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1

BURBA, ILARIA. "Analysis of differentiation, plasticity and biological activity of human endothelian progenitor cells (HEPC): insights from epigenetic assessment and clinical applications." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2010. http://hdl.handle.net/10281/20193.

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Despite advances in the management of CVDs, they continue to be a major medical problem in western countries. Current pharmacologic and interventional strategies fail to regenerate dead myocardium and are often insufficient to avoid ventricular remodelling. In this context cell therapy is emerging, and in particular stem cell therapy, due to the great potential of these cells. In this framework we attempted to provide a contribution in three main issues relative to EPC therapy: 1) We established standard operating procedures (SOPs) to purify human CB CD133+ cells using CliniMACS and applied t
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Kelur, Ashok. "Model checking of multicore software using CBMC." Thesis, Uppsala universitet, Institutionen för informationsteknologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-182169.

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Computers have been key subsystems in various complex systems. As computers are adapted into various fields, hardware and software are increasing in size and complexity. It is evident that parallel computing is the way to solve large scale complex information technology problems. Engineers designing hardware and software are required to verify the system for correctness. As system's size and complexity increases, it is difficult to perform manual system verification. Model checking converts a hardware or software solution into temporal logic and uses solvers to assert on properties of solution
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Joshi, Kaushal V. "Novel Neuroprotectants for Sarin plus CBDP induced convulsions." Wright State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=wright1253321185.

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Mora, Carlos A. "Comparison of computation methods for CBM production performance." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-1958.

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Claeson, Holmgren Mathilda, and Tilda Göransson. "Cirkulär ekonomi på mikronivå : En fallstudie om hur ett mikroföretag imodebranchen kan agera för att sluta kretsloppet." Thesis, Högskolan i Borås, Akademin för textil, teknik och ekonomi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-14768.

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I Sverige är 93% av alla existerande företag i mikrostorlek. Trots det finns det väldigt lite forskning på hur de ska gå tillväga för att implementera en cirkulär affärsmodell. Syftet med studien är att undersöka vilka förutsättningarna ett modeföretag i mikrostorlek kan ha för att implementera cirkulära affärsmodeller.   Dagens ekonomiska system bygger på linjära affärsmodeller. Det betyder att människor köper, använder och sedan slänger produkter som fortfarande har ett potentiellt ekonomiskt värde. Cirkulära affärsmodeller utgör ett alternativ till dagens ekonomiska system. Det bygger på at
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Corral, Rego Lía. "Validación del Cuestionario de Sesgos Cognitivos para la Psicosis (CBQp): Relación con sintomatología, insight y neurocognición." Doctoral thesis, Universitat Rovira i Virgili, 2019. http://hdl.handle.net/10803/670511.

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Introducció: Els biaixos cognitius són clau en la formació i manteniment dels deliris en la psicosi. El Cognitive Biases Questionnaire for Psychosis (CBQp) avalua cinc tipus de biaixos cognitius en la psicosi. L'objectiu d'aquest treball es validar la versió espanyola del CBQp, i estudiar la relació d'aquests biaixos cognitius amb la simptomatologia psicòtica, l’insight i la neurocognició. Material i mètode: La versió espanyola autoritzada del CBQp va ser obtinguda segons el procés de traducir-retrotraducció. La mostra va estar composta per 171 subjectes amb diagnòstics de psicosis. Una anàlis
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Rosén, Joel, and Magnus Olsson. "Tillståndsbaserat underhåll till sjöss : Vad föranleder den begränsade användningen av tillståndsbaserat underhåll (CBM) till sjöss?" Thesis, Linnéuniversitetet, Sjöfartshögskolan (SJÖ), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-25461.

