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Littérature scientifique sur le sujet « Flavonoids Flavonoids »

Auteur : Grafiati

Publié le 4 juin 2021

Mis à jour le 1 février 2022

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Articles de revues sur le sujet "Flavonoids Flavonoids"

Ivey, Kerry L., Jonathan M. Hodgson, Kevin D. Croft, Joshua R. Lewis et Richard L. Prince. « Flavonoid intake and all-cause mortality ». American Journal of Clinical Nutrition 101, n^o 5 (1 avril 2015) : 1012–20. http://dx.doi.org/10.3945/ajcn.113.073106.

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ABSTRACT Background: Flavonoids are bioactive compounds found in foods such as tea, chocolate, red wine, fruit, and vegetables. Higher intakes of specific flavonoids and flavonoid-rich foods have been linked to reduced mortality from specific vascular diseases and cancers. However, the importance of flavonoids in preventing all-cause mortality remains uncertain. Objective: The objective was to explore the association between flavonoid intake and risk of 5-y mortality from all causes by using 2 comprehensive food composition databases to assess flavonoid intake. Design: The study population included 1063 randomly selected women aged >75 y. All-cause, cancer, and cardiovascular mortalities were assessed over 5 y of follow-up through the Western Australia Data Linkage System. Two estimates of flavonoid intake (total flavonoidUSDA and total flavonoidPE) were determined by using food composition data from the USDA and the Phenol-Explorer (PE) databases, respectively. Results: During the 5-y follow-up period, 129 (12%) deaths were documented. Participants with high total flavonoid intake were at lower risk [multivariate-adjusted HR (95% CI)] of 5-y all-cause mortality than those with low total flavonoid consumption [total flavonoidUSDA: 0.37 (0.22, 0.58); total flavonoidPE: 0.36 (0.22, 0.60)]. Similar beneficial relations were observed for both cardiovascular disease mortality [total flavonoidUSDA: 0.34 (0.17, 0.69); flavonoidPE: 0.32 (0.16, 0.61)] and cancer mortality [total flavonoidUSDA: 0.25 (0.10, 0.62); flavonoidPE: 0.26 (0.11, 0.62)]. Conclusions: Using the most comprehensive flavonoid databases, we provide evidence that high consumption of flavonoids is associated with reduced risk of mortality in older women. The benefits of flavonoids may extend to the etiology of cancer and cardiovascular disease.

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Wollenweber, Eckhard, Marion Dörr et Matthias Christ. « Flavonoid Aglycones from the Leaf and Stem Exudates of Some Geraniaceae Species ». Natural Product Communications 6, n^o 1 (janvier 2011) : 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600105.

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Six species of Pelargonium and one species of Geranium were studied for their surface flavonoids. Some of them were found to exhibit an unexpectedly high number of methylated flavonoids, mostly flavonols. The chemotaxonomic significance of exudate flavonoid diversification is shortly addressed.

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Nikolova, M., et S. Ivancheva. « Distribution of Surface Flavonoids in Bulgarian Plants ». Natural Product Communications 1, n^o 11 (novembre 2006) : 1934578X0600101. http://dx.doi.org/10.1177/1934578x0600101119.

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The review describes the distribution of surface flavonoids in Bulgarian plants. More than 100 species of Asteraceae, Lamiaceae, Scrophulariaceae, Geraniaceae and other families have been checked for external flavonoid aglycones. The flavonoid profiles of Asteraceae species are composed of a wide array of flavones and flavonols, mainly based upon 6-substituted derivatives. Flavone aglycones are predominant in the exudates of Lamiaceae species. Apigenin, luteolin and their derivatives were most commonly found in the studied species of Scropulariaceae and Lamiaceae. It has been shown that species of Geraniaceae, Ranunculaceae, and Solanaceae contain flavonoids of the flavonol class as surface constituents. Surface distributed flavonoids appear to have been well studied and useful for chemotaxonomy. If there is not too much infraspecific variation, flavonoid profiles can be used as taxonomic characters to distinguish species. Correlations between external flavonoid formation and local environment are apparent.

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Li, Chengshuai, Lijing Zhang, Decao Niu, Shuzhen Nan, Xiumei Miao, Xiaowei Hu et Hua Fu. « Investigation of flavonoid expression and metabolite content patterns during seed formation of Artemisia sphaerocephala Krasch. » Seed Science Research 31, n^o 2 (juin 2021) : 136–48. http://dx.doi.org/10.1017/s096025852100012x.

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AbstractFlavonoids are a group of phenolic secondary metabolites in plants that have important physiological, ecological and economic value. In this study, using the desert plant Artemisia sphaerocephala Krasch. as the sample material, the content and components of the total flavonoids in its seeds at seven different developmental stages were determined. In addition, the genes involved in flavonoid metabolism were identified by full-length transcriptome sequencing (third-generation sequencing technology based on PacBio RS II). Their expression levels were analysed by RNA-seq short reading sequencing, to reveal the patterns and regulation mechanisms of flavonoid accumulation during seed development. The key results were as follows: the content of total flavonoids in mature seeds was 15.05 mg g−1, including five subclasses: flavonols, chalcones, flavones, flavanones and proanthocyanidins, among which flavonols accounted for 45.78%. The period of rapid accumulation of flavonoids was 40–70 d following anthesis. The high expression of phenylalanine ammonia-lyase (PAL), 4-coumarate-CoA ligase (4CL) and UDP-glucose:flavonoids 3-o-glucosyltransferase (UF3GT) promoted the accumulation of total flavonoids, while the high expression of flavonoids 3′-hydroxylase (F3′H) and flavonols synthase (FLS) made flavanols the main component. Transcription factors such as the MYB-bHLH-WDR (MBW) complex and Selenium-binding protein (SBP) directly regulated the structural genes of flavonoid metabolism, while C2H2-type zinc finger (C2H2), Zinc-finger transcription factor (GATA), Dehydration-responsive element binding (DREB), Global Transcription factor Group E protein (GTE), Trihelix DNA-binding factors (Trihelix) and Phytochrome-interacting factor (PIF) indirectly promoted the synthesis of flavonoids through hormones such as brassinoidsteroids (BRs) and abscisic acid (ABA). These results provided valuable resources for the application of related genes in genetics and breeding.

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Iwashina, Tsukasa. « FLAVONOIDS IN THE SPECIES OF THE FAMILY ARACEAE : A REVIEW ». Buletin Kebun Raya 23, n^o 1 (30 avril 2020) : 1–24. http://dx.doi.org/10.14203/bkr.v23i1.1.

