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1

Ernest van Heurn, L. W., and Peter R. G. Brink. "The history of percutaneous tracheotomy." Journal of Laryngology & Otology 110, no. 8 (1996): 723–26. http://dx.doi.org/10.1017/s0022215100134802.

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AbstractPercutaneous tracheotomy is a surgical procedure for inserting a tracheal cannula into the tracheal lumen without a large incision, without extensive dissection of pretracheal tissue and without exposure of the trachea. Ciaglia's report on the procedure a decade ago led to this technique gaining popularity, although its origin is much older.
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Takaishi, Kazumi, Shinji Kawahito, and Hiroshi Kitahata. "Management of a Patient With Tracheal Stenosis After Previous Tracheotomy." Anesthesia Progress 68, no. 4 (2021): 224–29. http://dx.doi.org/10.2344/anpr-68-03-08.

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Tracheal stenosis after tracheotomy can cause difficult airway management and respiratory complications. It is difficult to predict tracheal stenosis after tracheotomy based on a patient's symptoms as the symptoms of tracheal stenosis appear only after they become severe. In patients with a history of previous tracheotomy, it is important to consider the risk factors for tracheal stenosis. Detailed preoperative evaluation of patients with a history of previous tracheotomy is essential and should include 3-dimensional assessment of the airway. We report the preoperative assessment and periopera
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Babić, I., Z. Tolić, J. Jakobović, and S. Kušt. "Tracheotomy in pediatric patients." Paediatria Croatica 53, no. 2 (2009): 83–91. http://dx.doi.org/10.13112/pc.896.

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Pediatric tracheotomy differs from tracheotomy in adults, not only in indications but also in operative techniques, postoperative complications and postoperative care. Indications for tracheotomy have changed during history. Whereas upper airway infections such as diphtheria and croup were the main reasons for tracheotomy in the past, the indications have been modified upon the discovery of antibiotics. Currently, tracheotomy is mostly used for upper airway obstruction due to congenital malformations, or to facilitate assisted ventilation and lower airway toilet. Pediatric tracheotomy is more
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4

Volpi, David, Daniel B. Kuriloff, Pi-Tang Lin, and Charles P. Kimmelman. "Risk Factors for Intubation Injury of the Larynx." Annals of Otology, Rhinology & Laryngology 96, no. 6 (1987): 684–86. http://dx.doi.org/10.1177/000348948709600614.

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The endolaryngeal structures are subjected to insult from prolonged endotracheal intubation. Factors that may exacerbate this injury include intubation technique, duration of intubation, tube geometry and constitution, frequency of reintubation, and patient-related factors such as concomitant medical diseases. The contribution of underlying medical disease to laryngeal intubation injury was studied prospectively by sequential endoscopy from the time of tracheotomy. Diabetes mellitus, congestive heart failure, and a history of stroke or tuberculosis increased the likelihood of severe laryngeal
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5

Omori, Koichi, Tomoko Tsuji, Nobuhiko Isshiki, and Masaru Yamashita. "Bilateral Vocal Fold Paralysis and Adhesion in Anterior Spinal Artery Syndrome." Annals of Otology, Rhinology & Laryngology 111, no. 8 (2002): 680–83. http://dx.doi.org/10.1177/000348940211100804.

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The purpose of this report is to present a rare case of anterior spinal artery syndrome (ASAS) in which there proved to be a combined lesion of paralysis and adhesion. A 26-year-old woman with a history of ASAS complained of difficulty of tracheal decannulation. In 1988, she was intubated and underwent tracheotomy because of respiratory muscle weakness, and she was decannulated in 1990. In 1998, she had cesarean delivery under general anesthesia, and postdelivery dyspnea necessitated tracheotomy again. On her first visit to us, endoscopic examination revealed bilateral vocal fold immobility at
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6

Lombo, Catarina, Carlos Matos, and Rui Fonseca. "Primary laryngeal lymphoma: a diagnostic challenge." International Journal of Otorhinolaryngology and Head and Neck Surgery 8, no. 1 (2021): 77. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20214853.

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<p class="abstract">Lymphomas of head and neck constitute 5-15% of malignancies in this region. However, its primary occurrence at the larynx is exceedingly rare due to the paucity of lymphoid tissue. Here, we reported a case of a 41 year old male who presented with a 1 month history of hoarseness and odynophagia. The examination revealed right vocal cord palsy and an ipsilateral subglottic exudate, that was misdiagnosed as infectious disease. The lesion quickly progressed to airway obstruction, requiring a tracheotomy. Multiple biopsies under general anesthesia were needed before reachi
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Matioc, Adrian A. "An Anesthesiologist’s Perspective on the History of Basic Airway Management." Anesthesiology 124, no. 2 (2016): 301–11. http://dx.doi.org/10.1097/aln.0000000000000955.

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Abstract Basic airway management modern history starts in the early 18th century in the context of resuscitation of the apparently dead. History saw the rise and fall of the mouth-to-mouth and then of the instrumental positive-pressure ventilation generated by bellows. Pulmonary ventilation had a secondary role to external and internal organ stimulation in resuscitation of the apparently dead. Airway access for the extraglottic technique was to the victim’s nose. The bellows-to-nose technique was the “basic airway management technique” applicable by both medical and nonmedical personnel. Altho
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8

Ahmed, H., C. Ndiaye, M. W. Barry, et al. "A Rare Cause of Upper Airway Obstruction in a Child." Case Reports in Otolaryngology 2017 (2017): 1–3. http://dx.doi.org/10.1155/2017/2017265.

