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Articles de revues sur le sujet « Lingual antimicrobial peptide »

Auteur : Grafiati

Publié le 7 juin 2025

Mis à jour le 2 août 2025

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1

Das, Hemen, Shahaj Uddin Ahmed, Dimpal Thakuria, et al. "Lingual Antimicrobial Peptide Expresses in Buffalo Mammary Gland." Animal Biotechnology 20, no. 2 (2009): 75–79. http://dx.doi.org/10.1080/10495390902786983.

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Isobe, N., J. Nakamura, H. Nakano, and Y. Yoshimura. "Existence of functional lingual antimicrobial peptide in bovine milk." Journal of Dairy Science 92, no. 6 (2009): 2691–95. http://dx.doi.org/10.3168/jds.2008-1940.

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Mitchell, Gordon B., Muthafar H. Al-Haddawi, Mary Ellen Clark, Jennifer D. Beveridge, and Jeff L. Caswell. "Effect of Corticosteroids and Neuropeptides on the Expression of Defensins in Bovine Tracheal Epithelial Cells." Infection and Immunity 75, no. 3 (2006): 1325–34. http://dx.doi.org/10.1128/iai.00686-06.

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ABSTRACT Susceptibility to bacterial pneumonia in cattle is enhanced by stressors such as transportation, weaning, and commingling, which trigger a physiologic stress response resulting in elevated levels of endogenous corticosteroids and catecholamines. To determine the effect of neuroendocrine mediators on the expression of innate defense peptides in the lung, bovine tracheal epithelial cells were exposed to dexamethasone, catecholamines, acetylcholine, or substance P, and then β-defensin expression was quantified using real-time reverse transcription-PCR. Basal expression of tracheal antimi

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4

Kalita, Dhruba Jyoti, Ashok Kumar, and Satish Kumar. "Structure-function studies of Bubalus bubalis lingual antimicrobial peptide analogs." Veterinary Research Communications 33, no. 2 (2008): 149–61. http://dx.doi.org/10.1007/s11259-008-9081-7.

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5

ISOBE, Naoki, Kenji HOSODA, and Yukinori YOSHIMURA. "Immunolocalization of lingual antimicrobial peptide (LAP) in the bovine mammary gland." Animal Science Journal 80, no. 4 (2009): 446–50. http://dx.doi.org/10.1111/j.1740-0929.2009.00652.x.

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Kalita, Dhruba Jyoti, and Ashok Kumar. "Molecular cloning and characterization of lingual antimicrobial peptide cDNA of Bubalus bubalis." Research in Veterinary Science 86, no. 1 (2009): 91–97. http://dx.doi.org/10.1016/j.rvsc.2008.05.002.

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Swanson, Kara, Stas Gorodetsky, Laura Good та ін. "Expression of a β-Defensin mRNA, Lingual Antimicrobial Peptide, in Bovine Mammary Epithelial Tissue Is Induced by Mastitis". Infection and Immunity 72, № 12 (2004): 7311–14. http://dx.doi.org/10.1128/iai.72.12.7311-7314.2004.

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ABSTRACT The expression of a β-defensin, the lingual antimicrobial peptide (LAP), in response to mastitis was investigated by real-time PCR of RNA from mastitic and control udder quarters. There was a positive relationship between somatic cell count in milk and LAP expression. In situ hybridization showed that LAP mRNA was expressed in epithelial cells of mastitic tissue. These results suggest that LAP plays a role in the innate immune response to mastitis.

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Isobe, Naoki, Toshihisa Sugino, Kohzo Taniguchi, Naoko Moriya, Kenji Hosoda, and Yukinori Yoshimura. "Differential localization of lingual antimicrobial peptide in the digestive tract mucosal epithelium of calves." Veterinary Immunology and Immunopathology 142, no. 1-2 (2011): 87–94. http://dx.doi.org/10.1016/j.vetimm.2011.03.020.

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Huang, Ya Qiong, Kazuhide Morimoto, Kenji Hosoda, Yukinori Yoshimura, and Naoki Isobe. "Differential immunolocalization between lingual antimicrobial peptide and lactoferrin in mammary gland of dairy cows." Veterinary Immunology and Immunopathology 145, no. 1-2 (2012): 499–504. http://dx.doi.org/10.1016/j.vetimm.2011.10.017.

