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Littérature scientifique sur le sujet « Hepatoprotective properties »

Auteur : Grafiati

Publié le 2 juin 2025

Mis à jour le 31 juillet 2025

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Articles de revues sur le sujet "Hepatoprotective properties"

Heidari, Reza, Mohammad Reza Arabnezhad, Mohammad Mehdi Ommati, Negar Azarpira, Elham Ghodsimanesh, and Hossein Niknahad. "Boldine Supplementation Regulates Mitochondrial Function and Oxidative Stress in a Rat Model of Hepatotoxicity." Pharmaceutical Sciences 25, no. 1 (2019): 1–10. http://dx.doi.org/10.15171/ps.2019.1.

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Background: The xenobiotics-induced liver injury is a clinical complication. Hence, finding new hepatoprotective strategies has clinical value. Oxidative stress and its subsequent complications are major mechanisms involved in xenobiotics-induced hepatotoxicity. Boldine is one of the most potent antioxidant molecules widely investigated for its protective properties in different experimental models. In the current study, the hepatoprotective properties of boldine and its potential mechanisms of hepatoprotection have been investigated. Methods: Rats received thioacetamide (TAA; 200 mg/kg, i.p)

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Okovity, S. V., K. L. Raikhelson, A. V. Volnukhin, and D. A. Kudlai. "Hepatoprotective properties of glycyrrhizic acid." Experimental and Clinical Gastroenterology, no. 12 (December 23, 2020): 96–108. http://dx.doi.org/10.31146/1682-8658-ecg-184-12-96-108.

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The review is devoted to the problem of treatment of non-alcoholic fatty liver disease, which is the most common pathology of the hepato-biliary system worldwide and is characterized by an increasing frequency, including of more severe forms. A wide range of pathogenetic relationships of non-alcoholic fatty liver disease with diseases of other organ systems, primarily with diseases of the cardiovascular system, type 2 diabetes mellitus, chronic kidney disease and diseases of the biliary tract, is presented. The main mechanisms of comorbidity are insulin resistance, oxidative stress, inflammati

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Heuman, Douglas M. "Hepatoprotective properties of ursodeoxycholic acid." Gastroenterology 104, no. 6 (1993): 1865–69. http://dx.doi.org/10.1016/0016-5085(93)90672-y.

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Delgado-Montemayor, Cecilia, Paula Cordero-Pérez, Liliana Torres-González, et al. "Development of a Hepatoprotective Herbal Drug from Turnera diffusa." Evidence-Based Complementary and Alternative Medicine 2022 (January 10, 2022): 1–10. http://dx.doi.org/10.1155/2022/5114948.

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The incidence of liver diseases, such as nonalcoholic fatty liver disease and drug-induced liver injury, continues to rise and is one of the leading causes of acute hepatitis. Current trends suggest that these types of conditions will increase in the coming years. There are few drugs available for the prevention or treatment of hepatic diseases, and there is a growing need for the development of safe hepatoprotective agents. The medicinal plant, Turnera diffusa, has many ethnopharmacological uses, one of which is the production of a flavonoid named hepatodamianol, which is the principal compon

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Damle, Mrinalini C., Sachin V. Tembhurne, and Swapnil R. Todkar. "Evaluation of Hepatoprotective Activity of Hydroalcoholic Extract of Onion Peels Containing Protocatechuic Acid." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 82–88. http://dx.doi.org/10.22270/jddt.v9i4.2982.

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India is the second largest country for cultivation of onion. 19.90% of onion is cultivated in India. Onion that is Allium cepa family Amaryllidaceae used in daily diet for taste. Onions also have number of medicinal properties, such as hepatoprotection, anticancer, antifungal, antioxidant, antiulcer, anti-agging, anti-inflammatory, anticancer etc.[1-2] The dried scales or peels of onion also have the same medicinal constituents with same activity as raw onions. The onion peels contains flavonoids, such as anthocyanins, flavones (qurcertin and its derivatives), ferulic, Gallic, protocatechuic

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Lee, Ji-Eun, Da-Eun Jo, An-Jung Lee, et al. "Hepatoprotective and antineoplastic properties ofProtaetia brevitarsislarvae." Entomological Research 44, no. 6 (2014): 244–53. http://dx.doi.org/10.1111/1748-5967.12075.

