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Thèses sur le sujet « CREBBP »

Auteur : Grafiati

Publié le 9 mars 2023

Mis à jour le 31 juillet 2025

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1

Dixon, Zach Adam. "The role of CREBBP mutations in lymphoid malignancies." Thesis, University of Newcastle upon Tyne, 2016. http://hdl.handle.net/10443/3556.

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Relapsed acute lymphoblastic leukaemia (ALL), diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) comprise a group of malignancies with poor prognosis and therapeutic strategies are needed to improve outcomes. Recent studies have shown that heterozygous inactivating mutations in the histone acetyl transferase, CREBBP, are frequent in these malignancies, and are thought to lead to impaired transcription of glucocorticoid (GC) response genes. Given the pivotal role of GC in the treatment of lymphoid malignancies and the finding that CREBBP mutations often arise at relapse, it has

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2

Dawes, Joanna Camilla. "Modelling Crebbp loss in BCL2 driven non-Hodgkin's lymphoma." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/58194.

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Non-Hodgkin’s lymphomas (NHL) are a spectrum of hematopoietic cancer accounting for 4% of new cancer diagnoses each year. Approximately 95% of all NHL are of B-cell origin; diffuse large B-cell lymphomas (DLBCL) and follicular lymphoma (FL) accounting for 30-40% and 20% of B-NHL respectively. Recent human mutation profiling and resequencing studies have shown that CREBBP and BCL2 are frequently mutated, early events in B-NHL that are often are concurrent. This thesis presents a study of their role in oncogenesis by generating a novel model of B-NHL overexpressing BCL2 in the haematopoetic comp

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3

BENTIVEGNA, ANGELA. "Ricerca di alterazioni del Gene CREBBP (CREB Binding Protein) in pazienti con sindrome di Rubinstein-Taybi." Bachelor's thesis, Università degli Studi di Milano-Bicocca, 2004. http://hdl.handle.net/10281/12824.

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4

Di, Dio Laura Giusy Rosaria Agata. "Sindrome da microduplicazione 16p13.3 espansione del fenotipo." Doctoral thesis, Università di Catania, 2012. http://hdl.handle.net/10761/1062.

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Le sindromi da microalterazione cromosomica sono sindromi costituzionali con ritardo mentale e anomalie fenotipiche multiple causate da sbilanci di specifiche regioni del genoma. Se il riarrangiamento cromosomico include poche megabasi viene detto criptico perché spesso non è diagnosticabile con un esame cromosomico convenzionale. Per molti anni, tuttavia, cioè fino a quando è stata disponibile solo la tecnica tradizionale e FISH per l analisi di cromosomi metafasici, erano conosciute soltanto le microdelezioni delle regioni fiancheggiate da dupliconi. La mancata diagnosi citogenetica-molec

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5

BENTIVEGNA, ANGELA. "Base molecolare della sindrome di Chromatin remodelling Rubinstein-Taybi: un sistema modello per lo studio dei deficit funzionali di acetilazione istonica." Doctoral thesis, Università degli studi di Milano, 2008. http://hdl.handle.net/10281/12823.

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Rubinstein–Taybi syndrome (RSTS) is a rare malformation disorder caused by mutations in the closely related CREBBP and EP300 genes, accounting respectively for up to 60 and 3% of cases. About 10% of CREBBP mutations are whole gene deletions often extending into flanking regions. Using FISH and microsatellite analyses as a first step in the CREBBP mutation screening of 63 Italian RSTS patients (pts), 6 deletions were identified, 3 of which were in a mosaic condition that has not been previously reported in RSTS. The clinical presentation was typical in all cases, but more severe in the three pt

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6

Camós, Guijosa Mireia. "Caracterización biológica de la leucemia mieloide aguda con translocación t(8;16)(p11;p13) y reordenamiento MYST3-CREBBP." Doctoral thesis, Universitat de Barcelona, 2007. http://hdl.handle.net/10803/2220.