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Today, maintenance is a big part of the daily life on board ships. It is also one of the bigger expenses a shipping company has and without any loss of quality tries to run as economically advantageous as possible. In the hunt for economical savings the shore-based industry has subsequently applied the use of condition based maintenance, CBM, were a component is maintained according to its actual state. This leads to a reduction of maintenance costs since no parts are unnecessarily replaced. However, within the maritime sector a periodical maintenance is still the most commonly used maintenanc
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Delvecchio, Manuela. "Mécanisme de régulation de l'acétyltransférase p300/CBP." Phd thesis, Université de Grenoble, 2011. http://tel.archives-ouvertes.fr/tel-00631344.

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Le p300/CBP acétyltransférase est un co-activateur transcriptionnel très important qui est impliqué dans la régulation d'un grand nombre de processus biologiques, comme la transcription d'ADN, le développement et l'immunité innée. Jusqu'à présent, le rôle de p300/CBP dans la régulation de l'expression des gènes a été largement étudiée, mais les mécanismes qui régulent son activité enzymatique sont encore peu connus. Des études ont montré que le dysfonctionnement de p300/CBP est associé à plusieurs formes de cancer et de maladies neurodégénératives. Dés lors, chaque progrès concernant les mécan
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Klein, Fabrice. "Etudes structurales des interactions CBP-récepteurs nucléaires." Université Louis Pasteur (Strasbourg) (1971-2008), 2003. http://www.theses.fr/2003STR13241.

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Les récepteurs nucléaires (NRs) forment une famille de facteurs de transcription dont l'activité est contrôlée par la fixation de ligands. La liaison à un ligand agoniste permet le recrutement de coactivateurs transcriptionnels, comme les p300/CREB‑Binding­Protein (p300/CBP) et les p160/Steroid‑Receptor­‑Coactivator (p160/SRC). Ces protéines possèdent plusieurs motifs LxxLL (L = Leucine ; X = n'importe quel acide aminé), responsables de l'interaction aux NRs. Nous avons caractérisé le domaine de CBP interagissant aux LBDs et co‑cristallisé un complexe de l'extrémité Nterminale de CBP (Nter‑CBP
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Xue, Lili. "Numerical well testing of coalbed methane (CBM) reservoir." Thesis, Heriot-Watt University, 2012. http://hdl.handle.net/10399/2655.

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Numerical experiments and field applications proved that there exist percolation non-linearity and fluid multi-variability in low permeability CBM reservoirs. The percolation of fluid needs to overcome threshold pressure gradient, and klinkenberg effects will restrict the gas permeability. In addition, production enhancement and ultimate recovery improvement have given multi-branch horizontal wells the advantage over the vertical wells in many CBM marginal reservoirs. Moreover, Enhance Coalbed Methane (ECBM) recovery through injection of gases has been publicly proven, and can increase gas res
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Xu, Lan. "Integration of signal-induced transcriptional activation by CBP /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1998. http://wwwlib.umi.com/cr/ucsd/fullcit?p9911841.

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Kang, Hyun-Seo. "Structural foundation for transcriptional regulation by Ets1 and CBP." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/28866.

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Using cell-based assays and biophysical measurements, we have defined the mechanism by which Ras/MAP kinase signaling enhances Ets1 regulated gene expression via phosphorylation-enhanced recruitment of the transcriptional co-activator CBP. As confirmed by ³¹P/¹³C-NMR experiments, the MAP kinase ERK2 phosphorylates Thr38 and Ser41 within the unstructured region of Ets1, immediately N- terminal to the PNT domain. The NMR-derived structure of residues 29-138 of Ets1 revealed that the PNT domain is composed of a core four-helix bundle (H2-H5), also known as the SAM fold, appended with two addition
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Francis, Yitshak Itsik. "The role of CBP and p300 in Alzheimer's Disease." Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/1443955/.

