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1

Yen, Nguyen Thi Hai, Le Duc Anh, Hoang Anh Tuan, and Nguyen Toan Thang. "Mott Transition in the Mass Imbalanced Ionic Hubbard Model at Half Filling." Communications in Physics 29, no. 3SI (2019): 305. http://dx.doi.org/10.15625/0868-3166/29/3si/14265.

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The Mott - Hubbard metal - insulator transition in the half-filled mass imbalanced ionic Hubbard model is investigated using the two-site dynamical mean field theory. We find that for a fixed mass imbalanced parameter r the critical interaction Uc increases when the ionic energy \(\Delta\) is increased. In the other hand, for a fixed \(\Delta\), \(U_c\) decreases with increasing the mass imbalance. We also show the existence of BI phase in the system for the case \(\Delta \ne 0\), \(U=0\) and calculate the staggered charge density \(n_B − n_A\) as a function of the interaction for different va
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Lin, Jiaqi, and Alfredo Alexander-Katz. "Probing Lipid Bilayers under Ionic Imbalance." Biophysical Journal 111, no. 11 (2016): 2460–69. http://dx.doi.org/10.1016/j.bpj.2016.10.006.

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PIE, G., and M. CZUBRYT. "The contribution of ionic contribution of ionic imbalance to ischemia/reperfusion-induced injury." Journal of Molecular and Cellular Cardiology 27, no. 1 (1995): 53–63. http://dx.doi.org/10.1016/s0022-2828(08)80007-7.

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Noguchi, Izumi, and Hiroshi Hara. "Ionic imbalance due to hydrogen carbonate from Asian dust." Atmospheric Environment 38, no. 40 (2004): 6969–76. http://dx.doi.org/10.1016/j.atmosenv.2004.03.077.

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Ikeda, Yoko, Hideya Nakamura, Shuji Ohsaki, and Satoru Watano. "Direct translocation of a negatively charged nanoparticle across a negatively charged model cell membrane." Physical Chemistry Chemical Physics 23, no. 17 (2021): 10591–99. http://dx.doi.org/10.1039/d0cp06278b.

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Coggan, J. S., S. A. Prescott, T. M. Bartol, and T. J. Sejnowski. "Imbalance of ionic conductances contributes to diverse symptoms of demyelination." Proceedings of the National Academy of Sciences 107, no. 48 (2010): 20602–9. http://dx.doi.org/10.1073/pnas.1013798107.

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El Banani, Houda, Monique Bernard, Patrick Cozzone, Françoise James, and Danielle Feuvray. "Ionic and metabolic imbalance as potential factors of ischemia reperfusion injury." American Journal of Cardiology 82, no. 5 (1998): 25K—29K. http://dx.doi.org/10.1016/s0002-9149(98)00534-7.

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Douglas, W. S., and S. S. Grasso. "Ionic Imbalance as a Source of Toxicity in an Estuarine Effluent." Archives of Environmental Contamination and Toxicology 31, no. 3 (1996): 426–32. http://dx.doi.org/10.1007/s002449900128.

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Douglas, W. S., S. S. Grasso, D. G. Hutton, and K. R. Schroeder. "Ionic imbalance as a source of toxicity in an estuarine effluent." Archives of Environmental Contamination and Toxicology 31, no. 3 (1996): 426–32. http://dx.doi.org/10.1007/bf00212683.

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Ren, Yuan, Bo Liu, Bing He, et al. "Portraying the ionic transport and stability window of solid electrolytes by incorporating bond valence-Ewald with dynamically determined decomposition methods." Applied Physics Letters 121, no. 17 (2022): 173904. http://dx.doi.org/10.1063/5.0117286.

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Designing inorganic solid electrolytes (ISEs) with both excellent electrochemical stability and high ionic conductivity is an important research direction for all-solid-state batteries. However, due to the electronic conduction of hierarchical decomposition products, there is an imbalance between the ionic transport and electrochemical stability window of the ISEs. Here, we propose a computational approach that incorporates bond valence-Ewald energy analysis and dynamically determined decomposition pathway to portray the competing relationship between ionic transport and stable electrochemical
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Almora, Osbel, Antonio Guerrero, and Germà Garcia-Belmonte. "Ionic charging by local imbalance at interfaces in hybrid lead halide perovskites." Applied Physics Letters 108, no. 4 (2016): 043903. http://dx.doi.org/10.1063/1.4941033.

