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Littérature scientifique sur le sujet « Cellule neuronali »

Auteur : Grafiati
Publié le 9 mars 2023
Mis à jour le 19 juillet 2025

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Articles de revues sur le sujet "Cellule neuronali"

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Ricquebourg, Rebekah, and Nikolaos Konstantinides. "Un mécanisme temporel pour la génération de la diversité neuronale." médecine/sciences 40, no. 3 (2024): 251–57. http://dx.doi.org/10.1051/medsci/2024012.

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L’un des plus grands défis des neurosciences est de comprendre comment une structure complexe, telle que le cerveau, se construit. L’encodage spatial et temporel des progéniteurs neuronaux permet la génération de l’essentiel de la diversité neuronale. Cette revue se concentre sur l’expression séquentielle de facteurs de transcription temporels, qui modifie la capacité des cellules souches à générer différents types de neurones et qui est conservée chez plusieurs espèces animales. Des publications récentes ont permis, en particulier, une compréhension fine de ce processus au cours du développem
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Benaïssa, Ibtissem. "Analogie du transport neuronal au transport électronique en nanotechnologie." Journal of Renewable Energies 12, no. 1 (2023): 9–28. http://dx.doi.org/10.54966/jreen.v12i1.115.

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Le système nerveux est formé de deux types de cellules: les cellules gliales et les neurones. Les astrocytes, comme la plupart des cellules gliales, ont longtemps été considérés essentiellement pour leur rôle de support et d’entretien du tissu nerveux. Mais, de plus en plus d’évidences plaident en faveur d’une implication beaucoup plus importante des astrocytes dans la communication nerveuse. Les astrocytes sont couplés les uns aux autres par des ‘gap-jonctions’ à travers lesquels peuvent circuler divers métabolites. C’est par ces jonctions que les astrocytes évacuent vers les capillaires, le
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VILETTE, D., and H. LAUDE. "Pathogenèse des Encéphalopathies Spongiformes Transmissibles : apports des modèles cellulaires." INRAE Productions Animales 17, HS (2004): 23–30. http://dx.doi.org/10.20870/productions-animales.2004.17.hs.3621.

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Malgré des efforts répétés et soutenus lors des 30 dernières années, le nombre de modèles permettant l’étude en culture cellulaire de la multiplication des prions était, jusqu’à récemment, extrêmement restreint. Il s’agissait, pour l’essentiel, de quelques lignées cellulaires, ne permettant la multiplication que de rares souches expérimentales de prions. Pour tenter de pallier ces insuffisances, un projet a été initié en vue d’établir des modèles capables notamment de permettre la multiplication et l’étude de souches naturelles de prions. Quatre nouveaux modèles cellulaires ont été obtenus. S’
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Ronzitti, Emiliano, Dimitrii Tanese, Alexis Picot, Benoît C. Forget, Valentina Emiliani, and Eirini Papagiakoumou. "Holographie numérique pour la photostimulation de circuits neuronaux." Photoniques, no. 92 (July 2018): 34–37. http://dx.doi.org/10.1051/photon/20189234.

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Le développement de techniques originales de manipulation de la lumière ont permis de grandes avancées dans le domaine de l’optogénétique. Elles permettent d’étudier et de stimuler la communication au sein des circuits neuronaux et du cerveau avec une précision spatiale et temporelle correspondant à l’activation d’une cellule unique au sein d’un circuit.
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Behar-Cohen, Francine, Emmanuelle Gelizé, Laurent Jonet, and Patricia Lassiaz. "Anatomie de la rétine." médecine/sciences 36, no. 6-7 (2020): 594–99. http://dx.doi.org/10.1051/medsci/2020094.

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La neurorétine est une unité fonctionnelle du système nerveux central assurant la conversion d’un signal lumineux en un influx nerveux. D’origine neuroectodermique, dérivée du diencéphale, la neurorétine est un tissu stratifié, composé de six types de cellules neuronales (deux types de photorécepteurs : les cônes et les bâtonnets ; les cellules horizontales, bipolaires, amacrines et ganglionnaires) et de trois types de cellules gliales (les cellules gliales de Müller, les astrocytes et les cellules microgliales). La neurorétine repose sur l’épithélium pigmentaire rétinien, l’ensemble constitua
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Lledo, Pierre-Marie. "Cellules souches neuronales." Morphologie 99, no. 327 (2015): 154. http://dx.doi.org/10.1016/j.morpho.2015.09.012.

