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Articles de revues sur le sujet « Cats as laboratory animals »

Auteur : Grafiati

Publié le 4 juin 2021

Mis à jour le 24 février 2023

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1

Lobova, D., V. Kleinova, J. Konvalinova, P. Cerna, and D. Molinkova. "Laboratory diagnostics of selected feline respiratory pathogens and their prevalence in the Czech Republic." Veterinární Medicína 64, No. 1 (January 23, 2019): 25–32. http://dx.doi.org/10.17221/93/2017-vetmed.

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Respiratory problems in cats have a multifactorial character. Therapy without the detection of pathogen is often ineffective. Our study was therefore focused on the detection of important feline respiratory bacterial pathogens such as Mycoplasma felis, Chlamydia felis and Bordetella bronchiseptica and viral pathogens such as Felid alphaherpesvirus-1 and feline calicivirus. The goal of this study was to map the occurrence of these pathogens in cat populations in the Czech Republic with the aim of introducing rapid and highly sensitive methods into routine diagnostics and to provide consulting s

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de Rivera, Christina, Jacqui Ley, Bill Milgram, and Gary Landsberg. "Development of a laboratory model to assess fear and anxiety in cats." Journal of Feline Medicine and Surgery 19, no. 6 (April 18, 2016): 586–93. http://dx.doi.org/10.1177/1098612x16643121.

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Objectives The objectives of this study were: (1) to develop a laboratory-based model to assess fear and anxiety in cats using the feline open-field test (OFT) and the feline human interaction test (HIT); and (2) to validate the model using diazepam, a known anxiolytic. Methods Laboratory-housed cats (n = 41) were first classified as fearful, mildly fearful or non-fearful by a technician familiar with the cats and also by veterinary behaviorists (GL, JL), by assessing the cats’ behavior in their home rooms. In experiment 1, each cat’s behavior was assessed in an OFT and an HIT. In experiment 2

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Fischer, Amy, Valerie AW Benka, Joyce R. Briggs, Joanne Maki, Kevin N. Morris, Kayla A. Myers, Linda Rhodes, George Robert Weedon, and Julie K. Levy. "Hybrid model intermediate between a laboratory and field study: A humane paradigm shift in feline research." Journal of Feline Medicine and Surgery 20, no. 9 (July 19, 2018): 803–10. http://dx.doi.org/10.1177/1098612x18791872.

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Objectives: Non-surgical contraceptives are under development to provide accessible, affordable and humane alternatives for the management of free-roaming cat populations. The objective of this project was to develop a research approach for promising non-surgical contraceptives using outbred cats in a simulated free-roaming setting, meeting high standards for both animal welfare and scientific rigor. Methods: A facility, specially constructed with indoor and outdoor living areas, was approved and regulated as both an animal shelter and a United States Department of Agriculture research facilit

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Ujwala Ashokrao Jadhao, Chatraguna Eknathrao Lagad, and Rajesh Kundlikrao Ingole. "Laboratory animal handling techniques, basic facilities and care: A review." World Journal of Biology Pharmacy and Health Sciences 12, no. 3 (December 30, 2022): 170–82. http://dx.doi.org/10.30574/wjbphs.2022.12.3.0239.

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Animals have been utilized in pharmaceutical scientific research and development for more than 300 years. Pharmaceutical items are a must in order to treat illnesses caused by viruses, bacteria, or homeostatic imbalance, among other causes. Pharmaceuticals must be thoroughly characterized via in vitro, in vivo, and clinical trial investigations in order to be used in humans. It is essential to quantify organism's in vivo using animals whose physiology and genetics are most similar to those of humans. Common animals used for laboratory experimental research are Cats, Rats, Dogs, Mice, Guinea pi

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Ruthrauff, Cassandra M., Julie Smith, and Leigh Glerum. "Primary Bacterial Septic Peritonitis in Cats: 13 Cases." Journal of the American Animal Hospital Association 45, no. 6 (November 1, 2009): 268–76. http://dx.doi.org/10.5326/0450268.

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The purpose of this paper is to describe the signalment, clinical signs, laboratory results, culture results, and response to treatment for primary septic peritonitis in cats. This is a retrospective study of 12 client-owned animals. Medical records were reviewed for clinical findings, laboratory results, microbial culture results, radiographic findings, diagnosis, treatment, and outcome. The overall mortality rate for this group of cats was 31%, consistent with previous reports of septic peritonitis in cats. All cats that were both bradycardic and hypothermic on presentation did not survive.

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Cossaboom, Caitlin M., Alexandra M. Medley, Jessica R. Spengler, Esther A. Kukielka, Grace W. Goryoka, Tiffany Baird, Swity Bhavsar, et al. "Low SARS-CoV-2 Seroprevalence and No Active Infections among Dogs and Cats in Animal Shelters with Laboratory-Confirmed COVID-19 Human Cases among Employees." Biology 10, no. 9 (September 11, 2021): 898. http://dx.doi.org/10.3390/biology10090898.

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Human-to-animal and animal-to-animal transmission of SARS-CoV-2 has been documented; however, investigations into SARS-CoV-2 transmission in congregate animal settings are lacking. We investigated four animal shelters in the United States that had identified animals with exposure to shelter employees with laboratory-confirmed COVID-19. Of the 96 cats and dogs with specimens collected, only one dog had detectable SARS-CoV-2 neutralizing antibodies; no animal specimens had detectable viral RNA. These data indicate a low probability of human-to-animal transmission events in cats and dogs in shelt

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Calvet, Guilherme Amaral, Sandro Antonio Pereira, Maria Ogrzewalska, Alex Pauvolid-Corrêa, Paola Cristina Resende, Wagner de Souza Tassinari, Anielle de Pina Costa, et al. "Investigation of SARS-CoV-2 infection in dogs and cats of humans diagnosed with COVID-19 in Rio de Janeiro, Brazil." PLOS ONE 16, no. 4 (April 28, 2021): e0250853. http://dx.doi.org/10.1371/journal.pone.0250853.

