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Articles de revues sur le sujet « Data censoring »

Auteur : Grafiati

Publié le 14 mars 2023

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1

Moradian, Hoora, Denis Larocque, and François Bellavance. "Survival forests for data with dependent censoring." Statistical Methods in Medical Research 28, no. 2 (2017): 445–61. http://dx.doi.org/10.1177/0962280217727314.

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Tree-based methods are very powerful and popular tools for analysing survival data with right-censoring. The existing methods assume that the true time-to-event and the censoring times are independent given the covariates. We propose different ways to build survival forests when dependent censoring is suspected, by using an appropriate estimator of the survival function when aggregating the individual trees and/or by modifying the splitting rule. The appropriate estimator used in this paper is the copula-graphic estimator. We also propose a new method for building survival forests, called p-fo

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Willems, SJW, A. Schat, MS van Noorden, and M. Fiocco. "Correcting for dependent censoring in routine outcome monitoring data by applying the inverse probability censoring weighted estimator." Statistical Methods in Medical Research 27, no. 2 (2016): 323–35. http://dx.doi.org/10.1177/0962280216628900.

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Censored data make survival analysis more complicated because exact event times are not observed. Statistical methodology developed to account for censored observations assumes that patients’ withdrawal from a study is independent of the event of interest. However, in practice, some covariates might be associated to both lifetime and censoring mechanism, inducing dependent censoring. In this case, standard survival techniques, like Kaplan–Meier estimator, give biased results. The inverse probability censoring weighted estimator was developed to correct for bias due to dependent censoring. In t

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Emura, Takeshi, and Yi-Hau Chen. "Gene selection for survival data under dependent censoring: A copula-based approach." Statistical Methods in Medical Research 25, no. 6 (2016): 2840–57. http://dx.doi.org/10.1177/0962280214533378.

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Dependent censoring arises in biomedical studies when the survival outcome of interest is censored by competing risks. In survival data with microarray gene expressions, gene selection based on the univariate Cox regression analyses has been used extensively in medical research, which however, is only valid under the independent censoring assumption. In this paper, we first consider a copula-based framework to investigate the bias caused by dependent censoring on gene selection. Then, we utilize the copula-based dependence model to develop an alternative gene selection procedure. Simulations s

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Sparks, R. S., G. Sutton, P. Toscas, and J. T. Ormerod. "Modelling Inverse Gaussian Data with Censored Response Values: EM versus MCMC." Advances in Decision Sciences 2011 (July 5, 2011): 1–8. http://dx.doi.org/10.1155/2011/571768.

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Low detection limits are common in measure environmental variables. Building models using data containing low or high detection limits without adjusting for the censoring produces biased models. This paper offers approaches to estimate an inverse Gaussian distribution when some of the data used are censored because of low or high detection limits. Adjustments for the censoring can be made if there is between 2% and 20% censoring using either the EM algorithm or MCMC. This paper compares these approaches.

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Sun, Yanqing, and Jimin Lee. "Testing independent censoring for longitudinal data." Statistica Sinica 21, no. 3 (2011): 1315–39. http://dx.doi.org/10.5705/ss.2009.251.

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D’Arrigo, Graziella, Daniela Leonardis, Samar Abd ElHafeez, Maria Fusaro, Giovanni Tripepi, and Stefanos Roumeliotis. "Methods to Analyse Time-to-Event Data: The Kaplan-Meier Survival Curve." Oxidative Medicine and Cellular Longevity 2021 (September 20, 2021): 1–7. http://dx.doi.org/10.1155/2021/2290120.

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Studies performed in the field of oxidative medicine and cellular longevity frequently focus on the association between biomarkers of cellular and molecular mechanisms of oxidative stress as well as of aging, immune function, and vascular biology with specific time to event data, such as mortality and organ failure. Indeed, time-to-event analysis is one of the most important methodologies used in clinical and epidemiological research to address etiological and prognostic hypotheses. Survival data require adequate methods of analyses. Among these, the Kaplan-Meier analysis is the most used one

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Gómez, Guadalupe, M. Luz Calle, Ramon Oller, and Klaus Langohr. "Tutorial on methods for interval-censored data and their implementation in R." Statistical Modelling 9, no. 4 (2009): 259–97. http://dx.doi.org/10.1177/1471082x0900900402.

