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1

Takamoto, Norio, Bihong Zhao, Sophia Y. Tsai, and Francesco J. DeMayo. "Identification of Indian Hedgehog as a Progesterone-Responsive Gene in the Murine Uterus." Molecular Endocrinology 16, no. 10 (2002): 2338–48. http://dx.doi.org/10.1210/me.2001-0154.

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Abstract Progesterone (P4) plays a central role in normal uterine function, from embryo implantation in endometrium to establishment and maintenance of uterine quiescence during pregnancy in the myometrium. Considering its diverse physiological effects on female reproductive function, rather little is known about downstream events of P4 action. Recent progress in differential screening technologies facilitated identification of such inducible genes. We used uteri of wild-type and progesterone receptor null mutant mice as a starting material and screened for differentially expressed genes by me
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Qian, Xun, Jennifer Mitchell, Sung-Jen Wei, Jason Williams, Robert M. Petrovich, and Stephen B. Shears. "The Ins(1,3,4)P3 5/6-kinase/Ins(3,4,5,6)P4 1-kinase is not a protein kinase." Biochemical Journal 389, no. 2 (2005): 389–95. http://dx.doi.org/10.1042/bj20050297.

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Among inositol phosphate kinases, Ins(3,4,5,6)P4 1-kinase has been considered to be an outsider with disparate sequence, a proclaimed capacity to also phosphorylate proteins and apparent 1-phosphatase activity. Such multifunctionality, coupled with ignorance of its operational domains, complicates any mechanistic rationale behind literature reports that Ins(3,4,5,6)P4 1-kinase regulates apoptosis, salt and fluid secretion, and transcription. We have expressed poly(His)-tagged human Ins(3,4,5,6)P4 1-kinase in Sf9 insect cells and purified the enzyme using Ni–agarose chromatography. Protein kina
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Morgensztern, D., S. N. Waqar, F. Gao, and R. Govindan. "Improving survival for metastatic non-small cell lung cancer: A SEER database analysis from 1990 to 2005." Journal of Clinical Oncology 27, no. 15_suppl (2009): 8078. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.8078.

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8078 Background: Treatment of metastatic non-small cell lung cancer (NSCLC) has evolved over the last decade with the increased use of third-generation chemotherapy agents, established benefits from second-line chemotherapy, and the development of targeted agents. We conducted a study to evaluate whether these treatment advances translated into improved survival in a large registry database. Methods: The Surveillance Epidemiology and End Results (SEER) registry was queried for patients with NSCLC stage IV, aged 21 or older, and diagnosed between 1990 and 2005. Overall Survival (OS) rates were
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Matsuda, H., Y. Hashiyada, T. Yamanouchi, and K. Imai. "75 DETECTION OF EMBRYONIC DEATH BY MONITORING OVARIAN STEROIDS BALANCE AND ULTRASONOGRAPHY IN JAPANESE BLACK CATTLE." Reproduction, Fertility and Development 26, no. 1 (2014): 151. http://dx.doi.org/10.1071/rdv26n1ab75.

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In beef cattle, 20 to 44% embryonic loss occurs during the early stages of pregnancy (Humblot et al. 2001). However, the mechanism of early and late embryonic death is not clear. We investigated occurrence of embryonic death by monitoring ovarian hormones dynamics and checking for the presence of the conceptus after artificial insemination or embryo transfer in beef cattle. Twenty Japanese black females were inseminated (AI) and 12 females were transferred with 1 embryo (ET). Blood samples were collected on Days 21, 24, 28, 38, 48, 58, and 68 post-oestrus (oestrus = Day 0) and then stored at –
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Moura, G. S., V. A. Nascimento, F. A. Oliveira, A. R. Dias, M. Dias, and C. A. A. Torres. "31 PREGNANCY RATE OF CROSSBRED COWS SUBMITTED TO FIXED-TIME AI AND ADMINISTRATION OF GONADOTROPIN-RELEASING HORMONE ANALOGUE TWELVE DAYS AFTER AI." Reproduction, Fertility and Development 22, no. 1 (2010): 173. http://dx.doi.org/10.1071/rdv22n1ab31.

