Articles de revues : « Lokal infiltrations anestesi »

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Abenavoli, Fabio Massimo, et Roberto Corelli. « About Local Anesthesia Infiltration ». Annals of Plastic Surgery 50, n^o 6 (juin 2003) : 666–67. http://dx.doi.org/10.1097/01.sap.0000069067.53530.ab.

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Podoshin, Ludwig, Rita Gerstel, Moshe Goldsher, Milo Fradis, Sonia Vaida, Shelton Malatskey et Luis Gaitini. « Effects of Peritonsillar Infiltration on Post-Tonsillectomy Pain ». Annals of Otology, Rhinology & ; Laryngology 105, n^o 11 (novembre 1996) : 868–70. http://dx.doi.org/10.1177/000348949610501105.

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The concept that local infiltration of the operative area with a local anesthetic when using general anesthesia could alleviate postoperative pain is well known. We tested this concept on 129 patients scheduled for elective tonsillectomy. The patients were investigated in a double-blind, randomized study, and the operation was carried out via the standard technique of infiltrating the peritonsillar area preoperatively. The results indicated that preincisional infiltration of the tonsils with bupivacaine hydrochloride markedly decreased the intensity of pain following tonsillectomy, well beyond the immediate postoperative period.

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Fadinie, Wulan, Dadik Wahyu Wijaya et Hasanul Arifin. « Perbandingan Efek Analgesi Infiltrasi Morfin 10 Mg dan Bupivakain 0,5% 2 Mg/KgBB pada Seksio Sesarea dengan Teknik Anestesi Spinal ». Jurnal Anestesi Obstetri Indonesia 3, n^o 2 (17 septembre 2020) : 73–9. http://dx.doi.org/10.47507/obstetri.v3i2.45.

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Latar Belakang: Persalinan dengan seksio sesarea sangat umum dilakukan dan setiap intervensi yang dapat mengurangi rasa sakit pasca operasi layak diteliti lebih lanjut. Cara terbaik untuk mengurangi rasa sakit dengan memberikan analgesi yang langsung bekerja pada area luka. Telah diketahui morfin memiliki reseptor perifer sehingga pemberian secara subkutan dapat menjadi metode yang sangat efektif dalam manajemen nyeri pasca operasiTujuan: Membandingkan efek analgesi dari infiltrasi lokal morfin 10 mg dengan bupivakain 2mg/kgBB 0,5% pada pasca seksio sesarea dengan anestesi spinal. Subjek dan Metode: Penelitian ini adalah uji klinis acak tersamar ganda dengan 100 sampel wanita hamil, usia 20-40 tahun, PS-ASA I-II yang akan menjalani seksio sesarea elektif dan darurat dengan anestesi spinal. Setelah dihitung secara statistik, sampel dibagi secara acak menjadi 2 kelompok. Kelompok pertama mendapat morfin 10 mg dan kelompok kedua mendapat bupivakain 0,5% 2 mg/kgBB secara infiltrasi lokal subkutan didaerah luka operasi. Skala nyeri dinilai dengan VAS. Hasilnya diuji dengan uji T-independent, Chi-Square, dengan nilai signifikan 95% (p <0,05%, signifikan secara statistik). Hasil: Pada kelompok morfin pemberian analgesi tambahan lebih sedikit daripada kelompok bupivakain, hasilnya berbeda bermakna secara statistik (p <0.05) pada setiap jam pengamatan. Efek samping tidak ditemukan pada kedua kelompok. Kelompok morfin meringankan rasa sakit lebih baik daripada kelompok bupivakain dengan skor VAS yang lebih rendah pada setiap jam pengamatanSimpulan: Infiltrasi lokal subkutan 10 mg morfin memberikan efek analgetik yang lebih baik pada pasien pasca seksio sesarea dengan anestesi spinal dibandingkan dengan bupivacain 0,5% 2 mg/kgBB, tanpa efek samping. Comparison of the Analgesic Effects of 10 mg Morphine and 2mg/BW Bupivacaine 0.5% Infiltration in Cesarean Section with Spinal Anesthesia Technique Abstract Background: Nowadays, deliveries by cesarean section are more commonly done, any intervention that can make progression to reduce post-operative pain are feasible for further study. The best way to reduce pain is by administration pain relieve drug that directly act in wound. It is known that morphine has peripheral receptors, so subcutaneous administration can be a very effective method of postoperative pain management. Objective: To compare analgetic effect from local infiltration of 10 mg morphine with 2mg/BW bupivacaine 0.5% in post cesarean section with spinal anesthesiaSubject and Methods: This study was done by double blinded randomized clinical trial with 100 samples of pregnant women, age 20-40 years, PS-ASA I-II that will undergo elective and emergency cesarean section with spinal anesthesia. After calculated statistically, all samples divided randomly into 2 groups. First group got morphine 10 mg and second group got bupivacaine 0.5% 2 mg/BW infiltration at the area of surgical wound. Pain scale was evaluated by VAS. The result was tested by T-independent test, Chi-Square, with significant value 95% (p<0.05%, statistically significant). Result: In morphine group, the additional analgesia was less than bupivacaine group, the results were statistically significant (p <0.05) at each hour of observation. No side effects were found in either group. The morphine group relieved pain better than the bupivacaine group with lower VAS scores at each hour of observation.Conclusion: Infiltration of 10 mg morphine subcutaneous compared to bupivacaine 0.5% 2mg/BW give better analgetic effect in post cesarean section patients with spinal anesthesia, without any side effects

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Yildiran, Gokce, Osman Akdag, Mehtap Karamese et Zekeriya Tosun. « Local infiltration anesthesia in tenolysis surgery ». Hand and Microsurgery 6, n^o 2 (2017) : 1. http://dx.doi.org/10.5455/handmicrosurg.233919.

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Vishnevsky, А. А. « Local infiltration anesthesia by the creeping infiltrate method ». Kazan medical journal 26, n^o 5-6 (24 décembre 2020) : 569–77. http://dx.doi.org/10.17816/kazmj52489.

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In modern surgery, there are a large number of different types of general anesthesia and local anesthesia. This most clearly indicates that there is still no such method of pain relief that could be completely satisfied.

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Asyari, Ade, Novialdi Novialdi, Elniza Morina, Rimelda Aquinas, Nasman Puar et Hafni Bachtiar. « The effect of local ketamine infiltration on post tonsillectomy pain scale ». Oto Rhino Laryngologica Indonesiana 50, n^o 1 (1 juillet 2020) : 38. http://dx.doi.org/10.32637/orli.v50i1.351.

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Background: Post tonsillectomy pain is one of the surgery side effects that most disturbing for patient’s comfort and will cause dysphagia, low intake, dehydration, secondary infection and bleeding. Ketamine is an anesthetic drug that has strong analgesic effect and easily available in any hospital at relatively cheap price. Objective: To find out the effect of local ketamine infiltration on the post tonsillectomy pain scale. Method: An experimental study during tonsillectomy with a Post Test Control Group on 12 samples without local infiltration of ketamine and 12 samples with local infiltration of ketamine in peritonsillar pillar. The pain was assessed 2 hours and 24 hours post extubation with pain Visual Analog Scale (VAS). Result: The VAS value from patients who were given local infiltration of ketamine in peritonsillar pillar were lower (5.83 ± 0.72 at 2 hours and 2.83 ± 0.58 at 24 hours post extubation) compared to patients without ketamine infiltration (7.83 ± 0.58 at 2 hours and 3.58 ± 0.51 at 24 hours post extubation). The result showed statistically significant difference (p <0.05) at 2 hours and 24 hours post extubation. Conclusion: The VAS score of the ketamine infiltration group is lower at 2 hours and 24 hours post extubation than the group without ketamine infiltration, showing there was a noticeable effect of local ketamine infiltration on the post tonsillectomy pain scale.Keywords : post tonsillectomy pain, ketamine, local infiltration, visual analog scale ABSTRAKLatar belakang: Nyeri pascatonsilektomi adalah salah satu efek samping operasi yang sangat mengganggu kenyamanan pasien, dan dapat menyebabkan gangguan menelan, kurangnya asupan nutrisi, dehidrasi, infeksi sekunder dan perdarahan. Ketamin merupakan obat anestesi yang memiliki efek analgetik yang kuat dan mudah didapatkan di semua tipe rumah sakit dengan harga yang relatif murah. Tujuan: Mengetahui efek pemberian infiltrasi lokal ketamin terhadap skala nyeri pascatonsilektomi. Metode: Penelitian eksperimental dengan desain Post Test Control Group pada 12 sampel tanpa pemberian infiltrasi lokal ketamin dan 12 sampel dengan pemberian infiltrasi lokal ketamin di pilar peritonsil saat tonsilektomi. Dilakukan penilaian nyeri 2 jam dan 24 jam pascaekstubasi menggunakan skala nyeri Visual Analog Scale (VAS). Hasil: Nilai VAS pasien yang diberi infiltrasi lokal ketamin di pilar peritonsil lebih rendah (5,83±0,72 pada 2 jam dan 2,83 ± 0,58 pada 24 jam pascaekstubasi) dibanding tanpa diberi infiltrasi lokal ketamine (7,83 ± 0,58 pada 2 jam dan 3,58± 0,51 pada 24 jam pascaekstubasi), dan bermakna secara statistik (p<0,05) pada kedua penilaian. Kesimpulan: Terdapat efek nyata infiltrasi lokal ketamin terhadap skala nyeri pascatonsilektomi, dimana nilai VAS kelompok yang diberi infiltrasi ketamin lebih rendah, baik pada 2 jam ataupun 24 jam pascaekstubasi dibanding kelompok yang tidak diberi infiltrasi ketamin.

