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1

Md Tauhid Alam, Md Tanwir Alam, Jamal Akhtar, and Sultana Anjum. "EXPLORING THE PROPHET MUHAMMAD'S (PBUH) RECOMMENDATION OF KALONJI AND ITS RELEVANCE IN MODERN DISEASE MANAGEMENT: A COMPREHENSIVE REVIEW." International Journal of Islamic and Complementary Medicine 6, no. 1 (2025): 1–7. https://doi.org/10.55116/ijicm.v5i2.84.

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The seed of Nigella sativa Linn., known by various names like Small Black Seed, Black Cumin, and Kalonji, has a rich history in treating diverse ailments, as lauded by Prophet Mohammad (PBUH) for its healing properties against numerous diseases, except death, in Islamic and Arabic traditions. Rich in volatile oils, fixed oils, tannins, proteins, and essential amino acids, Kalonji finds extensive use in Unani medicine for conditions ranging from joint pain and indigestion to asthma, diabetes, and even cancer. This review synthesizes current literature to explore Kalonji's therapeutic potential,
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Kayes, M. I. B., S. Ahmed, C. A. Shabbir, S. Morshed, and M. S. Ali. "Nutritional profile and physicochemical analysis of two indigenous cultivars of black cumin (Nigella sativa) seeds and oil in Bangladesh." Food Research 8, no. 3 (2024): 293–99. http://dx.doi.org/10.26656/fr.2017.8(3).299.

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The black cumin (Nigella sativa) seed oil has a long history of use for food ingredients. The goal of this study is to figure out the nutritional and physicochemical properties of two indigenous black cumin cultivars (locally known as "Kali Jira" and "Kalonji") seed and oil. Additionally, the effects of extraction time and particle size on oil yield generation was investigated. The values of moisture content, crude protein content, crude fat, crude fiber, total ash, and carbohydrate of Kali Jira seed were 5.29%, 19.83%, 41.3%, 18.96%, 5.10%, and 9.52% whereas Kalonji had 5.43%, 19.95%, 40.3%,
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Thakur, Shifali, Hemlata Kaurav, and Gitika Chaudhary. "Nigella sativa (Kalonji): A Black Seed of Miracle." International Journal of Research and Review 8, no. 4 (2021): 342–57. http://dx.doi.org/10.52403/ijrr.20210441.

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It is recommended by the World health organization (WHO) that most of the world's population depends on herbal medicine for their health care. Nigella sativa is commonly known as a Black seed, Black cumin or 'Habbatul Barakah' i.e. an annual herb possessing a wide range of medicinal uses apart from its commercial significance as a spice yielding plant. It has long been used in the folk medicine system of the Arabian Gulf region, Far East Asia, and Europe. Seeds and oils of N. Sativa are the primary medicinal source from ancient times. It is one of the most common herbal plants used worldwide a
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Singh, Neeraj, Devi Singh, and C. John Wesley. "Genetic Variability of Black Cumin (Nigella sativa L.) under Climatic Condition of Prayagraj." International Journal of Plant & Soil Science 36, no. 6 (2024): 763–69. http://dx.doi.org/10.9734/ijpss/2024/v36i64681.

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An Experiment on Black cumin was conducted during September to March 2023-2024, in horticulture Research field, Department of Horticulture, Naini Agricultural Institute, Sam Higginbottom University of Agriculture, and Technology & Sciences Prayagraj(UP) India. The results of the investigation, regarding the performance of the 7 variety of black cumin i.e. NS-44, NS-32, Ajmer Nigella-1, Ajmer Nigella-20, Azad kalonji, Local variety -1, Local variety- 2 obtained from different sources to find out the best performance in terms of growth and yield in Prayagraj agro-climatic conditions. The exp
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Younus Khan, Furkhan, Mohammad Yasar, Mohammad Altamash, Shaikh Mukarram, Dr Rahil Meman, and Dr Molvi Khurshid. "An Overview of Skin Benefits of Black Seeds (Kalonji)." International Journal of Research in Pharmacy and Allied Science 04, no. 05 (2025): 104–19. https://doi.org/10.71431/ijrpas.2025.4510.

