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Articles de revues sur le sujet « Natural Brain Tonic »

Auteur : Grafiati

Publié le 2 juin 2025

Mis à jour le 31 juillet 2025

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1

El Amki, Mohamad, Nadine Binder, Riccardo Steffen, et al. "Contraceptive drugs mitigate experimental stroke-induced brain injury." Cardiovascular Research 115, no. 3 (2018): 637–46. http://dx.doi.org/10.1093/cvr/cvy248.

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AbstractAimsEffective stroke treatments beyond reperfusion remain scant. The natural steroid hormone progesterone has shown protective effects in experimental models of brain injury and cardiovascular disease. However, unfavourable bioavailability limits its clinical use. Desogestrel and drospirenone are new generation progestins with progesterone-like properties, developed as oral contraceptives with excellent bioavailability and safety profile. We investigated the neuroprotective properties of these progestins in vivo using transient middle cerebral artery occlusion (MCAO) and in vitro using

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Sbrini, Giulia, Paola Brivio, Marco Fumagalli, et al. "Centella asiatica L. Phytosome Improves Cognitive Performance by Promoting Bdnf Expression in Rat Prefrontal Cortex." Nutrients 12, no. 2 (2020): 355. http://dx.doi.org/10.3390/nu12020355.

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A wide range of people in the world use natural remedies as primary approaches against illnesses. Accordingly, understanding the mechanisms of action of phytochemicals has become of great interest. In this context, Centella asiatica L. is extensively used, not only as anti-inflammatory or antioxidant agent but also as brain tonic. On this basis, the purpose of this study was to evaluate whether the chronic administration of C. asiatica L. to adult male rats was able to improve the expression of Bdnf, one of the main mediators of brain plasticity. Moreover, we assessed whether the treatment cou

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Chiang, Nancy, Shahla Ray, Jade Lomax, et al. "Modulation of Brain-Derived Neurotrophic Factor (BDNF) Signaling Pathway by Culinary Sage (Salvia officinalis L.)." International Journal of Molecular Sciences 22, no. 14 (2021): 7382. http://dx.doi.org/10.3390/ijms22147382.

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Culinary sage (Salvia officinalis L.) is a common spice plant in the mint family (Lamiaceae) well known for its distinctive culinary and traditional medicinal uses. Sage tea has been used traditionally as a brain-enhancing tonic and extracts from sage have been reported to have both cognitive and memory enhancing effects. Brain-derived neurotrophic factor (BDNF) is an endogenous signaling molecule involved in cognition and memory function. In this study, activity-guided fractionation employing preparative reverse-phase high performance liquid chromatography (RP-HPLC) of culinary sage extracts

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Zhornitsky, Simon, Isha Dhingra, Thang M. Le, Wuyi Wang, Chiang-shan R. Li, and Sheng Zhang. "Reward-Related Responses and Tonic Craving in Cocaine Addiction: An Imaging Study of the Monetary Incentive Delay Task." International Journal of Neuropsychopharmacology 24, no. 8 (2021): 634–44. http://dx.doi.org/10.1093/ijnp/pyab016.

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Abstract Background Cocaine addiction is associated with altered sensitivity to natural reinforcers and intense drug craving. However, previous findings on reward-related responses were mixed, and few studies have examined whether reward responses relate to tonic cocaine craving. Methods We combined functional magnetic resonance imaging and a monetary incentive delay task to investigate these issues. Imaging data were processed with published routines, and the results were evaluated with a corrected threshold. We compared reward responses of 50 cocaine-dependent individuals (CDs) and 45 health

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Tejaswini, Taware* Sakshi Shahu Sunil Bhagat Dr. Swati Deshmukh. "Green Tea Catechins-Based Herbal Churna: A Novel Approach for Alzheimer's Disease Treatment." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2668–85. https://doi.org/10.5281/zenodo.15435844.

