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1

Hammersmith, KJ, JR DePalo, PS Casamassimo, JK MacLean, and J. Peng. "Silver Diamine Fluoride and Fluoride Varnish May Halt Interproximal Caries Progression in the Primary Dentition." Journal of Clinical Pediatric Dentistry 44, no. 2 (2020): 79–83. http://dx.doi.org/10.17796/1053-4625-44.2.2.

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Objective: The study described the incidence of interproximal caries arrest following SDF and fluoride varnish application in the primary dentition. Study design: A retrospective analysis of dental records including radiographs was conducted for interproximal dental caries in pediatric patients treated with SDF applied with woven floss. Bitewing radiographs and ICCMS™ radiographic scoring criteria were used to assess caries depth in primary teeth at baseline and then at 12-month follow-up examination. Results: This study included 185 interproximal carious lesions in 131 patients trea
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Phonghanyudh, Araya, Duangporn Duangthip, Sirinan Mabangkhru, and Varangkanar Jirarattanasopha. "Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial." International Journal of Environmental Research and Public Health 19, no. 15 (2022): 8992. http://dx.doi.org/10.3390/ijerph19158992.

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Background: There is limited information on the effectiveness of 38% silver diamine fluoride (SDF) in managing enamel caries. Objective: This study aimed to compare effectiveness of 38% SDF and 5% Sodium fluoride (NaF) varnish in arresting enamel caries in young children when applied semiannually over 18 months. Methods: A randomized controlled trial was conducted on children aged 1–3 years who had at least one active carious surface. They were allocated into two groups: Group 1 (38% SDF) and Group 2 (5% NaF varnish). Visual-tactile examination was used to assess extent of carious lesions. Ena
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Timms, Laura, Chris Deery, Claire Stevens, and Helen Rodd. "COVID-2019 – Time to Use Silver Diamine Fluoride for Caries Arrest in General Dental Practice?" Dental Update 47, no. 8 (2020): 662–68. http://dx.doi.org/10.12968/denu.2020.47.8.662.

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Silver diamine fluoride (SDF) is applied topically to arrest caries and has an increasing evidence base to support its efficacy, both in the primary dentition and to arrest root caries in older patients. It can be used as a non-aerosol generating procedure and is a simple technique. It has a side-effect of discolouring caries black, a factor which requires discussion with patients and their carers prior to application. Due to its efficacy and simplicity, it is a useful intervention for the management of caries. CPD/Clinical Relevance: Caries is a common condition in the UK, and silver diamine
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Thylstrup, A., C. Bruun, and L. Holmen. "In Vivo Caries Models-Mechanisms for Caries Initiation and Arrestment." Advances in Dental Research 8, no. 2 (1994): 144–57. http://dx.doi.org/10.1177/08959374940080020401.

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The effects of intra-oral mechanical forces on caries initiation, progression, and arrestment are evaluated by examination of different in vivo caries models. The models are grouped in four categories: (1) a population study, (2) short-term clinical trials, (3) clinical experiments, and (4) controlled clinical observations. Taken together, these in vivo studies convincingly demonstrate that partial or total elimination of the intra-oral mechanical forces operating during mastication or toothbrushing leads to evolution of cariogenic plaque, resulting in localized carious enamel dissolution. In
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Goel, Pallavi, Vikram R, Adarsha M S, and Sudhanva M E. "Silver Diamine Fluoride – A “Silver-fluoride Bullet” for Dental Caries." RGUHS Journal of Dental Sciences 13, no. 4 (2021): 279–82. http://dx.doi.org/10.26715/rjds.13_4_11.

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Dental caries is one of the most prevalent diseases across the globe, affecting all age groups. Various public health measures like water fluoridation have been started to control the spread of caries, especially among children. But these intervention methods are inaccessible to people in some parts of the world. Thus, a product called Silver Diamine Fluoride was introduced, which can help arrest carious lesions at an early stage. It is a beneficial aid for caries arrest in both primary and permanent teeth. Also, can be used for arresting root caries. Thus, the objective of this review article
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Nyvad, B., J. M. Ten Cate, and O. Fejerskov. "Arrest of Root Surface Caries in situ." Journal of Dental Research 76, no. 12 (1997): 1845–53. http://dx.doi.org/10.1177/00220345970760120701.

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Iswar, Dishika, Arun Kumar Sajjanar, Milind Wasnik, Niharika Gawod, Partima Kolekar, and Sahil Bumdele. "Silver diamine fluoride for managing carious lesions: A literature review." Archives of Dental Research 11, no. 2 (2021): 118–22. http://dx.doi.org/10.18231/j.adr.2021.020.

