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Littérature scientifique sur le sujet « Fatty acids »

Auteur : Grafiati
Publié le 4 juin 2021
Mis à jour le 30 juillet 2024

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Articles de revues sur le sujet "Fatty acids"

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El-Shattory, Y., Saadia M. Aly et M. G. Megahed. « Propylenated fatty acids as emulsifiers ». Grasas y Aceites 50, no 4 (30 août 1999) : 264–68. http://dx.doi.org/10.3989/gya.1999.v50.i4.665.

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Feliu, María, Anabel Impa Condori, Inés Fernandez et Nora Slobodianik. « Omega 3 Fatty Acids vs Omega 6 Fatty Acids ». Current Developments in Nutrition 6, Supplement_1 (juin 2022) : 512. http://dx.doi.org/10.1093/cdn/nzac077.015.

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Abstract Objectives Dietary lipids have a very important role in nutrition and must be ingested in an appropriate proportion. Objective: To study the effect of w3 fatty acid supplementation of a diet containing sunflower oil (rich in fatty acids omega 6) as fat source, on serum fatty acid profiles of growing rats. Methods Weanling Wistar rats received during 10 days normocaloric diet and fat was provided by sunflower oil (S group). The others groups received the same diet supplemented with 24mg/day of fish oil (SF group) or chía oil (SCh group). Control group (C) received AIN´93 diet. Serum fatty acids profiles were determined by gas chromatography. Statistical analysis used ANOVA test. Results Results: (expressed as %Area) SERUM: OLEIC C:10.11 ± 1.84, S:12.13 ± 3.84, SCh:12.74 ± 1.56, SF: 13.12 ± 2.82; ARACHIDONIC C:13.40 ± 4.39, S:17.61 ± 4.09, SCh: 15.75 ± 0.89, SF:15.41 ± 1.76; LINOLEIC C:20.52 ± 3.37, S: 19.80 ± 3.36, SCh: 21.14 ± 2.12, SF: 18.92 ± 3.87; LINOLENIC (ALA) C:0.93 ± 0.27a, S:0.19 ± 0.06 b, SCh: 0.28 ± 0.08b, SF:0.22 ± 0.05b; EPA C:0.80 ± 0.22, S:0.68 ± 0.15, SCh: 0.74 ± 0.18, SF: 0.67 ± 0.14; DHA C:1.60 ± 0.55a, S:1.14 ± 0.35a, SCh:1.70 ± 0.45a, SF:4.22 ± 0.93b. Media that didn't present a letter (a, b) in common, were different (p < 0.01). In sera, S, SF and SCh groups showed lower ALA levels compared to C. SF group presented high levels of DHA. Diet S was mainly a contributor to linoleic acid with a ratio w6/w3 = 250 (recommended value: 5–10). Conclusions The diet containing sunflower oil as fat source shows that ω6 family route was exacerbated; by the other hand ω3 family was depressed. Chia supplement showed a tendency towards higher values of w3 family but were significantly lower than C. Fish oil supplement increase significantly DHA values. Diet containing sunflower oil as fat source provoked changes in serum fatty acids profiles and the supplementation with w3 fatty acid provided by chía or fish oil do not increase ALA values significantly. Diet influences the serum fatty acid profile, being not only important the percentage of lipids on it but also the different fatty acids pattern. Funding Sources UBACyT: 20020190100093BA.
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Vetter, Walter, et Christine Wendlinger. « Furan fatty acids - valuable minor fatty acids in food ». Lipid Technology 25, no 1 (janvier 2013) : 7–10. http://dx.doi.org/10.1002/lite.201300247.

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Azzoug, Saïd, et Djamila MESKINE. « Trans-fatty acids ». Batna Journal of Medical Sciences (BJMS) 6, no 1 (1 juillet 2019) : 15–17. http://dx.doi.org/10.48087/bjmsra.2019.6105.

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Les études ont montré que la consommation des acides gras trans provenant de l’hydrogénation industrielle partielle des huiles végétales était néfaste pour la santé en augmentant notamment le risque cardiométabolique ; leur consommation devrait donc être limitée voir interdite comme le suggèrent certaines recommandations. Mais d’un autre côté, certains acides gras trans naturels issus des ruminants pourraient être bénéfiques pour la santé et leur consommation ne devrait de ce fait pas être restreinte. L’effet des acides gras trans devrait donc être nuancé en fonction de leur origine naturelle ou industrielle.
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Holman, Ralph T. « ESSENTIAL FATTY ACIDS ». Nutrition Reviews 16, no 2 (27 avril 2009) : 33–35. http://dx.doi.org/10.1111/j.1753-4887.1958.tb00660.x.

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SUGANO, Michihiro, et Ikuo IKEDA. « Essential Fatty Acids ». Journal of Japan Oil Chemists' Society 40, no 10 (1991) : 831–37. http://dx.doi.org/10.5650/jos1956.40.831.

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&NA;. « Unsaturated fatty acids ». Reactions Weekly &NA;, no 495 (avril 1994) : 12. http://dx.doi.org/10.2165/00128415-199404950-00051.

