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1

Phooko, Puleng M. (Puleng Mpopi). "Nutritional factors associated with oral lesions in HIV disease and TB infection." Thesis, Stellenbosch : Stellenbosch University, 2003. http://hdl.handle.net/10019.1/53528.

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Thesis (Mnutr)--University of Stellenbosch, 2003.<br>ENGLISH ABSTRACT: Problem Definition: In the context of HIV/AIDS malnutrition is almost universal among children, and of the adverse effects of Protein Energy Malnutrition, the most frequent seems to be the occurrence of opportunistic infections with micro-organisms such as oral Candida. Objective: The aim of this study was to determine the nutritional status of children with oral complications in relation to HIV/AIDS as well as the effects of the oral lesions on nutritional status. Subjects/setting: The subjects of study were 24 chil
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2

Bistline, Kathryn Lou. "Does the inclusion of the cost and burden of adverse drug reactions associated with drug-resistant TB treatment affect the incremental cost-effectiveness of new treatment regimens? A case study from the introduction of bedaquiline in South Africa National TB Programme." Doctoral thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/28441.

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South Africa has one of the world’s highest burdens of TB, HIV/TB co-infection, and drug-resistant TB. Second-line TB treatment is less effective, more expensive, and more toxic than treatment for drug-sensitive TB. Nearly 1 in every 5 persons who starts treatment for drug-resistant TB in South Africa will die; 1 in every 3 persons who survives treatments experiences permanent, profound hearing loss. For decades there was little progress in TB research, however, and so treatment with old regimens continued despite safety concerns. In 2012 the US and European regulatory authorities approved a n
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3

Tadokera, Rabecca. "Investigating the socio-economic and epidemiological risk factors associated with TB transmission in a high TB and HIV burdened community in Cape Town, South Africa." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/28146.

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Background: While several studies have studied the associations between biological factors such as HIV-status with TB transmission or clustering, our understanding of the associations between TB transmission and socio-economic risk factors for TB remains incomplete. More studies are required to enhance our understanding, and hence inform targeted interventions to curb TB transmission, particularly in high burden communities. This study aimed to explore the associations between TB transmission and socio-economic risk factors in one such high TB and HIV burdened community. Methods: A cross-secti
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4

Mudzengi, Don Lawrence. "Factors associated with concurrent consultation of primary health care clinics and other providers by TB patients and HIV patients." Diss., University of Pretoria, 2015. http://hdl.handle.net/2263/53033.

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Introduction. Concurrent use of public sector and other healthcare facilities by adult persons seeking treatment for human immunodeficiency virus (HIV) and/ or tuberculosis (TB) has been shown to lead to poorer health outcomes for such patients. Apart from structural factors (e.g. service standards), demographic and personal factors may also influence patients to use private health services concurrently with public sector services for these two diseases. Aim. The Aim of this analysis was to explore demographic and personal factors associated with concurrent use of public and private hea
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5

Hickman, John-Henry. "Exploring how Health-related Quality of Life (HRQOL) is experienced among patients living with HIV associated TB in Khayelitsha, South Africa." Master's thesis, Faculty of Health Sciences, 2020. http://hdl.handle.net/11427/32225.

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Health-related quality of life (HRQOL) is a construct that has received attention in research for nearly four decades. However, renewed interest in this field came about with advances in medical technology and health policies. Better treatment options and policies, which enables greater access to health care, have improved health outcomes, such as leading to an extension in life expectancy. This rings particularly true for Human Immunodeficiency virus (HIV) and associated illnesses such Tuberculosis (TB). However, improvements in health outcomes are not necessarily accompanied by satisfactory
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6

Denis, Marie F. "Extrapulmonary tuberculosis in HIV-positive and HIV-negative children in Haiti : a hospital-based Investigation." [Tampa, Fla] : University of South Florida, 2005. http://purl.fcla.edu/usf/dc/et/SFE0001404.

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7

Deffur, Armin. "The transciptomic landscape of HIV-TB." Doctoral thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/3377.

