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Articles de revues sur le sujet « Cancer bush »

Auteur : Grafiati

Publié le 4 juin 2021

Mis à jour le 2 février 2022

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1

Gospodarowicz, M. K., A. W. Fyles, and B. J. Cummings. "Ray Bush: The compleat oncologist." International Journal of Radiation Oncology*Biology*Physics 22, no. 5 (1992): 833–34. http://dx.doi.org/10.1016/0360-3016(92)90776-e.

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Gospodarowicz, M., and R. P. Hill. "Dr. Raymond S. Bush (1931–1990)." International Journal of Radiation Oncology*Biology*Physics 20, no. 2 (1991): 383–84. http://dx.doi.org/10.1016/0360-3016(91)90125-n.

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Lin, Hui, Glenn A. Jackson, Yuan Lu, et al. "Inhibition of Gli/hedgehog signaling in prostate cancer cells by “cancer bush”Sutherlandia frutescensextract." Cell Biology International 40, no. 2 (2015): 131–42. http://dx.doi.org/10.1002/cbin.10544.

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Acharya, Debabrata, Gill Enslin, Weiyang Chen, Maxleene Sandasi, Thandazile Mavimbela, and Alvaro Viljoen. "A chemometric approach to the quality control of Sutherlandia (cancer bush)." Biochemical Systematics and Ecology 56 (October 2014): 221–30. http://dx.doi.org/10.1016/j.bse.2014.06.009.

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Mathivha, Lutendo Patricia, Vuyisile Samuel Thibane, and Fhatuwani Nixwell Mudau. "Anti-diabetic and anti-proliferative activities of herbal teas, Athrixia phylicoides DC and Monsonia burkeana Planch. ex Harv, indigenous to South Africa." British Food Journal 121, no. 4 (2019): 964–74. http://dx.doi.org/10.1108/bfj-10-2018-0697.

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Purpose The purpose of this paper is to investigate the health and medicinal importance of bush tea (Athrixia phylicoides DC) and special tea (Monsonia burkeana Planch. ex Harv), two of Southern African indigenous herbal teas. Design/methodology/approach The two herbal teas, A. phylicoides and M. burkeana were extracted individually and in combined ratios for analysis. The phenolic content was determined and the different phenolic compounds were identified using thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC). The anti-diabetic activity of the teas was determi

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Kagan, A. Robert. "Dose, Response, and Survival in Metastatic Mammary Cancer." Journal of Clinical Oncology 3, no. 6 (1985): 890. http://dx.doi.org/10.1200/jco.1985.3.6.890.

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To the Editor: Congratulations to Hryniuk and Bush in their effort to make sense out of many different chemotherapy regimens. However, in my opinion, I think they interpret their results too narrowly. For example, in Fig 2 and especially Fig 4, a straight line parallel to the ordinate at 0.6 fits the data as well as a line with a slope. In Fig 5, I am led by the discussion to accept a line from a median survival time (MST) of 10 months to an MST of 20 months, as the CR plus PR percent is increased from 20% to 80%. A line parallel to the abscissa at an MST of 15 months fits the data as well. If

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Raselabe, M. B., M. Marais, A. R. Ndhlala, et al. "Root-knot nematodes in Cancer Bush: A serendipitous outcome of a dying plant." South African Journal of Botany 103 (March 2016): 346. http://dx.doi.org/10.1016/j.sajb.2016.02.161.

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Shaik, S., Y. H. Dewir, N. Singh, and A. Nicholas. "Influences of pre-sowing seed treatments on germination of the cancer bush (Sutherlandia frutescens), a reputed medicinal plant in arid environments." Seed Science and Technology 36, no. 3 (2008): 795–801. http://dx.doi.org/10.15258/sst.2008.36.3.31.

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Machate, David Johane, Elaine S. de Pádua Melo, Daniela G. Arakaki, et al. "High Concentration of Heavy Metal and Metalloid Levels in Edible Campomanesia adamantium Pulp from Anthropic Areas." International Journal of Environmental Research and Public Health 18, no. 11 (2021): 5503. http://dx.doi.org/10.3390/ijerph18115503.