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Dumbacher, Michael, Dooren Tom Van, Katrien Princen та ін. "Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease". Molecular Neurodegeneration 13, № 1 (2018): 50. https://doi.org/10.1186/s13024-018-0283-3.

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<strong>Background: </strong>Neuronal Ca<sup>2+</sup> dyshomeostasis and hyperactivity play a central role in Alzheimer's disease pathology and progression. Amyloid-beta together with non-genetic risk-factors of Alzheimer's disease contributes to increased Ca<sup>2+</sup> influx and aberrant neuronal activity, which accelerates neurodegeneration in a feed-forward fashion. As such, identifying new targets and drugs to modulate excessive Ca<sup>2+</sup> signalling and neuronal hyperactivity, without overly suppressing them, has promising therapeutic potential.<strong>Methods: </strong>Here we sh
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Rakotobe, Malalaniaina, and Chiara Zurzolo. "Les tunneling nanotubes." médecine/sciences 40, no. 11 (2024): 829–36. https://doi.org/10.1051/medsci/2024152.

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Les tunneling nanotubes (TNT) sont des protrusions membranaires ouvertes permettant la communication directe entre cellules distantes. Des recherches récentes ont révélé leur importance biologique, notamment dans le système nerveux où leurs rôles pourraient être cruciaux. Observés dans le cerveau en développement, les TNT sont impliqués dans les maladies neurodégénératives, les cancers du cerveau et dans d’autres types de maladies, soulignant leur rôle physiopathologique. Leur découverte pourrait conduire à reconsidérer le cerveau comme un réseau neuronal physiquement connecté, complémentant a
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Baratas Díaz, Luis Alfredo. "Significación histórica de La rétine des Vertébrés de Santiago Ramón y Cajal: Síntesis de su primera etapa investigadora." Asclepio 46, no. 1 (1994): 243. http://dx.doi.org/10.3989/asclepio.1994.v46.1.482.

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La retina fue uno de los objetos de estudio preferentes en la primera etapa de la obra científica de Ramón y Cajal. Como culminación de sus trabajos previos, Cajal publicó en 1893 en La Cellule un artículo titulado «La rétine des Vertébrés», en el que se aprecian las influencias más significativas que pesaron sobre su obra. Este trabajo sobre la retina ilustra perfectamente su capacidad para el estudio sistemático de los tipos celulares de los centros nerviosos, su descripción morfológica y los contactos intercelulares, así como para formular interpretaciones fisiológicas coherentes con las ob
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Corner, M. A. "Neuronal and cellular oscillators." Journal of the Neurological Sciences 92, no. 2-3 (1989): 349. http://dx.doi.org/10.1016/0022-510x(89)90150-0.

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Thèses sur le sujet "Cellule neuronali"

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CAPORALI, SIMONA. "Cellule staminali neuronali e microglia: cross - talk in modello in vitro di neuroinfiammazione." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2009. http://hdl.handle.net/10281/7547.

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Inhibition of microglia-mediated neuroinflammation is an important terapeuthic target in order to avoid cognitive and motor impairment in brain ischemia . Reportedly, neural stem cell (NSC) brain grafts have neuroprotective effecs 1. It has been proposed that these positive effects are not caused only by NSC proliferation and generation of new neurons, but also by a modulation of the brain lesion environment 2. Our primary aim was to ascertain whether NSC were capable of modifying microglial activation in vitro. We used ATP as inflammatory stimuli, since it is massively released from damaged n
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Fabbri, Roberta. "Dispositivi biomedici avanzati per il controllo selettivo della funzionalità di cellule cerebrali non neuronali." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amslaurea.unibo.it/19539/.

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Gli studi degli ultimi quarant’anni hanno evidenziato che gli astrociti, cellule non neuronali del Sistema Nervoso Centrale, pur essendo definite cellule non eccitabili, sono attivamente coinvolti nel mantenimento dell'omeostasi cerebrale e nel controllo della trasmissione sinaptica. I meccanismi alla base della funzionalità degli astrociti, ed in particolare i segnali mediati da variazioni della concentrazione di calcio intracellulare stanno emergendo come potenziale bersaglio per lo sviluppo di applicazioni tecnologiche in neuroscienze. Fra i materiali a base di carbonio, il grafene ed i suo
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MARACCHIONI, ALESSIA. "Il danno mitocondriale modula lo splicing alternativo in cellule neuronali: implicazioni per la neurodegenerazione." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2009. http://hdl.handle.net/2108/851.

