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1

DeSoto, Mary Catherine. "Symptoms of borderline personality disorder and levels of estrogen /." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3025615.

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Lang, Claudia Nicole. "Investigation of the Effects of Xenoestrogens on the Protein Levels of the Estrogen Receptors." Thesis, University of Canterbury. Biological Sciences, 2006. http://hdl.handle.net/10092/1470.

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There has been an increase in reports of male reproductive disorders that include male infertility and testicular cancer worldwide. It has been suggested that agents such as xenoestrogens could be responsible. Xenoestrogens are chemical compounds that mimic the action of estrogens by binding to the estrogen receptors (ERs). The response ofa testicular cell line to estrogenic pesticides was examined. The effect of estrogenic pesticides on the growth and protein levels of ERα and ERβ of mouse Sertoli cells was investigated. Pyrethroids are widely used insecticides due to their insecticidal
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3

Romano, Nicola, and n/a. "Rapid effects of estrogen on intracellular calcium levels in adult GnRH neurons." University of Otago. Department of Physiology, 2009. http://adt.otago.ac.nz./public/adt-NZDU20090310.144345.

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The gonadotropin-releasing hormone (GnRH) neurons of the hypothalamus are the principal regulators of reproductive function and are strongly modulated by estrogen (E₂). Several studies indicate that E₂ is able to influence GnRH neurons, both with "classical" long-term transcriptional effects, and with rapid non-transcriptional effects. One most interesting action of E₂ is that of modulating intracellular calcium concentration [Ca�⁺]I: this has been shown to happen in many different cell types, including embryonic models of GnRH neurons. The aim of this project was to evaluate if these rapid
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Larsen, Cody David. "Proteomic characterization of testicular protein expression in male hornyhead turbot exhibiting high plasma estrogen levels." Thesis, California State University, Long Beach, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=1569889.

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<p> In selected locations offshore of urban southern California, male hornyhead turbot <i>(Pleuronichthys verticalis)</i> exhibit elevated plasma concentrations of the female sex steroid, 17&beta;-estradiol (E2). Males sampled from Santa Monica Bay have consistently elevated E2 concentration (>1000 pg/ml), as much as 10 times higher than males from locations offshore of Orange County. Since estrogens, including E2, are at undetectable levels in the ocean discharge of regional WWTPs, it was of interest to determine whether testicular expression of steroidogenic enzymes and other proteins impact
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5

Phillips, Susana M. (Susana Maria). "The relationship between sex steroid levels and memory functions in women." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=28513.

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Memory function was examined in association with sex hormone levels in women. The results of the first study suggest that self-reports of memory problems were especially prevalent among women attending a menopause clinic compared to a nonpatient sample. In the following investigation, women given placebo after undergoing a bilateral oophorectomy showed decreases in memory performance, specifically on a paired-associate learning task, coincident with declines in estrogen levels. Significant improvements were found in estrogen-treated women pre- to postoperatively in the immediate recall of para
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McLaren, Julie. "Quantification of mRNA levels for LH-beta, FSH-beta, alpha and prolactin in female rats following chronic or acute estrogen treatment." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=68220.

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Injection of 2mg of estradiol valerate (EV) to cycling female rats causes cell death among the hypothalamic beta-endorphin population that results in increased mu-opioid receptor binding in the hypothalamic MPOA. We suspect that the subsequent opioid suppression of the GnRH system is responsible for the constellation of defects that occur in pituitary LH production and release.<br>In order to determine the mechanisms by which a defective GnRH pattern affects pituitary LH functions, we quantitated LH-beta and alpha mRNA in EV-injected animals using Northern blot analysis. To determine whether e
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7

Pettersson, Hanna. "Steroid-Metabolizing Cytochrome P450 (CYP) Enzymes in the Maintenance of Cholesterol and Sex Hormone Levels." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-100787.

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Diss. (sammanfattning) Uppsala : Uppsala universitet, 2009.<br>Disputationsordförande;Professor Eva Brittebo, Inst. för Biovetenskap, Avd. för Toxikologi, Uppsala Universitet, UppsalaBetygsnämndens ledamöten; Docent Lena Ekström, Inst. för Laboratoriemedicin, Avd. för Klinisk Kemi, Karolinska Universitetssjukhuset, HuddingeDocent Ulf Diczfaluzy, Inst. för Laboratoriemedicin, Avd. för Klinisk Kemi, Karolinska Universitetssjukhuset, HuddingeProfessor Agneta Oskarsson, Inst. BVF, Avd. för farmakologi och toxikologi, SLU, Uppsala. Härtill 4 uppsatser.
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8

SILVA, Sandra Maria Souza da. "Efeito de xenoestrógeno associado à melatonina sobre o aparelho reprodutor de ratas adultas." Universidade Federal Rural de Pernambuco, 2013. http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/4663.