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This study aimed to quantify the extent of heavy metal, non-metal and metalloid levels in the Campomanesia adamantium pulp obtained from an area crossed by road experiencing high large vehicle traffic and intensive agriculture modern farming, to monitor the health risks associated with pulp consumption by humans. For this purpose, in three spots located within this area, ripe fruits were collected on the roadside, bush and farm-margin. Pulp samples were digested by microwave-assisted equipment, and chemical elements were quantified by ICP OES. The concentrations of K, Pb, Se, Fe, Mo, Zn, Co, N

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Tollis, Marc, Elliott Ferris, Michael S. Campbell, et al. "Elephant Genomes Reveal Accelerated Evolution in Mechanisms Underlying Disease Defenses." Molecular Biology and Evolution 38, no. 9 (2021): 3606–20. http://dx.doi.org/10.1093/molbev/msab127.

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Abstract Disease susceptibility and resistance are important factors for the conservation of endangered species, including elephants. We analyzed pathology data from 26 zoos and report that Asian elephants have increased neoplasia and malignancy prevalence compared with African bush elephants. This is consistent with observed higher susceptibility to tuberculosis and elephant endotheliotropic herpesvirus (EEHV) in Asian elephants. To investigate genetic mechanisms underlying disease resistance, including differential responses between species, among other elephant traits, we sequenced multiple

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Mncwangi, N. P., and A. M. Viljoen. "Quantitative variation of amino acids in Sutherlandia frutescens (Cancer bush)—towards setting parameters for quality control." South African Journal of Botany 82 (September 2012): 46–52. http://dx.doi.org/10.1016/j.sajb.2012.06.009.

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Tonkin, Katia, and Ian Tannock. "Dose Intensity in Chemotherapy." Journal of Clinical Oncology 3, no. 6 (1985): 891. http://dx.doi.org/10.1200/jco.1985.3.6.891.

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To the Editor: In a recent article, Hryniuk and Bush have established a strong correlation between dose intensity of CMF (cyclophosphamide, methotrexate, 5-fluorouracil) chemotherapy, and the rate of tumor response in patients with metastatic breast cancer. They also observed a significant correlation between rate of tumor response and median survival time (r = .66, P < .001). The authors were careful to avoid the conclusion that there was a direct correlation between dose intensity and median survival, but it is surprising that they did not examine this more important relationship directly

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Chen, Yun, Ling Zeng, Wen Xiong, et al. "Anti-duck virus hepatitis mechanisms of Bush Sophora Root polysaccharide and its sulfate verified by intervention experiments." Virus Research 204 (June 2015): 58–67. http://dx.doi.org/10.1016/j.virusres.2015.04.013.

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Singh, N., S. Shaik, Y. Dewir, et al. "Detection of L-canavanine in the Cancer bush (Lessertia frutescens L.), a reputed anti-HIV/AIDS medicinal plant." South African Journal of Botany 75, no. 2 (2009): 440. http://dx.doi.org/10.1016/j.sajb.2009.02.165.

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van Schaik, K. D., and S. C. Thompson. "Indigenous beliefs about biomedical and bush medicine treatment efficacy for indigenous cancer patients: a review of the literature." Internal Medicine Journal 42, no. 2 (2012): 184–91. http://dx.doi.org/10.1111/j.1445-5994.2011.02598.x.

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Emery, J. D., F. M. Walter, V. Gray, et al. "Diagnosing cancer in the bush: a mixed-methods study of symptom appraisal and help-seeking behaviour in people with cancer from rural Western Australia." Family Practice 30, no. 3 (2013): 294–301. http://dx.doi.org/10.1093/fampra/cms087.

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van der Walt, Nicola B., Zahra Zakeri, and Marianne J. Cronjé. "The Induction of Apoptosis in A375 Malignant Melanoma Cells bySutherlandia frutescens." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–14. http://dx.doi.org/10.1155/2016/4921067.

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Sutherlandia frutescensis a medicinal plant indigenous to Southern Africa and is commonly known as the “cancer bush.” This plant has traditionally been used for the treatment of various ailments, although it is best known for its claims of activity against “internal” cancers. Here we report on its effect on melanoma cells. The aim of this study was to investigate whether an extract ofS. frutescenscould induce apoptosis in the A375 melanoma cell line and to outline the basic mechanism of action.S. frutescensextract induced apoptosis in A375 cells as evidenced by morphological features of apopto

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Zakynthinos, George, Theodoros Varzakas, and Dimitrios Petsios. "Sea Buckthorn (Hippophae Rhamnoides) Lipids and their Functionality on Health Aspects." Current Research in Nutrition and Food Science Journal 4, no. 3 (2016): 182–94. http://dx.doi.org/10.12944/crnfsj.4.3.04.