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Il danno mitocondriale è associato a molte malattie neurodegenerative, quali: Parkinson, Alzheimer e Sclerosi Laterale Amiotrofica. Queste malattie sono associate anche a cambiamenti di isoforme tramite splicing alternativo di alcuni geni. In questo lavoro dimostriamo che il danneggiamento mitocondriale modula lo splicing alternativo in maniera generale. Cellule di neuroblastoma umano sono state incubate con l’agente chimico paraquat (una neurotossina che danneggia i mitocondri e crea stress ossidativo) e analizzate mediante RT-PCR per il pattern di splicing di 13 geni. Tutti gli mRNAs soggett
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Padovan, Marco. "Interfacce nanostrutturate, dispositivi ottici ed elettronici per lo studio della fisiologia di cellule cerebrali non neuronali." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/16293/.

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Gli astrociti, cellule non eccitabili del cervello, dapprima considerate solo cellule di supporto all’attività neuronale, hanno un ruolo centrale nella fisiologia cerebrale mantenendo l’omeostasi di ioni, acqua e neurotrasmettitori, e modulando anche l’attività neuronale, attraverso il rilascio di neurotrasmettitori. La disfunzione degli astrociti può concorrere alla patogenesi di neuropatologie acute e croniche come Ischemia o Malattia di Alzheimer. Gli astrociti svolgono li loro funzioni tramite canali ionici, trasportatori e canali per l’acqua e comunicando attraverso segnali di calcio intr
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Torricella, Giulia. "Bioelettronica organica: Nuovi approcci tecnologici per la stimolazione e la rilevazione della comunicazione di cellule neuronali." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/8520/.

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Il campo della Bioelettronica si è sviluppato a partire dal 18 secolo con l’ esperimento di Luigi Galvani che, applicando uno stimolo elettrico ai muscoli di una rana dissezionata, ne osservò il movimento. Da questo esperimento si è aperta la strada che ha portato ad oggi ad un grande sviluppo tecnologico nella realizzazione di dispositivi elettronici che permettono di offrire un miglioramento generale delle condizioni di vita. Come spesso accade con le tecnologie emergenti, i materiali sono la maggiore limitazione nello sviluppo di nuove applicazioni. Questo è certamente il caso della Bioele
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Nizzardo, M. "UTILIZZO E CONFRONTO TRA CELLULE STAMINALI NEURONALI DI DIVERSA ORIGINE: EFFICACIA TERAPEUTICA IN UN MODELLO MURINO DI ATROFIA MUSCOLARE SPINALE." Doctoral thesis, Università degli Studi di Milano, 2009. http://hdl.handle.net/2434/157862.

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Spinal muscular atrophy (SMA), characterized by selective loss of lower motor neurons, is an incurable genetic neurodegenerative disease.and represents one of the most common genetic causes of infant mortality. Patients with SMA exhibit muscle weakness and hypotonia. Stem cell transplantation is a potential therapeutic strategy for SMA and other motor neuronal diseases. In this study, we analized the therapeutic capacity of different stem cells sources in order to improve SMA phenotype in a SMA murine model. First of all we isolated spinal cord neural stem cells (NSCs) from mice expressing g
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MERLO, SARA. "Effetti degli estrogeni sul differenziamento e sulla neurodegenerazione in sistemi neuronali in vitro." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2004. http://hdl.handle.net/2108/208233.

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L’obiettivo del presente lavoro è stata l’identificazione di un ruolo per il recettore degli estrogeni (ER) nel neurosviluppo e nella neurodegenerazione, con particolare attenzione al coinvolgimento delle cellule gliali. E’ noto che gli estrogeni influenzano lo sviluppo, la maturazione ed il differenziamento dei neuroni nel sistema nervoso centrale, e che i suoi recettori mostrano un picco di espressione durante le fasi precoci di neurosviluppo. La zona subventricolare del cervello di topo adulto è una ricca fonte di progenitori neurali. Questi possono essere mantenuti in coltura, in un mez
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Mastromauro, Michela Pia. "La Bioelettronica Organica: approcci tecnologici per la registrazione, stimolazione e la modulazione di segnali elettrofisiologici di cellule neuronali per finalità terapeutiche nell'ambito della medicina neuro-rigenerativa." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2019.