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Interval censoring is encountered in many practical situations when the event of interest cannot be observed and it is only known to have occurred within a time window. The theory for the analysis of interval-censored data has been developed over the past three decades and several reviews have been written. However, it is still a common practice in medical and reliability studies to simplify the interval censoring structure of the data into a more standard right censoring situation by, for instance, imputing the midpoint of the censoring interval. The availability of software for right censori

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Nagy, M., and Adel Fahad Alrasheedi. "Estimations of Generalized Exponential Distribution Parameters Based on Type I Generalized Progressive Hybrid Censored Data." Computational and Mathematical Methods in Medicine 2022 (March 29, 2022): 1–15. http://dx.doi.org/10.1155/2022/8058473.

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Type I generalized progressive hybrid censoring scheme is a combination of Type I and Type II progressive hybrid censoring schemes, and it is one of the most recent advancements in data censoring. In this article, based on Type I generalized progressive hybrid censoring data from generalized exponential distribution, the maximum likelihood and Bayesian estimators of distribution’s parameters as well as the reliability and hazard functions are approximately calculated. Also, the credible interval estimators of these quantities are obtained. Since these quantities cannot be obtained in closed fo

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Belviso, Nicholas, Yichi Zhang, Herbert D. Aronow, et al. "Addressing Posttreatment Selection Bias in Comparative Effectiveness Research, Using Real-World Data and Simulation." American Journal of Epidemiology 191, no. 2 (2021): 331–40. http://dx.doi.org/10.1093/aje/kwab242.

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Abstract To examine methodologies that address imbalanced treatment switching and censoring, 6 different analytical approaches were evaluated under a comparative effectiveness framework: intention-to-treat, as-treated, intention-to-treat with censor-weighting, as-treated with censor-weighting, time-varying exposure, and time-varying exposure with censor-weighting. Marginal structural models were employed to address time-varying exposure, confounding, and possibly informative censoring in an administrative data set of adult patients who were hospitalized with acute coronary syndrome and treated

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Belviso, Nicholas, Yichi Zhang, Herbert D. Aronow, et al. "Addressing Posttreatment Selection Bias in Comparative Effectiveness Research, Using Real-World Data and Simulation." American Journal of Epidemiology 191, no. 2 (2021): 331–40. http://dx.doi.org/10.1093/aje/kwab242.

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Abstract To examine methodologies that address imbalanced treatment switching and censoring, 6 different analytical approaches were evaluated under a comparative effectiveness framework: intention-to-treat, as-treated, intention-to-treat with censor-weighting, as-treated with censor-weighting, time-varying exposure, and time-varying exposure with censor-weighting. Marginal structural models were employed to address time-varying exposure, confounding, and possibly informative censoring in an administrative data set of adult patients who were hospitalized with acute coronary syndrome and treated

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Yu, Mengzhu, Yanqin Feng, Ran Duan, and Jianguo Sun. "Regression analysis of multivariate interval-censored failure time data with informative censoring." Statistical Methods in Medical Research 31, no. 3 (2021): 391–403. http://dx.doi.org/10.1177/09622802211061668.

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Regression analysis of multivariate interval-censored failure time data has been discussed by many authors1–6. For most of the existing methods, however, one limitation is that they only apply to the situation where the censoring is non-informative or the failure time of interest is independent of the censoring mechanism. It is apparent that this may not be true sometimes and as pointed out by some authors, the analysis that does not take the dependent censoring into account could lead to biased or misleading results7,8. In this study, we consider regression analysis of multivariate interval-c

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Hyun, Seunggeun, Jimin Lee, and Robert Yearout. "Parameter Estimation of Type-I and Type-II Hybrid Censored Data from the Log-Logistic Distribution." Industrial and Systems Engineering Review 4, no. 1 (2016): 37–44. http://dx.doi.org/10.37266/iser.2016v4i1.pp37-44.

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In experiments on product lifetime and reliability testing, there are many practical situations in which researchers terminate the experiment and report the results before all items of the experiment fail because of time or cost consideration. The most common and popular censoring schemes are type-I and type-II censoring. In type-I censoring scheme, the termination time is pre-fixed, but the number of observed failures is a random variable. However, if the mean lifetime of experimental units is somewhat larger than the pre-fixed termination time, then far fewer failures would be observed and t

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Leurgans, Sue. "Linear Models, Random Censoring and Synthetic Data." Biometrika 74, no. 2 (1987): 301. http://dx.doi.org/10.2307/2336144.

