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Littérature scientifique sur le sujet « Calvaria de rat »

Auteur : Grafiati

Publié le 8 juillet 2023

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Articles de revues sur le sujet "Calvaria de rat"

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Anavi, Yakir, Gal Avishai, Shlomo Calderon et Dror M. Allon. « Bone Remodeling in Onlay Beta-Tricalcium Phosphate and Coral Grafts to Rat Calvaria : Microcomputerized Tomography Analysis ». Journal of Oral Implantology 37, n^o 4 (1 août 2011) : 379–86. http://dx.doi.org/10.1563/aaid-joi-d-09-00128.1.

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Abstract This study was conducted to establish the efficiency of microcomputerized tomography (micro-CT) in detection of trabecular bone remodeling of onlay grafts in a rodent calvaria model, and to compare bone remodeling after onlay grafts with beta-tricalcium phosphate (TCP) or coral calcium carbonate. Ten rats received calvarial onlay blocks—5 with TCP and 5 with coral calcium carbonate. The grafts were fixed with a titanium miniplate screw and were covered with a collagen resorbable membrane. Three months after surgery, the calvaria were segmented, and a serial 3-dimensional micro-CT scan of the calvarium and grafted bone block at 16-micrometer resolution was performed. Image analysis software was used to calculate the percentage of newly formed bone from the total block size. Newly formed bone was present adjacent to the calvarium and screw in all specimens. The mean area of newly formed bone of the total block size ranged from 34.67%–38.34% in the TCP blocks, and from 32.41%–34.72% in the coral blocks. In the TCP blocks, bone remodeling was found to be slightly higher than in the coral blocks. Micro-CT appears to be a precise, reproducible, specimen-nondestructive method of analysis of bone formation in onlay block grafts to rat calvaria.

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Badwelan, Mohammed, Mohammed Alkindi, Osama Alghamdi, Abeer Ahmed, Sundar Ramalingam et Ali Alrahlah. « Bone Regeneration Using PEVAV/β-Tricalcium Phosphate Composite Scaffolds in Standardized Calvarial Defects : Micro-Computed Tomographic Experiment in Rats ». Materials 14, n^o 9 (3 mai 2021) : 2384. http://dx.doi.org/10.3390/ma14092384.

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Bone regeneration using beta-tricalcium phosphate (β-TCP) can be practiced using a biocomposite scaffold. Poly(ethylene-co-vinylalcohol)/poly(δ-valerolactone)/β-tricalcium phosphate (PEVAV/β-TCP) composite scaffolds showed promising in vitro results. This study evaluated the bone regenerative potential of PEVAV/β-TCP biocomposite scaffolds in standardized calvarial defects in a rat model over 4 and 10 weeks. Bilateral calvarial defects (5 mm in diameter and about 1.5 mm thick, equivalent to the thickness of the calvaria) were created in 40 male Wistar albino rats. The defects were grafted with either commercially available β-TCP (positive control), PEVAV/β-TCP 70, or PEVAV/β-TCP 50, or left empty (negative control), depending on the group to which the animal was randomly assigned, to be covered before flap closure with resorbable collagen membrane (RCM). At 4 and 10 weeks post-surgery, the collected rat calvaria were evaluated using micro computed tomography (micro-CT) analysis, to assess the newly formed bone volume (NFBV), newly formed bone mineral density (NFBMD), and remaining graft volume (RGV). The results showed that calvarial defects grafted with the PEVAV/β-TCP biocomposite exhibited higher NFBV than did control defects, both at 4 and 10 weeks post-surgery. Furthermore, calvarial defects grafted with PEVAV/β-TCP 70 showed the highest NFBV among all grafting conditions, with a statistically significant difference recorded at 10 weeks post-surgery. The PEVAV/β-TCP composite scaffold showed potentiality for the regeneration of critical-sized calvarial bone defects in a rat model.

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Allon, Irit, Yakir Anavi et Dror M. Allon. « Topical Simvastatin Improves the Pro-Angiogenic and Pro-Osteogenic Properties of Bioglass Putty in the Rat Calvaria Critical-Size Model ». Journal of Oral Implantology 40, n^o 3 (1 juin 2014) : 251–58. http://dx.doi.org/10.1563/aaid-joi-d-11-00222.