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Though the prevalence and the severity of dental caries is decreased in past few years, still children from low socioeconomical status in many industrialized or developing countries are still suffering from ill-effects of dental caries. The antimicrobial effect of silver compounds has been proven by the 100-year-old application of silver compounds. Silver diamine fluoride (SDF) has been used to arrest dental caries during 1970s in Japan, but it was not exposed much to other parts of the world. Today in many countries a 38% (44,800 ppm fluoride) SDF solution is commonly used to arrest caries an
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Malin, Ashley J., Zhilin Wang, Durdana Khan, and Sarah L. McKune. "The Potential Systemic Role of Diet in Dental Caries Development and Arrest: A Narrative Review." Nutrients 16, no. 10 (2024): 1463. http://dx.doi.org/10.3390/nu16101463.

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Current conceptualizations of dental caries etiology center primarily on the local role of sugar, starch, or other fermentable carbohydrates on tooth enamel demineralization—a well-established and empirically supported mechanism. However, in addition to this mechanism, studies dating back to the early 1900s point to an important systemic role of diet and nutrition, particularly from pasture-raised animal-source foods (ASF), in dental caries etiology and arrest. Findings from animal and human studies suggest that adherence to a diet high in calcium, phosphorus, fat-soluble vitamins A and D, and
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Rajakumari, T. N., G. Thiruvenkadam, D. Vinola, and M. Kruthika. "Silver diamine fluoride – A review." Journal of Academy of Dental Education 6 (December 29, 2020): 5–10. http://dx.doi.org/10.25259/jade_3_2020.

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Untreated dental caries remains a challenge in young children and adolescents. Invasive treatments in very young children and children with special health care needs require advanced pharmacological behaviour management strategies. A minimally invasive treatment modality to arrest caries is by application of 38% Silver Diamine Fluoride (SDF). Besides its efficacy to arrest decay, SDF is favoured by its inexpensiveness. This review enlightens the evolution, historical background, mechanism of action, clinical considerations, advantages and disadvantages of Silver Diamine Fluoride.
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Raju, M. Vijaya, Vinay Darshan, A. P. Nirmal Raj, Sanajay Kumar, and S. Revathi. "Atraumatic Restorative Treatment: A Short Review." Malaysian Journal of Medical and Biological Research 3, no. 1 (2016): 41–42. http://dx.doi.org/10.18034/mjmbr.v3i1.403.

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In certain patients for whom there is increased demand for the treatment needs such as rural areas, an attempt has been made to improve the status of the oral health by use of the procedures which arrest the destructive dental caries process and alter microorganisms to favorable condition. This is called as atraumatic restorative treatment. It consists of low-cost and simplified technique using only hand instruments for the removal of the carious lesion and to arrest the progression of the caries. Since its discovery it has becoming an important treatment modality for the oral health care work
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Chai, Hollis Haotian, Sakura Kiuchi, Ken Osaka, Jun Aida, Chun-Hung Chu, and Shiqian (Sherry) Gao. "Knowledge, Practices and Attitudes towards Silver Diamine Fluoride Therapy among Dentists in Japan: A Mixed Methods Study." International Journal of Environmental Research and Public Health 19, no. 14 (2022): 8705. http://dx.doi.org/10.3390/ijerph19148705.

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In 2021, the World Health Organization included silver diamine fluoride (SDF) as an essential medicine to manage caries in adults and children. SDF was developed in the 1960s, but its use for children became unpopular in Japan because of the decline and low prevalence of early childhood caries. This mixed methods study explored the knowledge, practices and attitudes towards SDF therapy among dentists promoting fluoride use in Japan. It also investigated senior dentists’ perceptions of SDF therapy in Japan. The quantitative study invited all 173 members of the largest organisation promoting flu
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Gyawali, Namrata, Sunanda Sundas, Barun Kumar Sah, and Neha Dhakal. "Efficacy of Silver Diamine Fluoride in Arresting Dental Caries in Primary Teeth in Patient Visiting Tertiary Hospital of Kathmandu." Journal of College of Medical Sciences-Nepal 19, no. 4 (2023): 412–18. http://dx.doi.org/10.3126/jcmsn.v19i4.55243.

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IntroductionCarious lesions can both be prevented and arrested using fluoride-based materials. This study was done to evaluate and compare the efficacy of silver diamine fluoride in arresting dental caries at different frequencies of applications. MethodsThis experimental study was conducted among ten preschool children of 3-5 years old with seventy-four active carious lesions taking teeth as a sample unit. Children were randomly allocated into two intervention groups: Group 1— application of 38% silver diamine fluoride solution atthree consecutive weeks and Group 2— three applications of 38%
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Ruff, Ryan Richard, Tamarinda Barry-Godín, and Richard Niederman. "Effect of Silver Diamine Fluoride on Caries Arrest and Prevention." JAMA Network Open 6, no. 2 (2023): e2255458. http://dx.doi.org/10.1001/jamanetworkopen.2022.55458.

