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Thèses sur le sujet « Imprinted »

Auteur : Grafiati

Publié le 1 avril 2023

Mis à jour le 31 juillet 2025

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1

Robak, Andrew Joseph. "Development of coenzyme-imprinted molecularly imprinted polymers as catalysts /." view abstract or download file of text, 2007. http://proquest.umi.com/pqdweb?did=1276397881&sid=1&Fmt=2&clientId=11238&RQT=309&VName=PQD.

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Thesis (Ph. D.)--University of Oregon, 2007.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 94-100). Also available for download via the World Wide Web; free to University of Oregon users.

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2

Bates, Ferdia. "Design and development of molecularly imprinted polymers and imprinted sensors." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/399170.

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Esta tesis se ha hecho principalmente para estudiar e investigar polímeros impresos (MIPs) con la intención de usarlos como sensores de larga vida. La línea de investigación de esta tesis es la dirigida a conseguir la integración de estas formaciones impresas dentro de una lengua electrónica (ET), que es la rama de especialización en la que se ha desarrollado principalmente este proyecto. Después de hacer una revisión de la literatura, que inicialmente se centraba en la aplicación de MIPs a un equipo electroquímico, un sensor voltamétrico impreso y un procedimiento sensitivo complementario, el

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3

Morán, Barroso Verónica Fabiola. "Identification and analysis of imprinted and non-imprinted genes in distal human chromosome 20q13." Thesis, University of Edinburgh, 2001. http://hdl.handle.net/1842/23130.

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This thesis describes work that arose from studies of the imprinting of <i>GNAS1,</i> on human chromosome 20q13. Null mutations in <i>GNAS1</i> cause the hormone-resistance syndrome pseudohpoparathyroidism type 1a (PHP1a). It was demonstrated that <i>GNAS1</i> is imprinted, as predicted from the anomalous inheritance of PHP1a, but that its allele-specific regulation is highly complex. This gene is shown to encode several protein products: (i) the alpha subunit of the stimulatory G protein G<sub>s</sub>; this protein is biallelically derived; (ii) NESP55, a neuroendocrine secretory protein, exp

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4

O'Donnell, Elizabeth Anne. "Water-compatible molecularly imprinted polymers." Thesis, University of Strathclyde, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.438467.

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Canfarotta, Francesco. "Molecularly imprinted nanoparticles for diagnostic applications." Thesis, University of Leicester, 2016. http://hdl.handle.net/2381/37775.

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Molecularly imprinted polymers (MIP) are gaining increasing interest thanks to their low cost of manufacturing, robustness and stability compared to their bio-analogues such as antibodies. The molecular imprinting process can be defined as the generation of molecular recognition sites in a synthetic polymer. The template-derived sites thus created within the polymeric matrix allow MIPs (often referred as plastic antibodies, due to their synthetic nature) to selectively recognise and bind the target molecule. In light of these properties, MIPs have been successfully applied in sensors, assays a

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6

Bonini, Francesca. "Molecularly imprinted polymers for protome analysis." Thesis, Cranfield University, 2008. http://dspace.lib.cranfield.ac.uk/handle/1826/2716.

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Fast and efficient methods for the detection of insurgence and progression of diseases are at the basis of modern diagnostics and medicine. In this concern, biomarkers represent a powerful diagnostic tool, as their expression profiles well correlate with the pathology progression. Thus, the pathological state could be diagnosed by measuring the altered presence of a biomarker. In this direction, conspicuous help has been given by proteomics, intended as the study of the protein pattern of a sample and most frequently performed by two-dimensional electrophoresis. Although the proteome approach

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7

Mistry, Reena. "Niacinamide analysis using molecularly imprinted polymers." Thesis, University of British Columbia, 2002. http://hdl.handle.net/2429/43182.

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The objectives of this research were to use molecularly imprinted polymers (MIP) and microfluidic chips as an approach to a rapid and low cost analytical method for niacinamide analysis. Lab-on-a-chip (microfluidics) devices are becoming increasingly popular due to their relatively low cost, sensitivity, and speed. MIPs may be able to serve as solid-phase extraction packing material in microfluidic chips. To reach the objectives, it was necessary to identify the mechanisms by which binding of analyte to polymer occur, determine the optimal functional monomer to cross-linker ratio, and gain

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8

Mak, Wing Yin Winifred. "Developmental regulation of imprinted X inactivation." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407945.

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9

Wang, Jinfang. "Xanthine-imprinted polymers for decaffeination applications." Thesis, University of Strathclyde, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431777.

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10

Abd, Bashar H. "Molecularly imprinted polymers for drug delivery." Thesis, University of Leicester, 2018. http://hdl.handle.net/2381/43042.