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Flavonoids is one of the secondary metabolites and consists of two phenyl rings (A- and B-rings) connected by a three carbon bridge. Over 8000 kinds of flavonoids were reported from vascular plants and Bryophytes. This paper reviewed the flavonoid characters of the Araceae s.l. (including the Lemnaceae). Major flavonoids of the family were C-glycosylflavones with the exception for subfamilies Gymnostachydoideae and Orontioideae. Other flavonoid classes, i.e. anthocyanins, flavones, flavonols, flavan and proanthocyanidins, were reported in all subfamilies. Flavanone and C-glycosylflavanone were isolated from Spirodela polyrhiza and Anthurium binotii, respectively. However, dihydroflavonol, chalcone, dihydrochalcone, aurone, and isoflavonoids were not reported in the Araceae. Although Araceae s.l. is a large family consisting of ca. 3645 species and ca. 144 genera, flavonoids were surveyed only in 146 species of 48 genera, as far as known.

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Kim, Bo-Ram, Ah-Reum Han et Ik-Soo Lee. « Microbial Transformation of Flavonoids in Cultures of Mucor hiemalis ». Natural Product Communications 15, n^o 12 (décembre 2020) : 1934578X2097774. http://dx.doi.org/10.1177/1934578x20977743.

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Flavonoids are plant secondary metabolites that are well known for their health-promoting properties as nutraceuticals in diets. Bioavailability and biological activities of flavonoids vary among the individual subclasses with different patterns of substitution, inclusive of glycosylation, to their basic structures. Many flavonoids exist as glycosides in plants. This study investigated the possibility of glycosylation of flavonoids through biotransformation using filamentous fungi as whole-cell biocatalysts. Microbial transformations of ten flavonoids (four flavones, four flavonols, a flavanone, and an aurone) were performed in cultures of Mucor hiemalis KCTC 26779. As a result, a flavonoid glycoside was obtained which has not been described previously. The chemical structure of this product was elucidated as 6,2′-dimethoxyflavonol-3- O-β-d-glucopyranoside by analyzing 1-dimensional and 2-dimensional-nuclear magnetic resonance spectral and high-resolution electrospray ionization mass spectral data. This compound could be useful for further biological and bioavailability studies, as well as expanding the library of flavonoid derivatives.

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Rasmussen et Breinholt. « Non-Nutritive Bioactive Food Constituents of Plants : Bioavailability of Flavonoids ». International Journal for Vitamin and Nutrition Research 73, n^o 2 (1 mars 2003) : 101–11. http://dx.doi.org/10.1024/0300-9831.73.2.101.

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Flavonoids are polyphenols widely distributed in the plant kingdom, and are present in fruits andvegetables regularly consumed by humans. In vitro metabolic studies of flavonoids in rat liver microsomes identified the 3’, 4’-dihydroxylated derivatives as the major metabolic endpoint. However, in vivo in rats almost none of this metabolite and only minor amounts of the 4’-monohydroxylated derivative was produced. Flavonoids with the 4’-monohydroxylated structure were generally not metabolised and were excreted unchanged in urine in higher amounts than other flavonoids investigated. It has for long been a controversy, whether flavonoids are absorbed as the intact glycoside or whether they have to be hydrolysed to the free aglycon prior to absorption. Recent data suggest that b-glucosidases and maybe also lactase phlorizin hydrolase (LPH) in the small intestine are capable of hydrolysing flavonoid glucosides and these compounds are thus taken up as the free aglycon and not as the intact glycosides. LC-MS analyses of 12 dietary flavonoids in human urine showed that no flavonoid glycosides were excreted, and that the citrus flavanones and phloretin are excreted in higher amounts than the flavonols. Furthermore, total flavonoid excretion may be a useful biomarker for habitual fruit and vegetable consumption.

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Wang, Lanxiang, Pui Ying Lam, Andy C. W. Lui, Fu-Yuan Zhu, Mo-Xian Chen, Hongjia Liu, Jianhua Zhang et Clive Lo. « Flavonoids are indispensable for complete male fertility in rice ». Journal of Experimental Botany 71, n^o 16 (9 mai 2020) : 4715–28. http://dx.doi.org/10.1093/jxb/eraa204.

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Abstract Flavonoids are essential for male fertility in some but not all plant species. In rice (Oryza sativa), the chalcone synthase mutant oschs1 produces flavonoid-depleted pollen and is male sterile. The mutant pollen grains are viable with normal structure, but they display reduced germination rate and pollen-tube length. Analysis of oschs1/+ heterozygous lines shows that pollen flavonoid deposition is a paternal effect and fertility is independent of the haploid genotypes (OsCHS1 or oschs1). To understand which classes of flavonoids are involved in male fertility, we conducted detailed analysis of rice mutants for branch-point enzymes of the downstream flavonoid pathways, including flavanone 3-hydroxylase (OsF3H; flavonol pathway entry enzyme), flavone synthase II (CYP93G1; flavone pathway entry enzyme), and flavanone 2-hydroxylase (CYP93G2; flavone C-glycoside pathway entry enzyme). Rice osf3h and cyp93g1 cyp93g2 CRISPR/Cas9 mutants, and cyp93g1 and cyp93g2 T-DNA insertion mutants showed altered flavonoid profiles in anthers, but only the osf3h and cyp93g1 cyp93g2 mutants displayed reduction in seed yield. Our findings indicate that flavonoids are essential for complete male fertility in rice and a combination of different classes (flavanones, flavonols, flavones, and flavone C-glycosides) appears to be important, as opposed to the essential role played primarily by flavonols that has been previously reported in several plant species.

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Wollenweber, Eckhard, et Marion Dörr. « Exudate Flavonoids of Some Juglandaceae ». Natural Product Communications 4, n^o 2 (février 2009) : 1934578X0900400. http://dx.doi.org/10.1177/1934578x0900400208.

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Six species of Juglandaceae have been checked for the occurrence of flavonoid aglycones on their leaf and fruit surfaces. Except for one, they exhibit flavonols, mostly methyl ethers of kaempferol and quercetin, including 6- O-substituted derivatives. Apigenin and acacetin are the only flavones found so far. Flavonoids accumulated on leaves are different from those excreted on green fruits. It has become evident that in future studies greater attention must be paid to the localization of flavonoid aglycones in different plant organs.