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INTRODUCCIÓN. La leucemia mieloide aguda (LMA) es una enfermedad heterogénea desde el punto de vista clínico y biológico. En los últimos años se vienen reconociendo diversas alteraciones moleculares que definen entidades específicas. En este contexto, la LMA con translocación t(8;16)(p11;p13) y reordenamiento MYST3 (MOZ)/CREBBP (CBP) es una variedad infrecuente mal caracterizada desde el punto de vista biológico. <br/><br/>HIPÓTESIS Y OBJETIVOS. La proteína quimérica MYST3-CREBBP, resultante de la translocación t(8;16)(p11;p13), podría conferir a este subtipo de LMA una individualidad biológic

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7

Torres, Leuridan Cavalcante. "Avaliação da imunocompetência de portadores da síndrome de Rubinstein-taybi." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-01092008-192345/.

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A síndrome de Rubinstein-Taybi (RTS, OMIM 180849) é uma doença autossômica dominante caracterizada por dismorfismos craniofaciais típicos, polegares e háluces alargados, infecções respiratórias recidivantes, retardo mental e de crescimento. RTS está associada com mutação no gene CREBBP. Na avaliação da imunocompetência de 17 portadores de RTS, observaram-se algumas alterações na resposta imune inata e adaptativa: leucocitose persistente, neutrófilos com desgranulopoiese, elevada concentração sérica de IgM e IgG1, produção normal de anticorpos contra antígenos protéicos e anti-polissacarídeos,

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8

Djavanroodi, Faramarz. "Creep and creep-fracture crack growth." Thesis, Imperial College London, 1989. http://hdl.handle.net/10044/1/47412.

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9

Whitt, Harrison Collin. "Creep and Creep-fatigue Deformation Studies in 22V and P91 Creep-strength EnhancedFerritic Steels." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1555603135480185.

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10

Giannopoulos, Ioannis. "Creep and creep-rupture behaviour of Aramid fibres." Thesis, University of Cambridge, 2010. https://www.repository.cam.ac.uk/handle/1810/252181.

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To obtain creep-rupture data at low level within a reasonably short time-scale, two accelerated techniques have been investigated. Stepped Isothermal Method (SIM) testing involves loading a single specimen, under constant load, with the temperature increased in a series of steps to accelerate the creep. Careful choice of the temperature step and step duration allow the test to be completed in about 24 hours. At each temperature step a creep curve is obtained; these are then adjusted to compensate for the different temperature levels and a creep master curve at a reference temperature is produc

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11

Jones, J. P. "Creep and creep fracture of alpha/beta brass." Thesis, Swansea University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637455.

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The uniaxial creep and creep fracture properties of α/β brass in air, have been determined over the stress range 9MPa - 185MPa at 523-673 K, using high precision constant stress creep testing machines. In the majority of cases, normal creep curves were recorded however, under certain conditions, due to the interactions of the two constituent phases some curves exhibited two areas of primary creep. Traditional Power Law analysis was carried out, and was found to be in agreement with published data. An alternative approach, known as the θ Projection Concept accurately described the accumulation

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12

Abdallah, Zakaria. "Creep lifing methods for components under high temperature creep." Thesis, Swansea University, 2010. https://cronfa.swan.ac.uk/Record/cronfa43065.

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13

Hayes, Troy Allyn. "Creep and creep fracture of zirconium and zirconium alloys /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC IP addresses, 2004. http://wwwlib.umi.com/cr/ucsd/fullcit?p3123657.

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14

Thornton, Gail Marilyn. "Creep behaviour and creep mechanisms of normal and healing ligaments." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0023/NQ49542.pdf.

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15

Pearce, I. "Creep rupture and creep life prediction of aluminium airframe alloys." Thesis, Swansea University, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.638435.

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Aluminium alloys 2419-T851, 2124-T851 and 7010-T7351 are candidates to succeed the current airframe alloy, RR58. In the present work, high precision constant stress creep curves have been obtained for alloys 2419-T851 and 7010-T7351 over an approximate stress range 100-400MPa at 373-463K. In the case of alloy 2419-T851, the creep curves recorded were predominantly primary in nature, alloy 7010-T7351 exhibited predominantly tertiary curves, while creep curves reported <SUP>(2)</SUP> for 2124-T851 showed an intermediate curve shape. These results have been analysed to allow comparisons to be mad

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16

Ward, A. R. "Creep and creep fracture of alpha + beta titanium alloy 6.2.4.6." Thesis, Swansea University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.639344.