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Al-Tameemi, Zahraa Salam, Hany A. Al-Hussaniy, Ali Mahmoud Al-Samydai, Meena Akeel Naji, Fuaad I. Iraqi, and Fatima A. Naji. "A detailed analysis of Spirulina's therapeutic properties in liver protection, oxidative stress reduction, and cancer management." Current Issues in Pharmacy and Medical Sciences 38, no. 1 (2025): 27–30. https://doi.org/10.12923/cipms-2025-0004.

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Spirulina, a cyanobacterium recognized for its nutritional benefits, has recently garnered attention for its potential therapeutic properties. This review aims to comprehensively consolidate current knowledge on the pharmacological attributes of Spirulina species, focusing on their hepatoprotective, antioxidant and anticancer effects. An exhaustive literature search was conducted, collating data from empirical studies, clinical trials and reviews pertaining to the pharmacological effects of Spirulina. Spirulina exhibits significant hepatoprotective activities, evidenced by its ability to mitig

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Tan, Shancai, Qiuxia Lu, Yueyue Shu, Yiran Sun, Fang Chen, and Lin Tang. "Iridoid Glycosides Fraction Isolated fromVeronica ciliataFisch. Protects against Acetaminophen-Induced Liver Injury in Mice." Evidence-Based Complementary and Alternative Medicine 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/6106572.

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Veronica ciliataFisch. has traditionally been used in Tibetan medicine for the treatment of hepatitis, cholecystitis, rheumatism, and urticaria. We analyzed the chemical composition of the iridoid glycosides fraction (IGF) isolated fromV. ciliataand evaluated the antioxidant and hepatoprotective properties. The IGF was separated by high-speed countercurrent chromatography (HSCCC) and the main compounds were identified by ultra-performance liquid chromatography coupled to a photodiode array. We determined the in vitro antioxidant ability of the IGF through radical scavenging assays and assessed

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Suponko, J. V., та N. I. Shtemenko. "Вплив нанопрепаратів кластерних сполук ренію на активність ферментів печінки в моделі пухлинного росту". Visnyk of Dnipropetrovsk University. Biology, medicine 1, № 2 (2010): 76–80. http://dx.doi.org/10.15421/021030.

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Enzymes’ level in rat’s hepatocytes under Guerin's carcinoma T8 development as well as after injection of rhenium compounds and cis-platin has been studied. It has been determined that the decrease of enzymatic activity to the level of the animals of control group was observed at the simultaneous injection of cis-platin and cluster rhenium compounds in nanoliposomal and water-soluble forms. That confirms possible hepatoprotective properties of the rhenium compounds. It has been shown that hepatoprotective properties of rhenium cluster compounds mostly don’t depend on the form of their injectio

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Akhilesh, Singhai* Rajesh Gour** &. Sagar Singh Jough***. "HEPATOPROTECTIVE PROPERTIES OF HERBAL PLANTS: A REVIEW." International Journal of Scientific Research and Modern Education (IJSRME) 8, no. 1 (2023): 82–86. https://doi.org/10.5281/zenodo.8077164.

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The body's many physiological functions depend on the liver, which is the most significant organ in this regard. The presence of inflammatory cells in the liver's tissue distinguishes hepatitis, an inflammation of the organ. kinds A, B, C, D, and E relate to the five basic kinds of viruses. The weight of disease and mortality is particularly concerning for these five categories. A serious health issue that affects the pharmaceutical business, drug regulatory organisations, and health care providers is liver damage or malfunction. For a very long time, liver illness has been treated usi

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Thèses sur le sujet "Hepatoprotective properties"

Boateng, Anthony Osei. "Hepatoprotective properties of Gentiana spp. against non-alcoholic fatty liver disease (NAFLD)." Thesis, University of Westminster, 2018. https://westminsterresearch.westminster.ac.uk/item/q4yzy/hepatoprotective-properties-of-gentiana-spp-against-non-alcoholic-fatty-liver-disease-nafld.