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Hippophae rhamnoides, also named as Sea Buckthorn(SB) is a spiny bush with long and narrow leaves, and orange yellow berries. It is native to Europe and mainly to Asia. The leaves, fruits and the seeds of sea bucHippophae rhamnoides, also named as Sea Buckthorn(SB) is a spiny bush with long and narrow leaves, and orange yellow berries. It is native to Europe and mainly to Asia. The leaves, fruits and the seeds of sea buckthorn contain many bioactive compounds. These compounds are various natural antioxidants such as ascorbic acid, tocopherols, carotenoids, flavonoids, whereas besides them all

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Makgato, Manaka J., Hintsa T. Araya, Christian P. du Plooy, Salmina N. Mokgehle, and Fhatuwani N. Mudau. "Effects of Rhizobium Inoculation on N2 Fixation, Phytochemical Profiles and Rhizosphere Soil Microbes of Cancer Bush Lessertia frutescens (L.)." Agronomy 10, no. 11 (2020): 1675. http://dx.doi.org/10.3390/agronomy10111675.

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Plant-beneficial microorganisms are determinants of plant health and productivity. However, the effects associated with secondary plant metabolism and interactions in the rhizosphere for Cancer bush Lessertia frutescens (L.) is unclear. The study was conducted to understand the mechanism of rhizobium inoculation for L. frutescens, variations in phytochemicals, soluble sugars, and soil–plant interactions in the rhizosphere. Four rhizobium inoculation levels (0, 100, 200, and 400 g) were evaluated under the field conditions to establish the antioxidant properties, soluble sugars, and rhizosphere

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Emery, J. D., F. M. Walter, V. Gray, et al. "Diagnosing cancer in the bush: a mixed methods study of GP and specialist diagnostic intervals in rural Western Australia." Family Practice 30, no. 5 (2013): 541–50. http://dx.doi.org/10.1093/fampra/cmt016.

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Gelderblom, W. C. A., E. Joubert, K. Gamieldien, L. Sissing, C. J. Malherbe, and G. Maritz. "Rooibos (Aspalathus linearis), honeybush (Cyclopia intermedia) and cancer bush (Sutherlandia frutescens subsp. microphylla) protect against tobacco-specific mutagenesis in vitro." South African Journal of Botany 110 (May 2017): 194–200. http://dx.doi.org/10.1016/j.sajb.2016.06.004.

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Dewir, Yaser Hassan, Nisha Singh, Shakira Shaik, and Ashley Nicholas. "Indirect regeneration of the Cancer bush (Sutherlandia frutescens L.) and detection of l-canavanine in in vitro plantlets using NMR." In Vitro Cellular & Developmental Biology - Plant 46, no. 1 (2009): 41–46. http://dx.doi.org/10.1007/s11627-009-9260-4.

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Intzes, Stergios, Marianthi Symeonidou, Konstantinos Zagoridis, Aikaterini Pentidou, and Spanoudakis Emmanouil. "SOCIOECONOMIC STATUS IS GLOBALLY A PROGNOSTIC FACTOR FOR OVERALL SURVIVAL OF MULTIPLE MYELOMA PATIENTS; SYNTHESIS OF STUDIES AND REVIEW OF THE LITERATURE." Mediterranean Journal of Hematology and Infectious Diseases 13, no. 1 (2020): e2021006. http://dx.doi.org/10.4084/mjhid.2021.006.

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Socioeconomic status (SES) is reflecting differences in sociodemographic factors affecting cancer survivorship. Deprived, low SES populations has a higher prevalence of multiple myeloma and worst survival, a gap that widens over time. Methods: We performed a meta-analysis of 16 studies (registries and cohorts) reporting survival data of myeloma patients according to SES. Ten studies reported Hazzard Ratio (HR) (95 % CI) and 16 studies reported p values. We combined the HR from 10 studies and by using the Mosteller-Bush formula we performed the synthesis of p values according to the area of the

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Olver, Ian N., Kate M. Gunn, Vikki E. Knott, Alwin Chong, Kristiaan Spronk, and Joan Cunningham. "Communicating cancer and its treatment to Australian Aboriginal patients with cancer: A qualitative study." Journal of Clinical Oncology 38, no. 15_suppl (2020): e24188-e24188. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e24188.