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GURR, MICHAEL I. « Isomeric fatty acids ». Biochemical Society Transactions 15, no 3 (1 juin 1987) : 336–38. http://dx.doi.org/10.1042/bst0150336.

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Karmali, R. A. « Fatty acids : inhibition ». American Journal of Clinical Nutrition 45, no 1 (1 janvier 1987) : 225–29. http://dx.doi.org/10.1093/ajcn/45.1.225.

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GARTON, G. A. « Essential fatty acids ». Nutrition Bulletin 10, no 3 (septembre 1985) : 153–64. http://dx.doi.org/10.1111/j.1467-3010.1985.tb01207.x.

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Thèses sur le sujet "Fatty acids"

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Baker, Nancy Carol. « The Associations Among Dietary Fatty Acids, Plasma Fatty Acids, and Clinical Markers in Postmenopausal Women with Diabetes ». The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1253666943.

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Syed, Rahmatullah M. S. K. « Synthesis and physical properties of C18 azido-oxygenated and N-heterocyclic fatty acid derivatives ». Thesis, [Hong Kong : University of Hong Kong], 1991. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12964657.

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Huws, Enlli Haf. « Novel bio-active fatty acids ». Thesis, Bangor University, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.568810.

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New methods were developed to produce thiolated analogues of Mycobacteria components. Thiolated tuberculostearic acid, (S)-18-mercapto-l O-methyloctadecanoic acid, was firstly produced in seven steps in an overall yield of 7.6 %. This was followed by the first synthesis of a thiolated simple mycolic acid, the disulfide, ((2R,2' R,3R,3' R)- 2,2' - (disulfanediylbis(tetradecane-14, I-diyl))bis(3-hydroxyhenicosanoic acid, in 11 steps in an overall yield of 2.6 %. The first synthesis of a thiolated u-rnethyl-zrcns-cyclopropane methoxy mycolic acid was also achieved using the newly developed methods with the thiol introduced at two different positions within the molecule. (S,S,S,R,S,R,2R,2R')-26-26'- Disulfanediylbis(2-((R)-I-hydroxy-19-((1 S,2R)-2-((2S, 19S,20S)-19-methoxy-20- methyloctatriacontan-2-yl)cyclopropyl)nonadecyl)hexacosanoic acid, which includes the thiolated disulfide at the end of the a-alkyl chain, was synthesised in 18 steps from synthetically prepared starting materials in an overall yield of2.6 %. (S)-2-((S)-I-Hydroxy- 19-((1R,2S)-2-((2R, 19R,20R)-19-methoxy-20-methyloctatriacontan-2- yl)cyclopropyl)nonadecyl)-N-(2-((2-((R)-2-((R)-I-hydroxy-19-((IS,2R)-2-((2S, 19S,20S)- 19-methoxy- 20-methyloctatria-contan- 2- yl)cyclopropyl)nonadecyl)hexacosanamido )ethyl)disulfanyl)ethyl)hexacosan-amide, which contais a thiolated linker on the carboxylic acid, was synthesised in two steps from the free synthetic mycolic acid in an overall yield of 8.7 %. The different methods attempted for the formation of the thiolated analogues are discussed. To attempt to maximise the inhibitory effect of sterculic acid against Plasmodium falciparum /19 desaturase, which is essential for parasite growth, analogues of sterculic acid were designed and synthesised. 7-(2-0ctyl-cycloprop-l-enyl)-heptanoic acid methyl ester and 9-(2-octyl-cycloprop-l-enyl)-nonanoic acid methyl ester which contain one more and one less carbon atoms than sterculic acid in their chain lengths respectively were both synthesised in five steps in overall yields of 8 % and 4.6 % respectively. (±)-8-Methoxy-8- (2-octyl-cycloprop-l-enyl)-octanoic acid methyl ester was subsequently synthesised in three steps in an overall yield of 36 % whilst (±)-8-hydroxy-8-(2-octyl-cycloprop-l-enyl)- octanoic acid methyl ester was also synthesised in three steps in an overall yield of 25 %. In four steps both (± )-8-(tert-butyldimethylsilyloxy)-8-(2-octyl-cycloprop-l-enyl)-octanoic iii acid methyl ester and (±)-8-acetoxy-8-(2-octyl-cycloprop-I-enyl)-octanoic acid methyl ester were synthesised in an overall yield of 22.7 % and 34.9 % respectively. The inhibitory effects of these analogues were investigated.
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Pararasa, Chathyan. « Fatty acids, monocytes and ageing ». Thesis, Aston University, 2013. http://publications.aston.ac.uk/20894/.