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High precision uniaxial constant stress creep tests were carried out at 773K for the α+β titanium alloy Ti 6.2.4.6. Repeat data at 580 MPa provided a unique opportunity to identify stochastic creep properties and to use this information to build a probabilistic creep damage assessment for this alloy. The stochastic nature of creep properties both at a single test condition (using a generalised gamma distribution) and at various test conditions (by combining this distribution with the Monkman - Grant relation) was identified. In addition, the theta prediction methodology was extended so that li

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17

Girdwood, R. B. "Creep and creep recovery of the nickel-base superalloy Nimonic 105." Thesis, Swansea University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637059.

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Uniaxial constant stress creep tests have been performed on the wrought nickel-base superalloy Nimonic 105 at 1098, 1123, 1148, 1173 and 1198K over the stress range 50-450MPa. Entire creep curves were recorded and creep curve shapes analysed. Rejuvenative procedures were applied to pre-crept samples and creep recovery quantitatively assessed.

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18

Hull, R. J. "Creep and creep fracture of the near-alpha titanium alloy IMI834." Thesis, Swansea University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637341.

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High precision uniaxial constant stress tests were carried out for the near-alpha titanium alloy IMI834. Testing was completed at 823, 848, 873, 898 and 923 K, and at stresses chosen to give rupture lives in the range of about one day to six months at each temperature. Over the entire range of testing conditions, predominantly tertiary normal creep curves were recorded. During creep an alpha-case developed at air exposed surfaces, whose depth varied according to a parabolic rate law with an activation energy of 208 kJmol<SUP>-1</SUP>. For tests failing after about 1000 hours at 848, 873 and 89

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19

Stewart, Calvin. "A Hybrid Constitutive Model For Creep, Fatigue, And Creep-Fatigue Damage." Doctoral diss., University of Central Florida, 2013. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/6023.

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In the combustion zone of industrial- and aero- gas turbines, thermomechanical fatigue (TMF) is the dominant damage mechanism. Thermomechanical fatigue is a coupling of independent creep, fatigue, and oxidation damage mechanisms that interact and accelerate microstructural degradation. A mixture of intergranular cracking due to creep, transgranular cracking due to fatigue, and surface embrittlement due to oxidation is often observed in gas turbine components removed from service. The current maintenance scheme for gas turbines is to remove components from service when any criteria (elongation,

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20

Lieu, T. D. "Creep and creep fracture of MA 957 oxide dispersion-strengthened ferritic steel." Thesis, Swansea University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637910.

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The creep and creep fatigue properties of a 14% Cr ferritic steel (MA 957) strengthened with a dispersion of Y<SUB>2</SUB>O<SUB>3</SUB> particles have been determined using high precision constant stress creep machines. Creep testing was carried out under tension over a stress range of 250 to 420 MPa at 873 to 973K. In addition, compression creep tests were also performed over a stress range of 250 to 320 MPa at 948K. Normal creep curves were observed under all tensile conditions, i.e. after the initial strain on loading, the strain rate decreased to an apparently steady state before the onset

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21

Havel, Frantisek. "Creep in soft Soils." Doctoral thesis, Norwegian University of Science and Technology, Faculty of Engineering Science and Technology, 2004. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-297.

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<p>As more and more constructions are concentrated in densely populated urban areas, there is an increasing need to construct buildings and geotechnical structures on soft clay materials, which usually produce significant creep deformation. Although a lot of research work has been related to the creep behaviour of a natural clay material, there are still many questions about this phenomenon. Even today, prediction of the time dependent deformation is generally very problematic. Detailed laboratory, in-situ and numerical studies of soft soil creep are necessary for the better understanding and

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22

Feng, Gang, and 封剛. "Creep effects in nanoindentation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31224350.