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Proskurina, E. Yu, and A. V. Zaitsev. "Regulation of Potassium and Chloride Concentrations in Nervous Tissue as a Method of Anticonvulsant Therapy." Journal of Evolutionary Biochemistry and Physiology 58, no. 5 (2022): 1275–92. http://dx.doi.org/10.1134/s0022093022050015.

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Abstract Under some pathological conditions, such as pharmacoresistant epilepsy, status epilepticus or certain forms of genetic abnormalities, spiking activity of GABAergic interneurons may enhance excitation processes in neuronal circuits and provoke the generation of ictal discharges. As a result, anticonvulsants acting on the GABAergic system may be ineffective or even increase seizure activity. This paradoxical effect of the inhibitory system is due to ionic imbalances in nervous tissue. This review addresses the mechanisms of ictal discharge initiation in neuronal networks due to the imba
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Srivastava, Jatin, Harish Chandra, and Nandita Singh. "Seasonal Variation In Ionic Fluxing In The Fresh Water Bodies Of Lucknow City Of U.P. (India)." Environment Conservation Journal 7, no. 1&2 (2006): 59–63. http://dx.doi.org/10.36953/ecj.2006.071210.

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Surface water of natural wetlands of Lucknow city was monitored as a part of comprehensive study of natural imbalance of nutrient ions such as PO4 , NO3, Cl and NH4. The common seasonal changes were recorded and statistically analyzed exhibiting a correlation of parameters and also the dependency of one on another. In summer where there is a loss of water due to evaporation results in more ionic concentrations, however, the rainy and winter seasons receives a different chemistry after a average spell of rain. Overall study presents a seasonal variation in the ionic species in water and its imp
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14

Weiland, Lisa Mauck, and Donald J. Leo. "Ionic polymer cluster energetics: Computational analysis of pendant chain stiffness and charge imbalance." Journal of Applied Physics 97, no. 12 (2005): 123530. http://dx.doi.org/10.1063/1.1937475.

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Sundaram, M., E. M. Shankar, C. N. Srinivas, S. Solomon, P. Balakrishnan, and N. Kumarasamy. "Can ionic imbalance in HIV disease be attributed to certain underlying opportunistic infections?" Indian Journal of Clinical Biochemistry 25, no. 1 (2010): 105–7. http://dx.doi.org/10.1007/s12291-010-0002-5.

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Campbell, Jacob B., Mads Kuhlmann Andersen, Johannes Overgaard, and Jon F. Harrison. "Paralytic hypo-energetic state facilitates anoxia tolerance despite ionic imbalance in adultDrosophila melanogaster." Journal of Experimental Biology 221, no. 12 (2018): jeb177147. http://dx.doi.org/10.1242/jeb.177147.

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Guo, Rui, Ji Zhou, WeiPing Hao, et al. "Germination, growth, photosynthesis and ionic balance in Setaria viridis seedlings subjected to saline and alkaline stress." Canadian Journal of Plant Science 91, no. 6 (2011): 1077–88. http://dx.doi.org/10.4141/cjps10167.

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Guo, R., Zhou, J., Hao, W., Gong, D., Zhong, X., Gu, F., Liu, Q., Xia, X., Tian, J. and Li, H. 2011. Germination, growth, photosynthesis and ionic balance in Setaria viridis seedlings subjected to saline and alkaline stress. Can. J. Plant Sci. 91: 1077–1088. Setaria viridis seeds and seedlings were subjected to saline and alkaline stress to determine their effects on germination and growth indices, and physiological parameters. The treatments consisted of solutions of NaCl:Na2SO4 for saline stress and NaHCO3:Na2CO3 for alkaline stress, at different concentrations. Germination, growth, photosyn
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Sadegh-Zadeh, Seyed-Ali, Chandrasekhar Kambhampati, and Darryl Davis. "Ionic Imbalances and Coupling in Synchronization of Responses in Neurons." J 2, no. 1 (2019): 17–40. http://dx.doi.org/10.3390/j2010003.