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Ventricular band cyst is a rare condition in children but can result in severe upper airway obstruction with laryngeal dyspnea or death. The diagnosis should be considered in any stridor in children with previous history of intubation or respiratory infections. We report a case of a 4-year-old girl, received in an array of severe respiratory distress, emergency endoscopy was done, and a large ventricular tape band cyst obstructing the air way was found. Complete excision was made, and postoperative prophylaxis tracheotomy was done. The postoperative course was uneventful with improvement of cl
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9

Zbar, Ross I. S., and Richard J. H. Smith. "Vocal fold Paralysis in Infants Twelve Months of Age and Younger." Otolaryngology–Head and Neck Surgery 114, no. 1 (1996): 18–21. http://dx.doi.org/10.1016/s0194-59989670277-2.

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Seventeen cases of unilateral or bilateral vocal fold paralysis were diagnosed in infants younger than 12 months from 1991 to 1994 at the University of Iowa Hospitals and Clinics. Eight (47%) children with left vocal fold paralysis had a history of prior thoracic surgery –- two to repair complex congenital anomalies and six to ligate a patent ductus arteriosus. During the study period, a total of 81 patent ductus arteriosus ligations were performed, yielding a 7.4% postoperative incidence of vocal fold paralysis. Seven (41%) children had idiopathic vocal fold paralysis (3 right, 1 left, 3 bila
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Bakkali, Hanae, Mouhcine Hoummadi, and Jawad Lahma. "Tonsillar Location of Skin Kaposi’s Sarcoma: A Case Report." Scholars Journal of Medical Case Reports 13, no. 06 (2025): 1345–50. https://doi.org/10.36347/sjmcr.2025.v13i06.011.

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We report a case of rare tonsillar location of Kaposi’s sarcoma observed in a non infected HIV man, who had a long history of skin kaposi’s disease during 28 years. Irradiation of skin lesions on lower limbs was succefully carried out with a dose of 30Gy on 10 fractions. Faced with the late appearance of dysphonia, we discover a locally advanced tonsillar location, and the PET- CT showed other distant supra and subdiaphragmatic lymph nodes involvements. After a first tracheotomy, the patient is treated by radiotherapy, 45 Gy on 25 fractions followed one month later by three cycles of chemother
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Eaton, Debbie A., Orval E. Brown, and David Parry. "Simple Technique for Tracheocutaneous Fistula Closure in the Pediatric Population." Annals of Otology, Rhinology & Laryngology 112, no. 1 (2003): 17–19. http://dx.doi.org/10.1177/000348940311200105.

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To review our experience with cauterization of persistent tracheocutaneous fistulas in children, we performed a retrospective review of patients who underwent cauterization of tracheocutaneous fistulas by the senior author (O.E.B.) from 1986 to 2001 in an academic, tertiary care children's hospital. We studied 13 pediatric patients ranging in age from 2.5 to 17.5 years of age at the time of surgery. Twelve patients underwent cauterization under endoscopic visualization. One patient underwent superficial cauterization of the tract without endoscopy. All patients had at least a 1-year history of
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12

Chauhan, Neha, Balaji Ramamourthy, Manjul Muraleedharan, and Ramandeep Singh Virk. "Laryngeal lymphangioma as a cause of respiratory distress in an adult with Down’s syndrome: an extremely rare presentation." BMJ Case Reports 14, no. 1 (2021): e240130. http://dx.doi.org/10.1136/bcr-2020-240130.

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A 32-year-old man with Down’s syndrome was referred to the ear, nose and throat (ENT) department in view of failed attempts at extubation, and subsequently, at decannulation of tracheotomy tube. He had previously required ventilatory support and had history of intubation for 1 week. A flexible fibre-optic laryngoscopy showed a smooth mass covering the laryngeal inlet which moved with respiration. Direct laryngoscopy under general anaesthesia revealed a smooth mucosa covered fleshy mass arising from the left aryepiglottic fold and arytenoid, obstructing the laryngeal inlet. The mass was removed
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13

Hota, Ashutosh, Arun Rath, and Diptiman Baliarsingh. "Open Safety Pin in Larynx: A Case Report and Review of Literature." An International Journal of Otorhinolaryngology Clinics 9, no. 1 (2017): 21–24. http://dx.doi.org/10.5005/jp-journals-10003-1255.

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ABSTRACT A foreign body in the respiratory tract is a serious event, and it needs urgent attention. It is important to know the type of foreign body with careful history taking. Usually, such cases come in pediatric age group due to accidental ingestion or inhalation. We present a case of 12-year-old female who presented with an impacted open safety pin lodged in the larynx. Its sharp end was upward in position and penetrated the subglottis and anterior commissure. A tracheotomy was done for securing airway, and the foreign body was removed with the help of rigid endoscope. The child had an un
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14

Meel, Rachna, and Meenakshi Wadhwani. "Shabbir Syndrome: Case Report of a Rare Disease." Nepalese Journal of Ophthalmology 11, no. 1 (2019): 105–7. http://dx.doi.org/10.3126/nepjoph.v11i1.25446.