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Karapandzova, Marija, Gjose Stefkov, Ivana Cvetkovikj, Jasmina Petreska Stanoeva, Marina Stefova et Svetlana Kulevanova. « Flavonoids and Other Phenolic Compounds in Needles of Pinus peuce and Other Pine Species from the Macedonian Flora ». Natural Product Communications 10, n^o 6 (juin 2015) : 1934578X1501000. http://dx.doi.org/10.1177/1934578x1501000647.

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Flavonoids and other phenolic compounds in young needles of four pine species, Pinus peuce, P. nigra, P. mugo and P. sylvestris from the Macedonian flora were investigated. The amount of total phenols and total flavonoids were determined using Folin-Ciocalteau and aluminum chloride assay, respectively. The obtained results revealed that the total phenolic content (TPC) and total flavonoids content (TFC) varied among different pine species ranging from 9.8 to 14.0 mg GAE/g and from 3.3 to 7.2 mg CE/g of dried plant material, respectively. Qualitative analysis of flavonoids and other phenolic components was made by a LC-DAD/ESI-MSn optimized chromatographic method. A total of 17 phenolic components were identified and classified as: acids (2), procyanidins (2) and flavonoid glycosides (13). The most prevalent components were flavonoid glycosides, especially flavonols and methylated flavonols (9). Additionally, 3 components were found as acylated flavonol glycosides with ferulic and p-coumaric acid. The last one was found not only in esterified form but also in the free form. Only one flavone-apigenin glycoside was detected. Procyanidins were identified as catechin derivatives, both dimers and trimers.

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Thèses sur le sujet "Flavonoids Flavonoids"

Coqueiro, Aline [UNESP]. « Fracionamento bioguiado para selação de substâncias antioxidante, antimalárica e antibiótica potenciais nas espécies Kielmeyera variabilis (Clusiaceae) e Brosimum Glaziovii (Moraceae) ». Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/105815.

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Made available in DSpace on 2014-06-11T19:35:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-10-22Bitstream added on 2014-06-13T20:06:35Z : No. of bitstreams: 1 coqueiro_a_dr_araiq.pdf: 3444220 bytes, checksum: af4b8398d8cad29c3d2633b22662e0d8 (MD5)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Os testes biológicos realizados por pesquisadores colaboradores do NuBBE para as espécies selecionadas para este estudo Brosimum glaziovii e Kielmeyera variabilis indicaram K. variabilis como uma importante fonte de metabólitos especiais bioativos. O fracionamento bioguiado da fração AcOEt dos galhos de K. variabilis para isolamento de substâncias com potencial antimalárico foi realizado via teste químico com -hematina e in vitro com Plasmodium falciparum, levando a identificação das xantonas oxigenadas 3,6-diidroxi-1,4,8-trimetoxixantona, 3,5-diidroxi-4-metoxixantona, 3,4-diidroxi-6,8-dimetoxixantona, 3,4-diidroxi-2-metoxixantona, 5-hidroxi-1,3- dimetoxixantona, 2,3-dimetoxi-4-hidroxixantona, 3-hidroxi-2-metoxixantona e 2-hidroxi- 1-metoxi-xantona e o xantonolignóide kielcorina. Dentre as substâncias isoladas, o xatonolignóide kielcorina foi considerado ativo quando comparado ao padrão cloroquina. A avaliação do potencial tripanocida também foi realizada para as xantonas isoladas e dentre estas, a 3,4-diidroxi-2-metoxixantona foi a mais ativa, principalmente para a cepa resistente ao benzonidazol (cepa Bolívia). Na fração EHFB das folhas de B. glaziovii foi observado o potencial antichagásico desta espécie. Os resultados observados para os ensaios antioxidantes levaram ao isolamento dos flavonóides quercitrina, podocarpusflavona A e da mistura de quercetina-3-Oglicosídeo e quercetina-3-O-galactosídeo, evidenciando a importância dos grupos catecólicos na potencialização da ação antioxidante. O estudo bioguiado pela atividade antimicrobiana com seis cepas de Staphylococcus aureus resistentes à meticilina culminou no isolamento de um derivado prenilado do floroglucinol (HGK-1) o qual demonstrou ser responsável pela potente atividade demonstrada pela fração hexânica dos galhos de K. variabilis. As xantonas isoladas tiveram seu potencial antimicrobiano...
Several biological activities have been carried out by NuBBE’s collaborators aiming the identification of active extracts from plant species, and Brosimum glaziovii and Kielmeyera variables showed to be important sources of bioactive secondary metabolites. Bio-guided fractionation of the EtOAc bioactive fraction of the branches of K. variabilis by using of the chemical test -hematin, and in vitro by using of Plasmodium falciparum, led to the isolation and identification of oxygenated xanthones 3,6-dihydroxy-1,4,8-trimethoxyxanthone, 3,5-dihydroxy-4-methoxyxanthone, 3,4- dihydroxy-6,8-dimethoxyxanthone, 3,4-dihydroxy-2-methoxyxanthone, 1,3-dimethoxy- 5-hydroxyxanthone, 2,3-dimethoxy-4-hydroxyxantona, 3-hydroxy-2-methoxyxanthone and 2-hydroxy-1-methoxyxanthone and xantonolignoid kielcorin. Among the compounds isolated, the xatonolignoid keilcorine indicated activity when compared to the standard chloroquine. The assessment of potential trypanocidal was also a part of this work and among the isolated xanthones, 3,4-dihydroxy-2-methoxyxanthone showed to be the most active, especially against the resistant strain to benzonidazole (Bolivia strain). In hexane fraction of leaves from B. glaziovii was noted antichagasic potencial for this specie. The antioxidant test used in this study led to the isolation of several flavonoids with antioxidant activity: quercitrin, podocarpusflavone A and the mixture of quercetin-3-O-glucoside and quercetin-3-O-galactoside, showing the importance of catechol group for the potentiating of antioxidant activity. The bio-guided antimicrobial activity using six strains of methicillin-resistant Staphylococcus aureus resulted in the isolation of the prenylated phloroglucinol derivative (HGK-1), which proved to be responsible for the potent activity exhibited by the hexane extract of the branches of K. variabilis. The xanthones isolated were evaluated... (Complete abstract click electronic access below)

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Roedig-Penman, Andrea. « Flavonoids as antioxidants ». Thesis, University of Reading, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363806.

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Pereira, Gabriela Sterle. « Ação inibitória dos flavonoides quercetina e rutina sobre a ativação de neutrófilos humanos / ». Assis, 2017. http://hdl.handle.net/11449/150482.