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Background Infection by SARS-CoV-2 in domestic animals has been related to close contact with humans diagnosed with COVID-19. Objectives: To assess the exposure, infection, and persistence by SARS-CoV-2 of dogs and cats living in the same households of humans that tested positive for SARS-CoV-2, and to investigate clinical and laboratory alterations associated with animal infection. Methods Animals living with COVID-19 patients were longitudinally followed and had nasopharyngeal/oropharyngeal and rectal swabs collected and tested for SARS-CoV-2. Additionally, blood samples were collected for l

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Grotheer, Maike, Johannes Hirschberger, Katrin Hartmann, Noemi Castelletti, and Bianka Schulz. "Comparison of signalment, clinical, laboratory and radiographic parameters in cats with feline asthma and chronic bronchitis." Journal of Feline Medicine and Surgery 22, no. 7 (September 4, 2019): 649–55. http://dx.doi.org/10.1177/1098612x19872428.

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Objectives Feline asthma (FA) and feline chronic bronchitis (CB) are common respiratory conditions in cats, frequently referred to as ‘feline lower airway disease’. However, the aetiologies of both inflammatory airway diseases are probably different. Little is known about the differences in signalment, clinical signs, laboratory abnormalities and radiographic features between cats with these two airway diseases. The aim of the study was to investigate whether certain parameters can help in differentiating between both diseases, as distinguished by airway cytology. Methods Seventy-three cats wi

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Carlstead, Kathy, Janine L. Brown, and William Strawn. "Behavioral and physiological correlates of stress in laboratory cats." Applied Animal Behaviour Science 38, no. 2 (November 1993): 143–58. http://dx.doi.org/10.1016/0168-1591(93)90062-t.

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Platto, Sara, Agathe Serres, and Ai Jingyi. "Chinese College Students’ Attitudes towards Animal Welfare." Animals 12, no. 2 (January 10, 2022): 156. http://dx.doi.org/10.3390/ani12020156.

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Understanding the attitude of stakeholders towards animals is critical for the development and improvement of animal welfare in a country. College students from veterinary, animal, and life sciences majors represent future key stakeholders that will interact with professionals from animal industries. Therefore, it is critical to understand these college students’ attitudes towards animals and their knowledge about animal welfare. The present survey aimed to investigate Chinese college students’ concerns towards different animal classes (i.e., pets, farm, laboratory, and wild animals) through t

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Araújo, Diana, Carla Lima, João R. Mesquita, Irina Amorim, and Cristina Ochôa. "Characterization of Suspected Crimes against Companion Animals in Portugal." Animals 11, no. 9 (September 20, 2021): 2744. http://dx.doi.org/10.3390/ani11092744.

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Animal crimes are a widespread phenomenon with serious implications for animal welfare, individual well-being and for society in general. These crimes are universal and represent a major problem in human/animal interaction. In Portugal, current law 69/2014 criminalizes the mistreatment and abandonment of companion animals. This study characterizes forensic cases received at the Laboratory of Pathology of the National Institute of Agrarian and Veterinary Investigation (Vairão) since the enforcement of the aforementioned legislation. A retrospective study was carried out based on the consult of

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Meanger, J. D., and R. B. Marshall. "Campylobacter jejuni infection within a laboratory animal production unit." Laboratory Animals 23, no. 2 (April 1, 1989): 126–32. http://dx.doi.org/10.1258/002367789780863637.

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A conventional laboratory animal production unit in which rats, mice, guineapigs and rabbits were bred in one building and cats maintained in a separate, but adjacent area was examined for the presence of intestinal thermophilic Campylobacter spp. Campylobacter jejuni was recovered from 18·84% of 552 animals. The infection rate was highest amongst the cats (51·7%), with rats being the second most commonly infected (23·2%), whereas only 7·7% of guineapigs and a single rabbit (1%) were positive. Campylobacter-like organisms were cultured from 10% of the mice, but these bacteria failed to grow on

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Park, Eun-sil, Osamu Fujita, Masanobu Kimura, Akitoyo Hotta, Koichi Imaoka, Masayuki Shimojima, Masayuki Saijo, Ken Maeda, and Shigeru Morikawa. "Diagnostic system for the detection of severe fever with thrombocytopenia syndrome virus RNA from suspected infected animals." PLOS ONE 16, no. 1 (January 28, 2021): e0238671. http://dx.doi.org/10.1371/journal.pone.0238671.

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Background Severe fever with thrombocytopenia syndrome virus (SFTSV) causes severe hemorrhagic fever in humans and cats. Clinical symptoms of SFTS-infected cats resemble those of SFTS patients, whereas SFTS-contracted cats have high levels of viral RNA loads in the serum and body fluids. Due to the risk of direct infection from SFTS-infected cats to human, it is important to diagnose SFTS-suspected animals. In this study, a reverse transcription polymerase chain reaction (RT-PCR) was newly developed to diagnose SFTS-suspected animals without non-specific reactions. Methodology/principle findin

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Lien, Yu-Hsin, Hui-Pi Huang, and Pen-Heng Chang. "Iatrogenic Hyperadrenocorticism in 12 Cats." Journal of the American Animal Hospital Association 42, no. 6 (November 1, 2006): 414–23. http://dx.doi.org/10.5326/0420414.