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Includes abstract.<br>Includes bibliographical references.<br>The thesis consists of four main parts. In Part 1 of this thesis I provide a broad overview of HIVTB with an emphasis on systems approaches followed by an overview of a systems-level study aiming at addressing hypotheses relating to transcriptional differences in active tuberculosis and HIV-1 infection, measured in blood and the site of disease in tuberculous pericarditis. The final chapter in this part describes the methods used to generate and analyse the systems-level data, with emphasis on microarray data generation and analysis
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8

Dinic, Lana. "Molecular Diagnosis of TB and MDR-TB in HIV-Coinfection in Nigeria." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10387.

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Tuberculosis (TB) is the most common opportunistic infection in HIV-infected patients and the emergence of drug-resistant tuberculosis (DR-TB) is a growing problem in resource-limited settings (RLS). TB diagnosis in most RLS still depends on smear microscopy for acid-fast bacilli (AFB) while adequate infrastructure for testing drug sensitivity is unavailable. However, molecular diagnostics that detect Mycobacterium tuberculosis (Mtb) DNA and its genetic markers of drug resistance were recently developed. In this thesis I describe the use of a molecular diagnostic, Genotype MTBDRplus, for c
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9

Kolotylo, T. R. "Clinical features of combined HIV/TB infection." Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18885.

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10

Kajunguri, Damian. "Modelling the impact of TB superinfection on the dynamics of HIV-TB coinfection." Thesis, Stellenbosch : University of Stellenbosch, 2009. http://hdl.handle.net/10019.1/4070.

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Thesis (MSc (Mathematics))--University of Stellenbosch, 2009.<br>ENGLISH ABSTRACT: In this thesis, a mathematical model describing the interaction between HIV and TB in the presence of TB superinfection is presented. The model takes into account two strains of Mycobacterium tuberculosis (MTB), where one strain is drug-sensitive and the other is resistant to at least one of the first-line anti-tuberculosis drugs. The impact of TB superinfection on the incidence and prevalence of TB in HIV-negative and HIVTB coinfected individuals is evaluated. Various control measures such as condom use,
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11

Ansa, Gloria Akosua. "Integration of tuberculosis (TB) and HIV services in Ghana." Thesis, University of Leeds, 2011. http://etheses.whiterose.ac.uk/2419/.

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Integration of health services involves managing services to enhance quality for patient needs that cut across multiple services, providers and settings. The rapid growth of human immunodeficiency virus (HIV) has increased tuberculosis (TB) cases, and TB/HIV integration offers a unified strategy for control. This study evaluated TB/HIV integration in Ghana. The three sites evaluated applied varying degrees of integration. A mixed methods approach comprised an uncontrolled before-and-after study involving 1330 TB cases, and qualitative interviews with 29 providers and patients. TB treatment suc
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12

Sattar, Shahra. "Influence of HIV, smoking and hyperglycaemia on the reporting of TB symptoms in a TB prevalence survey." Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/3065.

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Includes abstract.<br>Includes bibliographical references.<br>Finding and treating cases [of tuberculosis] in the community before they present to health facilities, a strategy known as active-case-finding is gaining momentum as a way to decrease the infectious pool. This can be achieved through door-to-door community surveys using a TB symptom-screening questionnaire, and is an economical and practical tool to employ in poor, high burden areas. However, unlike for the high risk group of people infected with HIV, there is a lack of evidence supporting the adaptation of a symptom screening tool
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13

Cornick, Ruth. "'You must tune your TB programme well...' : integrating TB, HIV and ARV care in Cape Town primary care setting." Master's thesis, University of Cape Town, 2007. http://hdl.handle.net/11427/9328.

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Includes bibliographical references (leaves 86-91).<br>This study occurred in the context of three problems that have arisen within the South African HIV/AIDS crisis: the prevalent HIV and tubertulosis (TB) co-epidemic, the concern that antiretroviral (ARV) provision might compromise the existing TB control programme, and that the Western Cape's current limited vertical model of ARV roll-out will soon reach capacity. This study evaluated whether and how TB control changed following ARV introduction in a Cape Town primary care TB clinic and explored the process of integration of the TB and ARV
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14

Pretorius, Carel Diederik. "An investigation into joint HIV and TB epidemics in South Africa." Thesis, Stellenbosch : Stellenbosch University, 2009. http://hdl.handle.net/10019.1/1166.