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Objective was to describe the effect of bioactive glass putty with and without topical simvastatin on new bone formation in critical-sized defects of rat calvaria. A calvarial bone defect was created in 20 male Wistar rats and filled with bioactive glass alone (n = 10) or combined with simvastatin (n = 10). After 4 weeks, the defects were histomorphometrically evaluated for volume fraction (Vv) of woven bone, vessel density, bioglass quantity, and inflammation. Compared to the bioglass-only group, rats treated with simvastatin had greater Vv of blood vessels (3.3% ± 0.7 vs 1.6% ± 0.1, P = .0002) and new bone (2.3% ± 0.2 vs 1.8% ± 2.5, P = .003). The Vv of the bioglass remnants in the bioglass-only group was higher than in the group treated with simvastatin (2.4% ± 0.08 vs 1.7% ± 0.3, P < .0004). Chronic inflammation was noted in 1 rat from each group. Topical simvastatin seems to improve the pro-angiogenic and pro-osteogenic properties of bioglass putty in rat calvaria critical-size defects without significant inflammation.

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Ishimoto, Takuya, Tatsushi Sakamoto et Takayoshi Nakano. « Orientation of Biological Apatite in Rat Calvaria Analyzed by Microbeam X-Ray Diffractometer ». Materials Science Forum 638-642 (janvier 2010) : 576–81. http://dx.doi.org/10.4028/www.scientific.net/msf.638-642.576.

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A microbeam X-ray diffractometer is a powerful tool to analyze oriented biological apatite (BAp) crystallites in bones since BAp orientation is one of the dominant controlling factors for bone mechanical function. The formation of BAp orientation seems to be partly affected by the bone formation process, including membranous or intracartilaginous ossification, the direction and the rate of bone growth, the mineral apposition rate, etc. However, the detailed process and the mechanisms of the organization of BAp orientation during the bone formation process are still not understood. In this study, we focused on a calvarial bone as a flat bone to establish a procedure to analyze BAp orientation in calvarial bone and examined the variation in BAp orientation with age and position in growing rats. Microbeam X-ray diffraction analysis was performed on the extracted calvaria of 5- to 10-week-old Wister rats. The transmission optical system was selected to analyze the orientation of the BAp c-axis along the bone surface. An incident molybdenum (Mo)-K X-ray, which was collimated into a 300-m diameter, was vertically radiated on the calvaria surface, and the diffraction pattern was registered on an imaging plate. Diffraction peak intensities from the (002) and (310) planes of the hexagonal BAp were detected, and then an intensity ratio of (002)/(310) was calculated to evaluate the degree of BAp orientation. BAp orientation in a calvarial bone was successfully analyzed, and the two-dimensional distribution of the BAp c-axis along the calvarial bone surface was identified. A parietal bone, which is a part of the calvarial bone, showed a unique two-dimensional distribution of the BAp c-axis. The distribution remarkably changed depending on the position on a parietal bone and age. The anisotropy in the preferred BAp orientation was very significant at a region that showed high growth rate. Even though the bone formation process seems to affect BAp orientation in the parietal bone, further investigation is needed to understand the mechanism for the development of BAp texture, which is closely related to bone mechanical function.

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Agarwal, M. K., F. Mirshahi, M. Mirshahi, S. Bracq, J. Chentoufi, M. Hott, A. Jullienne et P. J. Marie. « Evidence for receptor-mediated mineralocorticoid action in rat osteoblastic cells ». American Journal of Physiology-Cell Physiology 270, n^o 4 (1 avril 1996) : C1088—C1095. http://dx.doi.org/10.1152/ajpcell.1996.270.4.c1088.

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Aldosterone significantly enhanced the proliferation of osteoblastic cells from rat calvaria, and this effect was inhibited by RU 26752 and ZK 91587, two antagonists specific to the mineralocorticoid receptor (MCR). In addition, aldosterone inhibited the activity of alkaline phosphatase, a marker of the osteoblastic phenotype, and this effect was also reversed by RU 26752. Cytoplasmic staining of MCR was observed in rat calvaria osteoblasts incubated with a specific polyclonal antiserum raised against rat kidney MCR. This anti-MCR immunoglobulin G immunoprecipitated and macroaggregated the MCR-[3H]RU 26752 complex in osteoblastic cytosol. A single 98-kDa band was observed when osteoblastic cytosol was analyzed by Western blotting with anti-MCR serum. The 98-kDa band was also obtained after autoradiography of irradiated osteoblastic cytosol-[3H]R 5020 complex, and this was abolished in the presence of RU 26752. A p26MR probe, specific to COOH-terminal end of MCR, hybridized with the predicted product after amplification of total cell RNA by polymerase chain reaction technique. Furthermore, hybridization of poly(A)+ mRNA from at calvaria osteoblastic cells with the p26MR probe revealed a major band of approximately 4.2 kb. Collectively, our studies demonstrate the existence of a functional MCR in rat calvaria osteoblasts.

