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1

Yang, Shuang, and Wan Nur Tasnim Wan Hussin. "Research on Older Adults’ Willingness to Enroll in Health Care Services based on Andersen Behavioral Model." Academic Journal of Management and Social Sciences 5, no. 1 (2023): 23–26. http://dx.doi.org/10.54097/ajmss.v5i1.13902.

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Ageing has increasingly become a severe social problem nowadays, resulting in burden for both whole society and each family unit. Jiangsu is a typical aging province in China with dramatically increasing aging population. This paper analyzed Andersen behavioral model theoretically and empirically, and made an overview about older adults’ healthcare services utilization behavior from three aspects, namely, predisposing characteristics, enabling resources, and need factors. This paper revealed that it is significant to apply Andersen behavioral model in older adults’ healthcare services utilizat
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Brown, Suzanne, David E. Biegel, and Elizabeth M. Tracy. "Likelihood of Asking for Help in Caregivers of Women With Substance Use or Co-Occurring Substance Use and Mental Disorders." Care Management Journals 12, no. 3 (2011): 94–100. http://dx.doi.org/10.1891/1521-0987.12.3.94.

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Family members are important to the well-being of their relatives with substance use disorders or co-occurring substance use and mental disorders. Many caregivers experience high levels of burden, negatively impacting their capacity to provide support to their ill family member. The Andersen health care utilization model (Andersen & Newman, 1973, 2005) was used to identify the impact of predisposing, enabling, and need factors hypothesized to predict caregivers’ likelihood of asking for help and support with their caregiving role. The sample include 82 women recruited from outpatient or in
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Rezazadeh, Saman, Jiqing Guo, Henry J. Duff, Raechel A. Ferrier, and Brenda Gerull. "Reversible Dilated Cardiomyopathy Caused by a High Burden of Ventricular Arrhythmias in Andersen-Tawil Syndrome." Canadian Journal of Cardiology 32, no. 12 (2016): 1576.e15–1576.e18. http://dx.doi.org/10.1016/j.cjca.2016.07.587.

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Bischof, Günter. "Heinrich Wildner Tagebücher 1938–1944: “Heute geht es gegen die Juden, morgen kann es gegen die anderen gehen . . .” ed. by Gertrude Enderle-Burcel (review)." Journal of Austrian Studies 57, no. 2 (2024): 113–26. http://dx.doi.org/10.1353/oas.2024.a929391.

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Sun, Qian, Nan Lu, Nan Jiang, and Vivian W. Q. Lou. "Intention to use respite services among informal care-givers of frail older adults in China: the role of care needs change." Ageing and Society 41, no. 1 (2020): 101–20. http://dx.doi.org/10.1017/s0144686x20000628.

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AbstractPopulation ageing in China calls for evidence-based solutions, especially in terms of fulfilling long-term care needs among frail older adults. Respite services are identified as effective resources for alleviating care-giver burden and promoting the wellbeing of both older adults and their family care-givers. However, respite care is often under-used in China. This research aimed to examine factors associated with intention to use respite services among informal care-givers in Shanghai, mainland China. This study was part of the Longitudinal Study on Family Caregivers for Frail Older
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Chang, Sujie. "Factors Influencing the Transition Intentions of LTCI Home Benefit Recipients to Facilities/Hospitals." Korean Association of Health and Medical Sociology 67 (December 31, 2024): 5–33. https://doi.org/10.37243/kahms.2024.67.5.

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The goal of elderly care in our society is Aging in Place (AIP). In line with this, the Long-Term Care Insurance (LTCI) system has strengthened home care services. Despite these efforts, many individuals still transition from home care to facility-based services. This study investigates the factors influencing LTCI home benefit recipients' intentions to transition to facility-based services. It aims to distinguish between transitions from home to nursing facilities and from home to long-term care hospitals to identify factors that promote or hinder AIP and derive practical implications for eld
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Kilian, Jürgen. "Krieg auf Kosten anderer. Wehrmachtfinanzierung in Griechenland während des Zweiten Weltkriegs / War at the Expence of Others Financing the „Wehrmacht“ in Greece during the Second World War." Südost-Forschungen 73, no. 1 (2014): 38–59. http://dx.doi.org/10.1515/sofo-2014-0104.

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Abstract After Greece had been conquered by the troops of the Axis Powers in spring 1941, they installed a rule of occupation existing until october 1944. The Government in Athens had to finance this occupation by making payments in advance and besides, making a forced credit available. This method led to an exorbitant overloading of the Greek economy and to a galloping inflation. The German Tax and Finance Ministry played an important, yet hardly noticed role as to the concrete implementation of the monetary exploitation. Almost unknown documents throw a light on the financing of the German W
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Wiedemann, Andreas, Vedat Dündar, Melanie Heese, et al. "Unerwünschte Arzneimittelwirkungen am Harntrakt – der Wittener Harntrakt-Nebenwirkungs-Score." Aktuelle Urologie 52, no. 05 (2021): 481–89. http://dx.doi.org/10.1055/a-1352-9370.