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Orientadora: Karina Alves de Toledo
Banca: Luis Octávio Regasini
Banca: Flávia Aparecida Paina Brasil
Resumo: Rutina e Quercetina são flavonoides encontrados em diversos alimentos, incluindo aqueles indicados como complemento no tratamento de doenças inflamatórias. Durante o processo inflamatório, neutrófilos são as primeiras células a serem recrutadas por estarem diretamente relacionadas à ativação e resolução destes processos. Assim, frequentemente estas células são alvos para novos compostos anti-inflamatórios. A descrição da atividade anti-inflamatória de rutina e quercetina se estende para vários ativadores das vias clássicas dos neutrófilos. O estudo quanto aos compostos forbol ésteres, como PMA (phorbol myristate acetate), que ativam de maneira específica a sinalização da proteína quinase C, ainda são escassos.O objetivo deste trabalho foi analisar a atividade anti-inflamatória de rutina e quercetina sobre neutrófilos ativados por PMA. Para tanto, foram analisadas etapas importantes do processo inflamatório mediadas pelos neutrófilos: adesão, desgranulação, e liberação das NETs (Neutrophil Extracelular Traps). Nossos resultados demonstraram que, ativação de neutrófilos por PMA: (i) rutina e quercetina não inibem a adesão dos neutrófilos, (ii) quercetina inibe a desgranulção, (iii) ambos inibem a atividade da mieloperoxidase (MPO), assim como (iv) inibem a liberação das NETs na ausência de morte celular. Análises de docking molecular sugerem que tais eventos podem estar relacionados à geração de complexos quercetina/MPO e rutina/elastase
Abstract: Rutin and Quercetin are flavonoids found in several foods, including those indicated as a supplement in the inflammatory treatment diseases. During the inflammatory process, neutrophils are the first cells to be recruited. They are directly related to the activation and resolution of these processes. Thus, these cells often target new antiinflammatory compounds. The description of the anti-inflammatory activity of rutin and quercetin extends to several activators of classical neutrophil pathways. Studies involving forbol esters compounds, as PMA ((phorbol myristate acetate), which activate in a specific manner the protein kinase signalling, it is still poor. The aim of this study was to analyze the anti-inflammatory activity of rutin and quercetin on PMAactivated neutrophils. For this, important steps of the inflammatory process mediated by neutrophils were analyzed: adhesion, degranulation, and release of NETs (Neutrophil Extracelular Traps). Our results demonstrated that neutrophil activation by PMA: (i) rutin and quercetin did not inhibit neutrophil adhesion, (ii) quercetin inhibited degranulation, (iii) both inhibited myeloperoxidase activity (MPO), as well as (iv) both Inhibit the release of NETs in the absence of cell death. Molecular docking analyzes suggest that such events may be related to the generation of quercetin/MPO and rutin/elastase complexes
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Caruso, Ícaro Putinhon [UNESP]. « Estudo da interação entre flavonóides e a albumina do soro humano ». Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/87502.

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Made available in DSpace on 2014-06-11T19:22:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-06-21Bitstream added on 2014-06-13T18:49:51Z : No. of bitstreams: 1 caruso_ip_me_sjrp.pdf: 554320 bytes, checksum: da36f99ee0291c4e6b0bfd47dba308c0 (MD5)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Os flavonóides são uma grande classe de polifenóis ocorrendo de forma natural amplamente distribuídos nas plantas, essas moléculas exibem algumas atividades farmacológicas importantes como anti-inflamatória, antioxidante, anticancerígena e antibacteriana. A interação entre os flavonóides Rutina (Ru) e Guaijaverina (Gua) e a Albumina do Soro Humano (HSA) em pH 7,0 fisiológico foi investigado usando a técnica de espectroscopia de fluorescência de estado estacionário, cálculo ab initio e de modelagem molecular. A partir da supressão de fluorescência da HSA pelos flavonóides, a constante de supressão de Stern-Volmer ( SVK ) e sua forma modificada ( aK ) foram calculadas em 298, 303 e 308 K, como também os parâmetros termodinâmicos correspondentes H , G e S , para cada flavonóide. A análise do equilíbrio de ligação foi utilizada para determinar os valores do número de sítios de ligação ( n ) e a constante de ligação ( bK ) para a Rutina e a Guaijaverina em 298, 303 e 308 K. A distância média entre o doador (HSA-214Trp ) e o aceitador (Ru e Gua) foi estimada de acordo com a teoria de transferência de energia ressonante fluorescente. A otimização geométrica dos flavonóides Rutina e Guaijaverina foi realizada nos seus estados fundamentais usando o funcional DFT/B3LYP ab initio com um conjunto de bases 6-31G(d,p) utilizado nos cálculos. O cálculo de modelagem molecular indica que os flavonóides se localizam no sítio I da HSA, dentro do bolso hidrofóbico do subdomínio IIA. Os resultados teóricos obtidos pela modelagem molecular corroboram com os dados de espectroscopia de fluorescência
Flavonoids are a large class of naturally occurring polyphenols widely distributed in plants, these molecules exhibit some important pharmacological activities like anti-inflammatory, antioxidant, anticancer, and antibacterial. The interaction between Rutina and Guaijaverin flavonoids and Human Serum Albumin (HSA) at physiological pH 7.0 was investigated by using the technique of fluorescence spectroscopy, ab initio and molecular modeling calculation. From the fluorescence quenching of the HSA by flavonoids, the Stern-Volmer quenching constant ( SVK ) and its modified form ( aK ) were calculated at 298 , 303 and K308 , as well as the corresponding thermodynamic parameters H , G and S , for each flavonoid. Analysis of binding equilibria was utilized to determine the number of binding sites ( n ) and binding constants ( bK ) values for Rutin and Guaijaverin at 298 , 303 and K308 . The average distance between donor (HSA-214Trp ) e acceptor (Ru and Gua) was estimated according to the theory of fluorescence resonance energy transfer. The geometry optimization of Rutin and Guaijaverin flavonoids was performed in its ground state by using ab initio DFT/B3LYP functional with a 6-31G(d,p) basis set applied in calculations. Molecular modeling calculation indicated that the flavonoids are located in site I of HSA, within the hydrophobic pocket of the subdomain IIA. The theoretical results obtained by molecular modeling are corroborated by the fluorescence spectroscopy data

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Coqueiro, Aline. « Fracionamento bioguiado para selação de substâncias antioxidante, antimalárica e antibiótica potenciais nas espécies Kielmeyera variabilis (Clusiaceae) e Brosimum Glaziovii (Moraceae) / ». Araraquara : [s.n.], 2010. http://hdl.handle.net/11449/105815.