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Purpose: To report a case of Laryngeal Onycho Cutaneous Syndrome in a 10 year old child presenting with an ocular surface mass.
 Methods: A 10 year old boy presented in the out-patient department with a painless mass in left eye. There was history of airway obstruction requiring tracheotomy in early childhood and recurrent skin ulcerations. Aslit lamp examination revealed fleshy mass arising from the supero-nasalconjunctiva of left eye. Systemic examination revealed ulcerative lesions on cheeks and ears with dystrophic nails in hands and feet.
 Results: The ocular surface lesion was
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15

Amin, Shaunak N., Jennifer P. Rodney, and Alexander Gelbard. "Open Airway Surgery in a Paraplegic: The Importance of an Adequate Cough." Annals of Otology, Rhinology & Laryngology 128, no. 12 (2019): 1194–97. http://dx.doi.org/10.1177/0003489419866471.

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Objectives: To describe a case of open airway surgery with postoperative respiratory complications in a paraplegic woman and to review the unique respiratory physiology seen in patients with a history of cervical or thoracic spinal cord injury (SCI). Methods Case report and literature review. Results: We describe the case of a 25-year-old paraplegic who developed tracheal stenosis after tracheotomy, eventually requiring tracheal resection and re-anastomosis. Her postoperative course was complicated by mucus plugging and severe atelectasis, necessitating reintubation. After extubation, the pati
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16

Bawa, Rohit, Hassan H. Ramadan, and Stephen J. Wetmore. "Bilateral Vocal Cord Paralysis with Shy-Drager Syndrome." Otolaryngology–Head and Neck Surgery 109, no. 5 (1993): 911–14. http://dx.doi.org/10.1177/019459989310900521.

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Shy-Drager syndrome consists of progressive autonomic nervous system failure with Parkinson's disease-like symptoms and orthostatic hypotension. It can also result in airway compromise from bilateral vocal cord paralysis. Fewer than 30 cases of severe bilateral vocal cord paresis or paralysis associated with the Shy-Drager syndrome have been reported in the English literature. We present a case of a 72-year-old man who had a 2-year history of orthostatic hypotension, neurogenic bladder, impotence, anhydrosis, and extremity weakness and paresthesias. Hoarseness and dyspnea with stridor develope
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17

Donovan, Donald T., Daniel J. Franklin, Judith J. Owens, et al. "Life-Threatening Presentations of Fibrovascular Esophageal and Hypopharyngeal Polyps." Annals of Otology, Rhinology & Laryngology 103, no. 11 (1994): 838–42. http://dx.doi.org/10.1177/000348949410301102.

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Giant fibrovascular polyps of the esophagus and hypopharynx are benign tumors of the upper digestive tract Although a rare cause of asphyxiation, laryngeal impaction by a regurgitated polyp of the esophagus may be the initial symptom that brings the patient to request medical attention. Two new cases of giant fibrovascular polyps with dramatic and potentially life-threatening presentations illustrate the unpredictable behavior of these unusual tumors. Both patients presented to the emergency center with a history of coughing and eructation followed by temporary airway obstruction that was reli
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18

Chen, Hui, Yang Guo, Cai Li, and Liang Zhou. "Paraglottic space schwannoma: a case report and literature review." Journal of International Medical Research 50, no. 9 (2022): 030006052211224. http://dx.doi.org/10.1177/03000605221122497.

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Neurogenic tumors located in the larynx are extremely rare. Among them, schwannoma is a benign encapsulated tumor originating from Schwann cells, which form nerve fiber sheaths in the peripheral nervous system. We herein report a case of a schwannoma arising from a rare subsite of the larynx and review the literature on laryngeal schwannoma. The case involved a woman with a 1-month history of globus pharyngeus and dysphagia without dysphonia. Rigid laryngoscopy and magnetic resonance imaging showed a large submucosal bulge toward the medial wall of the right pyriform fossa, pushing the right f
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19

Ababou, Mounir, Hicham El Maaroufi, Adnane Hammani, et al. "Acute Laryngeal Dyspnea as the First Presentation of Mantle Cell Lymphoma: A Case Report and Review of the Literature." Case Reports in Hematology 2020 (September 9, 2020): 1–4. http://dx.doi.org/10.1155/2020/8818270.

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Introduction. Acute laryngeal dyspnea is a life-threatening emergency, and the causes in adults are most often laryngeal tumors or inflammatory edema. Lymphoma of the larynx and especially the mantle cell type is extremely rare. Case Presentation. We report a case of a 43-year-old woman with no particular pathological history. She presented with progressive dyspnea which has evolved towards an inspiratory bradypnea that worsened until she ultimately required an emergency tracheotomy. Biopsies revealed mantle cell lymphoma. The patient has been staged IVB MIPI 6, and she was treated by immunoch
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Carnate, Jose M., and Audie G. Silva. "Granular Cell Tumor Presenting as a Tracheal Mass in a 17-year-old Female." Philippine Journal of Otolaryngology-Head and Neck Surgery 23, no. 1 (2008): 39–40. http://dx.doi.org/10.32412/pjohns.v23i1.777.

