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Littérature scientifique sur le sujet « DMNG-3 »

Auteur : Grafiati

Publié le 3 juin 2025

Mis à jour le 31 juillet 2025

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Articles de revues sur le sujet "DMNG-3"

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Zhang, Xin-Guo, Fei Kou, Guo-Di MA, Peng Tang, and Zhong-Duo Yang. "Pharmacokinetics and pharmacodynamics of a novel Acetylcholinesterase Inhibitor, DMNG-3." Acta Neurobiologiae Experimentalis 76, no. 2 (2016): 117–24. http://dx.doi.org/10.21307/ane-2017-011.

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Singru, Praful S., Edith Sánchez, Csaba Fekete, and Ronald M. Lechan. "Importance of Melanocortin Signaling in Refeeding-Induced Neuronal Activation and Satiety." Endocrinology 148, no. 2 (2007): 638–46. http://dx.doi.org/10.1210/en.2006-1233.

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To identify regions in the hypothalamus involved in refeeding and their regulation by α-MSH, adult rats were subjected to a 3-d fast, and 2 h after refeeding, the distribution of c-Fos-immunoreactive neurons was elucidated. Compared with fed and fasted animals, a significant increase (P &lt; 0.001) in the number of c-Fos-immunoreactive cells was identified in refed animals in the supraoptic nucleus, magnocellular and ventral parvocellular subdivisions of the hypothalamic paraventricular nucleus (PVNv), and the dorsal and ventral subdivisions of the dorsomedial nucleus (DMNd and DMNv, respe

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Bellinger, Larry L., James F. Evans, Connie M. Tillberg, and Dorothy W. Gietzen. "Effects of dorsomedial hypothalamic nuclei lesions on intake of an imbalanced amino acid diet." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 277, no. 1 (1999): R250—R262. http://dx.doi.org/10.1152/ajpregu.1999.277.1.r250.

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Within 3 h of ingesting an imbalanced amino acid diet (Imb), rats show attenuated intake, which can be ameliorated by prior administration of the serotonin receptor antagonist tropisetron (Trop). Earlier work in which the dorsomedial hypothalamic nucleus (DMN) was electrolytically lesioned (DMNL) determined that this structure plays a role in the early detection of and subsequent adaptation to Imb. However, that study did not address whether cell bodies in the DMN, fibers of passage, or both were involved in the DMNL response to Imb. In the present investigation in experiment 1, rats were give

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Eum, Jaehong, Youseong Kim, Daniel Um, Jiwoo Shin, Huisuk Yang, and Hyungil Jung. "Solvent-Free Polycaprolactone Dissolving Microneedles Generated via the Thermal Melting Method for the Sustained Release of Capsaicin." Micromachines 12, no. 2 (2021): 167. http://dx.doi.org/10.3390/mi12020167.

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(1) Background: Dissolving microneedles (DMNs), a transdermal drug delivery system, have been developed to treat various diseases in a minimally invasive, painless manner. However, the currently available DMNs are based on burst release systems due to their hydrophilic backbone polymer. Although hydrophobic biodegradable polymers have been employed on DMNs for sustained release, dissolution in an organic solvent is required for fabrication of such DMNs. (2) Method: To overcome the aforementioned limitation, novel separable polycaprolactone (PCL) DMNs (SPCL-DMNs) were developed to implant a PCL

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Yan, Chenxin, Mengzhen Xing, Suohui Zhang, and Yunhua Gao. "Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders." Polymers 15, no. 15 (2023): 3296. http://dx.doi.org/10.3390/polym15153296.

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Excessive melanin deposition in the skin leads to various skin pigmentation diseases, such as chloasma and age spots. The deposition is induced by several factors, including tyrosinase activities and ultraviolet-induced oxidative stress. Herein, we propose a multi-component, multi-pathway drug combination, with glabridin, 3-O-ethyl-L-ascorbic acid, and tranexamic acid employed as, respectively, a tyrosinase inhibitor, an antioxidant, and a melanin transmission inhibitor. Considering the poor skin permeability associated with topical application, dissolving microneedles (MNs) prepared with hyal

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Yoshinari, Tadashi, and David Shafer. "Degradation of dimethyl nitrosamine by Methylosinus trichosporium OB3b." Canadian Journal of Microbiology 36, no. 12 (1990): 834–38. http://dx.doi.org/10.1139/m90-144.