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Black seed (Nigella Sativa) is an annual flowering plant from the Ranunculaceae family, native to southwest Asia. The plant has many food and medicinal uses. The use of its seeds and oil is common for treatment of many diseases, including rheumatoid arthritis, asthma, inflammatory diseases, diabetes and digestive diseases. The purpose of this study was to provide a comprehensive review on the scientific reports that have been published about N. Sativa. The facts and statistics presented in this review article were gathered from the journals accessible in creditable databases such as Science Di
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Talekar, P. R. "Optimization of Nutritional and Sensory Properties of Oats, Makhana Dosa Premix." International Journal of Advance and Applied Research 11, no. 5 (2024): 165–70. https://doi.org/10.5281/zenodo.12241652.

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Healthy and Fiber & Iron rich products is gaining a lot of importance now a days incorporating it with healthy ingredients like Oats, Makhana, Palak, Kalonji, Chia seed, Flex seed, Black gram, Salt.etc. the combination of palak and oats , makhana Dosa Premix seems to be beneficial and also an attractive option . Study aims around production of a beneficial Dosa Premix made of healthy, ingredients like Oats, Makhana, Palak, Kalonji ,Chia seed , Flex seed ,Black gram , Salt .etc. beans combination can be a centre of attraction and make all age group attracted towards the formulated product .
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Arpitha, H. S., K. Umesha, and G. S. Anilkumar. "Influence of Elicitors on Growth and Yield of Black Cumin (Nigella sativa L.) Varieties." Asian Journal of Soil Science and Plant Nutrition 10, no. 2 (2024): 182–89. http://dx.doi.org/10.9734/ajsspn/2024/v10i2274.

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Black cumin is a miracle herb, an emerging seed spice and a medicinal plant of great demand. Black cumin has been used since thousands of years as a spice and food preservative as well as a protective and curative remedy for several disorders. A field experiment was conducted at the Department of Plantation, Spices, Medicinal and Aromatic Crops, College of Horticulture, UHS Campus, GKVK, Bengaluru, from November 2018 to March 2019. The experiment followed a randomized complete block design (RCBD) with three replications and included two factors: varieties and elicitors. Among the various treat
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S S Meena, Y K Sharma, R D Meena, et al. "Ajmer Nigella -20: A new high-yielding nigella variety." International Journal of Seed Spices 13, no. 1 and 2 (2024): 44–50. http://dx.doi.org/10.56093/ijss.v13i1-2.6.

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Nigella (Nigella sativa L.) well known as black cumin belongs to the Ranunculaceae family and is an important seed spice crop grown in India. The genus Nigella comprises more than 116 species, the most popular of which is Nigella sativa L. Nigella is classified as a seed spice because its dried seeds are used as a spice. ICAR-NRCSS, Ajmer has developed the Ajmer Nigella- 20 (AN-20) variety through the mass selection breeding method. This variety starts flowering in 85-90 days after seed sowing in the field and matures in 145-150 days. It belongs to the medium maturity group. Plants of AN-20 ar
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Alam, Mahboob, Shabir Ahmad Bhat, Shameem Ahmad Rather, et al. "A Comprehensive review of Nigella sativa (kalonji) from the Unani perspective." Journal of Drug Delivery and Therapeutics 13, no. 10 (2023): 121–28. http://dx.doi.org/10.22270/jddt.v13i10.6239.

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The remarkable therapeutic properties of Nigella sativa, often known as black seed or kalonji are well recognized. The use of N. sativa seeds and its oil has a long history in various traditional food and medical systems. As stated by the holy prophet of Islam (PBUH), Shoneez is important since it can cure all diseases with the exception of death. It is widely used in several conventional medical systems, including Unani Tibb, Chinese medicine, Ayurveda, and Siddha.
 The goal of the current review is to provide a thorough overview of the literature on scientific studies of the pharmacogno
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Cahyo, Septian Dwi, Ani Kurniawati, Didah Nur Faridah, and Munif Ghulamahdi. "Growth, Production and Bioactive Content of Several Black Cumin (Nigella sativa L.) Accessions With Different Harvesting Times in a D3 Type Climate Regime." Journal of Tropical Crop Science 7, no. 03 (2020): 104–12. http://dx.doi.org/10.29244/jtcs.7.03.104-112.