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Most neurodegenerative diseases (NDD) are a result of changes in the chemical composition of neurons. For example, Alzheimer’s disease (AD) is the product of Aβ peptide deposition which results in changes in the ion concentration. These changes in ion concentration affect the responses of the neuron to stimuli and often result in inducing excessive excitation or inhibition. This paper investigates the dynamics of a single neuron as ion changes occur. These changes are incorporated using the Nernst equation. Within the central and peripheral nervous system, signals and hence rhythms, are propag
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Pelin, M., C. Zanette, M. De Bortoli, et al. "Effects of the marine toxin palytoxin on human skin keratinocytes: Role of ionic imbalance." Toxicology 282, no. 1-2 (2011): 30–38. http://dx.doi.org/10.1016/j.tox.2011.01.010.

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Cisterna, Bruno A., Aníbal A. Vargas, Carlos Puebla, and Juan C. Sáez. "Connexin hemichannels explain the ionic imbalance and lead to atrophy in denervated skeletal muscles." Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1862, no. 11 (2016): 2168–76. http://dx.doi.org/10.1016/j.bbadis.2016.08.020.

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Bernard, M., H. El Banani, P. J. Cozzone, and D. Feuvray. "Ionic and metabolic imbalance in various conditions of ischemia-reperfusion: A31P- and23Na-NMR study." Magnetic Resonance Materials in Physics, Biology and Medicine 6, no. 2-3 (1998): 175–76. http://dx.doi.org/10.1007/bf02660951.

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22

Lin, Jiaqi, Roozbeh Dargazany, and Alfredo Alexander-Katz. "Lipid Flip-Flop and Pore Nucleation on Zwitterionic Bilayers are Asymmetric under Ionic Imbalance." Small 13, no. 22 (2017): 1603708. http://dx.doi.org/10.1002/smll.201603708.

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23

Adeva-Andany, María M., Natalia Carneiro-Freire, Cristóbal Donapetry-García, Eva Rañal-Muíño, and Yosua López-Pereiro. "The Importance of the Ionic Product for Water to Understand the Physiology of the Acid-Base Balance in Humans." BioMed Research International 2014 (2014): 1–16. http://dx.doi.org/10.1155/2014/695281.

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Human plasma is an aqueous solution that has to abide by chemical rules such as the principle of electrical neutrality and the constancy of the ionic product for water. These rules define the acid-base balance in the human body. According to the electroneutrality principle, plasma has to be electrically neutral and the sum of its cations equals the sum of its anions. In addition, the ionic product for water has to be constant. Therefore, the plasma concentration of hydrogen ions depends on the plasma ionic composition. Variations in the concentration of plasma ions that alter the relative prop
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24

Huang, Po-Wei, Bernd Flemisch, Chao-Zhong Qin, Martin O. Saar, and Anozie Ebigbo. "Validating the Nernst–Planck transport model under reaction-driven flow conditions using RetroPy v1.0." Geoscientific Model Development 16, no. 16 (2023): 4767–91. http://dx.doi.org/10.5194/gmd-16-4767-2023.

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Abstract. Reactive transport processes in natural environments often involve many ionic species. The diffusivities of ionic species vary. Since assigning different diffusivities in the advection–diffusion equation leads to charge imbalance, a single diffusivity is usually used for all species. In this work, we apply the Nernst–Planck equation, which resolves unequal diffusivities of the species in an electroneutral manner, to model reactive transport. To demonstrate the advantages of the Nernst–Planck model, we compare the simulation results of transport under reaction-driven flow conditions u
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25

Nunes, Paula, Isabelle Roth, Paolo Meda, Eric Féraille, Dennis Brown, and Udo Hasler. "Ionic imbalance, in addition to molecular crowding, abates cytoskeletal dynamics and vesicle motility during hypertonic stress." Proceedings of the National Academy of Sciences 112, no. 24 (2015): E3104—E3113. http://dx.doi.org/10.1073/pnas.1421290112.

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Cell volume homeostasis is vital for the maintenance of optimal protein density and cellular function. Numerous mammalian cell types are routinely exposed to acute hypertonic challenge and shrink. Molecular crowding modifies biochemical reaction rates and decreases macromolecule diffusion. Cell volume is restored rapidly by ion influx but at the expense of elevated intracellular sodium and chloride levels that persist long after challenge. Although recent studies have highlighted the role of molecular crowding on the effects of hypertonicity, the effects of ionic imbalance on cellular traffick
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26

Szabo, Marta Eva, Marie Therese Dro-Lefaix, and Michel Doly. "Modification of reperfusion-induced ionic imbalance by free radical scavengers in spontaneously hypertensive rat retina." Free Radical Biology and Medicine 13, no. 6 (1992): 609–20. http://dx.doi.org/10.1016/0891-5849(92)90035-f.