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Schmidt, Luis Eduardo, Henrique Hadad, Igor Rodrigues de Vasconcelos, Luara Teixeira Colombo, Rodrigo Capalbo da Silva, Ana Flavia Piquera Santos, Lara Cristina Cunha Cervantes et al. « Critical Defect Healing Assessment in Rat Calvaria Filled with Injectable Calcium Phosphate Cement ». Journal of Functional Biomaterials 10, n^o 2 (13 mai 2019) : 21. http://dx.doi.org/10.3390/jfb10020021.

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(1) Background: The tissue engineering field has been working to find biomaterials that mimic the biological properties of autogenous bone grafts. (2) Aim: To evaluate the osteoconduction potential of injectable calcium phosphate cement implanted in critical defects in rat calvaria. (3) Methods: In the calvarial bone of 36 rats, 7-mm diameter critical size defects were performed. Afterwards, the animals were randomly divided into three groups according to filler material: a blood clot group (BC), blood clot membrane group (BCM), and an injectable β-tricalcium phosphate group (HBS) cement group. After periods of 30 and 60 days, the animals were euthanized, the calvaria was isolated, and submitted to a decalcification process for later blades confection. Qualitative and quantitative analysis of the neoformed bone tissue were conducted, and histometric data were statistically analyzed. (4) Results: Sixty days post-surgery, the percentages of neoformed bone were 10.67 ± 5.57 in group BC, 16.71 ± 5.0 in group BCM, and 55.11 ± 13.20 in group HBS. The bone formation values in group HBS were significantly higher (p < 0.05) than in groups BC and BCM. (5) Conclusions: Based on these results, it can be concluded that injectable calcium phosphate cement is an osteoconductive material that can be used to fill bone cavities.

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Kim, Duck Hyun, Kang Sik Lee, Jung Hwa Kim, Jae Suk Chang et Yung Tae Kim. « The Influence of Bioactive Glass Particles on Osteolysis ». Key Engineering Materials 330-332 (février 2007) : 193–96. http://dx.doi.org/10.4028/www.scientific.net/kem.330-332.193.

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We observed the cytotoxicity of human bone marrow stromal cells(hBMSCs) by microparticles of bioactive glass with four particle groups(same chemical composition-45S5 but produced by two different manufacturer and two different size groups). In vivo test using rat calvaria were also carried out. The apoptosis rates of all small particle groups(10-20 ㎛) were increased than large(500-700 ㎛ or 200-900 ㎛) particle groups in any culture time and any amount of particles with statistical significance. In vivo study we observed pathologic signs such as macrophages and foreign-body giant cells in rat calvaria by micro-particles of bioglass. Small(10- 20 ㎛) sized particles induced foreign body reaction and bone resorption. There was proliferation of macrophages and cells in large number. But in large particle groups, only fibroblasts were surrounding the particles. The micro-particles of bioglass induced apoptosis of hBMSC and foreign body reaction in calvaria of rat, therefore micro-particles of bioglass may cause osteolysis if used in replacement arthroplasty.

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Nasirzade, Jila, Karol Alí Apaza Alccayhuaman, Zahra Kargarpour, Ulrike Kuchler, Franz Josef Strauss, Layla Panahipour, Carina Kampleitner, Patrick Heimel, Frank Schwarz et Reinhard Gruber. « Acid Dentin Lysate Failed to Modulate Bone Formation in Rat Calvaria Defects ». Biology 10, n^o 3 (5 mars 2021) : 196. http://dx.doi.org/10.3390/biology10030196.

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Autogenous tooth roots are increasingly applied as a grafting material in alveolar bone augmentation. Since tooth roots undergo creeping substitution similar to bone grafts, it can be hypothesized that osteoclasts release the growth factors stored in the dentin thereby influencing bone formation. To test this hypothesis, collagen membranes were either soaked in acid dentin lysates (ADL) from extracted porcine teeth or serum–free medium followed by lyophilization. Thereafter, these membranes covered standardized 5-mm-diameter critical-size defects in calvarial bone on rats. After four weeks of healing, micro-computed tomography and histological analyses using undecalcified thin ground sections were performed. Micro-computed tomography of the inner 4.5 mm calvaria defects revealed a median bone defect coverage of 91% (CI: 87–95) in the ADL group and 94% (CI: 65–100) in the control group, without significant differences between the groups (intergroup p > 0.05). Furthermore, bone volume (BV) was similar between ADL group (5.7 mm3, CI: 3.4–7.1) and control group (5.7 mm3, CI: 2.9–9.7). Histomorphometry of the defect area confirmed these findings with bone area values amounting to 2.1 mm2 (CI: 1.2–2.6) in the ADL group and 2.0 mm2 (CI: 1.1–3.0) in the control group. Together, these data suggest that acid dentin lysate lyophilized onto collagen membranes failed to modulate the robust bone formation when placed onto calvarial defects.