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Submitted by (lucia.rodrigues@ufrpe.br) on 2016-06-09T14:56:06Z No. of bitstreams: 1 Sandra Maria Souza da Silva.pdf: 1116227 bytes, checksum: 547243820615bfc6e7266bb8181631ec (MD5)<br>Made available in DSpace on 2016-06-09T14:56:07Z (GMT). No. of bitstreams: 1 Sandra Maria Souza da Silva.pdf: 1116227 bytes, checksum: 547243820615bfc6e7266bb8181631ec (MD5) Previous issue date: 2013-02-14<br>Cimetidine, a H2 receptor blocker parietal cell acts as xenoestrogênica substance. Chronic use produces hormonal disorders and toxicity in the male reproductive system in addition to reducing the 2-
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9

Seo, Hye-Sook. "Regulation of the level of estrogen receptor and its assiociated transcriptional activity under estrogenic and antiestrogenic stimulation in MCF-7 breast cancer cells." Doctoral thesis, Universite Libre de Bruxelles, 2002. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/211431.

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10

Bennett-Wimbush, Karen. "The effects of altered prolactin levels on follicular dynamics and endocrine profiles in transitional pony mares /." free to MU campus, to others for purchase, 1996. http://wwwlib.umi.com/cr/mo/fullcit?p9712793.

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11

Jijana, Abongile Nwabisa. "Development of electrochemical ZnSe Quantam dots biosensors for low-level detection of 17β-Estradiol estrogenic endocrine disrupting compound". Thesis, University of the Western Cape, 2010. http://hdl.handle.net/11394/2310.

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Magister Scientiae - MSc<br>The main thesis hub was on development of two electrochemical biosensors for the determination of 17β-estradiol-estradiol: an estrogenic endocrine disrupting compound. Endocronology have significantly shown that the endocrine disruptors contribute tremendously to health problems encountered by living species today, problems such as breast cancer, reproductive abnormalities, a decline in male population most significant to aquatic vertebrates, reduced fertility and other infinite abnormalities recurring in the reproductive system of mostly male species. The first bio
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12

Van, Zijl Catherina. "Estrogenic activity target endocrine disrupting chemical levels and potential health risks of bottled water and water from selected distribution points in Pretoria and Cape Town." Thesis, University of Pretoria, 2016. http://hdl.handle.net/2263/61675.

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Endocrine disrupting chemicals (EDCs) are ubiquitous in the environment and have been detected in drinking water. Although various water treatment processes can remove EDCs, chemicals can migrate from pipes that transport water and contaminate drinking water. Globally bottled water consumption is steadily rising as an alternative to tap water, but EDCs have also been detected in bottled water. Sources of EDCs in bottled water include contamination of the water source, contamination through the production process or the migration of EDCs from the packaging material. There is limited info
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13

Huang, Zi-Qiang, and 黃自強. "Relationship between deciduomal development and estrogen, progesterone receptor levels in the pregnant hamster." Thesis, 1986. http://ndltd.ncl.edu.tw/handle/41102163931775510409.

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14

Yang, Deng-Ho, and 楊登和. "Levels of circulating advanced glycation end-products, osteopontin and estrogen in menopausal women with osteoporosis." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/24940010148302161150.

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博士<br>中山醫學大學<br>醫學研究所<br>102<br>Advanced glycation end-products (AGEs) can accumulate in organs and tissues during ageing and diabetes. Increased levels of serum AGEs are found in the bone tissue of patients with osteoporosis. The purpose of this study was to evaluate circulating AGEs in patients with osteoporosis. We evaluated plasma AGEs, osteoporosis-related biomarkers, and bone mass in 82 menopausal women with osteoporosis or osteopenia, 16 young women with osteopenia, and 43 healthy women without osteoporosis or osteopenia. Higher levels of serum AGEs were found in the osteoporosis or ost
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15

West, Sarah. "The effects of estrogen deficiency and energy deficiency on osteoprotegerin and RANKL levels in exercising premenopausal women." 2007. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=788725&T=F.

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16

Wen, Jie. "Decreased BRCA1 levels confer Tamoxifen resistance in breast cancer cells /." 2008. http://wwwlib.umi.com/dissertations/fullcit/3322509.

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Guo, Jimin. "The effect of SRA intron-1 splicing on differential ratio of SRA-SRAP levels and on ER-mediated transcription in breast cancer cells." 2008. http://hdl.handle.net/1993/3097.