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Thesis (PhD (Physics))--Stellenbosch University, 2009.<br>ENGLISH ABSTRACT: This dissertation investigates certain key aspects of mathematical modeling of HIV and TB epidemics in South Africa with particular emphasis on data from a single well-studied community. Data collected over a period of 15 years (1994 to 2009) in Masiphumelele, a township near Cape Town, South Africa are used to develop a community-level mathematical model of the local HIV-TB epidemic. The population is divided into six compartments and a system of di®erential equations is derived to describe the spread of the dual
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15

García, García Juan Ignacio. "STIs/HIV and HIV/TB interventions for prevention and control of syndemics in resource-constrained settings." Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/670174.

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Aquesta tesi doctoral versa sobre epidèmies simultànies i la interacció biològica i epidemiològica en espai, població i temps en països de escassos recursos. Aquesta tesi aborda la implementació de diferents models assistencials per cobrir les necessitats de les poblacions afectades. La tesi s’ organitza com a compendi de 6 publicacions (4 articles publicats i 2 en procés de publicació) sobre infeccions de transmissió sexual (ITS), VIH i tuberculosi (TB). Hi ha dues parts diferenciades, la part de ITS/VIH i la part de VIH/TB amb l’ VIH com a nexe d’ unió. Les dues publicacions de la part de IT
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16

Lucca, Maria Elvira Santos de. "Análise epidemiológica da tuberculose e co-infecção HIV/TB, em Ribeirão Preto-SP, de 1998-2006." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/17/17139/tde-01042008-151419/.

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A pesquisa teve como objetivo analisar o Programa de Controle da Tuberculose (PCT) no município de Ribeirão Preto -São Paulo, no período de 1998 a 2006. Utilizou-se para este propósito indicadores epidemiológicos e de desempenho construídos a partir de dados das fichas de notificação de tuberculose (TB) armazenadas no sistema de informação o EPI-Tb, da Secretaria municipal de saúde deste município e os dados populacionais de estimativas do DATASUS, do período de estudo. Selecionaram-se para o estudo casos novos de TB notificados e residentes no município, por ano de diagnóstico, excluindo-se c
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17

Trinh, Quynh Mai. "Epidemiology and genomics of Mycobacterium tuberculosis in TB/HIV co-infection in Vietnam." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20231.

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TB and human HIV infection have mutually detrimental effects that complicate patient management and global TB control efforts. The overall aim was to improve our understanding of the TB epidemiology, drug resistance profile, and transmission dynamics among people living with HIV in Vietnam. The global epidemiology of TB, HIV and TB/HIV co-infection in low and high incidence countries with a specific focus on the Asia-Pacific region and relevant disease trends within Vietnam was described. Findings from a retrospective study with 200 M. tuberculosis isolates from TB/HIV co-infected patients in
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18

Ncube, Wenzokuhle S. "People’s understanding of TB in a setting of high HIV/TB prevalence: case studies in Gugulethu Township, Western Cape Province." University of the Western Cape, 2014. http://hdl.handle.net/11394/4170.

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Magister Artium (Development Studies) - MA(DVS)<br>Tuberculosis (TB) infection is present in many people but it is sometimes latent until one’s immune system is compromised. As such, it increasingly manifests in people, especially those whose immune system has been compromised by e.g. HIV, as an opportunistic disease. TB is thus closely interlinked with HIV and efforts to eradicate TB have been integrated with the fight against HIV in South Africa. The study revealed that factors such as poverty and stigma - be it enacted or perceived - has an impact on how people with TB deal with the burden
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19

Ayles, Helen Mary. "Approaches to the dual threat of HIV and TB in Lusaka, Zambia." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409678.

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20

Cavalin, Roberta Figueiredo. "Coinfecção TB-HIV: análise espacial e temporal no município de São Paulo." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/6/6143/tde-11062018-095251/.