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Studies of the mechanisms underlying memory formation have defined central roles for CRE-dependent gene expression, which is mediated by the transcription factor CREB and the coactivator CBP. CBP creates a bridge between CREB and the basal transcriptional machinery and acetylates histones, which induces chromosomal changes and results in loss of chromosomal repression. This allows successful transcription of the underlying genes needed for synthesis of proteins underlying memory formation. CBP has been linked to neurodegenerative diseases and cerebral CBP levels were shown to reduce in mice la
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Gusterson, Rosalind Jane. "The role of CBP and p300 in cardiac hypertrophy." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399576.

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Sajtar, Eric T. "Toolbox to evaluate treatment technologies for PRB CBM water." Laramie, Wyo. : University of Wyoming, 2008. http://proquest.umi.com/pqdweb?did=1594485851&sid=1&Fmt=2&clientId=18949&RQT=309&VName=PQD.

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Ramaswamy, Sunil. "Selection of best drilling, completion and stimulation method for coalbed methane reservoirs." Texas A&M University, 2007. http://hdl.handle.net/1969.1/85835.

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Over the past three decades, coalbed methane (CBM) has moved from a mining hazard and novel unconventional resource to an important fossil fuel that accounts for approximately 10% of the U.S. natural gas production and reserves. The expansion of this industry required development of different drilling, completion and stimulation practices for CBM in specific North American basins, owing to the complex combinations of geologic settings and reservoir parameters encountered. These challenges led to many technology advances and to development of CBM drilling, completion and stimulation technology
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Sudwell, Mark Ian. "Chronic back pain : a narrative analysis." Thesis, University of Exeter, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367457.

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Alvarez, David 1971. "The involvement of CBP/14-3-3 in DNA replication /." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=82819.

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Initiation of DNA replication is a cellular process whose regulation is not well understood yet. It certainly depends on cis-acting elements, or origins of DNA replication sequences, and trans-acting factors, or initiator proteins. Here, we have characterized the Cruciform Binding Protein (CBP) as an origin binding protein and its role in initiation of DNA replication.<br>CBP was previously shown to contain the β, ɣ, ε, and ζ isoforms of the 14-3-3 family, which is composed of seven mammalian isoforms (β, ɣ, ε, η, σ, τ, and ζ) that can form homo- and heterodimers, and plays a variety o
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Songkumarn, Pattavipha. "Identification and Characterization of In-planta Expressed Secreted Effector Proteins from Magnaporthe oryzae." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1357158502.

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Feldmann, Gregory Michael. "Early numeracy: technical adequacy of select kindergarten and first grade screening measures." Diss., University of Iowa, 2012. https://ir.uiowa.edu/etd/2869.

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Because of a greater need to focus on early achievement in mathematics and increased global competition in this area, emphasis is increasingly being placed upon screening and monitoring of math development in early elementary to ensure progress for all students. Although protocols for early literacy assessment exist, research of psychometrically sound and instructionally useful early numeracy assessment methods is still developing. Thus, the current study was undertaken to further develop and examine early numeracy measure
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Sebastianelli, Massimo. "World Class Manufacturing : approccio ad un sistema di manutenzione predittiva (CBM)." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2016.

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L’oggetto di analisi del presente lavoro di tesi è il modello di Operational Excellence noto come World Class Manufacturing in particolare l’approccio allo step 6 del pilastro Professional Maintenance, dove si richiede l’implementazione di un sistema di manutenzione PREDITTIVA, la cosiddetta CBM (Conditional Based Maintenance) . Il modello a cui si fa riferimento fu teorizzato dal professore giapponese H. Yamashina verso la metà degli anni 2000 e giunse in Italia attorno al 2005, quando Fiat Group (oggi FCA) lo adottò come approccio standard alla gestione della produzione. Questo tipo di ana
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Gensterblum, Yves [Verfasser]. "CBM and CO2-ECBM related sorption processes in coal / Yves Gensterblum." Aachen : Hochschulbibliothek der Rheinisch-Westfälischen Technischen Hochschule Aachen, 2013. http://d-nb.info/1047230712/34.