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Granular cell tumors involving the trachea are rare. We present the case of a seventeen year old female with a one year history of gradually worsening dyspnea necessitating a tracheotomy. A suprastomal intraluminal tracheal mass was excised. Histologic sections (Figure 1) show a poorly circumscribed neoplasm infiltrating through the tracheal cartilage. It is composed of polygonal to somewhat elongated tumor cells that have small, dark nuclei. The cytoplasm is ample, eosinophilic and strikingly granular in quality. The cell borders are ill-defined creating a `syncytial’ pattern of dark nuclei s
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Kane, Paula M. "“She offered herself up”: The Victim Soul and Victim Spirituality in Catholicism." Church History 71, no. 1 (2002): 80–119. http://dx.doi.org/10.1017/s0009640700095160.

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A teenage Catholic girl lies immobilized in her bed in Worcester, Massachusetts, her dark hair gathered in pink satin ribbons, her lacy nightgown spread neatly around her. The pleasing effect of a damsel in a pre-Raphaelite painting is broken by the sight of a tracheotomy tube in her neck attached to a ventilator, and a feeding tube in her stomach. For the last six years the American media has provided glimpses into the curious vegetative existence of Audrey Santo (1984–), who has lain in a coma-like state since a swimming pool accident at the age of three. Despite the girl's lack of conscious
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Pradeep, Pallavi, and Mohammed Hussain Kazi. "Thyroid Storm: A Dreaded Complication of Percutaneous Tracheostomy." Journal of the Endocrine Society 5, Supplement_1 (2021): A963—A964. http://dx.doi.org/10.1210/jendso/bvab048.1970.

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Abstract Background: Thyroid gland may be manipulated during tracheostomy. Although uncommon, this may result in potentially life-threatening thyroid storm especially in patients with underlying thyroidal illness. Plasmapheresis maybe used as a treatment modality for these patients. Clinical Case: A 65-year-old Hispanic male was admitted to the hospital for acute exacerbation of heart failure and pneumonia. Medical history was significant for atrial fibrillation. He had been on amiodarone for 2 years, which was discontinued 2 months ago when he was diagnosed with amiodarone indued thyrotoxicos
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23

Idoubba, S., B. Hemmaoui, J. Oubenjah, et al. "OBSTRUCTIVE LARYNGEAL DYSPNEA REVEALING A LARGE SUPRAGLOTTIC FIBROLIPOMA: A CASE REPORT." International Journal of Advanced Research 13, no. 07 (2025): 85–89. https://doi.org/10.21474/ijar01/21270.

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Background: Laryngeal fibrolipomas are exceptionally rare benign tumors composed of mature adipose and fibrous tissue. Their insidious growth and nonspecific symptoms can lead to delayed diagnosis and potential airway compromise. Case Presentation: We report the case of a 56-year-old male with a history of chronic smoking who presented with progressive dysphonia, dysphagia, and inspiratory dyspnea over nine months. Nasofibroscopy revealed a supraglottic mass obstructing the airway. CT imaging demonstrated a well-circumscribed, fat-density lesion suggestive of a fibrolipoma. Due to the risk of
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24

Paczkowski, Konrad, Ireneusz Haponiuk, Maciej Chojnicki, and Grażyna Brzezińska-Rajszys. "Hybrid Interventional Treatment of Iatrogenic Innominate Artery Aneurysm in a Child." Heart Surgery Forum 19, no. 4 (2016): 203. http://dx.doi.org/10.1532/hsf.1544.

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An iatrogenic aneurysm of an innominate artery is an extremely rare complication, especially in children. Nevertheless, this pathology was diagnosed in a child given palliative care with chronic respiratory insufficiency and a history of encephalitis requiring permanent ventilation at home via a tracheal tube.<br />A nine-year-old girl with colitis ulcerosa and a history of hemorrhagic encephalitis, with chronic home ventilation therapy, was admitted in an emergency setting because of massive bleeding from the upper respiratory tract and the area surrounding the tracheotomy. Repeated tam
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25

A, Kassambara,, Guindo, S. O, Coulibaly, A, et al. "Giant Odontogenic Myxoma of the Maxillary: A Rare Entity." Scholars Journal of Dental Sciences 12, no. 01 (2025): 8–12. https://doi.org/10.36347/sjds.2025.v12i01.002.

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Introduction: Maxillary odontogenic myxoma is a locally invasive benign mesenchymal tumor. The objective of this case observation was to discuss the difficulties related to the management of a case of giant maxillary odontogenic myxoma. Observation: This was a 32-year-old patient who consulted in the stomatology and maxillofacial surgery department of the CHU-CNOS Pr HT of Bamako for a swelling of the left hemiface evolving for 3 years with deterioration of the general condition. She has no particular medical or surgical history. On physical examination, there was a large swelling of the left
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Shushan, S., U. Cinamon, D. Levy, M. Sokolov, and Y. Roth. "Laryngeal cancer in acquired immunodeficiency syndrome." International Journal of STD & AIDS 20, no. 8 (2009): 582–84. http://dx.doi.org/10.1258/ijsa.2008.008345.