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Helsel, Dennis R. "Insider Censoring: Distortion of Data with Nondetects." Human and Ecological Risk Assessment: An International Journal 11, no. 6 (2005): 1127–37. http://dx.doi.org/10.1080/10807030500278586.

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Wang, Mei-Cheng, Jing Qin, and Chin-Tsang Chiang. "Analyzing Recurrent Event Data With Informative Censoring." Journal of the American Statistical Association 96, no. 455 (2001): 1057–65. http://dx.doi.org/10.1198/016214501753209031.

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Zhu, Hongbin, Hua Qian, Xiliang Luo, and Yang Yang. "Adaptive Queuing Censoring for Big Data Processing." IEEE Signal Processing Letters 25, no. 5 (2018): 610–14. http://dx.doi.org/10.1109/lsp.2018.2815006.

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Jammalamadaka, S. Rao, and Vasudevan Mangalam. "A general censoring scheme for circular data." Statistical Methodology 6, no. 3 (2009): 280–89. http://dx.doi.org/10.1016/j.stamet.2008.10.002.

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Rabinowitz, Daniel. "Testing current status data for dependent censoring." Statistics & Probability Letters 48, no. 3 (2000): 213–16. http://dx.doi.org/10.1016/s0167-7152(99)00202-3.

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Fennie, Kristopher P., Carol A. Bova, and Ann B. Williams. "Adjusting and Censoring Electronic Monitoring Device Data." JAIDS Journal of Acquired Immune Deficiency Syndromes 43, Supplement 1 (2006): S88—S95. http://dx.doi.org/10.1097/01.qai.0000248336.97814.2f.

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Kim, Jin-Heum, and Youn-Nam Kim. "Analysis of Tumorigenicity Data with Informative Censoring." Korean Journal of Applied Statistics 23, no. 5 (2010): 871–82. http://dx.doi.org/10.5351/kjas.2010.23.5.871.

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SUE, LEURGANS. "Linear models, random censoring and synthetic data." Biometrika 74, no. 2 (1987): 301–9. http://dx.doi.org/10.1093/biomet/74.2.301.

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Santos, Jesús Basulto, and Francisco Javier Ortega Irizo. "Modelling citation age data with right censoring." Scientometrics 62, no. 3 (2005): 329–42. http://dx.doi.org/10.1007/s11192-005-0025-5.

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Abdushukurov, A. A. "Extension of Relative-Risk Power Estimator under Dependent Random Censored Data." Contemporary Mathematics. Fundamental Directions 68, no. 1 (2022): 1–13. http://dx.doi.org/10.22363/2413-3639-2022-68-1-1-13.

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In this paper, the considered problem consists in estimation of conditional survival function by right random censoring model in the presence of a covariate. We propose a new estimator of conditional survival function which is extension of relative-risk power estimator of independent censoring and study its large sample properties. We present result of asymptotic normality with the same limiting Gaussian process as for copula-graphic estimator.

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24

Jayalath, Kalanka P. "Fiducial Inference on the Right Censored Birnbaum–Saunders Data via Gibbs Sampler." Stats 4, no. 2 (2021): 385–99. http://dx.doi.org/10.3390/stats4020025.

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In this article, we implement a flexible Gibbs sampler to make inferences for two-parameter Birnbaum–Saunders (BS) distribution in the presence of right-censored data. The Gibbs sampler is applied on the fiducial distributions of the BS parameters derived using the maximum likelihood, methods of moments, and their bias-reduced estimates. A Monte-Carlo study is conducted to make comparisons between these estimates for Type-II right censoring with various parameter settings, sample sizes, and censoring percentages. It is concluded that the bias-reduced estimates outperform the rest with increasi

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Bakoban, R. A., and G. A. Abd-Elmougod. "MCMC in Analysis of Progressively First Failure Censored Competing Risks Data for Gompertz Model." Journal of Computational and Theoretical Nanoscience 13, no. 10 (2016): 6662–70. http://dx.doi.org/10.1166/jctn.2016.5612.