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 Black cumin (Nigella sativa L.) is a species Ranunculaceae family which grows in the Middle Eastern and Southern Mediterranean countries. Black cumin is also known as habbatus sauda , or kalonji in South Asia. Black cumin seeds are used as spice traditional medicine; the essential oil compound in the seeds has been identified as thymoquinone. Thymoquinone has a potent antioxidant effect, which could protect organs from oxidative damage by generating free radical agents. Indonesia is one of the most geographically diverse country in the world. Some regi
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Shital, Sagale* Rohit Jadhav Archana Chavan Dhananjay Khandebharad Komal Matsagar. "A Review on Formulation and Evaluation of Tetra herbal Hair Oil." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4186–94. https://doi.org/10.5281/zenodo.15511498.

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In today’s world, where everyone chooses instant effect mainly concern with health and cosmetic, but after a couple of days it gives major side effects that’s why major group of peoples turning towards Herbal products which gives more effect and less side effects. Today’s generation is facing for many health issues, also issues related to skin, hairs. So, the peoples from each generation whether men or women facing to hair problems like, Hair growth, spilt ends, hair baldness, Dandruff, Hair Loss, etc. These problems are due to Nutritional Deficiency, emotional & physical
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Habib, Nida, and Shahnaz Choudhry. "HPLC Quantification of Thymoquinone Extracted from Nigella sativa L. (Ranunculaceae) Seeds and Antibacterial Activity of Its Extracts against Bacillus Species." Evidence-Based Complementary and Alternative Medicine 2021 (April 20, 2021): 1–11. http://dx.doi.org/10.1155/2021/6645680.

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The medicinal importance of Nigella sativa seeds for treating various ailments is portrayed by its traditional uses. Owing to its immense pharmacological importance, the thymoquinone phytoconstituent of N. sativa can prove beneficial for the South Asian countries including Pakistan, where this seed is commonly produced and healthcare facilities are limited. In this study, the antibacterial activity of various extracts of N. sativa seeds, extracted thymoquinone, and oil samples have been investigated against Bacillus subtilis and Bacillus licheniformis using well and disc diffusion assay. The i
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Eid, Ahmad M., Nagib A. Elmarzugi, Laila M. Abu Ayyash, Maher N. Sawafta, and Hadeel I. Daana. "A Review on the Cosmeceutical and External Applications ofNigella sativa." Journal of Tropical Medicine 2017 (2017): 1–6. http://dx.doi.org/10.1155/2017/7092514.

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It is estimated by the World Health Organization (WHO) that most of the world’s population depends on herbal medicine for their health care.Nigella sativa (N. sativa),also known as black-caraway and as “Kalonji,” is a well-known seed all over the world. It is one of the most common medicinal plants worldwide and contains many useful chemical constituents that we can find in its fixed oil, such as thymoquinone, thymohydroquinone, dithymoquinone, thymol, nigellicine, carvacrol, nigellimine, nigellicine, nigellidine, and alpha-hederin. Due to these numerous important ingredients it was found that
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Thakur, Ankur, Komal Pathania, Lovish Sharma, and Deepika. "Exploring the Potential of Nigella Sativa Seeds: A Modern Perspective on an Ancient Remedy." Journal of Advances in Medicine and Medical Research 37, no. 1 (2025): 6–16. https://doi.org/10.9734/jammr/2025/v37i15691.

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Nigella sativa (N. Sativa) seeds are widely recognized for their medicinal properties, which make them valuable for both the culinary and pharmaceutical industries. The traditional plant that is most widely used is N. sativa and also known by other names like black cumin and kalonji. The N. Sativa is grown and distributed throughout India, primarily in the states of Punjab, Himachal Pradesh, Bihar, Bengal, and Assam, as well as in Bangladesh, Bangladesh, Syria, Lebanon, Israel, and South Europe. Numerous beneficial and bioactive chemical components, including thymoquinoline, thymoquinone, alph
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Kaje, Geeta Nandkishor* Thore Dinesh Dipak. "Study of Nigella Sativa on Diabetes Mellitus." International Journal of Pharmaceutical Sciences 3, no. 1 (2025): 1152–68. https://doi.org/10.5281/zenodo.14650784.