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Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease characterised by the accumulation of fat in the liver. It is estimated that 33 % of the UK population have NAFLD with 2-5 % progressing to non-alcoholic steatohepatitis (NASH). Due to a lack of an outright therapy for NAFLD, treatment has been mainly focussed on managing the conditions associated with the disease such as obesity, diabetes mellitus and hyperlipidaemia. This study aimed to investigate the means by which hepatocyte protection is conferred by Gentiana plants (Gentiana lutea, Gentiana macrophylla, Gentiana scabra and

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Salvador, Cátia Sofia Clemente. "Caracterização de cogumelos silvestres da espécie Amanita ponderosa: produção de metabolitos com atividade biológica." Doctoral thesis, Universidade de Évora, 2014. http://hdl.handle.net/10174/13391.

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Amanita ponderosa é uma espécie de cogumelos silvestres, comestível, característica de alguns microclimas mediterrânicos, existente na Península Ibérica. Neste estudo, avaliaram-se as propriedades biológicas e toxicológicas destes cogumelos e culturas, com vista a valorizar o seu potencial biotecnológico. Desenvolveu-se também uma metodologia de monitorização, utilizando técnicas de microanálise e imunológicas para screening e análise da especificidade de produção dos compostos bioativos. Os corpos de frutificação apresentaram um relevante conteúdo mineral e um perfil molecular correlacionável

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Yu, Wan-Jhen, and 余宛蓁. "Functional properties and evaluation hepatoprotective of Chinese multiherbal formula beverage." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/15926739250876094611.

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碩士<br>國立嘉義大學<br>食品科學系研究所<br>96<br>The people use the Chinese herb medicine to prevent or cure disease for a long time, but former research often was primarily discusses by the simplex Chinese herb medicine that provides the effect.This research objective was development Chinese multiherb beverage for hepatoprotective. First develops the best preference Chinese multiherb beverage in this research, analyzes proximate compositions and the element, and sensory evaluation of Chinese multiherbal formula beverage, then discusses analysis the Chinese multiherbal formula beverage function characteristi

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Chapitres de livres sur le sujet "Hepatoprotective properties"

Olcay, Bulent. "The Genus Mentha L." In Medicinal Spices. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359340.8.

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Mentha, a genus of plants known throughout history for its use as a spice by humans, has been documented since ancient times. This famous plant has been used both as a spice and for its medicinal properties in the treatment of many ailments. Mentha spp have anti-inflammatory, antioxidant, antinociceptive, hepatoprotective, antibacterial and antifungal activities. Pharmacological evidence supports the biological activities of these species, which are widely used in traditional medicine.

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Carini, R., A. Comoglio, H. Basaga, E. Albano, and G. Poli. "Antioxidant and Hepatoprotective Properties of IdB 1016, A New Flavanolignan Complex." In Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-3520-1_25.

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Leonov, Victor, Olga Pavlova, Olga Gulenko, Nikolai Zhelonkin, and Lyudmila Varfolomeyeva. "Study of Hepatoprotective and Detoxifying Properties of Plant Antioxidants in Tetrachloromethane-Induced Oxidative Stress." In Fundamental and Applied Scientific Research in the Development of Agriculture in the Far East (AFE-2022). Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-37978-9_101.

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Savinkov, Alexey, Sergey Borisov, Marina Semenenko, Ksenia Semenenko, and Elena Kuzminova. "Study of Hepatoprotective Properties of the Complex of Biologically Active Substances in Hepatopathies of Young Pigs." In Fundamental and Applied Scientific Research in the Development of Agriculture in the Far East (AFE-2021). Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-91405-9_6.

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Selvakesavan, Rajendran K., Dariusz Kruszka, Preeti Shakya, Dibyendu Mondal, and Gregory Franklin. "Impact of Nanomaterials on Plant Secondary Metabolism." In Nanomaterial Interactions with Plant Cellular Mechanisms and Macromolecules and Agricultural Implications. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-20878-2_6.

