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Bibliographies thématiques / Glycoderivatives

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Littérature scientifique sur le sujet « Glycoderivatives »

Auteur : Grafiati

Publié le 9 mars 2023

Mis à jour le 31 juillet 2025

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Articles de revues sur le sujet "Glycoderivatives"

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Pascariu, Mihai-Cosmin, Lucian Mircea Rusnac, and Ana-Maria Macsim. "Tethered Glycoderivatives with Unsaturated Spacer: Synthesis and Characterization." Synthetic Communications 42, no. 17 (2012): 2503–11. http://dx.doi.org/10.1080/00397911.2011.561943.

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Ramos-Soriano, Javier, Beatriz M. Illescas, Alfonso Pérez-Sánchez, et al. "Topological and Multivalent Effects in Glycofullerene Oligomers as EBOLA Virus Inhibitors." International Journal of Molecular Sciences 23, no. 9 (2022): 5083. http://dx.doi.org/10.3390/ijms23095083.

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The synthesis of new biocompatible antiviral materials to fight against the development of multidrug resistance is being widely explored. Due to their unique globular structure and excellent properties, [60]fullerene-based antivirals are very promising bioconjugates. In this work, fullerene derivatives with different topologies and number of glycofullerene units were synthesized by using a SPAAC copper free strategy. This procedure allowed the synthesis of compounds 1-3, containing from 20 to 40 mannose units, in a very efficient manner and in short reaction times under MW irradiation. The gly

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Andreu, Alicia, Marija Ćorović, Carla Garcia-Sanz, et al. "Enzymatic Glycosylation Strategies in the Production of Bioactive Compounds." Catalysts 13, no. 10 (2023): 1359. http://dx.doi.org/10.3390/catal13101359.

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Enzymatic glycosylation is a versatile and sustainable biotechnological approach that plays a pivotal role in the production of bioactive compounds. This process involves the enzymatic transfer of sugar moieties onto various acceptor molecules, such as small molecules, peptides, or proteins, resulting in the synthesis of glycosides. These glycosides often exhibit enhanced bioactivity, improved solubility, and enhanced stability, making them valuable in pharmaceuticals, nutraceuticals, and the food industry. This review explores the diverse enzymatic glycosylation strategies employed in the syn

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D’Orazio, Giuseppe, and Barbara La Ferla. "Synthesis of a Small Library of Glycoderivative Putative Ligands of SGLT1 and Preliminary Biological Evaluation." Molecules 29, no. 21 (2024): 5067. http://dx.doi.org/10.3390/molecules29215067.

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Sodium–glucose co-transporter 1 (SGLT1) is primarily expressed on the membrane of enterocytes, a type of epithelial cell found in the intestines, where it mediates the unidirectional absorption of glucose and galactose. Beyond its well-established role in nutrient absorption, SGLT1 also plays a protective role in maintaining the integrity of the intestinal barrier. Specifically, the natural ligand of SGLT1 (d-glucose) and a synthetic C-glucoside developed by our group can induce a protective anti-inflammatory effect on the intestinal epithelium. In this paper, we report the creation of a small

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Pascariu, Mihai-Cosmin, and Lucian Mircea Rusnac. "Selective deprotection of tethered glycoderivatives with unsaturated spacer." Heterocyclic Communications 17, no. 3-4 (2011). http://dx.doi.org/10.1515/hc.2011.022.

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Chai, Luxiao, Yiping Chen, Xibo Yan, et al. "Poly(vinyl alcohol)s and Their Glycoderivatives as Efficient Shell-Builders of Nanocapsules by Nanoprecipitation." Biomacromolecules, May 16, 2024. http://dx.doi.org/10.1021/acs.biomac.4c00213.

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Thèses sur le sujet "Glycoderivatives"

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D'ORAZIO, GIUSEPPE. "Glycoderivatives: drug candidates and molecular tools." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2013. http://hdl.handle.net/10281/41154.

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The research project is focused on the development and the synthesis of glycoderivatives as potential drug candidates, for therapeutic use, and as molecular tools, for the study of biological processes. The project includes the study of SGLT1 (Sodium-Glucose co-transporter 1), its role in inflammatory processes and the development of potential carbohydrate-based anti-inflammatory agents. Furthermore, new glycoderivatives and glycoconjugates will be synthetized for other potential pharmacological applications such as the targeting of cytotoxic drugs, as novel potential anticancer agents, and f

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PAIOTTA, ALICE. "Synthesis of Glycoderivatives as Molecular Tools in Medicinal Chemistry and Nano-Medicinal Chemistry." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2018. http://hdl.handle.net/10281/199137.

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Durante il terzo anno di dottorato mi sono occupata della sintesi finale dei glicomimetici del substrato naturale dell’enzima AGM1 GlcNAc-6P o del prodotto GlcNAc-1P. Le sintesi messe a punto sono necessarie per ottenere prodotti finali utilizzabili come strumenti molecolari chimici per studiare il ruolo dell’HBP nella regolazione della proliferazione e la sopravvivenza delle cellule tumorali. I prodotti presentati (caratterizzati mediante NMR (1H. COSY, HSQC e 13C) e Massa) sono stati preparati protetti (acetilati sugli ossidrili) per i test cellulari per favorire la loro diffusione attr

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