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e24188 Background: To enable clinicians to effectively communicate about cancer and its treatment to Aboriginal and Torres Strait (Aboriginal) people with cancer who need to make informed choices about the Western medicine offered, we sought strategies from health professionals with experience in that field. Methods: Semi-structured interviews were conducted face-to face or via telephone with the experienced health professionals and audio-recorded. Thematic analysis using a bottom up, essentialist/realist approach was employed to analyse the data, when data saturation was reached. Results: The

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Gall, Alana, Stuart Leske, Jon Adams, et al. "Traditional and Complementary Medicine Use Among Indigenous Cancer Patients in Australia, Canada, New Zealand, and the United States: A Systematic Review." Integrative Cancer Therapies 17, no. 3 (2018): 568–81. http://dx.doi.org/10.1177/1534735418775821.

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Background: Cancer ‘patients’ are increasingly using traditional indigenous and complementary medicines (T&CM) alongside conventional medical treatments to both cure and cope with their cancer diagnoses. To date T&CM use among Indigenous cancer patients from Australia, Canada, New Zealand, and the United States has not been systematically reviewed. Methods: We systematically searched bibliographic databases to identify original research published between January 2000 and October 2017 regarding T&CM use by Indigenous cancer patients in Australia, Canada, New Zealand, and the United

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Shahid, Shaouli, Ryan Bleam, Dawn Bessarab, and Sandra C. Thompson. ""If you don't believe it, it won't help you": use of bush medicine in treating cancer among Aboriginal people in Western Australia." Journal of Ethnobiology and Ethnomedicine 6, no. 1 (2010): 18. http://dx.doi.org/10.1186/1746-4269-6-18.

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Dhillon, Preet K., Shivani Patel, Theresa Gillespie, et al. "Integrating Breast Cancer Evaluation With a Cervical Cancer Toolkit for Low-Resource Settings." Journal of Global Oncology 4, Supplement 3 (2018): 13s. http://dx.doi.org/10.1200/jgo.18.10140.

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Purpose To address high breast cancer (BC) mortality globally and especially in low- and middle-income countries (LMICs), resource-stratified screening and treatment guidelines have been provided by global expert groups. How these guidelines are implemented and aligned with facility readiness in low-resource settings is less well understood. We propose to modify, apply, and evaluate a cervical cancer toolkit designed to evaluate facility readiness in LMICs as an implementation science tool for the treatment of BC. Methods We will draw upon an existing toolkit for cervical cancer, the Improving

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Shaik, Shakira, Nisha Singh, and Ashley Nicholas. "HPLC and GC analyses of in vitro-grown leaves of the cancer bush Lessertia (Sutherlandia) frutescens L. reveal higher yields of bioactive compounds." Plant Cell, Tissue and Organ Culture (PCTOC) 105, no. 3 (2010): 431–38. http://dx.doi.org/10.1007/s11240-010-9884-4.

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Zonyane, Samkele, Olaniyi A. Fawole, Chris la Grange, Maria A. Stander, Umezuruike L. Opara, and Nokwanda P. Makunga. "The Implication of Chemotypic Variation on the Anti-Oxidant and Anti-Cancer Activities of Sutherlandia frutescens (L.) R.Br. (Fabaceae) from Different Geographic Locations." Antioxidants 9, no. 2 (2020): 152. http://dx.doi.org/10.3390/antiox9020152.

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Extracts of Sutherlandia frutescens (cancer bush) exhibit considerable qualitative and quantitative chemical variability depending on their natural wild origins. The purpose of this study was thus to determine bioactivity of extracts from different regions using in vitro antioxidant and anti-cancer assays. Extracts of the species are complex and are predominantly composed of a species-specific set of triterpene saponins (cycloartanol glycosides), the sutherlandiosides, and flavonoids (quercetin and kaempferol glycosides), the sutherlandins. For the Folin-Ciocalteu phenolics test values of 93.3

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Symonds, Erin L., Izabela Konczak, and Michael Fenech. "The Australian fruit Illawarra plum (Podocarpus elatusEndl., Podocarpaceae) inhibits telomerase, increases histone deacetylase activity and decreases proliferation of colon cancer cells." British Journal of Nutrition 109, no. 12 (2012): 2117–25. http://dx.doi.org/10.1017/s0007114512004333.