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Iatrogenic hyperadrenocorticism is an extremely rare condition in cats. Twelve cats with a medical history of progressive skin lesions and long-term treatment with corticosteroids were retrospectively studied. Noncutaneous signs in the cats were variable and included anorexia, lethargy, polydipsia, polyuria, and atrophy of the thigh muscles. Laboratory abnormalities included leukocytosis, elevated alanine aminotransferase levels, and hyperglycemia. Transient diabetes mellitus was a secondary complication in four cats, and transient hypothyroidism was suspected in four cats. The mean time for r

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Klinck, Mary P., Beatriz P. Monteiro, Bertrand Lussier, Martin Guillot, Maxim Moreau, Colombe Otis, Paulo VM Steagall, et al. "Refinement of the Montreal Instrument for Cat Arthritis Testing, for Use by Veterinarians: detection of naturally occurring osteoarthritis in laboratory cats." Journal of Feline Medicine and Surgery 20, no. 8 (September 18, 2017): 728–40. http://dx.doi.org/10.1177/1098612x17730172.

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Objectives Feline osteoarthritis causes pain and disability. Detection and measurement is challenging, relying heavily on owner report. This study describes refinement of the Montreal Instrument for Cat Arthritis Testing, for Use by Veterinarians. Methods A video analysis of osteoarthritic (n = 6) and non-osteoarthritic (n = 4) cats facilitated expansion of scale items. Three successive therapeutic trials (using gabapentin, tramadol and oral transmucosal meloxicam spray) in laboratory cats with and without natural osteoarthritis (n = 12–20) permitted construct validation (assessments of diseas

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Tochieva, O. N., and M. V. Arisov. "Therapeutic efcacy of preparations in the form of a solution for external use based on imidacloprid, pyriproxyfen and moxidectin at nematodosis of dogs and cats." Russian Journal of Parasitology 16, no. 2 (June 14, 2022): 243–51. http://dx.doi.org/10.31016/1998-8435-2022-16-2-243-251.

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The purpose of the research is to study the therapeutic efcacy of drugs in the form of a solution for external use based on imidacloprid, pyriproxyfen and moxidectin against gastrointestinal nematodes and Diroflaria spp. microflaria in dogs and cats.Materials and methods. . The studies were carried out on the basis of VNIIP (fl. Federal State Budgetary Scientifc Institution FNTs VIEV RAS) on dogs and cats of diﬀerent sex and age, body weight spontaneously infected with parasites. The diagnosis, as well as the eﬀectiveness of the drugs, was confrmed in a complex manner based on the anamnestic a

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Klaasen, H. L. B. M., J. P. Koopman, M. E. Van Den Brink, M. H. Bakker, F. G. J. Poelma, and A. C. Beynen. "Intestinal, segmented, filamentous bacteria in a wide range of vertebrate species." Laboratory Animals 27, no. 2 (April 1, 1993): 141–50. http://dx.doi.org/10.1258/002367793780810441.

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Segmented, filamentous bacteria (SFBs) form a group of bacteria with similar morphology and are identified on the basis of their morphology only. The relationships of these organisms are unclear as the application of formal taxonomic criteria is impossible currently due to the lack of an in vitro technique to culture SFBs. The intestine of laboratory animals such as mice, rats, chickens, dogs, cats and pigs is known to harbour SFBs. To see whether this extends to other animal species, intestines from 18 vertebrate species, including man, were examined. SFBs were detected with light microscopy

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Reagan, Krystle L., Lorelei L. Clarke, Jennifer R. Hawley, Phillip Lin, and Michael R. Lappin. "Assessment of the ability of Aedes species mosquitoes to transmit feline Mycoplasma haemofelis and ‘Candidatus Mycoplasma haemominutum’." Journal of Feline Medicine and Surgery 19, no. 8 (July 14, 2016): 798–802. http://dx.doi.org/10.1177/1098612x16658317.

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Objectives The objective of this study was to evaluate wild-caught mosquitoes for evidence of hemotropic Mycoplasma species DNA and to determine whether the feline hemoplasmas, Mycoplasma haemofelis (Mhf) and ‘ Candidatus Mycoplasma haemominutum’ (Mhm), can be transmitted by Aedes aegypti mosquitoes in a laboratory setting. Methods Wild-caught mosquito pools (50 mosquitoes per pool, 84 pools) utilized in routine public health department disease surveillance programs were tested for hemotropic Mycoplasma species DNA using PCR with primers designed to amplify all known hemoplasmas. Additionally,

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Gorinsky, V. I., V. V. Salautin, N. A. Pudovkin, S. D. Klyukin, and S. E. Salautina. "A comprehensive approach to the diagnosis of breast neoplasms in domestic unproductive animals." International Journal of Veterinary Medicine, no. 2 (July 23, 2022): 74–84. http://dx.doi.org/10.52419/issn2072-2419.2022.2.74.

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The spread of oncological diseases is currently one of the main problems in both humanitarian and veterinary medicine. Despite the high achievements of domestic and foreign scientists of modern veterinary medicine in the field of diagnosis, treatment and prevention of oncological processes, the number of cancer-affected animals is quite large and continues to grow steadily. Therefore, improving the complex of diagnostic studies for neoplasms among dogs and cats is one of the priority areas of veterinary medicine. The research was conducted on the basis of the veterinary clinic of the Center fo

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Puls, Christopher, Aaron Johnson, Karrie Young, Jonathan Hare, Kelly Rosenkrans, Lisa Young, and Karen Moriello. "Efficacy of itraconazole oral solution using an alternating-week pulse therapy regimen for treatment of cats with experimental Microsporum canis infection." Journal of Feline Medicine and Surgery 20, no. 10 (October 13, 2017): 869–74. http://dx.doi.org/10.1177/1098612x17735967.