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Schmid, Christoph, Irene Schläpfer, Eva Futo, Margaretha Waldvogel, Jürg Schwander, Jürgen Zapf et E. Rudolf Froesch. « Triiodothyronine (T3) stimulates insulin-like growth factor (IGF)-1 and IGF binding protein (IGFBP)-2 production by rat osteoblasts in vitro ». Acta Endocrinologica 126, n^o 5 (mai 1992) : 467–73. http://dx.doi.org/10.1530/acta.0.1260467.

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Osteoblast-like cells prepared from neonatal rat calvariae and grown under serum-free conditions produce IGF-1 and IGFBPs. In contrast to growth hormone, T3 and PTH increased both IGF-1 mRNA expression and net IGF-1 release in calvaria cells. In addition, they stimulated net production of IGFBP-3 and of an IGFBP with an apparent molecular weight of 32 kDa which was recognized by an antiserum against rat IGFBP-2. Bone cells expressed remarkably high levels of mRNA for IGFBP-2, the predominant IGFBP in serum of newborn rats. T3 at low physiological concentrations but not growth hormone stimulated IGFBP-2 mRNA expression and IGFBP-2 production in bone cells in vitro. Thus, IGFBPs are differentially regulated by these hormones and may play an autocrine/paracrine regulatory role in bone.

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Silva, I. I. C., S. Pimentel-Soares, Rafael C. Bittencourt et José Mauro Granjeiro. « Natural Bovine Anorganic Apatite and Collagen Presents Osteoconductivity and Contribute to Bone Repair of Rat Calvaria Critical Size Defect ». Key Engineering Materials 396-398 (octobre 2008) : 249–52. http://dx.doi.org/10.4028/www.scientific.net/kem.396-398.249.

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The aim of this study was verify the biological efficacy of the use of a xenograft for bone loss therapy. Blood clot, particulate autogenous bone or anorganic bovine xenograft filled critical size defects (CSD) in rat calvaria (8mm diameter). After 0, 7, 30 and 90 days the animals were killed and macroscopic, radiographic and histopathological analysis were conducted. Although no treatment promoted the total closure of bone defect, autogenous bone group had better bone repair after 90 days, followed by xenograft group that exhibited direct bone neoformation onto, and around, the particles confirming its osteoconductivity. In conclusion, the xenograft tested in vivo showed biocompatibility, biodegradability and osteoconductive properties in rat calvaria CSD.

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Thèses sur le sujet "Calvaria de rat"

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Stronski, Stefan A. Bettschen-Camin Liana. « Bisphosphonates inhibit 1,25-Dihydroxyvitamin D₃ induced osteocalcin synthesis in the rat in vivo and in the rat calvaria in vitro / ». [S.l : s.n.], 1987. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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Burim, Rafael Augusto. « Avaliação da reparação de defeitos ósseos críticos na calvária de ratos Wistar sob ação sistêmica de Icariin : estudo radiográfico, histomorfológico e histomorfométrico ». Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/23/23149/tde-02092013-180120/.