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With improved survival, more AIDS patients, especially heavy smokers and alcohol abusers, may be confronted with laryngeal squamous cell carcinoma. Since curative treatment may require aggressive combined therapy, these patients, often suffering from immunosupression and poor general condition, present unique therapeutic challenges. The objective of the study was to describe treatment dilemmas. This case report presents a detailed description of an AIDS patient with carcinoma of the larynx. A patient with T3N0M0 laryngeal carcinoma and AIDS underwent tracheotomy and biopsy, followed by severe
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Rathod, Indutai G., Vishal H. Pawar, and Sujit M. Shivasharan. "An interesting case of extraluminal migrating fish bone." International Journal of Otorhinolaryngology and Head and Neck Surgery 10, no. 1 (2024): 156–58. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20240081.

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Hypopharyngeal and oesophageal foreign bodies are usually intraluminal but sharp foreign bodies can get impacted submucosally or extraluminally due to inadvertent attempt of removal by patient. Foreign body impaction is a common condition in Asian populations, with fish bone being the most common, often migrating to the lateral neck space or related organs. This case report emphasizes the significance of proper history and awareness among clinicians about the migration of fish bones, aiming to prevent diagnosis delays and potential complications. The present case depicts an unusual presentatio
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Vaughn, John L., Jared M. Moore, and Spero R. Cataland. "Acute Systolic Heart Failure Associated with Complement-Mediated Hemolytic Uremic Syndrome." Case Reports in Hematology 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/327980.

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Complement-mediated hemolytic uremic syndrome (otherwise known as atypical HUS) is a rare disorder of uncontrolled complement activation that may be associated with heart failure. We report the case of a 49-year-old female with no history of heart disease who presented with microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. Given her normal ADAMSTS13 activity, evidence of increased complement activation, and renal biopsy showing evidence of thrombotic microangiopathy, she was diagnosed with complement-mediated HUS. She subsequently developed acute hypoxemic respirato
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Wójtowicz, Piotr, Tomasz Szafarowski, Ewa Migacz, and Antoni Krzeski. "Recurrent Laryngeal Edema Imitating Angioedema Caused by Dislocated Screw after Anterior Spine Surgery." Case Reports in Otolaryngology 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/749463.

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The anterior cervical spine surgery is a common procedure to stabilize vertebrae damaged by various diseases. The plates and screws are usually used in the spine fixation. This kind of instrumentation may detach from the bones which is a rare but well-known complication. A 77-year-old male presented to the otorhinolaryngology department with throat pain, choking, and dysphagia. At first the angioedema was diagnosed and he was treated conservatively. The endoscopy revealed laryngeal edema, being more defined on the right side with right vocal fold paresis. CT scans showed the stabilizing plate
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30

P, Gamba, De Franciscis G, Pignatelli U, Licursi G, Gentile L, and Moz U. "Parapharyngeal Abscess: A Model of Continuity and Contiguity Deep-Neck Space Infections: A Diagnostic Dilemma!" Annals of Otolaryngology and Rhinology 11, no. 1 (2024): 1–4. http://dx.doi.org/10.47739/2379-948x.otolaryngology.1325.

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The aims of the present case report were to review, computed tomography (CT) scans, clinical signs, treatment, and outcome of parapharyngeal space infections. These infections remain an important health problem with significant risks of morbidity and mortality. The term parapharyngeal abscess or infection is composed of two different disorders: infection located in the posterior part of the PPS with no invasion into the parapharyngeal fat and the second disorder is when the infection involving the parapharyngeal fat may be termed parapharyngeal abscess or deep neck abscess. Diffusion into the
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Kottaram, Philip John, S. Vinayababu, and Khaji Mohammed Tanveer. "Diphtheria Resurgence: Where did We fail?" International Journal of Head and Neck Surgery 4, no. 3 (2013): 137–39. http://dx.doi.org/10.5005/jp-journals-10001-1163.

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ABSTRACT Objective This report aims at highlighting the persistence of diphtheria in India and the need for better vaccine coverage of both primary as well as booster doses and accessibility of antidiphtheric serum (ADS) at all tertiary medical centers. Case report An 11-year-old girl, previously unimmunized against diphtheria, presented with history of fever, cough, difficulty in swallowing and change in voice within 1 week duration. Examination revealed bilaterally enlarged tonsils with a grayish white patch over them. A provisional diagnosis of faucial diphtheria and the patient was started
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Wang, Yaqi, Longqing Ding, Jiahui Liu, et al. "Giant laryngeal neuroendocrine neoplasm causing airway obstruction: A case report and literature review." Medicine 103, no. 22 (2024): e38382. http://dx.doi.org/10.1097/md.0000000000038382.

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Rationale: Laryngeal neuroendocrine neoplasm (NEN) is a rare and heterogeneous disease that originates from neuroendocrine cells. It mainly occurs in middle-aged and elderly men. Due to the lack of specific clinical and imaging manifestations, diagnosis and treatment of the disease pose a challenge. Therefore, a consensus on the diagnosis and treatment of the disease is necessary. By discussing this case, we will be able to gain further insight into laryngeal NEN and will be able to provide some recommendations for the future management of this rare disease. Patient concerns: A 67-year-old man
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Suria, Stephanie, Raphaëlle Galy, Lauriane Bordenave, et al. "High Frequency Jet Ventilation or Mechanical Ventilation for Panendoscopy for Cervicofacial Cancer: A Retrospective Study." Journal of Clinical Medicine 12, no. 12 (2023): 4039. http://dx.doi.org/10.3390/jcm12124039.