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Objectives The objective of this study was to evaluate itraconazole 10 mg/ml oral solution for the treatment of Microsporum canis infection using an alternating-week pulse therapy regimen in a controlled laboratory setting. Methods Eighty cats with experimentally induced infections were randomly assigned to treatment (itraconazole vs control [sterile water]), administered 5 mg/kg PO q24h for 1 week on alternate weeks for 5 weeks, followed by a 4 week follow-up period. Topical therapeutic treatment was not administered. Cats were individually housed in stainless steel cages that were cleaned an

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Francuski, Jelena, Nenad Andric, Vojislav Ilic, Milan Jovanovic, Mirjana Lazarevic-Macanovic, Vanja Krstic, and Milica Kovacevic-Filipovic. "Retrospective analysis of clinical pathological findings in obstruction of lower urinary pathways in cats." Veterinarski glasnik 67, no. 1-2 (2013): 117–28. http://dx.doi.org/10.2298/vetgl1302117f.

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Diseases of the lower urinary pathways with urethral obstruction are frequent urological conditions demanding urgent treatment that lead to the occurrence of post renal azotemia due to difficult or disabled urine elimination. The aim of these investigations was to establish the most frequent causes for the occurrence of obstructions of the lower urinary pathways in cats, the most frequent clinical signs, as well as the changes in the hematological and biochemical blood and urine parameters. The obtained results indicate that the most frequent cause of urethral obstruction in cats is the presen

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Caylor, KB, and MK Cassimatis. "Metronidazole neurotoxicosis in two cats." Journal of the American Animal Hospital Association 37, no. 3 (May 1, 2001): 258–62. http://dx.doi.org/10.5326/15473317-37-3-258.

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Two cats were presented for neurological dysfunction from suspected metronidazole toxicity. One cat was receiving 111 mg/kg body weight per day of metronidazole for 9 weeks. After 9 weeks, the dose was increased to 222 mg/kg body weight per day, and 2 days later the cat began to experience progressive neurological signs that culminated in generalized seizures. The second cat was receiving metronidazole at a total dose of 58 mg/kg body weight per day for 6 months. This cat experienced acute onset of ataxia and alteration in mentation. Laboratory evaluations in both cases were without significan

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Munhoz, Alexandre Dias, Izabela Garcia Pinto Coelho Simões, Ana Paula Fernandes Calazans, Ludimila Santos Macedo, Rebeca Dálety Santos Cruz, Luciana Carvalho Lacerda, Roueda Abou Said, and Marcos Rogério André. "Hemotropic mycoplasmas in naturally infected cats in Northeastern Brazil." Revista Brasileira de Parasitologia Veterinária 27, no. 4 (November 14, 2018): 446–54. http://dx.doi.org/10.1590/s1984-296120180074.

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Abstract This study aimed to determine the prevalence, factors associated, laboratory findings (with and without coinfection by retroviruses) among naturally infected cats by hemoplasmas in northeastern Brazil. For convenience, 200 domesticated and healthy cats were selected. Blood samples were taken to perform complete blood counts, serum biochemical, immunochromatography tests and nPCR for FIV and FeLV, and PCR for hemoplasma recognition. An interview was conducted to determine the factors associated with hemoplasmas. A total of 71/200 (35.5%) cats were positive for at least one hemoplasma s

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SG, Ciornei. "SARS-CoV-2 in Animals-Evolution and Associated Risks." Open Access Journal of Veterinary Science & Research 5, no. 1 (2020): 1–7. http://dx.doi.org/10.23880/oajvsr-16000196.

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It is emphasized that the medical staff is subject to a maximum risk, and so it is. Due to permanent contact with potentially contaminated patients, carriers may be infected or carry the virus. In this context, it is highlighted that veterinarians may have a high risk of infection. In the world literature, and international epizootic forums, it reports and publishes information on the presence of COVID19 in animals. Some animals have been confirmed with this virus, generally pets that come from families where there have been several carrier members. Pets that tested positive showed clinical si

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Caney, Sarah. "Weight Loss in the Elderly Cat: Appetite is Fine, and Everything Looks Normal …" Journal of Feline Medicine and Surgery 11, no. 9 (September 2009): 738–46. http://dx.doi.org/10.1016/j.jfms.2009.07.008.

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Practical relevance Improvements in general health care and nutrition have meant that more cats are living to an advanced age. Weight loss is one of the most common presenting signs in the older cat. Many causes of weight loss in older cats are at least amenable to supportive care and some are curable. Clinical challenges Weight loss is a non-specific change and, while often a sensitive indicator of ill health, does not readily point to the diagnosis. Careful history taking and physical examination may indicate a specific cause but, as discussed in this article, further tests are generally req

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Ponomarenko, G. V., V. L. Kovalenko, O. V. Ponomarenko, R. V. Severyn, A. M. Gontar, V. I. Shostak, A. M. Strashnenko, О. О. Humeniuk, and О. О. Andriienko. "Monitoring of Dermatophytosis incidence in domestic dogs and cats in Kharkiv, Ukraine." Journal for Veterinary Medicine, Biotechnology and Biosafety 5, no. 1 (March 25, 2019): 17–19. http://dx.doi.org/10.36016/jvmbbs-2019-5-1-4.