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Fruit antioxidants have many health benefits including prevention of cancer development. The native Australian bush fruit Illawarra plum (Podocarpus elatusEndl., Podocarpaceae) has a high content of anthocyanin-rich phenolics, with an antioxidant capacity at levels higher than most fruits. In the present study the molecular mechanisms of the anti-proliferative activity of Illawarra plum on colorectal cancer cells were investigated. Non-tumorigenic young adult mouse colonic (YAMC) cells and tumorigenic human colonic (HT-29) cells were treated with a polyphenolic-rich Illawarra plum extract (0–1

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Mala John, Geraldine Sandana, Satoru Takeuchi, Ganesh Venkatraman, and Suresh Kumar Rayala. "Nordihydroguaiaretic Acid in Therapeutics: Beneficial to Toxicity Profiles and the Search for its Analogs." Current Cancer Drug Targets 20, no. 2 (2020): 86–103. http://dx.doi.org/10.2174/1568009619666191022141547.

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Nordihydroguaiaretic acid (NDGA) is a plant lignan obtained from creosote bush, Larrea tridentata and is known to possess antioxidant, anticancer activities and is used in traditional medicine in North America and Mexico. However, its prolonged consumption leads to liver damage and kidney dysfunction. Despite its toxicity and side effects, there is little awareness to forbid its consumption and its use in the treatment of medical ailments has continued over the years. Several reports discuss its therapeutic efficiency and its medical applications have tremendously been on the rise to date. The

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Dullah, Intan Christin, Sulandjari Sulandjari, and Supriyono Supriyono. "Abiotic Stress And Biofertilizer on The Pereskia bleo (Kunth) DC. Against Growth, Proline, and Antioxidants." SAINS TANAH - Journal of Soil Science and Agroclimatology 16, no. 1 (2019): 36. http://dx.doi.org/10.20961/stjssa.v16i1.25158.

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<p><em>Pereskia bleo</em> is a spiny bush from the genus Pereskia and family Cactaceae. Its leaves are shiny green, flowering, and fruitful. Some researchers to indicate that <em>P.bleo</em> leaves contain high antioxidants, anti-cancer, and are traditionally used for diabetic, hemorrhoids, hypertension, and gastric pain. The aim of this study was to determine the effect of salinity stress and water volume as well as the role of biofertilizer on the growth of <em>Pereskia bleo</em> and antioxidant content. Using Nested design (completely randomized fac

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Solipuram, Rajasree, Sowmya Koppula, Angela Hurst, et al. "Molecular and Biochemical Effects of a Kola Nut Extract on Androgen Receptor-Mediated Pathways." Journal of Toxicology 2009 (2009): 1–16. http://dx.doi.org/10.1155/2009/530279.

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The low incidence of prostate cancer in Asians has been attributed to chemopreventative properties of certain chemicals found in their diet. This study characterized the androgenic and chemopreventative properties of the Jamaican bush tea “Bizzy,” using androgen receptor positive and negative cell lines. Exposure of prostate cells to Biz-2 resulted in a growth inhibition (GI50) of 15 ppm in LNCaP cells and 3.6 ppm in DU145 cells. Biz-2 elicited a 2-fold increase in the mRNA of the anti-apoptotic gene Bcl2, with a 10-fold increase in that of the proapoptotic gene Bax. We observed a 2.4- to 7.5-

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Cuny, Eckehard. "Synthesis of Analogues of (+)-Gomphoside, a Potent HIF-1 Inhibitor and Cardenolide." Natural Product Communications 13, no. 3 (2018): 1934578X1801300. http://dx.doi.org/10.1177/1934578x1801300315.

