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Articles de revues sur le sujet « Functional delivery »

Auteur : Grafiati

Publié le 29 mars 2025

Mis à jour le 31 juillet 2025

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1

Kim, Raeyeong, and Jong Hyun Kim. "Engineered Extracellular Vesicles with Compound-Induced Cargo Delivery to Solid Tumors." International Journal of Molecular Sciences 24, no. 11 (2023): 9368. http://dx.doi.org/10.3390/ijms24119368.

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Efficient delivery of functional factors into target cells remains challenging. Although extracellular vesicles (EVs) are considered to be potential therapeutic delivery vehicles, a variety of efficient therapeutic delivery tools are still needed for cancer cells. Herein, we demonstrated a promising method to deliver EVs to refractory cancer cells via a small molecule-induced trafficking system. We generated an inducible interaction system between the FKBP12-rapamycin-binding protein (FRB) domain and FK506 binding protein (FKBP) to deliver specific cargo to EVs. CD9, an abundant protein in EVs

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Gibbons, Jeremy. "Free delivery (functional pearl)." ACM SIGPLAN Notices 51, no. 12 (2018): 45–50. http://dx.doi.org/10.1145/3241625.2976005.

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Nakazato, Yugo, and Joji M. Otaki. "Protein Delivery to Insect Epithelial Cells In Vivo: Potential Application to Functional Molecular Analysis of Proteins in Butterfly Wing Development." BioTech 12, no. 2 (2023): 28. http://dx.doi.org/10.3390/biotech12020028.

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Protein delivery to cells in vivo has great potential for the functional analysis of proteins in nonmodel organisms. In this study, using the butterfly wing system, we investigated a method of protein delivery to insect epithelial cells that allows for easy access, treatment, and observation in real time in vivo. Topical and systemic applications (called the sandwich and injection methods, respectively) were tested. In both methods, green/orange fluorescent proteins (GFP/OFP) were naturally incorporated into intracellular vesicles and occasionally into the cytosol from the apical surface witho

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Kanada, Masamitsu, Michael H. Bachmann, Jonathan W. Hardy, et al. "Differential fates of biomolecules delivered to target cells via extracellular vesicles." Proceedings of the National Academy of Sciences 112, no. 12 (2015): E1433—E1442. http://dx.doi.org/10.1073/pnas.1418401112.

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Extracellular vesicles (EVs), specifically exosomes and microvesicles (MVs), are presumed to play key roles in cell–cell communication via transfer of biomolecules between cells. The biogenesis of these two types of EVs differs as they originate from either the endosomal (exosomes) or plasma (MVs) membranes. To elucidate the primary means through which EVs mediate intercellular communication, we characterized their ability to encapsulate and deliver different types of macromolecules from transiently transfected cells. Both EV types encapsulated reporter proteins and mRNA but only MVs transferr

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Barthélémy, Philippe, and Michel Camplo. "Functional Amphiphiles for Gene Delivery." MRS Bulletin 30, no. 9 (2005): 647–53. http://dx.doi.org/10.1557/mrs2005.191.

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AbstractThe design of safe and efficient gene transfer vectors remains one of the key challenges in gene therapy. Despite their remarkable transfection efficiency, viral vectors suffer from known safety issues. Consequently, significant research activity has been undertaken to develop nonviral approaches to gene transfer during the last decade. Numerous academic and industrial research groups are investigating synthetic cationic vectors, such as cationic amphiphiles, with the objective of increasing the gene transfection activity. Within this area, the development of functional synthetic vecto

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Tai, Wanyi, and Xiaohu Gao. "Functional peptides for siRNA delivery." Advanced Drug Delivery Reviews 110-111 (February 2017): 157–68. http://dx.doi.org/10.1016/j.addr.2016.08.004.

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Sago, Cory D., Melissa P. Lokugamage, Kalina Paunovska, et al. "High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing." Proceedings of the National Academy of Sciences 115, no. 42 (2018): E9944—E9952. http://dx.doi.org/10.1073/pnas.1811276115.