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ImportanceDental caries is the most common global childhood disease. To control caries, the Centers for Disease Control and Prevention recommends school-based caries prevention, and the World Health Organization lists glass ionomer cement and silver diamine fluoride as essential medicines for oral disease.ObjectiveTo determine the noninferiority of silver diamine fluoride with fluoride varnish vs traditional glass ionomer sealants with fluoride varnish after 2 years when provided to children via a school-based health care program.Design, Setting, and ParticipantsThe CariedAway study is an ongo
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Matharu, Aavan Kaur, and Isabel Cristina Olegário. "Are GIC sealants as effective as composite sealants in caries prevention?" Dental Update 51, no. 2 (2024): 102–8. http://dx.doi.org/10.12968/denu.2024.51.2.102.

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Fissure sealants (FS) are micro-invasive procedures that have proved to be effective in caries prevention in caries-free, first permanent molars. Within high-caries risk individuals, fissure sealants arrest the caries process in early caries lesions stages. Composite resin (CR) sealants have been recognized as the gold standard FS material; however, new evidence has emerged in relation to GIC sealants in their applicability and longevity. This review provides evidence-based information supporting the effectiveness of GIC sealants in caries prevention in comparison to CR sealants, by assessing
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Mushtaha, Dr Sahar. "The Use of Silver Diamine Flouride in Caries Arrest: A Review Article." Scholars Journal of Dental Sciences 11, no. 04 (2024): 40–46. http://dx.doi.org/10.36347/sjds.2024.v11i04.001.

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Interest in the use of silver diamine fluoride (SDF) has been growing. SDF has been used as an alternative treatment for caries prevention and arrest. In 2014, SDF was approved by the US Food and Drug Administration as a treatment for dentinal sensitivity. A CDT code adopted by FDA in 2016 is D1354—interim caries arresting medicament application: “Conservative treatment of an active, non-symptomatic carious lesion by topical application of a caries arresting or inhibiting medicament and without mechanical removal of sound tooth structure”.
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Zaffarano, Luciano, Claudia Salerno, Guglielmo Campus, et al. "Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic Review and Metanalysis." International Journal of Environmental Research and Public Health 19, no. 19 (2022): 12917. http://dx.doi.org/10.3390/ijerph191912917.

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A systematic review and meta-analysis were carried out to evaluate the efficacy of silver diamine fluoride (SDF) in controlling caries progression in cavitated primary molars. A search for randomized and non-randomized trials with follow-up > 6 months was performed using PubMed, Scopus and Embase. The Cochrane risk of bias tools were used for the quality assessment. The success rate and odds ratios were chosen to calculate the effect size for the meta-analysis. A total of 792 papers were identified and 9 were selected. A high variability regarding SDF application protocol was found; otherwi
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Geethu, P. N., N. Suvedha, Allen Anil Kurien, Yadav Chakravarthy, and Vyapaka Pallavi. "Demineralization and remineralization in restorative dentistry." Journal of Academy of Dental Education 9 (June 14, 2023): 28–30. http://dx.doi.org/10.25259/jade_15_2022.

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The purpose of caries remineralization therapy is to arrest or reverse the caries process. This paper describes the importance of calcium and phosphate ions in tooth and bone health. The processes through which the demineralization–remineralization process occurs in both teeth and bone, as well as emerging therapies/ technologies that can reverse demineralization or promote remineralization, are thoroughly reviewed.
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Agarwal, Deepti, Priyanka Sambhajirao Machale, and Sahana Hegde-Shetiya. "The Incipient Caries." Journal of Contemporary Dentistry 3, no. 1 (2013): 20–24. http://dx.doi.org/10.5005/jp-journals-10031-1029.

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ABSTRACT Caries lesion progression is highly dynamic process characterized by alternating periods of dissolution and redeposition of minerals in the dental hard tissue. When outcome of these processes overtime is a net loss of mineral, a caries lesion develops or progresses. However, when redeposition of mineral predominates, the result may be arrest of lesion progression or remineralization. Clinical observations suggest that caries lesion can be arrested at any stage of lesion development provided that clinically plaque-free conditions are maintained. Hence, the profession must become aware
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Tharani., T1, Chawla2 Twinkle, Prasadh3 Lakshmi, Singhania4 Rashika, and Shah5 Sakshi. "Silver Diamine Fluoride: A Magic Stain- A Review." Heal Talk- A Journal of Clinical Dentiostry 15, no. 6 (2023): 27–34. https://doi.org/10.5281/zenodo.8351244.

