their biological importance is unknown but, they do appear to have vital roles in key processes such as membrane transport and cell signalling. They have been shown to have significant involvement in the formation of the immunological synapse and subsequent immune cell activation. Their cellular functions are also hijacked by various pathogens such as the human immunodeficiency viru

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Lane, Laura Alexandra. "Assembly and disassembly of protein complexes : insights from mass spectrometry." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608969.

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9

Chromy, Laura R. "The role of HSP70 chaperones in papovavirus disassembly and assembly /." Connect to full text via ProQuest. Limited to UCD Anschutz Medical Campus, 2007.

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Thesis (Ph.D. in Molecular Biology) -- University of Colorado Denver, 2007.<br>Typescript. Includes bibliographical references (leaves 142-165). Free to UCD affiliates. Online version available via ProQuest Digital Dissertations;

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10

Chang, Piyen. "Selection and evaluation of joint types and joining processes for concurrent assembly/disassembly-based design." Thesis, This resource online, 1996. http://scholar.lib.vt.edu/theses/available/etd-09182008-063034/.

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11

Lurgi, Rivera Miguel. "The assembly and disassembly of ecological networks in a changing world." Doctoral thesis, Universitat Autònoma de Barcelona, 2014. http://hdl.handle.net/10803/133289.

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El ensamblaje, estructuración y funcionamiento de las comunidades naturales, compuestas de muchas especies que forman redes complejas de interacciones ecológicas, ha desconcertado a los ecólogos durante muchas generaciones. Investigación ecológica pionera determinó que el tamaño de la comunidad y su complejidad (medida como la conectividad en la red de interacciones ecológicas) limita la estabilidad de la comunidad, y por lo tanto impiden que las comunidades sean indefinidamente complejas o ricas en especies. Investigación

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12

Vaillant, Dominique. "Evaluation of mammalian cell-free systems of nuclear assembly and disassembly." Thesis, University of Ottawa (Canada), 2005. http://hdl.handle.net/10393/27066.

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Mammalian cell-free systems are very useful for the biochemical and structural study of nuclear disassembly and assembly. Through manipulation, the role of specific proteins in these processes can be investigated. I first intended to examine the involvement of integral and peripheral inner nuclear membrane proteins in nuclear disassembly and assembly. However, I was unable to achieve disassembly when isolated interphase HeLa nuclei were exposed to mitotic soluble extracts containing cyclin B1. Homogenates of synchronized mitotic HeLa cells left to reassemble nuclei resulted in incomplete nucle

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13

Sept, David S. "Models of assembly and disassembly of individual microtubules and their ensembles." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/nq23068.pdf.

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DESAI, ANOOP. "AN INTEGRATED METHODOLOGY FOR ASSEMBLY, DISASSEMBLY AND MAINTENANCE FOR CONSUMER PRODUCTS." University of Cincinnati / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1154100938.

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15

Tison, Christopher Kirby. "Programmable, isothermal disassembly of DNA-linked colloidal particles." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/28189.

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Thesis (M. S.)--Materials Science and Engineering, Georgia Institute of Technology, 2009.<br>Committee Chair: Milam, Valeria; Committee Member: Boyan, Barbara; Committee Member: Li, Mo; Committee Member: McDevitt, Todd; Committee Member: Sandhage, Ken.

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Eze, Ngozi A. "Implementing locked nucleic acids as a bioinspired colloidal assembly and disassembly tool." Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/51789.

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Oligonucleotides are popular recognition-based biomaterials assembly and disassembly tools due to their specificity and ease of control. Their susceptibility to degradation by nucleases and false positive signals under certain conditions, however, has led to great interest in chemically modified oligonucleotides such as locked nucleic acids (LNA) that enhance both nuclease resistance and target specificity. This dissertation extends prior work with DNA sequences to investigate incorporating locked nucleic acid (LNA), a synthetic oligonucleotide, in isothermal colloidal assembly and disassembly

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17

Geerts, Sjirk. "Assembly and disassembly of bird pollination communities at the Cape of Africa." Thesis, Stellenbosch : Stellenbosch University, 2011. http://hdl.handle.net/10019.1/6904.