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Orientador: Vanderlan da Silva Bolzani
Banca: Marcia Nasser Lopes
Banca: José Angelo Slveira Zuanazzi
Banca: Horácio Adolfo Heinzen Gozález
Resumo: Os testes biológicos realizados por pesquisadores colaboradores do NuBBE para as espécies selecionadas para este estudo Brosimum glaziovii e Kielmeyera variabilis indicaram K. variabilis como uma importante fonte de metabólitos especiais bioativos. O fracionamento bioguiado da fração AcOEt dos galhos de K. variabilis para isolamento de substâncias com potencial antimalárico foi realizado via teste químico com -hematina e in vitro com Plasmodium falciparum, levando a identificação das xantonas oxigenadas 3,6-diidroxi-1,4,8-trimetoxixantona, 3,5-diidroxi-4-metoxixantona, 3,4-diidroxi-6,8-dimetoxixantona, 3,4-diidroxi-2-metoxixantona, 5-hidroxi-1,3- dimetoxixantona, 2,3-dimetoxi-4-hidroxixantona, 3-hidroxi-2-metoxixantona e 2-hidroxi- 1-metoxi-xantona e o xantonolignóide kielcorina. Dentre as substâncias isoladas, o xatonolignóide kielcorina foi considerado ativo quando comparado ao padrão cloroquina. A avaliação do potencial tripanocida também foi realizada para as xantonas isoladas e dentre estas, a 3,4-diidroxi-2-metoxixantona foi a mais ativa, principalmente para a cepa resistente ao benzonidazol (cepa Bolívia). Na fração EHFB das folhas de B. glaziovii foi observado o potencial antichagásico desta espécie. Os resultados observados para os ensaios antioxidantes levaram ao isolamento dos flavonóides quercitrina, podocarpusflavona A e da mistura de quercetina-3-Oglicosídeo e quercetina-3-O-galactosídeo, evidenciando a importância dos grupos catecólicos na potencialização da ação antioxidante. O estudo bioguiado pela atividade antimicrobiana com seis cepas de Staphylococcus aureus resistentes à meticilina culminou no isolamento de um derivado prenilado do floroglucinol (HGK-1) o qual demonstrou ser responsável pela potente atividade demonstrada pela fração hexânica dos galhos de K. variabilis. As xantonas isoladas tiveram seu potencial antimicrobiano... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: Several biological activities have been carried out by NuBBE's collaborators aiming the identification of active extracts from plant species, and Brosimum glaziovii and Kielmeyera variables showed to be important sources of bioactive secondary metabolites. Bio-guided fractionation of the EtOAc bioactive fraction of the branches of K. variabilis by using of the chemical test -hematin, and in vitro by using of Plasmodium falciparum, led to the isolation and identification of oxygenated xanthones 3,6-dihydroxy-1,4,8-trimethoxyxanthone, 3,5-dihydroxy-4-methoxyxanthone, 3,4- dihydroxy-6,8-dimethoxyxanthone, 3,4-dihydroxy-2-methoxyxanthone, 1,3-dimethoxy- 5-hydroxyxanthone, 2,3-dimethoxy-4-hydroxyxantona, 3-hydroxy-2-methoxyxanthone and 2-hydroxy-1-methoxyxanthone and xantonolignoid kielcorin. Among the compounds isolated, the xatonolignoid keilcorine indicated activity when compared to the standard chloroquine. The assessment of potential trypanocidal was also a part of this work and among the isolated xanthones, 3,4-dihydroxy-2-methoxyxanthone showed to be the most active, especially against the resistant strain to benzonidazole (Bolivia strain). In hexane fraction of leaves from B. glaziovii was noted antichagasic potencial for this specie. The antioxidant test used in this study led to the isolation of several flavonoids with antioxidant activity: quercitrin, podocarpusflavone A and the mixture of quercetin-3-O-glucoside and quercetin-3-O-galactoside, showing the importance of catechol group for the potentiating of antioxidant activity. The bio-guided antimicrobial activity using six strains of methicillin-resistant Staphylococcus aureus resulted in the isolation of the prenylated phloroglucinol derivative (HGK-1), which proved to be responsible for the potent activity exhibited by the hexane extract of the branches of K. variabilis. The xanthones isolated were evaluated... (Complete abstract click electronic access below)
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Lisseter, S. G. « Studies of phenolic flavonoids ». Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355739.

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Noroozi, Mostafa. « Antioxidant effects of flavonoids ». Thesis, University of Glasgow, 1998. http://theses.gla.ac.uk/5901/.

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Flavonoids are polyphenolic compounds whose main dietary source are fruits and vegetables. Epidemiological evidence has suggested that dietary flavonoids may protect against heart disease but biological effects have not hitherto been demonstrated directly in humans and there was no consistent evidence about the absorption of flavonoids. The studies performed for this thesis aimed to test antioxidant properties of flavonoids using an in vitro system, ex vivo tests on human tissue (lymphocytes) and in a dietary intervention. The main conclusions of this thesis are: 1. There is a potent antioxidant action of dietary flavonoids demonstrated by the comet assay, of potential importance in protection against cardiovascular disease and cancer. 2. The antioxidant capacities of most major dietary flavonoids are greater than vitamin C. 3. Results from the comet assay and TEAC show reasonable agreement in ranking. 4. Antioxidant activities of free flavonoids are more than the conjugated flavonoids. 5. There was a strong positive correlation between the number of hydroxyl groups of flavonoids and the antioxidant activity. 6. Dietary flavonoids are absorbed and the fasting plasma concentration can be increased 12 fold by a simple and palatable food supplement. 7. Supplementation with onions, tomato ketchup and tea led to protection of lymphocytes against free radical damage (H2O2), a biological effect of potential medical importance possibly attributable to the absorption of dietary flavonoids. 8. Dietary flavonoids intake (and specifically quercetin) can be estimated with reasonable accuracy from 24 hour urinary flavonoid excretion or fasting plasma concentration. 9. The range of dietary flavonoid consumption in ten NIDDM patients was estimated at 20-80 mg/day from their normal diets. On the basis of results in this thesis, dietary difference within this range would influence tissue antioxidant status.

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Kavuru, Padmini. « Crystal engineering of flavonoids ». [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002463.

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Alalwan, Tariq Abdulkarim Ebrahim. « Absorption of Dietary Flavonoids ». Thesis, University of Leeds, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491922.