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The steroid receptor RNA activator gene (SRA1) generates two distinct entities. SRA RNA coactivates several NRs whereas SRA protein (SRAP) is suspected to regulate the activity of several transcription factors, including estrogen receptors (ER). Splicing of SRA intron-1 is the major event defining SRAP coding frame. Fully spliced, coding SRA and intron-1 retained, non-coding SRA coexist in breast cancer cells. The relative proportion between the two types of SRA RNA maintains a balance between two genetically linked entities, SRA and SRAP. In this study, a minigene model was used to dem
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18

Fang, Wei-An, and 方偉安. "Investigation of the associations of background levels of estrogen quinone-derived protein adducts and genetic polymorphisms with risk of developing breast cancer in Taiwanese women." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/88889132452011061138.

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碩士<br>國立中興大學<br>環境工程學系所<br>102<br>The aims of this studywere to investigate the associations of the genetic polymorphisms with the background level of estrogen, including estrone (E1) and 17β-estradiol(E2), quinone-derived protein adducts and the risk of developing breast cancer in Taiwanese women and to develope a method to simultaneously analyze both E1 and E2 quinone-derived adducts in human albumin and hemoglobin. Rssults from analysis of single nucleotide polymorphisms indicated that the frequencies of variant allels of estrogen metaboism gene CYP1A1 T3801C were estimated to be 31.0% and
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Chu, Shu-Cheng, and 朱書呈. "Investigation of the Associations of the Background Levels of Estrogen Quinone-Derived Protein Adducts with Dioxin Exposure and Catechol-O-Methyl Transferase (COMT) Genetic Polymorphisms." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/34405810835958169468.

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碩士<br>國立中興大學<br>環境工程學系所<br>103<br>The objective of the first part of this study was to investigate the effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure on the formation of estrogen quinone-derived cytoplasmic protein (Cp) adducts, including estrogen-2,3-quinones (E2-2,3-Q) and estrogen-3,4-quinones (E2-3,4-Q) , in human lung adenocarcinoma cell line CL1-5 (TO), including CL1-5 (TO-AhR) , CL1-5 (TO- AhR/ERα), and CL1-5 (TO-ERα). Results indicated that the background level of E2-3,4-Q-2-S-Cp was significantly increased in CL1-5 (TO-AhR/ERα) and CL1-5 (TO-ERα) cells treated with TC
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20

Chen, Cheng-You, and 陳政佑. "Investigation of the Associations of Genetic Polymorphisms in Estrogen Metabolism and DNA Repair with the Background Levels of Abasic Sites and Risk of Developing Breast Cancer." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/46852814112567541167.

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碩士<br>國立中興大學<br>環境工程學系所<br>101<br>The objectives of this research were to investigate the associations of the risk factors of breast cancer, including body mass index (BMI, Kg/m2) , age, and polymorphisms of genes involved in DNA repair and estrogen metabolism with the background levels of abasic sites (AP sites) in Taiwanese women with breast cancer and controls. Results indicated that the background levels of AP sites (mean ± SD) in healthy controls (n=140) were estimated to be 23.3 ± 13.5 per 106 nucleotides. There is a 2.2-fold increase in the background levels of AP sites when compared
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21

Liu, Chin-Chen, and 劉致辰. "Investigation of the association of body mass index and polymorphisms of genes responsible for estrogen bioactivation with the background levels of abasic sites in white blood cells derived from breast cancer patients." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/07331406563519587585.

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碩士<br>國立中興大學<br>環境工程學系所<br>99<br>Breast cancer is one of the most prevalent cancer among women in Taiwan. Epidemiological studies suggest that cumulative estrogen dose is a key determinant of breast cancer risks. Laboratory research provides evidence that estrogen quinone-derived direct and oxidative DNA (deoxyribonucleic acid) damage and the subsequent formation of abasic sites (AP sites) play an important role in the initiation of estrogen carcinogenesis. The objective of this research was to investigate association of the risk factors of breast cancer, including age, body mass index (BMI)
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Chen, Chin-Hsun, and 陳晉勳. "Response of serum leptin level in rats after ovariectomy and Estrogen supplement." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/33319898676932959163.

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碩士<br>中山醫學院<br>生物化學研究所<br>88<br>This experiment is aimed at discussing the mechanism of gaining weight of women between “ Postmenopausal ײ from “ Primenopausal ײ During the research, using “ Ovariectomy — induced obesity model ײ to observing how leptin plays a role during the procedure. During a 17-week-long experiment, we observed the variation and influence of the leptin when the “ Estrogen ײ is loses and “ Estrogen ײ gain of in rats. According to the results, the weight gaining on the OVX group, which “Ovariectomy-induced obesity model ײ was applied, was far ahead than the other
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23

He, Xiang-Cheng, and 何項成. "The effects of estrogen, trivalent chromium and combination of estrogen and trivalent chromium on the level of vasopressin in serum of ovariohysterectomized rats." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/62423481996902856231.