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ZusammenfassungObwohl der Harntrakt mit Restharnbildung, Harnverhaltung, Pollakisurie, Polyurie, Nykturie, Detrusorstimulation, Detrusorhemmung, Hämaturie, Dysurie und anderen Erscheinungen häufig den Schauplatz unerwünschter Arzneimittelwirkungen darstellt, fehlt es an einer Gesamtübersicht an Substanzen, die eine solche Harntraktnebenwirkung auslösen können und eine entsprechende Bewertung. Vorhandene Listen „potenziell inadäquater Medikation“ fokussieren entweder auf eine pharmakologische Gruppe von Nebenwirkungen („anticholinergic burden score“), eine Gruppe von Medikamenten bestimmter Ind
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Snijders, Tjamke. "Burcht Pranger, God (1000–1300) en andere essays over literaire aspecten van het christendom [Middeleeuwse Studies en Bronnen 142]. Verloren, Hilversum 2013, 192 pp. ISBN 9789087043223. €25." Church History and Religious Culture 94, no. 1 (2014): 90–91. http://dx.doi.org/10.1163/18712428-09401009.

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Du, Jinglin, Xue Yang, Mingsheng Chen, and Zhonghua Wang. "Socioeconomic determinants of out-of-pocket pharmaceutical expenditure among middle-aged and elderly adults based on the China Health and Retirement Longitudinal Survey." BMJ Open 9, no. 7 (2019): e024936. http://dx.doi.org/10.1136/bmjopen-2018-024936.

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ObjectiveOut-of-pocket pharmaceutical expenditure (OOPPE) is a considerable burden for middle-aged and elderly adults due to their high prevalence of diseases, insufficient income and absence of medical insurance in China. The objective of this study was to assess the determinants of OOPPE among Chinese middle-aged and elderly adults.MethodsThis is a cross-sectional study based on the China Health and Retirement Longitudinal Survey conducted in 2015. The Andersen behavioural health model was used to select the factors. Binary multivariable logistic and generalised linear regressions were both
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Younis, Arwa, Sanah Ali, Eileen Hsich, et al. "Arrhythmia and Survival Outcomes Among Black Patients and White Patients With a Primary Prevention Defibrillator." Circulation 148, no. 3 (2023): 241–52. http://dx.doi.org/10.1161/circulationaha.123.065367.

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BACKGROUND: Black Americans have a higher risk of nonischemic cardiomyopathy (NICM) than White Americans. We aimed to evaluate differences in the risk of tachyarrhythmias among patients with an implantable cardioverter-defibrillator (ICD). METHODS: The study population comprised 3895 ICD recipients in the United States enrolled in primary prevention ICD trials. Outcome measures included ventricular tachyarrhythmia (VTA), atrial tachyarrhythmia (ATA), ICD therapies, VTA burden (using Andersen-Gill recurrent event analysis), death, and the predicted benefit of the ICD. All events were adjudicate
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Effiong, Ben Victor, and Oboma Lawrence Adhowhoarie. "Predictors of antenatal care services utilization by pregnant women in a selected Akwa Ibom state community, Nigeria." American Journal of Social Sciences and Humanities 8, no. 2 (2023): 173–86. http://dx.doi.org/10.55284/ajssh.v8i2.913.

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In Nigeria, the burden and incidence rate of maternal mortality significantly affects the achievement of the Sustainable Development Goal 3. The study was designed to investigate the factors and trends of Antenatal Care Services Utilization by Pregnant Women in Anua Community Akwa Ibom State, Nigeria. The assumptions of Andersen Behavioural Model of Health Services and Antonovsky Theory of Social Class were adopted to explain the use of antenatal care services. A combined survey was conducted to obtain primary data from 264 women between the ages of 15 and 49 selected as respondents through sn
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Nonoyama, Mika L., Douglas A. McKim, Jeremy Road, et al. "Healthcare utilisation and costs of home mechanical ventilation." Thorax 73, no. 7 (2018): 644–51. http://dx.doi.org/10.1136/thoraxjnl-2017-211138.

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BackgroundIndividuals using home mechanical ventilation (HMV) frequently choose to live at home for quality of life, despite financial burden. Previous studies of healthcare utilisation and costs do not consider public and private expenditures, including caregiver time.ObjectivesTo determine public and private healthcare utilisation and costs for HMV users living at home in two Canadian provinces, and examine factors associated with higher costs.MethodsLongitudinal, prospective observational cost analysis study (April 2012 to August 2015) collecting data on public and private (out-of-pocket, t
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Sriram, Shyamkumar, Arun Daniel Jayakumar, Pavan Kumar Gollapalli, and Swetha Chadrasekar. "Demand-side barriers and economic burden in accessing Human Papillomavirus screening for cervical cancer prevention in rural India: Evidence from a cross-sectional study." F1000Research 13 (June 13, 2024): 630. http://dx.doi.org/10.12688/f1000research.150361.1.

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Introduction Cervical cancer is a significant global health concern, especially in low- and middle-income countries with limited access to preventive healthcare. India’s vast rural population amplifies the challenge, demanding immediate action. Despite advancements, cervical cancer remains prevalent among underserved rural communities, hindered by barriers to Human Papillomavirus (HPV) screening uptake, including socioeconomic and financial constraints. This study aims to evaluate the economic challenges encountered by rural women when accessing HPV screening. Methods A cross-sectional survey
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Sriram, Shyamkumar, Arun Daniel Jayakumar, Pavan Kumar Gollapalli, and Swetha Chandrasekar. "Demand-side barriers and economic burden in accessing Human Papillomavirus screening for cervical cancer prevention in rural India: Evidence from a cross-sectional study." F1000Research 13 (February 17, 2025): 630. https://doi.org/10.12688/f1000research.150361.2.