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In medical studies or in reliability analysis, it is quite common that the failure of any individual or any item may be attributable to more than one cause. So in this paper, we consider the competing risks model with very general censoring scheme, namely progressive first-failure censored scheme under the Gompertz life time distribution. The results in each of first-failure censoring, progressive Type II censoring, Type II censoring and complete sample are a special cases. We provide different methods for the analysis of the model under the assumption of independent causes of failure and Gomp

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Jaffa, Miran A., Mulugeta Gebregziabher, and Ayad A. Jaffa. "Shared parameter and copula models for analysis of semicontinuous longitudinal data with nonrandom dropout and informative censoring." Statistical Methods in Medical Research 31, no. 3 (2021): 451–74. http://dx.doi.org/10.1177/09622802211060519.

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Analysis of longitudinal semicontinuous data characterized by subjects’ attrition triggered by nonrandom dropout is complex and requires accounting for the within-subject correlation, and modeling of the dropout process. While methods that address the within-subject correlation and missing data are available, approaches that incorporate the nonrandom dropout, also referred to informative right censoring, in the modeling step are scarce due to the computational intensity and possible intractable integration needed for its implementation. Appreciating the complexity of this problem and the need

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Prakash, Gyan. "Bound lengths for type-I progressive hybrid burr type-XII censored data under SS-PALT." Biometrics & Biostatistics International Journal 10, no. 1 (2021): 4–22. http://dx.doi.org/10.15406/bbij.2021.10.00325.

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Our main focus on combining two different approaches, Step-Stress Partially Accelerated Life Test and Type-I Progressive Hybrid censoring criteria in the present article. The fruitfulness of this combination has been investigated by bound lengths for unknown parameters of the Burr Type-XII distribution. Approximate confidence intervals, Bootstrap confidence intervals and One-Sample Bayes prediction bound lengths have been obtained under the above scenario. Particular cases of Type-I Progressive Hybrid censoring (Type-I and Progressive Type-II censoring) has also evaluated under SS-PALT. Optima

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Sigelman, Lee, and Langche Zeng. "Analyzing Censored and Sample-Selected Data with Tobit and Heckit Models." Political Analysis 8, no. 2 (1999): 167–82. http://dx.doi.org/10.1093/oxfordjournals.pan.a029811.

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Political scientists are making increasing use of the Tobit and Heckit models. This paper addresses some common problems in the application and interpretation of these models. Through numerical experiments and reanalysis of data from a study by Romer and Snyder (1994), we illustrate the consequences of using the standard Tobit model, which assumes a censoring point at zero, when the zeros are not due to censoring mechanisms or when actual censoring is not at zero. In the latter case, we also show that Greene's (1981) well-known results on the direction and size of the bias of the OLS estimator

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Khoolenjani, N. B., and O. Chatrabgoun. "Estimating the parameters of lifetime distributions under progressively Type-II censoring from fuzzy data." Journal of Applied Mathematics, Statistics and Informatics 12, no. 1 (2016): 41–53. http://dx.doi.org/10.1515/jamsi-2016-0004.

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Abstract The problem of estimating lifetime distribution parameters under progressively Type-II censoring originated in the context of reliability. But traditionally it is assumed that the available data from this censoring scheme are performed in exact numbers. However, some collected lifetime data might be imprecise and are represented in the form of fuzzy numbers. Thus, it is necessary to generalize classical statistical estimation methods for real numbers to fuzzy numbers. This paper deals with the estimation of lifetime distribution parameters under progressively Type-II censoring scheme

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Lone, Showkat Ahmad, Ahmadur Rahman, and Tanveer A. Tarray. "Inference for Step-Stress Partially Accelerated Life Test Model with an Adaptive Type-I Progressively Hybrid Censored Data." Journal of Modern Applied Statistical Methods 19, no. 1 (2021): 2–20. http://dx.doi.org/10.22237/jmasm/1608552180.

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Consider estimating data of failure times under step-stress partially accelerated life tests based on adaptive Type-I hybrid censoring. The mathematical model related to the lifetime of the test units is assumed to follow Rayleigh distribution. The point and interval maximum-likelihood estimations are obtained for distribution parameter and tampering coefficient. Also, the work is conducted under a traditional Type-I hybrid censoring plan (scheme). A Monte Carlo simulation algorithm is used to evaluate and compare the performances of the estimators of the tempering coefficient and model parame

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Sadler, William A. "Methods comparison biases due to differing uncertainties and data censoring." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 56, no. 5 (2019): 608–12. http://dx.doi.org/10.1177/0004563219859920.