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Thesis (PhD (Botany and Zoology))--Stellenbosch University, 2011.<br>ENGLISH ABSTRACT: With the current global decline in pollinators, and the concurrent decline in plant species, pollination research is becoming increasingly important. However, studies outside Europe and North-America and on groups other than insects are needed to make generalisations possible. In this thesis I study how pollination structures plant and bird communities in a biodiversity hotspot, the Cape Floristic Region of South Africa. I show that bird-plant pollination mutualisms are an important ecological factor structu

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June, Stephen Matthew. "Step-Growth Polymerization Towards the Design of Polymers: Assembly and Disassembly of Macromolecules." Diss., Virginia Tech, 2012. http://hdl.handle.net/10919/37619.

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Step-growth polymerization provided an effective method for the preparation of several high performance polymers. Step-growth polymerization was used for syntheses of poly(siloxane imides), polyesters, poly(triazole esters), poly(triazole ether esters), and epoxy networks. Each of these polymeric systems exhibited novel structures, and either photoreactive capabilities, or high performance properties. There is an increasing trend towards the development of photoactive adhesives. In particular these polymers are often used in flip bonding, lithography, stimuli responsive polymers, drug deli

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Coutee, Adam S. "Virtual Assembly and Disassembly Analysis: An Exploration into Virtual Object Interactions and Haptic Feedback." Diss., Available online, Georgia Institute of Technology, 2004:, 2004. http://etd.gatech.edu/theses/available/etd-05272004-174324/unrestricted/coutee%5adam%5s%5200407%5phd.pdf.

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Thesis (Ph. D.)--School of Mechanical Engineering, Georgia Institute of Technology, 2005. Directed by Bert Bras.<br>Bras, Bert, Committee Chair ; Baker, Nelson, Committee Member ; Griffin, Paul, Committee Member ; Paredis, Chris, Committee Member ; Rosen, David, Committee Member. Vita. Includes bibliographical references.

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20

Cheng, Xi. "Dynamic assembly, disassembly and bundling of the bacterial cell division protein FtsZ and YgfE (ZapA)." Thesis, University of Warwick, 2011. http://wrap.warwick.ac.uk/49617/.

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The protein FtsZ is a tubulin-like GTPase, which plays an essential role in prokaryotic cell division. In vivo it assembles into a dynamic ring (the Z-ring) at the future site of cell division on the inner surface of the cytoplasmatic membrane. The Z-ring then serves as a scaffold which recruits all other division proteins to form the cytokinetic machinery. The constriction of the ring facilitates the separation of two daughter cells. In vitro, FtsZ polymerizes in the presence of GTP to form single-stranded protofilaments. It is assumed that FtsZ association and assembly reactions studied in v

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Ford, Robert John. "The roles of RNA in the assembly and disassembly of single-stranded RNA icosahedral viruses." Thesis, University of Leeds, 2012. http://etheses.whiterose.ac.uk/4135/.

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Single-stranded, positive-sense icosahedral viruses are major pathogens in every kingdom of life. Despite this, their capsid assembly and uncoating mechanisms remain poorly understood. This work describes these processes in two model systems; satellite tobacco necrosis virus and turnip crinkle virus. For satellite tobacco necrosis virus, several aptamers were previously raised against the coat protein, where each aptamer folded into stem-loops displaying the motif AXXA. Aptamer B3 contained the strongest sequence similarity to the cognate genome, including a 10/10 contiguous stretch. Capsid as

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22

Campos, González Roberto. "Calmodulin and the assembly and disassembly of microtubules during the mitogenic stimulation of mouse T lymphocytes." Thesis, University of Ottawa (Canada), 1987. http://hdl.handle.net/10393/5323.

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23

English, Christine Marie. "Insights into chromatin assembly through the characterization of the histone chaperone ASF1 bound to histones H3-H4 /." Connect to full text via ProQuest. Limited to UCD Anschutz Medical Campus, 2006.

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Thesis (Ph.D. in Biochemistry & Molecular Genetics) -- University of Colorado at Denver and Health Sciences Center, 2006.<br>Typescript. Includes bibliographical references (leaves 169-185). Free to UCD Anschutz Medical Campus. Online version available via ProQuest Digital Dissertations;

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Keenen, Bridget A. "The role of SWI/SNF chromatin remodeling enzymes in melanoma." Toledo, Ohio : University of Toledo, 2010. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=mco1271819328.