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TARASOV, D. A., A. V. LYCHAGIN, V. A. KOZHEVNIKOV, G. G. ZAKHAROV, YA A. RUKIN et I. N. TARABARKO. « LOCAL INFILTRATION ANESTHESIA AFTER TOTAL KNEE ARTHROPLASTY ». Department Of Traumatology And Orthopedics 2 (octobre 2018) : 74–79. http://dx.doi.org/10.17238/issn2226-2016.2018.2.74-79.

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Yoshida, Kenji, Eri Tanaka, Hiroyoshi Kawaai et Shinya Yamazaki. « Effect of Injection Pressure of Infiltration Anesthesia to the Jawbone ». Anesthesia Progress 63, n^o 3 (1 septembre 2016) : 131–38. http://dx.doi.org/10.2344/15-00024.1.

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To obtain effective infiltration anesthesia in the jawbone, high concentrations of local anesthetic are needed. However, to reduce pain experienced by patients during local anesthetic administration, low-pressure injection is recommended for subperiosteal infiltration anesthesia. Currently, there are no studies regarding the effect of injection pressure on infiltration anesthesia, and a standard injection pressure has not been clearly determined. Hence, the effect of injection pressure of subperiosteal infiltration anesthesia on local anesthetic infiltration to the jawbone was considered by directly measuring lidocaine concentration in the jawbone. Japanese white male rabbits were used as test animals. After inducing general anesthesia with oxygen and sevoflurane, cannulation to the femoral artery was performed and arterial pressure was continuously recorded. Subperiosteal infiltration anesthesia was performed by injecting 0.5 mL of 2% lidocaine containing 1/80,000 adrenaline, and injection pressure was monitored by a pressure transducer for 40 seconds. After specified time intervals (10, 20, 30, 40, 50, and 60 minutes), jawbone and blood samples were collected, and the concentration of lidocaine at each time interval was measured. The mean injection pressure was divided into 4 groups (100 ± 50 mm Hg, 200 ± 50 mm Hg, 300 ± 50 mm Hg, and 400 ± 50 mm Hg), and comparison statistical analysis between these 4 groups was performed. No significant change in blood pressure during infiltration anesthesia was observed in any of the 4 groups. Lidocaine concentration in the blood and jawbone were highest 10 minutes after the infiltration anesthesia in all 4 groups and decreased thereafter. Lidocaine concentration in the jawbone increased as injection pressure increased, while serum lidocaine concentration was significantly lower. This suggests that when injection pressure of subperiosteal infiltration anesthesia is low, infiltration of local anesthetic to the jawbone may be reduced, while transfer to oral mucosa and blood may be increased.

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AJIMI, Junko, Junichi NISHIYAMA et Toshiyasu SUZUKI. « A Questionnaire Survey on Local Infiltration Anesthesia during Epidural Anesthesia ». JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA 33, n^o 3 (2013) : 436–39. http://dx.doi.org/10.2199/jjsca.33.436.

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Ram, D., E. Amir, R. Keren, J. Shapira et E. Davidovich. « Mandibular Block or Maxillary Infiltration ». Journal of Clinical Pediatric Dentistry 36, n^o 3 (1 avril 2012) : 245–50. http://dx.doi.org/10.17796/jcpd.36.3.n2x8m38866487020.

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Purpose: Local anesthesia by mandibular block or maxillary infiltration is commonly administered to children receiving dental treatment of primary molars. Discomfort, when presenting, most often involves the lower lip. The purpose of this study was to investigate whether children would be more opposed to attending a dental treatment following anesthesia by mandibular block than by maxillary infiltration. Methods: Each of 102 children in two age groups: 3 to 5 years, and 6 to 9 years, received the two types of local anesthesia at dental appointments one week apart. Their opposition to attending a subsequent appointment was assessed by parent report. Results: More adverse reactions were observed during and following anesthesia with mandibular block than with maxillary infiltration. Few of the children in either age group expressed opposition to attend a dental visit after receiving mandibular block or maxillary infiltration in the previous visit. Conclusions: Though more adverse reactions were observed in children following mandibular block than maxillary infiltration, this did not result in increased opposition to attend a subsequent dental appointment.

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Adams, Wendy, et Stephen J. Morgan. « Diplopia following sub-Tenonʼs infiltration of local anesthesia ». Journal of Cataract & ; Refractive Surgery 28, n^o 9 (septembre 2002) : 1694–97. http://dx.doi.org/10.1016/s0886-3350(01)01280-9.

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Liu, Liehua, Shiming Cheng, Rui Lu et Qiang Zhou. « Extrapedicular Infiltration Anesthesia as an Improved Method of Local Anesthesia for Unipedicular Percutaneous Vertebroplasty or Percutaneous Kyphoplasty ». BioMed Research International 2016 (2016) : 1–4. http://dx.doi.org/10.1155/2016/5086414.

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Aim.This report introduces extrapedicular infiltration anesthesia as an improved method of local anesthesia for unipedicular percutaneous vertebroplasty or percutaneous kyphoplasty.Method.From March 2015 to March 2016, 44 patients (11 males and 33 females) with osteoporotic vertebral compression fractures with a mean age of71.4±8.8years (range: 60 to 89) received percutaneous vertebroplasty or percutaneous kyphoplasty. 24 patients were managed with conventional local infiltration anesthesia (CLIA) and 20 patients with both CLIA and extrapedicular infiltration anesthesia (EPIA). Patients evaluated intraoperative pain by means of the visual analogue score and were monitored during the procedure for additional sedative analgesia needs and for adverse nerve root effects.Results.VAS of CLIA + EPIA and CLIA group was2.5±0.7and4.3±1.0,respectively, and there was significant difference (P=0.001). In CLIA group, 1 patient required additional sedative analgesia, but in CLIA + EPIA group, no patients required that. In the two groups, no adverse nerve root effects were noted.Summary.Extrapedicular infiltration anesthesia provided good local anesthetic effects without significant complications. This method deserves further consideration for use in unipedicular percutaneous vertebroplasty and percutaneous kyphoplasty.

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Popov, Sergei V., Igor N. Orlov, Vladimir M. Obidnyak, Sergey M. Malevich, Maxim V. Borichev, Stanislav M. Basok, Nariman K. Gadzhiev et al. « The role of local anesthesia to reduce pain after PСNL ». Pediatrician (St. Petersburg) 7, n^o 4 (15 décembre 2016) : 113–18. http://dx.doi.org/10.17816/ped74113-118.

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The goal of the study was to assess the level of postoperative pain in patients undergoing PCNL after paratubal infiltration with local anesthetic to compare this method of anesthesia with a control group where local anesthesia was not provided. 63 patients were included with kidney stones, confirmed by computer tomography (CT), who were planned to undergo percutaneous nephrolithitomy (PСNL). During the observation 6 patients have been excluded in accordance with the exclusion criteria. The remaining 57 patients were randomized into 2 groups: group A (n= 28) at the end of the operation received paratubal infiltration of 0.5% sol. ropivacaine; group B (n= 29) (controls) — local anesthesia was not used. Postoperative pain was assessed by means of VAS-score 1 hour, 6 hours and 24 hours after surgery. Systemic analgesia was performed with NSAIDs (intramuscular injection of 100 mg ketoprofen) when requested by the patient (Patient-Controlled Analgesia). In patients with local anesthesia, the total VAS score evaluated after 1 and 6 hours after the operation was significantly lower than in the control group. The average amount of ketoprofen required for postoperative analgesia in the group of patients with paratubal infiltration was significantly lower than in the control group. Paratubal infiltration of local anesthetic after PCNL significantly reduced postoperative pain and tended to reduce the amount of NSAIDs to eliminate pain, which in turn may reduce the risk of complications associated with NSAID.