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Background Measurements on clinical specimens that contain no analyte, or very low amounts of analyte, unavoidably generate assay response (signal) measurements that fall on the ‘negative’ side of the fitted zero response. It is virtually universal practice to left-censor such measurements to zero and this is frequently extended by left-censoring to the assay limit of detection (LoD) value for reporting purposes. This study considers the effect of censoring on methods comparison analysis. Methods Paired results were randomly generated from two hypothetical assays with zero bias, firstly assumi

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Rogula, Basia, Greta Lozano-Ortega, and Karissa M. Johnston. "A Method for Reconstructing Individual Patient Data From Kaplan-Meier Survival Curves That Incorporate Marked Censoring Times." MDM Policy & Practice 7, no. 1 (2022): 238146832210776. http://dx.doi.org/10.1177/23814683221077643.

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Introduction. Access to individual patient data (IPD) can be advantageous when conducting cost-effectiveness analyses or indirect treatment comparisons. While exact times of censoring are often marked on published Kaplan-Meier (KM) curves, an algorithm for reconstructing IPD from such curves that allows for their incorporation is presently unavailable. Methods. An algorithm capable of incorporating marked censoring times was developed to reconstruct IPD from KM curves, taking as additional inputs the total patient count and coordinates of the drops in survival. The reliability of the algorithm

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Dagne, Getachew A., and Yangxin Huang. "Mixed-Effects Tobit Joint Models for Longitudinal Data with Skewness, Detection Limits, and Measurement Errors." Journal of Probability and Statistics 2012 (2012): 1–19. http://dx.doi.org/10.1155/2012/614102.

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Complex longitudinal data are commonly analyzed using nonlinear mixed-effects (NLME) models with a normal distribution. However, a departure from normality may lead to invalid inference and unreasonable parameter estimates. Some covariates may be measured with substantial errors, and the response observations may also be subjected to left-censoring due to a detection limit. Inferential procedures can be complicated dramatically when such data with asymmetric characteristics, left censoring, and measurement errors are analyzed. There is relatively little work concerning all of the three feature

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Bakoyannis, Giorgos, and Giota Touloumi. "Practical methods for competing risks data: A review." Statistical Methods in Medical Research 21, no. 3 (2011): 257–72. http://dx.doi.org/10.1177/0962280210394479.

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Competing risks data arise naturally in medical research, when subjects under study are at risk of more than one mutually exclusive event such as death from different causes. The competing risks framework also includes settings where different possible events are not mutually exclusive but the interest lies on the first occurring event. For example, in HIV studies where seropositive subjects are receiving highly active antiretroviral therapy (HAART), treatment interruption and switching to a new HAART regimen act as competing risks for the first major change in HAART. This article introduces c

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Chen, Xiaotian, Yu Cheng, Ellen Frank, and David J. Kupfer. "Association analysis of successive events data in the presence of competing risks." Statistical Methods in Medical Research 27, no. 6 (2016): 1661–82. http://dx.doi.org/10.1177/0962280216667645.

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We aim to close a methodological gap in analyzing durations of successive events that are subject to induced dependent censoring as well as competing-risk censoring. In the Bipolar Disorder Center for Pennsylvanians study, some patients who managed to recover from their symptomatic entry later developed a new depressive or manic episode. It is of great clinical interest to quantify the association between time to recovery and time to recurrence in patients with bipolar disorder. The estimation of the bivariate distribution of the gap times with independent censoring has been well studied. Howe

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Seong, Yeongjae, and Kyeongjun Lee. "Exact Likelihood Inference for Parameter of Exponential Distribution under Combined Generalized Progressive Hybrid Censoring Scheme." Symmetry 14, no. 9 (2022): 1764. http://dx.doi.org/10.3390/sym14091764.

