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Bibliographies thématiques / Biliary epithelium / Thèses

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Thèses sur le sujet « Biliary epithelium »

Auteur : Grafiati

Publié le 9 mars 2023

Mis à jour le 31 juillet 2025

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1

Raven, Alexander Philip. "Impairing hepatocyte regeneration to determine the regenerative capacity of the biliary epithelium." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31177.

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Liver injury stimulates hepatocyte proliferation, regenerating the liver through self-replication. In cases where there is severe, repetitive, parenchymal damage, as seen in human chronic liver disease, hepatocyte mediated regeneration becomes impaired. In this setting it is currently unclear whether endogenous biliary epithelial cells can repopulate the hepatocyte compartment. This thesis therefore aimed to address this point by lineage tracing the main two liver epithelia populations on a background of impaired hepatocyte regeneration. To impair regeneration, an Itgb1 transgene was specifica

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2

SCIRPO, ROBERTO. "Activation of PPAR-gamma signaling as a novel target to limit nfkb-dependet in flammation in cystic fibrosis biliar epithelium." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2014. http://hdl.handle.net/10281/50586.

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Cystic fibrosis-associated liver disease (CFLD) is a chronic cholangiopathy that negatively impacts the quality of life and survival of patients with Cystic Fibrosis (CF). CF is a disease of secretory epithelia caused by genetically-determined defective function of CFTR (cystic fibrosis conductance regulator), a cAMP-activated Cl- channel that, in the liver, is uniquely expressed in the biliary epithelium. The pathogenesis of CFLD is thought to be related to the ductal cholestasis caused by the defective channel function of CFTR. However, a number of evidence indicate that, in association with

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3

Maxwell, John Perry. "Carcinoembryonic antigen (CEA) in the extrahepatic biliary tract : investigation of its function and localisation in benign and malignant epithelium." Thesis, Queen's University Belfast, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388237.

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4

Godoy, Torres Valeria. "Implicaciones del Purinoma en la Biología y Patología del Epitelio Biliar." Doctoral thesis, Universitat de Barcelona, 2013. http://hdl.handle.net/10803/133312.

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El purinoma está formado por la red de proteínas de membrana que median el efecto biológico final de la adenosina (Ado) extracelular y sus metabolitos (ATP, ADP y AMP). Sus componentes actúan de forma sinérgica y concertada para iniciar, mantener y terminar la señal purinérgica. Los elementos que conforman esta red son: los receptores purinérgicos P1 de adenosina, los receptores purinérgicos P2 para ATP y ADP, las ATP/ADPasas (nucleotidasas) responsables de la degradación extracelular del ATP y ADP, y los transportadores de nucleósidos equilibrativos (ENTs) y concentrativos (CNTs) encargados d

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5

Flynn, Diana Mary. "Isolation and characterisation of biliary epithelial cells in extrahepatic biliary atresia." Thesis, University of Birmingham, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433626.

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6

Chignard, Nicolas. "Bile Salts and Nuclear Receptors in Biliary Epithelial Cell Pathophysiology." Habilitation à diriger des recherches, Université Pierre et Marie Curie - Paris VI, 2012. http://tel.archives-ouvertes.fr/tel-00726374.

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The biliary epithelium is organized as a single layer of biliary epithelial cells (BECs) lining the biliary tree. BECs have three major biological functions: protection, secretion and proliferation. These functions may all be controlled by bile salts, the main constituents of bile. We therefore determined if human gallbladder-derived BECs exhibited bile salt transport activities that affect their secretory functions. We could show that the apical bile acid sodium- dependent transporter (ASBT) is expressed and functional in primary cultures of human BECs. Once transported inside BECs, bile salt

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7

Parola, Maurizio. "Biochemical studies on biliary epithelial cells isolated from rat liver." Thesis, Brunel University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.484102.

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8

Bratti, Maria Paz Leon. "Investigation of the immunogenicity of human intrahepatic biliary epithelial cells." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319181.

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9

Ayres, Reuben Christopher Simon. "In vitro investigation into the role of human intrahepatic biliary epithelial cells as targets in primary biliary cirrhosis." Thesis, University of Southampton, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296245.

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10

Brain, John George. "Investigation of injury and pharmacological modulation of biliary epithelial cells in ductopenic disease." Thesis, University of Newcastle upon Tyne, 2014. http://hdl.handle.net/10443/2437.

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Senescence and its associated secretory phenotype have been investigated in several vanishing bile duct syndromes. The current study evaluated the presence of senescent biliary epithelial cells (BEC) in acute cellular rejection of human liver allografts to ascertain whether senescent cells contribute to human disease progression in liver transplantation. There was a significant correlation between senescent BEC and grade of rejection. Furthermore there was a significant correlation between grade of rejection and BEC undergoing epithelial to mesenchymal transition (EMT). There was never any ove

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11

Liu, Chao. "Identification of liver stem-like cells in human derived intrahepatic biliary epithelial cells in vitro." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=967345642.

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12

Lam, Pak-yan Ian, and 林柏炘. "Secretin in biliary physiology: autocrine regulation on cholangiocyte proliferation and negative feedbackregulation on duodenal secretin expression via bile acids." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43572327.

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Lam, Pak-yan Ian. "Secretin in biliary physiology autocrine regulation on cholangiocyte proliferation and negative feedback regulation on duodenal secretin expression via bile acids /." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43572327.

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14

Russell, Clare Louise. "The functional significance of CD40 expression on human biliary epithelial cells and intrahepatic endothelial cells : implications for its regulation of human liver inflammatory responses." Thesis, University of Birmingham, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403910.

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15

Caenen, Chloe. "Implication des protéines à domaine B9 dans la tubulogenèse biliaire." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASL095.

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Le cil primaire est un organite essentiel à la transduction des principales voies de signalisation développementales dans la plupart des cellules de mammifères. Les protéines ciliaires à domaine B9, retrouvées à la zone de transition (ZT) du cil primaire, jouent un rôle dans la barrière de diffusion, régulant le passage des protéines dans le cil. Leurs mutations induisent des ciliopathies ayant un large spectre de symptômes, dont certains sont liés à la fonction de ces protéines dans les signalisations ciliaires Hedgehog et Wingless. Même si ces protéines à domaine B9 sont connues pour être in

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16

Liu, Chinsu, and 劉君恕. "Studies on the Expression of Antigens of Bile Canaliculi and Bile Ductule Epithelia of Livers in Biliary Atresia Using monoclonal Antibodies-Discussion of the Prognosis and Pathogenesis in Biliary Atresia." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/05929494185247410938.

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博士<br>國立陽明大學<br>臨床醫學研究所<br>89<br>Biliary atresia (BA) is the most puzzled disease in the field of pediatric surgery. Clinical manifestations are neonatal jaundice, direct hyperbilirubinemia, passage of clay stool and obliteration of extrahepatic bile duct. This disease was incurable until Dr. Kasai, a Japanese surgeon, reported his portoenterostomy in 1957, which was the procedure of excision of extrahepatic fibrotic bile duct to liver hilum and roux-en-y portojejunostomy. During the past four decades, many investigations have been made to figure out the etiologies of BA and the predictors for

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17

Liu, Chao [Verfasser]. "Identification of liver stem-like cells in human derived intrahepatic biliary epithelial cells in vitro / vorgelegt von Chao Liu." 2002. http://d-nb.info/967345642/34.

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