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Satoh, Kenichi, Ayako Ohashi, Miho Kumagai, Hideki Hoshi, Kousei Otaka et Shigeharu Joh. « Severe Bradycardia Possibly due to a Local Anesthetic Oral Mucosal Injection during General Anesthesia ». Case Reports in Dentistry 2015 (2015) : 1–3. http://dx.doi.org/10.1155/2015/896196.

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Local anesthesia may induce systemic complications leading to parasympathetic activity leading to bradycardia and hypotension. We report a case of a 50-year-old man undergoing dental surgery under general anesthesia who experienced severe bradycardia and hypotension after local anesthesia infiltration. Concerns regarding the utilization of a relatively large lumen injection needle for local anesthesia during general anesthesia are discussed.

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Mittal, M., A. Kumar, D. Srivastava, P. Sharma et S. Sharma. « Pain Perception : Computerized versus Traditional Local Anesthesia in Pediatric Patients ». Journal of Clinical Pediatric Dentistry 39, n^o 5 (1 septembre 2015) : 470–74. http://dx.doi.org/10.17796/1053-4628-39.5.470.

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Background: Local anesthetic injection is one of the most anxiety- provoking procedure for both children and adult patients in dentistry. A computerized system for slow delivery of local anesthetic has been developed as a possible solution to reduce the pain related to the local anesthetic injection. Study design: The present study was conducted to evaluate and compare pain perception rates in pediatric patients with computerized system and traditional methods, both objectively and subjectively. Study design: It was a randomized controlled study in one hundred children aged 8-12 years in healthy physical and mental state, assessed as being cooperative, requiring extraction of maxillary primary molars. Children were divided into two groups by random sampling - Group A received buccal and palatal infiltration injection using Wand, while Group B received buccal and palatal infiltration using traditional syringe. Visual Analog scale (VAS) was used for subjective evaluation of pain perception by patient. Sound, Eye, Motor (SEM) scale was used as an objective method where sound, eye and motor reactions of patient were observed and heart rate measurement using pulse oximeter was used as the physiological parameter for objective evaluation. Results: Patients experienced significantly less pain of injection with the computerized method during palatal infiltration, while less pain was not statistically significant during buccal infiltration. Heart rate increased during both buccal and palatal infiltration in traditional and computerized local anesthesia, but difference between traditional and computerized method was not statistically significant. Conclusion: It was concluded that pain perception was significantly more during traditional palatal infiltration injection as compared to computerized palatal infiltration, while there was no difference in pain perception during buccal infiltration in both the groups

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Arapostathis, Konstantinos Nikolaos, Nikolaos Nestoras Dabarakis, Trilby Coolidge, Anastasios Tsirlis et Nikolaos Kotsanos. « Comparison of Acceptance, Preference, and Efficacy Between Jet Injection INJEX and Local Infiltration Anesthesia in 6 to 11 Year Old Dental Patients ». Anesthesia Progress 57, n^o 1 (1 mars 2010) : 3–12. http://dx.doi.org/10.2344/0003-3006-57.1.3.

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Abstract Needleless devices have been developed to provide anesthesia without injections. Little controlled research has examined the acceptability of needleless devices in pediatric patients. The aims of the study were to compare children’s acceptance and preference for one type of needleless jet injection with classical local infiltration as well as to evaluate the efficacy of the needleless anesthesia. Eighty-seven nonfearful children with no previous experience of dental anesthesia were studied using a split-mouth design. The first dental procedure was performed with the classical infiltration anesthesia. The same amount of anesthetic was administered using the INJEX needleless device in a second session 1 week later, during which a second dental procedure was performed. Patients rated their acceptance and preference for the 2 methods, and the dentist recorded data about the need for additional anesthesia. More negative experiences were reported for the INJEX method. Most (73.6%) of the children preferred the traditional method. Among the 87 treatment procedures attempted following the use of INJEX, 80.5% required additional anesthesia, compared with 2.3% of those attempted following traditional infiltration. Traditional infiltration was more effective, acceptable, and preferred, compared with the needleless INJEX.

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Mohamed, Ahmed Abdalla, Tamer Fayez Safan, Hamed Fathy Hamed et Maged Abdelwahab Abdelaziz Elgendy. « Tumescent Local Infiltration Anesthesia for Mini Abdominoplasty with Liposuction ». Open Access Macedonian Journal of Medical Sciences 6, n^o 11 (19 novembre 2018) : 2073–78. http://dx.doi.org/10.3889/oamjms.2018.475.

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AIM: To evaluate the feasibility and safety of mini abdominoplasty with liposuction under local tumescent anaesthesia (LA) as the sole anaesthetic modality. METHODS: The study included 60 female patients with a mean age of 33.3 ± 5.6 years. Local infiltration using a mixture of 1:1000 epinephrine (1 ml), 2% lidocaine (100 ml) and 0.5% Levobupivacaine (50 ml) in 2500 ml saline was started with Local infiltration started with the abdomen, outer thigh, hips, back, inner thighs and knees. After Mini Abdominoplasty with supplemental liposuction was conducted and application of suction drains wound closure was performed, and the tight bandage was applied. Pain during injection, incision and surgical manipulations was determined. Duration of postoperative analgesia, till oral intake and return home, patients and surgeon satisfaction scores were determined. RESULTS: All surgeries were conducted completely without conversion to general anaesthesia. Injection pain was mild in 46 patients, moderate in 10 and hardly tolerated in 4 patients. Incision pain was mild in 16 patients, while 44 patients reported no sensation. During the surgical procedure, 6 patients required an additional dose of LA. Meantime till resumption of oral intake was 1.6 ± 0.9 hours. Meantime till home return was 5.6 ± 2.4 hours. Twelve patients were highly satisfied, 18 patients were satisfied, and these 42 patients were willing to repeat the trial if required. Eight patients found the trial is good and only one patient refused to repeat the trial and was dissatisfied, for a mean total satisfaction score of 3.1 ± 0.9. CONCLUSION: Mini Abdominoplasty with liposuction could be conducted safely under tumescent LA with mostly pain-free intraoperative and PO courses and allowed such surgical procedure to be managed as an office procedure. The applied anaesthetic procedure provided patients’ satisfaction with varying degrees in about 97% of studied patients.

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Chen, Yong, Zhansong Zhou, Wei Sun, Tao Zhao et Hong Wang. « Minimally invasive percutaneous nephrolithotomy under peritubal local infiltration anesthesia ». World Journal of Urology 29, n^o 6 (22 juillet 2011) : 773–77. http://dx.doi.org/10.1007/s00345-011-0730-z.

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Xu, Tiantong, Rong Tian, Pan Qiao, Zhihua Han, Qingfeng Shen et Yutao Jia. « Application of continuous epidural anesthesia in transforaminal lumbar endoscopic surgery : a prospective randomized controlled trial ». Journal of International Medical Research 47, n^o 3 (11 janvier 2019) : 1146–53. http://dx.doi.org/10.1177/0300060518817218.

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Objective This study aimed to compare intraoperative lower back pain and leg pain, surgical time, and intraoperative X-ray dose in patients offered local infiltration anesthesia or continuous epidural anesthesia for transforaminal endoscopic spine system (TESSYS) surgery. Methods A total of 98 patients who received TESSYS treatment for single-segmental lumbar disc herniation were included, and were randomly divided into two groups: group A (49 cases; local infiltration anesthesia) and group B (49 cases; continuous epidural anesthesia). Surgical duration, intraoperative X-ray dose, and visual analog scale (VAS) scores of lower back pain and leg pain before surgery, during surgery, and 48 h after surgery were recorded and compared. Results After surgery, the VAS scores of both lower back pain and leg pain decreased in group A, and similar findings were found in group B. Group B had a shorter surgical duration, lower intraoperative X-ray dose, and lower intraoperative VAS scores of lower back pain and leg pain compared with group A. Conclusion Compared with local infiltration anesthesia, continuous epidural anesthesia was more effective for pain relief during TESSYS for single-segmental lumbar disc herniation, and also contributed to a shorter surgical duration and lower X-ray exposure.

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Rehman, Nurain, et Samir Riaz Qazi. « Efficacy of Topical Benzocaine in Maxilla : A Randomized Controlled Trial ». Anesthesia Progress 66, n^o 1 (1 mars 2019) : 24–29. http://dx.doi.org/10.2344/anpr-66-01-01.