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del Villar Pérez, Víctor Manuel, Alberto Barreras Serrano, Lourdes Carolina Pujol Manríquez, Luis Tinoco Gracia, Tonatiuh Melgarejo, and Alma Rossana Tamayo Sosa. "Expression of b-defensins LAP (lingual antimicrobial peptide) and TAP (antimicrobial peptide tracheal), and Psoriasin (S100A7), in bovine mammary gland with chronic mastitis by Staphylococcus aureus." Acta Universitaria 26, no. 4 (2016): 29–35. http://dx.doi.org/10.15174/au.2016.930.

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Yang, Jun, Yongming Sang, Kieran G. Meade, and Chris Ross. "The role of oct-1 in the regulation of tracheal antimicrobial peptide (TAP) and lingual antimicrobial peptide (LAP) expression in bovine mammary epithelial cells." Immunogenetics 63, no. 11 (2011): 715–25. http://dx.doi.org/10.1007/s00251-011-0547-3.

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Isobe, N., K. Morimoto, J. Nakamura, A. Yamasaki, and Y. Yoshimura. "Intramammary challenge of lipopolysaccharide stimulates secretion of lingual antimicrobial peptide into milk of dairy cows." Journal of Dairy Science 92, no. 12 (2009): 6046–51. http://dx.doi.org/10.3168/jds.2009-2594.

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Fales-Williams, A. J., K. A. Brogden, E. Huffman, J. M. Gallup, and M. R. Ackermann. "Cellular Distribution of Anionic Antimicrobial Peptide in Normal Lung and during Acute Pulmonary Inflammation." Veterinary Pathology 39, no. 6 (2002): 706–11. http://dx.doi.org/10.1354/vp.39-6-706.

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Anionic peptides (APs) are small antimicrobial peptides present in human and ovine lung. In this study APs were also detected in bovine lung, and production of APs in lungs with acute inflammation induced by various stimuli was determined. The distribution and intensity of APs were determined by immunohistochemistry in lungs of 1) neonatal calves (1-3 days of age) inoculated with Mannheimia (Pasteurella) haemolytica, a known inducer of the bovine β-defensin lingual antimicrobial peptide (LAP) or pyrogen-free saline (PFS), and 2) growing calves (3 months of age) similarly inoculated with M. hae

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Kawai, Kazuhiro, Hirohisa Akamatsu, Tetsu Obayashi, et al. "Relationship between concentration of lingual antimicrobial peptide and somatic cell count in milk of dairy cows." Veterinary Immunology and Immunopathology 153, no. 3-4 (2013): 298–301. http://dx.doi.org/10.1016/j.vetimm.2013.03.002.

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15

Abhishek, Mishra Asha Yadav Shardhanjali Behera. "Antimicrobial peptides from domestic & farm animals and its uses in veterinary medicine." Vet Farm Frontier 02, no. 04 (2025): 40–43. https://doi.org/10.5281/zenodo.15362986.

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Antimicrobial peptides (AMPs) are naturally occurring substances vital to the innate immune response against various pathogens. Over 4000 AMPs have been identified, with around 3000 sequences cataloged in databases, predominantly derived from animals and plants. They exhibit broad-spectrum antimicrobial activity, classified based on their source, composition, and activity, including antibacterial, antifungal, antiviral, antiparasitic, and antitumor properties. AMPs can be synthesized either constitutively or in response to pathogens, interacting with microbial membranes to compr

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Huang, Ya Qiong, Naoki Isobe, Yukinori Yoshimura, and Kenji Hosoda. "Immunolocalization and Correlation Frequencies of Lingual Antimicrobial Peptide and Lactoferrin in Bovine Alveolar Epithelium and Bovine Mammary Gland." Advanced Materials Research 781-784 (September 2013): 699–708. http://dx.doi.org/10.4028/www.scientific.net/amr.781-784.699.