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Gao, Wenxue [Verfasser], and Reinhard [Akademischer Betreuer] Männer. "Active Buffer Development in CBM Experiment / Wenxue Gao ; Betreuer: Reinhard Männer." Heidelberg : Universitätsbibliothek Heidelberg, 2012. http://d-nb.info/1179784413/34.

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Soremekun, Mishael. "Readmission in psychosis and in CBTp : associations with patient education level and belief flexibility status." Thesis, Royal Holloway, University of London, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604562.

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Background and objectives Previous studies have shown that Cognitive Behavioural Therapy for psychosis (CBTp) does not reduce readmission rates. This could be due to particular patient characteristics. This study sought to assess whether patients' education level and belief flexibility status were associated with readmission following CBTp treatment. The association between other psycho-social factors and readmission was also explored. Method Using the South London and Maudsely NHS Trust case register, 3025 adult patients with an F20-F29 ICD-1O diagnosis, discharged from inpatient care to the
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Ramírez, Sandra. "Role du coactivateur cbp dans l activite du sre de c-fos." Paris 12, 1999. http://www.theses.fr/1999PA120092.

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La proteine cbp, connue pour etre un coactivateur de plusieurs facteurs de transcription dependants du signal est un integrateur des differents voies de signalisation et elle est aussi impliquee dans la regulation de la transcription du proto-oncogene c-fos. Nous avons partie de la hypothese que cbp cooperer avec srf pour la l'activation transcriptionnelle en reponse au serum l'element sre. Dans une premiere etude faite dans la lignee cellulaire f9 nous avons montre que cbp stimule de facon dose dependante l'activite du gene rapporteur luciferase sous le controle de l'element sre du promoteur
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Menezes, Sean Christopher. "Examining the effect of CBP on the E2A-PBX1 and HOXB4 interaction." Thesis, Kingston, Ont. : [s.n.], 2008. http://hdl.handle.net/1974/1534.

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Kavoosi, Mojgan. "The CBM9 fusion tag : a new technology for inexpensive production and affinity purification of recombinant proteins." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/31363.

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Downstream processing of proteins and other biological products has long been dominated by packed-bed chromatography (Rankin 2003). Despite the generally high cost of the technique, chromatography remains widely used because it offers extraordinarily high resolution under conditions that do not denature or alter the chemistry of the product, an imperative for therapeutic proteins since purity and activity are strict requirements. However, the inability of patients and governments to meet the rising costs of healthcare, particularly the cost of recombinant protein therapeutics, and the sharp in
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Smyth, Amy Marie. "An investigation into the initial validity of the Canterbury behaviour screening protocol (CBSP): a pilot study." Thesis, University of Canterbury. Health Sciences, 2006. http://hdl.handle.net/10092/1406.

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This study was a pilot investigation of the initial validity of a newly developed behaviour-screening instrument for early intervention service providers. Group Special Education, Early Intervention (GSE/EI) (2005) adapted the Canterbury Behaviour Screening Protocol (CBSP) from a widely used behaviour-screening instrument the Early Screening Project. The CBSP consisted of 49 items in 2 checklists. GSE/EI identified 10 early childhood centres with a total roll of 712 to participate in the study. Staff were asked to categorise children's problem behaviours as either withdrawn/isolated or
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De, Santis Paola. "Contagious bovine pleuropneumonia (CBPP) : studies on the disease and causative agent (Mycoplasma mycoides subsp. mycoides SC)." Thesis, King's College London (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425092.

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GRIGORIADIS, ILIAS. "Evaluation of a Contactless Excitation and Response System for Condition Based Maintenance." Thesis, KTH, Industriell produktion, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-192809.

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New environmental regulations as well as the increasing industrial competitiveness have set new more demanding rules on the manufacturing industry. In order to abide by those rules not only from the legal point of view but also to be able survive, manufacturing has to be more sustainable from many aspects, especially the economical one. One way to achieve the previous target is an unfortunately often oversighted aspect of the industry sector, the maintenance strategy. Condition based maintenance, CBM, can be used successfully in the industry and accurate estimation of spindle life time can lea
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Gouveia, Ayden. "The Atypical Protein Kinase C - Creb Binding Protein Pathway Regulates Post-Stroke Neurovascular Remodeling and Functional Recovery." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/35674.