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Dysfunctional endothelium causes more disease than any other cell type. Systemically administered RNA delivery to nonliver tissues remains challenging, in large part because there is no high-throughput method to identify nanoparticles that deliver functional mRNA to cells in vivo. Here we report a system capable of simultaneously quantifying how >100 lipid nanoparticles (LNPs) deliver mRNA that is translated into functional protein. Using this system (named FIND), we measured how >250 LNPs delivered mRNA to multiple cell types in vivo and identified 7C2 and 7C3, two LNPs that efficiently

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Stone, Shane, Tatjana Heinrich, Suzy Juraja та ін. "β-Lactamase Tools for Establishing Cell Internalization and Cytosolic Delivery of Cell Penetrating Peptides". Biomolecules 8, № 3 (2018): 51. http://dx.doi.org/10.3390/biom8030051.

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The ability of cell penetrating peptides (CPPs) to deliver biologically relevant cargos into cells is becoming more important as targets in the intracellular space continue to be explored. We have developed two assays based on CPP-dependent, intracellular delivery of TEM-1 β-lactamase enzyme, a functional biological molecule comparable in size to many protein therapeutics. The first assay focuses on the delivery of full-length β-lactamase to evaluate the internalization potential of a CPP sequence. The second assay uses a split-protein system where one component of β-lactamase is constitutivel

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Schwarz, Carsten, Claudio Procaccianti, Laura Costa, et al. "Differential Performance and Lung Deposition of Levofloxacin with Different Nebulisers Used in Cystic Fibrosis." International Journal of Molecular Sciences 23, no. 17 (2022): 9597. http://dx.doi.org/10.3390/ijms23179597.

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We compared the performance and levofloxacin (Quinsair) lung deposition of three nebulisers commonly used in CF (I-Neb Advance, eFlow rapid, and LC Plus) with the approved nebuliser Zirela. The delivered dose, delivery rate, and aerosol particle size distribution (APSD) for each device were determined using the methods described in the Pharmacopeia. High-resolution computed tomography scans obtained from seven adult patients with mild CF were used to generate computer-aided, three-dimensional models of their airway tree to assess lung deposition using functional respiratory imaging (FRI). The

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Arnold, Amy E., Laura J. Smith, Greg Beilhartz, et al. "Attenuated diphtheria toxin mediates siRNA delivery." Science Advances 6, no. 18 (2020): eaaz4848. http://dx.doi.org/10.1126/sciadv.aaz4848.

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Toxins efficiently deliver cargo to cells by binding to cell surface ligands, initiating endocytosis, and escaping the endolysosomal pathway into the cytoplasm. We took advantage of this delivery pathway by conjugating an attenuated diphtheria toxin to siRNA, thereby achieving gene downregulation in patient-derived glioblastoma cells. We delivered siRNA against integrin-β1 (ITGB1)—a gene that promotes invasion and metastasis—and siRNA against eukaryotic translation initiation factor 3 subunit b (eIF-3b)—a survival gene. We demonstrated mRNA downregulation of both genes and the corresponding fu

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Jun Loh, Xian, and Tung-Chun Lee. "Gene Delivery by Functional Inorganic Nanocarriers." Recent Patents on DNA & Gene Sequences 6, no. 2 (2012): 108–14. http://dx.doi.org/10.2174/187221512801327361.

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Qiao, Ruirui. "Functional Polymeric Nanoparticles for Drug Delivery." Current Pharmaceutical Design 28, no. 5 (2022): 339. http://dx.doi.org/10.2174/138161282805220111142951.

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Jeon, Gumhye, Seung Yun Yang, and Jin Kon Kim. "Functional nanoporous membranes for drug delivery." Journal of Materials Chemistry 22, no. 30 (2012): 14814. http://dx.doi.org/10.1039/c2jm32430j.

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Lian, Zheng, and Tianjiao Ji. "Functional peptide-based drug delivery systems." Journal of Materials Chemistry B 8, no. 31 (2020): 6517–29. http://dx.doi.org/10.1039/d0tb00713g.

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Paleos, Constantinos M., Leto-Aikaterini Tziveleka, Zili Sideratou, and Dimitris Tsiourvas. "Gene delivery using functional dendritic polymers." Expert Opinion on Drug Delivery 6, no. 1 (2009): 27–38. http://dx.doi.org/10.1517/17425240802607345.

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Qian, Zhuzhong, Sheng Zhang, Kangbin Yim, and Sanglu Lu. "Service Oriented Multimedia Delivery System in Pervasive Environments." JUCS - Journal of Universal Computer Science 17, no. (6) (2011): 961–80. https://doi.org/10.3217/jucs-017-06-0961.

