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Littérature scientifique sur le sujet « Ig M antibody »

Auteur : Grafiati

Publié le 2 juin 2025

Mis à jour le 31 juillet 2025

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Articles de revues sur le sujet "Ig M antibody"

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Fadeyi, Emmanuel A., Tawfeq Naal, Mary Green, Julie H. Simmons, Mary Rose Jones, and Gregory J. Pomper. "Anti-M–Induced Delayed Hemolytic Transfusion Reaction." Laboratory Medicine 51, no. 4 (2019): 426–29. http://dx.doi.org/10.1093/labmed/lmz078.

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Abstract Background Anti-M is most often assumed to be naturally occurring and can be comprised of a mixture of predominantly immunoglobulin(Ig)M with a lesser IgG component. Anti-M-antibodies usually do not react at 37°C and therefore are considered to be of little clinical significance. Methods A 28-year-old man presented with hemorrhagic shock from numerous injuries sustained in a motor vehicle collision. The patient received several units of red blood cells (RBCs). The antibody screen, the direct antiglobulin test (DAT), and the RBC genotype were sent for laboratory evaluation. Results A t

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Elliott, T. J., M. J. Glennie, H. M. McBride, and G. T. Stevenson. "Analysis of the interaction of antibodies with immunoglobulin idiotypes on neoplastic B lymphocytes: implications for immunotherapy." Journal of Immunology 138, no. 3 (1987): 981–88. http://dx.doi.org/10.4049/jimmunol.138.3.981.

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Abstract We have examined the reactions of a panel of nine monoclonal anti-idiotype antibodies with the surface immunoglobulin in situ on guinea pig L2C leukemic lymphocytes. Equilibrium binding constants were shown to range between 10(7) and 10(8) M-1 for univalent Fab' gamma fragments and between 10(8) and 10(9) M-1 for intact IgG. Saturation of the cell surface binding sites was achieved with 2.9 X 10(5) Fab' gamma molecules/cell and 1.2 X 10(5) IgG molecules/cell for each antibody, a result that is consistent with a bivalent mode of interaction for the IgG. Despite these overall similariti

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Hinton, Dennis M., and Mushtaq A. Khan. "Evaluation of the Miniature Swine for Use in Immunotoxicity Assessment: I. Quantitation of Humoral Responses to Sheep Red Blood Cells and Effects of Cyclophosphamide." Journal of the American College of Toxicology 8, no. 5 (1989): 1039–52. http://dx.doi.org/10.3109/10915818909018064.

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T-cell-dependent and t-independent humoral responses as well as cell-mediated re-sponses(1) were assessed with groups of young, Hormel-Hanford miniature swine. Test antigens established in various immunotoxicity studies with rodents were used. Results with the widely used t-dependent test antigen, sheep red blood cells (SRBC), are presented in this report. Groups of swine were immunized with varying dosages of SRBC to evaluate basal responses. Serum antibody titers were estimated by the standardized hemolysin (HLY) visual endpoint (EP) assay and a quantitative spectro-photometric (SP) variatio

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Guy, James S., and Leon N. D. Potgieter. "Kinetics of antibody formation after the reactivation of bovine herpesvirus-1 infection in cattle." American Journal of Veterinary Research 46, no. 4 (1985): 899–901. https://doi.org/10.2460/ajvr.1985.46.04.899.

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SUMMARY Holstein heifers previously infected with bovine herpesvirus-1 were treated with corticosteroids to reactivate latent infection. The kinetics of serum immunoglobulin (Ig) M, IgG1, and IgG2 antibody formation were determined. The secondary immune response which developed as a consequence of virus reactivation was characterized by an anamnestic IgG antibody response. Secondary IgGl and IgG2 antibody formation constituted the IgG antibody response. In addition, secondary IgM antibody formation was elicited by this form of bovine herpesvirus-1 antigenic exposure.

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Gong, Xiaoting, Huige Yan, Junfan Ma, et al. "Macrophage-Derived Immunoglobulin M Inhibits Inflammatory Responses via Modulating Endoplasmic Reticulum Stress." Cells 10, no. 11 (2021): 2812. http://dx.doi.org/10.3390/cells10112812.