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Dissertation (Ph.D.)--University of Toledo, 2010.<br>"Submitted to the Graduate Faculty as partial fulfillment of the requirements for the Doctor of Philosophy Degree in Biomedical Sciences." Title from title page of PDF document. "A Dissertation entitled"--at head of title. Bibliography: p. 63-71, 126-140.

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Swygert, Sarah G. "The Shape of Silence: The Solution-State Conformation of Sir Heterochromatin: A Dissertation." eScholarship@UMMS, 2015. http://escholarship.umassmed.edu/gsbs_diss/790.

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Heterochromatin is a silenced chromatin region essential for maintaining genomic stability in eukaryotes and for driving developmental processes in higher organisms. A hallmark of heterochromatin is the presence of specialized architectural proteins that alter chromatin structure to inhibit transcription and recombination. Although it is generally assumed that heterochromatin is highly condensed, surprisingly little is known about the structure of heterochromatin or its dynamics in solution. In budding yeast, heterochromatin assembly at telomeres and the HM silent mating type loci requires the

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Letienne, Justine [Verfasser], and Christine [Akademischer Betreuer] Blattner. "Impact of Mdm2-p53 on the proteasome assembly and disassembly Role of the ubiquitination of some 19S subunits / Justine Letienne. Betreuer: Christine Blattner." Karlsruhe : KIT-Bibliothek, 2011. http://d-nb.info/101691959X/34.

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27

Alam, Syed Benazir. "Study of the role of viral coat protein and host factor HSP70 homologs in the assembly and disassembly of Cucumber necrosis virus particles." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/61781.

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Virion assembly and disassembly are crucial aspects of the virus multiplication cycle, however, relatively little is known about these processes in plant viruses. While the former helps to produce multiple copies of stable infectious progeny virions, the latter is required for release of the encapsidated viral genome into a host cell for initiating new rounds of virus multiplication. In this thesis, I aimed to study Cucumber necrosis virus (CNV) particle assembly and disassembly and the role of CNV coat protein (CP) and host HSP70 homologs in these processes. It was found that CNV infection o

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Manning, Benjamin J. "ATP-Dependent Heterochromatin Remodeling: A Dissertation." eScholarship@UMMS, 2015. https://escholarship.umassmed.edu/gsbs_diss/795.

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Eukaryotic DNA is incorporated into the nucleoprotein structure of chromatin. This structure is essential for the proper storage, maintenance, regulation, and function of the genomes’ constituent genes and genomic sequences. Importantly, cells generate discrete types of chromatin that impart distinct properties on genomic loci; euchromatin is an open and active compartment of the genome, and heterochromatin is a restricted and inactive compartment. Heterochromatin serves many purposes in vivo, from heritably silencing key gene loci during embryonic development, to preventing aberrant DNA repea

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Manning, Benjamin J. "ATP-Dependent Heterochromatin Remodeling: A Dissertation." eScholarship@UMMS, 2009. http://escholarship.umassmed.edu/gsbs_diss/795.

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Eukaryotic DNA is incorporated into the nucleoprotein structure of chromatin. This structure is essential for the proper storage, maintenance, regulation, and function of the genomes’ constituent genes and genomic sequences. Importantly, cells generate discrete types of chromatin that impart distinct properties on genomic loci; euchromatin is an open and active compartment of the genome, and heterochromatin is a restricted and inactive compartment. Heterochromatin serves many purposes in vivo, from heritably silencing key gene loci during embryonic development, to preventing aberrant DNA repea

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Silveira, Alexandra C. "Characterization of SUDS3 as a BRMS1 family member in breast cancer." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2008p/silveira.pdf.

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Hughes, Amanda L. "Dissecting cis and trans Determinants of Nucleosome Positioning: A Dissertation." eScholarship@UMMS, 2014. https://escholarship.umassmed.edu/gsbs_diss/743.

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Eukaryotic DNA is packaged in chromatin, whose repeating subunit, the nucleosome, consists of an octamer of histone proteins wrapped by about 147bp of DNA. This packaging affects the accessibility of DNA and hence any process that occurs on DNA, such as replication, repair, and transcription. An early observation from genome-wide nucleosome mapping in yeast was that genes had a surprisingly characteristic structure, which has motivated studies to understand what determines this architecture. Both sequence and trans acting factors are known to influence chromatin packaging, but the relative con

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Hughes, Amanda L. "Dissecting cis and trans Determinants of Nucleosome Positioning: A Dissertation." eScholarship@UMMS, 2011. http://escholarship.umassmed.edu/gsbs_diss/743.