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Flavonoids represent a major class of plant polyphenols that are distributed ubiquitously in the human diet. Interest in the possible health-promoting effects of flavonoids has increased due to their various bioactive properties, as demonstrated in several in vitro and in vivo studies. Knowledge about flavonoid absorption and bioavailability is essential in order to fully understand their potential health benefits. This thesis was concerned with the uptake and absorption of dietary flavonoids in humans, with an emphasis on the effect of the chemical form of the flavonoid (as a product of processing) and the effect of food matrix. The first study investigated the flavonol content in different varieties of commerciallygrown tomatoes and widely consumed tomato-based food products. It was shown that the levels of rutin varied considerably between different cultivars and food-based products, with the highest levels found in cherry tomatoes. Furthermore, cellulase -Blf h-=-y_d_ro---'l~~is_of rut~~_:v.~~_ shown to be a viable alternative for the release ~f queLc~~~~__ aglycone. The second study was aimed to investigate the absorption and bioavailability of dietary quercetin glycosides and its aglycone from a food-based system (non-supplement) in humans by implementing urinary time-course analysis. Ingested quercetin glycosides resulted in an observed earlier appearance of quercetin conjugates in urine then when quercetin aglycone was ingested (1 h compared to 2 h). Significantly more quercetin was absorbed than the aglycone when present in a similar onion-based food matrix system (1.8% compared to 1.3%). Finally, a second human study was carried out to investigate the effect of dietary fat, 8.3% (w/w), on the bioavailability of quercetin present in onion-based foods as either quercetin glycosides or its aglycone. Absorption of quercetin in its glycosidic form was shown to be significantly higher than the aglycone form when co-ingested with fat (2.8% compared to 1.7%). The ingestion of quercetin with fat, compared with the study without fat, enhanced the bioavailability of quercetin glycosides and its aglycone by about 50 and 23%, respectively, which was significant for the quercetin glycoside meal only.

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Uliana, Carolina Venturini. « Estudos da lesão ao DNA por corantes têxteis e da capacidade protetora de flavonóides empregando biossensor eletroquímico / Carolina Venturini Uliana. - ». Araraquara, 2013. http://hdl.handle.net/11449/105701.

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Orientador: Hideko Yamanaka
Banca: Maria Valnice Boldrin
Banca: Silvia Helena Pires Serrano
Banca: Ronaldo Censi Faria
Banca: Paulo Roberto Brasil de Oliveira Marques
Resumo: A molécula do DNA pode ser modificada por substâncias eletrofílicas, tanto de origem exógena quanto endógena. As lesões geradas podem ser mutagênicas e contribuir para o processo de carcinogênese. Assim, desvios significativos da estrutura da dupla hélice desempenham um papel importante no metabolismo do DNA. Um biossensor voltamétrico baseado na imobilização de DNA de fita dupla (dsDNA) sobre eletrodos descartáveis foi desenvolvido para aplicação nos estudos de interação entre corantes têxteis e a molécula do DNA, na ausência e na presença de flavonóides em solução. Os eletrodos modificados foram colocados em contato com soluções de corantes têxteis da classe dos dispersos, o Disperso Orange 1 (DO1) e o Disperso Red 1 (DR1), e seus produtos de eletrólise por oxidação e por redução. A variação dos sinais de oxidação das bases guanina e adenina presentes no dsDNA imobilizado, obtidos antes e após cada interação, foi utilizada como parâmetro de análise dos resultados. O tempo para que a interação DNA:corante ocorresse foi avaliado utilizando o biossensor e estabeleceu-se 180 s. A concentração dos corantes foi analisada na faixa de 1,0 x 10-8 a 1,0 x 10-4 mol L-1, sendo que a variação do sinal voltamétrico das bases foi mais intensa para DR1 (sinais da guanina e adenina decresceram 48% e 51% do seu valor original, respectivamente), enquanto que na presença de DO1, as intensidades de corrente da guanina e adenina diminuíram 30% e 10% de seu valor original, respectivamente, quando comparada a mesma concentração dos corantes de 1,0 x 10-6 mol L-1. Além da diminuição da intensidade de corrente das bases guanina e adenina, o aparecimento de novos picos e deslocamentos do potencial de pico das bases foram observados após as interações com produtos de eletrólises. Estudos de interação também... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: DNA molecule may be modified by electrophilic substances, either from endogenous or exogenous origin. Lesions generated may be mutagenic and contribute to the process of carcinogenesis. In this way, significant deviations on the double helix structure play an important role in the DNA metabolism. A biosensor based on double-stranded DNA (dsDNA) immobilization on disposable electrodes has been developed for application in interaction studies between textile dyes and DNA molecule in the absence and presence of flavonoids in solution. The modified electrodes were placed in solutions of disperse textile dyes, Disperse Orange 1 (DO1) and Disperse Red 1 (DR1), and their products of electrolyses by oxidation and reduction. The variation of the oxidation signals of guanine and adenine bases of the immobilized dsDNA, obtained before and after each interaction, was used as a parameter for analyzing the results. The time for DNA:dye interaction was evaluated using the biosensor and 180 s was established. The concentration of dyes was analyzed in the range from 1.0 x 10-8 to 1.0 x 10-4 mol L-1, and the bases voltammetric signal variation was more intense for DR1 (signals of guanine and adenine decreased 48% and 51% of its original value, respectively), whereas in the presence of DO1, the current intensities of guanine and adenine decreased by 30% and 10% of its original value, respectively, when compared the same dyes concentration of 1.0 x 10-6 mol L-1. Besides adenine and guanine current intensities decrease, the appearance of new peaks and peaks potential shifts were also observed after interactions with electrolysis products. Interaction studies were also performed by means of UV-Vis spectrophotometry in aqueous phase showed different effects of hypochromism and hiperchromism of DNA band after interactions... (Complete abstract click electronic access below)
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Livres sur le sujet "Flavonoids Flavonoids"

Harborne, J. B., dir. The Flavonoids. Boston, MA : Springer US, 1994. http://dx.doi.org/10.1007/978-1-4899-2911-2.

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Harborne, J. B., dir. The Flavonoids. Boston, MA : Springer US, 1988. http://dx.doi.org/10.1007/978-1-4899-2913-6.

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Introduction to flavonoids. Amsterdam : Harwood Academic Publishers, 1998.

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Buslig, Béla S., et John A. Manthey, dir. Flavonoids in Cell Function. Boston, MA : Springer US, 2002. http://dx.doi.org/10.1007/978-1-4757-5235-9.

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Grotewold, Erich, dir. The Science of Flavonoids. New York, NY : Springer New York, 2006. http://dx.doi.org/10.1007/978-0-387-28822-2.

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Grotewold, Erich, dir. The Science of Flavonoids. New York : Springer-Verlag, 2006. http://dx.doi.org/10.1007/0-387-28822-8.