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This study aims to compare the effect of topical anesthesia against the use of no topical agent on pain of needle penetration and local anesthesia deposition during buccal infiltration in anterior maxilla. In a randomized controlled trial, 100 adult participants were randomly allocated to the benzocaine group (received 20% benzocaine gel) and no benzocaine group (received no topical agent) prior to buccal infiltration in maxillary anterior teeth. A 27-gauge needle was used to deposit 2% lidocaine with 1:100,000 epinephrine. Pain of needle penetration and local anesthesia deposition was recorded separately using an 11-point Numeric Pain Rating Scale. Results showed that although 20% benzocaine significantly reduced pain on needle penetration during buccal infiltration in maxillary anterior teeth, the difference was small and the clinical significance is not clear. Topical anesthetic did not affect pain of local anesthetic deposition.

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Novikov, Andrei, Ekaterina Blinova, Elena Semeleva, Karina Karakhanjan, Mikhail Mironov, Dmirty Blinov, Yuliya Krainova, Dmitry Pakhomov, Olga Vasilkina et Elena Samishina. « On local anesthetic action of some dimethylacetamide compounds ». Research Results in Pharmacology 4, n^o 4 (2 décembre 2018) : 1–8. http://dx.doi.org/10.3897/rrpharmacology.4.31440.

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The study aim was to explore local anesthetic properties of some tertiary and quaternary derivatives of dimethylacetamide. Materials and methods. The study was performed on white laboratory mice and rats of both sexes, male Agouti guinea pigs, and isolated sciatic nerves of lake frog. In the focus of the study there were two quaternary and eight tertiary compounds of dimethylacetamide with substituted anion with some amino and carbonic acids residue. A local anesthetic property was predicted by computational analysis. Acute toxicity of the most promising substances was studied in mice through subcutaneous route. Local anesthetic activity of tertiary compounds LKhT-3-00, LKhT-4-00 and quaternary LKhT-12-02 was studied on models of terminal, infiltration and conduction anesthesia. The influence of substances on mixed nerve conduction was investigated on lake frog’s isolated sciatic nerves. Results and discussion. The greatest probability of the local anesthetic activity during computational analysis was estimated for the tertiary derivatives of dimethylacetamide LKhT-3-00 and LKhT-4-00 and for the quaternary compound LKhT-12-02. According to their toxicological profile, the compounds belong to moderately toxic substances (class 3). On the model of terminal and infiltration anesthesia, substances LKhT-3-00 and LKhT-4-00 at concentrations of 0.5-1% rapidly cause deep and prolonged anesthesia. On the models of conduction anesthesia, the quaternary derivative of dimethylacetamide LKhT-12-02 has the greatest analgesic effect. The duration of the effect of the substance is over 3 hours. All the investigated compounds block sciatic nerve conduction. The longest effect is registered for LKhT-12-02. Conclusions. Dimethylacetamide derivatives at concentrations of 0.5-1.0% exhibit a local anesthetic activity, and are effective for terminal, conduction and infiltration anesthesia. Their effect is due to blockade of nerve conduction.

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ŞERMET ELBAY, Ülkü, Mesut ELBAY, Can KAYA, Ceren UĞURLUEL et Canan BAYDEMİR. « The Efficacy of DentalVibe Injection Comfort System Producing Vibration Impuls to Reduce Injection Pain of Palatal Local Infiltration Anesthesia in Children ». Turkiye Klinikleri Journal of Dental Sciences 21, n^o 3 (2015) : 207–15. http://dx.doi.org/10.5336/dentalsci.2015-44348.

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Beiranvand, Siavash, et Mahmoud Moradkhani. « Bupivacaine Versus Liposomal Bupivacaine For Pain Control ». Drug Research 68, n^o 07 (6 novembre 2017) : 365–69. http://dx.doi.org/10.1055/s-0043-121142.

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AbstractLocal infiltrations and regional blocks have been some of the effective ways employed to manage and control post-operative pain. One of the limitations of administration of local anesthesia drugs in post-operative conditions is its inability to act for a longer period of time. Multi-vesicular liposomes made up of bupivacaine have been progressively used for their increased duration of action. Compared to bupivacaine HCL, local infiltration of liposomal bupivacaine have shown to have a significantly increase the duration and delay in peak plasma concentration. In this article, we attempt to compare liposomal bupivacaine and bupivacaine based on available clinical literatures. Liposomal bupivacaine has been demonstrated to have promising implications in post- operative pain control resulting in increased patient satisfaction; reduced hospital admission and opioid induced adverse events. Clinical studies have identified liposomal bupivacaine to be effective in delivering increased post-operative pain control. The purpose of this review is to give a comprehensive comparison between bupivacaine liposomal and conventional bupivacaine based on reported clinical trials.

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Ruzibaev, Dilmurod, Timur Minasov et Hamdam Karimov. « Experience with intraoperative infiltration anesthesia during knee replacement ». Vrač skoroj pomoŝi (Emergency Doctor), n^o 5 (1 avril 2020) : 76–81. http://dx.doi.org/10.33920/med-02-2005-10.

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Intraoperative local infiltration anesthesia significantly reduces the need for opioid anesthesia in the postoperative period, accelerates early activation and rehabilitation due to adequate analgesia, and reduces postoperative blood loss due to vascular spasm in the wound during total knee replacement. Due to the quick adaptation of patients to the joint implant, it is possible to reduce the time spent by patients in hospitals, as well as reduce the cost of treatment.

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Isik, Kubilay, Abdullah Kalayci et Ercan Durmus. « Comparison of Depth of Anesthesia in Different Parts of Maxilla When Only Buccal Anesthesia Was Done for Maxillary Teeth Extraction ». International Journal of Dentistry 2011 (2011) : 1–3. http://dx.doi.org/10.1155/2011/575874.

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Objective. Recently, some authors reported that maxillary teeth could be extracted without using palatal anesthesia, but they did not clearly specify the extracted teeth. This is important, because apparently the local anesthetic solution infiltrates the maxilla and achieves a sufficient anesthesia in the palatal side. Thus, thickness of the bone may affect the depth of anesthesia. The aim of this study was to compare the depth of anesthesia in different parts of the maxilla when only a buccal infiltration anesthesia was done.Patients and Method. The maxilla was divided into anterior, premolar, and molar regions. In each region, 15 teeth were extracted with a single buccal infiltration. The patient marked the pain level on a numerical rating scale.Results. Anesthesia depth was sufficient and was not significantly different () among three maxillary regions.Conclusion. Except for surgical interventions, all maxillary teeth can be extracted using only a buccal infiltration anesthesia.

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Fowler, Sara, Melissa Drum, Al Reader, John Nusstein et Mike Beck. « Pulpal Anesthesia of Adjacent Teeth Following Infiltration of 2% Lidocaine With 1:100,000 Epinephrine in the Maxillary Lateral Incisor and First Molar ». Anesthesia Progress 66, n^o 1 (1 mars 2019) : 14–19. http://dx.doi.org/10.2344/anpr-65-04-03.

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The purpose of this study was to determine anesthetic success in adjacent teeth following a primary infiltration of the maxillary lateral incisor and first molar using 1.8 mL of 2% lidocaine with 1:100,000 epinephrine. Three hundred eight asymptomatic subjects received an infiltration of a cartridge of 2% lidocaine with 1:100,000 epinephrine over the maxillary lateral incisor (163 subjects) or first molar (145 subjects). Pulpal anesthesia of the injected tooth and adjacent mesial and distal teeth was monitored with the electric pulp tester in 2-minute cycles for a total of 60 minutes. No response from the subject at the maximum output (80 reading) of the pulp tester was used as the criterion for pulpal anesthesia. Comparisons of the odds of pulpal anesthesia (defined as an 80/80 response to electric pulp testing over 60 minutes) between the experimentally injected tooth and adjacent teeth were analyzed using mixed-models, repeated-measures logistic regression. When compared with the lateral incisor infiltration, the adjacent mesial tooth (central incisor) and distal tooth (canine) achieved statistically lower anesthetic success. When compared with the first molar, the mesial tooth (second premolar) did not differ statistically. However, significant differences were shown between the first molar and the second molar, with the distal tooth (second molar) achieving a statistically higher rate of pulpal anesthesia, which was related to a better duration of anesthesia. For asymptomatic patients, local anesthesia of the adjacent mesial (central incisor) and distal (canine) teeth to the infiltrated lateral incisor had lower pulpal anesthetic success. Because standard infiltration anesthesia of the lateral incisor is of short duration, repeating the infiltration at 30 minutes will result in a high incidence of pulpal anesthesia for 60 minutes. Local anesthesia of the adjacent distal tooth to the first molar (second molar) had a statistically higher rate of total pulpal anesthesia than the infiltrated first molar due to the longer duration of pulpal anesthesia. However, if pulpal anesthesia is required for 60 minutes in the first and second molars, the clinician may need to add an additional infiltration to ensure anesthesia.