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Jung, Woo Hyuk, Sang Yup Lee, Yedam Lee, and Dong June Ahn. "Freezing-driven ionic charge imbalance leads to pore formation and osmotic injury of lipid membranes." Computers in Biology and Medicine 189 (May 2025): 109960. https://doi.org/10.1016/j.compbiomed.2025.109960.

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28

Brown, Ronald B. "Myopia, Sodium Chloride, and Vitreous Fluid Imbalance: A Nutritional Epidemiology Perspective." Epidemiologia 5, no. 1 (2024): 29–40. http://dx.doi.org/10.3390/epidemiologia5010003.

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Theories of myopia etiology based on near work and lack of outdoor exposure have had inconsistent support and have not prevented the rising prevalence of global myopia. New scientific theories in the cause and prevention of myopia are needed. Myopia prevalence is low in native people consuming traditional diets lacking in sodium chloride, and nutritional epidemiological evidence supports the association of rising myopia prevalence with dietary sodium intake. East Asian populations have among the highest rates of myopia associated with high dietary sodium. Similar associations of sodium and ris
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29

Al-Momany, Bayan, and Saeid Abu-Romman. "Cucumber and salinity." Australian Journal of Crop Science, no. 17(07):2023 (July 1, 2023): 581–90. http://dx.doi.org/10.21475/ajcs.23.17.06.p3915.

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Salinity is becoming more expanded globally. Soil salinity imposes a great challenge for vegetable-crops production in arid and semiarid regions. Cucumber (Cucumis sativus L.) is the fourth most important vegetable crop worldwide. In this review, we discuss the complex network of effects, and the ways cucumber responds to salinity. Salt stress inhibits almost all growth phases and yield components of cucumber. Accumulation of Na+ and/or Cl- ions in cucumber tissues disturbs the absorption of other ions causing ionic imbalance which affect stomatal opening. Nevertheless, high levels of NaCl in
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Yehorova, T. M. "Ecological and hydrochemical basis of formation of water basins of Polissia of Ukraine." Horticulture: Interdepartment Subject Scientific Collection, no. 79 (2024): 168–75. https://doi.org/10.35205/0558-1125-2024-79-168-175.

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The spatial correlation analysis of landscape-hydrochemical and biogeochemical parameters of river waters in the territory of Polissia was conducted. 9 hydrological sub-basins of the Dnipro river valley were studied. There are highlighted the new approaches and methods for information support of the basin principle of water resources management of Ukraine. The surface water subbasins of the territory of Polissia are characterized by the homogeneity of the macrocomponent composition of the waters, which is determined by their hydrocarbonate calcium type. However, the territories of the sub-basi
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Besancon, Elaine, Shuzhen Guo, Josephine Lok, Michael Tymianski, and Eng H. Lo. "Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke." Trends in Pharmacological Sciences 29, no. 5 (2008): 268–75. http://dx.doi.org/10.1016/j.tips.2008.02.003.

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Bernard, M. "Ionic and metabolic imbalance in various conditions of ischemia-reperfusion: A 31P- and 23Na-NMR study." Magnetic Resonance Materials in Biology, Physics, and Medicine 6, no. 2-3 (1998): 175–76. http://dx.doi.org/10.1016/s1352-8661(98)00058-1.

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dos Santos, Danielle Ferreira, and Bluma Guenther Soare. "Effect of Phosphonium-Based Ionic Liquid Content in Curing Epoxy Resin/Carbon Nanotubes Systems." Advanced Engineering Forum 46 (June 28, 2022): 15–21. http://dx.doi.org/10.4028/p-241zv9.

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The effect of varying the content of the ionic liquid based on phosphonium, tributyl (ethyl)-phosphonium diethylphosphate, was studied acting with a dual role as a curing and dispersing agent to obtain multiwalled carbon nanotube nanocomposites (MWCNT) dispersed in epoxy resin (ER). The effect of this ionic liquid in the mixtures was evaluated to obtain a better dispersion of the charge in the epoxy matrix, and consequently the impact on the curing of the nanocomposites. The effectiveness of the dispersion was evaluated morphologically by scanning electron microscopy (SEM). The non-covalent fu
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Hubschmann, Otakar R., and Douglas C. Nathanson. "The role of calcium and cellular membrane dysfunction in experimental trauma and subarachnoid hemorrhage." Journal of Neurosurgery 62, no. 5 (1985): 698–703. http://dx.doi.org/10.3171/jns.1985.62.5.0698.