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The use of a topical fluoride solution, specifically silver diamine fluoride (SDF), in dental treatment is gaining popularity. SDF has been utilized as a caries arresting and anti-hypersensitivity agent in various Asian countries, including Japan and China. The Food and Drug Administration recently approved it.In the United States, it is approved by the Food and Drug Administration as a fluoride to treat hypersensitive teeth. Topical use of SDF is a noninvasive, rapid, and easy treatment. Laboratory investigations and clinical trials have shown that SDF is more effective than other fluoride tr
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Mei, M. L., E. C. M. Lo, and C. H. Chu. "Arresting Dentine Caries with Silver Diamine Fluoride: What’s Behind It?" Journal of Dental Research 97, no. 7 (2018): 751–58. http://dx.doi.org/10.1177/0022034518774783.

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Unlike other fluoride-based caries preventive agents, silver diamine fluoride (SDF) can simultaneously prevent and arrest coronal and root dentine caries. The profound clinical success of SDF has drawn many clinicians and researchers to study the mechanism of SDF in arresting dentine caries. This critical review discusses how silver and fluoride contribute to caries arrest, in terms of their effects on bacteria as well as on the mineral and organic content of dentine. Silver interacts with bacterial cell membrane and bacterial enzymes, which can inhibit bacterial growth. Silver can also dope i
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Abudrya, Mohamed, Christian H. Splieth, Mhd Said Mourad, and Ruth M. Santamaría. "Efficacy of Different Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth." Medicina 59, no. 11 (2023): 2042. http://dx.doi.org/10.3390/medicina59112042.

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Background and Objectives: This prospective, comparative, double-cohort study aimed to compare the efficacy of silver diamine fluoride and potassium iodide (38% SDF+KI; Riva Star®) with sodium fluoride varnish (5% NaF; Duraphat®) in hypersensitive carious lesions in primary teeth to evaluate caries arrest and hypersensitivity relief. Materials and Methods: This study included thirty 2–5-year-olds (mean age = 3.67 ± 1.06 years; 16 males and 14 females) who required a desensitizing treatment for hypersensitive carious defects with visible dentin. A total of 15 of the participants were consecutiv
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Butrón Téllez Girón, Claudia, Juan F. Hernández Sierra, Idania DeAlba‐Montero, María de los A. Urbano Peña, and Facundo Ruiz. "Therapeutic Use of Silver Nanoparticles in the Prevention and Arrest of Dental Caries." Bioinorganic Chemistry and Applications 2020 (August 12, 2020): 1–7. http://dx.doi.org/10.1155/2020/8882930.

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Dental caries is one of the major diseases of the oral cavity affecting humans worldwide. Different alternatives have been used for its control, but its incidence and prevalence are still high. On the other hand, silver has been used for centuries due to its antimicrobial properties. With advances in nanotechnology, the use and research in nanomaterials has increased, recently, and silver nanoparticles have become an essential part of the dental practice, giving materials physical and chemical improvements in their properties, used for their antibacterial capacity preventing and arresting dent
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Fung, M. H. T., D. Duangthip, M. C. M. Wong, E. C. M. Lo, and C. H. Chu. "Randomized Clinical Trial of 12% and 38% Silver Diamine Fluoride Treatment." Journal of Dental Research 97, no. 2 (2017): 171–78. http://dx.doi.org/10.1177/0022034517728496.

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This 30-mo randomized clinical trial compared the effectiveness of 2 concentrations (12% or 38%) of silver diamine fluoride (SDF) and 2 periodicity of application (once or twice a year) in arresting cavitated dentin caries in primary teeth. Children aged 3 to 4 y who had at least 1 active cavitated caries lesion were enrolled and randomly allocated into 4 groups for intervention. Group 1 had 12% SDF applied annually (every 12 mo), group 2 had 12% SDF applied semiannually (every 6 mo), group 3 had 38% SDF applied annually, and group 4 had 38% SDF applied semiannually. Clinical examinations were
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Kumar, Neeraj, and Richa Kumari. "Historical background and clinical implications of silver diamine fluoride in dentistry: A narrative review." BOHR International Journal of Current Research in Dentistry 1, no. 1 (2022): 49–53. http://dx.doi.org/10.54646/bijcrid.2022.10.

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Dental caries is a chronic, irreversible disease affecting preschool children worldwide. As the frequency of dental caries has steadily declined over the past few years, children from low socioeconomic backgrounds still have higher rates of dental caries, and still have a higher prevalence in developing countries. Though the role of fluoride in dental caries prevention has been scientifically proven, the antimicrobial effect of silver compounds to treat various infections has been postulated. However, 38% silver diamine fluoride (SDF) solution is currently used to arrest dental caries, and as
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Gao, S. S., D. Duangthip, M. C. M. Wong, E. C. M. Lo, and C. H. Chu. "Randomized Trial of Silver Nitrate with Sodium Fluoride for Caries Arrest." JDR Clinical & Translational Research 4, no. 2 (2019): 126–34. http://dx.doi.org/10.1177/2380084418818482.