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A reconstrução de defeitos ósseos críticos é alvo de inúmeras pesquisas em cirurgia bucomaxilofacial. Tais pesquisas visam, de maneira geral, a optimização da neoformação óssea e a eliminação dos procedimentos de remoção de osso autógeno para reconstrução. Os modelos animais têm sido a metodologia mais utilizada para avaliar a eficácia de novas substâncias e biomateriais na reparação óssea. O objetivo desta pesquisa foi avaliar a influência de um flavonóide, o icariin, na reparação óssea de defeitos críticos confeccionados na calvária de ratos Wistar. Um defeito ósseo crítico circular foi confeccionado em 40 calvarias de ratos por meio de uma broca trefina de 8 mm de diâmetro sob irrigação salina constante. Ao final dos procedimentos cirúrgicos, os animais foram divididos, aleatoriamente, em grupo teste (n=20), que recebeu o icariin, na dose de 125 mg/kg de peso e grupo controle (n=20), que recebeu soro fisiológico. Ambas as substâncias foram administradas por meio de gavagem até o dia da eutanásia. Ao final de cada período observacional de 7, 14, 21 e 42 dias, 5 animais de cada grupo foram eutanasiados e as amostras da calvária foram removidas e mantidas em formol 10% por 48 horas. As calvárias foram radiografadas e, após descalcificação, foram submetidas à avaliação histológica com coloração hematoxilina-eosina sob microscópio de luz. Os defeitos foram analisados considerando a diminuição da área do defeito na imagem radiográfica, as características de reparo ósseo e a osteogênese na região da ferida. Os resultados da análise radiográfica mostraram que a área do defeito ósseo no grupo teste foi significativamente menor que no grupo controle em todos os períodos observacionais. A avaliação histológica mostrou um aumento na neoformação óssea do grupo teste (p=0,02). A histomorfometria demonstrou osteogênese significante no grupo teste com 7 dias (p=0,021), 14 dias (p=0,014), 21 dias (p=0,021) e 42 dias (p=0,009). Foi possível concluir que o icariin sistêmico induziu uma maior neoformação óssea em defeitos críticos.
Bone critical defect reconstruction is an important target in current oral surgery research. Contemporary research has been searching for osteogenesis optimization to minimize the necessity of using autogenous bone grafts procedures. Animal models have been the widespread methodology to evaluate the effect of different new substances and biomaterials in bone healing. The aim of this study was to assess the influence of systemic daily flavonoid, icariin, in the repair of calvaria critical size defects induced in Wistar rats. A round critical size defect was performed centrally in 40 rats calvaria using an 8mm trephine under sterile saline solution irrigation. After surgery, half the animals, randomly, received by gavage daily doses of 125mg/Kg-icariin (Test Group) till the euthanasia. The other half (Control Group) received the same volume of saline solution. Five animals of each group were euthanized after 7, 14, 21 and 42 days postoperatively. The rats calvaria were removed, fixed in 10% formalin for 48 hours. Calvarias were X-rayed and after decalcification they underwent histological examination with hematoxylin eosin stain under a light microscope. Defects were analyzed considering area diminishing in X-ray image, bone healing characteristics and osteogenesis in the defect region. Results showed that bone defect area in Test Group was significant smaller in all observational periods. Histological evaluation showed an increased expression in bone trabeculae neoformation in Test Group (p=0,02). Histomorphometry demonstrated significant osteogenesis in Test Group at 7 days (p=0,021), 14 days (p=0,014), 21 days (p=0,021) and 42 days (p=0,009). It was concluded that systemic icariin induced a more expressive bone healing in critical size defects in rats.

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Molteni, Alexandra. « Interactions entre proteoglycannes sulfates et facteur de croissance fibroblastique-2 dans la chondro-osteogenese du condyle mandibulaire et l'osteogenese de la calotte cranienne de rat ». Paris 5, 1998. http://www.theses.fr/1998PA05M106.

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Anagnostou, Fani. « Caracterisation de l'activite phosphohydrolase de l'ecto-phosphatase alcaline et son role dans la mineralisation dans les cellules de calvaria de rat foetal en culture ». Paris 7, 1996. http://www.theses.fr/1996PA07GA02.

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NAAMAN, BOU-ABBOUD NADA. « Influence des biomateriaux alloplastiques, sur la reparation osseuse : etudes in vivo des potentiels osteoconducteurs et osteoinducteurs ». Paris 7, 1997. http://www.theses.fr/1997PA07GA02.

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D'Aoust, Paul R. « The use of bisphosphonates to promote healing of rat calvarial wounds ». Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0027/MQ40754.pdf.

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Mauro, Frank Armand. « Assessment of biodegradable calcium polyphosphate for bone substitute applications in the healing of the rat calvarium ». Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0004/MQ45973.pdf.

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Raman, Harini. « AN ORGANIC BOVINE HYDROXYAPATITE-PLGA COMPOSITES FOR BONE TISSUE ENGINEERING ». UKnowledge, 2005. http://uknowledge.uky.edu/gradschool_theses/201.