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La Bioelettronica organica è una disciplina sviluppatosi a partire dal XVII secolo con l’esperimento di Luigi Galvani che, applicando uno stimolo elettrico ai muscoli di una rana dissezionata, ne osservò il movimento. La Bioelettronica organica è un’evoluzione della suddetta disciplina nel quale elementi di natura biologica vengono combinati con dispositivi elettronici avanzati, basati sull’utilizzo di materiali organici, con lo scopo di realizzare dispositivi in grado di interagire con la materia vivente per sviluppare nuove metodologie diagnostiche, di analisi e terapeutiche. L’accoppiamento
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Ronsisvalle, Nicole Victoria. "Effetti protettivi del 1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclo-propanecarboxylic Acid (CHF5074) su cellule neuronali sottoposte a stimoli tossici in vitro." Doctoral thesis, Università di Catania, 2012. http://hdl.handle.net/10761/1114.

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Protective effects of 1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic Acid(CHF5074) on neural cells challenged with toxic stimuli in vitro. Nicole Ronsisvalle, Renato Bernadini,Rosa Chillemi Dept of Clinical and Molecular Biomedicine, section on Pharmacology and Biochemistry, Univ of Catania Sch Med, 95125 Catania, Italy Alzheimer¡¦s disease (AD) is the most common form of dementia. The basic pathological abnormalities in AD brains are: amyloid plaques, neurofibrillary tangles and neuronal loss. Amyloid plaques are composed of £]-amyloid (A£]) peptides that are proteolyt
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BOVIO, FEDERICA. "The cadmium altered oxidative homeostasis leads to energetic metabolism rearrangement, Nrf2 activation with increased GSH production and reduced SOD1 activity in neural cells." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2021. http://hdl.handle.net/10281/309982.

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Il cadmio, elemento chimico ampiamente usato in ambito industriale, è considerato un contaminante ambientale con effetti tossici sugli organismi viventi. Il suo ingresso nel corpo umano può avvenire per inalazione o ingestione di cibi ed acqua contaminati, fumo di sigaretta o impiego professionale, con tratto respiratorio e gastrointestinale principalmente coinvolti nel suo assorbimento cellulare. Anche il cervello è un bersaglio della tossicità del cadmio, che può entrare nel sistema nervoso centrale tramite una maggiore permeabilità della barriera ematoencefalica o attraverso i nervi olfatti
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Livres sur le sujet "Cellule neuronali"

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1935-, Jacklet Jon W., ed. Neuronal and cellular oscillators. Marcel Dekker, 1989.

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M, Baudry, Thompson Richard F, and Davis Joel L. 1942-, eds. Synaptic plasticity: Molecular, cellular, and functional aspects. MIT Press, 1993.

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Ehrlich, Yigal H., ed. Molecular and Cellular Mechanisms of Neuronal Plasticity. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-4869-0.

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Nguyen, Laurent, and Simon Hippenmeyer, eds. Cellular and Molecular Control of Neuronal Migration. Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-007-7687-6.

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C, O'Neill, and Anderton B, eds. Neuronal signal transduction and Alzheimer's disease. Portland Press, 2001.

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Walkinshaw, Gail. An investigation into cellular and molecular mechanisms of neurotoxin-induced neuronal celldeath. University of Manchester, 1996.

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1958-, Maiese Kenneth, ed. Neuronal and vascular plasticity: Elucidating basic cellular mechanisms for future therapeutic discovery. Kluwer Academic Pub., 2003.

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name, No. Neuronal and vascular plasticity: Elucidating basic cellular mechanisms for future therapeutic discovery. Kluwer Academic Publishers, 2003.

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Andrew, Bulloch, ed. The Cellular basis of neuronal plasticity: Physiology, morphology, and biochemistry of molluscan neurons. Manchester University Press, 1989.

