Bibliographies thématiques / Implantable Drug Delivery System (IDDS)

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Littérature scientifique sur le sujet « Implantable Drug Delivery System (IDDS) »

Auteur : Grafiati

Publié le 7 juin 2025

Mis à jour le 2 août 2025

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Articles de revues sur le sujet "Implantable Drug Delivery System (IDDS)"

Yogita, Pawar* Shubhangi doer Priti Kolte Nitin kale. "Implantable Drug Delivery System." International Journal of Pharmaceutical Sciences 2, no. 8 (2024): 3684–88. https://doi.org/10.5281/zenodo.13369182.

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Implantable drug delivery system [IDDs] in modern medicine may traced to Deans by and Parkes who in 1938. The oral route is popular and convenient means of drug delivery . with there advantage there is also challenges. many drug are not suitable for the oral route of administration such as insulin. this article gives an overview of classification of these drug delivery devices ;the mechanism of drug release ;the materials used for manufacture. Implants are small sterile solid masses consisting of highly purified drug made by compression or molding or extrusion. Implants are developed with a vi

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Swetha, Dr M., Makka Vandana, Mandugula Shiva Nandini, and Manumari Vaishnavi. "Implantable Drug Delivery System." International Journal of Multidisciplinary Research and Growth Evaluation 6, no. 1 (2025): 1578–82. https://doi.org/10.54660/.ijmrge.2025.6.1.1578-1582.

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Implantable drug delivery systems [IDDS] provide a viable substitute for conventional medication delivery techniques. The most popular medication delivery methods, oral and injectable, frequently cause blood drug concentrations to peak and then fall. This calls for ongoing administration in order to sustain therapeutic medication levels. Oral medication distribution also has to contend with issues such first-pass metabolism and drug degradation in the gastrointestinal system. Conversely, IDDS allow for prolonged medication release, which makes them particularly useful for treating chronic illn

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Vaishnavi S. Mukhmale, Sakshi Y. Patrikar, Nandkishor B. Deshmukh, and Swati P. Deshmukh. "Implantable drug delivery systems: An overviews." GSC Advanced Research and Reviews 22, no. 1 (2025): 123–32. https://doi.org/10.30574/gscarr.2025.22.1.0002.

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Implant are sterile solid mass that contains medicine, prepared by different ways like extrusion, moulding or contraction. The conventional routes of medicine administration has limited control over medicine release and maintaining constant tube remedial medicine attention for longer ages of time. To avoid these problems associated with application of traditional lozenge forms, there was essential need for development of new lozenge forms which would discharge medicines at controlled rate for original exertion. This led to enhancement of Novel Drug Delivery Systems (NDDS) that offers optimisat

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Haider, Rehan. "Implanted Drug Delivery System for Control of Chronic Pain." New Medical Innovations and Research 6, no. 3 (2025): 01–10. https://doi.org/10.31579/2767-7370/147.

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Implanted drug delivery system {IDDS} have emerged as a promising strategy for managing chronic pain, offering precise and sustained drug administration to achieve optimal pain relief while minimizing adverse effects. This abstract reviews the key aspects of IDDS in the context of chronic pain control. Chronic pain, characterized by its persistence over extended periods, presents a significant challenge in medical practice due to its complex and multifaceted nature. Traditional oral medication often fall short of providing consistent pain relief while avoiding systemic side effects. IDDS addre

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Stearns, L. J., W. H. Poling, J. Kiser, J. Nasternak, and E. Berryman. "Pancreatic cancer survivorship: Intrathecal drug delivery system for pain management." Journal of Clinical Oncology 24, no. 18_suppl (2006): 14100. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.14100.

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14100 Background: Pancreatic cancer is predominantly unresectable at diagnosis and is most frequently fatal. Nationally the average survivorship is 10 months. Among pancreatic cancer patients, pain is associated with decreased survival rates. Quality of life and survivorship are the principal outcome measures for these patients. Successful pain management may be a significant predictor of prolonged survivorship. No study has demonstrated an impact on survivorship secondary to the treatment of pancreatic cancer pain and the use of Intrathecal Drug Delivery Systems (IDDS). Methods: A retrospecti

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Amreen, Soha, S. M. Shahidulla, Aasia Sultana, and Nimrah Fatima. "Implantable Drug Delivery System: An Innovative Approach." Journal of Drug Delivery and Therapeutics 13, no. 5 (2023): 98–105. http://dx.doi.org/10.22270/jddt.v13i5.6069.