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Townsend, Janice A., Steven Ganzberg et S. Thikkurissy. « The Effect of Local Anesthetic on Quality of Recovery Characteristics Following Dental Rehabilitation Under General Anesthesia in Children ». Anesthesia Progress 56, n^o 4 (1 décembre 2009) : 115–22. http://dx.doi.org/10.2344/0003-3006-56.4.115.

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Abstract This study is a randomized, prospective, double-blind study to evaluate the effects of the combination of local anesthetics and an intravenous nonsteroidal anti-inflammatory drug (NSAID) vs NSAID alone on quality of recovery following dental rehabilitation under general anesthesia (GA). Twenty-seven healthy children aged 3–5.5 years underwent dental rehabilitation under GA. Fifteen children in the experimental group received oral infiltration of local anesthetic in addition to intravenous ketorolac tromethamine, while 12 children in the control group received intravenous ketorolac tromethamine alone for postoperative pain management. Pain behaviors were evaluated immediately postoperatively using a FLACC scale and 4 hours postoperatively by self-report using various scales. Parents reported perception of child pain and comfort and any occurrences of postoperative cheek biting. The use of intraoral infiltration local anesthesia for complete dental rehabilitation under general anesthesia for children aged 3–5.5 years did not result in improved pain behaviors in the postanesthesia care unit (PACU), nor did it result in improved pain behaviors 4–6 hours postoperatively as measured by the FLACC scale, FACES scale, and subjective reports of parents or a PACU nurse. Those children receiving local anesthesia had a higher incidence of negative symptoms related to local anesthetic administration, including a higher incidence of lip and cheek biting, which was of clinical importance, but not statistically significant. Infiltration of local anesthetic for dental rehabilitation under general anesthesia did not improve quality of recovery in children aged 3–5.5 years.

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Filippiadis, Dimitrios K. « CT-Guided Percutaneous Infiltration for the Treatment of Alcock’s Neuralgia ». Pain Physician 3;14, n^o 2;3 (14 mars 2011) : 211–15. http://dx.doi.org/10.36076/ppj.2011/14/211.

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The pudendal nerve may be strained either between the sacrospinous and sacrotuberous ligaments at the ischial spine level or within Alcock’s canal. Alcock’s neuralgia is a rare, painful condition caused by compression of the pudendal nerve within Alcock’s canal (pudendal canal) which is an aponeurotic tunnel that cannot be stretched. Patients usually present with intense, unilateral pain involving anatomic areas along the pudendal nerve’s root, genital, anal, and pelvic regions causing mobility impairment. A computed tomography (CT) - guided percutaneous infiltration of the pudendal nerve with a mixture of a local anesthetic and a long-acting corticosteroid is a safe and efficient method that reduces the pain caused by the neuralgia. Corticosteroids and local anesthetics interfere with the neurons, the encoding, and the processing of noxious stimuli; interrupt the pain-spasm cycle; and reduce inflammation. The injected glucocorticosteroid may take 3-5 days to reach its anti-inflammatory effect; therefore, the initial pain relief from the local anesthetic is followed by a baseline pain return and then secondary pain relief at 3-5 days. The procedure is performed under minimal or no anesthesia. In general, at discharge, a responsible person must accompany the patient and ensure a safe return home. Clinical evaluation is performed after 7-10 days. There are 2 types of potential complications that are associated with percutaneous steroid infiltrations: intra-operative (associated with needle placement) and post-operative (infection, bleeding and those associated with the injectate administration). In all cases that steroids were administered within therapeutic doses, no complications were noted. In conclusion, CT-guided percutaneous infiltration with a mixture of long-acting corticosteroid and local anesthetic seems to be a safe and efficient method for the treatment of Alcock’s neuralgia. Key words: Alcock’s canal, neuralgia, corticosteroid, pudendal; nerve, local anesthetic, computed tomography, infiltration, percutaneous, image guided.

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Noguchi, K. « Anal Surgery in an Outpatient Clinic under Local Infiltration Anesthesia. » Nippon Daicho Komonbyo Gakkai Zasshi 48, n^o 10 (1995) : 1100–1106. http://dx.doi.org/10.3862/jcoloproctology.48.10_1100.

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Smith, Forrest L., Richard W. Davis et Richard Carter. « Influence of Voltage-sensitive Ca++Channel Drugs on Bupivacaine Infiltration Anesthesia in Mice ». Anesthesiology 95, n^o 5 (1 novembre 2001) : 1189–97. http://dx.doi.org/10.1097/00000542-200111000-00024.

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Background Local anesthesia has been traditionally associated with blockade of voltage-sensitive sodium (Na(+)) channels. Yet in vitro evidence indicates that local anesthetic mechanisms are more complex than previously understood. For example, local anesthetics bind and allosterically modify 1,4-dihydropyridine-sensitive Ca(++) channels and can reduce Ca(++) influx in tissues. The current study examines the influence of voltage-sensitive Ca(++) channels in bupivacaine infiltration anesthesia. Methods Baseline tail-flick latencies to radiant heat nociception were obtained before subcutaneous infiltration of bupivacaine and Ca(++)-modulating drugs in the tails of mice. No musculature is contained in the tail that could result in motor block. The magnitude of infiltration anesthesia over time, as well as the potency of bupivacaine alone or in the presence of Ca(++)-modulating drug, was assessed by obtaining test latencies. Results The 1,4-dihydropyridine L-type Ca(++) channel agonist S(-)-BayK-8644 reduced the duration of action and potency of bupivacaine anesthesia. In opposite fashion, nifedipine and nicardipine increased the effects of bupivacaine. Neither nifedipine nor nicardipine alone elicited anesthesia. Alternatively, the phenylalkylamine L-type blocker verapamil elicited concentration-dependent anesthesia. Other Ca(++) channel subtype blockers were investigated as well. The N-, T-, P-, and Q-type channel blockers, omega-conotoxin GVIA, flunarizine, omega-agatoxin IVA, and omega-conotoxin MVIIC, respectively, were unable to modify bupivacaine anesthesia. Conclusions These results indicate that heat nociception stimulates Ca(++) influx through L-type channels on nociceptors in skin. Although other voltage-sensitive Ca(++) channels may be located on skin nociceptors, only the L-type channel drugs affected bupivacaine in the radiant heat test.

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Bai, Johnny Wei, Dong An, Anahi Perlas et Vincent Chan. « Adjuncts to local anesthetic wound infiltration for postoperative analgesia : a systematic review ». Regional Anesthesia & ; Pain Medicine 45, n^o 8 (30 mai 2020) : 645–55. http://dx.doi.org/10.1136/rapm-2020-101593.

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Local anesthetics (LAs) are commonly infiltrated into surgical wounds for postsurgical analgesia. While many adjuncts to LA agents have been studied, it is unclear which adjuncts are most effective for co-infiltration to improve and prolong analgesia. We performed a systematic review on adjuncts (excluding epinephrine) to local infiltrative anesthesia to determine their analgesic efficacy and opioid-sparing properties. Multiple databases were searched up to December 2019 for randomized controlled trials (RCTs) and two reviewers independently performed title/abstract screening and full-text review. Inclusion criteria were (1) adult surgical patients and (2) adjunct and LA agents infiltration into the surgical wound or subcutaneous tissue for postoperative analgesia. To focus on wound infiltration, studies on intra-articular, peri-tonsillar, or fascial plane infiltration were excluded. The primary outcome was reduction in postoperative opioid requirement. Secondary outcomes were time-to-first analgesic use, postoperative pain score, and any reported adverse effects. We screened 6670 citations, reviewed 126 full-text articles, and included 89 RCTs. Adjuncts included opioids, non-steroidal anti-inflammatory drugs, steroids, alpha-2 agonists, ketamine, magnesium, neosaxitoxin, and methylene blue. Alpha-2 agonists have the most evidence to support their use as adjuncts to LA infiltration. Fentanyl, ketorolac, dexamethasone, magnesium and several other agents show potential as adjuncts but require more evidence. Most studies support the safety of these agents. Our findings suggest benefits of several adjuncts to local infiltrative anesthesia for postoperative analgesia. Further well-powered RCTs are needed to compare various infiltration regimens and agents.Protocol registrationPROSPERO (CRD42018103851) (https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=103851)

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Park, Shin Ae, Inhyung Lee, Y. Lyon Lee, Man Bok Jeong, Won Tae Kim, Se Eun Kim, Young Woo Park et Kang Moon Seo. « Combination Auriculopalpebral Nerve Block and Local Anesthesia for Placement of a Nictitating Membrane-to-Superotemporal Bulbar Conjunctiva Flap in Dogs ». Journal of the American Animal Hospital Association 45, n^o 4 (1 juillet 2009) : 164–67. http://dx.doi.org/10.5326/0450164.