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Various studies have been conducted on the effect of medicinal plants in the treatment of different diseases, including diabetes. Nigella Sativa (N. sativa) is a plant with edible and medicinal properties that are of interest to scientists in traditional and complementary medicine, and much research has been conducted on this plant. Comprehensive reports are used to investigate the effect of N. sativa in vitro, animal models, and clinical trials in the treatment of diabetic diseases. An online database search was conducted to investigate the potential anti-diabetic effect of N. sativa. The res
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Gafoor, Abdul Gufran Abdul, Dr DT Bornare, and Dr SG Jaiswal. "Review on development of idli pre-mix by incorporation of black cumin seeds (Kalonji Seeds)." Journal of Current Research in Food Science 5, no. 1 (2024): 162–65. http://dx.doi.org/10.22271/foodsci.2024.v5.i1c.141.

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Agarwal, Yogesh Kumar, Ramchandra, Anubha Srivastav, Hemant Kumar, and Bijay Kumar Singh. "Correlation Studies on Different Growth Parameter of Spice Crops under Poplar Based Agroforestry System." International Journal of Environment and Climate Change 14, no. 1 (2024): 213–21. http://dx.doi.org/10.9734/ijecc/2024/v14i13827.

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The Present study was carried out to estimate the correlation of intercrop viz., Fennel, Ajowain, Coriander, Fenugreek, Mentha, Kalonji, Chilli and Cumin under Poplar-based agroforestry system. Experiment was conducted under 15 years old existing poplar based agri-silviculture system using Randomized Block Design (RBD) with three replications and 8 treatments in central part of state U.P. The treatments used under experimentation are (C1) Fennel, (C2) Ajowain, (C3) Coriander, (C4) Fenugreek, (C5) Mentha, (C6) Kalonji, (C7) Chilli, and (C8) Cumin. The significantly positive and negative correla
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Shrishti Joshi, Shrishti Joshi. "RECENT ADVANCEMENTS IN ADDRESSING THE NUTRITIONAL, INDUSTRIAL AND THERAPEUTIC EFFECTS OF MAGICAL SPICE: KALONJI (Nigella Sativa)"." International Journal of Seed Spices 14, no. 1 (2025): 16–24. https://doi.org/10.56093/ijss.v14i1.2.

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Nigella Sativa, also called black cumin or kalonji, is a highly valued and flexible plant that has been used in food, medicine, and industry for a long time. Because of their unique taste and smell, the seeds are very popular. They are used in everything from lamb meals to bread and chutneys. Nigella sativa is used in food, but it has also been looked at to see if it could be used as a drug. It's been used to treat health problems like hyperhomocysteinemia, heart disease, and high blood pressure because it kills bacteria and fights free radicals. This "magical spice" is also used in many diffe
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Jamir, Alemmoa R., Narayan Chattopadhyay, and Manisha Ch. Momin. "Effect of biofertilizers with various levels of inorganic nutrients on growth and yield of black cumin (Nigella sativa L.) var. Azad Kalonji." Environment Conservation Journal 22, no. 1&2 (2021): 73–78. http://dx.doi.org/10.36953/ecj.2021.221212.

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The objective of the study is to reduce the amount of inorganic fertilizers by using biofertilizers with the aim of sustainable agriculture. The field experiment was conducted at the HRS, Mondouri, BCKV, West Bengal, India during rabi season of 2019-20. The experiment consisted of 14 treatments replicated thrice, comprising of three levels inorganic fertilizers (50, 75 and 100%) of recommended NPK and three biofertilizers viz. Azospirillum lipoferum (N fixer), Bacillus megaterium (potash mobilizer) and Fraturia aurantia (K mobilizer) as soil application. The results indicated that the maximum
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Poojitha, Ravipati, Arpita Shrivastav, Neeraj Shrivastava, et al. "Inhibitory effect of spices on beta lactamase enzyme of resistant bacteria isolatedfrom milk of healthy cattle." Indian Journal of Dairy Science 76, no. 5 (2023): 466–72. http://dx.doi.org/10.33785/ijds.2023.v76i05.007.