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In the long struggle to overcome the powerful forces of nature, the human beings have always turned towards plants for food, shelter, clothing, and healing. Even today herbal medicine plays an important role in the management of diseases. Though we are in 21st century where modern technology and scientific discoveries are ushering remarkable changes in our lives, nevertheless, the story of plants as herbal medicines definitely continues to unfold, however, quietly and independently. Synthetic drugs are being prepared by keeping the natural drugs as standards but the efficacy of the herbal drug

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Cassaglia, Priscila A., Robert I. Griffiths, and Adrian M. Walker. "Cerebral sympathetic nerve activity has a major regulatory role in the cerebral circulation in REM sleep." Journal of Applied Physiology 106, no. 4 (2009): 1050–56. http://dx.doi.org/10.1152/japplphysiol.91349.2008.

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Sympathetic nerve activity (SNA) in neurons projecting to skeletal muscle blood vessels increases during rapid-eye-movement (REM) sleep, substantially exceeding SNA of non-REM (NREM) sleep and quiet wakefulness (QW). Similar SNA increases to cerebral blood vessels may regulate the cerebral circulation in REM sleep, but this is unknown. We hypothesized that cerebral SNA increases during phasic REM sleep, constricting cerebral vessels as a protective mechanism against cerebral hyperperfusion during the large arterial pressure surges that characterize this sleep state. We tested this hypothesis u

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Sosnik, Ronen, Sebastian Haidarliu, and Ehud Ahissar. "Temporal Frequency of Whisker Movement. I. Representations in Brain Stem and Thalamus." Journal of Neurophysiology 86, no. 1 (2001): 339–53. http://dx.doi.org/10.1152/jn.2001.86.1.339.

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How does processing of information change the internal representations used in subsequent stages of sensory pathways? To approach this question, we studied the representations of whisker movements in the lemniscal and paralemniscal pathways of the rat vibrissal system. We recently suggested that these two pathways encode movement frequency in different ways. We proposed that paralemniscal thalamocortical circuits, functioning as phase-locked loops (PLLs), translate temporally coded information into a rate code. Here we focus on the two major trigeminal nuclei of the brain stem, nucleus princip

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Łuszczki, Jarogniew J., Hubert Bojar, Agnieszka Góralczyk, and Krystyna Skalicka-Woźniak. "Antiseizure Effects of Scoparone, Borneol and Their Impact on the Anticonvulsant Potency of Four Classic Antiseizure Medications in the Mouse MES Model—An Isobolographic Transformation." International Journal of Molecular Sciences 24, no. 2 (2023): 1395. http://dx.doi.org/10.3390/ijms24021395.

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Numerous botanical drugs containing coumarins and terpenes are used in ethnomedicine all over the world for their various therapeutic properties, especially those affecting the CNS system. The treatment of epilepsy is based on antiseizure medications (ASMs), although novel strategies using naturally occurring substances with confirmed antiseizure properties are being developed nowadays. The aim of this study was to determine the anticonvulsant profiles of scoparone (a simple coumarin) and borneol (a bicyclic monoterpenoid) when administered separately and in combination, as well as their impac

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Pieróg, Mateusz, Katarzyna Socała, Elżbieta Wyska, Ewa Poleszak, and Piotr Wlaź. "Effect of Ellagic Acid on Seizure Threshold in Two Acute Seizure Tests in Mice." Molecules 26, no. 16 (2021): 4841. http://dx.doi.org/10.3390/molecules26164841.

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Ellagic acid (EA) is a natural dietary polyphenol that has many beneficial properties, including anti-inflammatory, antioxidant, antiviral, antibacterial, and neuroprotective effects. Studies have revealed that EA may modulate seizure activity in chemically induced animal models of seizures. Therefore, the aim of the present study was to investigate the effect of EA on the seizure threshold in two acute seizure tests in male mice, i.e., in the intravenous (i.v.) pentylenetetrazole (PTZ) seizure test and in the maximal electroshock seizure threshold (MEST) test. The obtained results showed that

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SHAHRAJABIAN, Mohamad Hesam, and Wenli SUN. "Study of two important medicinal plants, common sage and five flavor berries." Notulae Scientia Biologicae 16, no. 4 (2024): 12050. https://doi.org/10.55779/nsb16412050.