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The importance of serum progesterone (P4) during the first weeks of pregnancy to reduce the embryo mortality in cattle herds has been demonstrated (Mann and Lamming 2001 Reproduction 121, 175-180). Studies show that a P4 peak at the beginning of pregnancy (about 5 days after the natural breeding or AI) helps development of the concept via secretion of interferon-τ (Mann 2002 XXII World Buiatrics Congress 18-23, 300-306). Studies have shown that the administration of gonadotropin-releasing hormone (GnRH) or its agonists after AI may stimulate corpus luteum function, induce the formation of an a
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Pohlkamp, Marc W., and Wolfgang Jeitschko. "Preparation, Properties, and Crystal Structure of Quaternary Silicide Carbides RCr2Si2C (R = Y, La - Nd, Sm, Gd - Ho)." Zeitschrift für Naturforschung B 56, no. 11 (2001): 1143–48. http://dx.doi.org/10.1515/znb-2001-1108.

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The title compounds were prepared by arc-melting cold-pressed pellets of the elemental components. They crystallize with a tetragonal structure already reported for CeCr2Si2C. It was refined from single-crystal X-ray data of PrCr2S2C: P4/mmm, a - 402.2( 1) pm, c = 535.2(1) pm, Z = 1, R = 0.012 for 252 structure factors and 10 variable parameters. Magnetic susceptibility measurements with a SQUID magnetometer indicate Pauli paramagnetism for YCr2Si2C, while CeC2Si2C shows mixed valent behavior. The carbon atoms in the structure of these compounds are isolated from each other. The silicon atoms
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Stadler, Florian, Thomas Fickenscher, and Rainer Pöttgen. "Synthesis and Structure of RE2Rh2Cd (RE = La, Ce, Pr, Nd, Sm)." Zeitschrift für Naturforschung B 56, no. 11 (2001): 1241–44. http://dx.doi.org/10.1515/znb-2001-1122.

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New intermetallic cadmium compounds RE2Rh2Cd (RE= La, Ce, Pr, Nd, Sm) were synthesized from the elements in sealed tantalum tubes in a high-frequency furnace. They were characterized through X-ray powder data: Mo2FeB2 type, space group P4/mbm, Z = 2. Single crystal data of the cerium compound (a = 762.8(1), c = 377.8(1) pm, wR2 = 0.0662, 199 F2 values, and 13 variable parameters) revealed small defects on the rhodium position leading to the composition Ce2Rh186(3)Cd for the investigated crystal. According to the course of the cell volumes Ce2Rh2Cd may be classified as a mixedvalent compound. T
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London, W. B., R. P. Castleberry, K. K. Matthay, et al. "Evidence for an Age Cutoff Greater Than 365 Days for Neuroblastoma Risk Group Stratification in the Children's Oncology Group." Journal of Clinical Oncology 23, no. 27 (2005): 6459–65. http://dx.doi.org/10.1200/jco.2005.05.571.

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Purpose In the Children's Oncology Group, risk group assignment for neuroblastoma is critical for therapeutic decisions, and patients are stratified by International Neuroblastoma Staging System stage, MYCN status, ploidy, Shimada histopathology, and diagnosis age. Age less than 365 days has been associated with favorable outcome, but recent studies suggest that older age cutoff may improve prognostic precision. Methods To identify the optimal age cutoff, we retrospectively analyzed data from the Pediatric Oncology Group biology study 9047 and Children's Cancer Group studies 321p1-p4, 3881, 38
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GEORGE, KAI HORST, and CHRISTOPH PLUM. "Description of two new species of Dorsiceratus Drzycimski, 1967 (Copepoda: Harpacticoida: Ancorabolidae) from Sedlo and Seine Seamounts (Northeastern Atlantic) and remarks on the phylogenetic status of the genus." Zootaxa 2096, no. 1 (2009): 257–86. http://dx.doi.org/10.11646/zootaxa.2096.1.15.

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Two new species of Dorsiceratus Drzycimski, 1967 (Copepoda, Harpacticoida, Ancorabolidae), Dorsiceratus wilhelminae sp. nov. and D. dinah sp. nov. are described from Sedlo and Seine Seamounts, respectively (both northeast Atlantic). These are the first records of Dorsiceratus species from seamount summits. Both new species resemble the described species D. octocornis Drzycimski, 1967, D. triarticulatus Coull, 1973, and D. ursulae George, 2006, with respect to most morphological features. On the other hand, D. wilhelminae sp. nov. has long spinules at the inner margin of the A2 enp, while D. di
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10

Wakako, Tajiri. "Abstract P4-05-11: The clinical importance of the new category, ER low-positive in the ER expression HER2 negative early breast cancer." Cancer Research 82, no. 4_Supplement (2022): P4–05–11—P4–05–11. http://dx.doi.org/10.1158/1538-7445.sabcs21-p4-05-11.