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AbstractPlants encounter various nanomaterials (NMs) as pesticides and fertilizers. It is also possible that nanomaterials reach plants as waste from consumer products and industry. The effects of such NMs on plants have been widely studied, and both positive and negative effects of NMs on plant growth and development have been reported. Recent metabolomics studies suggest that nanoparticles affect the concentration of secondary metabolites in plants by modulating reactive nitrogen/oxygen species, gene expression, and signaling pathways. Secondary metabolites are plant compounds that accumulat

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Reyes-Gordillo, K., R. Shah, M. R. Lakshman, R. E. Flores-Beltrán, and P. Muriel. "Hepatoprotective Properties of Curcumin." In Liver Pathophysiology. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-804274-8.00049-7.

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Ray, Sonali. "Hepatoprotective Effects of Curcumin from Curcuma Longa L.: A Comprehensive Account." In Trends in Chemical and Biological Research. Lincoln University College, Malaysia, 2023. http://dx.doi.org/10.31674/book.2023tcbr009.

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Since time immemorial, man has benefited from the active phytochemicals derived from plants. One such novel medicinal plant is Curcuma longa, or turmeric, which has a diverse usage from being a household spice to being a therapeutic gem. The medicinal value of the plant is due to curcumin, a polyphenol. It has remarkable pharmacological properties like antimicrobial, anti-inflammatory, antidiabetic, antimutagenic and hepatoprotective, among many others. In the present account, the hepatoprotective potential of the novel plant has been focused upon due to the increasing cases of various liver d

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Gerapati, Kiran. "Innovative Drug Delivery Systems For Herbal Hepatoprotective Agents: Advances And Future Directions." In Advancements in Hepatoprotective Herbal Medicines Current Trends, Significance and Future Perspectives. Genome Publications, 2025. https://doi.org/10.61096/978-81-981372-8-9_16.

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The growing prevalence of liver diseases has intensified the search for more effective hepatoprotective therapies. While herbal medicines have demonstrated hepatoprotective properties, their therapeutic potential is often limited by poor bioavailability, rapid metabolism, and low aqueous solubility. Recent advancements in innovative drug delivery systems offer promising solutions to enhance the efficacy of herbal hepatoprotective agents. This chapter explores cutting-edge approaches, including liposomes, phytosomes, polymeric nanoparticles, nanoemulsions, solid lipid nanoparticles, and hydroge

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Pandi, Vignesh, and Sam Johnson Udhayachandar. "Hepatoprotective Activity of Proline Derivatives." In Understanding Hepatotoxicity - Causes, Symptoms and Prevention [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1010711.

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The liver plays a dynamic role in detoxification, metabolic regulation, and maintaining physiological balance, yet it is highly prone to damage from drugs and toxic substances. Paracetamol overdose is a well-known cause of drug-induced liver injury (DILI), emphasizing the importance of finding effective protective compounds. Proline has shown promise in protecting the liver due to its antioxidant properties and ability to preserve mitochondrial function. This study inspects the liver-protective potential of a synthetic proline-based compound, 1-[(2-hydroxyanilino) acetyl] pyrrolidine-2-carboxy

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"Peptides of a Plant Origin Exerting Hepatoprotective Properties." In Chemical and Biochemical Physics. Apple Academic Press, 2016. http://dx.doi.org/10.1201/b19939-25.

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Actes de conférences sur le sujet "Hepatoprotective properties"

Ponamarev, V. S. "The influence of the experimental composition on some hematological parameters in zebrafish." In SPbVetScience. FSBEI HE St. Petersburg SUVM, 2023. http://dx.doi.org/10.52419/3006-2023-11-41-44.