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✓ Acute subarachnoid hemorrhage (SAH) and intraparenchymal hematoma (IPH) in cats are accompanied by massive cellular depolarization. This depolarization, characterized by potassium (K+) efflux and calcium (Ca++) influx, results in membrane destabilization, osmotic imbalance, and a decrease in electrical conduction. The Ca++ influx appears to initiate a chain reaction that, in some instances, may result in delayed cell destruction. The ionic dysequilibrium probably contributes to both brain engorgement and spasm in large vessels. The cellular depolarization and calcium-induced cell membrane in
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Tani, M. "Effects of anti-free radical agents on Na+, Ca2+, and function in reperfused rat hearts." American Journal of Physiology-Heart and Circulatory Physiology 259, no. 1 (1990): H137—H143. http://dx.doi.org/10.1152/ajpheart.1990.259.1.h137.

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The purpose of the present study was to determine whether the combined administration of superoxide dismutase (SOD) and catalase (CAT) or efforts to maintain the glutathione redox pathways with sulfhydryl agents could improve Na+ imbalance, reduce Ca2+ overload, and enhance recovery of function and metabolites upon reperfusion in isolated ischemic rat hearts, presumably by scavenging oxygen free radicals. After a 30-min exposure to zero-flow ischemia, left ventricular developed pressure (LVDP) and heart rate recovered to 31 and 81% of the preischemic value, respectively, ATP fell by approximat
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Akinmoladun, Afolabi Clement, Adesola Adebusayo Adelabu, Ibrahim Olabayode Saliu, Aanuoluwapo Ruth Adetuyi, and Mary Tolulope Olaleye. "Protective properties of Spondias mombin Linn leaves on redox status, cholinergic dysfunction and electrolyte disturbance in cyanide-intoxicated rats." Science Progress 104, no. 2 (2021): 003685042110118. http://dx.doi.org/10.1177/00368504211011866.

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Cyanide is an environmental neurotoxin which has been reported to arrest the normal functioning of the brain. This study investigated the protective properties of methanol and flavonoid-rich extracts of the leaves of Spondias mombin on redox status, cholinergic dysfunction and electrolyte disturbance in cyanide-induced neurotoxicity in rats. Male Wistar rats were orally pre-treated with Spondias mombin methanol leaf extract (SMC) (50, 100 and 150 mg/kg), flavonoid-rich extract (SMF) (25, 50 and 75 mg/kg) or quercetin (20 mg/kg), followed by intraperitoneal administration of 2 mg/kg potassium c
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De Pascale, Stefania, Francesco Orsini, Rosanna Caputo, Maria Antonella Palermo, Giancarlo Barbieri, and Albino Maggio. "Seasonal and multiannual effects of salinisation on tomato yield and fruit quality." Functional Plant Biology 39, no. 8 (2012): 689. http://dx.doi.org/10.1071/fp12152.

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The effects of short- and long-term salinisation were studied by comparing tomato growth on a soil exposed to one-season salinisation (short term) vs growth on a soil exposed to >20 years salinisation (long term). Remarkable differences were associated to substantial modifications of the soil physical-chemical characteristics in the root zone, including deteriorated structure, reduced infiltration properties and increased pH. Fresh yield, fruit number and fruit weight were similarly affected by short- and long-term salinisation. In contrast, the marketable yield was significantly lower in t
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Shahid, Muhammad Adnan, Ali Sarkhosh, Naeem Khan, et al. "Insights into the Physiological and Biochemical Impacts of Salt Stress on Plant Growth and Development." Agronomy 10, no. 7 (2020): 938. http://dx.doi.org/10.3390/agronomy10070938.