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The milkweed bush Gomphocarpus fruticosus R.Br. found in Australia contains the steroidal glycoside (+)-gomphoside, its derivatives (-)-3'-dehydrogomphoside and (+)-3'- epi-gomphoside, as well as other glycoside compounds. The key structural features of these unique herbal agents are bislinked steroid to sugar linkages. (+)-Gomphoside is an extremely potent cardenolide and highly effective Hypoxia-Inducible Factor (HIF)-1 inhibitor. In addition, (+)-gomphoside exhibits strong cytotoxicity on human breast cancer cell lines. The syntheses of (+)-gomphoside analogues with modified steroidal D rin

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Rahman, Shakilur, Rizwan Ahmed Ansari, Hasibur Rehman, Suhel Parvez, and Sheikh Raisuddin. "Nordihydroguaiaretic Acid from Creosote Bush (Larrea tridentata) Mitigates 12-O-Tetradecanoylphorbol-13-Acetate-Induced Inflammatory and Oxidative Stress Responses of Tumor Promotion Cascade in Mouse Skin." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–10. http://dx.doi.org/10.1093/ecam/nep076.

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Nordihydroguaiaretic acid (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub,Larrea tridentata(Sesse and Moc. ex DC) Coville (creosote bush). It has a long history of traditional medicinal use by the Native Americans and Mexicans. The modulatory effects of topically applied NDGA was studied on acute inflammatory and oxidative stress responses in mouse skin induced by stage I tumor promoting agent, 12-O-tetradecanoylphorbol-13-acetate (TPA). Double TPA treatment adversely altered many of the marker responses of stage I skin tumor promotion cascade. Pret

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Dienaitė, Lijana, Milda Pukalskienė, Carolina V. Pereira, Ana A. Matias, and Petras Rimantas Venskutonis. "Valorization of European Cranberry Bush (Viburnum opulus L.) Berry Pomace Extracts Isolated with Pressurized Ethanol and Water by Assessing Their Phytochemical Composition, Antioxidant, and Antiproliferative Activities." Foods 9, no. 10 (2020): 1413. http://dx.doi.org/10.3390/foods9101413.

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Defatted by supercritical CO2, Viburnum opulus berry pomace (VOP) was subjected to consecutive extraction with pressurized ethanol (E) and water (W) and yielded 23% of VOP-E and 8% of VOP-W, respectively. The major phytochemical groups covering 42 identified and quantified constituents in VOP extracts were organic and phenolic acids, iridoids, quercetin and (epi)catechin derivatives, flavalignans, procyanidins, and anthocyanins. The on-line HPLC-DPPH•-scavenging assay revealed the presence of numerous antioxidants. VOP-E had a higher total phenolic content, was a stronger antioxidant (equivale

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Shailja Choudhary, Hemlata Kaurav, and Gitika Chaudhary. "Citraka (Plumbago zeylanica): A Potential Rejuvenator." International Journal for Research in Applied Sciences and Biotechnology 8, no. 2 (2021): 202–12. http://dx.doi.org/10.31033/ijrasb.8.2.26.

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Plumbago zeylanica is also known as chitraka, doctor bush, or leadwort. It is the most popular herbal plant that belongs to the family Plumbaginaceae or leadwort. Plumbagin is the most important chemical constituent present in the roots, leaves and stem of the plant that is responsible for various pharmacological actions including anti-malarial, anti-obese, anti-diabetic, anti-microbial, anti-ulcer, anti-inflammatory, anti-oxidant and anti-cancer. Traditionally it is used to treat variety of diseases such as dysmenorrhea, leprosy, anemia, rheumatic pain, cold, cough, arthritis and many more. I

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Wood, Lauren Virginia, Siva K. Gandhapudi, Karuna Sundarapandiyan, Frank K. Bedu-Addo, Gregory Conn, and Jerold G. Woodward. "R-DOTAP (Versamune): A novel enantiospecific cationic lipid nanoparticle that induces CD4 and CD8 cellular immune responses to whole protein and tumor-specific peptide antigens." Journal of Clinical Oncology 38, no. 15_suppl (2020): e15211-e15211. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e15211.