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Elevated free fatty acids (FFA) are a feature of ageing and a risk factor for metabolic disorders such as cardiovascular disease (CVD) and type-2 diabetes (T2D). Elevated FFA contribute to insulin resistance, production of inflammatory cytokines and expression of adhesion molecules on immune cells and endothelial cells, risk factors for CVD and T2D. Molecular mechanisms of FFA effects on monocyte function and how FFA phenotype is affected by healthy ageing remain poorly understood. This thesis evaluated the effects of the two major FFA in plasma, oleate and palmitate on monocyte viability, cell surface antigen expression, and inflammatory activation in THP-1 monocytes. Palmitate but not oleate increased cell surface expression of CD11b and CD36 after 24h, independent of mitochondrial superoxide, but dependent on de novo synthesis of ceramides. LPS-mediated cytokine production in THP-1 monocytes was enhanced and decreased following incubation with palmitate and oleate respectively. In a model of monocyte-macrophage differentiation, palmitate induced a pro-inflammatory macrophage phenotype which required de novo ceramide synthesis, whilst oleate reduced cytokine secretion, producing a macrophage with enhanced clearance apoptotic cells. Plasma fatty acid analysis in young and mid-life populations revealed age-related increases in both the SFA and MUFA classes, especially the medium and very long chain C14 and C24 fatty acids, which were accompanied by increases in the estimated activities of desaturase enzymes. Changes were independently correlated with increased PBMC CD11b, plasma TNF-a and insulin resistance. In conclusion, the pro-atherogenic phenotype, enhanced LPS responses in monocytes, and pro-inflammatory macrophage in the presence of palmitate but not oleate is reliant upon de novo ceramide synthesis. Age-related increases in inflammation, cell surface integrin expression are related to increases in both the MUFA and SFA fatty acids, which in part may be explained by altered de novo fatty acid synthesis.
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Kishino, Shigenobu. « Production of conjugated fatty acids by lactic acid bacteria ». Kyoto University, 2005. http://hdl.handle.net/2433/86244.

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Kyoto University (京都大学)
0048
新制・課程博士
博士(農学)
甲第11617号
農博第1473号
新制||農||905(附属図書館)
学位論文||H17||N4010(農学部図書室)
UT51-2005-D366
京都大学大学院農学研究科応用生命科学専攻
(主査)教授 清水 昌, 教授 加藤 暢夫, 教授 植田 充美
学位規則第4条第1項該当
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Kew, Samantha. « Fatty acids and the immune system : dose response studies with n-3 polyunsaturated fatty acids ». Thesis, University of Southampton, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396188.

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Yu, Rong. « Metabolic interactions among amino acids, phospholipids and fatty acids ». Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/45211.

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Cystic fibrosis (CF) is the most common life-shortening disorder among Caucasians. Excessive faecal bile acid loss, increased oxidant stress, reduced plasma choline, increased oxidant stress, reduced glutathione and alterations in essential fatty acids are well recognized in patients with CF. It is also well-known that diabetes perturbs the methionine-homocysteine cycle. However, experimental data linking loss of amino acids in CF or decreased glucose availability in experimental diabetes to altered phospholipids and fatty acid metabolism are lacking. In the liver, bile acids are conjugated with glycine or taurine prior to secretion, and glycine de novo synthesis begins with glucose. Thus, the objectives of this thesis are: 1) to determine if inducing faecal bile acid loss will alter the methionine-homocysteine, and choline-betaine cycle metabolites, phospholipids and phospholipids n-6 and n-3 fatty acids, and 2) to show that experimental diabetes, which decreases glucose availability, alters methionine-homocysteine and choline-betaine cycle metabolites, phospholipids and phospholipid fatty acids in rats. Studies to address the first objective demonstrated that inducing faecal bile acid malabsorption leads to fat malabsorption with increased faecal total lipids and phospholipid excretion. This increased excretion was accompanied by increased plasma betaine concentration, decreased plasma triacylglycerol concentration, increased plasma and liver S-adenosylhomocysteine (SAH) concentration, and changes in the fatty acid composition of hepatic phospholipids. Studies to address the second objective showed that experimental diabetes led to increased plasma betaine concentration, decreased homocysteine concentration, increased liver phosphatidylethanolamine, decreased phosphatidylcholine, changes in the fatty acid composition of hepatic phospholipids, and abundance of the enzyme choline dehydrogenase. Thus, experimental diabetes, which reduces intracellular glucose availability, alters methionine-homocysteine and choline-betaine cycle metabolites, phospholipids and fatty acids. In conclusion, metabolism of phospholipids, their fatty acids, and the amino acids involved in the methionine-homocysteine cycle are inter-related.
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Peet, Daniel J. « Protein-bound fatty acids in mammalian hair fibres / ». Connect to thesis, 1994. http://eprints.unimelb.edu.au/archive/00000641.

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Sieberg, Maureen A. « Heritability and development of the free fatty acids and acylglycerideconstituent fatty acids in Vernonia galamensis oil ». Diss., The University of Arizona, 2003. http://hdl.handle.net/10150/280501.