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Molecularly imprinted polymers (MIP) have received much attention and increased interest thanks to their excellent cost efficiency, robustness, high selectivity and simple short synthesis. The molecular imprinting process can be defined as creation of molecular recognition sites in a synthetic polymer. The template-derived sites thus created within the polymeric matrix allow MIP to selectively recognise and bind the target molecule. In light of these properties, MIP have been successfully applied in sensors, assays separation, and for drug delivery applications. Because of their small size, MI

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11

Dent, Claire. "Imprinted genes, impulsivity and risk-taking." Thesis, Cardiff University, 2014. http://orca.cf.ac.uk/66461/.

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genes show monoallelic parent-of-origin specific expression and have an important role in mediating adult behaviour. Previous research has indicated that maternally expressed Nesp and paternally expressed Grb10, which are expressed in overlapping brain regions, may have a role in mediating risk-taking and/or impulsive behaviours. Impulsivity and risk taking are natural parts of human behaviour; however pathological levels of impulsivity and risk-taking are recognised as clinical traits of many psychiatric disorders. The aim of the current research is to explicitly test whether these two opposi

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12

Silva, Matteo. "Interactions in optically imprinted polariton lattices." Thesis, University of Southampton, 2017. https://eprints.soton.ac.uk/415858/.

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Microcavity exciton-polaritons results from the admixture of cavity photons and excitons in the strong coupling regime. Due to their hybrid nature, polaritons are a promising solid-state platform for both fundamental studies on light-matter interaction and applications in quantum and opto-electronics technologies. In this thesis, optically imprinted graphs of interacting polariton condensates are proposed and demonstrated to simulate universal spin models whose ground state brings about the solution of a bespoken optimisation task. The establishment, control and tailoring of a complex network

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13

Whetton, Stephen. "Novel imprinted polymers as artificial enzymes." Thesis, Aston University, 2001. http://publications.aston.ac.uk/9644/.

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Derivatives of L-histidine were investigated as suitable models for the Asp-His couple found in the catalytic triad of serine proteases. A combination of molecular dynamics and IH NMR spectroscopy suggested that the most populous conformations of N-acetyl-L-histidine and the N-acetyl-L-histidine anion were predominated by those in which the carboxylate group was gauche to the imidazole ring overcoming steric and electrostatic repulsion, suggesting there is an interaction between the carboxylate group and the imidazole ring. Kinetic studies, using imidazole, N-acetyl-L-histidine and the N-acety

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14

Alam, Shadab. "Mysteries of Universe Imprinted on Redshifts." Research Showcase @ CMU, 2016. http://repository.cmu.edu/dissertations/992.

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15

Hu, Lucy Yue. "Binding studies on molecularly imprinted polymers." W&M ScholarWorks, 2004. https://scholarworks.wm.edu/etd/1539623453.

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Molecular imprinting is a rapidly developing technique for preparation of polymeric materials that are capable of molecular recognition for selective separation and chemical identification. to prepare molecularly imprinted polymers (MIPs), a functional monomer and a crosslinker are polymerized in the presence of a template molecule. Then the template is extracted leaving sites which are complementary in both shape and chemical functionality to those of the template. This resin then becomes capable of selectively absorbing the template species. Because of MIPs' stability, predesigned selectivit

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Tshikhudo, Tshinyadzo Robert. "Development of nickel-selective molecularly imprinted polymers." Thesis, Rhodes University, 2002. http://hdl.handle.net/10962/d1004449.

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A series of eight novel bidentate ligands, designed for use in the construction of nickel-selective molecularly imprinted polymers (MIP's), have been prepared. The synthetic pathway was established by retrosynthetic analysis of the target molecules to the readily available precursors, pyridine-2-carbaldehyde (or 6-methylpyridine-2-carbaldehyde) and ethyl bromoacetate. The ligands were designed to contain an allyl group for co-polymerisation and amine and pyridyl nitrogen donors, located to permit the formation of 5-membered nickel chelates. The eight novel ligands and their respective precurso

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17

Mandadi, Deepika. "A Characterization of Caffeine Imprinted Polypyrrole Electrode." TopSCHOLAR®, 2009. http://digitalcommons.wku.edu/theses/130.

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Nanotechnology holds great potential for improving our lives by creating many new materials and devices in medical sciences, electronics and also in energy production. Molecularly imprinted polymers (MIPs) are highly stable synthetic polymers that possess molecular recognition properties due to cavities created in the polymer matrix that are complementary to an analyte both in shape and in positioning of functional groups. These MIPs have been widely employed for diverse applications (e.g., in chromatographic separation, drug screening, chemosensors, catalysis, immunoassays etc) due to their s

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18

Judson, Hannah. "Investigation of candidate imprinted tumour suppressor genes." Thesis, University of Edinburgh, 2001. http://hdl.handle.net/1842/28316.