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Introduction Cervical cancer is a significant global health concern, especially in low- and middle-income countries with limited access to preventive healthcare. India’s vast rural population amplifies the challenge, demanding immediate action. Despite advancements, cervical cancer remains prevalent among underserved rural communities, hindered by barriers to Human Papillomavirus (HPV) screening uptake, including socioeconomic and financial constraints. This study aims to evaluate the economic challenges encountered by rural women when accessing HPV screening. Methods A cross-sectional survey
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Bischoff, Werner, David Ornelles, Lauren Ivey, and Bill Payne. "Assessing alternatives to HEPA air purification requirements to reduce viral pathogen transmission in healthcare HVAC systems." Antimicrobial Stewardship & Healthcare Epidemiology 2, S1 (2022): s85. http://dx.doi.org/10.1017/ash.2022.217.

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Background: High-efficiency particulate air (HEPA) filters are currently recommended when using recirculated air to eliminate the risk of pathogen transmission such as SARS-CoV-2 from one patient care area to the next. We tested the efficacy of lower-grade air filters in eliminating airborne virus transmission. Methods: We conducted an experiment in 2 adjacent exam rooms in an unoccupied hospital emergency unit. The HVAC system contained a 15,000-cubic-feet-per-minute rooftop air handler. All outside air and exhaust dampers were closed during the trial (full air recirculation). We conducted ex
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Cornet, A., J. Andersen, F. Marchiori, et al. "POS0571 ASSOCIATION BETWEEN DIAGNOSIS DELAY AND DISEASE ACTIVITY WITH BURDEN OF THE DISEASE IN 4150 EUROPEAN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 554.1–554. http://dx.doi.org/10.1136/annrheumdis-2023-eular.1250.

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BackgroundDespite significant improvements in diagnosis delay and treatment strategies, the burden of Systemic Lupus Erythematosus (SLE) remains high.ObjectivesThe objective of the study was to assess the association between diagnosis delay, disease activity and burden on daily life (BoDL) in a large sample of European patients with SLE.MethodsIn May 2020, Lupus Europe, the European umbrella patient association for SLE, conducted a multilingual anonymous online cross-sectional study to individuals with a self-reported physician’s diagnosis of SLE living in Europe. The BoDL score was computed u
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Zeng, Yanbing, Weiqian Xu, and Xiaomeng Tao. "What factors are associated with utilisation of health services for the poor elderly? Evidence from a nationally representative longitudinal survey in China." BMJ Open 12, no. 6 (2022): e059758. http://dx.doi.org/10.1136/bmjopen-2021-059758.

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ObjectivesTo investigate the status and factors of healthcare service utilisation among the poor elderly in China.MethodsWe selected the poor elderly from the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2015. The main outcome measures include utilisation indicators for the probability and costs of outpatient/inpatient services. Based on modified Andersen behaviour model, a two-part model is designed to analyse the factors of the health service utilisation of the poor elderly.ResultsThe visit rate of outpatient services increased from 15.05% in 2011 to 21.26% in 2015, a
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Levison, Julie H., Lourdes García-Fragoso, Ines E. García García, et al. "1139. Adherence to Zika virus-related Pediatric Follow-up Care in Puerto Rico." Open Forum Infectious Diseases 7, Supplement_1 (2020): S598. http://dx.doi.org/10.1093/ofid/ofaa439.1325.

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Abstract Background Over three thousand children in Puerto Rico were potentially exposed to Zika virus infection during pregnancy during the 2016 Zika virus epidemic. This congenital exposure is an established risk factor for birth defects and neurodevelopmental abnormalities, which may appear after birth. Puerto Rico guidelines require consistent pediatric monitoring for early identification and intervention of children up to age five. Methods Our objective was to assess factors that influence caregiver adherence to Zika-related follow-up pediatric services in Puerto Rico. We conducted qualit
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Siekmann, Helmut. "The Burden of an Ageing Society as a Public Debt: The Perspective of the German Constitutional Law and the Law of the European Union." European Public Law 13, Issue 3 (2007): 489–518. http://dx.doi.org/10.54648/euro2007028.

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This article is based on the assumption that the financial burden of an ageing society can be considered as an ‘implicit’ public debt. The future claims (‘prospective entitlements’) to unfunded public pension systems will result in severe financial strains for public finances because of the demographic developments in Germany and other industrialized nations. A closer analysis of the German (federal) constitution reveals that there are almost no provisions to handle the potential dangers from this foreseeable development. The rules on explicit public debt and the accounting requirements for th
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Hradová, Jana. "The Nature of Disease as a Pastoral Key. A Theological Reflection." European Journal of Theology 28, no. 2 (2020): 154–60. http://dx.doi.org/10.5117/ejt2019.2.007.hrad.

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SummaryDo disease and suffering, in their deepest essence, represent blessings? Are they allowed or even intended by God? Are they, primarily, a test of faith and a cryptogram which needs to be decoded and responded to, or does their presence rather obscure the true nature of salvation? Specific ways of thinking about diseases, such as those of Smolík, MacNutt, Grün, Dufner and others, substantially influence the objectives and methods of pastoral work. In addition to some relevant biblical texts, this article deals with considerations of how the burden of suffering can be shared with other pe
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S Masinde, Millicent, Joshua K Kayima, Wanyoike J Gichuhi, Eunice C Cheserem, Orora I Maranga, and Samuel K Kabinga. "Infection with high-risk genotypes of human papillomavirus and cervical cytological findings among kidney transplant recipients in Kenya: a single centre experience." African Health Sciences 22, no. 2 (2022): 88–96. http://dx.doi.org/10.4314/ahs.v22i2.11.