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Introdução - A tuberculose (TB) e a Síndrome da Imunodeficiência Adquirida (AIDS) são os agravos de origem infecciosa com maior mortalidade no mundo. O vírus da imunodeficiência humana (HIV) compromete o sistema imunológico e favorece o adoecimento por TB e, nesta perspectiva, a coinfecção TB-HIV constitui uma associação potencialmente fatal. Objetivos - Descrever os casos novos de TB coinfectados pelo HIV e analisar os padrões de distribuição espacial e temporal da coinfecção no município de São Paulo. Método - Estudo descritivo, analítico e de série temporal com dados do Sistema de Notificaç
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21

Cortez, Escalante Juan José. "Modelo prognóstico de desenvolvimento de TB ativa nos pacientes com HIV/Aids." reponame:Repositório Institucional da UnB, 2008. http://repositorio.unb.br/handle/10482/1301.

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Tese (doutorado)—Universidade de Brasília, Faculdade de Medicina, 2008.<br>Submitted by Jaqueline Oliveira (jaqueoliveiram@gmail.com) on 2008-12-11T18:15:49Z No. of bitstreams: 1 TESE_2008_JuanJCEscalante.pdf: 4789546 bytes, checksum: 592c90d5f7b6e9da19c34782bde221bf (MD5)<br>Approved for entry into archive by Georgia Fernandes(georgia@bce.unb.br) on 2009-02-19T15:32:57Z (GMT) No. of bitstreams: 1 TESE_2008_JuanJCEscalante.pdf: 4789546 bytes, checksum: 592c90d5f7b6e9da19c34782bde221bf (MD5)<br>Made available in DSpace on 2009-02-19T15:32:57Z (GMT). No. of bitstreams: 1 TESE_2008_JuanJCEsca
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Makatsa, Mohau Steven. "Characterization of Mycobacterium tuberculosis-specific Th22 cells in HIV-TB co-infection." Doctoral thesis, Faculty of Health Sciences, 2020. http://hdl.handle.net/11427/32398.

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Tuberculosis (TB) remains the infectious disease causing the greatest global mortality, with an estimated 10 million incident cases of TB and 1.45 million deaths in 2018. Although there is a cure for TB, the success of the treatment is hampered by multidrug resistant TB and HIV infection. There is an urgent need for an effective TB vaccine to prevent ongoing transmission. The development of a new and efficacious TB vaccine will likely be dependent on our understanding of protective immunity to TB. Although it is well established that Th1 cells are crucial in the response against Mycobacterium
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23

Orikiriza, Patrick. "Improving diagnosis of childhood tuberculosis in a high TB-HIV prevalent setting." Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTT026.

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L’Organisation Mondiale de la Santé estime qu’en 2017 près d’un million d’enfants de moins de 15 ans ont développé la tuberculose mais seulement la moitié des cas ont été notifiés. Les difficultés pour recueillir des échantillons de crachat chez les enfants et la nature paucibacillifère de la tuberculose pédiatrique représentent de véritables challenges diagnostiques. Cela aboutit à la prescription fréquente de traitement empirique avec un risque de sur- ou sous-diagnostic. De plus, peu de laboratoires dans les pays à ressources limitées ont les capacités du diagnostic de la tuberculose. Les é
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Lourens, Guinevere Margaretha Attilla. "TB and HIV community-outreach training project in a higher education institution." Thesis, [S.l. : s.n.], 2009. http://dk.cput.ac.za/cgi/viewcontent.cgi?article=1021&context=td_cput.

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Frigati, Lisa Jane. "The impact of isoniazid preventative therapy and antiretroviral therapy on tuberculosis (TB) in HIV-infected children in a high TB incidence setting." Master's thesis, University of Cape Town, 2011. http://hdl.handle.net/11427/10467.

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The aim of this study is to investigate the combined effect of IPT [INH preventative therapy] and ART [antiretroviral therapy] on TB incidence in HIV-infected children. A cohort analysis will be performed using data from a prospective, double-blinded placebo controlled trial of INH versus placebo in HIV-infected children in Cape Town, South Africa.
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Phetlhu, Deliwe René. "Stigmatisation of a patient co-infected with TB and HIV / Deliwe René Phetlhu." Thesis, North-West University, 2005. http://hdl.handle.net/10394/876.

