Littérature scientifique sur le sujet « Linee guida EULAR »

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Articles de revues sur le sujet "Linee guida EULAR"

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Maldonado, Ana Luisa P., and R. Jeremy Astley. "SwirlProp: A tool for sound propagation and attenuation in swirling flows." International Journal of Aeroacoustics 20, no. 5-7 (2021): 588–609. http://dx.doi.org/10.1177/1475472x211052591.

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The current trends for next generation turbofan engines are towards shorter nacelles and increased distances between the fan and the outlet guide vanes. This leads to an overall reduction in lined surface areas as well as an increase in the relative importance of the interstage liner, which is the liner placed between the rotor blades and the stator vanes. So far most of the efforts have been on liners for intakes and bypass ducts. The interstage is different in that the liner is subject to a mean flow with a strong swirl component and shear. The SwirlProp code was developed to contribute to u
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Kang, J. H., S. Ahamed, K. H. Sa, S. W. Han, and Y. M. Kang. "THU0077 CADHERINS GUIDE THE DIRECTIONAL MIGRATION OF THE SYNOVIOCYTES IN RHEUMATOID ARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 251.3–251. http://dx.doi.org/10.1136/annrheumdis-2020-eular.6426.

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Background:Aggressiveness of synoviocytes and collective migration of organized synovial tissues play a key role in the pathogenesis of pannus invasion into adjacent joint structure. Interactions among synovial cells for grouped movement, however, have not been properly elucidated.Objectives:We hypothesized that cadherins which have functions on the synovial invasion in RA, may play a critical role in collective migration of rheumatoid synoviocytes.Methods:Cadherins expression patterns on the synoviocytes isolated from patients with RA were evaluated using RT-PCR, flow cytometry, and western b
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Luz, Saturnino, and Masood Masoodian. "A comparison of linear and mosaic diagrams for set visualization." Information Visualization 18, no. 3 (2018): 297–310. http://dx.doi.org/10.1177/1473871618754343.

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Linear diagrams have been shown to compare favourably to better known forms of set visualization, such as Venn and Euler diagrams, in supporting non-interactive assessment of set relationships. Recent studies that compared several variants of linear diagrams have demonstrated that users perform best at tasks involving identification of intersections, disjointness and subsets when using a horizontally drawn linear diagram with thin lines representing sets and employing vertical lines as guide lines. The essential visual task the user needs to perform in order to interpret this kind of diagram i
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Bower, Hannah, Thomas Frisell, Daniela di Giuseppe, et al. "Are JAKis more effective among elderly patients with RA, smokers and those with higher cardiovascular risk? A comparative effectiveness study of b/tsDMARDs in Sweden." RMD Open 9, no. 4 (2023): e003648. http://dx.doi.org/10.1136/rmdopen-2023-003648.

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ObjectivesTo investigate whether the relative effectiveness of janus kinase inhibitors (JAKis) versus tumour necrosis factor inhibitors (TNFi) or other biological disease-modifying antirheumatic drugs in rheumatoid arthritis differ by the presence or absence of risk factors for cardiovascular (CV) disease, age, sex and smoking.MethodsThrough Swedish registers, we identified 13 493 individuals with 3166 JAKi, 5575 non-TNFi and 11 286 TNFi treatment initiations 2016–2022. All lines of therapy were included, with the majority in second line or higher. Treatment response was defined as the proport
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Rollefstad, S., E. Ikdahl, J. Sexton, et al. "OP0121 MANAGEMENT OF DYSLIPIDAEMIA AND HYPERTENSION IN PATIENTS WITH RHEUMATOID ARTHRITIS – DATA FROM 19 COUNTRIES." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 80.2–80. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4236.

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Background:The realisation that subjects with rheumatoid arthritis (RA) are at increased risk of cardiovascular disease (CVD) has led to a growing interest in risk factor control in such people, but whether this has influenced the management of dyslipidaemia and hypertension (HT) is uncertain. In subjects with coronary heart disease (CHD), audits of CVD risk factor control are regularly performed, which makes it possible to evaluate guideline implementation over time.1Updated surveys on CVD risk management in patients with RA are needed.Objectives:To describe differences in lipid and blood pre
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Maranini, B., E. Silvagni, V. Venturelli, A. Piovani, E. Zagnoni, and M. Govoni. "AB0223 ADHERENCE TO TREAT-TO-TARGET APPROACH IN A RHEUMATOID ARTHRITIS COHORT: RETROSPECTIVE ANALYSIS FROM 3 YEARS OF REAL-LIFE EXPERIENCE IN A REFRACTORY CLINIC." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1295.2–1296. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2829.

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BackgroundThe European Alliance of Associations for Rheumatology (EULAR) advocates a “treat-to-target” (T2T) strategy for rheumatoid arthritis (RA) management, consisting in adjusting therapy if target is not achieved at 6 months. However, patients with moderate disease activity (MDA) currently constitute the most common RA patient subset in clinical practice, possibly leading to refractory RA, defined as resistance to multiple drugs with different mechanisms of action and persistence of physical symptoms and/or high disease activity (HDA). Real-life studies examining the impact of switching/s
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Rodriguez-García, S. C., E. Toledano Martinez, M. J. García de Yébenes, L. Carmona, and I. González-Álvaro. "AB0120 IDENTIFYING CORE VARIABLES TO DEVELOP A SEVERITY INDEX IN RHEUMATOID ARTHRITIS: A NATIONWIDE DELPHI CONSENSUS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1089. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1821.