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Recently, the generalized type I progressive hybrid censoring scheme (GenT1PrHyCS) and generalized type II progressive hybrid censoring scheme (GenT2PrHyCS) have become quite popular in reliability studies. These two type censoring schemes are very complex due to the large number of parameters used to specify the censoring procedure. Therefore, in this paper, we consider a more general and more complex new censoring scheme. Also, we consider the exponential distribution(ExpD) and derive an expression for the density function of the MLE. We prove the exact distribution of the maximum likelihood

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Dey, Tanujit, Stuart R. Lipsitz, Zara Cooper, Quoc-Dien Trinh, Martin Krzywinski, and Naomi Altman. "Survival analysis—time-to-event data and censoring." Nature Methods 19, no. 8 (2022): 906–8. http://dx.doi.org/10.1038/s41592-022-01563-7.

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Drobeniuc, Ana-Maria, and Anne Spaulding. "Censoring of HIV Viremia Data of Reincarcerated Individuals." JAIDS Journal of Acquired Immune Deficiency Syndromes 76, no. 1 (2017): e22-e23. http://dx.doi.org/10.1097/qai.0000000000001465.

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Jiang, Thomas J., and James M. Dickey. "Bayesian methods for categorical data under informative censoring." Bayesian Analysis 3, no. 3 (2008): 541–53. http://dx.doi.org/10.1214/08-ba321.

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Datta, Somnath. "Robust Regression Analysis of Longitudinal Data under Censoring." Austrian Journal of Statistics 46, no. 3-4 (2017): 3–11. http://dx.doi.org/10.17713/ajs.v46i3-4.666.

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We consider regression analysis of longitudinal data when the temporal correlation is modeled by an autoregressive process. Robust R estimators of regression and autoregressive parameters are obtained. Our estimators are valid under censoring caused by detection limits. Efficient computation of the estimators is discussed. Theoretical and simulation studies of the estimators are presented. We analyze a real data set on air pollution using our methodology.

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de Oliveira, Guilherme Lopes, Rosangela Helena Loschi, and Renato Martins Assunção. "A random-censoring Poisson model for underreported data." Statistics in Medicine 36, no. 30 (2017): 4873–92. http://dx.doi.org/10.1002/sim.7456.

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Khan, Shakeeb, Maria Ponomareva, and Elie Tamer. "Identification of panel data models with endogenous censoring." Journal of Econometrics 194, no. 1 (2016): 57–75. http://dx.doi.org/10.1016/j.jeconom.2016.01.010.

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Nur Niswah Naslina, Azid Maarof, Arasan Jayanthi, Zulkafli Hani Syahida, and Adam Mohd Bakri. "Assessing the Goodness of Fit of the Gompertz Model in the Presence of Right and Interval Censored Data with Covariate." Austrian Journal of Statistics 49, no. 3 (2020): 57–71. http://dx.doi.org/10.17713/ajs.v49i3.1085.

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This research focuses on assessing the goodness of fit for the Gompertz model in the presence of right and interval censored data with covariate. The performance of the maximum likelihood estimates was evaluated via a simulation study at various censoring proportions and sample sizes. The conclusions were drawn based on the results of bias, standard error and root mean square error at different settings. Following that, another simulation study was carried out to compare the performance of the proposed modifications to the Cox-Snell residuals for both censored and uncensored observations at di

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Lin, Hung-Mo. "Informative Censoring—A Cause of Bias in Estimating COVID-19 Mortality Using Hospital Data." Life 13, no. 1 (2023): 210. http://dx.doi.org/10.3390/life13010210.

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(1) Background: Several retrospective observational analyzed treatment outcomes for COVID-19; (2) Methods: Inverse probability of censoring weighting (IPCW) was applied to correct for bias due to informative censoring in database of hospitalized patients who did and did not receive convalescent plasma; (3) Results: When compared with an IPCW analysis, overall mortality was overestimated using an unadjusted Kaplan–Meier curve, and hazard ratios for the older age group compared to the youngest were underestimated using the Cox proportional hazard models and 30-day mortality; (4) Conclusions: An

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Jackson, John W. "Diagnosing Covariate Balance Across Levels of Right-Censoring Before and After Application of Inverse-Probability-of-Censoring Weights." American Journal of Epidemiology 188, no. 12 (2019): 2213–21. http://dx.doi.org/10.1093/aje/kwz136.