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Service composition is an effective approach for large-scale multimedia delivery. In previous works, user requirement is represented as one fixed functional path which is composed of several functional components in a certain order. Actually, there may be several functional paths (deliver different quality level multimedia data, e.g., image pixel, frame rate) that can meet one request. And due to the diversity of devices and connections in pervasive environment, system should choose a suitable media quality delivery path in accordance with context, instead of one fixed functional path. This pa

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Heath, Nikki, Xabier Osteikoetxea, Taiana Mia de Oliveria, et al. "Endosomal escape enhancing compounds facilitate functional delivery of extracellular vesicle cargo." Nanomedicine 14, no. 21 (2019): 2799–814. http://dx.doi.org/10.2217/nnm-2019-0061.

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Aim: Extracellular vesicles (EVs) are desirable delivery vehicles for therapeutic cargoes. We aimed to load EVs with Cre recombinase protein and determine whether functional delivery to cells could be improved by using endosomal escape enhancing compounds. Materials & methods: Overexpressed CreFRB protein was actively loaded into EVs by rapalog-induced dimerization to CD81FKBP, or passively loaded by overexpression in the absence of rapalog. Functional delivery of CreFRB was analysed using a HEK293 Cre reporter cell line in the absence and presence of endosomal escape enhancing compounds.

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Venkata, Sai Dheeraj Munjulury, Dornadula Girirajasekhar, and Narasimha Gunturu Lakshmi. "Nanofibrous Biomaterial based Carriers and their Recent Advances in Drug and Gene Delivery." Chemistry Research Journal 5, no. 6 (2020): 213–20. https://doi.org/10.5281/zenodo.13148588.

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<strong>Abstract </strong>Drug delivery by Nanofibrous biomaterials meets immense possibilities in the therapeutic area, anticipated to their structural and functional resemblance with biological Extracellular matrix (ECM).Broad spectrums of natural and polymeric materials are utilized in the fabrication of nanofibrous biomaterials. Therefore, this write-up presents considerable natural and synthetic biomaterials for the manufacturing of nanofibers with essential properties like biocompatibility and biodegradability. Various approaches with their merits and demerits in the production of nanofi

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Yuan, Ahu, Yiqiao Hu, and Xin Ming. "Dendrimer conjugates for light-activated delivery of antisense oligonucleotides." RSC Advances 5, no. 44 (2015): 35195–200. http://dx.doi.org/10.1039/c5ra04091d.

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PAMAM dendrimer conjugates are used to co-deliver oligonucleotides and photosensitizers to cancer cells. After photo-irradiation, substantial reporter eGFP expression is produced by functional delivery of a model oligonucleotide.

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Parke, Barbara, Richard D. Penn, Suzanne M. Savoy, and Daniel Corcos. "Functional Outcome after Delivery of Intrathecal Baclofen." Archives of Physical Medicine and Rehabilitation 70, no. 1 (1989): 30–32. http://dx.doi.org/10.1016/s0003-9993(21)01642-7.

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Pegtel, D. M., K. Cosmopoulos, D. A. Thorley-Lawson, et al. "Functional delivery of viral miRNAs via exosomes." Proceedings of the National Academy of Sciences 107, no. 14 (2010): 6328–33. http://dx.doi.org/10.1073/pnas.0914843107.

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Brodin, Jeffrey D., Anthony J. Sprangers, Janet R. McMillan, and Chad A. Mirkin. "DNA-Mediated Cellular Delivery of Functional Enzymes." Journal of the American Chemical Society 137, no. 47 (2015): 14838–41. http://dx.doi.org/10.1021/jacs.5b09711.

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Xing, Ruijun, Gang Liu, Qimeng Quan, et al. "Functional MnO nanoclusters for efficient siRNA delivery." Chemical Communications 47, no. 44 (2011): 12152. http://dx.doi.org/10.1039/c1cc15408g.

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Ye, Yuanfeng, Xincheng Mao, Jialing Xu, Jingyang Kong, and Xiaohong Hu. "Functional Graphene Oxide Nanocarriers for Drug Delivery." International Journal of Polymer Science 2019 (January 31, 2019): 1–7. http://dx.doi.org/10.1155/2019/8453493.