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e15211 Background: Immunotherapy approaches are limited in their ability to induce antigen-specific CD8+ T cells in vivo able to recognize and kill tumor cells. We developed a novel immunotherapy approach using enantiomerically pure, R-DOTAP cationic lipid nanoparticles and tumor-derived T cell antigens, and previously demonstrated that R-DOTAP formulations efficiently prime cytotoxic T cells through enhanced cross presentation and induction of type I interferons.[1] A phase I clinical trial of a R-DOTAP HPV16 peptide formulation confirmed induction of strong in vivo HPV-specific CD8+ cytolyti

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Kopsell, Dean A., David E. Kopsell, and Joanne Curran-Celentano. "Carotenoid and Chlorophyll Pigments in Sweet Basil Grown in the Field and Greenhouse." HortScience 40, no. 4 (2005): 1119D—1119. http://dx.doi.org/10.21273/hortsci.40.4.1119d.

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Therapeutic compounds in herbal crops are gaining recent attention. Sweet basil (Ocimumbasilicum L.) is a popular culinary herbal crop grown for both fresh and dry leaf markets. Recently, basil (unidentified cultivar) was shown to rank highest among spices and herbal crops for xanthophylls carotenoids. This class of carotenoids is associated with decreased risks of certain cancer and age-related eye diseases. The research goal for the current study was to characterize the concentrations of nutritionally important carotenoid pigments among popular varieties of basil. Eight cultivars of sweet ba

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Kopsell, Dean A., David E. Kopsell, and Joanne Curran-Celentano. "Carotenoid and Chlorophyll Pigments in Sweet Basil Grown in the Field and Greenhouse." HortScience 40, no. 5 (2005): 1230–33. http://dx.doi.org/10.21273/hortsci.40.5.1230.

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Sweet basil (Ocimum basilicum L.) is a popular culinary herbal crop grown for fresh or dry leaf, essential oil, and seed markets. Recently, basil was shown to rank highest among spices and herbal crops for xanthophyll carotenoids, which are associated with decreased risks of cancer and age-related eye diseases. The research goal for the current study was to characterize the concentrations of nutritionally important carotenoid pigments in popular varieties of basil. Eight cultivars of sweet basil (`Genovese', `Italian Large Leaf', `Nufar', `Red Rubin', `Osmin Purple', `Spicy Bush', `Cinnamon',

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Chauhan, Aman, Susanne M. Arnold, Jianrong Wu, et al. "Clinical efficacy and toxicity data on phase I study of fosbretabulin in combination with everolimus in neuroendocrine tumors." Journal of Clinical Oncology 37, no. 15_suppl (2019): 4114. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.4114.

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4114 Background: Fosbretabulin, a synthetic, water-soluble, phosphorylated prodrug of the natural product combretastatin A4 (CA4P), initially isolated from the bark of the South African bush willow, Combretum caffrum, is the lead compound in a class of agents termed vascular disrupting agents (VDAs). Everolimus, an mTOR inhibitor, is FDA approved for the management of well-differentiated NETs. A Phase I trial combining fosbretabulin and everolimus to determine the recommended Phase II trial dose (RP2D), safety data and early clinical efficacy in metastatic GEPNET patients was conducted. Method

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PETRUT, Georgiana, Sevastita MUSTE, Crina MURESAN, Adriana PAUCEAN, Andruta MURESAN, and Melinda NAGY. "Chemical Profiles and Antioxidant Activity of Black Elder (Sambucus Nigra L.) - A Review." Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Food Science and Technology 74, no. 1 (2017): 9. http://dx.doi.org/10.15835/buasvmcn-fst:11591.

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Introduction: All plant parts of elderberry (leaves, berries, inflorescences, roots, shoots, bark) have a long history of use in herbal remedy or lots of culinary uses, widespread in almost every continent of the world (1). Pro-health properties indicated a role of elderberry products intake in the prevention of cancer and diabetes.Aims: This paper presents an overview of the evaluation of biochemical compounds (sugars, organic acids, total phenolics, antioxidative activity, flavonoids, flavor and volatile compounds), found in flowers, berries and leaves of Sambucus nigra L.Materials and Metho

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Shetty, Priya. "Too busy to have cancer?" Lancet 369, no. 9574 (2007): 1683–84. http://dx.doi.org/10.1016/s0140-6736(07)60764-8.

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Fagan, Johannes J., Vanita Noronha, and Evan Michael Graboyes. "Making the Best of Limited Resources: Improving Outcomes in Head and Neck Cancer." American Society of Clinical Oncology Educational Book, no. 41 (March 2021): 279–89. http://dx.doi.org/10.1200/edbk_320923.