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Present study was undertaken to observe the effect of spices on the extended Spectrum beta lactamase enzyme of ESBL Producing Enterobacteriaceae Group of Bacteria isolated from healthy cattle milk. Out of 100 samples collected randomly from various dairy farms located at the different areas of Rewa 14samples characterized by the phenotypic standard methods were found to be ESBL positive giving a prevalence rate of 14%.Inhibitory potential and per cent inhibition of beta lactamase enzyme were observed against dry powder of Methi seeds(Trigonella foenum-graecum), dry zinger, (Zingiberofficinale)
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Amin, F., N. Islam, Nfn Anila, and A. H. Gilani. "Clinical efficacy of the co-administration of Turmeric and Black seeds (Kalongi) in metabolic syndrome – A double blind randomized controlled trial – TAK-MetS trial." Complementary Therapies in Medicine 23, no. 2 (2015): 165–74. http://dx.doi.org/10.1016/j.ctim.2015.01.008.

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Abro, Shaukat Ali, Dhani Bux, Mumtaz Ali, et al. "Integrated Influence of Banana Pseudostem Scuture Waste Compost and Mineral Fertilizer on Growth and Yield of Chia (Salvia hispanica)." Plant Health 3, no. 1 (2024): 135–43. https://doi.org/10.33687/planthealth.03.01.5462.

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Integrated use of mineral fertilizers with organic sources like compost as a source of nutrients becomes more efficient in terms of boosting growth, increasing yield, and restoring soil fertility and soil health. A field experiment was initiated at the Medicinal Plants and Tobacco Research Institute (ARC) in Tandojam focusing on the cultivation of kalongi seed. The experiment was laid out in a Complete Randomized Block Design with six treatments with four replicates. The treatments were T1. Control T2, Compost+ 25% NPK, T3, Compost+ 50% NPK, T4, Compost+ 75% NPK and T6, Compost+ 100% NPK. The
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Fatima, Tooba, Reshma Jolly, Fariha Mushahid, et al. "Hydroxyapatite/Chondroitin Sulphate Nanocomposite Infused with Black Seed Oil for Bone Tissue Applications: Physicochemical Characterizations and In Vitro Screening." ChemistrySelect 9, no. 42 (2024). http://dx.doi.org/10.1002/slct.202404741.

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AbstractMorbidities associated with natural bone have highlighted the need of advanced bioactive implants for the replacement of damaged bone. Known for their beneficial bioactivity and biocompatibility, Nigella sativa seeds (kalonji/black seed) are traditionally used in many medications. This research focuses on the positive impact of black seed extract on the chondroitin sulfate‐based hydroxyapatite nanocomposite for bone tissue regeneration applications. Novel nanocomposites with varied concentrations of black seed extract (0, 1, 2, and 3 wt%) were fabricated through a coprecipitation appro
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Mahmudov, A. V., O. S. Abduraimov, Sh B. Erdonov, U. G. Gayibov, and L. Yu Izotova. "Bioecological features of Nigella sativa L. in different conditions of Uzbekistan." Plant Science Today, March 17, 2022. http://dx.doi.org/10.14719/pst.1510.

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The article is devoted to the study of bio-ecological features of black caraway (kalonji) in different conditions of introduction. The analysis of the periods of ontogenesis, the biology of flowering, fruiting (seed productivity) in different conditions of Uzbekistan was carried out. By results of phenological researches the differences of terms of phases of the vegetative period and its turn, by morphometric parameters are revealed. Emergence of buds in Nigella sativa under conditions of introduction is observed in the first decade of May, sometimes in the middle of May, depending on weather
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"Nigella sativa in Comparison to Steroids in Managing Oral Submucous Fibrosis." Pakistan Journal of Medicine and Dentistry, April 14, 2022. http://dx.doi.org/10.36283/pjmd11-2/008.

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Background: Nigella sativa (N. sativa), a natural herb, commonly known as Black seed or Kalonji, has a prolonged medicinal history of more than 2000 years. Oral submucous fibrosis (OSMF) is a chronic inflammatory disorder, which is mostly treated with steroids. This clinical trial was conducted to assess the effectiveness of N. sativa oil in comparison to steroids for treating OSMF. Methods: This randomized clinical trial consisted of n=39 clinically diagnosed OSMF patients aged 18 years and above. Patients were divided through randomization into two groups. Group 1 was prescribed steroid loti
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ASSI, Mohammed Abdulrazzaq, NOOR Mohd Hezmee MOHD, Noor Farhana BACHEK, et al. "The Various Effects of Nigella Sativa on Multiple Body Systems in Human and Animals." August 17, 2016. https://doi.org/10.5281/zenodo.3354290.