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Imprinting is an epigenetic phenomenon that silences one allele of a gene, so that expression in one or more cell types is exclusively monoallelic, and dependent on parental origin. Approaches used to identify novel imprinted genes rely on characteristic features such as the clustering of imprinted genes, or their association with differentially methylated CpG islands. An imprinted tumour suppressor gene involved in pathogenesis of neuroblastoma is believed to lie within chromosome 1p36. In this region, a search was initiated for imprinted genes in the vicinity of the imprinted gene <i>TP73.</

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19

Rick, John Frank. "Molecularly imprinted polymers as biological receptor analogues." Thesis, University of East Anglia, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249781.

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20

Kearton, Brian L. "Controlled free radical cyclisations in imprinted polymers." Thesis, University of Nottingham, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367355.

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21

Noyes, Karen Lynn 1977. "Synthesis and evaluation of actinide imprinted resins." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/30012.

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Thesis (Sc. D.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 2003.<br>Includes bibliographical references (p. 143-146).<br>Organic resins have previously shown good results with application to actinide separations. Large portions of recent research have been dedicated to the synthesis and evaluation of resins with phenolic-type functional groups. Other recent chemical research with lighter metals has developed a technique known as ion imprinting which can provide greater selectivity for the target metal ion. Initial work with ion imprinting and phenolic-type resins has

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22

Corman, M. E., C. Armutcu, L. Uzun, R. Say, and A. Denizli. "L-Lysine Imprinted Nanoparticles for Antibody Biorecognition." Thesis, Sumy State University, 2012. http://essuir.sumdu.edu.ua/handle/123456789/35007.

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The aim of this study was to prepare L-lysine-imprinted poly(HEMA-MAAsp) nanoparticles which can be used for the adsorption of IgG from aqueous solutions. L-lysine was complexed with MAAsp and Llysine- imprinted poly(HEMA-MAAsp) nanoparticles were synthesized by miniemulsion polymerization. Also, non-imprinted nanoparticles were synthesized without L-lysine for control purpose. L-lysine-imprinted poly(HEMA-MAAsp) nanoparticles were characterized by means of elemental analysis, Fourier transform infrared spectroscopy (FTIR) and transmission electron microscopy (TEM). When you are citing th

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23

Li, Bin. "Molecularly imprinted polymers for applications in cosmetology." Thesis, Compiègne, 2013. http://www.theses.fr/2013COMP2083.

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Un polymère à empreintes moléculaires (MIP) est un récepteur synthétique supramoléculaire, un matériau possédant des cavités pouvant reconnaître spécifiquement une molécule cible. Il est synthétisé en mettant en contact la molécule cible, avec un mélange de monomères fonctionnels et réticulants qui permettent d'obtenir un réseau polymérique tridimensionnel rigide. L'élimination de la molécule empreinte laissera des sites vides complémentaires de cette dernière. Ces cavités sont maintenant capables de la recapturer spécifiquement. Ces polymères sont utilisés dans les domaines tels que l’extract

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24

Shi, Huaiqiu Galen. "Protein recognition of template imprinted polymer surfaces /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/8075.

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25

Joshi, V. P. "Transport and reactions in molecularly imprinted polymers." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1998. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3397.

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26

Minor, Agata. "DNA methylation at imprinted and non-imprinted genes in the sperm of men affected by severe male factor infertility." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/29282.

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Abnormal DNA methylation at imprinted and non-imprinted genes has been associated with spermatogenesis failure. However, little information is available regarding DNA methylation at those genes in men affected by severe male factor infertility. We hypothesized a higher incidence of aberrant DNA methylation would be present in the ejaculate and testicular sperm of men affected by severe male factor infertility compared to that in fertile control men. Furthermore, we hypothesized abnormal DNA methylation would also affect non-imprinted genes in the sperm of men affected by severe oligozoospermia

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27

Mohammad, Faizaan. "Long Noncoding RNA Mediated Regulation of Imprinted Genes." Doctoral thesis, Uppsala universitet, Institutionen för genetik och patologi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-128882.