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Objectives: The aim of this noninferiority double-blind randomized clinical trial was to compare the effectiveness of the topical semiannual application of a 25% silver nitrate (AgNO3) solution followed by a 5% sodium fluoride (NaF) varnish with that of a 38% silver diamine fluoride (SDF) solution in arresting caries among preschool children. Methods: Healthy 3-y-old children with active dentine carious lesions were randomly allocated to 2 groups via computer-generated random numbers. Lesions in group A received applications of a 25% AgNO3 solution followed by a 5% NaF varnish semiannually (ev
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Pradeepika Liyana Arachchige, A., Amina Sultan, and Chandra Herath. "Silver diamine fluoride for early childhood caries- A boon for dentists during COVID-19 pandemic." International Journal of Oral Health Dentistry 7, no. 3 (2021): 161–65. http://dx.doi.org/10.18231/j.ijohd.2021.033.

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Early Childhood Dental Caries (ECC) is a global burden. Management protocols of a disease are changing constantly with the improving knowledge of the disease, new materials, and treatment strategies. Clinical studies have confirmed the use of Silver Diamine Fluoride (SDF) is an effective and efficient caries arrest and a prevention therapy. It is a simple, safe, and quick treatment option for carious deciduous teeth. More importantly, caries removal is not indicated before the application which makes the topical application of SDF solution a good alternative in the management of ECC during the
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Elgezawi, Moataz, Rasha Haridy, Moamen A. Abdalla, Katrin Heck, Miriam Draenert, and Dalia Kaisarly. "Current Strategies to Control Recurrent and Residual Caries with Resin Composite Restorations: Operator- and Material-Related Factors." Journal of Clinical Medicine 11, no. 21 (2022): 6591. http://dx.doi.org/10.3390/jcm11216591.

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This review addresses the rationale of recurrent and/or residual caries associated with resin composite restorations alongside current strategies and evidence-based recommendations to arrest residual caries and restrain recurrent caries. The PubMed and MEDLINE databases were searched for composite-associated recurrent/residual caries focusing on predisposing factors related to materials and operator’s skills; patient-related factors were out of scope. Recurrent caries and fractures are the main reasons for the failure of resin composites. Recurrent and residual caries are evaluated differently
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da Costa Rosa, Thamirys, Aline de Almeida Neves, M. Andrea Azcarate-Peril, et al. "The bacterial microbiome and metabolome in caries progression and arrest." Journal of Oral Microbiology 13, no. 1 (2021): 1886748. http://dx.doi.org/10.1080/20002297.2021.1886748.

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Alves, L. S., J. E. A. Zenkner, M. B. Wagner, N. Damé-Teixeira, C. Susin, and M. Maltz. "Eruption Stage of Permanent Molars and Occlusal Caries Activity/Arrest." Journal of Dental Research 93, no. 7_suppl (2014): 114S—119S. http://dx.doi.org/10.1177/0022034514537646.

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Houpt, Milton. "Topical Application of Silver Diamine Fluoride may Arrest Dental Caries." Journal of Evidence Based Dental Practice 11, no. 1 (2011): 54–55. http://dx.doi.org/10.1016/j.jebdp.2010.11.011.

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Akah, Mai Mamdouh, Laila Akmal Elokaly, Heba Salah Eldien Hamza, and Essam Abdelhafez Naguib. "Clinical and radiographic evaluation of deep occlusal carious molars treated with partial caries removal with and without using silver diamine fluoride (SDF) + Potassium iodide (KI) prior to resin composite restoration: A randomized clinical trial." International Journal of Oral Health Dentistry 10, no. 3 (2024): 201–8. http://dx.doi.org/10.18231/j.ijohd.2024.036.

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Dental caries is considered the most widespread human disease. Caries arrest therapy is now being marketed as a component of the essential dental care regimen. Researchers and dental clinicians are paying close attention to silver diamine fluoride (SDF), one of the antibacterial agents, for its ability to stop active caries. This study aimed to evaluate the effect of SDF+KI in maintaining pulp health, dentin bridge formation and remineralization after partial caries removal in permanent teeth that were evaluated clinically and radiographically after different follow-up periods.: Eighty teeth h
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Done, Vasanthi, Saraswathi Kanaparthi, Vinod Bandela, Mohammad Khursheed Alam, and Pradeep Muralidhar MV. "Silver Diamine Fluoride – the magic bullet! Is it really a magic alternative in caries management." Bangladesh Journal of Medical Science 23, no. 4 (2024): 993–98. http://dx.doi.org/10.3329/bjms.v23i4.76508.