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Background: High-risk human papillomavirus (hrHPV) infection is linked with uterine cervix premalignant lesions and invasive carcinomaof the uterine cervix.
 Methods: Descriptive cross sectional study carried out among female kidney transplant (KTx) recipients in Kenyatta National Hospital, Nairobi-Kenya. We studied the risk factors for acquisition of hrHPV, examined cervical cytology and assayed for 14 hrHPV DNA using Cervista® HPV HR test and Cervista® MTA (Hologic®) automated platforms.
 Results: The 14-hrHPV genotypes assayed were 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 6
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Andersen, Stacy, and Patricia Heyn. "Alzheimer’s Disease Research and Outreach in the New Normal: Transitioning to the Virtual World." Innovation in Aging 5, Supplement_1 (2021): 135–36. http://dx.doi.org/10.1093/geroni/igab046.525.

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Abstract Following disruptions to research, clinical trials, and support for individuals with Alzheimer’s disease and related dementias (ADRD), 2020 taught us important lessons about the need for creativity, flexibility, and resourcefulness during an urgent and global public health crisis. The COVID-19 pandemic showed that we have knowledge and technology that can be rapidly implemented, adopted, and utilized by many sectors to allow the continued care and research of our older adult population with ADRD. Thus, this symposium will address virtual methods that are transforming ADRD research and
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Shrestha, Srijana, Amber Amspoker, Tracy L. Evans, et al. "PREDICTORS OF MEDICAL, SOCIAL SERVICE, AND MENTAL HEALTH USE AMONG PEOPLE WITH DEMENTIA AND THEIR CAREGIVERS." Innovation in Aging 3, Supplement_1 (2019): S933—S934. http://dx.doi.org/10.1093/geroni/igz038.3396.

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Abstract People with Alzheimer’s disease use more medical services (Eaker et al., 2002) and are admitted to inpatient facilities at higher rates (Zhu et al., 2015) than normal controls. In addition, social services provide support for caregivers and are associated with positive outcomes for care-recipients and their caregivers (Neville, Beattle, Fielding, & MacAndrew, 2014). Despite high level of need, utilization of mental health services and social agencies for caregiver support remains low (Goodarzi, Mele, Roberts & Holroyd-Leduc, 2017; Weber, Pirraglia & Kunik, 2011). Following
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Torres, Juliana L., Silvia L. A. da Silva, Fabiane R. Ferreira, Liliane P. S. Mendes, and Luciana A. Machado. "Chronic pain is associated with increased health care use among community-dwelling older adults in Brazil: the Pain in the Elderly (PAINEL) Study." Family Practice 36, no. 5 (2018): 594–99. http://dx.doi.org/10.1093/fampra/cmy123.

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Abstract Background Chronic pain is known to increase health care use in high-income countries, but in Brazil, little is known. Objective To investigate the association between chronic pain and health care use among Brazilian older adults and explore the relationship between pain severity and health care use. Methods This cross-sectional study was derived from the population-based study Frailty in Brazilian Older People-FIBRA. Chronic pain, pain intensity and pain-related disability were assessed through additional telephone interviews. Health care use was measured by the number of doctor visi
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Choi, Hyojin, Kristin Litzelman, Autumn Harnish, and Maija Reblin. "RESOURCE UTILIZATION AMONG FAMILY CAREGIVERS: INDIVIDUAL AND NEIGHBORHOOD CHARACTERISTICS." Innovation in Aging 6, Supplement_1 (2022): 355. http://dx.doi.org/10.1093/geroni/igac059.1404.

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Abstract Resources in the community play a pivotal role in increasing well-being of both care recipients and caregivers and ensuring equitable access to needed resources is a crucial priority for policy and practice. Drawing on the Andersen Behavioral Model, this study explored the longitudinal relationship between individual and neighborhood factors and social resource utilization (i.e., paid caregivers, respite care, support group, training, financial help, or transportation) among family caregivers. Unpaid family caregivers for community-dwelling older adults were identified using data from
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Knabe, Andreas, and Joachim Weimann. "Die Deutschlandrente: Wirksamkeit und Legitimität eines Nudges." Vierteljahrshefte zur Wirtschaftsforschung 87, no. 2 (2018): 33–46. http://dx.doi.org/10.3790/vjh.87.2.33.

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Zusammenfassung: Der demografische Wandel wird die umlagefinanzierte gesetzliche Rentenversicherung in den kommenden Jahrzehnten stark belasten. Bisherige Rentenreformen zielten daher darauf ab, durch steuerliche Förderung die zusätzliche kapitalgedeckte Altersvorsorge zu stärken. Diese Möglichkeit wird aber bisher nur unzureichend in Anspruch genommen. Wir machen dafür vor allem zwei Ursachen verantwortlich. Zum einen ist gegenwärtig die private Altersvorsorge nach dem „Opt-In“-Prinzip organisiert. Nur derjenige sorgt zusätzlich vor, der sich aktiv dafür entscheidet. Zum anderen weisen viele
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Guilatco, Angelo Jose, Marta Diaz-del-Castillo, Gabriel Alvares Borges, et al. "Abstract 2958: Melphalan-treated multiple myeloma cells exhibit a senescent-like dormancy phenotype." Cancer Research 84, no. 6_Supplement (2024): 2958. http://dx.doi.org/10.1158/1538-7445.am2024-2958.