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The objective of the present study was to synthesize porous, biodegradable poly (D, l- lactide-co-glycolide) PLGA-B-HA (Bovine hydroxyapatite) composite and evaluate the effect of ceramic content on bone marrow cell differentiation in vitro. A macroporous biodegradable PLGA-B-HA composite with the pore size varying from 0.1 to 1000?? and a highly interconnected structure was fabricated using the freeze-drying/lyophilization technique. A pilot study was done to determine the effects of B-HA on to the osteoblast function. The main study was done to determine the effect of the increase in B-HA concentration on to the mesenchymal stem cell differentiation. Morphological characteristics of the composites were analyzed using FTIR and SEM/EDX analysis. The composites were seeded with neonatal rat calvarial osteoblasts (NRCO). The polymer: ceramic ratio in this study was 35%:65%. For comparison parallel experiments involving pure HA-200 discs were performed. SEM results indicated a higher proliferation and mineralization on PLGA-B-HA composites than pure HA discs. In addition, we evaluated the in vitro characteristics of PLGA-B-HA composites with varying ratios, i.e., 1:1, 1:2 and 1:3, seeded with rat marrow cells. FTIR indicated an increase in the area under the ceramic peak as ceramic concentration was increased. In addition, the average roughness values increased in the order of 1:3 andgt; 1:2 andgt; 1:1. Both compressive strength and modulus of 1:1 were significantly higher than 1:2 and 1:3 PLGA-B-HA composites. No significant difference in compressive modulli and strengths could be observed for 1:2 and 1:3 PLGA-B-HA composites. Cellular activity was determined by measuring AP activity, total protein analysis and osteocalcin concentration. Evaluation of alkaline phosphatase activity showed bone cells attached to 1:3 (PLGA-B-HA) expressed significantly higher alkaline phosphatase as compared to 1:1 and 1:2 PLGA-B-HA composites. In addition, cells seeded on to 1:3 composites secreted significantly higher osteocalcin and at a relatively short time period as compared to the other samples. Corrosion studies (ICP) and pH values indicate minimal difference in the concentration of Ca and P and pH in tissue culture media for all the samples at the end of all time periods. Hence we conclude that an increase in the ceramic concentration stimulated mesenchymal stem cell differentiation thereby promoting osteogenesis.

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Silva, Claudia Jordão. « Efeito de eletroestimulação sobre o processo de reparo de cavidade ossea cirurgica, com ou sem enxerto osseo. Estudo histologico em calvaria de coelho ». [s.n.], 1996. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289431.

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Orientador: Jose Ricardo de Albergaria-Barbosa
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba
Made available in DSpace on 2018-07-21T20:50:26Z (GMT). No. of bitstreams: 1 Silva_ClaudiaJordao_M.pdf: 4090867 bytes, checksum: bfd1ff3ed0e4830528fe82ad6f674596 (MD5) Previous issue date: 1996
Resumo: O propósito deste trabalho foi avaliar histologicamente o processo de reparo de defeitos ósseos, criados cirurgicamente em calvária de coelho, com ou sem enxerto ósseo e submetidos ou não a eletroestimulação. Foram utilizados 18 coelhos, sendo que cada um deles recebeu duas osteotomias na calvária. Na osteotomia do osso parietal direito o fragmento removido foi imediatamente reposicionado, sendo que no parietal esquerdo o fragmento foi desprezado. Os animais dos grupos tratados receberam a eletroestimulação por uma hora, durante 21 dias. Já os animais do grupo controle foram submetidos as mesmas condições de stress, porém com o aparelho desligado. Os períodos de sacrifício foram as quatro, oito e quinze semanas, compreendendo seis animais sacrificados em cada período. A análise dos espécimes sob a microscopia óptica revelou neoformação óssea em todos os animais. Nos animais com enxerto ósseo houve uma reparação mais acentuada quando comparados com o grupo sem enxerto. A eletroestimulação parece ter alterado o processo de reparo ósseo de maneira discreta
Abstract: The purpose of this research was to histologicalIy evaluate the healing process in bone defects surgically created in calvaria of rabbits, with or without bone grafts under the action of eletrotherapy or not. It were utilized 18 rabbits with 2 perfurations in each calvaria. In the right parietal bone perforation the fragment removed was immediately grafted in its place. lu the left parietal bone the fragment was thrown away. The animais in the treated group received 1 hour of eletrotherapy dayly, during 21 days. The animals in the control group were submitted to the same stress conditions, but the stimulator was turned off. The sacrifice periods were 4, 7 and 15 weeks, with 6 sacrificed animais in each group. The analysis of the specimens under optical microscopy revealed bone formation in all animals. In the animals with the bone grafted there was a more noticeable healing when compared to the animais in the control group. With regard the electrotherapy it seems to affect the bone healing mildly
Mestrado
Cirurgia e Traumatologia Buco-Maxilo-Faciais
Mestre em Clínica Odontológica

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Calvagna, Isabella [Verfasser], et Thomas [Akademischer Betreuer] Eckert. « Raising the quality of education in Europe by reducing the rate of early school leaving through international cooperation / Isabella Calvagna. Betreuer : Thomas Eckert ». München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2015. http://d-nb.info/1110749120/34.

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Livres sur le sujet "Calvaria de rat"

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Purpura, Kelly A. Phenotypic and functional analysis reveals a hierarchy of osteoprogenitors in fetal rat calvaria populations. Ottawa : National Library of Canada, 2002.