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The degradation of dimethyl nitrosoamine (DMNA) by a methanotroph, Methylosinus trichosporium OB3b, was studied using 14C-labelled DMNA. The organism was capable of assimilating DMNA-carbon and converting it to CO2. The rates of CO2 production [Formula: see text] from DMNA and its cellular uptake (VP) were linearly correlated with DMNA concentrations of 0.03–10 mM, which corresponded to approximately 3% of added DMNA metabolized in 24 h. These rates were two to three orders of magnitude less than the rate of uptake of methane [Formula: see text], [Formula: see text] was suppressed when the con

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Li, Tzu-Ling, Lih-Chu Chiou, You Shuei Lin, Jing-Ru Hsieh, and Ling-Ling Hwang. "Electrophysiological study on the effects of leptin in rat dorsal motor nucleus of the vagus." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 292, no. 6 (2007): R2136—R2143. http://dx.doi.org/10.1152/ajpregu.00563.2006.

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Immunoreactivity of leptin receptor (Ob-R) has been detected in rat dorsal motor nucleus of the vagus (DMNV). Here, we confirmed the presence of Ob-R immunoreactivity on retrograde-labeled parasympathetic preganglionic neurons in the DMNV of neonatal rats. The present study investigated the effects of leptin on DMNV neurons, including parasympathetic preganglionic neurons, by using whole cell patch-clamp recording technique in brain stem slices of neonatal rats. Leptin (30–300 nM) induced membrane depolarization and hyperpolarization, respectively, in 14 and 15 out of 80 DMNV neurons tested. B

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Jameson, Heather, Ryan Bateman, Peter Byrne, et al. "Oxytocin neuron activation prevents hypertension that occurs with chronic intermittent hypoxia/hypercapnia in rats." American Journal of Physiology-Heart and Circulatory Physiology 310, no. 11 (2016): H1549—H1557. http://dx.doi.org/10.1152/ajpheart.00808.2015.

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Hypertension is a common outcome associated with obstructive sleep apnea (OSA), a prevalent yet poorly treated cardiovascular disease. Recent studies showed oxytocin (OXT), released from hypothalamic paraventricular nucleus (PVN) neurons, activates cardiac vagal neurons in the dorsal motor nucleus of the vagus (DMNX) and may blunt cardiovascular responses to stress. This study tests whether the release of OXT from PVN fibers in the DMNX is diminished with chronic intermittent hypoxia-hypercapnia (CIH/H) exposure, an animal model of OSA, and whether activation of PVN OXT neurons restores OXT re

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ZULCAIF, ZULCAIF, NADIAH ZAFAR, ASIF MAHMOOD, and RAI MUHAMMAD SARFRAZ. "TOXICOLOGICAL EVALUATION OF NATURAL AND SYNTHETIC POLYMER BASED DISSOLVABLE MICRONEEDLE PATCHES HAVING VARIABLE RELEASE PROFILES." Cellulose Chemistry and Technology 56, no. 7-8 (2022): 777–86. http://dx.doi.org/10.35812/cellulosechemtechnol.2022.56.69.

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Acute toxicity studies of dissolvable microneedle (dMN) patches fabricated from a combination of polymers, i.e. thiolated chitosan (TCS), polyvinyl alcohol (PVA), and polyvinylpyrrolidone (PVP), were performed to determine the safety of polymers on white albino rabbits. The selected albino rabbits were categorized into four groups. Group I was a control group, whereas groups II, III and IV were administered different doses of polymeric dMN patches. The food and water uptake and the weight of the animals were observed before and after administration of the microneedle patch on days 1, 3, 5, 7 a

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Martin, K., T. H. Kong, W. Renehan, et al. "Identification and function of brain stem neurons regulating rat ileal water absorption." American Journal of Physiology-Gastrointestinal and Liver Physiology 257, no. 2 (1989): G266—G273. http://dx.doi.org/10.1152/ajpgi.1989.257.2.g266.