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Sage (Salvia officinalis L.) of the Lamiaceae family contains a healthy dose of vitamins, minerals and rich in several nutrients. Schisandra berry (Schisandra chinensis (Turcz.) Baill. (Magnoliaceae) or Wu-Wei-Zi, which means the fruit of five tastes, is a generally used herb in traditional Chinese medicine (TCM). The five tastes of Schisandra berry refer to its impact on the five visceral organs in the body. S. chinensis has been utilized to treat sleep disorders and a tonic for kidney and brain in traditional Chinese medicine. The five important components of S. chinensis are Schisandrol B,

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Moezi, Leila, Siranoush Yahosseini, Akram Jamshizadeh, and Fateme Pirsalami. "Acute Boldine Treatment Induces Anti-convulsant Effects in Mice through its Antioxidant Activity." Drug Research 69, no. 04 (2018): 227–33. http://dx.doi.org/10.1055/a-0659-2478.

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AbstractBoldine is a natural antioxidant that exhibits some important pharmacological properties, which is due to its free radical scavenging effects. And at the same time, reactive oxygen species (ROS) has an important role in pathogenesis of seizure; hence, reducing it via antioxidants like boldine seems to be effective in treating seizure. This study was designed to investigate whether acute treatment with boldine could alter seizures induced by pentylenetetrazole or electroshock in mice. We also evaluated to see if boldine’s antioxidant properties play a role in its anti-convulsant activit

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Tattersall, J. E., F. Cervero, and B. M. Lumb. "Viscerosomatic neurons in the lower thoracic spinal cord of the cat: excitations and inhibitions evoked by splanchnic and somatic nerve volleys and by stimulation of brain stem nuclei." Journal of Neurophysiology 56, no. 5 (1986): 1411–23. http://dx.doi.org/10.1152/jn.1986.56.5.1411.

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Single-unit electrical activity has been recorded from 95 viscerosomatic neurons in the T9 and T11 segments of the cat's spinal cord. These neurons were excited by electrical and/or natural stimulation of visceral and somatic afferent fibers. The excitatory and inhibitory effects on these neurons of volleys in somatic and visceral afferent fibers and of electrical and chemical stimulation of the nucleus raphe magnus (NRM) and adjacent areas of the reticular formation (Ret. F.) have been studied. Electrical stimulation of the splanchnic nerve produced, after the initial excitation of the neuron

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Dwivedi, Vaibhav, and Harikesh Maurya. "A Comprehensive Overview of Celastrus paniculatus Seed Oil Intended for the Management of Human Ailments." Indian Journal of Pharmaceutical and Biological Research 6, no. 02 (2018): 37–42. http://dx.doi.org/10.30750/ijpbr.6.2.7.

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Celastrus paniculatus belonging to the family Celastraceae generally known as the black oil plant or Malkangani or Jyotishmati. The scrambling through a yellowish corky bark, climbing poly gamodioecious category of shrub requires support to climbs up and distributed almost all over India at the altitude of 2000 m. The seeds are also reported as anxiolytic and anticonvulsant properties, while the root and its bark considered being useful for the treatment of malaria, cancer, and brain-tonic. Plant of Jyotishmati are broadly used in the Ayurvedic system of the medicine to cure many diseases such

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Rukavishnikov, V. S., O. L. Lakhman, S. F. Shayakhmetov, et al. "Results of fundamental studies of the East Siberian Institute of medical and environmental studies on the main problems of occupational health and human ecology (to the 60th anniversary of the Institute)." Russian Journal of Occupational Health and Industrial Ecology, no. 4 (May 22, 2019): 196–205. http://dx.doi.org/10.31089/1026-9428-2019-59-4-196-205.

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The solution of modern problems of occupational health and human ecology not only gives the possibility of implementating measures aimed at improving the health of workers, but also determines the future quality of life of the population. Implementation of basic research focused on the study of the pathogenesis of leading occupational and environmentally related diseases, and the development of scientific and practical measures to improve methods of diagnosis, treatment and prevention remain the main activities of the Institute and meet the priorities of the strategy of scientific and technolo

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Meng, Hui, Andrea M. Green, J. David Dickman, and Dora E. Angelaki. "Pursuit—Vestibular Interactions in Brain Stem Neurons During Rotation and Translation." Journal of Neurophysiology 93, no. 6 (2005): 3418–33. http://dx.doi.org/10.1152/jn.01259.2004.