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The spread of dermatophytosis among animals and humans in the localities of Ukraine in particular in the city of Kharkiv is due to the presence of range of the most susceptible animals. This information mainly concerns dogs and cats that can be affected by dermatophytosis and may be a reservoir of dermatophyte fungus. Particularly important is that domestic dogs and cats represent a significant epidemiological threat to the population. The purpose of the research was to monitor the morbidity of dermatophytosis in domestic dogs and cats in Kharkiv. Diagnostic studies of dermatophytosis morbidit

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BAKER, M. G., L. D. LOPEZ, M. C. CANNON, G. W. DE LISLE, and D. M. COLLINS. "Continuing Mycobacterium bovis transmission from animals to humans in New Zealand." Epidemiology and Infection 134, no. 5 (March 29, 2006): 1068–73. http://dx.doi.org/10.1017/s0950268806005930.

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New Zealand has a large reservoir of Mycobacterium bovis infection in wild and farmed animals. This study aimed to assess the extent of human infection with this organism and the potential contribution of these animal sources. Combined epidemiological and laboratory investigation of human tuberculosis cases over the period 1995–2002 showed that M. bovis accounted for 2·7% (54/1997) of laboratory-confirmed human tuberculosis cases, a rate of 0·2/100000 population. M. bovis isolates from humans (23) were typed using restriction endonuclease analysis (REA) and compared with isolates from wild and

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Bertazzolo, W., L. Toscani, S. Calcaterra, L. Crippa, M. Caniatti, and U. Bonfanti. "Clinicopathological Findings in Five Cats with Paw Calcification." Journal of Feline Medicine and Surgery 5, no. 1 (February 2003): 11–17. http://dx.doi.org/10.1053/jfms.2002.0195.

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This retrospective study describes the clinicopathological findings in five cats with soft tissue mineralisation of interdigital spaces and footpads. Paw disease was the reason for veterinary consultation in three out of five cats. All cats had laboratory findings suggestive of renal failure and high solubility product [calcium x phosphorus]. In all cases, cytological examination of paw lesions was suggestive of calcinosis. The results of our study agree with two previous case reports of paw calcification in the cat, suggesting a metastatic pathogenesis and a correlation between paw mineralisa

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Sousa-Filho, Reginaldo P., Diana CS Nunes-Pinheiro, Keytyanne O. Sampaio, Ellen CB da Silva, Grazielle ASA Cavalcanti, and Marina Gabriela MC Mori da Cunha. "Clinical outcomes of 28 cats 12–24 months after urethrostomy." Journal of Feline Medicine and Surgery 22, no. 10 (December 6, 2019): 890–97. http://dx.doi.org/10.1177/1098612x19888808.

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Objectives The aim of this study was to evaluate and compare the long-term clinical outcomes and quality of life of cats having undergone perineal urethrostomy (PU) or prepubic urethrostomy (PPU). Methods This clinical study followed 28 cats (PU, n = 22; PPU, n = 6) that underwent a urethrostomy, with a minimum of 1 year postoperative follow-up. Medical records, pet owner surveys and urologic laboratory tests were used for assessment. Urologic laboratory tests included serum symmetric dimethylarginine (SDMA), serum creatinine, urinalysis, urine specific gravity (USG), urine protein:creatinine

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Zenchenkova, A. P. "STUDY OF THE EFFECTIVENESS OF RALTEGRAVIR (ISENTRESS, MSD, USA) IN REGENERATIVE ANEMIA ASSOCIATED WITH VIRAL LEUKEMIA IN CATS." Scientific Life 16, no. 4 (2021): 509–18. http://dx.doi.org/10.35679/1991-9476-2021-16-4-509-518.

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The leukemia virus is widespread in the population of domestic cats and, despite the study of this disease, there is no effective therapy aimed at complete eradication of the virus from the body of an infected animal. One of the most life-threatening conditions associated with the frequent death and euthanasia of infected animals is anemia. This retrospective study is aimed at evaluating the effectiveness of the drug “Isentress” (MSD, USA) with the active substance Raltegravir against regenerative anemia associated with feline viral leukemia. In the group of animals receiving this drug, a decr

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Jones, Emily, John Alawneh, Mary Thompson, and Rachel Allavena. "Association between case signalment and disease diagnosis in urinary bladder disease in Australian cats and dogs." Journal of Veterinary Diagnostic Investigation 33, no. 3 (April 2, 2021): 498–505. http://dx.doi.org/10.1177/10406387211004008.

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Urinary bladder diseases are common in dogs and cats; however, there is little published work on urinary bladder disease in Australian pets. We identified pathology records of Australian dogs and cats with urinary bladder tissue submitted to the University of Queensland Veterinary Laboratory Service during 1994–2016 ( n = 320). We described the proportion of bladder diseases in dogs and cats, and applied the less-commonly used logistic regression procedure to quantify associations between signalment variables and disease diagnosis that were evident using descriptive statistics alone. After pre

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Morozenko, Dmytro, Yevheniia Vashchyk, Andriy Zakhariev, Nataliia Seliukova, Dmytro Berezhnyi, and Kateryna Gliebova. "Diabetes mellitus in domestic cats: clinical cases from veterinary practice." ScienceRise: Biological Science, no. 4(33) (December 30, 2022): 31–34. http://dx.doi.org/10.15587/2519-8025.2022.266536.