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The goal of modern dentistry is to treat cavitated or non-cavitated teeth through non-invasive remineralization to prevent further progression of caries and to improve the function of teeth. Many preventive interventions have been put forward as an alternative to conventional restorative procedures; silver diamine fluoride (SDF) is one amongst them. SDF can arrest progression of carious lesion at a concentration of 12% and 38% preventing further caries growth. The aim of this paper is to consider whether SDF is really a magic alternative in caries management or not. Bangladesh Journal of Medic
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Abdulelah Abdulrahmn Almallah, Lubna. "Topical Effect of Silver Diamine Fluoride in Preventing and Arresting Root Caries in Elderly Patients." Mustansiria Dental Journal 17, no. 1 (2024): 50–57. http://dx.doi.org/10.32828/mdj.v17i1.1015.

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Aim of the study: The purpose of the present investigation was to see how efficient silver diamine fluoride (SDF) solution treatment to prevent dental root caries.
 Materials and method: This research was done at Iraq's geriatric facilities. Forty seniors with active caries lesions were fortuitously assigned into two groups: Group 1 (placebo control)—doubles Twice-Annual treatment with soda water; Group 2—Doubles Twice-Annual treatment with silver diamine fluoride solution.
 Results: After 18 months, the arrest rates of root caries were 28 percent in group1 (control) and 88 percent g
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Parul, Mhaski, Mangla Ritu, Dua Parminder, Vyas Divya, and Neha . "EVALUATING THE EFFICACY OF 38% SDF VS 5% NAF VS APF GEL IN ARRESTING DENTAL CARIES AND REDUCING BACTERIAL ACTIVITY: AN IN-VIVO STUDY." International Journal of Advanced Research 12, no. 07 (2024): 1287–96. http://dx.doi.org/10.21474/ijar01/19175.

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Background: The study was formulated to compare the efficacy of 38% SDF as a caries arresting agent as well as antibacterial and antiplaque agent in vivo with 5% sodium fluoride varnish (NaF) and 1.23% acidulated phosphate fluoride (APF) gel. Study Design: Total of 74 children aged 6-9 years (boys = 34, girls = 40) who had active caries with dmfs/DMFS score equal to or more than 1 were included in the study for a period of 12 months. Children were divided into three different groups-Group 1: 38%SDF Group 2: 5% fluoride varnish and Group 3: 1.23% APF gel. Fluoride application was done at baseli
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Therathil, Sona G., and Prasad Veeravenkata Kakarla. "Comparison of Effectiveness of Two Silver Compounds in Arresting Caries in Outreach Programs in Karnataka." Journal of Indian Association of Public Health Dentistry 21, no. 3 (2023): 276–80. http://dx.doi.org/10.4103/jiaphd.jiaphd_122_22.

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Context: Silver compounds have been used clinically in dentistry and have effectively arrested dental caries. However, their potential use in community outreach programs has not been explored. Aims: This study aims to investigate the effectiveness of two silver compounds, silver diamine fluoride (SDF) and silver nitrate (SN), in arresting caries in deciduous teeth when used in outreach programs. Settings and Design: This is a randomized trial with a split mouth design done in three primary schools in Dharwad city. Subjects and Methods: This study was conducted among 174 teeth in 58 subjects be
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Yon, Madeline Jun Yu, Sherry Shiqian Gao, Kitty Jieyi Chen, Duangporn Duangthip, Edward Chin Man Lo, and Chun Hung Chu. "Medical Model in Caries Management." Dentistry Journal 7, no. 2 (2019): 37. http://dx.doi.org/10.3390/dj7020037.

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The current mode of dental caries management mainly operates through irreversible and symptomatic treatment by means of drilling and filling, while caries prevention is largely overlooked or omitted. Focus should be redirected through a medical model towards elimination of the disease through tackling its causes and risk factors to address current and future caries initiation. Caries is the demineralisation of dental hard tissues by bacterial acids when periodically exposed to fermentable carbohydrates. The medical model of caries management is a philosophy that steers sustainable caries manag
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Cheng, Anthony Yihong, Jieyi Chen, Faith Miaomiao Zheng, Duangporn Duangthip, and Chun Hung Chu. "Arresting Early Childhood Caries with Silver Diamine Fluoride Gel Among Preschool Children: Protocol for a Randomised Clinical Trial." Dentistry Journal 12, no. 12 (2024): 419. https://doi.org/10.3390/dj12120419.

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Background: The World Health Organisation (WHO) included silver diamine fluoride (SDF) in the WHO Model List of Essential Medicines for the management of early childhood caries. SDF is typically available as a 38% aqueous solution, which is watery to apply. A 38% SDF gel has recently been developed, but its caries-arrest effectiveness remains unsubstantiated. The objective of this study is to determine whether the efficacy of a 38% SDF gel is non-inferior to a 38% SDF solution in arresting early childhood caries. Methods: This is a 30-month, randomised, active-controlled, parallel-group non-in
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38

Crystal, Yasmi O. "Silver diamine fluoride (SDF): its role in caries management." Dental Update 46, no. 11 (2019): 1016–22. http://dx.doi.org/10.12968/denu.2019.46.11.1016.