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The conventional routes of drug administration has limited control over drug release and maintaining constant plasma therapeutic drug concentrations for longer periods of time. To avoid these problems associated with utilization of traditional dosage forms, there was essential need for development of new dosage forms which would discharge drugs at controlled rate for local activity. This led to improvement of Novel Drug Delivery Systems (NDDS) that offers optimisation of therapeutic properties of drugs and makes them safer, productive and dependable over traditional ways of administration. Imp

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Smith, Thomas J., Peter S. Staats, Timothy Deer, et al. "Randomized Clinical Trial of an Implantable Drug Delivery System Compared With Comprehensive Medical Management for Refractory Cancer Pain: Impact on Pain, Drug-Related Toxicity, and Survival." Journal of Clinical Oncology 20, no. 19 (2002): 4040–49. http://dx.doi.org/10.1200/jco.2002.02.118.

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PURPOSE: Implantable intrathecal drug delivery systems (IDDSs) have been used to manage refractory cancer pain, but there are no randomized clinical trial (RCT) data comparing them with comprehensive medical management (CMM). PATIENTS AND METHODS: We enrolled 202 patients on an RCT of CMM versus IDDS plus CMM. Entry criteria included unrelieved pain (visual analog scale [VAS] pain scores ≥ 5 on a 0 to 10 scale). Clinical success was defined as ≥ 20% reduction in VAS scores, or equal scores with ≥ 20% reduction in toxicity. The main outcome measure was pain control combined with change of toxic

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Tanisha, Bhagria *Anjali, and Duggal Sanjiv. "IMPLANTATIONS: REVOLUTIONIZING DRUG DELIVERY FOR IMPROVED PATIENT OUTCOMES." World Journal of Pharmaceutical Science and Research 4, no. 2 (2025): 1027–41. https://doi.org/10.5281/zenodo.15356074.

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The oral route of administration is the most popular and convenient route of drug delivery. However, despite its advantages, it also has limitations. There are many drugs that are not suitable for oral route of administration due to their first pass metabolism, ideal characteristics and adverse effects of the treatment. Moreover, the effectiveness of oral delivery depends significantly on patient adherence. Implantable drug delivery devices (IDDS) are an alternative system that can achieve effective delivery of drug with appropriate concentrations. As a result, it reduces the systemic side-eff

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Goel, Vasudha, Melissa Ann Geller, Anne Hudson Blaes, and Amitabh Gulati. "Intrathecal drug delivery systems for cancer pain control: Insights on current contemporary practices in the US." Journal of Clinical Oncology 41, no. 16_suppl (2023): 6605. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.6605.

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6605 Background: About a third of cancer survivors report moderate to severe pain. Intrathecal drug delivery system (IDDS) is an implantable pain control option for treating intractable chronic pain not responsive to systemic opioid therapy. Studies on the current practices in the US around the utilization of IDDS for cancer pain are lacking. Methods: The Nationwide inpatient sample (NIS) dataset is funded by the Agency for healthcare research and quality (AHRQ) for multistate healthcare research & decision-making. Adult patients admitted to hospitals with a primary or secondary cancer dia

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Han, Xiao-Le, Tao Zhou, Jian-Ming Xu, Shu-Feng Zhang, Ye-Zhou Hu, and Yi Liu. "Integrated Perspective on Functional Organic Electrochemical Transistors and Biosensors in Implantable Drug Delivery Systems." Chemosensors 13, no. 6 (2025): 215. https://doi.org/10.3390/chemosensors13060215.

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Although traditional drug delivery methods are widely used in clinical practice, their inherent limitations often compromise therapeutic efficacy. Therefore, the development of more precise and efficient drug delivery systems is essential to enhance treatment outcomes and reduce adverse effects. Implantable drug delivery systems (IDDSs) represent intelligent platforms capable of autonomously regulating drug release in response to a patient’s physiological state. By enabling controlled release and personalized dosing, IDDSs have been widely applied in the management of chronic conditions such a

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Thèses sur le sujet "Implantable Drug Delivery System (IDDS)"

BRUNO, GIACOMO. "Leveraging nanochannels for a remotely controllable implantable drug delivery system." Doctoral thesis, Politecnico di Torino, 2017. http://hdl.handle.net/11583/2676478.

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This work is focused on the research on how to leverage nanochannels in the eld of Nanomedicine. More speci cally the study of different diffusion regimes at the nanoscale thanks to the close collaboration between the Politecnico di Torino, Turin, Italy, and the Methodist Hospital Research Institute, Houston, Texas. The therapeutics ow through nanochannels can be tightly controlled by several factors such as channels dimension, channel polarity, solution ionic strength just to name a few. The major advantage of this nanotechnology is that the drug ow results to be linear over time and pract

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Holmberg, Alexander. "Developing an implantable drug delivery system for ecological studies on fish." Thesis, Umeå universitet, Institutionen för integrativ medicinsk biologi (IMB), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-169961.