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Swanson, Hollie. Flavonoids, inflammation and cancer. New Jersey : World Scientific, 2016.

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Manthey, John A., et Béla S. Buslig, dir. Flavonoids in the Living System. Boston, MA : Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5335-9.

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Hungarian Bioflavonoid Symposium (7th 1985 Szeged). Flavonoids and bioflavonoids, 1985 : Proceedings of the 7th Hungarian Bioflavonoid Symposium, Szeged, Hungary, May 16-18, 1985. Amsterdam : Elsevier, 1986.

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Murphy, Rosemary A. Studies in the synthesis of azaflavanoids and azaaurones. Dublin : University College Dublin, 1997.

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Chapitres de livres sur le sujet "Flavonoids Flavonoids"

Antunes-Ricardo, Marilena, et Janet Alejandra Gutiérrez-Uribe. « Flavonoids ». Dans Phenolic Compounds in Food, 173–84. Boca Raton : CRC Press, Taylor & Francis Group, 2018. : CRC Press, 2018. http://dx.doi.org/10.1201/9781315120157-10.

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Seigler, David S. « Flavonoids ». Dans Plant Secondary Metabolism, 151–92. Boston, MA : Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-4913-0_11.

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Schwab, Manfred. « Flavonoids ». Dans Encyclopedia of Cancer, 1. Berlin, Heidelberg : Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_2204-2.

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Hodek, Petr. « Flavonoids ». Dans Metabolism of Drugs and Other Xenobiotics, 543–82. Weinheim, Germany : Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527630905.ch20.

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Harborne, J. B. « Flavonoids ». Dans Natural Products of Woody Plants, 533–70. Berlin, Heidelberg : Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74075-6_16.

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Geiger, Hans. « Miscellaneous flavonoids ». Dans The Flavonoids, 389–97. Boston, MA : Springer US, 1988. http://dx.doi.org/10.1007/978-1-4899-2913-6_10.

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Strack, Dieter, et Victor Wray. « The anthocyanins ». Dans The Flavonoids, 1–22. Boston, MA : Springer US, 1993. http://dx.doi.org/10.1007/978-1-4899-2911-2_1.

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Markham, K. R., et H. Geiger. « 1H nuclear magnetic resonance spectroscopy of flavonoids and their glycosides in hexadeuterodimethylsulfoxide ». Dans The Flavonoids, 441–97. Boston, MA : Springer US, 1993. http://dx.doi.org/10.1007/978-1-4899-2911-2_10.

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Heller, Werner, et Gert Forkmann. « Biosynthesis of flavonoids ». Dans The Flavonoids, 499–535. Boston, MA : Springer US, 1993. http://dx.doi.org/10.1007/978-1-4899-2911-2_11.

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Forkmann, Gert. « Genetics of flavonoids ». Dans The Flavonoids, 537–64. Boston, MA : Springer US, 1993. http://dx.doi.org/10.1007/978-1-4899-2911-2_12.

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Actes de conférences sur le sujet "Flavonoids Flavonoids"

Almughraby, E., M. I. Kalimullin, A. A. Mostyakova et O. A. Timofeeva. « VARIETY SPECIFICITY OF PHYTOCHEMICAL COMPOSITION B. OLERACEA L. VAR. ACEPHALA ». Dans STATE AND DEVELOPMENT PROSPECTS OF AGRIBUSINESS. DSTU-PRINT, 2020. http://dx.doi.org/10.23947/interagro.2020.1.340-343.

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Purpose of work - Comparative analysis the content of phenolic compounds, flavonoids, carotenoids, vitamin C, protein and sugars in different varieties of cabbage kale (B. oleracea L. convar. Acephala). As an object of study, we used 2 varieties of cabbage kale - Premier cabbage, Dwarf Blue Curled with green leaves, Redbor with red leaves and Scarlet with purple. It was shown that the content of phenolic compounds and flavonoids was significantly higher in red varieties, compared with green. The content of carotenoids was higher in green varieties. The highest content of flavonoid was found in the variety «Scarlet» and vitamin C in the variety «Redbor». However, the amount of proteins and sugars, there were no significant differences between the varieties.

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Rodríguez-Ramírez, Juan, Irene Chaparro-Hernández, Lilia L. Méndez-Lagunas et Luis Gerardo Barriada-Bernal. « Effect of spray drying conditions on antioxidants activity, flavonoids and total phenolic compounds of stevia rebaudiana ». Dans 21st International Drying Symposium. Valencia : Universitat Politècnica València, 2018. http://dx.doi.org/10.4995/ids2018.2018.7518.

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In this work the spray drying of the fresh stevia leaves aqueous extract without encapsulating agents was carried out. The effect of the inlet air temperature (160-200 ºC) and the feed flow rate (2-3 kg/h) on the total phenolic content, the total flavonoid content and the antioxidant capacity were evaluated using Folin-Ciocalteau, aluminum chloride and DPPH methods respectively. The inlet air temperature had a significant effect on all parameters evaluated that showed a decrease when increasing the inlet air temperature, the feed flow rate had a significant effect on total flavonoids content and the antioxidant capacity, by increasing the feed flow rate the inhibition of the DPPH radical decreased and the total flavonoid content increased. The treatment at 160 ºC and 3 kg/h retained highest total flavonoid content and the antioxidant capacity. Keywords: Phenolic compounds, stevia, spray drying, antioxidant capacity

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Subbotina, E. A. « FLAVONOIDS IN BEE PRODUCTS ». Dans Современные проблемы пчеловодства и апитерапии. Рыбное : Федеральное государственное бюджетное научное учреждение "Федеральный научный центр пчеловодства", 2021. http://dx.doi.org/10.51759/pchel_api_2021_463.

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Syafni, N., AM Klemd, JK Reinhardt, O. Danton, C. Gründemann et M. Hamburger. « Immunosuppressant flavonoids from Scutellaria baicalensis ». Dans 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399888.

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Xu, Ying, Qichang Dai, Zongze Luan, Zheng Xiang, Jian Wu et Yuling Fan. « Three Flavonoids from Cycas Revoluta ». Dans The 2nd International Conference on Intelligent Systems and Image Processing 2014. The Institute of Industrial Applications Engineers, 2014. http://dx.doi.org/10.12792/icisip2014.054.

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Huang, X. L., M. C. Peng, J. X. Liu, Y. Lei, X. J. Yang et Z. H. Wu. « Hot air drying characteristics and nutrients of apricot armeniaca vulgaris lam pretreated with Radio Frequency(RF) ». Dans 21st International Drying Symposium. Valencia : Universitat Politècnica València, 2018. http://dx.doi.org/10.4995/ids2018.2018.7524.