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Under natural conditions, the vestibular and pursuit systems work synergistically to stabilize the visual scene during movement. How translational vestibular signals [translational vestibuloocular reflex (TVOR)] are processed in the premotor pathways for slow eye movements continues to remain a challenging question. To further our understanding of how premotor neurons contribute to this processing, we recorded neural activities from the prepositus and rostral medial vestibular nuclei in macaque monkeys. Vestibular neurons were tested during 0.5-Hz rotation and lateral translation (both with ga

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Akshay, Tale* Amol Sawale Atul Mehakare Aman Nandurkar Aditya Fande. "Formulation Development Evaluation of Brain Boosting Jelly Containing Shankhapushpi and Almond Extract." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3854–67. https://doi.org/10.5281/zenodo.15490600.

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The growing incidence of mental health concerns, cognitive decline due to aging, and stress-related impairments has intensified interest in safe, natural cognitive enhancers. This study explores the formulation and evaluation of a brain-boosting jelly that integrates the cognitive-supportive properties of Shankhpushpi (Convolvulus pluricaulis) with the nutritional value of almond (Prunus dulcis) extract. Traditionally recognized in Ayurveda as a "Medhya Rasayana," Shankhpushpi is valued for enhancing memory and reducing anxiety, largely due to its alkaloids and flavonoids. Almonds, rich in vit

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Stanojlovic, Olivera, Dragana Zivanovic, Slobodan Mirkovic, and Danijela Vucevic. "Behavioral and electroencephalographic effects of delta sleep inducing peptide and its analogue on metaphit-induced audiogenic seizures in rats." Srpski arhiv za celokupno lekarstvo 132, no. 11-12 (2004): 421–26. http://dx.doi.org/10.2298/sarh0412421s.

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INTRODUCTION Delta sleep inducing peptide (DSIP) is well known natural somnogenic peptide that has many other physiological functions. DSIP analogues representing hepta-and octapeptides (also known as long) as well as tetrapeptide (termed short, used in our experiments) were synthesized with a view to evaluate the peptide specificity in sleep. The effects of DSIP and its analogue DSIP1-4 on metaphit 1-[1(3-isothiocyanatophenyl-ciclohexyl)-piperidine] induced audiogenic seizures were evaluated in rats. METHODS Male Wistar albino rats were divided into 4 groups: 1. Saline; 2. Metaphit; 3. Metaph

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Datta, S., and J. A. Hobson. "Neuronal activity in the caudolateral peribrachial pons: relationship to PGO waves and rapid eye movements." Journal of Neurophysiology 71, no. 1 (1994): 95–109. http://dx.doi.org/10.1152/jn.1994.71.1.95.

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1. The present study was performed to examine the hypothesis that the caudolateral peribrachial area (C-PBL) may be directly involved in shifting the brain from the nonpontogeniculooccipital (non-PGO)-related states of waking (W) and slow-wave sleep (S) to the PGO-related states of slow-wave sleep with PGO waves (SP) and rapid eye movement (REM) sleep. 2. To test this hypothesis at the cellular level, we have recorded a sample of 226 spontaneously discharging units of the C-PBL during natural sleep-waking cycles in unanesthetized head-restrained cats and have correlated the action-potential da

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Soret, Marc, and Marina Ville. "Lissajous-toric knots." Journal of Knot Theory and Its Ramifications 29, no. 01 (2020): 2050003. http://dx.doi.org/10.1142/s0218216520500030.

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A point in the [Formula: see text]-torus knot in [Formula: see text] goes [Formula: see text] times along a vertical circle while this circle rotates [Formula: see text] times around the vertical axis. In the Lissajous-toric knot [Formula: see text], the point goes along a vertical Lissajous curve (parametrized by [Formula: see text] while this curve rotates [Formula: see text] times around the vertical axis. Such a knot has a natural braid representation [Formula: see text] which we investigate here. If [Formula: see text], [Formula: see text] is ribbon; if [Formula: see text], [Formula: see

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Wang, Ban. "Chapter Eight: Toxic Colonialism, Alienation, and Posthuman Dystopia in Chen Qiufan." Prism 19, S1 (2022): 135–50. http://dx.doi.org/10.1215/25783491-10259442.