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Since the mid-1970's, there has been active research on the development of Vernonia galamensis (Cass.) Less. as a potential new oilseed crop. Vernolic acid (cis-12:13-epoxy-cis-9-octadecenoic acid) comprises 70--75% of vernonia oil and is chemically reactive, affording it a variety of industrial applications. A concern in the domestication of an oilseed crop is to establish a breeding program to improve oil quality traits. The objectives of this research were to (1) develop a rapid procedure for seed analyses; (2) determine the development of vernonia oil; and (3) estimate the narrow-sense heritability (h 2) of oil quality traits. Successful separation of free fatty acids (FFA) and acylglycerides from small vernonia seed samples was achieved using aminopropyl solid phase extraction columns. Acylglycerides were eluted with a mixture of chloroform and isopropanol, while FFA were eluted with a mixture of acetone and trifluoroacetic acid. Four breeding lines from a collection of Vernonia galamensis held at the US Water Conservation Laboratory in Phoenix, AZ were used for the oil development study and grown in field trails in Phoenix and Tucson, Arizona. Seeds were collected on nine different days after flowering over the course of seed maturation. Seed samples were analyzed for FFA, acylglyceride constituent fatty acids, total acylglycerides, and total oil. In each breeding line, FFA content changed significantly throughout the course of the measurement period, and synthesis of acylglycerides constituent fatty acids followed a previously described pathway proceeding from C16:0 to C18:0 to C18:1 to C18:2 to C18:1 epoxy. Vernolic acid increased late in the measurement period, while total acylglycerides and total oil increased steadily over the period. Mature vernonia seed exhibited substantial variation in the amount of FFA, acylglyceride constituent fatty acids, total acylglycerides, and total oil. Sixty-nine half-sib families were created to study the heritability of FFA, vernolic acid, acylglycerides, and total oil production. Mature capitula were collected and analyzed individually for oil constituents. Narrow sense heritability estimates for these four oil quality traits were: FFA = 33%, vernolic acid = 65%, acylglycerides = 47%, and total oil = 50%. The results indicate potential for progress in selection for these traits.
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Barton, Louise Marie. « Polyunsaturated fatty acids and adrenal steroidogenesis ». Thesis, Royal Veterinary College (University of London), 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.519549.

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Livres sur le sujet "Fatty acids"

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Mostofsky, David I., Shlomo Yehuda et Norman Salem. Fatty Acids. New Jersey : Humana Press, 2001. http://dx.doi.org/10.1385/1592591191.

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Dhull, Sanju Bala, Sneh Punia et Kawaljit Singh Sandhu. Essential Fatty Acids. Sous la direction de Sanju Bala Dhull, Sneh Punia et Kawaljit Singh Sandhu. First edition. | Boca Raton : CRC, 2021. : CRC Press, 2020. http://dx.doi.org/10.1201/9780429321115.

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Dijkstra, Albert J., Richard J. Hamilton et Wolf Hamm, dir. Trans Fatty Acids. Oxford, UK : Blackwell Publishing Ltd, 2008. http://dx.doi.org/10.1002/9780470697658.

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BNF Task Force on Trans Fatty Acids., dir. Trans fatty acids. 2e éd. London : British Nutrition Foundation, 1995.

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J, Dijkstra Albert, Hamilton R. J et Hamm Wolf, dir. Trans fatty acids. Oxford : Blackwell Pub., 2008.

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BNF Task Force on Trans Fatty Acids., dir. Trans fatty acids. London : British Nutrition Foundation, 1987.

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Council, National Dairy, dir. Trans fatty acids. London : National Dairy Council, 1994.

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Shahidi, Fereidoon, et John W. Finley, dir. Omega-3 Fatty Acids. Washington, DC : American Chemical Society, 2001. http://dx.doi.org/10.1021/bk-2001-0788.

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Hegde, Mahabaleshwar V., Anand Arvind Zanwar et Sharad P. Adekar, dir. Omega-3 Fatty Acids. Cham : Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-40458-5.

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J, Binder Henry, Cummings John H et Soergel Konrad H, dir. Short chain fatty acids. Dordrecht : Kluwer Academic Publishers, 1994.

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Chapitres de livres sur le sujet "Fatty acids"

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Simopoulos, Artemis P. « Fatty Acids ». Dans Functional Foods, 355–92. Boston, MA : Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2073-3_16.

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Seigler, David S. « Fatty Acids ». Dans Plant Secondary Metabolism, 16–41. Boston, MA : Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-4913-0_2.

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Domínguez, Rubén, Laura Purriños, Mirian Pateiro, Paulo C. B. Campagnol, Jorge Felipe Reyes, Paulo E. S. Munekata et José Manuel Lorenzo. « Fatty Acids ». Dans Methods to Assess the Quality of Meat Products, 41–52. New York, NY : Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2002-1_4.

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Gómez-Cortés, Pilar, Manuela Juárez et Miguel Angel de la Fuente. « Fatty Acids ». Dans Handbook of Dairy Foods Analysis, 235–59. 2e éd. Second edition. | Boca Raton : CRC Press, 2021. : CRC Press, 2021. http://dx.doi.org/10.1201/9780429342967-11.

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Bährle-Rapp, Marina. « fatty acids ». Dans Springer Lexikon Kosmetik und Körperpflege, 202. Berlin, Heidelberg : Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_3922.

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Lopez, Annalaura, Federica Bellagamba et Vittorio Maria Moretti. « Fatty Acids ». Dans Handbook of Seafood and Seafood Products Analysis, 387–406. 2e éd. Boca Raton : CRC Press, 2024. http://dx.doi.org/10.1201/9781003289401-23.