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The overwhelming majority of head and neck cancers and related deaths occur in low- and middle-income countries, which have challenges related to burden of disease versus access to care. Yet the additional health care burden of the COVID-19 pandemic has also impacted access to care for patients with head and neck cancer in the United States. This article focuses on challenges and innovation in prioritizing head and neck cancer care in Sub-Saharan Africa, the Indian experience of value-added head and neck cancer care in busy and densely populated regions, and strategies to optimize the manageme

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Mishra, Gauravi Ashish, Sharmila Pimple, Anil Singal, Vasundhara Kulkarni, Heena Shaikh, and Parishi Majmudar. "O8C.6 Tobacco control and oral cancer screening among public transport bus drivers, conductors and other staff in mumbai, india." Occupational and Environmental Medicine 76, Suppl 1 (2019): A75.1—A75. http://dx.doi.org/10.1136/oem-2019-epi.201.

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IntroductionTobacco is the single most preventable cause of deaths globally. India is the second largest consumer and third largest producer of tobacco. A plethora of tobacco products are consumed. India has highest number of oral cancer cases globally and bears one fourth of the global burden.With the smoke free public places legislation being implemented since 2nd October 2008, smoking is prohibited on public transport bus premises in India. Tobacco addiction is common among the commuters, drivers, conductors and other staff of the public transport department.The present study was conducted

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Nair, S., and K. Nikam. "Unique Partnership to Roll Out Cancer Awareness and Screening Program for High-Risk Population in Maharashtra." Journal of Global Oncology 4, Supplement 2 (2018): 140s. http://dx.doi.org/10.1200/jgo.18.78600.

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Background and context: India is one of the few countries to have National Cancer Control Program and emphasis is given on tobacco related cancers because of high prevalence of such practices in India. As per the Global Adult survey 2016 around 30% of Indian population consume tobacco in any other form. Bus drivers, conductors and support staff of two leading public transport companies will be targeted by Indian Cancer Society as they are among high risk population with huge percentage of employees addicted with tobacco. Through this unique partnership, Indian Cancer Society (ICS) will promote

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Ledford, Heidi. "Therapeutic cancer vaccine survives biotech bust." Nature 519, no. 7541 (2015): 17–18. http://dx.doi.org/10.1038/nature.2015.16990.

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Paul, Akshoy Ranjan, Firoz Khan, Anuj Jain, and Suvash Chandra Saha. "Deposition of Smoke Particles in Human Airways with Realistic Waveform." Atmosphere 12, no. 7 (2021): 912. http://dx.doi.org/10.3390/atmos12070912.

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Exposure to toxic particles from smoke generated either from bush fire, stable burning, or direct smoking is very harmful to our health. The tiny particles easily penetrate deep into the lungs after exposure and damage the airways. Tobacco smoking causes the direct emission of 2.6 million tons of CO2 and 5.2 million tons of methane annually into the atmosphere. Nevertheless, it is one of the significant contributors to various respiratory diseases leading to lung cancer. These particles’ deposition in the human airway is computed in the present article for refining our understanding of the adv

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MACNEIL, JANE SALODOF. "Cancer Surgery Survival Better at Busy Hospitals." Internal Medicine News 39, no. 10 (2006): 62. http://dx.doi.org/10.1016/s1097-8690(06)73563-6.

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Tusanti, Iin, Andrew Johan, and RA Kisdjamiatun. "Sitotoksisitas in vitro ekstrak etanolik buah parijoto (Medinilla speciosa, reinw.ex bl.) terhadap sel kanker payudara T47D." Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) 2, no. 2 (2014): 53–58. http://dx.doi.org/10.14710/jgi.2.2.53-58.

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Background: Several studies focused on phytochemical as agents of cancer prevention and co-chemotherapy. One of Indonesian plant which has edible fruit but it hasn’t been completely explored is Medinilla speciosa (Reinw.ex Bl.). Objective : The aim of this study is to examine the cytotoxic activity (IC50 value) of Medinilla speciosa (Reinw.ex Bl.) fruit ethanolic extract. Methods : Medinilla speciosa (Reinw.ex Bl.) fruit ethanolic extract was used in this study. The cytotoxic activity was investigated in vitro on human breast cancer T47D cell-line. The cells viability were assessed using MTT c

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