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The family of graphene has attracted increasing attention on account of their large specific surface area and good mechanical properties in the biomedical field. However, some characteristics like targeted delivery property and drug delivery capacity could not satisfy the need of a drug carrier. Herein, a graphene oxide (GO) nanocarrier was designed by modification of a folic acid (FA) derivative and a β-cyclodextrin (β-CD) derivative in order to improve two properties, respectively. In the first step, reactive or crosslinkable FA and aldehydic β-CD (β-CD-CHO) were designed and synthesized for

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Tezgel, A. Özgül, Paejonette Jacobs, Coralie M. Backlund, Janice C. Telfer, and Gregory N. Tew. "Synthetic Protein Mimics for Functional Protein Delivery." Biomacromolecules 18, no. 3 (2017): 819–25. http://dx.doi.org/10.1021/acs.biomac.6b01685.

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Constantinescu, Florin-Eugen. "Functional Biomaterials Drug Delivery and Biomedical Applications." STOMATOLOGY EDU JOURNAL 9, no. 3-4 (2022): 133. http://dx.doi.org/10.25241/stomaeduj.2022.9(3-4).bookreview.5.

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Feng, Yiming, and Youngsoo Lee. "Microfluidic assembly of food-grade delivery systems: Toward functional delivery structure design." Trends in Food Science & Technology 86 (April 2019): 465–78. http://dx.doi.org/10.1016/j.tifs.2019.02.054.

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Patil, Gao, Lin, et al. "The Development of Functional Non-Viral Vectors for Gene Delivery." International Journal of Molecular Sciences 20, no. 21 (2019): 5491. http://dx.doi.org/10.3390/ijms20215491.

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Gene therapy is manipulation in/of gene expression in specific cells/tissue to treat diseases. This manipulation is carried out by introducing exogenous nucleic acids, such as DNA or RNA, into the cell. Because of their negative charge and considerable larger size, the delivery of these molecules, in general, should be mediated by gene vectors. Non-viral vectors, as promising delivery systems, have received considerable attention due to their low cytotoxicity and non-immunogenicity. As research continued, more and more functional non-viral vectors have emerged. They not only have the ability t

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Ruan, Jinglin, and Volker Patzel. "Abstract P23: Mitochondrial Delivery of Functional Nucleic Acids for Targeting of Mitochondrial Dysfunction." Cancer Research 84, no. 8_Supplement (2024): P23. http://dx.doi.org/10.1158/1538-7445.fcs2023-p23.

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Abstract Mitochondria is the main power supply for cellular activity and a key player for the regulation of cellular metabolism, and they contain their own DNA. Critical proteins for mitochondrial functions are not only encoded by nuclear DNA (nDNA) but also by mitochondrial DNA (mtDNA). Abnormalities in mitochondrial functions could lead to diseases including neurodegeneration, diabetes, and cancer progression. The ability for a non-coding RNA (β2.7) of human cytomegalovirus (CMV) to localize to the host mitochondria revealed its potential to be used as a tool for mitochondria gene targeting.

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Booth, Michael J., Vanessa Restrepo Schild, Florence G. Downs, and Hagan Bayley. "Functional aqueous droplet networks." Molecular BioSystems 13, no. 9 (2017): 1658–91. http://dx.doi.org/10.1039/c7mb00192d.

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McKinlay, Colin J., Jessica R. Vargas, Timothy R. Blake, et al. "Charge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animals." Proceedings of the National Academy of Sciences 114, no. 4 (2017): E448—E456. http://dx.doi.org/10.1073/pnas.1614193114.

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Functional delivery of mRNA to tissues in the body is key to implementing fundamentally new and potentially transformative strategies for vaccination, protein replacement therapy, and genome editing, collectively affecting approaches for the prevention, detection, and treatment of disease. Broadly applicable tools for the efficient delivery of mRNA into cultured cells would advance many areas of research, and effective and safe in vivo mRNA delivery could fundamentally transform clinical practice. Here we report the step-economical synthesis and evaluation of a tunable and effective class of s

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Anitha, P., J. Bhargavi, G. Sravani, B. Aruna, and Ramkanth S. "RECENT PROGRESS OF DENDRIMERS IN DRUG DELIVERY FOR CANCER THERAPY." International Journal of Applied Pharmaceutics 10, no. 5 (2018): 34. http://dx.doi.org/10.22159/ijap.2018v10i5.27075.