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Dhull, Sanju Bala, et Sneh Punia. « Essential Fatty Acids ». Dans Essential Fatty Acids, 1–18. First edition. | Boca Raton : CRC, 2021. : CRC Press, 2020. http://dx.doi.org/10.1201/9780429321115-1.

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Singh, Ajay, Ramandeep Kaur, Pradyuman Kumar et Ashish Kumar Singh. « Dietary Fatty Acids ». Dans Essential Fatty Acids, 219–48. First edition. | Boca Raton : CRC, 2021. : CRC Press, 2020. http://dx.doi.org/10.1201/9780429321115-12.

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Petrovic, S., et A. Arsic. « Fatty Acids : Fatty Acids ». Dans Encyclopedia of Food and Health, 623–31. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-12-384947-2.00277-4.

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Sadler, M. J. « FATTY ACIDS | Trans Fatty Acids* ». Dans Encyclopedia of Human Nutrition, 230–37. Elsevier, 1998. http://dx.doi.org/10.1016/b0-12-226694-3/00121-6.

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Actes de conférences sur le sujet "Fatty acids"

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KRUMINA-ZEMTURE, Gita, et Ilze BEITANE. « FATTY ACID COMPOSITION IN BUCKWHEAT (FAGOPYRUM ESCULENTUM M.) FLOURS AND THEIR EXTRUDED PRODUCTS ». Dans RURAL DEVELOPMENT. Aleksandras Stulginskis University, 2018. http://dx.doi.org/10.15544/rd.2017.017.

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Lipids compose a small part of buckwheat seed, but they play an important role in the quality of food. The aim of this study was to evaluate the composition and content of fatty acids in different buckwheat flours (raw, roasted, white, black and germinated) and their extruded products. Fatty acids were quantified by gas chromatography according to the BIOR-T-012-131-2011 method. The prevalence of unsaturated fatty acids was determined which varied between 78.7 and 82.0 g 100 g-1 of fat in buckwheat samples. Linoleic and oleic acids were the most abundant unsaturated fatty acids, whereas palmitic acid was the main saturated fatty acid in buckwheat flours and their extruded products. Unsaturated/saturated fatty acid ratio was determined within 3.69 and 4.56, whereas linoleic/α-linolenic acid ratio was between 13.54 and 16.04. No trans-fatty acids in buckwheat flours and their extruded products were observed. The results showed that germination and extrusion of buckwheat flours did not have any effect on the content and composition of fatty acids (p>0.05).
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Bewick, Patrick, Eva Collakova et Bo Zhang. « Identification of Soybean Germplasm with Higher Concentrations of Long Chain Fatty Acids ». Dans 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/yetx4658.

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Fatty Acids are essential components of the diet and are critical for proper cell function. A balanced ratio of ω-3 to ω-6 fatty acids can be tied to positive human cardiovascular and autoimmune health. Aquaculture requires a much higher ratio. Soybean contains a substantial amount of fatty acids, but many varieties contain significantly higher concentrations of ω-6 fatty acids. The objective of this project was to identify soybean accessions with unique fatty acid profiles for genetic analysis to inform breeding decisions. Samples of 50 accessions originating from 16 countries were taken from seeds harvested in Blacksburg, VA in 2020. A gas chromatograph-flame ionization detector was used to quantify fatty acid levels and composition. Mass spectrometry was used to confirm the identity of peaks of interest. Fatty acid profiles for each sample were compared to the mean of all samples, and accessions with significantly different fatty acid concentrations were identified. These preliminary results will be used to inform future projects.
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Sakuradani, Eiji, Kai Yoshida, Naomi Murakawa et Takaiku Sakamoto. « Studies on filamentous fungus Fusarium sp. accumulating hydroxy fatty acids ». Dans 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/bmzp3848.

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Crude glycerol is produced as a by-product on a biodiesel production process. Effective utilization of this crude glycerol may help to reduce manufacturing costs and produce value-added products. We isolated microorganisms that grow in a medium containing crude glycerol as a major carbon source and analyzed their fatty acid composition. Fusarium sp. D2 was found to accumulate fatty acid secondary metabolites such as 10-hydroxystaric acid (HYB) and 10-oxostearic acid (KetoB). These fatty acids were converted form oleic acid containing crude glycerol as a component. We isolated a hydratase gene from strain D2 and characterized the hydratase by gene expression analysis using Escherichia coli. Strain D2 accumulates toxic fatty acids such as free fatty acids added in the medium. We aimed to use strain D2 as a host for the production of functional lipids that have been difficult to produce by fermentation. We tried to develop a host-vector system for strain D2. Here, we introduce studies on Fusarium sp. D2 accumulating hydroxy fatty acids.
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Petrović, Goran, Aleksandra Đorđević, Jelena Stamenković, Marija Dimitrijević, Jelena Nikolić, Vesna Stankov Jovanović et Violeta Mitić. « FATTY ACIDS CONTENT IN WATERMELON, MELON, SQUASH AND ZUCCHINI SEEDS ». Dans 2nd International Symposium on Biotechnology. Faculty of Agronomy in Čačak, University of Kragujevac, 2024. http://dx.doi.org/10.46793/sbt29.61gp.