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Mastitis is most critical disease in dairy cows and causes huge cost in the dairy industry. To prevent and treat it, it is important to understand the mechanisms of immune function in the mammary gland. Innate immunity is non-specific acute-response immune function. Some components of innate immunity in the mammary gland are found, e.g. Lingual Antimicrobial Peptide (LAP), Lactoferrin (LF). These components are found to be localized in the alveolar epithelium of mammary gland. LAP belongs to the β-defensin family, and plays a crucial role in killing a large variety of microorganisms. LF belong

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17

Isobe, Naoki, Ayumi Shibata, Hirokazu Kubota, and Yukinori Yoshimura. "Lingual antimicrobial peptide and lactoferrin concentrations and lactoperoxidase activity in bovine colostrum are associated with subsequent somatic cell count." Animal Science Journal 84, no. 11 (2013): 751–56. http://dx.doi.org/10.1111/asj.12113.

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Kawai, Kazuhiro, Kiyoshi Korematsu, Kiyoshi Akiyama, Miki Okita, Yukinori Yoshimura, and Naoki Isobe. "Dynamics of lingual antimicrobial peptide, lactoferrin concentrations and lactoperoxidase activity in the milk of cows treated for clinical mastitis." Animal Science Journal 86, no. 2 (2014): 153–58. http://dx.doi.org/10.1111/asj.12269.

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19

Souza, R. F. S., L. Rault, N. Seyffert, V. Azevedo, Y. Le Loir, and S. Even. "Lactobacillus casei BL23 modulates the innate immune response in Staphylococcus aureus-stimulated bovine mammary epithelial cells." Beneficial Microbes 9, no. 6 (2018): 985–95. http://dx.doi.org/10.3920/bm2018.0010.

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Probiotics have been adopted to treat and prevent various diseases in humans and animals. They were notably shown to be a promising alternative to prevent mastitis in dairy cattle. This inflammation of the mammary gland is generally of infectious origin and generates extensive economic losses worldwide. In a previous study, we found that Lactobacillus casei BL23 was able to inhibit the internalisation of Staphylococcus aureus, one of the major pathogens involved in mastitis, into bovine mammary epithelial cells (bMEC). In this study, we further explored the capacity of this strain to modulate

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20

Yamasaki, Ayumi, Yukinori Yoshimura, and Naoki Isobe. "Changes in the concentrations of somatic cell counts, lingual antimicrobial peptide and lactoperoxidase activity in milk at periovulatory period in dairy cows." Animal Science Journal 88, no. 3 (2016): 484–88. http://dx.doi.org/10.1111/asj.12644.

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Günther, Juliane, Shuzhen Liu, Kathrin Esch, Hans-Joachim Schuberth та Hans-Martin Seyfert. "Stimulated expression of TNF-α and IL-8, but not of lingual antimicrobial peptide reflects the concentration of pathogens contacting bovine mammary epithelial cells". Veterinary Immunology and Immunopathology 135, № 1-2 (2010): 152–57. http://dx.doi.org/10.1016/j.vetimm.2009.11.004.

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Liu, Shuzhen, Xuanming Shi, Isabel Bauer, Juliane Günther та Hans-Martin Seyfert. "Lingual antimicrobial peptide and IL-8 expression are oppositely regulated by the antagonistic effects of NF-κB p65 and C/EBPβ in mammary epithelial cells". Molecular Immunology 48, № 6-7 (2011): 895–908. http://dx.doi.org/10.1016/j.molimm.2010.12.018.

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23

Kalita, D. J., S. Sarma, and A. Baruah. "Molecular characterization of lingual antimicrobial peptide gene of local cattle (Bos indicus) of Assam and insilco designing of antimicrobial peptides." Indian Journal of Animal Research, of (August 16, 2018). http://dx.doi.org/10.18805/ijar.b-3299.

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Mammalian defensin is the one of the important antimicrobial peptides expressed by different epithelial lining of the living organisms. Present study was undertaken to characterize the lingual antimicrobial peptide (LAP) gene of Assam local cattle (Bos indicus ) for insilco designing of peptide for synthesis of novel antimicrobial agents. RNA was isolated from the tongue epithelial of Bos indicus and reverse transcribed with specific primer. The amplified PCR product was purified, cloned and sequenced. The size of the PCR product was 230 bp and cloned cDNA after sequencing revealed the open re

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24

Ackerman, Mark R., Kim A. Brogden, and P. B. McCray. "Antimicrobial Peptides and Surfactant Proteins." American Association of Bovine Practitioners Conference Proceedings, September 26, 2002, 159–65. http://dx.doi.org/10.21423/aabppro20025026.