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Abstract Multiple myeloma (MM) is an incurable plasma cell (PC) cancer in which all patients are expected to relapse. Cytotoxic agents such as high-dose melphalan (HDM), which is used as a myeloablative agent prior to autologous stem cell transplant (ASCT) in MM, drive therapy-induced senescence (TIS) in non-cancerous tissues. We hypothesized that HDM similarly activates TIS pathways in surviving MM cells and this response may correlate with patient outcomes post-ASCT. To test this, we developed an in vitro model in which 5TGM1 mouse MM cells are cultured with 10uM melphalan (HDM) or vehicle (
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Henriksen, Tenna V., Christina Demuth, Amanda Frydendahl, et al. "Abstract 2306: Potential clinical utility of circulating tumor DNA detected by digital PCR in a nationwide Danish cohort of high-risk colorectal cancer patients." Cancer Research 83, no. 7_Supplement (2023): 2306. http://dx.doi.org/10.1158/1538-7445.am2023-2306.

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Abstract Introduction: Increasingly, circulating tumor DNA (ctDNA) is proposed as a tool for minimal residual disease (MRD) assessment, with the potential to guide postoperative treatment decisions. Low ctDNA levels immediately after surgery necessitate extremely sensitive detection methods. Additionally, for potential clinical implementation, detection methods should ideally feature short turnaround times (TATs) and low analysis costs. Compared to sequencing-based detection methods, digital PCR is low-cost, and features TATs of less than a day. Consequently, digital PCR is a good candidate fo
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Pérez Chacón, Gladymar, Parveen Fathima, Mark Jones, et al. "Pertussis immunisation in infancy and atopic outcomes: A protocol for a population-based cohort study using linked administrative data." PLOS ONE 16, no. 12 (2021): e0260388. http://dx.doi.org/10.1371/journal.pone.0260388.

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Introduction The burden of IgE-mediated food allergy in Australian born children is reported to be among the highest globally. This illness shares risk factors and frequently coexists with asthma, one of the most common noncommunicable diseases of childhood. Findings from a case-control study suggest that compared to immunisation with acellular pertussis vaccine, early priming of infants with whole-cell pertussis vaccine may be associated with a lower risk of subsequent IgE-mediated food allergy. If whole-cell vaccination is protective of food allergy and other atopic diseases, especially if p
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Sonko, Ismaila, Min-Huey Chung, Wen-Hsuan Hou, Wei-Ti Chen, and Pi-Chen Chang. "Predictors of HIV testing among youth aged 15–24 years in The Gambia." PLOS ONE 17, no. 2 (2022): e0263720. http://dx.doi.org/10.1371/journal.pone.0263720.

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Background Worldwide, an estimated 38.0 million people lived with the human immunodeficiency virus in 2019, and 3.4 million young people aged 15~24 years were living with HIV. Sub-Saharan Africa carries a significant HIV burden with West and Central Africa most affected with HIV. Among the young people living with HIV in West and Central Africa, an estimated 810,000 were aged 15~24 years. This study aimed to assess predictors that influence the uptake of HIV testing among youth aged 15~24 years in The Gambia. Methods The 2013 Gambia Demographic and Health Survey data for youth aged 15~24 years
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West, Ryan, John W. Thomas, Elaine Smith, et al. "Efficacy of screening and treatment of breast cancer patients reporting high level of distress." Journal of Clinical Oncology 33, no. 28_suppl (2015): 101. http://dx.doi.org/10.1200/jco.2015.33.28_suppl.101.

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101 Background: Cancer patients (pts) are burdened by symptoms related to the disease itself or to the toxicities of treatment. The ASCO clinical oncology guideline adaptation recommends all health care providers routinely screen for the presence of emotional distress and specifically symptoms of anxiety from the point of diagnosis onward [Andersen BL, 2014].At Cancer Treatment Centers of America (CTCA) we perform screening assessments using a Symptom Inventory Tool (SIT) composed of 27 questions. Pts with moderate and severe levels of anxiety are evaluated by the Integrative Resource Assessme
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呂美卿, 呂美卿, 劉翠瑤 IMei-Ching Liu та 洪啓峯 Tsui-Yao Liu. "影響居家護理個案之照顧者對居家醫療整合照護使用意願之探討-以北部某區域醫院附設某居家護理所為例". 輔仁醫學期刊 21, № 2 (2023): 001–12. http://dx.doi.org/10.53106/181020932023062102001.