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Seed samples of ten zucchini, melon, squash and watermelon samples were examined by gas chromatography-mass spectrometry (GC-MS) analysis for the presence of fatty acids. Fatty acid composition was significantly different among various samples. Hexadecanoic acid was found in all analyzed seed samples, whereas 9,12,15-octadecanoic acid was found only in zucchini seed samples. Unsaturated fatty acids, which possess multiple health benefits, were present in all samples, in various amounts. The high concentration of essential unsaturated fatty acids in analyzed seed samples indicates that they could be used as a source of these valuable compounds in human nutrition.
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Sugiyama, Takeshi, Alison J. Hobro, Takayuki Umakoshi, Prabhat Verma et Nicholas I. Smith. « Raman spectroscopy of macrophage uptake and cellular response during exposure to dietary lipids ». Dans JSAP-OSA Joint Symposia. Washington, D.C. : Optica Publishing Group, 2019. http://dx.doi.org/10.1364/jsap.2019.18p_e208_8.

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The increase in patients suffering from ‘lifestyle diseases such as coronary heart disease, atherosclerosis, diabetes and gout has been associated with the amount and nature of fats in our diets. In many of these diseases, macrophages and their role in lipid metabolism greatly impacts the development and severity of the disease. Fatty acids, which are a sub-class of lipids, have many different types depending on the number of carbon atoms and the presence of carbon double bonds (i.e. saturated and unsaturated fatty acids). The chemical properties of each fatty acid depend on the number of carbon atoms and degree of saturation. Therefore, it is important to investigate how macrophages metabolize these different types of fatty acids. In this research, we focus on the distribution and the uptake of four fatty acids: palmitic acid, stearic acid, oleic acid, and linoleic acid, shown in Table 1.
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Ghelmez, Mihaela A., Maria Honciuc et Elena Slavnicu. « Optical nonlinearities in fatty acids ». Dans ROMOPTO 2000 : Sixth Conference on Optics, sous la direction de Valentin I. Vlad. SPIE, 2001. http://dx.doi.org/10.1117/12.432881.

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« ASSOCIATION OF FREE FATTY ACID CONCENTRATIONS WITH GLUCOSE LEVELS IN BOSNIAN SUBJECTS ». Dans RAD Conference. RAD Centre, Niš, Serbia, 2023. http://dx.doi.org/10.21175/radproc.2023.09.

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Although there is considerable evidence suggesting a strong association of glucose, glycated hemoglobin and fatty acid levels with Type 2 diabetes mellitus (T2D), a limited number of studies have examined the association of individual fatty acids with disease progression. Acutely elevated plasma fatty acids stimulate insulin secretion while chronically elevated plasma fatty acids alter and disrupt insulin secretion. Furthermore, free fatty acids (FFA) are known to interfere with normal glucose homeostasis and affect pancreatic β-cell dysfunction. The study included 24 patients with newly diagnosed type 2 diabetes and 27 healthy controls, and analysis of the level of glucose and glycated hemoglobin was done by routine methods. The concentration of individual FFA was determined by gas chromatography with mass spectrometry detection. The results showed statistically significant differences in glucose, HbA1c, lipid profile, palmitic, linolenic, arachidonic, arachidonic, behenic acid as well as in DHA levels in all participants. In healthy subjects, no significant correlation was found between glucose and individual free fatty acids but a negative correlation was observed between DHA and glycated hemoglobin (p<0.05). Newly diagnosed diabetics showed a negative significant association between glucose and lauric acid concentrations, and also the association of glycated hemoglobin with myristic acid levels (p<0.01 and p<0.05, respectively). These data indicate the association of different types of free fatty acids with glucose levels and their control in the serum of healthy and newly diagnosed type 2 diabetics, and therefore indicate the importance of monitoring glucose levels as well as glycated hemoglobin with concentrations of individual free fatty acids in the progression of diabetes.
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Ruths, M., S. Lundgren, K. Danerlo¨v et K. Persson. « Tribological Properties of Physisorbed, Unsaturated Fatty Acids ». Dans STLE/ASME 2008 International Joint Tribology Conference. ASMEDC, 2008. http://dx.doi.org/10.1115/ijtc2008-71164.

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We have measured normal and lateral (friction) forces across films of saturated and unsaturated fatty acids with the Surface Forces Apparatus (SFA). When adsorbed onto mica from n-hexadecane, linoleic acid forms a dimer layer between monolayer-covered surfaces. This dimer layer, which is not observed in stearic or oleic acid, is removed at low loads. The remaining linoleic acid monolayers are thinner than the ones formed by stearic and oleic acid, and show a more complex friction response with two regimes of linear friction, higher stability at very high loads, and a dependence of the friction on sliding speed and adsorption time.
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Ramasamy, Jothibasu, et Mohammad K. Arfaj. « Sustainable and Eco-Friendly Drilling Fluid Additives Development ». Dans International Petroleum Technology Conference. IPTC, 2022. http://dx.doi.org/10.2523/iptc-22455-ms.