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Although some vaccines and antibiotics have been very effective in preventing and treating respiratory disease, they have not been fully satisfactory. Recently, components of the innate immune system have been increasingly appreciated for their role in host defense against microbial pathogens. These molecules include lysozyme and lactoferrin, but recent work in cattle, sheep, man and other species have identified new classes of peptides expressed by respiratory epithelial cells that have potent microcidal activity in nanogram quantities. These peptides, termed antimicrobial peptides (AMP), inc

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SULTANA, REZINA, D. J. KALITA, S. SARMA, A. BARUAH, and B. DEVI. "Characterization of a novel antimicrobial peptide gene from the reproductive tract of indigenous cows (Bos indicus) of Asom." Indian Journal of Animal Sciences 86, no. 2 (2016). http://dx.doi.org/10.56093/ijans.v86i2.55778.

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Antimicrobial peptides are innate immune defense peptides protecting against infection. Defensins and cathelicidins are the two major antimicrobial peptides in eukaryotes. In the present study, female reproductive tract was collected from apparently healthy local cows (Bos indicus) of Asom after slaughter. cDNA was synthesized from the extracted RNA by reverse transcription and amplified the Lingual Antimicrobial Peptide (LAP) gene (227 bp) using specific primers. The purified product was sequenced and sequence were aligned Nucleotide sequence was BLAST with twelve published sequences and anal

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26

More, Dhanya. "Molecular characterization of Lingual antimicrobial peptide in the female reproductive tract of Buffalo." Veterinary World, 2011, 120. http://dx.doi.org/10.5455/vetworld.2011.120-123.

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Maiti, Pulak Kumar, and Sukhendu Mandal. "Comprehensive genome analysis of Lentzea reveals repertoire of polymer-degrading enzymes and bioactive compounds with clinical relevance." Scientific Reports 12, no. 1 (2022). http://dx.doi.org/10.1038/s41598-022-12427-7.

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AbstractThe genus Lentzea is a rare group of actinobacteria having potential for the exploration of bioactive compounds. Despite its proven ability to produce compounds with medical relevance, Lentzea genome analysis remains unexplored. Here we show a detailed understanding of the genetic features, biosynthetic gene clusters (BGCs), and genetic clusters for carbohydrate-active enzymes present in the Lentzea genome. Our analysis determines the genes for core proteins, non-ribosomal peptide synthetase condensation domain, and polyketide synthases-ketide synthase domain. The antiSMASH-based seque

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Larzábal, Mariano, Wanderson Marques Da Silva, Anmol Multani, et al. "Early immune innate hallmarks and microbiome changes across the gut during Escherichia coli O157: H7 infection in cattle." Scientific Reports 10, no. 1 (2020). http://dx.doi.org/10.1038/s41598-020-78752-x.

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AbstractThe zoonotic enterohemorrhagic Escherichia coli (EHEC) O157: H7 bacterium causes diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome (HUS) in humans. Cattle are primary reservoirs and EHEC O157: H7; the bacteria predominately inhabit the colon and recto-anal junctions (RAJ). The early innate immune reactions in the infected gut are critical in the pathogenesis of EHEC O157: H7. In this study, calves orally inoculated with EHEC O157: H7 showed infiltration of neutrophils in the lamina propria of ileum and RAJ at 7 and 14 days post-infection. Infected calves had altered mucin la

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López-Cano, Adrià, Marc Martínez-Miguel, Judith Guasch, Imma Ratera, Anna Arís, and Elena Garcia-Fruitós. "Exploring the impact of the recombinant Escherichia coli strain on defensins antimicrobial activity: BL21 versus Origami strain." Microbial Cell Factories 21, no. 1 (2022). http://dx.doi.org/10.1186/s12934-022-01803-7.