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Abstract <Background>In the latest updated ASCO/CAP guideline, a new category, ER low-positive was introduced, which are determined by the 1% to10 % of positive staining of the tumor nuclei for ER. However clinical meaning of ER-low positive was unclear compared with ER- positive or ER-negative in HER2 negative breast cancer. <Purpose> In order to clarify the clinicopathological features of ER-low positive breast cancer, we compared the clinicopathological factors and prognosis among three groups, ER negative, ER-low positive, and ER-positive groups in the patients
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Garay-Serrano, E., S. P. Fernández-Pavía, G. Rodríguez-Alvarado, et al. "First Report of Haplotype I-b of Phytophthora infestans in Central Mexico." Plant Disease 91, no. 7 (2007): 909. http://dx.doi.org/10.1094/pdis-91-7-0909b.

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Central Mexico is considered a center of genetic diversity for Phytophthora infestans on the basis of a range of genotypic and phenotypic characteristics (3). Surprisingly, while mitochondrial DNA (mtDNA) haplotypes I-a, II-a, and II-b have been reported from central Mexico, haplotype I-b has not been found in central Mexico (1). Therefore, a more extensive search for haplotypes was conducted in areas where sexual reproduction occurs. During the summer of 2003, leaflets of cvs. Rosita and Tollocan with a single lesion of late blight were collected in the area of Villarreal, located in Terrenat
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Garcia-Torralba, Esmeralda, Beatriz Álvarez-Abril, Carlos Bravo-Pérez, et al. "Abstract P4-07-03: Development of prognostic models based on clinical, immune-related and proliferation factors in early breast cancer patients treated with neoadjuvant chemotherapy." Cancer Research 82, no. 4_Supplement (2022): P4–07–03—P4–07–03. http://dx.doi.org/10.1158/1538-7445.sabcs21-p4-07-03.

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Abstract Introduction and objectives Up to 30% of early breast cancer (BC) patients treated with neoadjuvant chemotherapy will have systemic relapse during the follow-up. The integration of clinical, analytical and molecular parameters associated to tumor biology or host immune response could help to better stratify the prognosis of these patients. The aim of this study was to analyze the prognostic ability of immune-related and proliferation markers in combination with clinical parameters in patients with early BC treated with neoadjuvant chemotherapy. Methods and materials Retrospective and
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Viau, P., M. B. Paes de Barros, L. M. K. Dias, S. S. Nicolau, C. T. Marino, and C. A. Oliveira. "174 EVALUATION OF THE 9-DAY PROTOCOL FOR ESTROUS SYNCHRONIZATION IN SANTA INÊS EWES." Reproduction, Fertility and Development 23, no. 1 (2011): 189. http://dx.doi.org/10.1071/rdv23n1ab174.

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The objective of the present study was to characterise follicular dynamics in Santa Ines (SI) during a 9-day protocol for oestrous synchronization and to evaluate the efficiency of the vaginal progesterone-releasing device Primer-PR® (Tecnopec, Brazil). Cyclic females were used (n = 10) at the ruminant sector of the veterinary hospital of the FMVZ–USP, in March 2009. The animals had body scores between 2.5 and 3 and were of proven fertility. Ultrasound examinations were performed using an ALOKA SSD-500 Scanner (Berger, Brazil) with a linear 5.0-MHz transducer, attached to a handle to allow saf
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Merlo, B., E. Iacono, F. Prati, and G. Mari. "319IN VITRO MATURATION OF EQUINE OOCYTES IN A COMPLETELY DEFINED MEDIUM SUPPLEMENTED WITH PROGESTERONE." Reproduction, Fertility and Development 16, no. 2 (2004): 279. http://dx.doi.org/10.1071/rdv16n1ab319.

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A completely defined medium for in vitro maturation (IVM) of equine oocytes has not yet been developed, since most of the media used for IVM are supplemented with serum or BSA. Furthermore, in this species there is no report about the influence of progesterone on maturation, although it has already been used as supplement (500ngmL−1) in EMMI (Maclellan LJ et al., 2001, Theriogenolgy 55, 310 abst). The aims of this study were to develop a completely defined medium for equine oocyte maturation and to investigate the effect of progesterone on nuclear maturation. Equine oocytes were collected by f
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Miragaya, M., M. Revora, F. Rigali, et al. "50 FIRST EQUINE CLONE BORN IN ARGENTINA BY SOMATIC CELL NUCLEAR TRANSFER FROM A POLO ARGENTINO MARE." Reproduction, Fertility and Development 23, no. 1 (2011): 131. http://dx.doi.org/10.1071/rdv23n1ab50.