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The central nervous system (CNS) regions regulating ileal water and ion absorption are unknown. We determined 1) the CNS origin of brain stem neurons that directly innervate the rat ileum, and 2) that these neurons influence intestinal water absorption. Horseradish peroxidase (HRP) was injected into the muscle layer of the rat ileum. The brains were examined for HRP reaction product (HRPRP) 3, 5, or 7 days later. Only cell bodies of the dorsal motor nucleus of the vagus (DMNV) were labeled. Unilateral cervical vagotomy prevented deposition in the ipsilateral DMNV. To determine whether the DMNV

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Livres sur le sujet "DMNG-3"

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Brülhart, Luca, Flavian Negri, Naïla van Kommer, and Serge Schiltz. Geschäftsprozesse Und -Regeln: Erfolgreich Mit DMN 1. 3 und OCEB 2 Business Intermediate. Independently Published, 2021.

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Chapitres de livres sur le sujet "DMNG-3"

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"3 DMN – Überblick und Einführung." In Praxishandbuch BPMN, 7th ed. Carl Hanser Verlag GmbH & Co. KG, 2025. https://doi.org/10.3139/9783446483064.003.

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Actes de conférences sur le sujet "DMNG-3"

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Aumklad, Porawan, Phuvamin Suriyaamporn, Monrudee Sukma, Prasert Akkaramongkolporn, Nattawat Nattapulwat, and Praneet Opanasopit. "Optimization of Fluorescein Sodium-Loaded Dissolving Microneedles for Ocular Drug Delivery Using a Computational Design Strategy." In 5th International Conference and Exhibition on Pharmaceutical Sciences and Technology 2022. Trans Tech Publications Ltd, 2022. http://dx.doi.org/10.4028/p-819jt1.

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Ocular drug delivery by topical application is the most popular for the treatment of ocular diseases. However, a number of inherent anatomical and physiological ocular barriers limit the bioavailability of the drug administered by topical application. To overcome this limitation, dissolving polymeric microneedles (dMNs) have been used to create transport pathways and enhance the permeability of ocular drugs with minimal invasion. The aim of this study was to design and evaluate Optimized dMNs for ocular delivery of a hydrophilic drug using a computational design strategy. Polyvinyl alcohol/hya

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Lavrentyev, Yury, Nikolay Petrov, and Yury Nozhnitsky. "Determination of the Area of Rational Use of Hybrid Bearings With Steel Rings and Ceramic Rolling Elements in High-Speed Aircraft Engines." In ASME Turbo Expo 2021: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/gt2021-59872.

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Abstract The process of improving gas turbine engines is associated with increased thermodynamic parameters and rotor speed. In advanced aircraft engines the main rotor bearings will operate at speed index dmn &gt; 3 · 106 mm · rpm, where dm is the bearing pitch diameter (mm), and n is the rotational speed (rpm). Under these conditions, significant heat is generated in the bearings, and the use of hybrid rolling bearings with steel rings and ceramic rolling elements looks more attractive due to the ceramic’s low density and low coefficient of thermal expansion. A computational method for p

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Sacho, Isabella Batistela Inhesta, João Vitor Gerdulli Tamanini, Brunno Machado Campos, Danilo Santos Silva, Ana Carolina Coan, and Wagner Mauad Avelar. "Brain functional network alterations in patients with asymptomatic carotid disease." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.449.

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Background: The best therapeutic approach to asymptomatic carotid stenosis (ACS) is still subject to discussion. Previous studies have agreed on the findings that ACS patients present with cerebral atrophy and cognitive decline compared to healthy controls. The present study aims to identify possible alterations in the brain functional network of such patients. Objectives: Study alternations in the connectivity of the Default Mode Network (DNM) in patients with ACS of at least 70%, compared to controls. Design and Setting: A cross-sectional case-control study was carried out at the Neuroimagin

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