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1

1921-, Franks L. M., and Hart I, eds. Tumour progression and metastasis. Oxford University Press for the Imperial CancerResearch Fund, 1988.

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2

Imperial Cancer Research Fund (Great Britain). Tumour progression and metastasis. Edited by Hart I and Hart Ian. Published for the Imperial Cancer Research Fund by Oxford University Press, 1988.

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3

Károly, Lapis, Eckhardt S, and International Union Against Cancer, eds. Carcinogenesis and tumour progression. Akadémiai Kiadó, 1987.

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4

Kaiser, Hans E., and Aejaz Nasir, eds. Selected Aspects of Cancer Progression: Metastasis, Apoptosis and Immune Response. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6729-7.

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1928-, Kaiser Hans E., Nasir Aejaz, and Nasir Nelly Adriana, eds. Selected aspects of cancer progression: Metastasis, apoptosis and immune response. Springer, 2008.

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6

service), ScienceDirect (Online, ed. Bone cancer: Progression and therapeutic approaches. Academic, 2010.

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7

L, Nicolson Garth, Fidler Isaiah J. 1936-, Triton Biosciences Inc, Smith, Kline & French Laboratories., and University of California, Los Angeles., eds. Tumor progression and metastasis: Proceedings of a Triton Biosciences-Smith, Kline & French-UCLA symposium held in Keystone, Colorado, April 6-12, 1987. A.R. Liss, 1988.

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8

Metastatic Progression and Tumour Heterogeneity. MDPI, 2020. http://dx.doi.org/10.3390/books978-3-03928-854-0.

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9

Zannetti, Antonella, Gennaro Ilardi, and Wolfgang Link, eds. Tumor Microenvironment: Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression. Frontiers Media SA, 2021. http://dx.doi.org/10.3389/978-2-88971-448-3.

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Healey, John H., and David McKeown. Orthopaedic surgery in the palliation of cancer. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0125.

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Metastatic spread of cancer to bone is frequent and causes pain, disability, and functional limitation. New understanding of the homing method of cancer cells to bone and the mechanism of cancer production of pain raise possible new treatment strategies. Non-surgical treatments such as chemotherapy and hormone therapy are effective in early disease. Bisphosphonates and inhibition of osteoprotegerin prevent progression of bone lesions and avoid pain, radiation, and surgery. Radiotherapy arrests disease and relieves pain in many cases. Surgery is needed when the bone is weak or fractured. It eff
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11

O’Brien, Tim, and Amit Patel. Kidney cancer. Edited by James W. F. Catto. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0088.

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Despite advances in imaging techniques, many patients with renal cancer still present with locally advanced or metastatic disease. Surgical resection remains the main stay of treatment for locally advanced disease, but is technically challenging and survival remains limited. Progression free and overall survival following nephrectomy are dependent on many factors including pathological T-stage, lymph node status, and Fuhrman grade. Patients presenting with metastatic disease still have a poor prognosis and the use of multimodal therapy has yet to deliver dramatic improvements in outcomes, with
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12

Lasfar, Ahmed, and Karine Cohen-Solal, eds. Tumor Progression and Metastasis. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.77832.

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Mukherji, Deborah, Aurelius Omlin, Carmel Pezaro, and Johann De Bono. Novel therapies and emerging strategies for the treatment of patients with castration-resistant prostate cancer. Edited by James W. F. Catto. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0069.

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Castration-resistant prostate cancer (CRPC) represents a final stage of this malignancy for many men and is defined as the progression of prostate cancer despite castrate levels of testosterone. CRPC may present as a rising PSA, the development of new metastases, or worsening of known metastases. Recent advances have resulted in five new treatments for CRPC: the immunotherapy sipuleucel-T; the cytotoxic cabazitaxel; the androgen biosynthesis inhibitor abiraterone acetate; the radioisotope radium-223; and the antiandrogen enzalutamide. These have all improved overall survival in randomized phas
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14

Montironi, Rodolfo, Liang Cheng, Antonio Lopez-Beltran, Roberta Mazzucchelli, Matteo Santoni, and Marina Scarpelli. Prostate cancer. Edited by James W. F. Catto. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0060.