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D, Coleman Paul, Higgins Gerald A, Phelps Creighton H, and National Institute on Aging Symposium on Molecular and Cellular Mechanisms of Neuronal Plasticity in Aging and Alzheimer's Disease (1989 : Bethsda, Md.), eds. Molecular and cellular mechanisms of neuronal plasticity in normal aging and Alzheimer's disease. Elsevier, 1990.

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Chapitres de livres sur le sujet "Cellule neuronali"

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Goldman, Jennifer S., and Timothy E. Kennedy. "Neuronal Domains." In Cellular Domains. John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118015759.ch22.

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Gustafsson, L. E., C. U. Wiklund, N. P. Wiklund, and L. Stelius. "Subclassification of Neuronal Adenosine Receptors." In Purines in Cellular Signaling. Springer New York, 1990. http://dx.doi.org/10.1007/978-1-4612-3400-5_30.

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Sotelo, J. R., J. M. Verdes, A. Kun, J. C. Benech, J. R. A. Sotelo Silveira, and A. Calliari. "Regulation of Neuronal Protein Synthesis by Calcium." In Calcium and Cellular Metabolism. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4757-9555-4_11.

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Bruzzone, Matteo, Enrico Chiarello, Andrea Maset, Aram Megighian, Claudia Lodovichi, and Marco dal Maschio. "Light-Based Neuronal Circuit Probing in Living Brains at High Resolution: Constraints and Layouts for Integrating Neuronal Activity Recording and Modulation in Three Dimensions." In Neuromethods. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2764-8_3.

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AbstractUnderstanding how the brain orchestrates neuronal activity to finely produce and regulate behavior is an intriguing yet challenging task. In the last years, the progressive refinement of optical techniques and light-based molecular tools allowed to start addressing open questions in cellular and systems neuroscience with unprecedented resolution and specificity. Currently, all-optical experimental protocols for simultaneous recording of the activity of large cell populations with the concurrent modulation of the firing rate at cellular resolution represent an invaluable tool. In this scenario, it is becoming everyday more evident the importance of sampling and probing the circuit mechanisms not just in a single plane, but extending the exploration to the entire volume containing the involved circuit components. Here, we focus on the design principles and the hardware architectures of all-optical approaches allowing for studying the neuronal dynamics at cellular resolution across a volume of the brain.
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Hara, Hirokazu, and Elias Aizenman. "Oxidative Stress and Neuronal Zinc Signaling." In Zinc Signals in Cellular Functions and Disorders. Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-55114-0_4.

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Nakaishi, Hitoshi. "Functionally Distinct Oncogenes Differently Regulate Cellular Expression of Gangliosides." In Gangliosides and Modulation of Neuronal Functions. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71932-5_30.

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Timofeev, Igor, Maxime E. Bonjean, and Maksim Bazhenov. "Cellular Mechanisms of Thalamocortical Oscillations in the Sleeping Brain." In Neuronal Oscillations of Wakefulness and Sleep. Springer New York, 2020. http://dx.doi.org/10.1007/978-1-0716-0653-7_5.

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Augusti-Tocco, G., S. Biagioni, M. Plateroti, G. Scarsella, and A. L. Vignoli. "Cellular and Molecular Aspects of Neuronal Differentiation." In The Changing Visual System. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3390-0_23.

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Woodgett, James R. "Analysis of protein phosphorylation in cell lines." In Neuronal Cell Lines. Oxford University PressOxford, 1992. http://dx.doi.org/10.1093/oso/9780199633463.003.0006.

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Abstract Protein phosphorylation now is regarded as the pre-eminent mechanism of post-translational regulation. Its reversibility, rapid kinetics, and specificity of effect has resulted in its exploitation by most systems of cellular control. Hence, studies of the mechanisms by which cells transduce and respond to signals commonly involve some aspect of this covalent modification. The ability to introduce high specific activity radioisotopes into cultured cells, together with their ease of manipulation and harvest, has made cell lines the system of choice for studying the dynamic processes of protein phosphorylation. In this chapter are described basic techniques for assessing the influence and role of phosphorylation in a given process using cultured cells. Given the increasing realization of the importance and ubiquity of this form of modification, these methods should be of widespread use to researchers wishing to dissect the molecular bases of cellular controls.
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VERKHRATSKY, O. N. "NEURONAL-GLIAL NETWORKING." In ESSAYS ON NEUROPHYSIOLOGY BY PLATON KOSTYUK AND HIS STUDENTS. AKADEMPERIODYKA, 2020. https://doi.org/10.15407/biph.books.essneur.152.