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The last few years have seen an increase in the infection rate not only of HIV but also TB. The HIV/AIDS pandemic is increasing rapidly mainly in developing countries with 71 % of infections in the Sub-Saharan region of Africa. South Africa, which forms part of the Sub- Saharan region, has the highest infection rate in the world with 3.2 to 3.4 million people living with HIV/AIDS. People with HIV are especially vulnerable to TB, and HIV pandemic is fuelling an explosive growth in TB cases. The increase in the infection rate of TB and HIV exert increased pressure on health service delivery thus
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Souza, Christiane Moreira. "Sobrevida de portadores da coinfecção HIV/TB em Goiás: um estudo de coorte." Universidade Federal de Goiás, 2014. http://repositorio.bc.ufg.br/tede/handle/tede/4252.

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Submitted by Cássia Santos (cassia.bcufg@gmail.com) on 2015-03-05T12:33:52Z No. of bitstreams: 2 Dissertação - Christiane Moreira Souza - 2014.pdf: 1441222 bytes, checksum: cad3b73e713dcfed6bbf1d0600f3311e (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2015-03-06T10:39:32Z (GMT) No. of bitstreams: 2 Dissertação - Christiane Moreira Souza - 2014.pdf: 1441222 bytes, checksum: cad3b73e713dcfed6bbf1d0600f3311e (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (M
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Mbunyuza, Lungelwa. "Treatment adherence in TB/HIV co-infected patients in Mount Frere, Eastern Cape." University of Western Cape, 2020. http://hdl.handle.net/11394/8051.

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Master of Public Health - MPH<br>Adequate levels of adherence to treatment for tuberculosis (TB) and HIV at the same time poses a problem for public health in South Africa. TB/HIV co-infected patients face many potential barriers to adherence to treatment for both conditions. There is a need for more knowledge about factors influencing treatment adherence in co-infected patients on concomitant treatment. The aim of this study was to explore the barriers and facilitators to treatment adherence among people co-infected with TB/HIV living in the Alfred Nzo District, Eastern Cape, in order to iden
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Thawer, Narjis Khatoon G. "Investigating defects in monocyte responses to Mycobacterium tuberculosis in HIV-TB co-infection." Master's thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/5923.

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Decloedt, Eric Hermann. "Treatment of HIV associated neurocognitive disorders." Doctoral thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29616.

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Background Human immunodeficiency virus (HIV) invades the central nervous system (CNS) as early as 8 days after HIV infection, causing a wide spectrum of neuropathological changes including HIV associated neurocognitive disorders (HAND). HAND is a spectrum of cognitive impairment, which in its most severe form cause marked interference with day-to-day functioning (HIV-associated dementia). Antiretroviral therapy (ART) has substantially reduced the incidence of HIV-associated dementia, but has not had an impact on the overall prevalence of HAND. The prevalence of milder stages of HAND in ART
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Nhamoyebonde, Shepherd. "Vitamin D and HIV associated tuberculosis." Thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/3443.

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Marais, Suzaan. "Investigations into HIV-associated tuberculous meningitis." Doctoral thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/9304.

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Includes bibliographical references.<br>[Background] Tuberculous meningitis (TBM) is a common form of tuberculosis in high TB incidence settings. However, the burden of disease and outcome in affected adults is unknown in Cape Town. The diagnosis of TBM is often challenging, particularly in HIV co-infected patients and no standardized clinical case definition exists. An emerging complication that contributes to poor outcome in HIV-associated TBM is neurological TB immune reconstitution inflammatory syndrome (TB-IRIS). [Methods] A consensus clinical TBM case definition was developed following a
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Newton, Robert. "The epidemiology of HIV-associated cancers." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284600.

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Inchley-Mort, Sophie. "Induction and HIV-associated neurocognitive disorders." Thesis, University of East London, 2015. http://roar.uel.ac.uk/4471/.