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Abstract Chen Qiufan's sci-fi novel Waste Tide attests to the dual alienation of nature and humans. Global capitalism, geopolitical conflict, the scramble for natural resources, and rash development have destroyed the rural community, ruined the health of local populations, and eroded the natural environment. Technical advances—artificial intelligence, brain-computer interface, biochemical technologies, and cyborg construction—aggravate metabolic rifts in the human-nature relations, threatening human bodies, regional culture, and local traditions. Driven by profit motives and the desire for po

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Pavlenko, Oleksii, Ihor Shcherbak, Viktoriia Hura, Valentyn Lihus, Iryna Maidaniuk, and Tamara Skoryk. "Development of Music Education in Virtual and Extended Reality." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 13, no. 3 (2022): 308–19. http://dx.doi.org/10.18662/brain/13.3/369.

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The relevance of the chosen topic of the paper is determined by the need to study the development of music education in our time in virtual and augmented reality, focused on the study of new vectors of music education in Ukraine and its entry into the world educational and cultural space based on innovative technologies. The study aims to define and justify the development of music education in virtual and augmented reality, research of innovative technologies to expand the possibilities of the creative process in the art of music, and definition of methods of musical expansion reality. The pa

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Oleksii, PAVLENKO, SHCHERBAK Ihor, HURA Viktoriia, LIHUS Valentyn, MAIDANIUK Iryna, and SKORYK Tamara. "Development of Music Education in Virtual and Extended Reality." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 13, no. 3 (2025): 308–19. https://doi.org/10.18662/brain/13.3/369.

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 The relevance of the chosen topic of the paper is determined by the need to study the development of music education in our time in virtual and augmented reality, focused on the study of new vectors of music education in Ukraine and its entry into the world educational and cultural space based on innovative technologies. The study aims to define and justify the development of music education in virtual and augmented reality, research of innovative technologies to expand the possibilities of the creative process in the art of music, and definition of met

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Simbotin, Dan Gabriel, and Paniel Reyes Cardenas. "Classical Logic, Some of its Limits, and the Psychological Normality." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 15, no. 3 (2024): 249. http://dx.doi.org/10.70594/brain/15.3/19.

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This article identifies some situations of linguistic ambiguities and how general logic tries to solve them and it analyzes the influence it can have in particular situations. Since the topic is vast, we stopped at the ambiguities of language caused by identity. First, the attempt to solve the problem was the enunciation of the laws of logic, namely the principle of identity, and we followed its limits. There are analyzed three aspects emphasizing the degree of remaining ambiguity: the relationship between intension and extension, vague terms, and symbolical-metaphorical thinking. Each of the

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Dan, Gabriel Sîmbotin, and Reyes Cardenas Paniel. "Classical Logic, Some of its Limits, and the Psychological Normality." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 15, no. 3 (2024): 249–57. https://doi.org/10.70594/brain/15.3/19.

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This article identifies some situations of linguistic ambiguities and how general logic tries to solve them and it analyzes the influence it can have in particular situations. Since the topic is vast, we stopped at the ambiguities of language caused by identity. First, the attempt to solve the problem was the enunciation of the laws of logic, namely the principle of identity, and we followed its limits. There are analyzed three aspects emphasizing the degree of remaining ambiguity: the relationship between intension and extension, vague terms, and symbolical-metaphorical thinking. Each of the

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Sevasti Kapsi and Spyridoula Katsantoni. "The role of ICTs on the function of sleep and its effects on learning and brai." GSC Advanced Research and Reviews 16, no. 1 (2023): 139–48. http://dx.doi.org/10.30574/gscarr.2023.16.1.0309.

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Numerous strategies have the potential to improve learning. Since memory is a fundamental cognitive skill that underpins learning, many approaches are employed in education to enhance it. If learning is a natural process, does this mean that there is a natural mechanism that supports learning? It is confirmed in this review that sleep is such a mechanism. According to the population's age, various effects of sleep on the brain and learning are supported by the research on this topic. For proper brain development and cognition, sleep is a crucial activity. In order to effectively exploit this k

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Sevasti, Kapsi, and Katsantoni Spyridoula. "The role of ICTs on the function of sleep and its effects on learning and brai." GSC Advanced Research and Reviews 16, no. 1 (2023): 139–48. https://doi.org/10.5281/zenodo.8272052.