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Silver diamine fluoride (SDF) combines the antibacterial properties of silver and the remineralizing actions of fluoride in an alkaline solution that creates an unfavourable environment for collagen degradation. Clinical trials have proven the efficacy of SDF as a caries-arresting agent in primary teeth and root caries in the elderly. It is minimally invasive, inexpensive, safe and easy to apply, but a sign of arrest is the dark discoloration of the lesions where it is applied. SDF provides clinicians with a valuable additional tool in their armamentarium for caries management that aims to sto
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Alresheedi, Bandar, and Syed Shujaulla. "Resin infiltrants - A review." International Archives of Integrated Medicine 12, no. 2 (2025): 20–25. https://doi.org/10.5281/zenodo.14954982.

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Tooth decay is a microbial, infectious and multi-factorial disease and is still globally a highly prevalent pathology. The management of Dental caries has dramatically changed in recent years, evolving from the traditional restorative treatment approach to a preventive approach, non-invasion or minimal invasion. Minimal intervention focuses on preventive or non-surgical methods to preserve dental hard tissues is a part of modern dentistry, this avoids any unwanted sacrifice of tooth structure, and also enhances the life of the tooth. Noninvasive management of non-cavitated caries lesions inclu
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40

Peters, M. C., A. R. Hopkins, L. Zhu, and Q. Yu. "Efficacy of Proximal Resin Infiltration on Caries Inhibition: Results from a 3-Year Randomized Controlled Clinical Trial." Journal of Dental Research 98, no. 13 (2019): 1497–502. http://dx.doi.org/10.1177/0022034519876853.

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This study reports 3-y outcomes of a split-mouth randomized clinical trial. Resin infiltration’s capacity to arrest caries lesion progression in noncavitated proximal lesions is affirmed. Forty-two consented young adults, blinded to tooth surface allocation, were treated with resin infiltration on 1 randomly selected surface and concurrently experienced a mock infiltration procedure on another. Both treatments were provided as an adjunct to the currently accepted standard-of-care regimen (periodic prophylaxis and serial fluoride varnish applications) appropriate for the management of high cari
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41

Elbahary, Shlomo, Shiran Aharonian, Hanaa Azem, Benjamin Peretz, Olga Mostinski, and Sigalit Blumer. "Bacterial Colonization and Proliferation in Primary Molars following the Use of the Hall Technique: A Confocal Laser Scanning Microscopy Study." Children 10, no. 3 (2023): 457. http://dx.doi.org/10.3390/children10030457.

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Restorative dentistry aims to create a favorable environment to arrest caries with minimal operative intervention. The Hall technique (HT) involves the seating and cementation of stainless steel crowns (SSC) on primary molars without any tooth preparation, caries removal, or local anesthesia. In this manner, it entombs bacteria and arrests caries’ progress. We compared bacterial distribution and quantity among primary molars affected with caries and restored with SSC using the HT (n = 10), the conventional technique (CT; n = 10), or not restored at all (control; n = 10). The teeth were contami
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42

Duffin, Steven R., and Marcus L. Duffin. "Use of Fluoride and Silver Ion Compounds in Three International School Based Oral Health Programs – A Case Report." Journal of Public Health International 3, no. 2 (2020): 1–11. http://dx.doi.org/10.14302/issn.2641-4538.jphi-20-3541.

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Untreated dental caries in children is one of the most common diseases and largest public health problems in the world. A novel caries management program, using 50% silver nitrate, 38% silver diamine fluoride, and 5% sodium fluoride varnish, was developed at Shoreview Dental, LLC, a private dental practice in Oregon USA, and then introduced into schools in Ecuador, Ghana, and Bolivia. Cavitated carious lesions were treated with 50% silver nitrate, followed by covering with 5% sodium fluoride varnish, three times over two weeks for 165 children in Ecuador at initial assessment, 3 months, and 6
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43

Soni, Abhishek, Sanchit Paul, and Priyanka Sachdeva. "Silver diamine fluoride as a minimally invasive and aerosol free approach in pediatric dentistry: An extensive case series." Contemporary Pediatric Dentistry 2, no. 2 (2021): 42–54. http://dx.doi.org/10.51463/cpd.2021.51.

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The current pandemic of COVID-19 warrants a repeal from conventional dentistry to an aerosol free, minimally invasive yet maximally effective clinical approach. Silver diamine fluoride (SDF) is an established modality for caries arrest in children fulfilling all the above. This extensive 25 case series highlights various clinical situations in which SDF was successfully used in children between 1-12 years of age with asymptomatic carious lesions of ICDAS score 2 or more in primary and permanent teeth. Primary outcome measure was caries arrest in the form of the hard and shiny lesion with no/mi
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Duangthip, D., M. C. M. Wong, C. H. Chu, and E. C. M. Lo. "Caries arrest by topical fluorides in preschool children: 30-month results." Journal of Dentistry 70 (March 2018): 74–79. http://dx.doi.org/10.1016/j.jdent.2017.12.013.