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The purpose of this study was to evaluate the efficacy of combined local anesthesia in dogs undergoing nictitating membrane (NM)-to-superotemporal bulbar conjunctiva flap construction. Medical records of 47 dogs that had received local anesthesia for NM-to-superotemporal bulbar conjunctiva flap were reviewed. Combined local anesthetic technique included auriculopalpebral nerve block, topical anesthesia of the eye, and infiltration anesthesia of the superotemporal bulbar conjunctiva and palpebral surface of the NM. Forty-two (89.3%) dogs complied with the anesthetic procedures and underwent NM flap without general anesthesia or sedation. No complications were related to the combined local anesthesia. Combined local anesthesia for NM-to-superotemporal bulbar conjunctiva flap may be a time- and cost-effective method that produces both analgesia of the surgical site and akinesia of the eyelid.

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Santagata, Mario, Roberto De Luca, Giorgio Lo Giudice, Antonio Troiano, Giuseppe Lo Giudice, Giovanni Corvo et Gianpaolo Tartaro. « Arthrocentesis and Sodium Hyaluronate Infiltration in Temporomandibular Disorders Treatment. Clinical and MRI Evaluation ». Journal of Functional Morphology and Kinesiology 5, n^o 1 (6 mars 2020) : 18. http://dx.doi.org/10.3390/jfmk5010018.

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Arthrocentesis in temporomandibular joint disorders can be associated with the intra-articular infiltration of various drugs with the objective of increase treatment efficacy. The aim of this study was to evaluate the clinical indexes variation in patients affected by temporomandibular joint disorders treated with arthrocentesis and sodium hyaluronate (SH) injections. A total of 28 patients suffering from temporomandibular joint disorders underwent one cycle of five arthrocentesis and infiltrations of sodium hyaluronate. Spontaneous mouth opening improved from 36.3 ± 7.5 mm to 45.1 ± 1.9 mm at six months follow-up. A significant reduction in the pain at rest and during mastication mean values emerged at follow-up (p < 0.0001). The mean masticatory efficiency, evaluated through a visual analogic scale, showed improvement at the follow-up period, highlighted by the increase of mean value from a baseline of 3.1 ± 1.2 to a mean value of 8.5 ± 1.2 (p < 0.0001). The mean severity of the joint damage at baseline time was 2.4 ± 0.9 and decreased to 0.4 ± 0.3 at the end of the follow-up period. The decrease in values is confirmed by statistical test (p < 0.05). Our data show how arthrocentesis integrated with sodium hyaluronate infiltrations performed under local anesthesia is a valid method of treating temporomandibular joint disorders.

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Ismail, Mohamed A., Ahmed M. Kamal et Samir Ghobashy. « Comparison of Pain Control during Trus Guided Biopsies between Basal Peri-Prostatic Local Infiltration Anesthesia versus Combined Topical Anal Lignocaine Ointment and Local Infiltration Anesthesia ». Journal of the Egyptian Society of Parasitology 45, n^o 2 (août 2015) : 285–89. http://dx.doi.org/10.12816/0017572.

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ISMAIL, MOHAMED, AHMED KAMAL, SAMIR GHOBASHY, AHMED AL BAZ et MAMDOH ROSHDY. « COMPARISON OF PAIN CONTROL DURING TRUS GUIDED BIOPSIES BETWEEN BASAL PERI-PROSTATIC LOCAL INFILTRATION ANESTHESIA VERSUS COMBINED TOPICAL ANAL LIGNOCAINE OINTMENT AND LOCAL INFILTRATION ANESTHESIA ». Journal of the Egyptian Society of Parasitology 45, n^o 2 (1 août 2015) : 285–89. http://dx.doi.org/10.21608/jesp.2015.89898.

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Kimi, Hiromi, Mikiko Yamashiro et Shuichi Hashimoto. « The Local Pharmacokinetics of 3H-Ropivacaine and 14C-Lidocaine After Maxillary Infiltration Anesthesia in Rats ». Anesthesia Progress 59, n^o 2 (1 juin 2012) : 75–81. http://dx.doi.org/10.2344/11-14.1.

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The effects of infiltration anesthesia with ropivacaine on the dental pulp are considered to be weak. This may be partly associated with its permeation into the oral tissue. With the objective of investigating the local pharmacokinetics of ropivacaine and lidocaine following infiltration anesthesia, we injected 3H-ropivacaine or 14C-lidocaine to the palatal mucosa in rats, measured distributions of radioactivity in the maxilla, and compared the local pharmacokinetics of these agents. The animals were sacrificed at various times and the maxillas were removed. The palatal mucosa and maxillary nerve were resected, and the bone was divided into 6 portions. We measured radioactivity in each tissue and calculated the level of each local anesthetic (n = 8). Lidocaine diffused to the surrounding tissue immediately after the injection, whereas ropivacaine tended to remain in the palatal mucosa for a longer period. Lidocaine showed a higher affinity for the maxillary bone than ropivacaine. There was a correlation between the distribution level of local anesthetics in the maxillary bone and that in the maxillary nerve. The lower-level effects of infiltration anesthesia with ropivacaine on the dental pulp may be because ropivacaine has a high affinity for soft tissue, and its transfer to bone is slight.

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Joannides, Alexis J., Thomas Santarius, Helen M. Fernandes, Rodney J. C. Laing et Rikin A. Trivedi. « Transient perioperative brainstem paralysis secondary to a local anesthetic ». Journal of Neurosurgery : Pediatrics 10, n^o 1 (juillet 2012) : 60–61. http://dx.doi.org/10.3171/2012.3.peds11394.

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Local anesthesia is widely used, in isolation or in conjunction with general anesthesia. The authors describe 2 adolescent patients presenting with absent brainstem reflexes and delayed awakening following elective foramen magnum decompression for Chiari Type I malformation. In both cases, neurological deficits were closely associated with the administration of a levobupivacaine field block following wound closure. In the absence of any structural or biochemical abnormalities, and with spontaneous recovery approximating the anesthetic half-life, the authors' observations are consistent with transient brainstem paralysis caused by perioperative local anesthetic infiltration.

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Suharto, Gusti muhammad Fuad, et Rory Denny Saputra. « Efektivitas Blok Transversus Abdominis Plane Pasca Operasi Caesar ». Jurnal Anestesi Obstetri Indonesia 3, n^o 1 (12 mai 2020) : 59–71. http://dx.doi.org/10.47507/obstetri.v3i1.23.