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<p>目的:探討北部某區域醫院附設居家護理所之個案,影響參加居家醫療服務的相關因素。方法:橫斷性研究設計,使用Andersen所提出醫療利用性模式為架構,於2021年9至10月對居家護理個案主要決策之照顧者共91位進行結構式問卷,內容為:被照顧者及照顧者基本資料、居家醫療整合照護認知、照顧者知覺量表、照顧者負荷量表。統計方法為描述性統計、t檢定、Anova檢定、卡方檢定、皮爾森積差相關分析與多元邏輯斯迴歸分析。結果:不同的固定就醫場所與參加居家醫療呈統計上顯著差異。照顧者壓力生理負荷對壓力心理與社會負荷有高度正相關,壓力財務負荷對壓力生理、心理與社會負荷有中度正相關,壓力心理負荷與壓力社會負荷有高度正相關。影響居家醫療整合照護之預測因子為固定就醫場所。結論:本研究結果促使因素中個案有固定就醫場所,參加居家醫療整合照護服務達顯著相關。有無固定的就醫場所是消費者對組織易接近或熟悉的地方,常被用來預測醫療服務利用度的高低,有固定就醫地點、醫師,能有連續性及協調性的照護。</p> <p> </p><p>Objective: To investigate a case of a home care center attached to regional hos-pital in northern Taiwan, a
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Roderick, Justine, Scott Boiko, Courtney L. Andersen, et al. "AZD4573 Effectively Induces Apoptosis in r/r MCL As a Monotherapy or in Combination with Acalabrutinib." Blood 138, Supplement 1 (2021): 2255. http://dx.doi.org/10.1182/blood-2021-151725.

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Abstract Mantle cell lymphoma (MCL) is an aggressive form of NHL where frequent relapse following standard therapies remains a serious concern, even for promising new treatments such as combinations of a BTK inhibitor with the selective Bcl2 inhibitor venetoclax. Previous studies have also shown that MCL cells develop resistance through tumor microenvironment interactions that increase levels of Mcl1, BclxL, and/or Bfl1. Given the ability of CDK9 inhibition to deplete Mcl1 and Bfl1 (Boiko et al 2021), we explored the potential of clinical-stage inhibitor AZD4573 to induce apoptosis in MCL cell
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Ladetto, Marco, Simone Ferrero, Daniela Drandi, et al. "LONG-TERM RESULTS of the GIMEMA VTD Consolidation TRIAL In Autografted MULTIPLE Myeloma PATIENTS (VEL-03-096): IMPACT of Minimal RESIDUAL DISEASE Detection by REAL Time Quantitative PCR On LATE Recurrences and Overall SURVIVAL." Blood 118, no. 21 (2011): 827. http://dx.doi.org/10.1182/blood.v118.21.827.827.

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Abstract Abstract 827 Background and aims: We have recently shown that a consolidation therapy with bortezomib/thalidomide/dexamethasone (VTD) in multiple myeloma (MM) patients responding to autologous transplantation (ASCT) induces major tumor shrinking assessed by real time-quantitative (RQ)-PCR. Moreover we found that low levels of minimal residual disease (MRD) associated to a better progression-free survival (PFS) [GIMEMA VEL-03-096 trial, EudraCT Number 2004-000531-28: Ladetto et al, J Clin Oncol 2010]. We here present the updated results of this study at a median follow-up of 65 months.
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Kwok, Jaime Kirsten, Kevin Martell, Michael Sia, et al. "Local prostate radiotherapy in metastatic prostate cancer and symptomatic local events." Journal of Clinical Oncology 39, no. 6_suppl (2021): 111. http://dx.doi.org/10.1200/jco.2021.39.6_suppl.111.

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111 Background: Local prostate radiotherapy (LPRT) is associated with improved overall survival in patients with low metastatic burden (MB) and is now standard of care. However, the role of LPRT in reducing symptomatic local events (SLE) in metastatic prostate cancer (MPC) remains unclear and requires long-term follow-up. The purpose of this study was two-fold: i) identify the risk factors associated with SLE, and ii) evaluate the association between LPRT and SLE in MPC. Methods: We conducted a retrospective, population-based cohort study of patients diagnosed with initial MPC between 2005 and
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Andersen, Courtney L., Amanda L. Christie, Alan Rosen, et al. "Identification of Novel Combination Therapies Active in BCL2 Inhibitor-Resistant Patient-Derived AML Models." Blood 134, Supplement_1 (2019): 1273. http://dx.doi.org/10.1182/blood-2019-129475.

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Acute myeloid leukemia (AML) is an aggressive, heterogeneous malignancy. AML patients whose disease relapses on chemotherapy or are unfit for aggressive induction regimens have limited therapeutic options. Many patients benefit from the combination of venetoclax (BCL2i) and a hypomethylating agent (HMA) but this regimen is rarely curative. The addition of novel agents could provide improved benefit for relapsed/refractory patients. To identify such regimens, we screened a panel of 10 AML cell lines with combinations of venetoclax and novel targeted agents. The agents used spanned multiple mech
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George, Goldy C., Clark R. Andersen, Xiaohui Tang, John A. Livingston, Michael E. Roth, and Michelle A. Hildebrandt. "Abstract 1997: Health-related quality of life at diagnosis in survivors of adolescent and young adult cancer." Cancer Research 82, no. 12_Supplement (2022): 1997. http://dx.doi.org/10.1158/1538-7445.am2022-1997.

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Abstract Purpose: Data are lacking on the distribution, factors associated with, and long-term impact of diminished health-related quality of life (HRQoL) at diagnosis in adolescent and young adult (AYA) cancer survivors (≥2 years post cancer diagnosis). Our goal was to fill this gap in knowledge. Methods: A cohort of AYA (15y - 39y) cancer patients treated at MD Anderson between 2000-2016 who had survived at least 2 y was identified from our Institutional Tumor Registry. HRQoL was assessed at diagnosis with the SF12v1 questionnaire. Demographic and behavioral risk factors, tumor type, and vit
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Lowman, Geoffrey Marc, Dinesh Cyanam, Emily Norris, et al. "Abstract 232: Fully automated comprehensive genomic profiling for detection of cancer variants, gene fusions, and complex oncology endpoints." Cancer Research 83, no. 7_Supplement (2023): 232. http://dx.doi.org/10.1158/1538-7445.am2023-232.