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The aim: to analyze clinical cases of diabetes mellitus in cats and establish the effectiveness of clinical and laboratory research and treatment of animals with the help of insulin therapy. Materials and methods. The material for the study were domestic cats admitted to the veterinary medicine clinic "Doctor Vet" (Lviv). Results. Clinical case 1. Cat Bonya, age 10 years, body weight 4 kg. symptoms: polyuria/polydipsia and weight loss. Examination: cachexia, weakness, pale mucous membranes, unsteady gait. Blood glucose - 20.4 mmol/l, urine analysis - pH=6.0, glucose ++++, no ketone

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Gustafson, Tanya L., Armando Villamil, Bonnie E. Taylor, and Andrea Flory. "A Retrospective Study of Feline Gastric Lymphoma in 16 Chemotherapy-Treated Cats." Journal of the American Animal Hospital Association 50, no. 1 (January 1, 2014): 46–52. http://dx.doi.org/10.5326/jaaha-ms-5989.

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The purposes of this study were to describe cases of feline gastric lymphoma with regards to signalment, clinical presentation, laboratory and ancillary study findings, response to therapy, and outcomes and to identify prognostic variables. Sixteen cats with stage I and II gastric lymphoma treated with chemotherapy were included in this study. Seventy-five percent of cats experienced remission. Overall, first remission duration was 108 days. Response to treatment was prognostic as in other types of feline lymphoma. Cats with a complete remission (CR) had longer survival times compared with cat

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Sohn, Joanne, Theresa Gruber, and Gaylord M. Brown. "Retrospective Study on the Effects of Long-Term Use of Methylprednisolone Acetate on the Blood Work of 25 Cats." Journal of the American Animal Hospital Association 55, no. 1 (January 1, 2019): 23–28. http://dx.doi.org/10.5326/jaaha-ms-6783.

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ABSTRACT Twenty-five cats at a private animal sanctuary received multiple nonimmunosuppressive doses of parenteral methylprednisolone acetate for at least 3 yr. Complete blood count, chemistry, and T4 results from these cats were examined to look for statistically significant changes. Results found significant changes in triglycerides, amylase, and monocytes. However, these changes remained within the reference interval. All other values showed no significant changes. These results suggest that after 3 yr of chronic parenteral administration of nonimmunosuppressive doses of methylprednisolone

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Aulakh, Harmeet K., Karanvir S. Aulakh, and Gregory C. Troy. "Feline Histoplasmosis: A Retrospective Study of 22 Cases (1986–2009)." Journal of the American Animal Hospital Association 48, no. 3 (May 1, 2012): 182–87. http://dx.doi.org/10.5326/jaaha-ms-5758.

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Twenty-two cases of feline histoplasmosis seen at the Virginia-Maryland Regional College of Veterinary Medicine Teaching Hospital between 1986 and 2009 were reviewed. The median age of affected cats was 9 yr (mean, 8.8 yr). Female domestic shorthairs were more commonly affected. The clinical presentation of most cases was nonspecific. The most common presenting complaints included weakness, lymphadenopathy, weight loss, and anorexia. Less frequent clinical signs included vomiting, diarrhea, blindness, and lameness. Less than half of the cats had clinical evidence of pulmonary disease on admiss

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Viebrock, Kayla A., and Jeff Dennis. "Hypoglycemic episodes in cats with diabetes mellitus: 30 cases (2013–2015)." Journal of Feline Medicine and Surgery 20, no. 6 (August 17, 2017): 563–70. http://dx.doi.org/10.1177/1098612x17722853.

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Objectives The purpose of this study was to review the characteristics of diabetic cats presenting to a specialty and emergency center for signs attributed to hypoglycemia and to identify the factors that may have contributed to the hypoglycemic episode, the patient’s clinical signs and laboratory findings, and the response of hypoglycemic cats to therapy. Methods Twenty-eight cats were presented a total of 30 times for symptomatic hypoglycemia. Data were collected from cat owners at the time of presentation and from subsequent patient records. Results The majority of cats presented for neurol

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Brunt, Scott, Heather Solomon, Kathleen Brown, and April Davis. "Feline and Canine Rabies in New York State, USA." Viruses 13, no. 3 (March 10, 2021): 450. http://dx.doi.org/10.3390/v13030450.

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In New York State, domestic animals are no longer considered rabies vector species, but given their ubiquity with humans, rabies cases in dogs and cats often result in multiple individuals requiring post-exposure prophylaxis. For over a decade, the New York State rabies laboratory has variant-typed these domestic animals to aid in epidemiological investigations, determine exposures, and generate demographic data. We produced a data set that outlined vaccination status, ownership, and rabies results. Our data demonstrate that a large percentage of felines submitted for rabies testing were not v

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Łagowski, Dominik, Sebastian Gnat, Mariusz Dyląg, and Aneta Nowakiewicz. "Laboratory Diagnosis and In Vitro Antifungal Susceptibility of Trichophyton quinckeanum from Human Zoonoses and Cats." Antibiotics 11, no. 6 (May 30, 2022): 739. http://dx.doi.org/10.3390/antibiotics11060739.

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The “One Health” concept increasingly demonstrates the global spread of pathogenic (also eukaryotic) microorganisms and their zoonotic potential. Dermatophytes can cause superficial mycoses in humans and animals. Furthermore, the number of transmissions from asymptomatic carriers to humans has been on the rise over the last few years. This study was focused on the detailed characterisation of clinical isolates of Trichophyton quinckeanum with epidemiological analyses and characterisation of their in vitro antifungal susceptibility patterns. The isolated dermatophytes were identified with a com

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Fried, Arno, Kenneth Shapiro, Futoshi Takei, and Ira Kohn. "A laboratory model of shunt-dependent hydrocephalus." Journal of Neurosurgery 66, no. 5 (May 1987): 734–40. http://dx.doi.org/10.3171/jns.1987.66.5.0734.