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Abstract Drilling fluid is an inseparable component of drilling oil and gas wells and circulated from the day of spudding to the day of completing a well. Drilling fluid consists of a variety of chemicals to provide various properties to drilling fluid such as viscosity, fluid loss control, emulsion stability, lubricity, etc. Developing chemicals that are eco-friendly and sustainable to provide the above-mentioned properties to drilling fluid is a significant step forward taken towards sustainability and reducing carbon footprint besides suitability for aquifers and offshore environments. Several fatty acid-based products play a crucial role in drilling fluids additives development as fatty acids offer eco-friendly and bio-degradable properties. Triglycerides present in vegetable oil is a potential source of fatty acids and their derivatives. Used cooking oil (UCO) provides a perpetual and sustainable source of raw material for various types of eco-friendly additives development. Used cooking oil is subjected to simple chemical modification of base hydrolysis process and mixture of fatty acids have been obtained after completing a sequence of clean-up process of reaction mixture. The fatty acids obtained are eco-friendly, bio-degradable and non-toxic. Due to technical, economic and environmental benefits, we have conducted several research projects to develop various chemicals from used cooking oil for oil and gas field applications. Fatty acid-based products mainly used in drilling fluids as lubricants to reduce torque and drag for water-based mud. In case of oil-based mud systems, fatty acid derived products are used as emulsifiers, wetting agents and rheology modifiers. However, these products have been either mixture of fatty acids and their derivatives or only derivatives of fatty acids. In our study, we have used the mixture of fatty acids obtained from chemical conversion of UCO for applications as lubricant for water-based mud and emulsifier and rheology modifier for invert emulsion oil-based mud systems. This paper describes the chemicals process for converting used cooking oil to fatty acids by base hydrolysis reaction in the first section. Application of synthesized fatty acids for water-based and oil-based mud formulation as lubricants, emulsifiers and rheology modifiers have been discussed in the second part of the paper.
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Hobro, Alison J., Takeshi Sugiyama, Nicolas Pavillon, Takayuki Umakoshi, Prabhat Verma et Nicholas Smith. « Label-free Raman imaging of saturated and unsaturated fatty acid uptake, storage, and return toward baseline levels in macrophages ». Dans JSAP-Optica Joint Symposia. Washington, D.C. : Optica Publishing Group, 2023. http://dx.doi.org/10.1364/jsapo.2023.19a_a602_1.

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Lipids play many important roles in the body including cell signaling and energy storage. The presence of excessive lipids, or disruption of normal lipid metabolic processes in the cell, has been linked to lifestyle diseases such as atherosclerosis and obesity. Where the affected cells are part of the innate immune system such dysregulation of lipids has also been implicated in impaired immune responses to infection. Therefore, understanding how macrophages are affected by the presence of fatty acids in their local environment is an important step in understanding lifestyle disease development. Using Raman spectroscopic imaging we studied the uptake of several concentrations of palmitic, stearic, oleic and linoleic acid in live macrophage cells. Macrophages readily take up these lipids, which can be observed by Raman imaging at the edge of the cytoplasm close to the cell membrane, with the exact distribution dependent on the nature of the fatty acid (unsaturated/saturated) and the exposure concentration. At the highest concentrations, all fatty acids appear to be toxic to the macrophage cells after 24 hours of exposure. By comparing the Raman intensities of the pure fatty acids and ratiometric imaging of the intensities within the macrophage cells we were able to determine that the toxicity of a fatty acid is not due directly to the amount of fatty acid present in the macrophage, rather the nature of the fatty acid is important. This demonstrates the power of high-resolution ratiometric Raman imaging for bioanalysis. In addition, we monitored macrophage cells after removing fatty acids from the surrounding environment, observing a reduction in fatty acid content of the cells over the following 48 hours, showing that even heavily lipid-laden macrophages can process these excess lipids once fatty acids are removed from the environment.
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Rapports d'organisations sur le sujet "Fatty acids"

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Knapp, Jr ,. F. F. (Radioiodinated free fatty acids). Office of Scientific and Technical Information (OSTI), décembre 1987. http://dx.doi.org/10.2172/7044018.

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Risk Assessment, FSA Regulated Products. Safety Assessment : Outcome of assessment of Cetylated Fatty Acids as a Novel Food. Food Standards Agency, août 2023. http://dx.doi.org/10.46756/sci.fsa.loq953.

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An application was submitted to the Food Standards Agency (FSA) and Food Standards Scotland (FSS) in February 2021 from Pharmaneutra S.p.a., Italy (“the applicant”) for the authorisation of cetylated fatty acids as a novel food. The novel food is a mixture of cetylated fatty acids, cetyl myristate and cetyl oleate, which are synthesised from cetyl alcohol with myristic acid and, cetyl alcohol with oleic acid, respectively. These two cetylated fatty acids are then blended with olive oil to give a finished product containing 70 – 80% cetylated fatty acids. The application is a new application, seeking to use cetylated fatty acids within the food category: food supplements. To support the FSA and FSS in their evaluation of the application, the Advisory Committee on Novel Foods and Processes (ACNFP) were asked to review the safety dossier and supplementary information provided by the applicant. The Committee concluded that the applicant had provided sufficient information to assure the novel food, cetylated fatty acids, was safe under the proposed conditions of use. The anticipated intake levels and the proposed use in foods and food supplements was not considered to be nutritionally disadvantageous and does not mislead consumers. The views of the ACNFP have been taken into account in this safety assessment which represents the opinion of the FSA and FSS on cetylated fatty acids.
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Hofstad, Beth. Engineering Fatty Acid Synthesis in Rhodosporidium Toruloides to Produce Mid-Chain Fatty Acids and Fatty Alcohols - CRADA 501. Office of Scientific and Technical Information (OSTI), février 2021. http://dx.doi.org/10.2172/1827799.