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Abstract Introduction: We present the comprehensive genomic profiling performance of the Ion Torrent Genexus system using the Oncomine Comprehensive Assay Plus (OCA Plus), a 500+ gene targeted AmpliSeq-based oncology research panel that evaluates DNA variants (including copy number alterations), RNA fusions, and key oncology research endpoints including tumor mutational burden (TMB), microsatellite instability (MSI), and homologous recombination repair deficiency (HRD) via characterization of genomic instability by the newly introduced Genomic Instability Metric (GIM). Methods: The Ion Torrent
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Moore, Simon C., Mohammed Fasihul Alam, David Cohen, et al. "All-Wales Licensed Premises Intervention (AWLPI): a randomised controlled trial of an intervention to reduce alcohol-related violence." Public Health Research 3, no. 10 (2015): 1–152. http://dx.doi.org/10.3310/phr03100.

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BackgroundViolence in and around premises licensed for the on-site sale and consumption of alcohol continues to burden the NHS with assault-related injuries.Trial designA randomised controlled trial with licensed premises as the unit of allocation, with additional process and cost-effectiveness evaluations.MethodsPremises were eligible (n = 837) if they were licensed for on-site sale and consumption of alcohol, were within 1 of the 22 local authorities (LAs) in Wales and had previously experienced violence. Data were analysed using Andersen–Gill recurrent event models in an intention-to-treat
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Matos, Jefferson David Melo de, Leonardo Jiro Nomura Nakano, André Guimarães Rodrigues, et al. "Orofacial clefts: treatment based on a multidisciplinary approach." ARCHIVES OF HEALTH INVESTIGATION 9, no. 5 (2020): 468–73. http://dx.doi.org/10.21270/archi.v9i5.4804.

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Objective: The present study aims to expose through a literature review the cleft lip and/or cleft palate (CL/CP) and its treatment in a multidisciplinary approach. Methodology: This literature review was conducted by the leading health databases: Pubmed (https://www.ncbi.nlm.nih.gov/pubmed). The keywords for the textual search were: Cleft Lip; Cleft Palate; Dental Staff; Classification; Embryology. The inclusion criteria were: literature on the subject under study, literature of the last years, english language, laboratory and clinical studies and systematic review. Literature Review: Fissure
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Knight, Robert. "Heinrich Wildner Tagebücher 1938–1944 ("Heute geht es gegen die Juden, morgen kann es gegen die anderen gehen…") ed. by Gertrude Enderle-Burcel, and: Das Tagebuch von Heinrich Wildner 1945 ("Ich bestelle Sie hiemit zur Leitung des Außenamtes,…") ed. by Roman Eccher et al., and: Das Tagebuch von Heinrich Wildner 1946 ("...freilich werden wir im neuen Jahr noch nicht frei werden...") ed. by Roman Eccher et al., and: Das Tagebuch von Heinrich Wildner 1947 ("Man ist noch immer nervös. Wir sind sehr scharf bewacht") ed. by Elisabeth Gmoser et al., and: Das Tagebuch von Heinrich Wildner 1948 ("Es regiert der Planet Pallawatsch") ed. by Ernst Aichinger et al., and: Das Tagebuch von Heinrich Wildner 1949 ("Wie soll das weiter gehen?") ed. by Josef Litschauer et al. (review)." Austrian Studies 31, no. 1 (2023): 218–21. http://dx.doi.org/10.1353/aus.2023.a919435.

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Mungo, Chemtai. "Abstract NG13: Feasibility of topical self-administered therapies to improve cervical precancer treatment outcomes among women living with HIV in low-and middle-income countries." Cancer Research 83, no. 7_Supplement (2023): NG13. http://dx.doi.org/10.1158/1538-7445.am2023-ng13.

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Abstract Global trends of invasive cervical cancer (ICC) represent a dire global health inequity, with 85 percent of incident cases and 90 percent of deaths occurring in low- and middle-income countries (LMICs).1 ICC is the leading cause of cancer death among women living with HIV (WLWH) in sub-Saharan Africa, which accounts for 71% of the global burden of HIV infection, despite being home to only 12% of the global population.2 Compared to HIV-negative women, WLWH have increased incidence and persistence of human papillomavirus (HPV),3 have a shorter time from HPV infection to development of p
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Ransom, Jacob L., Ka C. Wong, Jacqueline Kircher, Courtney Usry, and Christopher Larson. "Bidirectional Ventricular Tachycardia in a Young Female: A Case of Andersen-Tawil Syndrome." Military Medicine, February 19, 2021. http://dx.doi.org/10.1093/milmed/usab076.

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ABSTRACT Bidirectional ventricular tachycardia (VT) is a rare ventricular dysrhythmia with a limited differential diagnosis that includes digitalis toxicity, catecholaminergic polymorphic VT, aconite poisoning, and genetic channelopathy syndromes, specifically, Andersen–Tawil syndrome (ATS). We present a case of a young female with palpitations found to have bidirectional VT on cardiac event monitor and strong family history of cardiac dysrhythmias. Her physical examination findings included minor dysmorphic features of mandibular hypoplasia, hypertelorism, and clinodactyly. The patient was cl
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Yang, Jing, Kun Li, Tingting Lv, Ying Xie, Fang Liu, and Ping Zhang. "Case report: Mexiletine suppresses ventricular arrhythmias in Andersen-Tawil syndrome." Frontiers in Cardiovascular Medicine 9 (August 25, 2022). http://dx.doi.org/10.3389/fcvm.2022.992185.