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SILVESTRI, ANTONIA. "Implantable Nanofluidic Membrane and Smart Electronic System for Drug Release Control." Doctoral thesis, Politecnico di Torino, 2021. http://hdl.handle.net/11583/2918000.

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Tsao, Chih-Hao, and 曹志豪. "Application of Ionic Polymer-Metal Composites (IPMC) Actuator Application of Ionic Polymer-Metal Composites (IPMC) Actuatr for Implantable Drug Delivery System." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/78109324905158746112.

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碩士<br>中原大學<br>醫學工程研究所<br>97<br>Ionic polymer-metal composites (IPMC) are a kind of electroactive polymer (EAP) that has been used for various applications, such as artificial muscles, sensors and actuators, because of its light weight and ability to make more than 100% bending deformation under low driving voltage. In this study, an IPMC actuator was incorporated into a self-designed device for application as an implantable drug delivery system. First, IPMC films with different thickness, dimensions and metal electrodes were constructed. The second step required a basic measurement of the IPMC

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Chapitres de livres sur le sujet "Implantable Drug Delivery System (IDDS)"

Upadhyay, S., S. Soni, T. Shukla, et al. "Implantable Drug Delivery System." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_6.

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Wang, Shen Guo, Qing Cai, Jian Zhong Bei, Wei Yun Shi, and Li Xin Xie. "An Implantable Immunosuppressive Cyclosporine Drug Delivery System." In Advanced Biomaterials VI. Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-967-9.125.

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Reynaerts, Dominiek, Jan Peirs, and Hendrik Van Brussel. "An Implantable Drug Delivery System Based on Shape-Memory Alloys." In Shape Memory Implants. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59768-8_23.

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Bonso, A., G. Gasparini, S. Themistoclakis, F. Giada, and A. Raviele. "Implantable Atrial Defibrillator: Why not a Patient-Activated Drug Delivery System?" In Cardiac Arrhythmias 1999 - Vol.1. Springer Milan, 2000. http://dx.doi.org/10.1007/978-88-470-2139-6_17.

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Athlin, L., M. Hagberg, and Y. Wahlqvist. "Central Venous Access in Children Through a Fully Implantable Drug Delivery System." In Progress in Regional Cancer Therapy. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74818-9_4.

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Raviele, A., F. Giada, G. Gasparini, S. Themistoclakis, A. Bonso, and A. Corrado. "Patient-Activated Implantable Drug Delivery System for Treatment of Vasovagal Syncope: A Simple Solution?" In Cardiac Arrhythmias 1999 - Vol.1. Springer Milan, 2000. http://dx.doi.org/10.1007/978-88-470-2139-6_64.

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Raviele, A., M. Brignole, C. Menozzi, F. Giada, and A. Dorigo. "Development of an Implantable Drug Delivery System for the Treatment of Vasovagal Syncope: a Dream or a Real Prospect?" In Cardiac Arrhythmias 1997. Springer Milan, 1998. http://dx.doi.org/10.1007/978-88-470-2288-1_55.

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Desai, Jagruti L., Pal B. Patel, Ashwini D. Patel, Richa R. Dave, Swayamprakash Patel, and Pranav Shah. "Implantable Drug Delivery." In Novel Drug Delivery Systems (Part 2). BENTHAM SCIENCE PUBLISHERS, 2024. https://doi.org/10.2174/9789815313567124010008.

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Miniaturized systems, known as implantable drug delivery systems, are used to administer medicinal medicines to specific sites within the body. They are made of biocompatible substances that enclose the drug payload and control its kinetics of release, enabling sustained delivery. These systems provide a number of benefits by avoiding the drawbacks of oral drugs and conventional injectable techniques, including increased bioavailability, fewer systemic side effects, and improved patient adherence. The key characteristics and elements of implanted drug delivery systems, such as the drug reservo

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Horine, Storm, Grant Chen, Shane Brogan, and Priyanka Ghosh. "Intrathecal Drug Delivery System." In Cancer Pain Procedural Techniques, edited by Amitabh Gulati, Neal Rakesh, Grant Chen, Storm Horine, Ali Valimahomed, and Ehtesham Baig. Oxford University PressNew York, 2025. https://doi.org/10.1093/med/9780190933500.003.0037.