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Veillette, Christian J. H. Role of endothelin-1 in regulation of osteoblast differentiation and vascular endothelial growth factor-A in cell populations from fetal rat calvaria. Ottawa : National Library of Canada, 2002.

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Mauro, Frank Armand. Assessment of biodegradable calcium polyphosphate for bone substitute application in the healing of the rat calvarium. [Toronto : University of Toronto, Faculty of Dentistry], 1999.

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Ghent, Alan K. A comparison of two different concentrations of zyderm--a preparation of bovine skin collagen--on the healing of calvarial defects in the rat. [Toronto] : Faculty of Dentistry, University of Toronto, 1986.

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5

Li, Ivan Wing Sum. Regulation of bone matrix protein expression by recombinant human osteogenic protein-1 (RHOP-1 ; BMP-7) at different stages of osteogenic differentiation in fetal rat calvarial cells. Ottawa : National Library of Canada, 1995.

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Lee, Kui-Lai. Regulation of mineralization and of mRNA levels for several bone matrix proteins in rat calvaria cell cultures containing osteoid nodules. 1993.

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Chapitres de livres sur le sujet "Calvaria de rat"

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Bieli, M. « Histological Investigation of Bone Healing in the Rat Calvaria After the Use of Fibrin Glue ». Dans Fibrin Sealing in Surgical and Nonsurgical Fields, 110–18. Berlin, Heidelberg : Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-95720-8_12.

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Calasans-Maia, Monica, Gustavo Vicentis de Oliveira Fernandes, Alexandre M. Rossi, Eliane Pedra Dias, G. D. S. Almeida, F. F. Mitri et José Mauro Granjeiro. « Effect of Hydroxyapatite and Zinc-Containing Hydroxyapatite on Osseous Repair of Critical Size Defect in the Rat Calvaria ». Dans Bioceramics 20, 1273–76. Stafa : Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-457-x.1273.

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Yazici, Ilker, Sakir Unal et Maria Z. Siemionow. « Composite Hemiface/Calvarium Transplantation Model in Rat ». Dans Plastic and Reconstructive Surgery, 289–93. London : Springer London, 2014. http://dx.doi.org/10.1007/978-1-4471-6335-0_36.

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Kimura, Yasuko, Shigeshi Kikunaga, Ichiro Takahashi, Yuji Hatakeyama, Satoshi Fukumoto et Yasuyuki Sasano. « The physiological calcification process is replicated in a rat embryonic calvarial culture ». Dans Interface Oral Health Science 2009, 179–80. Tokyo : Springer Japan, 2010. http://dx.doi.org/10.1007/978-4-431-99644-6_40.

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Lee, Sang Bae, Kyeong Jun Park, Doug Youn Lee, Jeong Jong Park, Jae Sun Hwang, Yong Keun Lee, Kyoung Nam Kim et Kwang Mahn Kim. « A Histological Evaluation of Novel Cyanoacrylate-Based β-TCP Composite in Rat Calvarial Defects ». Dans Bioceramics 18, 1133–36. Stafa : Trans Tech Publications Ltd., 2006. http://dx.doi.org/10.4028/0-87849-992-x.1133.

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Song, Kun Young, Yoo Jung Um, Ui Won Jung, Yong Keun Lee, Seong Ho Choi et Chong Kwan Kim. « The Effects of Collagen Membrane Coated with PLGA on Bone Regeneration in Rat Calvarial Defects ». Dans Advanced Biomaterials VII, 357–60. Stafa : Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-436-7.357.

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Rahaman, Mohamed N., Yinan Lin, Wei Xiao, X. Liu et B. Sonny Bal. « Evaluation of Long-Term Bone Regeneration in Rat Calvarial Defects Implanted With Strong Porous Bioactive Glass (13-93) Scaffolds ». Dans Ceramic Transactions Series, 85–96. Hoboken, NJ, USA : John Wiley & Sons, Inc., 2015. http://dx.doi.org/10.1002/9781119190134.ch9.

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Shin, J. A., S. U. Im, S. E. Song, C. S. Kim, Se Young Choi, Yong Keun Lee, Kyoung Nam Kim, Chong Kwan Kim et Seong Ho Choi. « The Effects of Calcium Aluminate Cement According to Particle Sizes on Calvarial Bone Defects in Rats ». Dans Bioceramics 17, 113–16. Stafa : Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-961-x.113.