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Genomic imprinting is an epigenetic phenomenon that causes a subset of mammalian genes to be expressed from only one allele in a parent-of-origin manner. The defects in the imprinting regulation result in disorders that affect development, growth and metabolism. We have used the Kcnq1 imprinted cluster as a model to understand the mechanism of imprinted gene regulation. The imprinting at the Kcnq1 locus is regulated by a long noncoding RNA, Kcnq1ot1, whose transcription on the paternal chromosome is associated with the silencing of at least eight neighboring genes. By destabilizing Kcnq1ot1 in

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28

Myint, Mo Aung, and n/a. "Investigation of molecular interactions with molecularly imprinted polymers." University of Otago. Department of Chemistry, 2009. http://adt.otago.ac.nz./public/adt-NZDU20090617.131516.

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Currently, very little information is available for an in-depth understanding of the molecular binding interactions with molecularly imprinted polymers (MIPs). To address this issue MIPs that have high binding affinities for their template compounds were made so that the nature of these interactions could be elucidated using spectroscopic techniques. 12 functional MIPs were prepared using a series of azobenzene and anthracenyl derivatives as the templates. Affinities of these MIPs for the corresponding templates and analogues were determined by performing batch and competitive binding tests.

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29

Bourque, Danielle Kathleen. "Imprinted genes in the placenta and obstetrical complications." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/25509.

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Each year, many pregnancies are associated with obstetrical complications such as maternal pre-eclampsia (PET) and fetal intrauterine growth restriction (IUGR). Poor placentation is thought to contribute to these complications, but specific causes are largely unknown. Mouse models suggest that epigenetic mechanisms, in particular genomic imprinting, that alter gene regulation may help regulate placental development and embryonic growth. The first goal of this thesis is to examine if epigenetic modifications (i.e. DNA methylation) and altered expression of imprinted genes in the human placenta

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30

Holmes, Rebecca Jane. "Analysis of a novel cluster of imprinted genes." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270370.

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Bowen, Jenna Louise. "Detection of lipopolysaccharide pyrogens by molecularly imprinted polymers." Thesis, Cardiff University, 2011. http://orca.cf.ac.uk/54444/.

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Lipopolysaccharide (LPS) is commonly implicated in the development and rapid progression of sepsis however no efficient diagnostic assay currently exists. The over-arching aim of this project was therefore to develop a novel biomimetic peptide-polymer hybrid system capable of recognising and binding LPS in a variety of biologically relevant environments. Target selective peptides (both commercially available and synthesised) have been used as high affinity 'functional monomers' in a molecular imprinting approach. To reduce the concept to practice, a bi-functionalised resin was prepared so as t

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Wood, Andrew James. "The identificaiton and characterisation of novel imprinted genes." Thesis, University of London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498013.

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33

McEwen, Kirsten Rose. "Epigenetic regulation of imprinted loci in the mouse." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609297.

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34

Nativio, Raffaella. "Chromatin conformation at the IGF2-H19 imprinted locus." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609006.

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35

Ottway, Charlotte Jane. "Characterisation of Nespas, a non-coding imprinted RNA." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:b159c1e9-8d49-460c-a808-d920e8e17779.

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Nespas is the non-coding antisense transcript of the imprinted Gnas cluster; it is expressed from the paternal allele and is located on mouse distal chromosome 2. In this thesis new transcripts of >10 kb and 0.8 kb have been identified. The 0.8 kb transcript is a spliced variant that is retained in the nucleus and its 3’ end lies approximately 30 kb from the start site. Transcription from the Nespas promoter does not proceed beyond this point. A collection of previously known splice variants have also been detected and are exported to the cytoplasm. Nespas is expressed in the embryo during the

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Ritt, Cody. "Assessment of Molecularly Imprinted Polymers as Phosphate Sorbents." Thesis, North Dakota State University, 2017. https://hdl.handle.net/10365/28417.

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Wastewater effluents and agricultural runoff are major sources of phosphorus overloading in surface waters. Phosphorus overloading ignites eutrophication, which devastates aquatic ecosystems. On the other hand, phosphorus, which is currently produced from phosphate rock, is a critical component of fertilizer mixes. However, the world is predicted to face a shortage of phosphate supply beyond 2033 due to unsustainable mining. This research aims to develop a polymeric sorbent that recovers low-concentration phosphorus for eutrophication prevention and fertilizer reuse. Available polymer-based pr

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Ali, Aisha. "Synthesis and characterisation of imprinted polymeric receptor mimics." Thesis, Aston University, 2005. http://publications.aston.ac.uk/11027/.

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Molecularly imprinted polymers (MIPs) are crosslinked polymers containing bespoke functionalised cavities arising from the inclusion of template molecules in the polymerisation mixture and their later extraction. When the polymers are prepared functional polymerisable monomers are included which become part of the polymer matrix and serve to decorate the cavities with functionality appropriate to the template molecules. Overall, binding sites are created which have a memory for the template both in terms of shape and matching functionality. Fluorescent molecularly imprinted polymers have the b

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Leibl, Nadja. "Development of molecularly imprinted polymers for chemical sensors." Thesis, Compiègne, 2018. http://www.theses.fr/2018COMP2446.