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Abstract Intrathecal drug delivery systems (IDDS) are used for cancer patients with moderate to severe pain that is refractory to conservative therapies. IDDS therapy is approved for chronic use for both cancer-related pain and non-cancer-related pain. It has been demonstrated to provide excellent pain relief in both populations. However, IDDS can be an expensive and invasive treatment option that requires diligent follow-up and maintenance after implantation. Patient selection and physician familiarity with IDDS implantation are critical for clinical success. This chapter describes indication

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AJMAL, Dr GUFRAN. "IMPLANTABLE DRUG DELIVERY SYSTEMS." In NOVEL DRUG DELIVERY SYSTEM. GRF BOOKS, 2022. http://dx.doi.org/10.52458/9789391842871.2022.eb.grf.asu.ch.17.

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Actes de conférences sur le sujet "Implantable Drug Delivery System (IDDS)"

Del Bono, Fabiana, Nicola Di Trani, Danilo Demarchi, Alessandro Grattoni, and Paolo Motto Ros. "System Integration of an Implantable Drug Delivery Device for Long-Term In-Vivo Experiments." In 2024 IEEE SENSORS. IEEE, 2024. https://doi.org/10.1109/sensors60989.2024.10785116.

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Maloney, John M. "An Implantable Microfabricated Drug Delivery System." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43186.

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We report on the development of a fully implantable drug delivery system capable of delivering hundreds of individual doses. This product is intended for the controlled release of potent therapeutic compounds that might otherwise require frequent injections. Our system has the following capabilities: • Stable, hermetic storage of therapeutic drugs in solid, liquid, or gel form; • Individual storage of discrete doses for multiple-drug regimens; • Wireless communication with an external controller for device monitoring and therapy modification; • Choice of preprogrammed release or release on com

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Moussi, Khalil, Abdullah Bukhamsin, and Jurgen Kosel. "Implantable 3D Printed Drug Delivery System." In 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII). IEEE, 2019. http://dx.doi.org/10.1109/transducers.2019.8808496.

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Ding, Yiwen, and Panagiotis Kosmas. "Miniaturized Implantable Antenna for Drug Delivery System." In 4th URSI Atlantic RadioScience Conference. URSI – International Union of Radio Science, 2024. http://dx.doi.org/10.46620/ursiatrasc24/zvil1982.

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Sayeed, Md Abu, and Abu Shahed. "iDDS 2.0: An IoT-enabled Energy Efficient and Fast Drug Delivery System for Epilepsy." In 2023 IEEE International Conference on Consumer Electronics (ICCE). IEEE, 2023. http://dx.doi.org/10.1109/icce56470.2023.10043376.

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Smith, S. "An implantable drug delivery system with wireless power and communication." In IET Seminar on Bionic Health: Next Generation Implants, Prosthetics and Devices. IET, 2009. http://dx.doi.org/10.1049/ic.2009.0194.

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Maillefer, D., H. van Lintel, G. Rey-Mermet, and R. Hirschi. "A high-performance silicon micropump for an implantable drug delivery system." In Technical Digest. IEEE International MEMS 99 Conference. Twelfth IEEE International Conference on Micro Electro Mechanical Systems (Cat. No.99CH36291). IEEE, 1999. http://dx.doi.org/10.1109/memsys.1999.746886.

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Khorami, Ali, and Seyed Sajjad Alemi. "Designing a wireless power transfer harvester for on demand implantable drug delivery system." In 2021 28th National and 6th International Iranian Conference on Biomedical Engineering (ICBME). IEEE, 2021. http://dx.doi.org/10.1109/icbme54433.2021.9750340.

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Ridgeway, Shane, Junho Song, and Li Cao. "A Selectively Anodic Bonded Micropump for Implantable Medical Drug Delivery Systems." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33551.

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Microelectromechanical Systems (MEMS) fabrication techniques offer a unique solution for implantable medical drug delivery systems. An implantable medical drug delivery system can relieve the pain associated with frequent injections and deliver a localized dosage. An implantable drug delivery system can also avoid contamination and infection better than conventional injection methods (such as intravenous injection). The major advantage of microfabricated drug delivery systems is the possibility of mass production at low cost. A silicon based peristaltically actuated implantable medical drug de

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Guegan, Eric, Tian Davis, Thomas J. Koob, and Yvonne Moussy. "Transport Characteristics of a Novel Local Drug Delivery System Using Nordihydroguaiaretic Acid (NDGA)-Polymerized Collagen Fibers." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-171428.

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Local delivery of a drug in vivo would permit high interstitial drug concentration at the desired location without producing high systemic drug levels. Previous local drug delivery systems have included biodegradable polymer implants, hydrogels, and osmotic pumps [1]. In this paper, we describe a novel local drug delivery system using nordihydroguaiaretic acid (NDGA)-polymerized collagen fibers. NDGA collagen fibers were originally developed for use as biocompatible tendon bioprostheses [2]. The NDGA collagen fibers were loaded with either: dexamethasone, a synthetic glucocorticoid with anti-i

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