Littérature scientifique sur le sujet « Gènes de résistances aux antibiotiques »
Créez une référence correcte selon les styles APA, MLA, Chicago, Harvard et plusieurs autres
Consultez les listes thématiques d’articles de revues, de livres, de thèses, de rapports de conférences et d’autres sources académiques sur le sujet « Gènes de résistances aux antibiotiques ».
À côté de chaque source dans la liste de références il y a un bouton « Ajouter à la bibliographie ». Cliquez sur ce bouton, et nous générerons automatiquement la référence bibliographique pour la source choisie selon votre style de citation préféré : APA, MLA, Harvard, Vancouver, Chicago, etc.
Vous pouvez aussi télécharger le texte intégral de la publication scolaire au format pdf et consulter son résumé en ligne lorsque ces informations sont inclues dans les métadonnées.
Articles de revues sur le sujet "Gènes de résistances aux antibiotiques":
SANDERS, P., A. BOUSQUET-MELOU, C. CHAUVIN et P. L. TOUTAIN. « Utilisation des antibiotiques en élevage et enjeux de santé publique ». INRAE Productions Animales 24, no 2 (7 avril 2011) : 199–204. http://dx.doi.org/10.20870/productions-animales.2011.24.2.3254.
Cardinale, Eric, J. D. Perrier, A. Aidara, F. Tall, C. Coudert, I. L. Gueye et M. Konté. « Identification d'une nouvelle salmonelle multirésistante dans une viande de poulet de chair au Sénégal ». Revue d’élevage et de médecine vétérinaire des pays tropicaux 53, no 1 (1 janvier 2000) : 5. http://dx.doi.org/10.19182/remvt.9764.
Bouyahya, A., Y. Bakri, A. Et-Touys, A. Talbaoui, A. Khouchlaa, S. Charfi, J. Abrini et N. Dakka. « Résistance aux antibiotiques et mécanismes d’action des huiles essentielles contre les bactéries ». Phytothérapie 16, S1 (décembre 2018) : S173—S183. http://dx.doi.org/10.3166/phyto-2019-0147.
Mas-Pla, J., M. Boy-Roura, M. Petrovic, M. Villagrasa, I. Lekunberri, CM Borrego, A. Menció, D. Brusi et R. Marcè. « Occurrence et devenir des polluants émergents (antibiotiques) dans un aquifère alluvial et leur influence sur les bactéries multi-résistantes (Bas-Fluvià, Catalogne) ». La Houille Blanche, no 1 (février 2018) : 47–52. http://dx.doi.org/10.1051/lhb/2018007.
Mion, Sonia, Benjamin Rémy, Laure Plener, Éric Chabrière et David Daudé. « Quorum sensing et quorum quenching : Comment bloquer la communication des bactéries pour inhiber leur virulence ? » médecine/sciences 35, no 1 (janvier 2019) : 31–38. http://dx.doi.org/10.1051/medsci/2018310.
Thonda, O. A., A. O. Oluduro, O. O. Adewole et P. O. Obiajunwa. « Phenotypic and genotypic characterization of plasmid-mediated AmpC beta-lactamases in enteric Gram-negative bacteria from patients with lower respiratory tract infections in a tertiary hospital, southwest Nigeria ». African Journal of Clinical and Experimental Microbiology 22, no 4 (27 septembre 2021) : 465–72. http://dx.doi.org/10.4314/ajcem.v22i4.6.
Benbrahim, C., M. S. Barka, L. Benmahdi, A. Zatout et A. Khadir. « Klebsiella pneumoniae producing extended spectrum β-lactamase in Regional Military University Hospital of Oran, Algeria : antibiotic resistance, biofilm formation, and detection of blaCTX-M and blaTEM genes ». African Journal of Clinical and Experimental Microbiology 22, no 1 (26 janvier 2021) : 28–37. http://dx.doi.org/10.4314/ajcem.v22i1.5.