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The concept of neuroglia as a connective tissue into which all elements of the central nervous system (CNS) are embedded was introduced by Rudolf Virchow (Virchow, 1856, Virchow, 1858, Kettenmann and Verkhratsky, 2008). Virchow never considered the cellular nature of glia; for him neuroglia was not more than a sort of extracellular binding element, and he often referred to it as a "Nervwenkitt" (i.e. nerve cement). Very soon, however, the cellular nature of glial cells was identified and many types of neuroglial cells were described. In the course of late 19th — early 20th century the cellular nature and morphofunctional heterogeneity of neuroglial cells were firmly established (Kцlliker, 1889, Andriezen, 1893, Lenhossek, 1893, Retzius, 1894-1916, Golgi, 1903). In the recent decades the functional relevance and versatility of neuroglia which is involved in all activities of the brain, from structural and metabolic support to information processing has started to be fully appreciated (Verkhratsky and Kettenmann, 1996, Kettenmann and Ransom, 2005, Volterra and Meldolesi, 2005, Verkhratsky, 2006b, Verkhratsky, 2006a, Verkhratsky and Toescu, 2006, Verkhratsky and Butt, 2007, Kettenmann and Verkhratsky, 2008, Verkhratsky, 2009). Furthermore, the evolutionary uniqueness of human glial cells (Oberheim et al., 2009, Verkhratsky, 2009) indicates their specific role in the formation of human intelligence.
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Actes de conférences sur le sujet "Cellule neuronali"

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Shin, Sangho, Davide Sacchetto, Yusuf Leblebici, and Sung-Mo Steve Kang. "Neuronal spike event generation by memristors." In 2012 13th International Workshop on Cellular Nanoscale Networks and their Applications (CNNA 2012). IEEE, 2012. http://dx.doi.org/10.1109/cnna.2012.6331427.

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Roukes, Michael L. "The Integrated Neurophotonics Paradigm." In CLEO: Applications and Technology. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/cleo_at.2022.ath4i.6.

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Integrated neurophotonics can surmount limitations of existing methodologies to enable fast and dense large-scale functional imaging of neuronal activity from within the brain itself. Implantable lens-less nanophotonic arrays yield cellular resolution at arbitrary brain depths.
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Wagner, Omer, Alexander K. Winkel, Eva Kreysing, and Kristian Franze. "Multimodal imaging using combined Optical Fourier Ptychographic Microscopy and Atomic Force Microscopy for biological measures." In CLEO: Applications and Technology. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/cleo_at.2022.atu5i.3.

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We present a platform that perform live imaging using Fourier Ptychographic Microscopy co-localised with Atomic Force Microscopy. This specially fit emerging research on cellular biological processes regulated by tissue mechanics, including neuronal growth and stem-cell differentiation.
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Li, Lulu, Alexander Davidovich, Jennifer Schloss, et al. "Control of Neural Lineage Differentiation in an Alginate Encapsulation Microenvironment via Cellular Aggregation." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206496.

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Cell replacement therapies, which utilize renewable stem cell sources, hold tremendous potential to treat a wide range of degenerative diseases. Although many studies have established techniques to successfully differentiate stem cells into different mature cell lineages, their practicality is limited by the lack of control during the differentiation process and low yields of differentiated cells. In order to address these issues, we have previously established a murine embryonic stem cell alginate-poly-L-lysine microencapsulation differentiation system [1]. We demonstrated that ES cell differ
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Me´ndez-Rojas, Miguel A., Claudia Cravioto Guzman, and Oscar Arias-Carrion. "Synthesis and Chemical Functionalization of Ferromagnetic Nanoparticles to Manipulate Stem Cells Using External Magnetic Fields." In ASME 2007 5th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2007. http://dx.doi.org/10.1115/icnmm2007-30188.