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Apricot pretreated with RF and then dried with convective hot air at 65℃, 3.0m/s in this research. RF pretreatment time of 20, 30, 40 and 50min were chosen. Results showed that, there is only falling rate period during apricot hot air drying, and the drying rate of apricot is improved significantly; Herdenson and Pabis model is suitable for apricot hot air drying; retentions of flavonoids, polyphenols and Vc in dried apricot were higher than those of fresh apricot; when RF treating time was chosen 30mins, nutrients retentions of Vc, flavonoid and polyphenols were 0.9543mg/100g, 5.4089mg/100g and 7.3382mg/100g, separately. Keywords: apricot fruit, hot air drying, drying rate, nutrients, radio frequency

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Alpatova, N. V., I. A. Dubrovskaya et M. V. Slobodyanik. « Methods for the determination of flavonoids in plant raw materials and products of their processing ». Dans CURRENT STATE, PROBLEMS AND PROSPECTS OF THE DEVELOPMENT OF AGRARIAN SCIENCE. Federal State Budget Scientific Institution “Research Institute of Agriculture of Crimea”, 2020. http://dx.doi.org/10.33952/2542-0720-2020-5-9-10-125-1.

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Flavonoids are an important component of plant materials; they have medicinal and biologically active properties. To use them as medicines, it is necessary to determine their qualitative and quantitative composition. The aim of this work is a comparative analysis of the identification and metrological characteristics of methods for the determination of flavonoids in plant raw materials and products of their processing. The paper presents a brief literature review of the main methods for the study of flavonoids. Certified and advanced techniques, such as NMR and mass spectrometry, have been discussed.

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Moradi Yeganmahale, Sina, Farahnaz Mohammadi Arab Abadi, Mohammad Hossin Abdoli et Mohammed Hosseini Goke. « Flavonoids Effects on Breast Cancer Tumors ». Dans International e-Conference on Cancer Research 2019. European High-tech and Emerging Research Association, 2019. http://dx.doi.org/10.28991/iccr-2019-005.

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Kostikova, V. A., et T. N. Veklich. « Content of flavonoids and phenolcarboxylic acids in leaves and inflorescences of Spiraea salicifolia L. (Rosaceae) ». Dans Problems of studying the vegetation cover of Siberia. TSU Press, 2020. http://dx.doi.org/10.17223/978-5-94621-927-3-2020-20.

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Comparative analysis of the content of the main groups of phenolic compounds (flavonoids and phenolic acids) was performed for the overground part of Spiraea salicifolia L. from natural habitats in Siberia and the Russian Far East. Populations of plants with the highest content of phenolic compounds were determined to reveal the potential of their use. It was found that the content of phenolcarboxylic acids in leaves (3,59–7,69 %) is higher than that in inflorescences (2,24–5,52 %), regardless of habitat. The distribution of flavonoids between leaves and inflorescences of S. salicifolia is ambiguous. The content of flavonoids ranges from 1,27 % to 5,48 % in leaves, and from 2,34 % to 6,26 % in inflorescences. The highest content of flavonoids and phenolcarboxylic acids was found in plants from Amur region, the Republic of Yakutia, the Republic of Buryatia and the Primorsky Territory. The content of the investigated substances is not high in samples of S. salicifolia from Irkutsk region, Sakhalin region, Khabarovsk region and Magadan region.

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Tkachova, E. N., L. V. Kalinichenko et E. L. Malankina. « Intrasspecific variability in raw material biochemical composition of Hyssopus officinalis L. » Dans Растениеводство и луговодство. Тимирязевская сельскохозяйственная академия, 2020. http://dx.doi.org/10.26897/978-5-9675-1762-4-2020-174.

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It was studied the content of essential oil, flavonoids, rosmarinic acid in raw materials of 14 varieties of medicinal hyssop from different origin. The content of essential oil ranged within 0.11-0.55% in fresh raw materials, rosmarinic acid in the range of 0.49-0.80%, and flavonoids - 0.68-1.65%.

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Rapports d'organisations sur le sujet "Flavonoids Flavonoids"

Henning, Susanne M. Flavonoids and DNA Repair in Prostate Cancer. Fort Belvoir, VA : Defense Technical Information Center, décembre 2004. http://dx.doi.org/10.21236/ada434003.

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Henning, Susanne. Flavonoids and DNA Repair in Prostate Cancer. Fort Belvoir, VA : Defense Technical Information Center, décembre 2005. http://dx.doi.org/10.21236/ada448584.

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Busby, Ryan, David Ringelberg et Carina Jung. Flavonoids Differentially Influence Rhizosphere Bacterial Communities from Native and Introduced Lespedeza Roots. Engineer Research and Development Center (U.S.), août 2018. http://dx.doi.org/10.21079/11681/28063.

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Yao, Jia, Xianzhe Wang, Jia Zhao, Zhaojun Yang, Yuping Lin, Lu Sun, Yuan Zhang, Qiyun Lu et Guanjie Fan. Flavonoids for viral acute respiratory tract infections : a systematic review and meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, août 2021. http://dx.doi.org/10.37766/inplasy2021.8.0107.

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Carraway, Robert E., et Paul Dobner. Prostate Cancer Cell Growth : Stimulatory Role of Neurotensin and Mechanism of Inhibition by Flavonoids as Related to Protein Kinase C. Fort Belvoir, VA : Defense Technical Information Center, janvier 2009. http://dx.doi.org/10.21236/ada499617.

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Gutiérrez Merino, Carlos. Flavonoides antioxidantes y salud : ¿una quimera o una lotería ? Sociedad Española de Bioquímica y Biología Molecular (SEBBM), février 2014. http://dx.doi.org/10.18567/sebbmdiv_rpc.2014.02.1.

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Kozhuharova, Asya, Marina Stanilova, Milena Nikolva, Rumen Denev et Strahil Berkov. Glycyrrhizin and Flavonoid Contents of the Bulgarian Glycyrrhiza glabra Populations. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, juillet 2021. http://dx.doi.org/10.7546/crabs.2021.07.05.

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Harding, Scott, A, Chung-jui Tsai et Lindroth, Richard, L. A genomics investigation of partitioning into and among flavonoid-derived condensed tannins for carbon sequestration in Populus. Office of Scientific and Technical Information (OSTI), mars 2013. http://dx.doi.org/10.2172/1069258.

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