Dumont, Yann, Remy Froissart, Anne-Laure Bañuls, Lucas Bonzon, Hélène Jean-Pierre et Sylvain Godreuil. « Bactéries anaérobies et résistances aux antibiotiques ». Revue Francophone des Laboratoires 2018, no 505 (septembre 2018) : 57–62. http://dx.doi.org/10.1016/s1773-035x(18)30256-9.
Vu-Thien, H. « Pleuro-pneumopathies : épidémiologie bactérienne et résistances aux antibiotiques ». Archives de Pédiatrie 15 (octobre 2008) : S81—S83. http://dx.doi.org/10.1016/s0929-693x(08)74221-0.
BOICHARD, D., Aurélien CAPITAN, Coralie DANCHIN-BURGE et Cécile GROHS. « Avant-propos : Anomalies génétiques ». INRA Productions Animales 29, no 5 (9 janvier 2020) : 293–96. http://dx.doi.org/10.20870/productions-animales.2016.29.5.2995.
Thèses sur le sujet "Gènes de résistances aux antibiotiques":
Tremblay, Simon. « Étude moléculaire du recrutement des gènes de résistance aux antibiotiques ». Thesis, Université Laval, 2007. http://www.theses.ulaval.ca/2007/24374/24374.pdf.
Papadopoulou, Barbara. « Dissémination des gènes de résistance aux antibiotiques chez les entérobactéries et Campylobacter ». Paris 11, 1988. http://www.theses.fr/1988PA114815.
Ayoub-Moubareck, Carole. « Le transfert horizontal des gènes de résistance aux antibiotiques au sein de l'écosystème intestinal ». Paris 5, 2005. http://www.theses.fr/2005PA05P609.
The intestinal ecosystem corresponds to a potential reservoir of antibiotic resistant bacteria capable of acquiring or transmitting their resistance genes to bacteria belonging to different genera. By using the model of glycopeptide resistance in Enterococci, we demonstrated that the intra- and inter-species transfer of resistance genes was possible from animal to human bacteria in vitro and in vivo and occurred at a high frequency, compatible with the proportion the Enterococci present in food. A phenomenon of co-transfer allowing the acquisition of resistance to various antibiotic classes was noted. The presence of sub-inhibiting concentrations of macrolides in the conjugation medium increased significantly the frequency of transfer of the vanA gene in vivo. We highlighted the role of barrier of the flora and its capacity to inhibit the growth of exogenic bacteria (donor and recipient) and to limit gene transfer in the digestive tract. We evaluated the impact of certain strains of Bifidobacterium (bacteria with probiotic potential) on gene transfer and noted an antagonistic effect on the transfer of bla genes between Enterobacteriaceae. The Lebanese epidemiologic studies showed the absence of digestive colonization by glycopeptide resistant Enterococci but pinpointed the dissemination of CTX-M-15 producing Escherichia coli in the hospitals and the community
Trudel, Mélanie V. « Étude et détection des gènes de résistance aux antibiotiques chez Aeromonas salmonicida sous-espèce salmonicida ». Master's thesis, Université Laval, 2015. http://hdl.handle.net/20.500.11794/25937.
Aeromonas salmonicida subspecies salmonicida, a pathogenic bacterium that infects fish, causes a disease named furunculosis, which is treated with antibiotics. The latters are not as effective because of antibiotic resistances. As the susceptibility tests require seven days, a multiplex PCR targeting the genes coding resistances against homologated antibiotics (sulfonamides and trimethoprim, tetracyclines, chloramphenicols) would detect resistance rapidly. Following the characterization of genomic sequences and optimization of multiplex PCR, several strains of A. salmonicida subspecies salmonicida were tested and the results were compared with those obtained by the susceptibility tests. It shows that the kit is highly efficient even more rapidly than the susceptibility tests to detect resistance to sulfonamides, tetracyclines and chloramphenicols while being faster. A deeper knowledge about sulfonamides and trimethoprim resistance and the improvement of the diagnostic kit should be considered.