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Numerous strategies have the potential to improve learning. Since memory is a fundamental cognitive skill that underpins learning, many approaches are employed in education to enhance it. If learning is a natural process, does this mean that there is a natural mechanism that supports learning? It is confirmed in this review that sleep is such a mechanism. According to the population's age, various effects of sleep on the brain and learning are supported by the research on this topic. For proper brain development and cognition, sleep is a crucial activity. In order to effectively exploit th

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Lenska, Svitlana, Nataliia Naumovska, Nataliia Rudakova, Olesia Naumovska, Tamara Marchii-Dmytrash, and Andrii Sova. "Neuropedagogical and Psychological Aspects of Play." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 13, no. 4 (2022): 104–21. http://dx.doi.org/10.18662/brain/13.4/378.

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A new article by Ukrainian experts in ethno-pedagogy for the first time in science maximally summarizes the neuro-pedagogical, psychological and social potential of human development through the reproduction of folk games. The aim of the article is not only to consider the thematic diversity, but also to demonstrate how Ukrainian folk children's games and ancient adult games have a natural influence on the formation of worldview, socialization and maturity with the involvement of physical, neurophysiological and psycho-pedagogical mechanisms. Using general scientific, historical and neuroscien

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Jha, Niraj Kumar, Rohan Kar, and Rituraj Niranjan. "ABC Transporters in Neurological Disorders: An Important Gateway for Botanical Compounds Mediated Neuro-Therapeutics." Current Topics in Medicinal Chemistry 19, no. 10 (2019): 795–811. http://dx.doi.org/10.2174/1568026619666190412121811.

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Neurodegeneration is a distinguishing feature of many age related disorders and other vector borne neuroinflammatory diseases. There are a number of factors that can modulate the pathology of these disorders. ATP-binding cassette (ABC) transporters are primarily involved in the maintenance of normal brain homeostasis by eliminating toxic peptides and compounds from the brain. Also, ABC transporters protect the brain from the unwanted effects of endogenous and exogenous toxins that can enter the brain parenchyma. Therefore, these transporters have the ability to determine the pathological outco

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Pluta, Ryszard, Wanda Furmaga-Jabłońska, Sławomir Januszewski, and Stanisław J. Czuczwar. "Post-Ischemic Brain Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Possible Therapeutic Role of Curcumin." Nutrients 14, no. 2 (2022): 248. http://dx.doi.org/10.3390/nu14020248.

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For thousands of years, mankind has been using plant extracts or plants themselves as medicinal herbs. Currently, there is a great deal of public interest in naturally occurring medicinal substances that are virtually non-toxic, readily available, and have an impact on well-being and health. It has been noted that dietary curcumin is one of the regulators that may positively influence changes in the brain after ischemia. Curcumin is a natural polyphenolic compound with pleiotropic biological properties. The observed death of pyramidal neurons in the CA1 region of the hippocampus and its atroph

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Capucciati, Andrea, Fabio A. Zucca, Enrico Monzani, Luigi Zecca, Luigi Casella, and Tim Hofer. "Interaction of Neuromelanin with Xenobiotics and Consequences for Neurodegeneration; Promising Experimental Models." Antioxidants 10, no. 6 (2021): 824. http://dx.doi.org/10.3390/antiox10060824.

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Neuromelanin (NM) accumulates in catecholamine long-lived brain neurons that are lost in neurodegenerative diseases. NM is a complex substance made of melanic, peptide and lipid components. NM formation is a natural protective process since toxic endogenous metabolites are removed during its formation and as it binds excess metals and xenobiotics. However, disturbances of NM synthesis and function could be toxic. Here, we review recent knowledge on NM formation, toxic mechanisms involving NM, go over NM binding substances and suggest experimental models that can help identifying xenobiotic mod

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Fisher, Eddie John Paul, Yorkys Santana Gonzalez, and Eddie Fisher. "Increasing Brain Power beyond Imagination-Aligning Neuroscience and Social Psychology to Aid Prevention." Business and Economic Research 7, no. 2 (2017): 82. http://dx.doi.org/10.5296/ber.v7i2.11301.