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Operasi caesar merupakan prosedur bedah yang paling umum dilakukan di seluruh dunia. Operasi ini menyebabkan nyeri pasca operatif sedang hingga berat sebagai akibat insisi pfannenstiel yang umumnya dikaitkan dengan rasa nyeri pada uterus dan somatik pada dinding abdomen. Analgesia pasca operasi yang memadai pada pasien obstetrik sangat penting karena mereka memiliki kebutuhan pemulihan bedah yang berbeda, yaitu meliputi menyusui dan perawatan bayi baru lahir, hal ini dapat terganggu jika analgesia yang diberikan tidak memuaskan. Rejimen analgesik pasca operasi yang ideal harus efektif tanpa mempengaruhi ibu untuk merawat neonates dan dengan efek transfer obat yang seminimal mungkin melalui ASI. Saat ini banyak cara yang paling aman dan efektif dari intervensi manajemen nyeri pasca operasi seperti anestesi lokal dengan infiltrasi kulit, analgesia epidural, dan blok bidang seperti blok transversus abdominis plane (TAP) dan blok ilioinguinal-iliohipogastrik (II-IH). Blok TAP merupakan teknik anestesi regional dimana serabut saraf aferen yang menginervasi dinding abdomen bagian anterolateral diblokir dengan mengguakan anestesi lokal di bidang transversus abdominalis. Potensinya dalam meningkatkan kualitas dan durasi analgesia setelah berbagai operasi abdomen bawah sudah tidak bisa dipungkiri lagi. Sekarang, dengan bantuan USG menjadikan blok TAP sebagai metode yang aman dan efektif untuk memberikan analgesia pasca operasi caesar dibandingkan dengan perawatan standar pasca operasi. Selain itu, blok TAP juga dikaitkan dengan pengurangan konsumsi opioid, peningkatan kepuasan pasien, dan efektif untuk mengurangi nyeri dibandingkan dengan teknik analgesia lainnya. Efficacy of Transversus Abdominis Plane Block After Post Caesarean Section Delivery Abstract Caesarean section is the most common surgical procedure performed worldwide. This operation causes moderate to severe postoperative pain as a result of pfannenstiel incision which is commonly associated with pain in the uterus and somatic in the abdominal wall. Adequate postoperative analgesia in obstetric patients is very important because they have different surgical recovery needs, which include breastfeeding and newborn care, this is can be disrupted if the analgesia given is not satisfactory. The ideal postoperative analgesic rejimen must be effective without affecting the mother to treat the neonate and with minimal effect of drug transfer through breast milk. There are currently many of the safest and effective ways of interventions for postoperative pain management such as local anesthetic skin infiltration, epidural analgesia, and field block like TAP and II-IH. TAP block is a regional anesthetic technique where afferent nerve fibers that innervate the anterolateral abdominal wall are blocked by using local anesthesia in the transverse abdominal plane area. Potential in improving the quality and duration of analgesia after various lower abdominal operations is inevitable. Now, with ultrasound guiding, the TAP block is a safe and effective method for providing analgesia post caesarean section delivery compared to standard postoperative care. In addition, TAP block is also associated with a reduction of opioid consumption, increased patient satisfaction, and is effective in reducing pain compared to other analgesia technique.

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Klöss, Thomas, Gunther Lenz, Heidi Schwandt-Boden, Johannes Bauer et Raimund Stehle. « The Role of Regional Anesthesia under Field Conditions ». Prehospital and Disaster Medicine 5, n^o 4 (décembre 1990) : 349–52. http://dx.doi.org/10.1017/s1049023x00027096.

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AbstractThe authors, who served as anesthesiologists for 15 months at an International Committee of the Red Cross (ICRC) surgical field hospital in a Cambodian refugee camp, report their anesthesiologic experience with 2,906 patients. In spite of preferential use of regional anesthetic techniques, general anesthesia was required in 68% of the cases. Local infiltration anesthesia was applied in 21% of the cases, conduction anesthesia in 3%, and spinal anesthesia in 8%.

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Lee, Mi Geum, Hee Yeon Park, Chang Ki Lee, Joon Hyouk Choi et Yun Suk Choi. « Coronary vasospasm caused by local infiltration of epinephrine after spinal anesthesia ». Korean Journal of Anesthesiology 67, Suppl (2014) : S46. http://dx.doi.org/10.4097/kjae.2014.67.s.s46.

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Malhotra, Vinod, Charles W. Long et Michael J. Meister. « Intercostal Blocks with Local Infiltration Anesthesia for Extracorporeal Shock Wave Lithotripsy ». Anesthesia & ; Analgesia 66, n^o 1 (janvier 1987) : 85???88. http://dx.doi.org/10.1213/00000539-198701000-00015.

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Ginström, Robert, Juha Silvola et Laila Saarnivaara. « Local bupivacaine–epinephrine infiltration combined with general anesthesia for adult tonsillectomy ». Acta Oto-Laryngologica 125, n^o 9 (janvier 2005) : 972–75. http://dx.doi.org/10.1080/00016480510043413.

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Bussolin, Leonardo, Paolo Busoni, Letizia Giorgi, Massimo Crescioli et Andrea Messeri. « Tumescent Local Anesthesia for the Surgical Treatment of Burns and Postburn Sequelae in Pediatric Patients ». Anesthesiology 99, n^o 6 (1 décembre 2003) : 1371–75. http://dx.doi.org/10.1097/00000542-200312000-00020.

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Background Tumescent local anesthesia is a technique for regional anesthesia of the skin and the subcutaneous tissue, using infiltration of large volumes of local anesthetic. The advantages of this technique are (1) simplicity, (2) prolonged postoperative analgesia, (3) low incidence of bleeding, and (4) anesthetization of a large area of the body. There are no reports on the use of tumescent local anesthesia in pediatric patients. Methods In 30 consecutive pediatric burn patients with American Society of Anesthesiologists physical status class I or II who were 1-120 months old (34 +/- 31.6 months), after induction of anesthesia with nitrous oxide-oxygen-sevoflurane, infiltration with 0.05% (14 ml/kg) or 0.1% (7 ml/kg) lidocaine solution was performed. Anesthesia was maintained with patients spontaneously breathing with 1.5% sevoflurane in nitrous oxide-oxygen (50%). The maximum dose of lidocaine used was 7 mg/kg. Postoperative pain was assessed by using the Children's Hospital of Eastern Ontario Pain Scale (for patients aged up to 5 yr) and by using a visual analog scale (for patients older than 5 yr). A comparison with a historic control group not treated with the tumescent local anesthesia technique was performed. Results No patients were excluded from the study, and no significant variations in the monitored intraoperative parameters were observed. Five patients had an increase in heart rate and respiratory rate at the beginning of surgery, and of these, two needed a temporary increase in sevoflurane concentration. After the initial incision, no response to painful stimulus was observed. No complications occurred. Six patients required postoperative acetaminophen administration, and 24 patients did not require analgesic treatment. Conclusions Tumescent local anesthesia with maximum dose of 7 mg/kg lidocaine seems to be safe and the sole possible effective locoregional anesthesia technique for the surgical treatment of noncontiguous pediatric burns.

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Yamashiro, Mikiko, Shuichi Hashimoto, Asako Yasuda et Katsuhisa Sunada. « Epinephrine Affects Pharmacokinetics of Ropivacaine Infiltrated Into Palate ». Anesthesia Progress 63, n^o 2 (1 juin 2016) : 71–79. http://dx.doi.org/10.2344/0003-3006-63.2.71.

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Pulpal anesthesia success rates for ropivacaine following maxillary infiltration anesthesia seem to be low. We investigated the hypothesis that the addition of epinephrine would affect the pharmacokinetics of ropivacaine by retaining ropivacaine in the mucosa of the injected area through the time-dependent distribution of ropivacaine in the rat maxilla and serum following maxillary infiltration anesthesia using 3H-labeled ropivacaine. We then examined the vasoactivity of ropivacaine with or without epinephrine on local peripheral blood flow. The addition of epinephrine to ropivacaine increased ropivacaine concentrations in the palatal mucosa and adjacent maxilla by more than 3 times that of plain ropivacaine at 20 minutes. By observing the autoradiogram of 3H-ropivacaine, plain ropivacaine in the maxilla was remarkably reduced 20 minutes after injection. However, it was definitely retained in the palatal mucosa, hard palate, adjacent maxilla, and maxillary nerve after the administration with epinephrine. Ropivacaine with epinephrine significantly decreased labial blood flow. This study suggests that 10 μg/mL epinephrine added to 0.5% ropivacaine could improve anesthetic efficacy and duration for maxillary infiltration anesthesia over plain ropivacaine.

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Rosa, Andrei, Natalino Francisco da Silva, Alex Semenoff Segundo, Tereza Delle Vedove Semenoff, Alvaro Henrique Borges et Alexandre Meireles Borba. « The Influence of Vasoconstritor Use in Local Anesthesia in Individuals with Chronic Renal Failure ». Journal of Health Sciences 21, n^o 3 (24 septembre 2019) : 269. http://dx.doi.org/10.17921/2447-8938.2019v21n3p269-273.