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Antiretroviral medication has improved HIV-related prognosis. Yet HIV-associated neurocognitive disorders (HAND) have substantially increased, leading to decreased quality of life, increased illness severity and mortality. In the research literature, executive dysfunction (e.g. planning difficulties and cognitive inflexibility) has been identified as prominent in HAND, but there has been little analysis of the componential and qualitative aspects underpinning these deficits. Targeted and theory-driven neurorehabilition for HAND is limited due to the lack of this type of detailed information. T
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Kakili, Tuwilika. "Factors that contribute to treatment defaulting amongst tuberculosis patients in Windhoek district, Namibia." Thesis, University of the Western Cape, 2010. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_2049_1363356699.

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<p>Background: Tuberculosis (TB) is a resurgent disease in many parts of the world, fuelled by HIV/AIDS and poverty. According to WHO, over two billion people were estimated to be infected by TB globally, 9.4 million new cases of TB were reported, while about 1.7 million people were estimated to have lost their lives to TB in 2009 (WHO, 2010). The&nbsp<br>global defaulter rate for TB was estimated at about 9% in 2007 (WHO, 2007). With Africa remaining the global epicentre of the TB epidemic, the epidemic in Sub-Saharan Africa,&nbsp<br>one of the worst affected areas in the world, shows no evid
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Shenje, Justin Tapiwa. "Tuberculous pericarditis in HIV co-infected compared to those without HIV co-infection." Diss., University of Pretoria, 2013. http://hdl.handle.net/2263/33504.

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Introduction: Tuberculosis (TB) pericarditis is a relatively rare form of tuberculosis which has been on the decline. However, the advent of the human immunodeficiency virus (HIV) pandemic has brought about the resurgence of tuberculosis pericarditis and an even poorer prognosis for patients with HIV co-infection. Objectives: The aim is to describe the baseline characteristics of tuberculous pericarditis patients and to assess the impact of HIV on the clinical presentation of this disease. Methods: The study describes baseline data from a randomised clinical trial which explored the use o
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Chimatira, Raymond. "Challenges, barriers and opportunities in integrating TB/HIV services in Tsandi District Hospital, Namibia." Thesis, University of Western Cape, 2012. http://hdl.handle.net/11394/3308.

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Magister Public Health - MPH<br>BACKGROUND: Namibia has generalised Human Immunodeficiency Virus (HIV) and tuberculosis (TB) epidemics. In response to the TB/HIV co-epidemics in Namibia, the Ministry of Health and Social Services approved a policy of TB/HIV collaborative activities at national level and the integration of TB/HIV services at the point of service delivery. The present study explored barriers and facilitators of integration of TB and HIV service delivery in Tsandi District Hospital, which lies in rural northern Namibia. It focused on understanding the perspectives of healthcare w
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Ferrand, Rashida Abbas. "Burden of HIV infection and HIV-associated morbidity in Zimbabwean adolescents." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2010. http://researchonline.lshtm.ac.uk/682408/.

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This thesis concerns the clinical epidemiology of HIV infection in Zimbabwean adolescents. Without treatment, there is a very high risk of death in the early years of life in HIV-infected infants. However, in recent years increasing numbers of adolescents have been presenting to health care services with symptomatic HIV infection and with features suggesting longstanding disease. Population-based surveys in Southern Africa have shown HIV prevalence rates among older children and adolescents to be much higher than would be anticipated if HIV-infants were not surviving early childhood. The burde
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Chung, Delgado Kocfa, Bravo Sonia Guillen, Montag Alejandro Revilla, and Antonio Bernabe-Ortiz. "Mortality Among MDR-TB Cases: Comparison with Drug-Susceptible Tuberculosis and Associated Factors." PLoS ONE, 2015. http://hdl.handle.net/10757/344468.