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The incidence of prostate cancer (PCa) has risen dramatically in the last years. This event may be partially explained by the employment of digital rectal examination (DRE), serum prostate-specific antigen (PSA), and transrectal ultrasonography. In developed countries, PCa is the most frequent non-skin malignancy in males. It is estimated that one in six males will be diagnosed with PCa during their lifetime, the risk of death due to metastatic PCa being 1 in 30. Multiple factors contribute to the development of PCa, as well as to its progression to an androgen-independent state: dietary facto
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15

Gorelik, Elizier L. Metastasis/Dissemination (Cancer Growth and Progression). Springer, 2007.

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16

Arzumanyan, Alla. Liver Cancer: Genesis, Progression and Metastasis. IntechOpen, 2023.

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17

Lemieux, Julie. An exploration of responsiveness to change of psychosocial, quality of life and pain measures to supportive-expressive group therapy intervention, improvement in mood and progression of disease in women with metastatic breast cancer. 2005.

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18

Lemieux, Julie. An exploration of responsiveness to change of psychosocial, quality of life and pain measures to supportive-expressive group therapy intervention, improvement in mood and progression of disease in women with metastatic breast cancer. 2005.

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19

NICHOLSON, GL. Nicolson: Tumor Progression & Metastasis (Proc Keystone Colorado April 1987). John Wiley & Sons Inc, 1988.

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20

Liver Cancer - Genesis, Progression and Metastasis [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.100845.

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21

Clarke, Noel W. Metastatic disease in prostate cancer. Edited by James W. F. Catto. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0068.

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Metastases are the predominant cause of morbidity and death from prostate cancer (CaP). The tendency for cells to migrate from the primary site, enter the vascular/lymphatic circulation, and implant/grow at secondary sites is the principal discriminator of aggressive form indolent disease. But this process is poorly understood. Cells enter the circulation in increasing number as the disease progresses, impinging on endothelial surfaces, particularly in red bone marrow where they bind and transmigrate, forming early cell colonies. This requires chemo-attractants and nutrients enabling cellular
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22

Merakos, Peter. Role of Proprotein Convertases in Cancer Progression and Metastasis. Morgan & Claypool Life Science Publishers, 2014.

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23

Galluzzi, Lorenzo, and Clement Thomas. Actin Cytoskeleton in Cancer Progression and Metastasis - Part B. Elsevier Science & Technology, 2020.

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24

Actin Cytoskeleton in Cancer Progression and Metastasis – Part C. Elsevier, 2021. http://dx.doi.org/10.1016/s1937-6448(21)x0004-4.

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Actin Cytoskeleton in Cancer Progression and Metastasis - Part A. Elsevier, 2020. http://dx.doi.org/10.1016/s1937-6448(20)x0007-4.

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Actin Cytoskeleton in Cancer Progression and Metastasis - Part B. Elsevier, 2020. http://dx.doi.org/10.1016/s1937-6448(20)x0008-6.

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27

Galluzzi, Lorenzo, and Clement Thomas. Actin Cytoskeleton in Cancer Progression and Metastasis - Part B. Elsevier Science & Technology Books, 2020.

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28

Metrakos, Peter, and Majid Khatib. Role of Proprotein Convertases in Cancer Progression and Metastasis. Morgan & Claypool Life Science Publishers, 2012.

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29

Galluzzi, Lorenzo, and Clement Thomas. Actin Cytoskeleton in Cancer Progression and Metastasis - Part C. Elsevier Science & Technology Books, 2021.

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30

Galluzzi, Lorenzo, and Clement Thomas. Actin Cytoskeleton in Cancer Progression and Metastasis - Part A. Elsevier Science & Technology Books, 2020.

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31

Galluzzi, Lorenzo, and Clement Thomas. Actin Cytoskeleton in Cancer Progression and Metastasis - Part C. Elsevier Science & Technology, 2021.

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32

Thomas, Clément, and Lorenzo Galluzzi. Actin Cytoskeleton in Cancer Progression and Metastasis - Part A. Elsevier Science & Technology, 2020.