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AbstractIndividuals with chronic renal failure (CRD) undergo hemodialysis to compensate for systemic-based disease and often develop systemic arterial hypertension (SAH). Such individuals, when needing dental treatment, carry with them the consideration of which type of anesthetic to be used in clinical and surgical interventions. The objective of this study was to evaluate the action of anesthetics with vasoconstrictor (AwV) and without vasoconstrictor (AoV) in individuals with chronic renal failure. Research subjects needed dental treatment, with dental restorations, on the right and left lower dental arch in premolars and / or molars, thus receiving the model of a split-mouth clinical study. In a randomized study, each side of the mandible was subjected to an anesthetic infiltration with only one 1.8 mL tube in two different moments with a minimum interval of 7 days (for one moment with AwV and another AoV moment). The parameters of oxygen saturation (SaO2), heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured 5 minutes before anesthesia, 5, 15 and 30 minutes after anesthesia. The results found in this study showed statistical difference only in SaO2 in the time of 5 minutes after the anesthesia in comparison of the AwV and AoV group, this same result was obtained when only those individuals who, besides nephropathies, had a diagnosis of SAH, were evaluated. The findings of this study highlight the safety of the use of anesthetics, with or without vasoconstrictors since in small amounts, in individuals with CRF with or without associated SAH.Keywords: Renal Insufficiency. Hypertension. Anesthetics, Local.ResumoIndivíduos com insuficiência renal crônica (IRC) em geral são submetidos à hemodiálise para compensação da doença de base sistêmica e frequentemente desenvolvem a hipertensão arterial sistêmica (HAS). Tais indivíduos, ao necessitarem de tratamento odontológico, levam consigo a ponderação de qual tipo de anestésico a ser utilizado em intervenções clínicas e cirúrgicas. O objetivo deste estudo foi avaliar a ação de anestésicos com vasoconstritor (ACV) e sem vasoconstritor (ASV) em indivíduos com insuficiência renal crônica. Os indivíduos da pesquisa tinham necessidade de tratamento odontológico, com restaurações dentárias, no arco dentário inferior direito e esquerdo em pré-molares e/ou molares, recebendo assim o modelo de estudo clínico de boca dividida. De forma aleatória, os hemiarcos inferiores foram submetidos, em dois diferentes momentos com intervalo mínimo de 7 dias, a infiltração anestésica com apenas um tubete de 1,8 mL (para um momento com ACV e outro momento ASV). Foi feita aferição dos parâmetros de saturação de oxigênio (SaO2), frequência cardíaca (FC), pressão arterial sistólica (PAS) e diastólicas (PAD), 5 minutos antes da anestesia, 5, 15 e 30 minutos após a anestesia. Os resultados encontrados neste estudo demonstraram diferença estatística apenas na SaO2 no tempo de 5 minutos após a anestesia em comparação do grupo ACV e ASV, esse mesmo resultado foi obtido quando avaliados apenas os indivíduos que, além de nefropatas, apresentavam diagnóstico de HAS. Os achados deste estudo ressaltam a segurança do uso de anestésicos, com ou sem vasoconstritores desde que em pequenas quantidades, em indivíduos com IRC com ou sem HAS associada.Palavras-chave: Insuficiência Renal. Hipertensão. Anestésicos Locais.

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Ismail, M. « UP-1.106 : Comparison of Pain Control During TRUS Guided Biopsies Between Basal Peri-prostatic Local Infiltration Anesthesia Versus Combined Topical Anal Lignocaine Ointment and Local Infiltration Anesthesia ». Urology 74, n^o 4 (octobre 2009) : S203. http://dx.doi.org/10.1016/j.urology.2009.07.553.

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James, Deeptiman, Faye M. Evans, Ekta Rai et Nobhojit Roy. « Delivering Essential Surgical Care for Lower-limb Musculoskeletal disorders in the Low-Resource Setting ». World Journal of Surgery 45, n^o 10 (29 juin 2021) : 2975–81. http://dx.doi.org/10.1007/s00268-021-06211-3.

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Abstract Background Mismatched surgeon-anesthesiologist ratios often exist in low-resource settings making safe emergency essential surgical care challenging. This study is an audit of emergency essential procedures performed for lower-limb (LL) musculoskeletal disorders (MSD) when an anesthesiologist was unavailable. It aims to identify strategies for safe anesthesia. Methods A 5-year retrospective audit of emergency essential LL orthopedic procedures performed at remote mission hospital in Central India was performed. Out of necessity, a regional anesthesia (RA) protocol was developed in collaboration with anesthesiologists familiar with the setting. The incidence of intraoperative surgical and perioperative anesthesia complications when RA was administered by a surgeon was evaluated. Results During this period, 766 emergency essential LL MSDs procedures were performed. An anesthesiologist was available for only 6/766. RA was administered by a surgeon for 283/766. This included spinal anesthesia (SA) for 267/283 patients, peripheral nerve blocks for 16/283. Local infiltration and/or sedation was administered to 477/766. There were 17 intraoperative surgical complications. Anesthesia-related complications included 37/267 patients who required multiple attempts to localize subarachnoid space and SA failure in 9/267 patients all of whom had successful re-administration. Additional sedation and infiltration of local anesthetic was required in 5/267 patients. Conclusion Remote pre-anesthesia consultation for high-risk patients, local surgeon-anesthesiologist networking, protocol-guided management, and dedicated short duration of training in anesthesia may be considered as an alternative for delivering RA for emergency essential surgery for LL MSDs due to unavailability of anesthesiologists.

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Anisimova, Evgenia N., N. U. Anisimova, R. S. Babadjanyan et M. V. Gromovik. « THE BASIS OF CARRYING OUT OF SAFE LOCAL ANESTHETIC IN OUTPATIENT DENTAL PRACTICE ». Russian Journal of Dentistry 23, n^o 3-4 (15 août 2019) : 144–48. http://dx.doi.org/10.18821/1728-2802-2019-23-3-4-144-148.

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On the basis of clinical and functional studies, a protocol for conducting safe local anesthesia in outpatient dental practice has been developed. The essence of the protocol is anesthesia with the treatment and removal of teeth in the upper jaw and lower jaw in the frontal section using a 4% articaine solution with a vasoconstrictor of 1: 200,000 under the infiltration method of anesthesia with an efficiency of 97.3 ± 1.3%, duration 29.2 ± 2.48 minutes and an MPA of 96.3 ± 1.23% and an injection rate of 1 ml / min; in anesthesia of the molars in the lower jaw using the conductive method at the mandibular orifice with the obligatory aspiration test with 4% articaine with epinephrine 1: 200000 with an efficiency up to 92.54% ± 1.3 and a duration of 35.2 ± 2.43 minutes with a speed drug administration - 1 ml / min. Improving the effectiveness of anesthesia to 95.54 ± 0.3% is achieved by the periodontal method of introducing a 4% solution of articaine with a vasoconstrictor of 1: 200,000.

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Driscoll, MaryKate, Hyun Kee Chung et Manisha S. Desai. « Robert Emmett Farr (1875–1932) : A pioneer of pediatric regional anesthesia ». Journal of Medical Biography 26, n^o 3 (13 juillet 2016) : 182–88. http://dx.doi.org/10.1177/0967772016644362.

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Surgeons influence the introduction and development of anesthesia in many ways. Robert Emmett Farr is frequently cited as the first to describe the use of brachial plexus anesthesia in children. A surgeon based in Minneapolis, Minnesota, he passionately believed that regional anesthesia was superior to general anesthesia for many surgical procedures. He wrote extensively promoting other regional techniques, including local infiltration of local anesthetics for pyloromyotomy and harelip repairs, as well as caudal blocks for lower abdominal procedures. Anesthesia texts from the early 1900’s suggest that regional anesthesia was not popular as a reliable alternative to general anesthesia. Undeterred, Farr continued promoting his view that regional anesthesia was the future of surgery. We examine how Farr promoted regional anesthesia in children and adults, in a way changing surgical practice and improving clinical care. We also hope to highlight the other contributions to medicine made by this pioneer.

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Altug, Hasan Ayberk, Metin Sencimen, Altan Varol, Necdet Kocabiyik, Necdet Dogan et Aydın Gulses. « The Efficacy of Mylohyoid Nerve Anesthesia in Dental Implant Placement at the Edentulous Posterior Mandibular Ridge ». Journal of Oral Implantology 38, n^o 2 (1 avril 2012) : 141–47. http://dx.doi.org/10.1563/aaid-joi-d-10-00037.

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The aim of this study is to evaluate the anesthetic efficacy of mylohyoid and buccal nerve anesthesia at the posterior edentulous mandible versus regional anesthetic block to the inferior alveolar nerve in dental implant surgery. The study was composed of 2 groups. In the first group (group A), 14 voluntary adults (7 female and 7 male) received local infiltrations of 1 mL articaine HCl 4% with epinephrine 1/200 000 to the ipsilateral mylohyoid and buccal nerves. In the second group (group B, control; 9 female and 5 male adults), the inferior alveolar and the buccal nerve blocks were performed. Visual analog scales were obtained from patients to determine the level of pain during incision, drilling, implant placement, and suturing stages of implant surgery. A combination of buccal and mylohyoid nerve block offered an acceptable level of anesthesia. Two patients from group A stopped the ongoing surgery and had extraregional anesthesia by inferior alveolar nerve block. In group B, patients were operated on successfully. Local anesthetic infiltrations of the mylohyoid and the buccal nerve may be considered alternative methods of providing a convenient anesthetic state of the posterior mandibular ridge.

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