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Abstract Covariate balance is a central concept in the potential outcomes literature. With selected populations or missing data, balance across treatment groups can be insufficient for estimating marginal treatment effects. Recently, a framework for using covariate balance to describe measured confounding and selection bias for time-varying and other multivariate exposures in the presence of right-censoring has been proposed. Here, we revisit this framework to consider balance across levels of right-censoring over time in more depth. Specifically, we develop measures of covariate balance that

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Bagust, Adrian, and Sophie J. Beale. "Exploring the Effects of Early Censoring and Analysis of Clinical Trial Survival Data on Effectiveness and Cost-effectiveness Estimation through a Case Study in Advanced Breast Cancer." Medical Decision Making 38, no. 7 (2018): 789–96. http://dx.doi.org/10.1177/0272989x18790966.

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Interim analyses of clinical trial data are frequently used to provide evidence to obtain marketing authorization for new drugs. However, results from such analyses may not reflect true estimates of relative effectiveness when trial follow-up is complete. Survival results, available at 2 time points from a breast cancer clinical trial, were compared to test the hypothesis that using immature data and a widely used right-censoring rule leads to biased survival estimates. Kaplan-Meier progression-free and overall survival data from 2 published CLEOPATRA trial reports (2012 and 2014) were digitiz

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Ragab, Mahmoud, Aisha Fayomi, Ali Algarni, et al. "Statistical Analysis of Joint Type-I Generalized Hybrid Censoring Data from Burr XII Lifetime Distributions." Complexity 2021 (May 21, 2021): 1–15. http://dx.doi.org/10.1155/2021/5543187.

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The quality of the products coming from different lines of production requires some tests called comparative life tests. For lines having the same facility, the lifetime of the product is distributed by Burr XII, the lifetime distribution, and units are tested under type-I generalized hybrid censoring scheme. The observed censoring data are used under maximum likelihood and the Bayes method to estimate the model parameters. The theoretical results are discussed and assessed through data analysis and Monte Carlo simulation study. Finally, we reported some brief comments obtained from numerical

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Guure, Chris B., and Samuel Bosomprah. "Bayesian Perspective on Random Censored Survival Data." International Scholarly Research Notices 2014 (October 29, 2014): 1–9. http://dx.doi.org/10.1155/2014/430357.

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A unit is said to be randomly censored when the information on time occurrence of an event is not available due to either loss to followup, withdrawal, or nonoccurrence of the outcome event before the end of the study. It is assumed in independent random/noninformative censoring that each individual has his/her own failure time T and censoring time C; however, one can only observe the random vector, say, (X;δ). The classical approach is considered for analysing the generalised exponential distribution with random or noninformative censored samples which occur most often in biological or medica

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Pretorius, Carel J., and Jacobus P. J. Ungerer. "Improved Diagnostic Performance of High-Sensitivity Cardiac Troponin Assays Is an Artifact of Censored Data." Clinical Chemistry 62, no. 12 (2016): 1654–57. http://dx.doi.org/10.1373/clinchem.2016.262634.

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Abstract BACKGROUND High-sensitivity cardiac troponin assays with improved analytical performance at low concentrations are credited with increased diagnostic sensitivity in acute coronary syndrome patients. We investigated the relationship between analytical sensitivity (detection capability) and diagnostic accuracy and tested the effect of censoring data with a software model. METHOD We generated 4 sets of results with decreasing detection capability and compared the ROC curves with and without censored data. RESULTS There was no relationship between diagnostic performance and detection capa

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Elbatal, Ibrahim, Naif Alotaibi, Salem A. Alyami, Mohammed Elgarhy, and Ahmed R. El-Saeed. "Bayesian and Non-Bayesian Estimation of the Nadaraj ah–Haghighi Distribution: Using Progressive Type-1 Censoring Scheme." Mathematics 10, no. 5 (2022): 760. http://dx.doi.org/10.3390/math10050760.

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This work will address the problem of estimating the parameters for the Nadaraj ah–Haghighi (NH) distribution using progressive Type-1 censoring (PT1C) utilizing Bayesian and non-Bayesian approaches. To apply PT1C, censoring times for each stage of censoring needed to be known before the experiment started. To solve this issue of censoring time selection, qauntiles from the NH lifetime distribution will be used as PT1C censoring time points. Maximum likelihood (ML) estimators (MLEs) and asymptotic confidence intervals (ACoIs) are produced with a focus on the censoring technique. Bayes estimate

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