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23

Resen, Abdul-Amir S. "Biaxial creep of plastics." Thesis, University of Manchester, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.256753.

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24

Liu, Qida. "Electromechanical creep in ferroelectrics." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613330.

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25

Feng, Gang. "Creep effects in nanoindentation." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23273288.

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26

Yu, Chi-Wen. "Creep characteristics of soft rock and modelling of creep in tunnel : determination of creep characteristics of soft rock and development of non-linear creep analysis code for squeezing tunnel problem." Thesis, University of Bradford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.586717.

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Squeezing or time-dependent creep deformation of rock has been encountered frequently in tunnels. It is particularly common in tunnels excavated in very soft rock or heavily fractured rock under significant in-situ stresses. In Taiwan, due to the inferior geological setting and the young sedimentary rock formations, squeezing in tunnels was found to be a very common problem from the recent case histories of some large span road tunnels. This research reviewed the existing rock creep models, and an adequate creep model for representing the creep behaviour of soft rock or a weak rock mass in gen

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27

DeMaio, Andrew Marc. "The Role of Bonding on the Tensile Creep Behavior of Paper." Diss., Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/16329.

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The role of bonding in the tensile creep behavior of paper was analyzed. This was accomplished by producing handsheets at a range of different bonding levels through manipulation of relative bonded area and specific bond strength. This was done by varying the level of wet pressing (to change relative bonded area) and using debonding and bonding agents (to change specific bond strength). Once manufactured, sheets underwent an extensive battery of physical testing and creep testing. Creep testing was conducted under constant humidity and cyclic humidity (accelerated creep) conditions. Microscopi

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Palmer, C. J. "High temperature creep of copper." Thesis, Swansea University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.638403.

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The key observations that have underpinned traditional power law approaches to creep mechanism identification have been re-evaluated using information obtained for pure copper and aluminium, and also for various other metals and alloys. Specifically, data is presented which show stress/creep rate plots for copper and aluminium over extended stress ranges to be well represented by continuous curves, contradicting the common assumption that a transition in mechanisms occurs as the stress is reduced. Data is also presented from a series of stress interruption tests on pure copper, with strain/str

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Wang, D. "Creep of 316 stainless steel." Thesis, Swansea University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.639338.

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Constant stress creep tests were carried out for 316 stainless steel at 550, 600, 650 and 700<SUP>o</SUP>C over the stress range of 125 - 500 MPa. Entire creep curves were recorded by computer and creep curve shapes analysed. Within the stress and temperature range of the test matrix, creep curve shapes vary from tertiary dominant at low stress and temperature, to primary dominant at high temperature and mixed type at intermediate temperatures. Traditional parametric methods such as Larson-Miller, Orr-Dorn-Sherby and Manson-Succop methods were applied for the analysis of creep rupture life. Th

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30

Sun, Wei. "Creep of service-aged welds." Thesis, University of Nottingham, 1996. http://eprints.nottingham.ac.uk/11727/.

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The creep behaviour of welds in service-aged pipes are studied. The aims of the research have been achieved using analytical, numerical and experimental approaches to the relevant subjects. Several features of the work are presented: (i) a systematic parametric study of the creep of two-material test specimens including a stress singularity analysis, (ii) an impression creep testing method using a rectangular indenter, which can be applied to study the creep properties in welds, and (iii) methods used for damage constitutive equation generation involving FE-damage modelling of the rupture test

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Rayner, Glen. "Creep of welded branched pipes." Thesis, University of Nottingham, 2004. http://eprints.nottingham.ac.uk/11660/.

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Creep failure of welds in high-temperature power plant steam piping systems is known to be a potential cause of plant failure. Creep behaviour of plain pipes with circumferential welds and cross-weld specimens have received fairly extensive attention. However, research into the creep behaviour of welded thick-walled branched steam pipes has received less attention. Consequently, this thesis addresses improving the understanding of the creep behaviour for this type of geometry. Numerical and analytical methods are used to assess the creep behaviour of typical power plant branched pipe geometrie

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32

Ling, Paul Keh Yiing. "Creep of metal matrix composites." Thesis, University of Nottingham, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240496.