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It is arduous to determine clinical solutions for Andersen-Tawil syndrome (ATS) in patients intolerant of β-blocker. Here, we present the case of a 7-year-old boy with periodic paralysis and dysmorphic features who experienced syncope four times during exercise. His ECG revealed enlarged U waves and QU-prolongation associated with ATS-specific U wave patterns, frequent PVCs, and non-sustained bidirectional or polymorphic ventricular tachycardia. The genetic test showed a de novo missense R218W mutation of KCNJ2. With the diagnosis of ATS and intolerance of β-blocker, the patient was prescribed
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"Globale Entwicklung der Healthy Life Expectancy (HALE) zwischen 1990 und 2017." Das Gesundheitswesen 81, no. 08/09 (2019): 579–80. http://dx.doi.org/10.1055/a-0955-0540.

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Weltweit ist aufgrund verbesserter Lebensbedingungen und einer hochwertigeren medizinischen Versorgung ein kontinuierlicher Anstieg der Lebenserwartung zu verzeichnen. Allerdings nimmt die gesunde Lebenserwartung („Healthy Life Expectancy“ [HALE]) nicht in gleichem Maß zu. Die „Global Burden of Diseases, Injuries, and Risk Factors Study“ (GBD) 2017 hat für 195 Länder über 28 Jahre hinweg unter anderem Muster und Trends zu der HALE analysiert.
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"Psychosozialer Stress durch Covid-19 – Pflegepersonal in Deutschland fühlte sich zu Beginn der Pandemie psychisch stark belastet." Gesundheitsökonomie & Qualitätsmanagement 25, no. 05 (2020): 227–28. http://dx.doi.org/10.1055/a-1288-8789.

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Kramer V et al. Subjective burden and perspectives of German healthcare workers during the COVID-19 pandemic. Eur Arch Psychiatry Clin Neurosci. 2020 Aug 19. doi: 10.1007/s00406–020–01183–2 [Epub ahead of print] Beschäftigte im Gesundheitswesen, die Covid-19-Patienten und -Patientinnen pflegen und behandeln, waren zu Beginn der Pandemie gestresster und fühlten sich deutlich stärker belastet, als andere Beschäftigte, insbesondere in der Pflege. Dies ist das Ergebnis der deutschlandweit ersten Studie dazu. Insgesamt zeigten die Beschäftigten im deutschen Gesundheitswesen hohe Zustimmungsraten zu
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Smith, Jamie L., Jill M. Killian, Nathan Shippee, et al. "Burden of Treatment in Patients With Heart Failure." Journal of the American Heart Association, May 15, 2025. https://doi.org/10.1161/jaha.124.039695.

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Background Heart failure self‐care can contribute to a high daily workload and treatment burden. The goal of this cohort study was to assess the characteristics and outcomes associated with burden of treatment (BoT). Methods Surveys comprising validated instruments to measure BoT and other constructs were mailed to patients with heart failure in Southeastern Minnesota. Participants were divided into tertiles by BoT scores. Associations of clinical variables with BoT were examined using multinomial logistic regression. Associations of BoT with mortality and hospitalizations were examined using
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Hartle, Cassandra, Ian Dinsmore, Tooraj Mirshahi, Jonathan Luo, Robert Mangano, and Bryn Moore. "Abstract 4147136: Functional Consequences and Phenotypic Manifestations of KCNJ2 Variants in Andersen-Tawil Syndrome." Circulation 150, Suppl_1 (2024). http://dx.doi.org/10.1161/circ.150.suppl_1.4147136.

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Introduction: Andersen-Tawil Syndrome (ATS) is a rare genetic disorder characterized by periodic paralysis, skeletal abnormalities, and elongated QTc. ATS is caused by mutations in KCNJ2 , which encodes the inwardly rectifying Kir2.1 channel that constitutes IK 1 in the heart. Out of 2.3 million subjects in our EHR, only 3 had an ATS diagnosis, confirmed by clinical genetic testing. Due to the low prevalence and variable expressivity, diagnosing ATS is challenging. Hypothesis: ATS is often misdiagnosed and protein truncating variants (PTV) in KCNJ2 are not sufficient to cause disease. Methods:
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Younis, Arwa, Mehmet Aktas, Ilan Goldenberg, et al. "Abstract 17496: The Effect of Statin on Ventricular Tachyarrhythmia Burden." Circulation 142, Suppl_3 (2020). http://dx.doi.org/10.1161/circ.142.suppl_3.17496.

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Introduction: Statins may reduce risk for ventricular tachyarrhythmia (VTA) in patients with implantable cardioverter defibrillator (ICD). Ranolazine was shown to increase plasma concentrations of statin. Objective: To evaluate the effect of statin on recurrent VTA, and to explore the interaction with both Ranolizine and cardiomyopathy (CMP) origin. Methods: The Andersen-Gill extension of the Cox proportional hazards regression was used to assess the association between statin treatment and the risk for recurrent VTA among 1012 ICD patients enrolled in the Ranolazine Implantable Cardioverter-D
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