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AbstractThe growing emergence of microorganisms resistant to antibiotics has prompted the development of alternative antimicrobial therapies. Among them, the antimicrobial peptides produced by innate immunity, which are also known as host defense peptides (HDPs), hold great potential. They have been shown to exert activity against both Gram-positive and Gram-negative bacteria, including those resistant to antibiotics. These HDPs are classified into three categories: defensins, cathelicidins, and histatins. Traditionally, HDPs have been chemically synthesized, but this strategy often limits the

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Oyamada, Youki, Ei'ichi Iizasa, Amane Usa, and Konosuke Otomaru. "1,25‐Dihydroxyvitamin D₃ potentiates the innate immune response of peripheral blood mononuclear cells from Japanese Black cattle." Animal Science Journal 94, no. 1 (2023). http://dx.doi.org/10.1111/asj.13906.

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Abstract1,25‐Dihydroxyvitamin D3 (1,25(OH)2D3), a bioactive vitamin D, is known to regulate immune responses in mammals. However, its impact on the innate immune responses of Japanese Black cattle, which are beef cattle endemic to Japan, remains unknown. Thus, in this study, we investigated the effect of 1,25(OH)2D3 on the immune responses of peripheral blood mononuclear cells from Japanese Black cattle. As a result, the treatment of 1,25(OH)2D3 upregulated the expression of antibacterial peptides, bovine beta‐defensin 10 (DEFB10), and lingual antimicrobial peptide (LAP), in the presence and a

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Suzuki, Naoki, Rika Harada, Yusaku Tsugami, Takahiro Nii, and Naoki Isobe. "Concentrations of antimicrobial components in milk at dry off and postpartum and their relationships to new high somatic cell counts at quarter level in dairy cows." Journal of Dairy Research, February 16, 2024, 1–3. http://dx.doi.org/10.1017/s0022029924000050.

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Abstract We investigated the antimicrobial components in cow milk at dry off and postpartum and their contribution in preventing new high SCC at quarter level. Milk samples from 72 quarters of 19 lactating cows were collected at last milking before dry off and at 7 d after parturition. Milk yield of each cow was recorded and SCC, IgG, IgA, lactoferrin, lingual antimicrobial peptide (LAP), and S100A7 concentrations in each quarter milk sample were measured. The postpartum milk yield was significantly higher than that at dry off. The IgG, IgA and lactoferrin concentrations in milk at dry off wer

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Jaisue, Jirapat, Jinkun Sun, Nur Laili Marufah, Masashi Itagaki, and Naoki Isobe. "Changes in Antimicrobial Component Concentrations at the Onset of the Dry Period and Peripartum in Dairy Cows." Animal Science Journal 96, no. 1 (2025). https://doi.org/10.1111/asj.70085.

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ABSTRACTWe aimed to clarify antimicrobial component (AMC) dynamics during the dry period in dairy cows and determine the impacts of varying somatic cell count (SCC) at the onset of the dry period on the subsequent changes in AMC concentrations in milk. Milk samples obtained from Holstein dairy cows were categorized into low‐SCC and high‐SCC groups. AMC concentrations in milk were measured at four time points: (1) Onset of the dry period, (2) before calving, (3) immediately after calving, and (4) 1 week postpartum. In the low‐SCC group, SCC and lingual antimicrobial peptide increased prepartum

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Jin, Di, Guangjun Chang, Kai Zhang, Junfei Guo, Tianle Xu, and Xiangzhen Shen. "Rumen-derived lipopolysaccharide enhances the expression of lingual antimicrobial peptide in mammary glands of dairy cows fed a high-concentrate diet." BMC Veterinary Research 12, no. 1 (2016). http://dx.doi.org/10.1186/s12917-016-0755-z.

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Brand, Kathrin Susanne, Viviane Filor, and Wolfgang Bäumer. "Early inflammatory events of mastitis—a pilot study with the isolated perfused bovine udder." BMC Veterinary Research 17, no. 1 (2021). http://dx.doi.org/10.1186/s12917-021-03029-y.

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Abstract Background Bovine mastitis is an important health and cost factor in the milk industry. To elucidate whether isolated perfused bovine udders can be used to study early inflammatory events of mastitis, 1 mg of lipopolysaccharide (LPS) was instilled into quarters of 10 isolated perfused bovine udders. Three hours and 6 h after LPS instillation, tissue samples were taken from the gland cistern and base of the udder, subsequently stored in RNAlater and processed for the determination of inflammation-dependent gene regulation by real-time RT-qPCR. Gene expression analysis was performed usi

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