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Eukaryotic DNA is packaged in chromatin, whose repeating subunit, the nucleosome, consists of an octamer of histone proteins wrapped by about 147bp of DNA. This packaging affects the accessibility of DNA and hence any process that occurs on DNA, such as replication, repair, and transcription. An early observation from genome-wide nucleosome mapping in yeast was that genes had a surprisingly characteristic structure, which has motivated studies to understand what determines this architecture. Both sequence and trans acting factors are known to influence chromatin packaging, but the relative con

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Walfridsson, Julian. "The CHD chromatin remodeling factors in schizosaccharomyces pombe /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-106-7/.

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Junius, Meike Pauline Wilhelmine [Verfasser], Ulf [Akademischer Betreuer] [Gutachter] Diederichsen, and Reinhard [Gutachter] Jahn. "Synthesis and Analysis of Modified SNARE Proteins with Respect to Assembly and Disassembly of the SNARE Complex / Meike Pauline Wilhelmine Junius ; Gutachter: Ulf Diederichsen, Reinhard Jahn ; Betreuer: Ulf Diederichsen." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2017. http://d-nb.info/1123283036/34.

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Linger, Jeffrey G. "The role of histone chaperones in double-strand DNA repair and replication-independent histone exchange /." Connect to full text via ProQuest. IP filtered, 2006.

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Thesis (Ph.D. in Biochemistry) -- University of Colorado, 2006.<br>Typescript. Includes bibliographical references (leaves 153-171). Free to UCDHSC affiliates. Online version available via ProQuest Digital Dissertations;

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Yang, Xiaofang. "Functional and Structural Dissection of the SWI/SNF Chromatin Remodeling Complex: A Dissertation." eScholarship@UMMS, 2007. https://escholarship.umassmed.edu/gsbs_diss/330.

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The yeast SWI/SNF complex is the prototype of a subfamily of ATP-dependent chromatin remodeling complexes. It consists of eleven stoichiometric subunits including Swi2p/Snf2p, Swi1p, Snf5p, Swi3p, Swp82p, Swp73p, Arp7p, Arp9p, Snf6p, Snf11p, and Swp29p, with a molecular weight of 1.14 mega Daltons. Swi2p/Snf2p, the catalytic subunit of SWI/SNF, is evolutionally conserved from yeast to human cells. Genetic evidence suggests that SWI/SNF is required for the transcriptional regulation of a subset of genes, especially inducible genes. SWI/SNF can be recruited to target promotors by gene specific a

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Marfella, Concetta G. A. "The Role of CHD2 in Mammalian Development and Disease: a Dissertation." eScholarship@UMMS, 2007. http://escholarship.umassmed.edu/gsbs_diss/334.

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Chromatin structure is intricately involved in the mechanisms of eukaryotic gene regulation. In general, the compact nature of chromatin blocks DNA accessibility such that components of the transcriptional machinery are unable to access regulatory sequences and gene activation is repressed. These repressive effects can be overcome or augmented by the actions of chromatin remodeling enzymes. Numerous studies highlight two classes of these enzymes: those that covalently modify nucleosomal histones and those that utilize energy derived from ATP hydrolysis to destabilize the histone-DNA contacts w

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Kolpa, Heather J. "XIST and CoT-1 Repeat RNAs are Integral Components of a Complex Nuclear Scaffold Required to Maintain SAF-A and Modify Chromosome Architecture: A Dissertation." eScholarship@UMMS, 2016. https://escholarship.umassmed.edu/gsbs_diss/825.

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XIST RNA established the precedent for a noncoding RNA that stably associates with and regulates chromatin, however it remains poorly understood how such RNAs structurally associate with the interphase chromosome territory. I demonstrate that transgenic XIST RNA localizes in cis to an autosome as it does to the inactive X chromosome, hence the RNA recognizes a structure common to all chromosomes. I reassess the prevalent thinking in the field that a single protein, Scaffold Attachment Factor-A (SAF-A/hnRNP U), provides a single molecule bridge required to directly tether the RNA to DNA. In an

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Kolpa, Heather J. "XIST and CoT-1 Repeat RNAs are Integral Components of a Complex Nuclear Scaffold Required to Maintain SAF-A and Modify Chromosome Architecture: A Dissertation." eScholarship@UMMS, 2004. http://escholarship.umassmed.edu/gsbs_diss/825.