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Ischemic stroke related brain damage causes loss of multiple cell types, including neural and vascular cells. The extent of post-stroke neurogenesis and angiogenesis predicts the level of functional regeneration/recovery after stroke. In this regard, my thesis was focused on defining the molecular process that modulates post-stroke functional recovery by co-ordinating post-stroke neurovascular remodeling. Since stroke-related brain damage releases enriched local microenvironmental cues, I examined the role of a signaling-induced epigenetic pathway, an atypical protein kinase C (aPKC)-mediated
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Sköld, Michael, and Almbladh Jacob. "Kartläggning och analys av scanias tillsynsprogram : Ett verktyg för förbättring." Thesis, Uppsala universitet, Industriell teknik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-202001.

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Scania intends to introduce a new maintenance program for their rolling fleet. Withthis new program Scania hopes to increase their competiveness and add furthercustomer value. This thesis report is a mapping of the current maintenance program,along with its problematic features. Furthermore the report intends to describe thenew program, Condition Based Maintenance (CBM) and the problems that Scaniamust deal with before they can implement it.The report compiles basic information on how a mapping should be performed.Further on it will describe some of the theories of LEAN and leadership. Which a
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Fan, Chung-Hau. "An examination of the equivalence of the first grade DIBELS oral reading fluency probes." Diss., University of Iowa, 2011. https://ir.uiowa.edu/etd/2698.

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Given the change in federal legislation allowing the consideration of a Response-To-Intervention (RTI) approach to making eligibility decisions for specific learning disabilities (IDEIA, 2004), it is crucial to establish sufficient evidence for using curriculum-based measurements (CBM) or CBM-like measures (e.g., Dynamic Indicators of Basic Early Literacy Skills; DIBELS) for monitoring students' responses to interventions as part of the identification process for Specific Learning Disabilities. One critical component in an effective RTI model is the availability of parallel measures suited for
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Hancock, Kyle Max. "The Utility of Mathematics Curriculum-Based Measurement to Predict Student Risk Status on Standardized Academic Achievement Measures." DigitalCommons@USU, 2009. https://digitalcommons.usu.edu/etd/435.

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The predictive utility of mathematics curriculum-based measurement (MCBM) to identify students who are at risk for failure on important educational measures is an emerging area of study in need of further investigation. The present study sought to identify which of four MCBM probes could be accurately used to determine students' risk status on selected subtests of three important educational measures commonly used to make educational placement decisions (WIAT-II, WJ-ACH-III, and KM 3) in grades 2 (n = 49), 4 (n = 48), and 6 (n = 47). The study also sought to determine which type of student p
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Hassan, Ali Mohamed. "Couplage diagnostic pronostic pour la maintenance prévisionnelle des systèmes photovoltaïques." Thesis, Amiens, 2018. http://www.theses.fr/2018AMIE0016.

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Dans ce travail, nous avons développé une méthode de couplage d'un processus de diagnostic à base de modèle avec un processus de prognostic issu de l'expérience au moyen d'une architecture OSA-CBM (Open System Architecture for Condition Based Maintenance). Pour cela, le modèle 2M7P de la cellule photovoltaïque est optimisé par la mise en œuvre d'une méthode métaheuristique d'extraction des sept paramètres, FodPSO. Cette optimisation permet de mieux reproduire la performance de la cellule surtout en conditions réelles de fonctionnement. L'approche du diagnostic est traitée par la quantification
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Xanidis, Nikos. "Exploring the implementation of Cognitive Behavioural Therapy for psychosis (CBTp) using the Normalisation Process Theory (NPT) framework." Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/30812/.