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Introduction—the upper airway panendoscopy, performed under general anesthesia, is mandatory for the diagnosis of cervicofacial cancer. It is a challenging procedure because the anesthesiologist and the surgeon have to share the airway space together. There is no consensus about the ventilation strategy to adopt. Transtracheal high frequency jet ventilation (HFJV) is the traditional method in our institution. However, the COVID-19 pandemic forced us to change our practices because HFJV is a high risk for viral dissemination. Tracheal intubation and mechanical ventilation were recommended for a
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Li, Da, Shu-Yu Hao, Zhen Wu, Li-Wei Zhang, and Jun-Ting Zhang. "Primary medulla oblongata teratomas." Journal of Neurosurgery: Pediatrics 14, no. 3 (2014): 296–300. http://dx.doi.org/10.3171/2014.6.peds1423.

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Medulla oblongata teratomas are rare. The authors report 2 new cases of teratomas that occurred exclusively in the medulla oblongata. The first case was in a 9-year-old boy who presented with a 6-month history of neck pain and repeated paroxysmal vomiting. Based on preoperative radiographic findings, the initial diagnosis was of an intraaxial medulla oblongata hemangioblastoma. Intraoperatively, the cystic component of the tumor was gray, gelatinous, and soft in consistency. The solid component was light pink, rubbery, and nodular in appearance, with an identifiable boundary. The lesion was co
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de Groot, J. W. B., B. A. Zonnenberg, P. Quarles van Ufford-Mannesse, et al. "A Phase II Trial of Imatinib Therapy for Metastatic Medullary Thyroid Carcinoma." Journal of Clinical Endocrinology & Metabolism 92, no. 9 (2007): 3466–69. http://dx.doi.org/10.1210/jc.2007-0649.

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Abstract Context: Medullary thyroid carcinoma (MTC) metastasizes early in its clinical course. No effective systemic therapy is available. Generally (somatic or germline), mutations in the rearranged during transfection gene are considered essential in the pathogenesis of MTC. Objective: We investigated imatinib, a tyrosine kinase inhibitor, as a potential treatment in patients with disseminated MTC. Design: A phase II study was initiated using 600 mg imatinib daily with a possible dose increase to 800 mg in case of progression. Standard Response Evaluation Criteria in Solid Tumors were used u
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Aras, Berke, Canan Çulha, Alp Varol, and Evren Yaşar. "The effect of etiological and clinical characteristics on the rehabilitation process and functional gains in pediatric severe acquired brain injury." Turkish Journal of Physical Medicine and Rehabilitation 71, no. 1 (2024): 74–82. https://doi.org/10.5606/tftrd.2024.14479.

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Objectives: The aim of this study was to investigate the etiological and clinical characteristics of pediatric patients with severe acquired brain injury and their effects on rehabilitation outcomes. Patients and methods: A total of 67 pediatric patients (39 males, 28 females; mean age: 9.7±4.8 years; range, 3 to 18 years) who were hospitalized due to severe acquired brain injury between March 2020 and October 2021 were retrospectively analyzed. The patients were classified in five different groups according to the etiology: traumatic brain injury, anoxic brain injury (ABI), cerebrovascular ac
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Wang, Xiaojing, Rongguo Yu, Xiuling Shang, et al. "Multicenter Study of Tetanus Patients in Fujian Province of China: A Retrospective Review of 95 Cases." BioMed Research International 2020 (March 17, 2020): 1–5. http://dx.doi.org/10.1155/2020/8508547.

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Background. Tetanus is a life-threatening disease in developing countries and is accompanied by a high mortality rate. Although China is the world’s largest developing country, there have been few clinical studies on tetanus in China. The purpose of this study was to investigate the epidemiology, incidence, and management of tetanus in Fujian Province and to understand the current treatment and prognosis of tetanus patients. Methods. This was a retrospective, multicenter observational study of patients who presented with a clinical diagnosis of tetanus at 5 general hospitals in Fujian from Jan
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Oliveira, Acary Souza Bulle, and Roberto Dias Batista Pereira. "Amyotrophic lateral sclerosis (ALS): three letters that change the people's life. For ever." Arquivos de Neuro-Psiquiatria 67, no. 3a (2009): 750–82. http://dx.doi.org/10.1590/s0004-282x2009000400040.

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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting the motor nervous system. It causes progressive and cumulative physical disabilities in patients, and leads to eventual death due to respiratory muscle failure. The disease is diverse in its presentation, course, and progression. We do not yet fully understand the cause or causes of the disease, nor the mechanisms for its progression; thus, we lack effective means for treating this disease. Currently, we rely on a multidisciplinary approach to symptomatically manage and care for patients who have ALS. Although amyotro
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Zonnenberg, B. A., T. Links, P. Quarles van Uffort, C. Lips, J. De Groot, and E. Voest. "Phase-2 study of imatinib in metastasized medullary thyroid carcinoma." Journal of Clinical Oncology 24, no. 18_suppl (2006): 15500. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.15500.