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Nigella sativa  (Black seeds) has been recognized as one of the most popular herbs in many  parts of the world for centuries. It was used in the world as folk medicine to cure different kinds of  diseases. This plant has been considered as one of the main sources of nutrition and healthcare for  humans as well as animals. It has been perceived as Kalonji; it is a southwest Asian plant that flowers  annually. The seeds and oil of this plant have been used in food; in addition, it has a long history in  the  making  of  medicines.  In  addit
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balasubramanian, Rajkapoor, Naina Mohamed Pakkir Maideen, Arun Shanmugam, and Harikrishnan Narayanaswamy. "A Review of Pre-Clinical Data on the Pharmacotherapeutic Potential of Black Seeds (Nigella sativa) against Influenza Virus Infection." Current Traditional Medicine 11 (April 29, 2025). https://doi.org/10.2174/0122150838352681250404051446.

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Background and Objective: Influenza is a respiratory virus, and certain patients with some chronic conditions and other risk factors are vulnerable to severe infection requiring hospitalizations and further fatal complications. Few antiviral drugs are approved for the management of patients with influenza infection. Since N. sativa supplementation significantly reduces all-cause mortality, improves viral clearance, and diminishes viral loads in patients with SARS-CoV-2 infection and other viruses, including hepatitis C virus, our review focuses on the antiviral efficacy of black seeds (N. sati
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AA, Mirza, Usmani H, Malik S, et al. "Effects of Active Compounds of Nigella sativa in COVID-19: A Narrative Review." Recent Advances in Anti-Infective Drug Discovery 18 (February 22, 2023). http://dx.doi.org/10.2174/2772434418666230222140805.

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Background: SARS-CoV-2 infection that led to the COVID-19 pandemic has changed human health and the economy globally. SARS CoV-2 is a type of Coronaviruses that has caused pneumonia and its complications with many deaths over the past two years. The use of hydroxychloroquine and chloroquine, accepted as generally safe for patients with autoimmune diseases or malaria, was attempted in many trials for COVID-19 treatment. Nigella sativa (NS) (black caraway, also known as black cumin, nigella or Kalonji) is an annual flowering plant of the Ranunculaceae family, chemically composed of the main cons
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Khatoon, Mariyam, Poonam Kushwaha, Shazia Usmani, and Kumud Madan. "Dermaceutical Utilization of Nigella sativa Seeds: Applications and Opportunities." Drug Research, November 28, 2023. http://dx.doi.org/10.1055/a-2196-1815.

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AbstractSkin diseases have recently become a major concern among people of all ages due to their highly visible symptoms and persistent and difficult treatment, which significantly impact their quality of life. Nigella sativa seeds, also known as "black seeds" or "kalonji," are one of the most commonly used herbal medicines due to their wide range of biological and pharmacological activities. It contains a wide range of bioactive constituents found in both fixed and essential oils. It has been used for hundreds of years as an alternative ethnomedicine to treat a wide range of skin conditions.
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"Green Tea and Nigella Sativa- Herbs in Non-Alcoholic Fatty Liver Disease." Journal of Sheikh Zayed Medical College 11, no. 4 (2021): 1–2. http://dx.doi.org/10.47883/jszmc.v11i04.160.

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Non alcoholic fatty liver disease (NAFLD) is foremost cause of progressive liver disorder worldwide. It has strong association with obesity 41-61%, metabolic syndrome 30-56%, Type-2 diabetes 18- 28%, dyslipidemia 52-83% and hypertension 15- 46%. These risk factors promote NAFLD as a global heath issue especially in western countries with a prevalence rate of about 20-30%. In recent years, the prevalence rate 15-30% has been found in Asian countries in general population due to strong influence of life style modification and urbanization pattern to the associated risk factors. There is an urgen
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