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With the recent advances of nanotechnology, dendrimers are emerging as a highly attractive class of drug delivery vectors for cancer therapy. Dendrimers are multifunctional smart Nanocarriers to deliver one or more therapeutic agent safely and selectively to cancer cells. The high level of control over the synthesis of dendritic architecture makes dendrimers a nearly perfect (spherical) nanocarrier for site-specific drug delivery. The presence of functional groups in the dendrimers exterior also permits the addition of other moieties that can actively target certain diseases which are now wide

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Yu, Xueliang, Shuai Liu, Qiang Cheng, et al. "Hydrophobic Optimization of Functional Poly(TPAE-co-suberoyl chloride) for Extrahepatic mRNA Delivery following Intravenous Administration." Pharmaceutics 13, no. 11 (2021): 1914. http://dx.doi.org/10.3390/pharmaceutics13111914.

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Messenger RNA (mRNA) has generated great attention due to its broad potential therapeutic applications, including vaccines, protein replacement therapy, and immunotherapy. Compared to other nucleic acids (e.g., siRNA and pDNA), there are more opportunities to improve the delivery efficacy of mRNA through systematic optimization. In this report, we studied a high-throughput library of 1200 functional polyesters for systemic mRNA delivery. We focused on the chemical investigation of hydrophobic optimization as a method to adjust mRNA polyplex stability, diameter, pKa, and efficacy. Focusing on a

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Rezvani, Mohaddeseh, Narmin Ghani Zadeh Hesar, Ebrahim Mohammad Ali Nasab Firouzjah, and Hengameh Sheikh. "Comparing Functional Disability and Body Image Between Women With Normal Delivery and Cesarean Section." Scientific Journal of Rehabilitation Medicine 13, no. 03 (2024): 650–63. http://dx.doi.org/10.32598/sjrm.13.3.3156.

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Background and Aims During pregnancy, a woman’s body undergoes many changes, which can be studied from physiological and psychological aspects. The purpose of this research is to compare functional disability and body image after normal and cesarean delivery. Methods The current research is of a comparative causal type. In this study, 114 non-athlete women who gave birth in Urmia City, Iran, were selected voluntarily and availably within one month after delivery. Of these, 58 had a normal delivery and 56 a cesarean delivery. Back functional disability was evaluated by the Oswestry disability i

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Sellers, Drew L., Jamie M. Bergen, Russell N. Johnson, et al. "Targeted axonal import (TAxI) peptide delivers functional proteins into spinal cord motor neurons after peripheral administration." Proceedings of the National Academy of Sciences 113, no. 9 (2016): 2514–19. http://dx.doi.org/10.1073/pnas.1515526113.

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A significant unmet need in treating neurodegenerative disease is effective methods for delivery of biologic drugs, such as peptides, proteins, or nucleic acids into the central nervous system (CNS). To date, there are no operative technologies for the delivery of macromolecular drugs to the CNS via peripheral administration routes. Using an in vivo phage-display screen, we identify a peptide, targeted axonal import (TAxI), that enriched recombinant bacteriophage accumulation and delivered protein cargo into spinal cord motor neurons after intramuscular injection. In animals with transected pe

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Vikas, Dhawan1 Poornima Kala*2. "Niosomes A Novel Drug Delivery System." International Journal in Pharmaceutical Sciences 2, no. 3 (2024): 767–72. https://doi.org/10.5281/zenodo.10850135.

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Niosomes are novel multilamellar or unilamellar vesicles, formed by a hydrating mixture of cholesterol and nonionic surfactants.Niosomes are a type of vesicular nanocarrier exploited for enhancing the therapeutic efficacy of various drugs in clinical practice. Niosomes comprise a bilayer hydrophobic membrane enclosing a central cavity filled with an aqueous phase, and therefore, they can encapsulate and deliver both hydrophobic and hydrophilic substances. Niosomal nanocarriers are preferred over other bilayer structures such as liposomes due to their chemical stability, biodegradability, bioco

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Kurakula, Mallesh, Shashank Gorityala, Devang B. Patel, Pratap Basim, Bhaumik Patel, and Saurabh Kumar Jha. "Trends of Chitosan Based Delivery Systems in Neuroregeneration and Functional Recovery in Spinal Cord Injuries." Polysaccharides 2, no. 2 (2021): 519–37. http://dx.doi.org/10.3390/polysaccharides2020031.