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Climate change is causing soil salinization, resulting in crop losses throughout the world. The ability of plants to tolerate salt stress is determined by multiple biochemical and molecular pathways. Here we discuss physiological, biochemical, and cellular modulations in plants in response to salt stress. Knowledge of these modulations can assist in assessing salt tolerance potential and the mechanisms underlying salinity tolerance in plants. Salinity-induced cellular damage is highly correlated with generation of reactive oxygen species, ionic imbalance, osmotic damage, and reduced relative w
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Shetty, Prateek, Margaret Mukami Gitau, and Gergely Maróti. "Salinity Stress Responses and Adaptation Mechanisms in Eukaryotic Green Microalgae." Cells 8, no. 12 (2019): 1657. http://dx.doi.org/10.3390/cells8121657.

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High salinity is a challenging environmental stress for organisms to overcome. Unicellular photosynthetic microalgae are especially vulnerable as they have to grapple not only with ionic imbalance and osmotic stress but also with the generated reactive oxygen species (ROS) interfering with photosynthesis. This review attempts to compare and contrast mechanisms that algae, particularly the eukaryotic Chlamydomonas microalgae, exhibit in order to immediately respond to harsh conditions caused by high salinity. The review also collates adaptation mechanisms of freshwater algae strains under persi
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Gurtovenko, Andrey A., and Ilpo Vattulainen. "Ion Leakage through Transient Water Pores in Protein-Free Lipid Membranes Driven by Transmembrane Ionic Charge Imbalance." Biophysical Journal 92, no. 6 (2007): 1878–90. http://dx.doi.org/10.1529/biophysj.106.094797.

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Choudhary, Arbind Kumar, and Sheela Devi Rathinasamy. "Effect of long intake of aspartame on ionic imbalance in immune organs of immunized wistar albino rats." Biomedicine & Aging Pathology 4, no. 3 (2014): 243–49. http://dx.doi.org/10.1016/j.biomag.2014.03.001.

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Cao, Changyu, Xingyi Zhu, Xiaowen Li, Huimin Ouyang, Kai Wang, and Xinran Li. "Assessment of ionic homeostasis imbalance and cytochrome P450 system disturbance in mice during fumonisin B1 (FB1) exposure." Chemosphere 251 (July 2020): 126393. http://dx.doi.org/10.1016/j.chemosphere.2020.126393.

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de las Heras, Natalia, Adrián Galiana, Sandra Ballesteros, et al. "Proanthocyanidins Maintain Cardiac Ionic Homeostasis in Aldosterone-Induced Hypertension and Heart Failure." International Journal of Molecular Sciences 22, no. 17 (2021): 9602. http://dx.doi.org/10.3390/ijms22179602.

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Excess aldosterone promotes pathological remodeling of the heart and imbalance in cardiac ion homeostasis of sodium, potassium and calcium. Novel treatment with proanthocyanidins in aldosterone-treated rats has resulted in downregulation of cardiac SGK1, the main genomic aldosterone-induced intracellular mediator of ion handling. It therefore follows that proanthocyanidins could be modulating cardiac ion homeostasis in aldosterone-treated rats. Male Wistar rats received aldosterone (1 mg kg−1 day−1) +1% NaCl for three weeks. Half of the animals in each group were simultaneously treated with th
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D, Barboza, Sambou P, Kane MM, et al. "Dysnatremia and Dyskaliaemia in Resuscitation: Epidemiological, Clinical, Therapeutic and Evolutionary Aspects." EAS Journal of Anaesthesiology and Critical Care 7, no. 01 (2025): 1–5. https://doi.org/10.36349/easjacc.2025.v07i01.002.

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Introduction: Ionic disorders are an imbalance between the ions entering and leaving the body. We studied dysnatremia and dyskaliaemia in patients admitted in resuscitation department. Patients and Method: This is a retrospective, descriptive and analytical study of dysnatremias and dyskaliaemias in patients hospitalized in the resuscitation department Peace Hospital of Ziguinchor from January 1st, 2021 to December 31th, 2021. The objectives were to assess the prevalence of these ionic disorders in resuscitation, to clarify the epidemiological profile, to identify clinical and paraclinical sig
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Munk, Petr, Zdeněk Tuzar, and Karel Procházka. "Donnan Equilibria in Polymeric Micellar Systems with Weak Polyelectrolyte Shells: The Lowering of the pH Value." Collection of Czechoslovak Chemical Communications 62, no. 11 (1997): 1730–36. http://dx.doi.org/10.1135/cccc19971730.