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kocfachung@gmail.com<br>soniaguillenb@gmail.com<br>armrons@gmail.com<br>Artículo de revista que fue aceptada para publicación en la Revista PLOS ONE el 03 de Febrero de 2015.<br>Background: An increase in multidrug-resistant tuberculosis (MDR-TB) cases is evident worldwide. Its management implies a complex treatment, high costs, more toxic anti-tuberculosis drug use, longer treatment time and increased treatment failure and mortality. The aims of this study were to compare mortality between MDR and drug-susceptible cases of tuberculosis, and to determine risk factors associated with mortality
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Shigayeva, Altynay. "TB and HIV/AIDS control programmes in central Asia : health systems' challenges to sustainability." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2011. http://researchonline.lshtm.ac.uk/901046/.

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Health systems in central Asia (the former Soviet Union) face challenges to control TB and HIV/AIDS epidemics. Integration of communicable disease control programmes with the broader health system has been recommended to ensure programmes' sustainability. An important constraint for studying sustainability and integration has been a lack of conceptual clarity. Drawing on a critical assessmenot f publishedl iterature, a novel conceptualf ramework for the analysis of sustainability and integration in health systems has been developed. A sustainablec ommunicabled iseasep rogrammei s defined as co
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Sinanovic, Edina. "Tuberculosis treatment in high TB/HIV settings : evaluating public-private partnerships in South Africa." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2004. http://researchonline.lshtm.ac.uk/682333/.

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The aim of this thesis is to evaluate the perfonnance of different models of publicprivate partnerships in the provision of tuberculosis treatment, and explore incentive mechanisms for private sector participation. It makes recommendations to policymakers in South Africa and elsewhere on the best way to approach a policy on the enhanced role of private sector providers in tuberculosis treatment in light of the HIV/AIDS epidemic. A common framework is used to analyse the nature of the models, their perfonnance in tenns of cost, effectiveness and quality of care, and incentives for private parti
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Ndoro, Tinashe T. R. "Attitudes and perceptions towards TB in Grahamstown East in a time of HIV/AIDS." Thesis, Rhodes University, 2009. http://hdl.handle.net/10962/d1002539.

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Tuberculosis (TB) has become a serious South African health problem because it is the most common opportunistic disease that leads to death in people with HIV/AIDS. Due to the airborne nature of the disease it can easily be spread to anyone including healthy people. A lack of compliance to treatment by TB patients explains why prevalence rates of the disease are high and why there is an emergence of drug resistant strains such as XDR-TB and MDR-TB. Information on existing knowledge, attitudes and perceptions regarding TB can provide a crucial foundation for the development of educational progr
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LORIATO, K. C. "ANÁLISE ESPACIAL DE COINFECÇÃO TB/HIV EM MICRORREGIÕES DO BRASIL DE 2007 A 2011." Universidade Federal do Espírito Santo, 2017. http://repositorio.ufes.br/handle/10/7154.

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Made available in DSpace on 2018-08-01T21:35:35Z (GMT). No. of bitstreams: 1 tese_11582_Dissertação_Karina Covre Loriato.pdf: 1924451 bytes, checksum: 4638dc89f01fa114ce9598e6a04d806f (MD5) Previous issue date: 2017-05-16<br>Introdução: A infecção pelo vírus da imunodeficiência humana (HIV) é um importante fator de risco para o adoecimento por tuberculose (TB). O conhecimento da distribuição e da dependência espacial dos casos de tuberculose e HIV/AIDS no Brasil possibilitará a visualização de sua distribuição geográfica e a frequência de ocorrência da coinfecção no espaço/tempo. Objetivos:
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Guedes, Gabriela de Moraes Rêgo. "Avaliação dos testes QuantiFERON-TB GOLD e Nested PCR em único tubo no diagnóstico de tuberculose em pacientes imunodeprimidos." Universidade Federal de Pernambuco, 2013. https://repositorio.ufpe.br/handle/123456789/13214.

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Submitted by Daniella Sodre (daniella.sodre@ufpe.br) on 2015-04-15T15:11:48Z No. of bitstreams: 2 TESE Gabriela Guedes.pdf: 1658990 bytes, checksum: d74ac5823949c1e44d7efd506322f238 (MD5) license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5)<br>Made available in DSpace on 2015-04-15T15:11:48Z (GMT). No. of bitstreams: 2 TESE Gabriela Guedes.pdf: 1658990 bytes, checksum: d74ac5823949c1e44d7efd506322f238 (MD5) license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Previous issue date: 2013<br>A imunossupressão, causada por diversos fatores tais como desnu
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de, Jager Veronique Rejean. "Trends in the presenting clinical profile of patients with pulmonary tuberculosis in the Western Cape, 1991 - 2009." University of the Western Cape, 2017. http://hdl.handle.net/11394/6455.