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Brain science and cognitive psychology are in high demand amongst professions such as social psychology, education and science. Advancing the capabilities of the human brain in terms of power to benefit society and improve people’s lives has become a topic of increasing value and interest to social psychologists. This research, limited to a literature review and a number of face to face interviews with psychology students to add some contemporary perspectives, investigated how increases in brain power could be achieved and what the potential benefits could be to social psychologists. Results s

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Svitlana, LENSKA1, NAUMOVSKA Nataliia, RUDAKOVA Nataliia, NAUMOVSKA Olesia, MARCHII DMYTRASH Tamara, and SOVA Andrii. "Neuropedagogical and Psychological Aspects of Play." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 13, no. 4 (2025): 104–21. https://doi.org/10.18662/brain/13.4/378.

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 A new article by Ukrainian experts in ethno-pedagogy for the first time in science maximally summarizes the neuro-pedagogical, psychological and social potential of human development through the reproduction of folk games. The aim of the article is not only to consider the thematic diversity, but also to demonstrate how Ukrainian folk children's games and ancient adult games have a natural influence on the formation of worldview, socialization and maturity with the involvement of physical, neurophysiological and psycho-pedagogical mechanisms. Using&nbsp

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Samarghandian, Saeed, Tahereh Farkhondeh, and Mohsen Azimi-Nezhad. "Protective Effects of Chrysin Against Drugs and Toxic Agents." Dose-Response 15, no. 2 (2017): 155932581771178. http://dx.doi.org/10.1177/1559325817711782.

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Issues: Polyphenolic compounds, especially flavonoids, are known as the most common chemical class of phytochemicals, which possess a multiple range of health-promoting effects. Flavonoids are ubiquitous in nature. They are also present in food, providing an essential link between diet and prevention of several diseases. Approach: Chrysin (CH), a natural flavonoid, was commonly found in propolis and honey and traditionally used in herbal medicine. A growing body of scientific evidence has shown that CH possesses protective effects against toxic agents in various animal tissues, including brain

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Shaheryar, Zaib Ali, Mahtab Ahmad Khan, Huma Hameed, et al. "Natural Fatty Acid Guards against Brain Endothelial Cell Death and Microvascular Pathology following Ischemic Insult in the Presence of Acute Hyperglycemia." Biomedicines 11, no. 12 (2023): 3342. http://dx.doi.org/10.3390/biomedicines11123342.

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Ischemic stroke is worsened by the presence of sudden high blood sugar levels, even in individuals without pre-existing diabetes. This elevated glucose concentration hampers the ability of energy-starved brain cells to efficiently use it as a source of energy. Consequently, this leads to the production of abundant amounts of toxic glucose metabolites, which trigger oxidative stress in the brain milieu, particularly in the microvasculature of the brain. A prominent feature of this oxidative stress is the demise of endothelial cells, causing detrimental changes in blood vessels, including a redu

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Kasturirangan, S., G. Shankar, D. Selkoe, and M. Sierks. "P3.085 Novel bio-panning technique to isolate scFv against low concentrations of toxic natural brain derived Abeta oligomers." Parkinsonism & Related Disorders 15 (December 2009): S170. http://dx.doi.org/10.1016/s1353-8020(09)70649-2.

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Bukharin, O. V. "Mechanisms of the natural defenses of hosts to infection." Вестник Российской академии наук 89, no. 8 (2019): 844–50. http://dx.doi.org/10.31857/s0869-5873898844-850.

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The relationship of humans and microbes is an eternal topic. Do microbes bring any benefits or only harm? As years pass, new microbiological technologies appear, new facts regarding the coexistence of microbes and human are discovered, and new understanding of our life together with microbes is achieved. The mechanisms of the host’s natural defenses from infection are considered in this article, with three participants of this chain examined in particular: the hypothalamic-pituitary system, oxytocin, and microbiota. Outwardly, these structures are independent of each other: the central switchb

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Fakhlaei, Rafieh, Jinap Selamat, Alfi Khatib, et al. "The Toxic Impact of Honey Adulteration: A Review." Foods 9, no. 11 (2020): 1538. http://dx.doi.org/10.3390/foods9111538.