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Births of the first cloned equids were reported in 2003 (Woods et al. 2003 Science 301(5636), 1063; Galli et al. 2003 Nature 424 (6949), 635) but no equine clones have been reported in Latin America. The aim of this work was to inform the birth of the first equine clone in Argentina as a result of interdisciplinary teamwork. Equine oocytes were obtained from slaughterhouse ovaries and were transported at 38°C for 15 h in TCM-199 buffered with 20 mM HEPES and supplemented with 1 mM glutamine, 0.19 mM sodium pyruvate, 2 μg mL–1 LH, 5 μg mL–1 FSH, 100 ng mL–1 EGF, 100 ng mL–1 IGF-I, and 10% FCS.
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16

Garcia-Torralba, Esmeralda, Beatriz Álvarez-Abril, Carlos Bravo-Pérez, et al. "Abstract P4-07-11: Prognostic significance of changes in tumor infiltrating lymphocytes and neutrophil-to-lymphocyte ratio after neoadjuvant chemotherapy in early breast cancer patients." Cancer Research 82, no. 4_Supplement (2022): P4–07–11—P4–07–11. http://dx.doi.org/10.1158/1538-7445.sabcs21-p4-07-11.

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Abstract Introduction. There are still 30-40% of patients with early breast cancer (BC) that relapse after neoadjuvant chemotherapy (NAC). New prognostic biomarkers are needed. Current evidence shows that both markers of antitumor local and systemic immune response, such as tumor infiltrating lymphocytes (TIL) and neutrophil-to-lymphocyte ratio (NLR) have prognostic value in early BC. Most works have evaluated baseline levels, but their variation after NAC might be related to treatment resistance and should be explored.The aim of this study was to simultaneously investigate the prognostic sign
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Heredia, Ana, Benjamin Walbaum, Francisco Acevedo, and Cesar Sánchez. "Abstract P4-07-05: Real world data of adjuvant endocrine therapy for breast cancer in very young women. A Chilean 20-year experience." Cancer Research 83, no. 5_Supplement (2023): P4–07–05—P4–07–05. http://dx.doi.org/10.1158/1538-7445.sabcs22-p4-07-05.

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Abstract BACKGROUND: Breast cancer (BC) is the most common cancer diagnosed in premenopausal women with an increasing incidence for age 35 or less. Although proportionally less frequent, hormone receptor (HR)–positive BC still remains the main subtype for this group, but given tumor characteristics and suboptimal adjuvant endocrine therapy (ET), present inferior long-term outcomes when compared to HR-positive BC in older women. Both Tamoxifen and Exemestane Trial (TEXT) and Suppression of Ovarian Function Trial (SOFT) have helped to optimize ET strategies for premenopausal women, identifying w
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Olivier, C. Y., G. Séguin-Swartz, D. Hegedus, and T. Barasubiye. "First Report of “Candidatus Phytoplasma asteris”-Related Strains in Brassica rapa in Saskatchewan, Canada." Plant Disease 90, no. 6 (2006): 832. http://dx.doi.org/10.1094/pd-90-0832c.

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“Candidatus phytoplasma asteris” and related strains (i.e., aster yellows group 16SrI) have been associated with diseases of numerous plant species worldwide. Symptoms of aster yellows (AY) have been reported on rapeseed/canola (Brassica napus and B. rapa) crops in Saskatchewan (SK) and Manitoba, Canada since 1953 (2). Symptoms generally include stunting, virescence, leaf yellowing or purpling, phyllody, and formation of bladder-like siliques. A total of 120 mature B. rapa cv. AC Sunbeam plants exhibiting AY symptoms were collected in commercial fields near Medstead, SK during 2003 and 2004 (o
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El, Morsy A.A., H.M.H. Tammam, and M.A.S. Moharram. "Effect of different modes of ventilation on diaphragmatic excursion in mechanically ventilated patients: ultrasonographic assessment." Biolife 3, no. 4 (2022): 905–9. https://doi.org/10.5281/zenodo.7309370.

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<strong>ABSTRACT</strong> <strong>Objective:</strong> Ultrasonographic assessment of the effect of different modes of mechanical ventilation on diaphragmatic excursion and consequently its effect on weaning of mechanical ventilation, total ventilatory days, hospital stay and mortality. <strong>Patients and methods:</strong> This study was carried out on 61 mechanically ventilated adult patients of both genders who were admitted to Critical Care Medicine Department in Alexandria main university hospital over a period from 1/6/2014 to 30\11\2014. All patients were subjected to complete medical a
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El, Morsy A.A, M.R Ibrahim, and M.M.A Sakr. "Serial ultrasonographic evaluation of diaphragm thickness during mechanical ventilation in ICU patients." Biolife 3, no. 4 (2022): 922–36. https://doi.org/10.5281/zenodo.7309376.