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Kwok, Chung Yee. "Micromechanical modelling of soil creep." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611185.

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De, Voy Julian David James. "Failure of creep brittle materials." Thesis, University of Leicester, 1993. http://hdl.handle.net/2381/34757.

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Maraboli, Contardo Luis Robinson. "Creep de aleaciones cobre molibdeno." Tesis, Universidad de Chile, 2015. http://repositorio.uchile.cl/handle/2250/132918.

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Ingeniero Civil Mecánico<br>Esta memoria consiste en una investigación en la cual se busca mejorar las propiedades mecánicas del cobre, incorporando una dispersión nanométrica de cerámicos in-situ, mediante molienda reactiva, los cuales dificultan el movimiento de dislocaciones y límites de grano. Este trabajo tiene por objetivo fabricar aleaciones con dispersión de carburos de molibdeno (específicamente Cu - 0%v Mo2C, Cu - 2,5%v Mo2C y Cu - 5%v Mo2C) y determinar cómo afecta esta composición en la compresión en caliente y creep. Se realizaron moliendas reactivas de 100 y 150 horas, a partir

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Couto, Marcelo Guerino Pereira. "'Creep' em resinas compostas fotopolimerizáveis." Universidade de São Paulo, 2000. http://www.teses.usp.br/teses/disponiveis/25/25131/tde-11032005-110757/.

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As resinas compostas vêm sofrendo inúmeras alterações com o objetivo de tornar o seu uso adequado para restaurações de dentes posteriores, entretanto, problemas clínicos associados à sua utilização são comumente observados, dentre eles sua resistência ao desgaste e à abrasão, a contração de polimerização, a microinfiltrção marginal, e sua deformação permanente (importante propriedade em situações clínicas onde existem áreas sujeitas às forças oclusais) e esta, normalmente não é considerada. Visando determinar o creep, por meio da deformação permanente, amostras confeccionadas com resinas com

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Sieburg, H. O. "Creep predictions for turbomachinery components." Master's thesis, University of Cape Town, 1989. http://hdl.handle.net/11427/18697.

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Several theories of creep and creep rupture are reviewed. Specific attention is devoted to the brittle damage theory proposed by Kachanov. Creep, damage and life predictions for rectangular or circular cross section beams under bending and tensile loads are presented. Comparison with data for a Ni Superalloy showed life predictions could be 30X in excess of experimental values. This beam model also revealed that it is imperative that no bending moments be inadvertently applied during tensile creep testing. The creep-damage material model is extended to multidimensional situations. A refinement

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Neuhofer, Erik Joachim, and af Rolén Samuel Zelenka. "The Feature Creep Perception in Game Development : Exploring the role of feature creep in development methods and employee engagement." Thesis, Södertörns högskola, Medieteknik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-44946.

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Game developers often find themselves coming up with ideas along the production period of a game varying in size and may go unnoticed or seem insignificant to the scope of the project but in the long run add up to break deadlines, budget and affect the morale and engagement of developers. In the modern game development industry agile development methods have increased in popularity allowing flexibility in the development process. This agile approach has emerged from traditional software development where waterfall development methods are common practice (Kanode and Haddad, 2009). Through in-de

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Larsson, Jonas. "Evaluation of current methods for creep analysis and impression creep testing of power plant steels." Thesis, KTH, Materialvetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-104603.

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Destructive testing of creep exposed components is a powerful tool for evaluation of remaining lifetime of high temperature pipe systems. The most common destructive evaluation method used today is uniaxial creep testing. Uniaxial creep tests can produce accurate creep curves but the test method has some drawbacks such as costliness and long testing times. It also demands large sample material outtake which often involve weld repair. Impression creep (IC) testing is a relatively new alternative test method for evaluating primary and secondary creep rates. The scope of this work is to evaluate

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40

Stracey, Muhammad Ghalib. "Continuum Damage Mechanics (CDM) modelling of dislocation creep in 9-12% Cr creep resistant steels." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/22994.