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15500 Background: Medullary thyroid carcinoma (MTC) is a relatively rare tumor that metastasizes to regional lymph nodes, lung, liver and bone. When surgery is no longer a curative treatment option, no effective systemic therapy is currently available. In most cases a (somatic or germline) mutation in the RET (REarranged during Transfection) gene is considered to be an essential step in the pathogenesis of MTC. Imatinib is an oral inhibitor of several protein-tyrosine kinases including RET kinase. It has shown to be an effective drug in chronic myeloid leukemia and gastrointestinal stromal tum
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Feeley, C., and E. Chasens. "0948 Sleep Quality, Depressive Symptoms, and Stress in Maternal Caregivers of Young Children with Bronchopulmonary Dysplasia." Sleep 43, Supplement_1 (2020): A360. http://dx.doi.org/10.1093/sleep/zsaa056.944.

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Abstract Introduction Maternal caregivers of young children with a chronic illness, like bronchopulmonary dysplasia (BPD), often report increased levels of stress and depressive symptoms, as well as poor quality of sleep. Caregiving duties are time-intensive and extend into the nighttime hours. The purpose of this study is to examine sleep, depressive symptoms, and stress in maternal caregivers of young children with BPD, as well as determine if depressive symptoms is a mediating variable between sleep quality and stress. Methods 61 maternal caregivers (mean age 29 yrs) of young children with
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1Hamza, Hussain Bangash 2Misha Anam 3Zahra Batool Manzoor 4Soumyadeep Sikdar. "An Unusual Case of Fractured Tracheostomy Tube as a Foreign Body in Right Main Bronchus: A Case Report." International Journal of Medical Science in Clinical Research and Review 05, no. 04 (2022): 206–9. https://doi.org/10.5281/zenodo.6988031.

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<strong>ABSTRACT</strong> In this case report, we have discussed a case of a 10-year-old boy presented with one day history of progressively worsening respiratory distress, cough, and stridor. Patient was a follow-up case of GBS with tracheostomy tube in situ. This time, he presented with fractured PVC tracheostomy tube from the junction of neck plate and tubular tracheal piece. The dislodged tubular part of the tracheostomy tube had gotten stuck in the trachea and right main bronchus at the level of the carina which was confirmed by radiological investigation. The procedure of the foreign bod
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Cochin, Valérie, Erwan De-Mones-Del-Pujol, Laurence Digue, et al. "Induction chemotherapy (IC) with EXTREME study regimen for locally advanced head and neck cancer (LAHNC) frail patients." Journal of Clinical Oncology 35, no. 15_suppl (2017): e17564-e17564. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e17564.

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e17564 Background: IC with TPF (docetaxel, cisplatin, 5FU) in LAHNC is limited to fit patients (pts). We conducted a retrospective cohort study to evaluate the use of EXTREME regimen (platinum, 5FU, cetuximab) as IC in LAHNC frail pts. Methods: Retrospective analysis of all consecutive pts with unresectable LAHNC treated with EXTREME regimen with or without 5FU as IC from two French centers from 2008 to 2015. We evaluated the rate of realization of the complete sequence (at least 2 cycles of IC and all radiation courses). Tolerance and efficacy, including clinical benefice, median progression
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Schlick, Konstantin, Martin Pichler, Sonja Reitter, et al. "Histiocytis Sarcoma-Targeted Therapy: Novel Therapeutic Options? A Series of 4 Cases." Blood 118, no. 21 (2011): 5005. http://dx.doi.org/10.1182/blood.v118.21.5005.5005.

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Abstract Abstract 5005 Case 1: A 23-year old man presented with a newly diagnosed Histiocytic Sarcoma (HS) of the neck. Tracheotomy had to be performed due to a massive swelling of the neck and pharynx. Chemotherapy was initiated in combination with local irradiation therapy with the aim of stabilization of the fulminate disease course.To gain further insight in the tumour's biology an extensive immunohistochemistry exploration was done. A positive reaction with antibodies (AB) against PDGFRalpha and VEGFR2 and VEGFR3 was detected with variable staining intensities and number of tumor cells. A
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Pascual, Ma Victoria P. "Stridor at Birth: Congenital Laryngeal Web." Philippine Journal of Otolaryngology-Head and Neck Surgery 30, no. 2 (2015): 59–61. http://dx.doi.org/10.32412/pjohns.v30i2.359.

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Laryngeal web is a rare entity, constituting 5% of all congenital laryngeal lesions, with a reported incidence of 1 in 10,000.1 It usually presents with stridor in childhood, but can be discovered in asymptomatic adults under anesthesia and is associated with failed intubations.2 We present the case of a newborn with stridor and respiratory distress due to laryngeal web.&#x0D; &#x0D; CASE REPORT&#x0D; &#x0D; A 47-day-old boy was referred to our institution for stridor. He was spontaneously born term at 40 3/7 weeks gestational age to a 26-year-old G2P2 (2002). Birth weight was 3104 grams and m
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David, Reylan B., and William L. Lim. "Congenital Bilateral Vocal Fold Paralysis in a Two-Year-Old Girl." Philippine Journal of Otolaryngology-Head and Neck Surgery 29, no. 1 (2014): 30–32. http://dx.doi.org/10.32412/pjohns.v29i1.461.