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Cette thèse propose une approche rationnelle pour le design de polymères à empreintes moléculaires (MIPs) pour la détection de nitro-explosifs. Les polymères à empreintes moléculaires qui miment la reconnaissance moléculaire biologique, ont l’avantage d’être stables dans des environnements sévères et peuvent adopter différentes formes physiques pour le couplage avec des transducteurs. Leur synthèse est basée sur la co-polymérisation de monomères fonctionnels et réticulants en présence de la molécule cible, ou comme dans cette thèse, d’un analogue ayant une structure proche de celle de la moléc

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Martucci, Mariane Ferracin. "Impactos das biotécnicas reprodutivas no controle epigenético de genes imprinted." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/10/10132/tde-20102015-082930/.

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Técnicas de reprodução assistida (TRAs) são utilizadas tanto na medicina humana quanto na medicina veterinária com o objetivo principal de corrigir infertilidades adquiridas ou herdadas. A transferência nuclear de célula somática (TNCS) ocupa um lugar de destaque na veterinária pela possibilidade de geração de indivíduos geneticamente idênticos, permitindo a produção de rebanhos homogêneos de alto mérito genético e servindo como modelo de estudo para técnicas de reprogramação. Porém, a utilização de TRAs, e em especial da TNCS, é considerada responsável pelo aumento na geração de conceptos por

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Eppler, Stefan [Verfasser]. "Advanced strategies for characterizing molecular imprinted polymers / Stefan Eppler." Ulm : Universität Ulm. Fakultät für Naturwissenschaften, 2014. http://d-nb.info/1052586007/34.

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Bolisay, Linden De Venecia. "Molecularly imprinted polymers for the recognition of tobacco viruses." College Park, Md. : University of Maryland, 2007. http://hdl.handle.net/1903/7277.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2007.<br>Thesis research directed by: Chemical Engineering. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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MacIsaac, Julia Lynn. "Developmental consequences of imprinted transcription at the Mest locus." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/44537.

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The Mest locus is regulated by genomic imprinting in mammals and only the paternally inherited allele is expressed. A targeted mutation at this locus revealed that it plays an important role in the regulation of embryonic growth and adult behavior. The Mest locus is located in a conserved imprinted domain on mouse chromosome 6 where it is thought to play a key role in the regulation of neighboring maternally expressed genes Copg2 and Klf14 since it contains the only potential imprinting center (IC) identified thus far in this domain, a differentially methylated region (DMR) methylated in oogen

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Davies, Matthew Paul. "The use of molecularly imprinted polymers in pharmaceutical analysis." Thesis, Queen Mary, University of London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408545.

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Revill, Kate. "Characterisation of the Imprinted Gene Neuronatin in Pituitary Tumorigensis." Thesis, Keele University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502941.

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Baker, J. "Identifying imprinted genes on mouse chromosome 12 : novel approaches." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596277.

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The distal portion of mouse chromosome 12 (chr.12) has been shown to be imprinted through translocation studies, with both maternal and paternal duplications and deficiencies causing embryonic lethality. The region shares homology primarily with human chromosome 14. An imprinted disorder has been attributed to maternal duplication/paternal deficiency of human chromosome 14 commonly referred to as maternal uniparental disomy (mUPD14). mUPD14 results in short stature, premature puberty, development delay, small hands with hyperextensible joints and other minor anomalies. These pieces of evidence

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46

Coar, Elizabeth Anne. "Mapping candidate control elements at the Gnas imprinted locus." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.615171.

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Allen, Sarah Elizabeth. "The role of an imprinted microRNA in mouse development." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608248.

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Kirsch, Nicole. "Molecular recognition of poorly functionalised molecules with imprinted polymers." Thesis, University of Reading, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325167.

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Le, Strat LoiÌˆc. "Imprinted polymers and templated cyclic peptides : a combinatorial approach." Thesis, University of Southampton, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274468.

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Ishida, M. "The role of imprinted genes in human fetal growth." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1348482/.

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Identifying the genes important for fetal growth will help to understand common, serious complications of pregnancy such as intrauterine growth restriction (IUGR). Of particular interest are imprinted genes, which show monoallelic, parent-of-origin specific expression. Genes that are paternally derived tend to enhance fetal growth whereas maternally expressed genes suppress growth. A significant correlation between lower birth weight and increased expression of maternally expressed, pleckstrin homology-like domain, family A, member 2 (PHLDA2) in term placenta, without loss of imprinting, had b

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