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The generation of electricity to meet an ever-growing demand has become a defining characteristic of the modern world for both developed and developing nations alike. This, coupled with the intensifying concern with pollution and its effects on the environment has put immense pressure on how quickly and efficiently power is produced. Being the most prevalent source of electricity generation, coal fired power plants have been subject to increasing scrutiny and study in an effort to improve the efficiency at which they operate. Hence, coal fired power plants are being run at increased temperatur

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41

Chang, Yeou Shin. "The effect of the interphase/interface region on creep and creep rupture of thermoplastic composites." Diss., This resource online, 1992. http://scholar.lib.vt.edu/theses/available/etd-06062008-170854/.

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42

Chakravarty, Sanjay. "DEVELOPMENT OF CREEP TESTER AND TO INVESTIGATE THE EFFECT OF CATIONIC STARCH ON TENSILE CREEP ON SOFTWOOD BLEACHED KRAFT HANDSHEETS AT CONSTANT HUMIDITY." Miami University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=miami1143250391.

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43

Zhang, Ruomeng. "Evaluation of Current Concrete Creep Prediction Models." University of Toledo / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1461963600.

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44

Saber, Mohammed. "Experimental and finite element studies of creep and creep crack growth in P91 and P92 weldments." Thesis, University of Nottingham, 2011. http://eprints.nottingham.ac.uk/12197/.

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P91 and P92 steels are two ASTM grades of steel which have been used in high temperature applications, such as fossil-fuelled power stations, nuclear power stations and chemical plants. Operating under creep conditions, i.e. high temperature and/or high stress, the welds made from these steels are potential failure locations and, therefore, life limiting for the entire plant. In this thesis, the results of creep and creep crack growth (CCG) tests, which were carried out on P91 and P92 welds, are reported. These tests were carried out on welds constituents, i.e. parent materials (PM) and weld m

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Li, Han. "The nanoindentation size effects of creep." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B30696380.

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Segle, Peter. "Numerical simulation of weldment creep response." Doctoral thesis, KTH, Materials Science and Engineering, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3359.

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<p>In-service inspections of high temperature pressureequipment show that weldments are prone to creep and fatiguedamage. It is not uncommon that severely damaged weldments arefound even before the design life of the component has beenreached. In order to improve this situation action has beentaken during the last decades, both from industry, universitiesand research institutes, aiming at an enhanced understanding ofthe weldment response.</p><p>The work presented in this thesis focuses on numericalsimulation of weldment creep response. For a more profoundunderstanding of the evolution of creep

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Magnusson, Hans. "Creep modelling of particle strengthened steels." Doctoral thesis, KTH, Materialteknologi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-12235.

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Materials used in thermal power plants have to resist creep deformation for time periods up to 30 years. Material evaluation is typically based on creep testing with a maximum duration of a few years. This information is used as input when empirically deriving models for creep. These kinds of models are of limited use when considering service conditions or compositions different from those in the experiments. In order to provide a more general model for creep, the mechanisms that give creep strength have to be identified and fundamentally described. By combining tools for thermodynamic modelli

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Olagne, Xavier. "An engineering model for snow creep." Thesis, University of British Columbia, 1989. http://hdl.handle.net/2429/27609.

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Snowcovers on slopes densify and deform continuously throughout the winter. These slow, mainly viscous deformations are known as snow creep and this thesis presents an attempt to model them by idealizing snow as a non-Newtonian fluid, where the bulk and shear viscosities depend upon both stress and density. A three-dimensional constitutive law is developed, based largely on analogy with the flow behavior of ice and soil materials. The model, primarily intended for engineering applications (design of structures erected in a deep snowpack), is tested for creep pressures on long rigid obstacles.

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Van, Steenis Karen Anne. "Modelling creep deformation in floating ice." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ60509.pdf.

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Magnusson, Hans. "Creep modelling of particle strengthened steels." Licentiate thesis, Stockholm : Kungliga Tekniska högskolan, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4436.

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