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碩士<br>國立中興大學<br>獸醫學系暨研究所<br>105<br>The neurohypophysial hormone vasopressin (VP), also known as an antidiuretic hormone, is involved in a wide range of physiological regulatory processes, including renal water reabsorption, cardiovascular homeostasis, hormone secretion from the anterior pituitary. Target organs and cells perceive hormonal stimuli by vasopressin (VP) through three distinct VP receptors, V1a, V1b, and V2. The V2 receptor is located in the renal distal tubules and collecting ducts, and stimulates water absorption. V1a receptor plays a role in maintaining urine flow for renal func
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CHEN, JEN-JUI, and 陳人睿. "Effect of Estrogen on Brain Docosahexaenoic Acid Level and Spatial Learning Memory Performance." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/16509839339394353418.

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碩士<br>國立臺灣大學<br>生理學研究所<br>95<br>Background: Postmenopausal women who take estrogen therapy have higher plasma DHA level and women have higher DHA level in plasma than men, indicating estrogen may play an important role for DHA accumulation in tissues. Aim: The study is to determine whether estrogen deprivation could decrease DHA deposition in brain regions and peripheral tissues. Material and method: DHA deficient rats were created by feeding DHA deficient diet for one generation. The DHA deficient rats (F2) and the chow diet feeding animal (F1) were ovariectomized (OVX) or sham operatio
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Yi-ChenLiu and 劉奕辰. "Peptide-Level Affinity Enrichment for the Identification of Nuclear Protein Targets of Catechol Estrogens." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/9gpgr9.

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碩士<br>國立成功大學<br>化學系<br>106<br>Catechol estrogens (CEs) are known to react with DNA and form adducts that are believed to be the initiators of estrogen-induced tumorigenesis. CEs covalently interaction with cellular proteins, referred as estrogenized proteins, influencing molecular function. Their conjugation sites are Cysteine, Lysine and Histidine. There is no feasible method to identify their binders in a living system. Here, we developed a click chemistry-based affinity enrichment to identify protein targets of CEs using liquid chromatography-mass spectrometry (LC-MS). Human insulin was est
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26

Tsai, Jin-Wei, and 蔡進偉. "Levels of estrogenic chemicals in drinking water in Taiwan and their removal during the treatment processes." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/34597625642149230844.

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碩士<br>國立臺灣大學<br>環境衛生研究所<br>97<br>There is a concern on the removal of ferminizing chemicals during the drinking water treatment processes. This study investigated the removal of seven estrogenic chemicals during the drinking-water-treatment (DWT) processes from seven plants in Taiwan between July 2007 and May 2008 using solid phase extraction (SPE) and ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The analytes were estrone (E1), 17β-estradiol (E2), estriol (E3), 17α-ethynylestradiol (EE2), bisphenol-A (BPA), 4-tert-octylphenol (OP) and 4-nonylphenol (NP). We fo
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Muirhead, Elisabeth Knowles. "Polybrominated diphenyl ethers: levels in Townsville sediments, depuration and (anti-)estrogenic effects in Barramundi (Lates calcarifer)." Thesis, 2008. https://researchonline.jcu.edu.au/4778/1/Thesis_front.pdf.

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The purpose of this research was to study polybrominated diphenyl ethers (PBDEs) and the effect they have in North Queensland, Australia, specifically in reference to a commercially important fish species, barramundi (Lates calcarifer). This thesis is separated into four main sections: determination of PBDE levels in Ross Creek, Townsville, QLD; toxicokinetics of PBDE-47 in barramundi; optimization of an enzyme-linked immunosorbent assay (ELISA) for detection of vitellogenin (Vtg) in barramundi; and assessing the (anti-)estrogenic effect of PBDE-47 in barramundi. Levels of two common PBDE c
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Yu-MinLin and 林育民. "Relative quantification of the conjugation level of catechol estrogen in circulating blood with hemoglobin by LC-MS/MS using parallel reaction monitoring." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/953ven.

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Yu-ShanHuang and 黃郁珊. "Relative quantification of the conjugation level of catechol estrogen in circulating blood with human serum albumin by LC-MS/MS using parallel reaction monitoring." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/d4557w.

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Jijana, Abongile Nwabisa. "Development of electrochemical ZnSe Quantam dots biosensors for low-level detection of 17β-Estradiol estrogenic endocrine disrupting compound." Thesis, 2010. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_7156_1305107269.

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<p>The main thesis hub was on development of two electrochemical biosensors for the determination of 17&beta<br>-estradiol: an estrogenic endocrine disrupting compound. Endocronology have significantly shown that the endocrine disruptors contribute tremendously to health problems encountered by living species today, problems such as breast cancer, reproductive abnormalities, a decline in male population most significant to aquatic vertebrates, reduced fertility and other infinite abnormalities recurring in the reproductive system of mostly male species. The first biosensor developed for the de
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