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The human brain is able to respond to several situations that promotes neural survivance, growth and neuronal cells regeneration. The potential of stem cells from the subventricular zone to be used for neuronal cell substitution has been widely studied. However, migration of endogen or transplanted cells is random, not efficient and with a very low survivance rate. The use of ferromagnetic nanoparticles may be of interest to guide the stem cells to the desired site using external fields. In this project, we have synthesized ferromagnetic nanoparticles (magnetite) with an average diameter of 10
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Silvestri, Ludovico, Nikita Rudinskiy, Marco Paciscopi, et al. "Brain-wide charting of neuronal activation maps with cellular resolution." In Bio-Optics: Design and Application. OSA, 2015. http://dx.doi.org/10.1364/boda.2015.brm3b.6.

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Hyttinen, Jari, Barbara Genocchi, Annika Ahtiainen, Jarno M. A. Tanskanen, Kerstin Lenk, and Michael Taynnan Barros. "Astrocytes in modulating subcellular, cellular and intercellular molecular neuronal communication." In NANOCOM '21: The Eighth Annual ACM International Conference on Nanoscale Computing and Communication. ACM, 2021. http://dx.doi.org/10.1145/3477206.3477460.

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Silvestri, Ludovico, Nikita Rudinskiy, Marco Paciscopi, et al. "Brain-wide charting of neuronal activation maps with cellular resolution." In Optics and the Brain. OSA, 2015. http://dx.doi.org/10.1364/brain.2015.brm3b.6.

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Patlis, AsiaLuna. "Cellular and molecular effects of weight stigma: The effect of cortisol on hypothalamic neurons in vitro." In 10th Annual International Weight Stigma Conference. Weight Stigma Conference, 2024. https://doi.org/10.31076/2024.p22.

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Weight stigma has been associated with changes to the stress-responsive hypothalamic-pituitary-adrenocortical (HPA) axis. Chronic activation of the HPA axis leads to elevated levels of circulating glucocorticoids such as cortisol. This poster will show a project proposal to study the cellular and molecular effects of cortisol on human arcuate-like hypothalamic neurons in vitro. The arcuate nucleus of the hypothalamus (ARC) is involved in the homeostatic regulation of body weight and feeding. The ARC is home to two important neuronal populations: proopiomelanocortin (POMC) and agouti-related ne
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Li, Lulu, Rene Schloss, Noshir Langrana, and Martin Yarmush. "Effects of Encapsulation Microenvironment on Embryonic Stem Cell Differentiation." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192587.

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Pluripotent embryonic stem cells represent a promising renewable cell source to generate a variety of differentiated cell types. Although many investigators have described techniques to effectively differentiate stem cells into different mature cell lineages, their practicality is limited by the absence of large scale processing consideration and low yields of differentiated cells. Previously we have established a murine embryonic stem cell alginate-poly-l-lysine microencapsulation differentiation system. The three-dimensional alginate microenvironment maintains cell viability, is conducive to
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Rapports d'organisations sur le sujet "Cellule neuronali"

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Cheepsunthorn, Poonlarp, and Yong Poovorawan. Identification of receptors for H5N1 virus on human nerve cells using protromics-based approaches. Chulalongkorn University, 2013. https://doi.org/10.58837/chula.res.2013.12.

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In this study, we investigated neuroinfectious capacity of H5N1 (A/Thailand/NK165/2005) isolated from plasma of infected individual during the third wave of Thailand outbreaks using human neuroblastoma SH-SY5Y cells. This was due to lack of information regarding neuroinfectivity of this variant. Results demonstrated that H5N1/NK165 induced servere CPEs in these neuronal cells. H5N1-specific hemagglutinin was found in the cytoplasm of the infected cells as early as 12 h post-infection. By 24 h post-infection, all cells in the cultures were infected. These findings coincided with time course of
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Patumraj, Suthiluk, and Sheepsumon Viboolvorakul. Protective effects of exercise training against vascular and neuronal dysfunction in aging brain. Department of Physiology, Faculty of Medicine, Chulalongkorn University, 2019. https://doi.org/10.58837/chula.res.2019.11.

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During advancing age, reduction of microvessels in the brain contributes insufficiency tissue perfusion. Mounting evidence indicates that microvascular deterioration in aged brain relates to oxidative stress. Nuclear factor erythroid-related factor 2 (Nrf2) plays an important role in cellular antioxidant defense. Regular physical exercise is well known to have beneficial effect to brain health, including promoted blood flow and augmented angiogenesis, in aging individuals. However, the underlying mechanism of regular physical exercise in improvement of brain microvascular density during advanc
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