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Chae, Gyung Joon, Sang Bae Lee, Ui Won Jung, Yong Keun Lee, Chong Kwan Kim et Seong Ho Choi. « The Effects of Antibiotics Blended Chitosan Membranes on the Calvarial Critical Size Defect in Sprague Dawley Rats ». Dans Advanced Biomaterials VII, 857–60. Stafa : Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-436-7.857.

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Jung, Ui Won, J. A. Shin, K. J. Chae, Yong Keun Lee, Chong Kwan Kim et Seong Ho Choi. « The Effect of Lif-Maleic Acid Added Calcium Aluminate Bone Cement and Ca-PMMA Composite Bone Cement on Bone Regeneration in Rat Calvarial Defects ». Dans Key Engineering Materials, 851–54. Stafa : Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-422-7.851.

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Actes de conférences sur le sujet "Calvaria de rat"

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« In Situ Mechanical Behavior of Regenerating Rat Calvaria Bones Under Tensile Load via Synchrotron Diffraction Characterization ». Dans Residual Stresses 2018. Materials Research Forum LLC, 2018. http://dx.doi.org/10.21741/9781945291890-19.

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Legoux, J. G., F. Chellat, R. S. Lima, B. R. Marple, M. N. Bureau, H. Shen et G. A. Candeliere. « Development of Osteoblast Colonies on New Bioactive Coatings ». Dans ITSC2006, sous la direction de B. R. Marple, M. M. Hyland, Y. C. Lau, R. S. Lima et J. Voyer. ASM International, 2006. http://dx.doi.org/10.31399/asm.cp.itsc2006p0059.

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Abstract The aging baby boomer population coupled with an increase in life expectancy is leading to a rising number of active elderly persons in occidental countries. As a result, the orthopedic implant industry is facing numerous challenges such as the need to extend implant life, reduce the incidence of revision surgery and improve implant performance. This paper reports results of an investigation on the bioperformance of newly developed coating-substrate systems. Hydroxyapatite (HA) and nano-titania (nano-TiO2) coatings were produced on Ti-6Al-4V and fiber reinforced polymer composite substrates. In vitro studies were conducted in order to determine the capacity of bioactive coatings developed to sustain osteoblast cells (fetal rat calvaria) adherence, growth and differentiation. As revealed by SEM observations and alkaline phosphatase activity (ALP), cell adhesion and proliferation demonstrated that HA coatings over a polymer composite are at least as good as HA coatings made over Ti-6Al-4V substrate in terms of osteoblast cell activity. Nano-TiO2 coatings produced by high-velocity oxy fuel (HVOF) spraying led to different results. For short term cell culture (4.5 and 24 hrs), the osteoblasts appeared more flattened when grown on nano-TiO2 than on HA. The surface cell coverage after 7 days of incubation was also more complete on nano-TiO2 than HA. Preliminary results indicate that osteoblast activity after 15 days of incubation on nano-TiO2 is equivalent to or greater than that observed on HA.

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Ahmed, Rafay, Alan Wing Lun Law, Tsz Wing Cheung et Condon Lau. « Bone compositional study during healing of subcritical calvarial defects in rats by Raman spectroscopy ». Dans European Conferences on Biomedical Optics, sous la direction de Lothar D. Lilge et Ronald Sroka. SPIE, 2017. http://dx.doi.org/10.1117/12.2283272.

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NAKAGAWA, ATSUHIRO, TAKAYUKI HIRANO, TEIJI TOMINAGA, MASAYUKI EZURA, AKIRA TAKAHASHI et KAZUYOSHI TAKAYAMA. « APPLICATION OF SHOCK WAVE FOR THE TREATMENT OF BONE DEFECT IN THE SKULL : EXPERIMENT ON YOUNG RAT CALVARIUM ». Dans Proceedings of the Final Symposium of the Tohoku University 21st Century Center of Excellence Program. IMPERIAL COLLEGE PRESS, 2006. http://dx.doi.org/10.1142/9781860948800_0108.

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Güzel Meydanlı, Emine Elif. « Histological Evaluation of Combined Effect of Parathyroid Hormone and Strontium Ranelate on Calvarial Bone Healing in Ovariectomized Rats ». Dans 15th International Congress of Histochemistry and Cytochemistry. Istanbul : LookUs Scientific, 2017. http://dx.doi.org/10.5505/2017ichc.pp-02.

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Rapports d'organisations sur le sujet "Calvaria de rat"

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Gold, Chris, et David Sahar. Role of Endothelial Differentiated Adipose-derived Stem Cells in Repairing Calvarial Critical Size Defects in the Laboratory Rat (Rattus norvegicus). Fort Belvoir, VA : Defense Technical Information Center, juillet 2014. http://dx.doi.org/10.21236/ada608955.

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