Negro, Veronica. « Caractérisation de la protéine RadD et identification des gènes essentiels en présence de faibles doses de tobramycine ». Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS052.
Sub-inhibitory concentrations (sub-MIC) of antibiotics play an important role in selection and development of resistances. Unlike Escherichia coli, Vibrio cholerae induces its SOS response in presence of sub-MIC aminoglycosides. SOS is also involved in genome plasticity and in the acquisition of resistance to antibiotics. In order to select for V. cholerae mutants that do not induce low aminoglycoside-mediated SOS induction, we developed a genetic screen for the isolation of mutants in which induction of the SOS response by sub-MICs of aminoglycosides is lost. One of these mutants is inactivated for the radD gene, which encodes a putative DNA/RNA helicase. RadD is involved in the resolution of double strand DNA breaks caused by treatment with sub-MIC of tobramycine. We demonstrate that R-loops are at the origin of DSBs formed in the absence of radD in tobramycine.We propose that DNA lesions formed upon aminoglycoside treatment are repaired through the formation of ssDNA intermediates, inducing SOS. RNAP could stalls on these lesions and forms R-loops, that, if not repaired, can lead to the formation of DSB and genome instability. RadD could play a role in the resolution of R-loops. These results highlighted the fact that sub-MIC of tobramycine leads to DNA double strand breaks, at least partly through R-loop formation. Tobramycin is an aminoglycoside that targets the ribosome. The formation of DSBs by such an antibiotic can be surprising as DNA damage formation by an antibiotic that targets translation is not expected. In order to understand the pathways involved in the response to low doses of tobramycin we adopted a high throughput Tn-seq approach to determine which genes are important in maintaining the integrity of the cell in the presence of antibiotics at low doses
Derongs, Lorine. « Impact de la méthanisation agricole mésophile voie liquide sur le devenir de Clostridia pathogènes et de gènes de résistance aux antibiotiques ». Thesis, Rennes, Agrocampus Ouest, 2021. http://www.theses.fr/2021NSARB348.
It is important to guarantee the safe use of digestate for land application. The first objective of this work was to estimate, at field scale, the impact of three mesophilic digesters on the virulence and on the antibiotic resistance of C. perfringens, a pathogenic, strictly anaerobic bacterium which may grow in digesters. Anaerobic digestion did not change the distribution of the toxinotypes, mostly represented by type A (78.3% of the isolates), nor the antimicrobial resistance profiles of the isolates. Some isolates were highly resistant to antibiotics used in human medicine, especially vancomycin and imipenem. The second objective was to evaluate on semi-continuous mesophilic pilots, the effect of hydraulic retention time (HRT), organic loading rate and pretreatment of manure (70 °C, 1 h), on (i) four bacteria (E. coli, enterococci, C. perfringens and C. difficile), (ii) microbial communities and (iii) 14 antibiotic resistance genes (ARG) and the gene intl1The thermal pre-treatment had the greatest effect on the four bacteria: E. coli was not detected in digestates and the level of C. perfringens was reduced by a factor of 10. However it led to a slight increase in the level of C. difficile in the manure. Although no enterococci were detected in the heated manure, they were still present in the digestates, suggesting their ability to grow in the pilots inoculated with a digestate at the beginning of each experiment. Mesophilic anaerobic digestion changed the composition of bacterial communities by increasing the relative abundance of Bacteroidetes and decreasing the abundance of Firmicutes. The process reduced the concentration of the ARG (the Log reduction ranged from 0.1 to 2). The increasing of the HRT and the application of the thermal pretreatment led to a reduction in the number of OTU but did not significantly impact the Log reduction of the ARG and of the gene intl1
Avrain, Laëtitia. « Biorésistance des Campylobacter des filières avicole et porcine : analyse des transferts de gènes de résistance aux antibiotiques ». Lyon 1, 2003. http://www.theses.fr/2003LYO10127.