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✓ This study was designed to determine whether implanting shunts in hydrocephalic cats produced the same biomechanical changes as have previously been found in children with shunts. Neuraxis volume-buffering capacity (pressure-volume index: PVI) and the resistance to the absorption of cerebrospinal fluid (CSF) were determined before and 3 weeks after placing shunts in 16 hydrocephalic cats. Intracranial pressure (ICP) was monitored for at least 6 hours after the shunts were occluded. The brains were perfused in vivo and removed to assess the size of the ventricles. The mean PVI of the hydrocep

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Evangelista, Gabriela CL, Lorraine RSM Dornelas, Cristiane CV Cintra, Fabrício L. Valente, Evandro S. Favarato, Leandro A. da Fonseca, and Emily CC Reis. "Evaluating feline lower urinary tract disease: Doppler ultrasound of the kidneys." Journal of Feline Medicine and Surgery 25, no. 1 (January 2023): 1098612X2211454. http://dx.doi.org/10.1177/1098612x221145477.

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Objectives Ultrasonography is used in the evaluation of urinary disorders, and the resistivity index (RI) and pulsatility index (PI) have been successfully used to detect early hemodynamic changes in the course of kidney diseases in humans and dogs. The aim of this study was to investigate RI and PI in cats with feline lower urinary tract disease (FLUTD). Methods Twenty-nine client-owned cats were selected and divided into a control group (CG; n = 10), a group of animals with obstructive FLUTD (OG; n = 11) and non-obstructive FLUTD (nOG; n = 8). Clinical, laboratory and ultrasound evaluations

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Sarbu, Luminita, Barbara E. Kitchell, and Philip J. Bergman. "Safety of administering the canine melanoma DNA vaccine (Oncept) to cats with malignant melanoma – a retrospective study." Journal of Feline Medicine and Surgery 19, no. 2 (July 10, 2016): 224–30. http://dx.doi.org/10.1177/1098612x15623319.

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Objectives A xenogeneic human tyrosinase DNA vaccine was developed for treatment of dogs with oral malignant melanoma (Oncept; Merial). No studies have evaluated the safety or efficacy of this vaccine in cats. The purpose of this study was to evaluate the safety of the canine melanoma vaccine in cats diagnosed with melanoma. Methods Medical records were reviewed from cats diagnosed with malignant melanoma and treated with the canine melanoma DNA vaccine (Oncept). Data regarding signalment, melanoma location, treatments received, vaccine adverse effects and cause of death were collected. Result

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Tochieva and Arisov. "STUDY OF THE EFFICACY OF COMBINED IMIDACLOPRID-, PYRIPROXYFEN- AND MOXIDECTIN-BASED DRUGS AGAINST ECTOPARASITOSIS IN DOGS AND CATS." THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL, no. 23 (April 18, 2022): 459–64. http://dx.doi.org/10.31016/978-5-6046256-9-9.2022.23.459-464.

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We studied therapeutic and prophylactic efficacy of new drugs against ectoparasitosis in dogs and cats. New veterinary drugs for dogs and cats were developed with the combined active substances (Imidacloprid, Pyriproxyfen and Moxidectin) in the form of a spot-on solution for external application at the premises of the VNIIP – FSC VIEV. The difference between the drugs is the different content of Moxidectin – the Moxidectin content is 2.5 times higher in the drug for dogs than the drug for cats. The studies were performed on dogs and cats of different sex, age, body weight and breed spontaneous

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Schaefer, Sandra, Hans S. Kooistra, Barbara Riond, Jan S. Suchodolski, Jörg M. Steiner, Marrit Prins, Eric Zini, and Claudia E. Reusch. "Evaluation of insulin-like growth factor-1, total thyroxine, feline pancreas-specific lipase and urinary corticoid-to-creatinine ratio in cats with diabetes mellitus in Switzerland and the Netherlands." Journal of Feline Medicine and Surgery 19, no. 8 (August 30, 2016): 888–96. http://dx.doi.org/10.1177/1098612x16664390.

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Objectives The aim of the study was to evaluate circulating insulin-like growth factor-1 (IGF-1), feline pancreas-specific lipase (fPLI) and total thyroxine (TT4) concentrations and urinary corticoid-to-creatinine ratio (UCCR) as indicators for the prevalence of acromegaly, pancreatitis, hyperthyroidism and hypercortisolism in cats with diabetes mellitus. Methods Blood and urine samples were collected from diabetic cats treated in primary care clinics in Switzerland and the Netherlands. Standardised questionnaires and physical examination forms provided clinical information from owners and vet

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Arbona, Nichole, Christine D. Butkiewicz, Minta Keyes, and Lisa F. Shubitz. "Clinical features of cats diagnosed with coccidioidomycosis in Arizona, 2004–2018." Journal of Feline Medicine and Surgery 22, no. 2 (February 20, 2019): 129–37. http://dx.doi.org/10.1177/1098612x19829910.

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Objectives The goal of this study was to describe the clinical presentation, diagnosis and treatment of coccidioidomycosis in cats residing in a region endemic for Coccidioides species. Methods A retrospective review of records was performed at both primary and tertiary care veterinary practices in Tucson and Phoenix, Arizona, USA. Data collected included signalment, clinical signs, physical examination findings, diagnostic test results, treatment and outcome. Results Fifty-one feline cases were identified from six veterinary hospitals. Cats presented with clinical signs and laboratory abnorma

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Mazur, M., N. Mazur та I. Polupan. "Видова характеристика епізоотії сказу в Україні за 2011–2016 рр." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 19, № 73 (7 січня 2017): 159–62. http://dx.doi.org/10.15421/nvlvet7333.