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When two electrolyte solutions are separated and only some of the ions can cross the boundary, the concentrations of these ions are different on both sides of the boundary. This is the well-known Donnan effect. When weak electrolytes are involved, the imbalance includes also hydrogen ions: there is a difference of pH across the boundary and the dissociation of nondiffusible weak electrolytes is suppressed. The effect is very pronounced when the concentration of the weak electrolyte is high and ionic strength is low. The significance of this phenomenon is discussed for polyelectrolyte solutions
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46

Alfaro, V., and L. Palacios. "Acute mild hypothermia in awake unrestrained rats induces a mixed acid-base disorder." Journal of Applied Physiology 80, no. 6 (1996): 2143–50. http://dx.doi.org/10.1152/jappl.1996.80.6.2143.

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The interactions between components that contribute to acid-base homeostasis were studied in the first steps of acute hypothermia [body temperature (Tb) 37-31 degrees C] in awake unrestrained rats as an experimental model of accidental hypothermia in mammals. The concurrent changes in blood gases, plasma ions, and plasma protein concentrations in arterial blood were analyzed. Acute decreases in Tb decreased PCO2 and increased pH. The ratio of Na+ concentration to Cl- concentration increased at 35-33 degrees C Tb, leading to an increase in the plasma strong ion difference ([SID]). These increas
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47

McFarland, Rebecca, Hadi S. Zanjani, Jean Mariani та Michael W. Vogel. "Changes in the Distribution of theα3 Na+/K+ATPase Subunit in Heterozygous Lurcher Purkinje Cells as a Genetic Model of Chronic Depolarization during Development". International Journal of Cell Biology 2014 (2014): 1–12. http://dx.doi.org/10.1155/2014/152645.

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A common assumption of excitotoxic mechanisms in the nervous system is that the ionic imbalance resulting from overstimulation of glutamate receptors and increased Na+and Ca++influx overwhelms cellular energy metabolic systems leading to cell death. The goal of this study was to examine how a chronic Na+channel leak current in developing Purkinje cells in the heterozygous Lurcher mutant (+/Lc) affects the expression and distribution of theα3 subunit of the Na+/K+ATPase pump, a key component of the homeostasis system that maintains ionic equilibrium in neurons. The expression pattern of the cat
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48

Santos, Cleiton Silva, Everton Cruz de Azevedo, Luciane Marieta Soares, et al. "Ionic imbalance and lack of effect of adjuvant treatment with methylene blue in the hamster model of leptospirosis." Memórias do Instituto Oswaldo Cruz 108, no. 4 (2013): 438–45. http://dx.doi.org/10.1590/s0074-0276108042013007.

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49

Samet, Halil, Yakup Çikili, and Aysun Çavuşoğlu. "Combined effects of excess boron and salinity on the growth and ionic imbalance of lavandin (Lavandula × intermedia) plant." Acta Scientiarum Polonorum Hortorum Cultus 22, no. 4 (2023): 91–103. http://dx.doi.org/10.24326/asphc.2023.5007.

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Generally, moderate to high salinity conditions and excess boron (B) occur together as limiting factors for plant growth in the soils of arid and semiarid regions. To determine the combined effect of excessive boron, salinity stress, or both, five different levels of B (0, 0.3, 0.6, 1.2, and 1.8 mM) and 80 mM sodium chloride (NaCl) were applied to lavandin plants grown in a greenhouse. The results showed that under nonsaline conditions, biomass production in shoots and roots and photosynthetic pigment contents (chlorophyll (Chl) a, b, and Chl a + b) decreased with exceptionally high B applicat
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Festa, Margherita, Velia Minicozzi, Anna Boccaccio, et al. "Current Methods to Unravel the Functional Properties of Lysosomal Ion Channels and Transporters." Cells 11, no. 6 (2022): 921. http://dx.doi.org/10.3390/cells11060921.

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A distinct set of channels and transporters regulates the ion fluxes across the lysosomal membrane. Malfunctioning of these transport proteins and the resulting ionic imbalance is involved in various human diseases, such as lysosomal storage disorders, cancer, as well as metabolic and neurodegenerative diseases. As a consequence, these proteins have stimulated strong interest for their suitability as possible drug targets. A detailed functional characterization of many lysosomal channels and transporters is lacking, mainly due to technical difficulties in applying the standard patch-clamp tech
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