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XIST RNA established the precedent for a noncoding RNA that stably associates with and regulates chromatin, however it remains poorly understood how such RNAs structurally associate with the interphase chromosome territory. I demonstrate that transgenic XIST RNA localizes in cis to an autosome as it does to the inactive X chromosome, hence the RNA recognizes a structure common to all chromosomes. I reassess the prevalent thinking in the field that a single protein, Scaffold Attachment Factor-A (SAF-A/hnRNP U), provides a single molecule bridge required to directly tether the RNA to DNA. In an

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Burns, Loree Griffin. "In Vivo Functional Analysis of the Saccharomyces Cerevisiae SWI/SNF Complex: A Dissertation." eScholarship@UMMS, 1997. https://escholarship.umassmed.edu/gsbs_diss/202.

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Chromatin remodeling is crucial to transcriptional regulation in vivo and a number of protein complexes capable of altering genomic architecture in the budding yeast Saccaromyces cerevisiaehave been identified. Among these, the SWI/SNF complex, a 2 MDa, eleven subunit protein assembly, has been the most extensively characterized. The SWI/SNF complex is required for the proper expression of a number of genes in yeast, although it is completely dispensable for the expression of others. Likewise, some, but not all, transcriptional activator proteins require SWI/SNF activity in order to function i

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Bennett, Gwendolyn M. "Chromatin Regulators and DNA Repair: A Dissertation." eScholarship@UMMS, 2014. https://escholarship.umassmed.edu/gsbs_diss/742.

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DNA double-strand break (DSB) repair is essential for maintenance of genome stability. However, the compaction of the eukaryotic genome into chromatin creates an inherent barrier to any DNA-mediated event, such as during DNA repair. This demands that there be mechanisms to modify the chromatin structure and thus access DNA. Recent work has implicated a host of chromatin regulators in the DNA damage response and several functional roles have been defined. Yet the mechanisms that control their recruitment to DNA lesions, and their relationship with concurrent histone modifications, remain unclea

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Bennett, Gwendolyn M. "Chromatin Regulators and DNA Repair: A Dissertation." eScholarship@UMMS, 2012. http://escholarship.umassmed.edu/gsbs_diss/742.

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DNA double-strand break (DSB) repair is essential for maintenance of genome stability. However, the compaction of the eukaryotic genome into chromatin creates an inherent barrier to any DNA-mediated event, such as during DNA repair. This demands that there be mechanisms to modify the chromatin structure and thus access DNA. Recent work has implicated a host of chromatin regulators in the DNA damage response and several functional roles have been defined. Yet the mechanisms that control their recruitment to DNA lesions, and their relationship with concurrent histone modifications, remain unclea

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43

Chevreuil, Maelenn. "Phénomènes dynamiques d’auto-assemblage et de désassemblage dans des virus icosaédriques." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASS043.

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L’auto-assemblage et le désassemblage de la capside des virus, étapes critiques du cycle viral, est un sujet qui suscite beaucoup d’intérêt. Cependant, les mécanismes sous-jacents et, en particulier, les chemins dynamique d’assemblage et de désassemblage des capsides, vides ou pleines, des virus ne sont pas entièrement résolues. La diffusion des rayons X aux petits angles résolue en temps, combinée à la décomposition en valeur singulière, est une technique qui permet d’étudier des processus impliquant des espèces de taille nanométrique avec une résolution temporelle de l’ordre de la millisecon

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Guiras, Zouhour. "Contribution à l'optimisation des politiques de maintenance et l'analyse de risque dans la planification des opérations d’assemblage - désassemblage à deux niveaux." Thesis, Université de Lorraine, 2019. http://www.theses.fr/2019LORR0016/document.