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Immunoglobulin (Ig), a characteristic marker of B cells, is a multifunctional evolutionary conserved antibody critical for maintaining tissue homeostasis and developing fully protective humoral responses to pathogens. Increasing evidence revealed that Ig is widely expressed in non-immune cells; moreover, Ig produced by different lineages cells plays different biological roles. Recently, it has been reported that monocytes or macrophages also express Ig. However, its function remains unclear. In this study, we further identified that Ig, especially Ig mu heavy chain (IgM), was mainly expressed

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Seriwatana, Jitvimol, Mrigendra P. Shrestha, Robert M. Scott, et al. "Clinical and Epidemiological Relevance of Quantitating Hepatitis E Virus-Specific Immunoglobulin M." Clinical and Vaccine Immunology 9, no. 5 (2002): 1072–78. http://dx.doi.org/10.1128/cdli.9.5.1072-1078.2002.

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ABSTRACT Diagnosis of acute hepatitis E by detection of hepatitis E virus (HEV)-specific immunoglobulin M (IgM) is an established procedure. We investigated whether quantitation of HEV IgM and its ratio to HEV total Ig furnished more information than conventional IgM tests that are interpreted as positive or negative. A previously described indirect immunoassay for total Ig against a baculovirus-expressed HEV capsid protein was modified to quantitate HEV-specific IgM in Walter Reed (WR) antibody units by using a reference antiserum and the four-parameter logistic model. A receiver-operating ch

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Kim, Dong-Min, Choon-Mee Kim, and Na Ra Yun. "2138. Follow-up Investigation of Antibody Titers and Diagnostic Antibody Cut-Off Values in Scrub Typhus Patients in Korea." Open Forum Infectious Diseases 6, Supplement_2 (2019): S724—S725. http://dx.doi.org/10.1093/ofid/ofz360.1818.

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Abstract Background Scrub typhus is a mite-borne infectious disease caused by Orientia tsutsugamushi. There have been few follow-up studies assessing antibody titers using serologic tests from various commercial labs. Methods A prospective investigation to assess antibody titers of scrub typhus patients and seroprevalence for health checkup individuals were evaluated. The antibody titers of former patients diagnosed with scrub typhus at least 1 year and a maximum of 13 years were also investigated. The following tests were performed simultaneously: (i) immunofluorescence antibody assays (IFAs)

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Chan, Owen T. M., Lynn G. Hannum, Ann M. Haberman, Michael P. Madaio, and Mark J. Shlomchik. "A Novel Mouse with B Cells but Lacking Serum Antibody Reveals an Antibody-independent Role for B Cells in Murine Lupus." Journal of Experimental Medicine 189, no. 10 (1999): 1639–48. http://dx.doi.org/10.1084/jem.189.10.1639.

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The precise role of B cells in systemic autoimmunity is incompletely understood. Although B cells are necessary for expression of disease (Chan, O., and M.J. Shlomchik. 1998. J. Immunol. 160:51–59, and Shlomchik, M.J., M.P. Madaio, D. Ni, M. Trounstine, and D. Huszar. 1994. J. Exp. Med. 180:1295–1306), it is unclear whether autoantibody production, antigen presentation, and/or other B cell functions are required for the complete pathologic phenotype. To address this issue, two experimental approaches were used. In the first, the individual contributions of circulating antibodies and B cells we

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Jaskowski, T. D., T. B. Martins, C. M. Litwin, and H. R. Hill. "Immunoglobulin (Ig) M antibody against myelin associated glycoprotein (MAG): A comparison of methods." Journal of Clinical Laboratory Analysis 18, no. 4 (2004): 247–50. http://dx.doi.org/10.1002/jcla.20031.

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Pelletier, R. P., R. G. Ohye, A. Vanbuskirk, et al. "Importance of endothelial VCAM-1 for inflammatory leukocytic infiltration in vivo." Journal of Immunology 149, no. 7 (1992): 2473–81. http://dx.doi.org/10.4049/jimmunol.149.7.2473.

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Abstract The microvascular endothelia of rejecting DBA/2----C57B1/6 murine cardiac allografts develop reactivity with the mAb M/K-2, which recognizes the murine homologue of the human leukocyte adhesion molecule VCAM-1. This reactivity does not develop in DBA/2----DBA/2 cardiac isografts or normal DBA/2 cardiac tissues. To determine whether endothelial VCAM-1 plays a role in allograft inflammation, cardiac allograft recipients were treated with M/K-2 antibody and monitored for leukocytic graft infiltration and graft survival. Treatment of the graft recipients with 200 micrograms/day M/K-2 Ig p

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Actes de conférences sur le sujet "Ig M antibody"

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Matsuda, T. "Early Detection of Bordetella Pertussis and Bordetella Parapertussis Infection with Pertussis Antibody Ig-M, Ig-A, and IgM/IgA Ratio." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6161.

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