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<strong>ABSTRACT</strong> <strong>Objective:</strong> Serial ultrasonographic assessment of the effect of different modes of mechanical ventila-tion on diaphragmatic thickness and consequently its effect on weaning of mechanical ventilation, total ventilatory days, ICU stay and mortality. <strong>Patients and methods:</strong> This study was carried out on 67 mechanically ventilated adult patients of both genders who were admitted to Critical Care Medicine Department in Alexandria main university hospital over a period from 1/4/2014 to 30\9\2014. All patients were subjected to complete medical
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Obatusin, Mosadoluwa O., Levy A. Reyes, Jorge M. Serrador, and Glenn D. Wylie. "fMRI‐based method to describe human brain size as a function of age and height." FASEB Journal 30, S1 (2016). http://dx.doi.org/10.1096/fasebj.30.1_supplement.749.6.

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Brain size may not matter, but proportions sure do. Haller's Rule, which holds that brains of smaller animals must take up more room to function, has been a landmark principle for all who have considered brain size. Since, the brain is part of the body, it is important to know the relationships of brain size to body size. To date, there has not been a method that assesses brain size using functional magnetic resonance imaging (fMRI). all other methods described in literature are based on autopsy and MRI [Filipek et al. (1994), Caviness et al. (1996), Courchesne et al. (2000), Dekaban and Sadow
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O'Rourke, Polly, and Gregory Colflesh. "P600 Dominance Predicts Comprehension of Garden-Path Sentences." LSA Annual Meeting Extended Abstracts, April 13, 2015. http://dx.doi.org/10.3765/exabs.v0i0.3008.

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&lt;h1 align="left"&gt;&lt;span style="font-family: Times New Roman;"&gt;&lt;span style="font-size: medium;"&gt;1. Introduction.&lt;/span&gt;&lt;span style="font-size: medium;"&gt; &lt;/span&gt;&lt;span style="font-size: medium;"&gt;Research using the event-related potential (ERP) technique has provided many important insights into the neural mechanisms associated with language comprehension. The integration of lexico-semantic information is associated with an increased centro-parietal negativity between 300-500 ms known as the N400 (Kutas &amp;amp; Federmeier, 2011; Kutas &amp;amp; Hillyard 1
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Henry, Hill. "B9   源頭立法和生死數學:無限田忌賽馬和國格侵犯摧毀美國". 3 листопада 2022. https://doi.org/10.5281/zenodo.7276331.

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B9 &nbsp; 源頭立法和生死數學:無限田忌賽馬和國格侵犯摧毀美國 Source Legislation and Life-and-death Mathematics to Great Divide:Nationality Infringe to Destroy USA 阿紫宝宝(Henry Hill) This is Source Legislation and Life-and-death Mathematics to Great Divide: Nationality Infringe to Destroy USA. I am the highest thermonuke expert in the world to prevent the nuclear war to doomsday. Please all ones help me come to USA to start the Anti-Manhattan Grating Project, for the people, by the world and of the USA, because it is only USA can provide the support. 宇宙很大很大,但也有很小很小的时候:在宇宙万物之源的范数层面也很小很小,如同孙悟空在如来佛手掌心中一样道理。还有,在美国和联合国原子能安全机构
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Henry, Hill. "Source Legislation and Life-and-death Mathematics to Great Divide:Nationality Infringe to Destroy USA." November 3, 2022. https://doi.org/10.5281/zenodo.7276354.

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B9 &nbsp; 源頭立法和生死數學:無限田忌賽馬和國格侵犯摧毀美國 Source Legislation and Life-and-death Mathematics to Great Divide:Nationality Infringe to Destroy USA 阿紫宝宝(Henry Hill) This is Source Legislation and Life-and-death Mathematics to Great Divide: Nationality Infringe to Destroy USA. I am the highest thermonuke expert in the world to prevent the nuclear war to doomsday. Please all ones help me come to USA to start the Anti-Manhattan Grating Project, for the people, by the world and of the USA, because it is only USA can provide the support. 宇宙很大很大,但也有很小很小的时候:在宇宙万物之源的范数层面也很小很小,如同孙悟空在如来佛手掌心中一样道理。还有,在美国和联合国原子能安全机构
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