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33

Smolkova, Bozena, Julie Earl, and Agapi Kataki, eds. Genetic and Epigenetic Regulations of Tumor Progression and Metastasis. MDPI, 2023. http://dx.doi.org/10.3390/books978-3-0365-7184-3.

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34

Tse, Joyce Che Yan. Functional Heterogeneity of Fibroblasts in Cancer Progression and Metastasis. 2011.

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35

Kaiser, Hans E., and Aejaz Nasir. Selected Aspects of Cancer Progression: Metastasis, Apoptosis and Immune Response. Springer Netherlands, 2010.

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36

Khatib, Abdel-Majid. Proprotein Convertases: Discovery, Characteristics, and Link to Tumor Progression and Metastasis. Morgan & Claypool Life Science Publishers, 2013.

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37

Khatib, Abdel-Majid, and A.-Majid Khatib. Proprotein Convertases: Discovery, Characteristics, and Link to Tumor Progression and Metastasis. Morgan & Claypool Life Science Publishers, 2013.

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38

Kaiser, H. E. Comparative Aspects of Tumor Development (Cancer Growth and Progression). Springer, 1988.

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39

Ajithkumar, Thankamma, Ann Barrett, Helen Hatcher, and Natalie Cook. Concepts of multidisciplinary management. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235636.003.0003.

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Cancer prevention 18Cancer screening 22Cancer genetics 24Genetic counselling 28Principles of cancer diagnosis and management 32Principles of surgical oncology 38Radiotherapy 42Principles of systemic therapy 46Carcinogenesis is a multistep process consisting of progressive molecular and cellular changes leading to early invasive cancer and finally to distant metastasis and death. The initiation and progression of cancer usually takes years. Attempts are being made to reverse the molecular and cellular changes at an early state of cancer initiation or progression. The World Health Organization (
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40

Simon, M. Celeste. Diverse Effects of Hypoxia on Tumor Progression. Springer, 2011.

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41

Simon, M. Celeste. Diverse Effects of Hypoxia on Tumor Progression. Springer, 2012.

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42

Michelson, S. Mathematical Modeling in Tumor Growth and Progression (Invasion and Metastasis, 4-5). S Karger Pub, 1997.

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43

Gvozdenovic, Ana. The relevance of CD44 and hyaluronan interaction in osteosarcoma progression and metastasis. 2012.

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44

Eisen, Tim. The patient with renal cell cancer. Edited by Giuseppe Remuzzi. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0172.

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Renal cancer is the commonest malignancy of the kidney and worldwide, accounts for between 2% and 3% of the total cancer burden. The mainstay of curative treatment remains surgery. There have been significant advances in surgical technique, the most important ones being nephron-sparing surgery and laparoscopic nephrectomy. The medical treatment of advanced renal cell cancer has only improved markedly in the last decade with the development of antiangiogenic tyrosine-kinase inhibitors, inhibitors of mammalian target of rapamycin, and a diminished role for immunotherapy.Tyrosine-kinase inhibitor
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45

Diverse Effects of Hypoxia on Tumor Progression (Current Topics in Microbiology and Immunology Book 345). Springer, 2010.

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46

Wang, Xu, Tengchuan Jin, Christopher James Pirozzi, Xueli Zhang, and Shu-Heng Jiang, eds. Inflammatory Tumor Immune Microenvironment: Molecular Mechanisms and Signaling Pathways in Cancer Progression and Metastasis. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88974-754-2.

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47

Ganapathy, Vadivel, Maria E. Mycielska, Eric Kenneth Parkinson, and Sebastian Haferkamp, eds. Metabolite and Nutrient Transporters in Cancer-Cell Metabolism: Role in Cancer Progression and Metastasis. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88976-768-7.

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48

Lau, Allison Nicole. Characterization of lung tumor-propagating cells reveals a role for CD24 and Yap/Taz in lung cancer progression and metastasis. 2014.

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49

Lippman, Marc E., and Robert B. Dickson. Mammary Tumorigenesis and Malignant Progression: Advances in Cellular and Molecular Biology of Breast Cancer. Springer, 2012.

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Mammary Tumorigenesis and Malignant Progression: Advances in Cellular and Molecular Biology of Breast Cancer (Cancer Treatment and Research). Springer, 1994.

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