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Spinal cord injury (SCI) is one of the most complicated nervous system injuries with challenging treatment and recovery. Regenerative biomaterials such as chitosan are being reported for their wide use in filling the cavities, deliver curative drugs, and also provide adsorption sites for transplanted stem cells. Biomaterial scaffolds utilizing chitosan have shown certain therapeutic effects on spinal cord injury repair with some limitations. Chitosan-based delivery in stem cell transplantation is another strategy that has shown decent success. Stem cells can be directed to differentiate into n

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Lee, Eun-Seong, Ji-Hoon Kim, Jeong-Min Yun, et al. "Functional Polymers for Drug Delivery Systems in Nanomedicines." Journal of Pharmaceutical Investigation 40, spc (2010): 45–61. http://dx.doi.org/10.4333/kps.2010.40.s.045.

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Agrawal, Amit, Dal-Hee Min, Neetu Singh, et al. "Functional Delivery of siRNA in Mice Using Dendriworms." ACS Nano 3, no. 9 (2009): 2495–504. http://dx.doi.org/10.1021/nn900201e.

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Norton, J. E., Y. Gonzalez Espinosa, R. L. Watson, F. Spyropoulos, and I. T. Norton. "Functional food microstructures for macronutrient release and delivery." Food & Function 6, no. 3 (2015): 663–78. http://dx.doi.org/10.1039/c4fo00965g.

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There is a need to understand the role of fat, protein and carbohydrate in human health, and also how foods containing and/or structured using these macronutrients can be designed so that they can have a positive impact on health.

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Mendes, Rafael G., Alicja Bachmatiuk, Bernd Büchner, Gianaurelio Cuniberti, and Mark H. Rümmeli. "Carbon nanostructures as multi-functional drug delivery platforms." J. Mater. Chem. B 1, no. 4 (2013): 401–28. http://dx.doi.org/10.1039/c2tb00085g.

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Lee, M. C., and D. K. Menon. "Sublingual drug delivery during functional magnetic resonance imaging." Anaesthesia 60, no. 8 (2005): 821–22. http://dx.doi.org/10.1111/j.1365-2044.2005.04307.x.

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Hawiger, Jacek. "Noninvasive intracellular delivery of functional peptides and proteins." Current Opinion in Chemical Biology 3, no. 1 (1999): 89–94. http://dx.doi.org/10.1016/s1367-5931(99)80016-7.

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Ding, Jianxun, and Xuesi Chen. "Functional polymer nanocarriers for rational antitumor drug delivery." Nanomedicine: Nanotechnology, Biology and Medicine 14, no. 5 (2018): 1875–76. http://dx.doi.org/10.1016/j.nano.2017.11.359.

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Barclay, Thomas G., Candace Minhthu Day, Nikolai Petrovsky, and Sanjay Garg. "Review of polysaccharide particle-based functional drug delivery." Carbohydrate Polymers 221 (October 2019): 94–112. http://dx.doi.org/10.1016/j.carbpol.2019.05.067.

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Liu, Gang, Magdalena Swierczewska, Seulki Lee, and Xiaoyuan Chen. "Functional nanoparticles for molecular imaging guided gene delivery." Nano Today 5, no. 6 (2010): 524–39. http://dx.doi.org/10.1016/j.nantod.2010.10.005.

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Sun, Wenchao, Mohammed Inayathullah, Martin A. C. Manoukian, et al. "Transdermal Delivery of Functional Collagen Via Polyvinylpyrrolidone Microneedles." Annals of Biomedical Engineering 43, no. 12 (2015): 2978–90. http://dx.doi.org/10.1007/s10439-015-1353-0.

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Tila, Dena, Saeed Ghasemi, Seyedeh Narjes Yazdani-Arazi, and Saeed Ghanbarzadeh. "Functional liposomes in the cancer-targeted drug delivery." Journal of Biomaterials Applications 30, no. 1 (2015): 3–16. http://dx.doi.org/10.1177/0885328215578111.

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Babikova, Dimitrina, Radostina Kalinova, Ivelina Zhelezova, et al. "Functional block copolymer nanocarriers for anticancer drug delivery." RSC Advances 6, no. 88 (2016): 84634–44. http://dx.doi.org/10.1039/c6ra19236j.

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Hasadsri, Linda, Jörg Kreuter, Hiroaki Hattori, Tadao Iwasaki, and Julia M. George. "Functional Protein Delivery into Neurons Using Polymeric Nanoparticles." Journal of Biological Chemistry 284, no. 11 (2009): 6972–81. http://dx.doi.org/10.1074/jbc.m805956200.

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