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Stambuli, James P., et S. M. Whittemore. Site-selective Alkane Dehydrogenation of Fatty Acids. Fort Belvoir, VA : Defense Technical Information Center, décembre 2011. http://dx.doi.org/10.21236/ada566294.

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Lee, E. J., et Dong U. Ahn. Production of Volatiles from Fatty Acids and Oils by Irradiation. Ames (Iowa) : Iowa State University, janvier 2004. http://dx.doi.org/10.31274/ans_air-180814-1038.

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Liu, Yiliang. Omega-3 Fatty Acids and a Novel Mammary Derived Growth Inhibitor Fatty Acid Binding Protein MRG in Suppression of Mammary Tumor. Fort Belvoir, VA : Defense Technical Information Center, juillet 2001. http://dx.doi.org/10.21236/ada396066.

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Liu, Yiliang E. Omega-3 Fatty Acids and a Novel Mammary Derived Growth Inhibitor Fatty Acid Binding Protein MRG in Suppression of Mammary Tumor. Fort Belvoir, VA : Defense Technical Information Center, juillet 2002. http://dx.doi.org/10.21236/ada408070.

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Balk, Ethan M., Gaelen P. Adam, Valerie Langberg, Christopher Halladay, Mei Chung, Lin Lin, Sarah Robertson et al. Omega-3 Fatty Acids and Cardiovascular Disease : An Updated Systematic Review. Agency for Healthcare Research and Quality, août 2016. http://dx.doi.org/10.23970/ahrqepcerta223.

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Márquez-Ruiz, Gloria. Separation and Quantification of Oxidized Monomeric, Dimeric and Oligomeric Fatty Acids. AOCS, décembre 2011. http://dx.doi.org/10.21748/lipidlibrary.39201.

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Sukenik, Assaf, Paul Roessler et John Ohlrogge. Biochemical and Physiological Regulation of Lipid Synthesis in Unicellular Algae with Special Emphasis on W-3 Very Long Chain Lipids. United States Department of Agriculture, janvier 1995. http://dx.doi.org/10.32747/1995.7604932.bard.

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Various unicellular algae produce omega-3 (w3) very-long-chain polyunsaturated fatty acids (VLC-PUFA), which are rarely found in higher plants. In this research and other studies from our laboratories, it has been demonstrated that the marine unicellular alga Nannochloropsis (Eustigmatophyceae) can be used as a reliable and high quality source for the w3 VLC-PUFA eicosapentaenoic acid (EPA). This alga is widely used in mariculture systems as the primary component of the artificial food chain in fish larvae production, mainly due to its high EPA content. Furthermore, w3 fatty acids are essential for humans as dietary supplements and may have therapeutic benefits. The goal of this research proposal was to understand the physiological and biochemical mechanisms which regulate the synthesis and accumulation of glycerolipids enriched with w3 VLC-PUFA in Nannochloropsis. The results of our studies demonstrate various aspects of lipid synthesis and its regulation in the alga: 1. Variations in lipid class composition imposed by various environmental conditions were determined with special emphasis on the relative abundance of the molecular species of triacylglycerol (TAG) and monogalactosyl diacylglycerol (MGDG). 2. The relationships between the cellular content of major glycerolipids (TAG and MGDG) and the enzymes involved in their synthesis were studied. The results suggested the importance of UDP-galactose diacylglycerol galactosyl (UDGT) in regulation of the cellular level of MGDG. In a current effort we have purified UDGT several hundredfold from Nannochloropsis. It is our aim to purify this enzyme to near homogeneity and to produce antibodies against this enzyme in order to provide the tools for elucidation of the biochemical mechanisms that regulate this enzyme and carbon allocation into galactolipids. 3. Our in vitro and in vivo labeling studies indicated the possibility that phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are associated with desaturation of the structural lipids, whereas shorter chain saturated fatty acids are more likely to be incorporated into TAG. 4. Isolation of several putative mutants of Nannochloropsis which appear to have different lipid and fatty acid compositions than the wild type; a mutant of a special importance that is devoid of EPA was fully characterized. In addition, we could demonstrate the feasibility of Nannochloropsis biomass production for aquaculture and human health: 1) We demonstrated in semi-industrial scale the feasibility of mass production of Nannochloropsis biomass in collaboration with the algae plant NBT in Eilat; 2) Nutritional studies verified the importance algal w3 fatty acids for the development of rats and demonstrated that Nannochloropsis biomass fed to pregnant and lactating rats can benefit their offspring.
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