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La réalité des marchés économiques impose des contraintes aux entreprises manufacturières qui sont de plus en plus difficiles à réaliser, comme la diversification des produits, l'amélioration de leur qualité, la réduction des coûts et la diminution des retards. Ces contraintes sont satisfaites par une meilleure organisation des systèmes de fabrication en utilisant les ressources techniques existantes. Notre présente thèse met l’accent sur deux contributions majeures, la première consiste à modéliser différents cas du système industriel (Système de production simple, système d’assemblage, systè

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Salma, Nunciada. "Transcriptional Regulation During Adipocyte Differentiation: A Role for SWI/SNF Chromatin Remodeling Enzymes: A Dissertation." eScholarship@UMMS, 2006. https://escholarship.umassmed.edu/gsbs_diss/50.

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Chromatin has a compact organization in which most DNA sequences are structurally inaccessible and functionally inactive. Reconfiguration of thechromatir required to activate transcription. This reconfiguration is achieved by the action of enzymes that covalently modify nucleosomal core histones, and by enzymes that disrupt histone-DNA interactions via ATP hydrolysis. TheSWI/SNF family of ATP-dependent chromatin remodeling enzymes has been implicated not only in gene activation but also in numerous cellular processes including differentiation, gene repression, cell cycle control, recombination

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Sinha, Manisha. "Recombinational Repair of a Chromosomal DNA Double Strand Break: A Dissertation." eScholarship@UMMS, 2009. https://escholarship.umassmed.edu/gsbs_diss/412.

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Repairing a chromosomal DNA double strand break is essential for survival and maintenance of genomic integrity of a eukaryotic organism. The eukaryotic cell has therefore evolved intricate mechanisms to counteract all sorts of genomic insults in the context of chromatin structure. Modulating chromatin structure has been crucial and integral in regulating a number of conserved repair processes along with other fundamental genomic processes like replication and transcription. The work in this dissertation has focused on understanding the role of chromatin remodeling enzymes in the repair of a ch

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Iacob, Robert-Eugen. "Modélisation cinématique des mobilités de composants pour des opérations d’assemblage et de désassemblage." Grenoble INPG, 2010. http://www.theses.fr/2010INPG0139.

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La conception assistée par ordinateur (CAO) a été l'un des domaines de recherche fondamental dans la conception automatisée pendant de nombreuses années. Les centres d'intérêt principaux sont les processus exigés pour concevoir différentes pièces, pour simuler leur comportement et pour les inspecter. Le module d’ensemble, qui adresse actuellement le produit entier, par comparaison ; est beaucoup moins étudié et un des processus peu compris dans la conception, sachant que presque tous les logiciels de CAO sont orientés vers les pièces seules. Afin d'offrir un outil pour l'analyse du modèle de p

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Young, Daniel W. "Regulation of Cell Growth and Differentiation within the Context of Nuclear Architecture by the Runx2 Transcription Factor: a Dissertation." eScholarship@UMMS, 2005. https://escholarship.umassmed.edu/gsbs_diss/19.

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The Runx family of transcription factors performs an essential role in animal development by controlling gene expression programs that mediate cell proliferation, growth and differentiation. The work described in this thesis is concerned with understanding mechanisms by which Runx proteins support this program of gene expression within the architectural context of the mammalian cell nucleus. Multiple aspects of nuclear architecture are influenced by Runx2 proteins including sequence-specific DNA binding at gene regulatory regions, organization of promoter chromatin structure, and higher-order

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Pennini, Meghan E. "Toll-like Receptor 2-dependent Inhibition of Interferon gamma Signaling by Mycobacterium tuberculosis." Connect to text online, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=case1152115234.

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Martins, Mateus Jose. "Projeto de um microcomputador de 8 bits para aplicações em pesquisa e ensino." Universidade de São Paulo, 1990. http://www.teses.usp.br/teses/disponiveis/54/54132/tde-11092007-110931/.

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O presente trabalho descreve o desenvolvimento de um microcomputador de 8 bits. O projeto inclui além dos circuitos básicos, lógica adicional para extender a memória contornando o limite normal de endereçamento. Um disco virtual uma interface em RAM e uma interface para \"Winchester\" foram desenvolvidas para extender a capacidade de armazenamento secundário e a velocidade de execução. Suporte para o coprocessador AM9511 é fornecido para freqüentes cálculos em ponto flutuante. Rotinas para operações básicas de E/,. manipulação da memória e \"Caching\" de disco, foram desenvolvidas para suport

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