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At the moment, aqua and mariculture is experiencing a tremendous need for modern drugs for the pharmacocorrection of pathologies of non-infectious etiology, which are complex and have a universal integral pharmacological response. Determination of hepatoprotective properties was carried out according to the method described in step 4, however, the parity experimental group received the studied composition (combination of ursodeoxycholic and chenodeoxycholic acids in encapsulated form) at a dosage of 20 mg/kg (by the amount of bile acids). As a result of the study, no negative changes were note

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O.I., Vasiliadi, Kuzminova E.V., and Dolgov E.P. "STUDYING THE PHARMACOLOGICAL PROPERTIES OF A HEPATOPROTECTIVE DRUG DURING EXPERIMENTAL AMMONIA INTOXICATION OF BROILER CHICKENS." In OF THE ANNIVERSARY Х INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE «INNOVATIVE TECHNOLOGIES IN SCIENCE AND EDUCATION» («ITSE 2022» CONFERENCE). DSTU-Print, 2022. http://dx.doi.org/10.23947/itse.2022.33-36.

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The article presents the results of the study of the pharmacological efficiency of the hepatoprotective drug phytosomin in experimental ammonia intoxication of broiler chickens. The conducted studies have determined that phytosomin contributes to an increase in body weight gain in poultry, and its preventive use allows to increase the period of manifestation of clinical signs of ammonia intoxication and their severity, to reduce pathological changes in the organs of the respiratory and circulatory systems.

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Tarasova, E., and Liliya Matrosova. "EFFECTIVENESS OF GALLUASORB IN THE CORRECTION OF LIPID PEROXIDATION PROCESSES IN MIXED MYCOTOXICOSIS." In XIV All-Russian Scientific and Practical Conference of Young Scientists “Achievements and Prospects of Development of the Agroindustrial Complex of Russia” with international participation, dedicated to the 300th anniversary of the Russian Academy of Sciences. TRIA FRC Kazan Scientific Center of RAS, 2024. https://doi.org/10.37071/conferencearticle_67337e414af305.01587753.

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The effectiveness of the multicomponent feed additive “Galluasorb”, developed at the the Federal Center for Toxicological, Radiation and Biological Safety» (FSBSI «FCTRBS-ARRVI»), which has sorption, antioxidant, immunostimulating, and hepatoprotective properties, in correcting the processes of lipid peroxidation in mixed mycotoxicosis, expressed in reducing the amount of malondialdehyde in the blood of experimental animals, has been shown

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Lyamtseva, A. K., and T. R. Romanovskaya. "INFLUENCE OF THE GANODERMA LUCIDUM FRUIT BODIES EXTRACT ON INNATE IMMUNITY INDICATORS IN THE MODEL OF AN IMMUNE RESPONSE IN BALB/C MICE." In SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2021. http://dx.doi.org/10.46646/sakh-2021-2-62-65.

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Modern laboratory and clinical studies have revealed antitumor, immunomodulatory, hepatoprotective, antioxidant, and other properties of Ganoderma lucidum due to the presence in its composition of individual components with pharmacological activity. Its effects on the immune system are varied. The main immunotropic effect of the Ganoderma lucidum fruit bodies extract is aimed at increasing the indicators of the phagocytic activity of peritoneal macrophages and increasing the activity of the classical pathway of activation of the complement system.

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E.P., Dolgov, Kuzminova E.V., Semenenko M.P., and Vasiliadi O.I. "STUDY OF THE OPTIMUM RATIO OF COMPONENTS AND THE SPECIFIC ACTIVITY OF THE FEED ADDITIVE ON SINGLE-CELLULAR CULTURES PARAMECIUM CAUDATUM." In OF THE ANNIVERSARY Х INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE «INNOVATIVE TECHNOLOGIES IN SCIENCE AND EDUCATION» («ITSE 2022» CONFERENCE). DSTU-Print, 2022. http://dx.doi.org/10.23947/itse.2022.57-59.

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The article presents data on the effect of feed additives on the membrane-stabilizing effect in ciliates. Various combinations of feed additive components and the most optimal ratio of components providing a pronounced stabilizing effect are presented, the biological properties of plant fibers enhanced with hepatoprotective and desensitizing substances are described. The biological activity of the feed additive was established, which was confirmed by the length of the stopping dose and the integrity of the cell membrane.

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