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Objective: Evidence suggests that only a minority of service users experiencing psychosis have access to Cognitive Behavioural Therapy for psychosis (CBTp). Normalisation Process Theory (NPT) is a theoretical framework which focuses on processes by which interventions are implemented and normalised in clinical practice. This study explored the views and experiences of mental health professionals regarding the implementation of CBTp. Barriers and facilitators to implementation were explored using the NPT framework. Design: A qualitative methodology was adopted involving semi-structured focus gr
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Hauser, Fabien. "Expression augmentée de la protéine de signalisation Cbp/PAG dans les lymphomes malins /." Genève : [s.n.], 2004. http://www.unige.ch/cyberdocuments/theses2004/HauserF/these.pdf.

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Zhang, Zuwen. "Functional analysis of the mouse CBP gene in the adult central nervous system." Thesis, Open University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390810.

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Wenk, Sandra. "Epigenetic regulation of nuclear receptor mediated transcription : Arginine methylation of the coactivator CBP." Université Louis Pasteur (Strasbourg) (1971-2008), 2007. http://www.theses.fr/2007STR13135.

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Akande, Oluwatoyin E. "INVESTIGATING THE MECHANISM OF THE COMPARTMENTALIZED CBP (CREB-BINDING PROTEIN) UBIQUITIN LIGASE ACTIVITIES." VCU Scholars Compass, 2016. http://scholarscompass.vcu.edu/etd/4438.

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CBP (CREB Binding Protein) is global transcriptional co-activator and histone acetyltransferase. CBP is involved in the modulation of the transcription of many genes via histone acetylation at the promoter regions of the target genes. Also, non-histone proteins and transcription factors can be acetylated by CBP to promote their transcriptional activation. In addition to its transcription co-activator role, CBP is involved in many other pathological and physiological cellular processes such as cell growth and differentiation, cell transformation and development, response to stress, cell cycle r
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Wong, King Hei. "Solving combinatorial based chemical engineering problems via parallel evolutionary approaches /." View abstract or full-text, 2009. http://library.ust.hk/cgi/db/thesis.pl?CBME%202010%20WONGK.

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Xu, Jingjing. "Magnetic particle based sensing platform for oligonucleotide and PCR amplicon detection /." View abstract or full-text, 2010. http://library.ust.hk/cgi/db/thesis.pl?CBME%202010%20XU.

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Zhang, Haifeng. "Reduction of methanol crossover in direct methanol fuel cells by an integrated anode structure and composite electrolyte membrane /." View abstract or full-text, 2010. http://library.ust.hk/cgi/db/thesis.pl?CBME%202010%20ZHANG.

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Xu, Ruoyu. "Downstream processing of microalgal biodiesel production /." View abstract or full-text, 2010. http://library.ust.hk/cgi/db/thesis.pl?CBME%202010%20XUR.

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Zhou, Ping. "Preparation, characterization and in vivo evaluation of polyether polyol-platinate conjugate /." View abstract or full-text, 2010. http://library.ust.hk/cgi/db/thesis.pl?CBME%202010%20ZHOU.

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Lau, Richard Yiu-Ting. "Study of surfaces of semi-crystalline polymers by static time-of-flight secondary ion mass spectrometry /." View abstract or full-text, 2010. http://library.ust.hk/cgi/db/thesis.pl?CBME%202010%20LAU.

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47

Chan, Sen Ki. "Development and characterization of functionalized magnetic nanoparticle-based method for species-specific genomic DNA extraction /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?CBME%202008%20CHAN.

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48

Chan, Yik Chung. "Solubility measurement apparatus for rapid determination of solid-liquid equilibrium behavior /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?CBME%202008%20CHANY.

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49

Wang, Huan. "Synthesis, purification and applications of carbon nanomaterials and their polymer nanocomposites /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?CBME%202008%20WANG.

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50

Lu, Junde. "Model migration based on process similarity /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?CBME%202008%20LU.

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