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Background:Early interventions during the “window of opportunity” have been shown to improve clinical outcomes in rheumatoid arthritis (RA). However, intensive treatment can induce toxicity so identifying patients most likely to benefit from it is of great importance. Hence, tools for guiding therapeutic decisions in early disease stages are needed.Objectives:To identify core variables to develop a RA severity index according to an expert panel.Methods:An expert panel was prompted to analyze relevant variables to define a “severity” construct, specified as “early severe disease”, able to class
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Larosa, M., A. Ariani, D. Camellino, et al. "AB0302 DISCONTINUATION RATE AND PREDICTORS OF JAKI DISCONTINUATION IN A REAL LIFE COHORT: RESULTS FROM A MULTICENTRIC ITALIAN STUDY ON 864 PATIENTS WITH RA." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1334–35. http://dx.doi.org/10.1136/annrheumdis-2023-eular.4554.

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BackgroundThe recent EULAR recommendations [1,2] suggest using JAK-inhibitors (JAKis) for treating RA patients. These drugs include both selective (upadactinib and filgotinib) and unselective (tofacitinib and baricitinib) JAKis.ObjectivesTo describe JAKis’ discontinuation rate and to determine predictors of JAKIs’ discontinuation in a real life setting.MethodsAll patients with RA treated with JAKis were prospectively followed up for at least 12 months in this multicentric study carried out on 23 Italian centres. For each patient, the following variables were collected: sex, age, disease durati
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Telegin, A. I. "Formalism of Writing Out of Manipulators Dynamic Equation." Bulletin of the South Ural State University. Ser. Computer Technologies, Automatic Control & Radioelectronics 21, no. 4 (2021): 52–68. http://dx.doi.org/10.14529/ctcr210405.

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The problem of cumbersome equations of dynamics for manipulation systems of industrial robots (manipulators) with translational and rotational joints is solved. A new formalism for writing out the equations of dynamics of manipulators by using of guide cosines is proposed. Examples of writing out equations of dynamics of manipulators with guid cosines are given. The equations of dynamics in relative angles of rotation of bodies are obtained with the help of these guide cosines by applying their properties. These manipulators have from three to six degrees of freedom. In their equations of dyna
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Thèses sur le sujet "Linee guida EULAR"

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ZANETTI, ANNA. "The management of patients with rheumatoid arthritis: an overview of obstacles and improvement strategies." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2022. http://hdl.handle.net/10281/365542.

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L’artirite reumatoide (AR) è la più diffusa patologia autoimmune in Italia con elevati costi terapeutici e previdenziali associati. Questa patologia colpisce circa lo 0.5-1% della popolazione adulta, prevalentemente di genere femminile. Essendo una patologia degenerativa, i cui danni sono frequentemente irreversibili, una diagnosi precoce così come un adeguato trattamento ed un elevato livello di compliance del paziente allo stesso, potrebbero rallentare il peggioramento della malattia. Inoltre sono poco noti i possibili effetti della malattia e del suo trattamento sulle gravidanze e i success
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Actes de conférences sur le sujet "Linee guida EULAR"

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Pa´scoa, J. C., A. C. Mendes, and L. M. C. Gato. "Redesigning Annular Turbine Blade Rows Using a Viscous-Inviscid Inverse Design Method." In ASME Turbo Expo 2008: Power for Land, Sea, and Air. ASMEDC, 2008. http://dx.doi.org/10.1115/gt2008-50313.

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This paper presents the results of the aerodynamic redesign of an annular turbine blade row. The inverse method herein applied is an extension to 3D of an iterative inverse design method based on the imposition of the blade load, thickness distribution and stacking line. We define a mass-averaged mean tangential velocity over one blade pitch, ru¯θ, as the main design variable, since its derivative is related to the aerodynamic load. A time-lagged formulation for the 3D camber surface generator is given in order to include the blade thickness distribution into the design algorithm. The hybrid v
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Gastaldi, Chiara, and Muzio M. Gola. "Platform Centered Reduction: A Process Capturing the Essentials for Blade-Damper Coupled Optimization." In ASME Turbo Expo 2020: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/gt2020-16317.

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Abstract The purpose of this document is to continue along the line of research of the authors in the direction of developing an attractive tool for designers in the initial design phase of the damping of the turbomachinery blades. In particular, in order to guide their initial choice of a dry friction underplatform damper in the most appropriate way. The paper shows how, to this purpose, certain reasonable simplifications are introduced in the procedure and in the model, leaving the customary full high fidelity computations to the final design verification analysis. The key simplifications he
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Fredrick, Nicholas, and Milt Davis. "Investigation of the Effects of Inlet Swirl on Compressor Performance and Operability Using a Modified Parallel Compressor Model." In ASME 2011 Turbo Expo: Turbine Technical Conference and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/gt2011-45553.

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Serpentine ducts used by both military and commercial aircraft can generate significant flow angularity and total pressure distortion at the engine face. Most low by-pass ratio turbofan engines with mixed exhaust are equipped with inlet guide vanes (IGV) which can reduce the effect of moderate inlet distortion. High by-pass ratio and some low by-pass ratio turbofan engines are not equipped with IGVs, and swirl can in effect change the angle of attack of the fan blades. Swirl and total pressure distortion at the engine inlet will impact engine performance, operability, and durability. The impac
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