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Gold, Jaana. "Limited Evidence Links Silver Diamine Fluoride and Caries Arrest in Children." Journal of Evidence Based Dental Practice 17, no. 3 (2017): 265–67. http://dx.doi.org/10.1016/j.jebdp.2017.06.012.

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Fung, M. H. T., D. Duangthip, M. C. M. Wong, E. C. M. Lo, and C. H. Chu. "Arresting Dentine Caries with Different Concentration and Periodicity of Silver Diamine Fluoride." JDR Clinical & Translational Research 1, no. 2 (2016): 143–52. http://dx.doi.org/10.1177/2380084416649150.

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Different regimens of silver diamine fluoride (SDF) have been used to manage early childhood caries. So far, there is limited information regarding the concentrations and frequency of applications for effective caries control in primary teeth. This study aimed to compare the efficacy of 2 commercially available SDF solutions at preprepared concentrations of 38% and 12% when applied annually or biannually over 18 mo in arresting dentine caries in primary teeth. This randomized double-blinded clinical trial recruited kindergarten children aged 3 to 4 y who had at least 1 tooth with dentine carie
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47

Dai, Lin Lu, May Lei Mei, Chun Hung Chu, and Edward Chin Man Lo. "Mechanisms of Bioactive Glass on Caries Management: A Review." Materials 12, no. 24 (2019): 4183. http://dx.doi.org/10.3390/ma12244183.

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This review investigates the mechanisms of bioactive glass on the management of dental caries. Four databases (PubMed, Web of Science, EMBASE (via Ovid), Medline (via Ovid)) were systematically searched using broad keywords and terms to identify the literature pertaining to the management of dental caries using “bioactive glass”. Titles and abstracts were scrutinized to determine the need for full-text screening. Data were extracted from the included articles regarding the mechanisms of bioactive glass on dental caries management, including the aspect of remineralizing effect on enamel and den
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48

Fu, Yipeng, Manikandan Ekambaram, Kai Chun Li, Ya Zhang, Paul R. Cooper, and May Lei Mei. "In Vitro Models Used in Cariology Mineralisation Research—A Review of the Literature." Dentistry Journal 12, no. 10 (2024): 323. http://dx.doi.org/10.3390/dj12100323.

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Background: Dental caries remains a significant global health problem. One of the fundamental mechanisms underlying the development and progression of dental caries is the dynamic process of demineralisation/remineralisation. In vitro models have played a critical role in advancing our understanding of this process and identifying potential interventions to prevent or arrest dental caries. This literature review aims to provide a structured oversight of in vitro mineralisation models which have been used to study the tooth demineralisation/remineralisation process. Methods: Publications from 2
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Silva da Silveira, Ana Daniela, Boniek Castillo Dutra Borges, Hugo de Almeida Varela, Kenio Costa de Lima, and Isauremi Vieira de Assunção Pinheiro. "Progression of non-cavitated lesions in dentin through a nonsurgical approach: a preliminary 12-month clinical observation." European Journal of Dentistry 06, no. 01 (2012): 034–42. http://dx.doi.org/10.1055/s-0039-1698928.

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ABSTRACTObjective: Considering the minimally invasive approach to dentistry, the scientific community has focused on non-invasive treatments for caries lesions. The aim of this study was to evaluate the efficacy of a nonsurgical approach to arrest occlusal non-cavitated dentin lesions through glass ionomer sealing.Methods: In this controlled clinical trial, 51 teeth with clinically non-cavitated occlusal caries radiographically located beneath the enamel-dentine junction (radiolucent area) were selected among patients presenting a moderate to high risk of caries. The teeth were randomly divide
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Llodra, J. C., A. Rodriguez, B. Ferrer, V. Menardia, T. Ramos, and M. Morato. "Efficacy of Silver Diamine Fluoride for Caries Reduction in Primary Teeth and First Permanent Molars of Schoolchildren: 36-month Clinical Trial." Journal of Dental Research 84, no. 8 (2005): 721–24. http://dx.doi.org/10.1177/154405910508400807.

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We hypothesized that the six-monthly application of silver diamine fluoride (SDF) can arrest the development of caries in the deciduous dentition of six-year-old schoolchildren and prevent caries in their first permanent molars. A prospective controlled clinical trial was conducted on the efficacy of a 38% SDF solution for caries reduction. Four hundred and twenty-five six-year-old children were divided into two groups: One group received SDF solution in primary canines and molars and first permanent molars every 6 mos for 36 mos. The second group served as controls. The 36-month follow-up was
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