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Vocal fold paralysis is an otolaryngologic disorder that is more prevalent in the adult population. Its occurrence in children has been documented in the literature. We report a case of congenital bilateral vocal fold paralysis and discuss the issues surrounding its ultimate diagnosis and management.&#x0D; &#x0D; CASE REPORT&#x0D; Three months prior to consult, a five–year-old girl started to have noisy (whistling), difficult breathing lasting throughout the day and becoming louder if she cried. She had no cough, colds, fever, or voice changes. Suspecting asthma, an attending pediatrician at a
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Andrae, Hannah, Thomas Musholt, Hauke Lang, and Peter Grimminger. "PS02.147: MANAGEMENT OF A SIMULTANEOUS HIGH ESOPHAGO-TRACHEAL FISTULA CAUSED BY ESOPHAGEAL STENT DUE TO ANASTOMOTIC LEAKAGE AFTER IVOR-LEWIS ESOPHAGECTOMY: A CASE REPORT." Diseases of the Esophagus 31, Supplement_1 (2018): 162. http://dx.doi.org/10.1093/dote/doy089.ps02.147.

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Abstract Background Esophagotracheal perforation is a very severe complication. However, an esophagotracheal perforation caused due to an esophageal stent after anastomotic leakage after ivor-lewis resection, is even more complex and associated with high mortality. Therefore we present a case how we managed a high esophagotracheal perforation and anastomotic leakage after ivor-lewis resection of esophageal cancer, prior treated with neoadjuvant radiochemotherapy. Methods Case report A 71-year old patient was transferred to our center due to an esophagotracheal perforation at the proximal stent
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Marino, Melanie Y., and Antonio H. Chua. "Congenital Saccular Cyst of the Larynx." Philippine Journal of Otolaryngology-Head and Neck Surgery 23, no. 1 (2008): 35–36. http://dx.doi.org/10.32412/pjohns.v23i1.773.

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&#x0D; Congenital saccular cysts of the larynx are a rare cause of airway obstruction in the neonatal population. Symptoms are non-specific and common to other causes of laryngeal obstruction. Prompt recognition and management is important because of the high mortality associated with undiagnosed conditions.&#x0D; CASE&#x0D; A 2-month old female was seen at the Pediatric emergency room because of breathing difficulty. She had productive cough 2 days prior, accompanied by labored breathing, vomiting and poor appetite. She was admitted at the Pediatric ICU with a diagnosis of acute bronchiolitis
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Onofre, Rubiliza DC. "Parapharyngeal Neurofibroma in a Pediatric patient." Philippine Journal of Otolaryngology-Head and Neck Surgery 25, no. 1 (2010): 38–40. http://dx.doi.org/10.32412/pjohns.v25i1.661.

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Primary tumors of the parapharyngeal area are rare and account for 0.5% of all head and neck tumors.1,2 Among these, 80% are benign while 20% are malignant.2 Next to schwannomas, neurofibromas are the second most commonly encountered primary tumor of nerve sheath origin in the parapharyngeal space but incidence and prevalence rates have not been documented among pediatric patients.3,4 Plexiform neurofibromas in particular pose a surgical challenge in pediatric patients. Careful preoperative planning, advanced surgical techniques, and vigilant postoperative care result in minimal morbidity and
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Artates, Anne Margaux V., and Melfred L. Hernandez. "Frontolateral Laryngectomy with Imbrication Laryngoplasty for Stage I Glottic Carcinoma." Philippine Journal of Otolaryngology-Head and Neck Surgery 27, no. 1 (2012): 31–34. http://dx.doi.org/10.32412/pjohns.v27i1.553.

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Good prognosis has been associated with early detection of Squamous Cell Carcinoma of the larynx. The patient’s choice for any treatment modality depends highly on the cure rate, larynx preservation rate, post-treatment voice quality, morbidity, and treatment cost.1 Regardless of which stage of disease, the choice of treatment centers mainly on the maintenance of quality of life and minimal adverse effects.&#x0D; &#x0D; CASE REPORT&#x0D; &#x0D; A 56-year-old male presented with a 9-month history of intermittent hoarseness with occasional low-grade fever. A local private physician diagnosed pul
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Reyes-Quintos, Maria Rina T. "Pediatric Rigid Bronchoscopy for Foreign Body Removal." Philippine Journal of Otolaryngology-Head and Neck Surgery 24, no. 1 (2009): 39–41. http://dx.doi.org/10.32412/pjohns.v24i1.719.

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Rigid bronchoscopy is a procedure that is performed in order to directly visualize the upper and lower airway, and is carried out for either a diagnostic or therapeutic purpose. Suspected foreign body (FB) aspiration is the most common indication for performing this procedure in the pediatric age group at the Philippine Children’s Medical Center where a recent census (May 2008 to April 2009) showed that of 21 cases where rigid bronchoscopy was performed, 10 were for suspected FB aspiration. A review of 101 cases in the same institution showed that the average age of patients with FB aspiration
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