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The article presents analysis of dynamics of the animal rabies incidence and characteristics of rabies epizootic situation for the animal species in Ukraine from 2011–2016. We analyzed the laboratory research expertise, reports of regional departments of Veterinary Medicine and the State Veterinary and Phytosanitary Service of Ukraine (now State Service of Ukraine on issues of food safety and consumer protection) for the period from 2011 to 2016, and the information that is presented in the Rabies Bulletin Europe. During this period in Ukraine registered 8807 cases of rabies among 17 animal sp

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Haskins, M. E., E. J. Otis, J. E. Hayden, P. F. Jezyk, and L. Stramm. "Hepatic Storage of Glycosaminoglycans in Feline and Canine Models of Mucopolysaccharidoses I, VI, and VII." Veterinary Pathology 29, no. 2 (March 1992): 112–19. http://dx.doi.org/10.1177/030098589202900203.

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Livers from normal cats and dogs, cats with mucopolysaccharidoses (MPS) I and VI, and dogs with MPS VII were analyzed biochemically and morphometrically to determine the lysosomal storage of glycosaminoglycans (GAG) in these animal models of human genetic disease. Analyses were performed on liver samples from seven normal cats ranging in age from 13 weeks to 15 months; six MPS I-affected cats ranging in age from 10 weeks to 26 months; four MPS VI-affected cats ranging in age from 9 months to 32 months; four normal dogs ranging in age from 1 month to 47 months; and three MPS VII-affected dogs,

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Wilmes, Dunja, Ursula Mayer, Peter Wohlsein, Michael Suntz, Jasmin Gerkrath, Christoph Schulze, Ina Holst, Wolf von Bomhard, and Volker Rickerts. "Animal Histoplasmosis in Europe: Review of the Literature and Molecular Typing of the Etiological Agents." Journal of Fungi 8, no. 8 (August 9, 2022): 833. http://dx.doi.org/10.3390/jof8080833.

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Histoplasmosis has been previously diagnosed in animals from Europe. The aim of this study is to review the literature on these reports, to analyze cases diagnosed at our laboratory (2000–2022) and to improve molecular typing of Histoplasma capsulatum directly from tissue to study the molecular epidemiology of Histoplasma capsulatum causing animal infections in Europe. Including 15 cases studied in our laboratory, we identified 39 cases of animal histoplasmosis between 1968 and 2022. They were diagnosed mostly in superficial tissue biopsies from cats and badgers from Central Europe. Using phyl

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Summers, Stacie C., Rebecca Ruch-Gallie, Jennifer R. Hawley, and Michael R. Lappin. "Effect of modified live or inactivated feline herpesvirus-1 parenteral vaccines on clinical and laboratory findings following viral challenge." Journal of Feline Medicine and Surgery 19, no. 8 (July 18, 2016): 824–30. http://dx.doi.org/10.1177/1098612x16659333.

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Objectives The objective was to investigate the effect of one dose of an inactivated feline herpesvirus-1 (FHV-1), feline calicivirus (FCV) and panleukopenia virus (FPV) vaccine (FVRCP) or one dose of a modified live (ML) FVRCP vaccine on clinical signs and shedding of FHV-1 in specific pathogen-free kittens after challenge with FHV-1 7 days after vaccination. Methods Twenty-four FHV-1 seronegative 5-month-old kittens were randomized into three groups of eight kittens. Group 1 kittens were maintained as unvaccinated controls, group 2 kittens were administered one dose of the inactivated FVRCP

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Peterson, Mark E., Mark Rishniw, Graham E. Bilbrough, and Kate B. Cote. "Comparison of in-clinic point-of-care and reference laboratory total thyroxine immunoassays for diagnosis and post-treatment monitoring of hyperthyroid cats." Journal of Feline Medicine and Surgery 20, no. 4 (May 12, 2017): 319–24. http://dx.doi.org/10.1177/1098612x17708918.

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Objectives The Catalyst One Chemistry Analyzer (IDEXX Laboratories) is a point-of-care instrument that can measure total thyroxine (TT4) by immunoassay. The aims of this study were to evaluate the analytic performance of the Catalyst TT4 assay in feline sera and to examine agreement of the Catalyst TT4 results with those measured by immunoassay at a veterinary reference laboratory. Methods Assay precision, reproducibility and linearity were evaluated for the Catalyst TT4 assay. For method comparison, TT4 concentrations in serum samples from 157 cats (127 hyperthyroid, 30 radioiodine-treated ca

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Robbins, Michael T., Martha G. Cline, Joseph W. Bartges, Erin Felty, Korinn E. Saker, Richard Bastian, and Angela L. Witzel. "Quantified water intake in laboratory cats from still, free-falling and circulating water bowls, and its effects on selected urinary parameters." Journal of Feline Medicine and Surgery 21, no. 8 (October 10, 2018): 682–90. http://dx.doi.org/10.1177/1098612x18803753.

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ObjectivesThe study objectives were to determine if the method of water presentation (still [S], circulating [C] or free-falling [FF] bowl systems) influences daily water consumption in cats in a controlled environment, and whether differences in water intake affect urine relative super saturation (RSS) for calcium oxalate and struvite, urine specific gravity (USG), urine osmolality (Uosmol) and urine volume.MethodsSixteen healthy laboratory cats fed a dry diet were individually housed with urine collection systems. Each cat underwent a randomized 2 week crossover period with all bowl systems,

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