Laflamme, Christian. « Agents du bioterrorisme : détection in situ de gènes de résistance aux antibiotiques chez les spores de Bacillus sp ». Thesis, Université Laval, 2008. http://www.theses.ulaval.ca/2008/25821/25821.pdf.
Brochu, Eliel. « Métagénomique, culturomique et sélectomique recombinante pour la caractérisation de gènes de résistance aux antibiotiques dans le microbiote intestinal humain ». Master's thesis, Université Laval, 2018. http://hdl.handle.net/20.500.11794/38129.
The human intestinal microbiota is an important and poorly known antibiotic resistance genes reservoir. In this study, we explored resistance genes from the microbiota of healthy volunteers before and after exposure to the β-lactam cefprozil antibiotic. Three approaches were used to characterise resistance genes in the human microbiota and examine alteration by antimicrobials: metagenomics, culturomics and recombinant selectomics. Metagenomic and culturomic sequencing of intestinal microbiota enabled identification of several genes for resistance to β-lactams and other antibiotics. However, culturomics allowed identification of these genes in more participants than metagenomics. Culturomics highlighted the presence of the clinically important vancomycin resistance vanD-like genes in the microbiota of about 46% of participants compared to 8% with metagenomics. Culturomics also showed that in vitro and in vivo β-lactams exposition stimulates the emergence of vanD genes. Recombinant selectomics, which is based on the construction of expression libraries made with bacterial DNA, was also used to functionally characterise β-lactam resistance genes from the cultivable intestinal bacteria. It allowed identification and characterisation of five different β-lactamases including two with an extended-spectrum activity. The majority of β-lactamases genes was associated with other resistance genes and/or mobile elements. This study demonstrated that culture favors the identification of genes undetected by direct metagenomic sequencing and selectomics was a powerful tool to characterise gene functions. It also demonstrated that intake of a commonly used antibiotic of the β-lactam family can influence the abundance of bacteria containing resistance genes to an antibiotic from another class, such as vancomycin, which is a last resort antibiotic.
Coyne, Sébastien. « Génétique de la multi-résistance aux antibiotiques chez Acinetobacter baumannii et Pseudomonas aeruginosa ». Paris 7, 2010. http://www.theses.fr/2010PA077025.
Acinetobacter baumannii and Pseudomonas aeruginosa are two major nosocomial pathogens with a high propensity to develop resistance to antibiotics. We have designed a microarray that allows to both quantify the expression of efflux Systems and detect acquired résistance genes in A. Baumannii. Study of spontaneous mutants showed (i) overexpression of the AdeABC efflux System in one mutant, likely due to a new mutation in AdeS, the sensor of a two-component regulatory System ; (ii) overexpression of AdelJK in several mutants suggesting that this pump can contribute to acquired résistance ; (iii) overexpression of a new RND pump, AdeFGH, in two mutants, conferring multidrug résistance and likely due to due to mutations in adeL encoding a LysR-type transcriptional regulator. Study of the genetic environment of the ant(4')-IIb gene in P. Aeruginosa clinical isolates led to the characterization of Tn6061, a 26. 5-kb element conferring résistance to six unrelated drug classes. Ant(4')-Hb was present and flanked by directly repeated copies of ISCR6 in ail but one of the strains studied, consistent with ISCR6-mediated gene acquisition. Tn6061 was chromosomally located in six strains and plasmid-borne in the remaining isolate, suggesting horizontal acquisition. Furthermore, an IS6100 element, that ended Tn6061, was found to be responsible for large chromosomal inversions by duplication-insertion. This work indicates that multidrug resistance in A. Baumannii and P. Aeruginosa can result from one-step genetic events, either mutations leading to overexpression of an efflux System or acquisition of foreign elements carrying resistance determinants
Livres sur le sujet "Gènes de résistances aux antibiotiques":
Clavilier, L., O. Letodé et F. Hervieu. Gènes de résistance aux antibiotiques et plantes transgéniques. INRA, 2001.