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Magister Public Health - MPH (Public Health)<br>Over the past two decades, despite a growing tuberculosis (TB) epidemic, the South African health system and National TB Programme (NTP) have taken significant steps to ensure improved clinical awareness, early diagnosis, prompt treatment initiation and follow-up of treatment outcomes in cases of TB. The effects of these programmatic measures over time on changes in the severity of disease and presenting clinical profile of patients with pulmonary TB have not been studied. Doing so may provide another window on the impact of TB control initiative
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Pean, Polidy. "Le rôle de l’immunité à médiation cellulaire dans le syndrome inflammatoire de reconstitution immunitaire chez les patients co-infectés VIH/TB sous traitement antituberculeux et antirétroviraux au Cambodge." Thesis, Montpellier 1, 2011. http://www.theses.fr/2011MON13514/document.

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Syndrome inflammatoire lié à la reconstitution immunitaire chez le patient coinfecté par le VIH et la tuberculose est une complication du traitement par des antirétroviraux, appelé TB-IRIS. Ce syndrome est souvent rencontré dans les pays en voie de développement. Son diagnostic se pose essentiellement sur la présentation clinique et nécessiter de se différentier des autres pathologies. Son évolution est souvent favorable ou sous corticoïde mais certaine forme est sévère et/ou mortelle. L'étude de leur mécanisme permettra d'identifier de marqueur prédictif, applicable à leur diagnostic précoce
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Pandey, Vinita. "Cellular mechanisms underlying HIV 1 associated dementia." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251817.

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Peng, Yanchun. "HLA-B51 associated HIV-1 viral control." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:8e06bed0-bd8d-4774-b137-c12f5e3547fc.

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Polymorphism in the Human Leucocyte Antigen (HLA) region of chromosome is the major source of host genetic variability in outcome of HIV-1 infection. However, there is limited understanding of the mechanisms underlying the beneficial effect of protective class I alleles such as HLA-B57, B27 and B51. Taking advantage of a unique cohort (SM cohort) infected with clade B’ HIV-1 through contaminated blood, in which many variables, such as the length of infection, the infecting viral strain and host genetic background are controlled, we performed a comprehensive study in order to understand HLA-B51
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Nowotny, Ewa. "Social cognition and HIV-associated neurocognitive disorders." Thesis, University of East London, 2016. http://roar.uel.ac.uk/5399/.

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Introduction: The introduction of antiretroviral therapy has successfully transformed the Human Immunodeficiency Virus (HIV) into a long-term condition. However, nearly half of those living with HIV experience cognitive difficulties (HIV-associated Neurocognitive Disorders; HAND). The adverse effects of HIV on cognitive function have been well-documented. However, it has not been established whether individuals with HAND present with deficits in social cognition, specifically related to the ability to understand other people’s intentions and feelings (Theory of Mind; ToM). The present study ai
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Atwine, Daniel. "Improving TB management and control through innovative shorter anti-tuberculosis regimens." Thesis, Montpellier, 2017. http://www.theses.fr/2017MONTT041/document.

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Le traitement actuel de la tuberculose chimio-sensible est de 6 mois, ce qui est beaucoup trop long et entraine des défauts d’adhésion au traitement, des échecs thérapeutiques par sélection de bactéries résistantes. Puisque dans le futur proche, aucun nouveau traitement ne permettra de raccourcir la durée de traitement, d’autres voies doivent être recherchées, entre autres l’augmentation de la posologie de rifampicine (R) au-delà des 10 mg/kg actuellement recommandés qui pourrait permettre un traitement de 3-4 mois.Notre travail, réalisé dans le cadre d’essais cliniques, a consisté d’une part
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