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Honey is characterized as a natural and raw foodstuff that can be consumed not only as a sweetener but also as medicine due to its therapeutic impact on human health. It is prone to adulterants caused by humans that manipulate the quality of honey. Although honey consumption has remarkably increased in the last few years all around the world, the safety of honey is not assessed and monitored regularly. Since the number of consumers of honey adulteration have increased in recent years, their trust and interest in this valuable product has decreased. Honey adulterants are any substances that are

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Lee, Joo-Hee, Na-Hyun Ahn, Su-Bin Choi, Youngeun Kwon, and Seung-Hoon Yang. "Natural Products Targeting Amyloid Beta in Alzheimer’s Disease." International Journal of Molecular Sciences 22, no. 5 (2021): 2341. http://dx.doi.org/10.3390/ijms22052341.

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Alzheimer’s disease (AD) is a neurodegenerative disease characterized by severe brain damage and dementia. There are currently few therapeutics to treat this disease, and they can only temporarily alleviate some of the symptoms. The pathogenesis of AD is mainly preceded by accumulation of abnormal amyloid beta (Aβ) aggregates, which are toxic to neurons. Therefore, modulation of the formation of these abnormal aggregates is strongly suggested as the most effective approach to treat AD. In particular, numerous studies on natural products associated with AD, aiming to downregulate Aβ peptides an

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Kravanja, Gregor, Mateja Primožič, Željko Knez, and Maja Leitgeb. "Chitosan-Based (Nano)Materials for Novel Biomedical Applications." Molecules 24, no. 10 (2019): 1960. http://dx.doi.org/10.3390/molecules24101960.

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Chitosan-based nanomaterials have attracted significant attention in the biomedical field because of their unique biodegradable, biocompatible, non-toxic, and antimicrobial nature. Multiple perspectives of the proposed antibacterial effect and mode of action of chitosan-based nanomaterials are reviewed. Chitosan is presented as an ideal biomaterial for antimicrobial wound dressings that can either be fabricated alone in its native form or upgraded and incorporated with antibiotics, metallic antimicrobial particles, natural compounds and extracts in order to increase the antimicrobial effect. S

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Maidaniuk, Iryna, Tetiana Tsoi, Ihor Hoian, Maksym Doichyk, Oksana Patlaichuk, and Olga Stupak. "The Problem of Artificial Intelligence in Contemporary Philosophy." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 13, no. 4 (2022): 436–49. http://dx.doi.org/10.18662/brain/13.4/397.

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The importance of the topic of the article is due to the fact that nowadays there is a need to understand that the creation of artificial intelligence is associated with the understanding and study of natural intelligence. The problem of defining artificial intelligence is largely reduced to defining intelligence in general: is intelligence monolithic or does this concept define a set of different abilities? To what extent intelligence can be created? Is it possible to create computers with intelligence? These and other questions have not yet been answered by the contemporary science, but thes

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Silbergeld, Ellen K., Jodi A. Flaws, and Ken M. Brown. "Organizational and activational effects of estrogenic endocrine disrupting chemicals." Cadernos de Saúde Pública 18, no. 2 (2002): 495–504. http://dx.doi.org/10.1590/s0102-311x2002000200014.

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Endocrine disruption is a hypothesis of common mode of action that may define a set of structurally varied chemicals, both natural and synthetic. Their common mode of action may suggest that they produce or contribute to similar toxic effects, although this has been difficult to demonstrate. Insights from developmental biology suggest that development of hormone sensitive systems, such as the brain and the genitourinary tract, may be particularly sensitive to EDCs. Because these systems are both organized and later activated by hormones, the brain and vagina may be valuable model systems to st

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Herrera, Amparo, Javier Pineda, and María Teresa Antonio. "Toxic effects of perinatal arsenic exposure on the brain of developing rats and the beneficial role of natural antioxidants." Environmental Toxicology and Pharmacology 36, no. 1 (2013): 73–79. http://dx.doi.org/10.1016/j.etap.2013.03.018.

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Ulluwishewa, Rohana. "Spirituality, Universal Love and Sustainable Behaviour." Annals of Behavioral Neuroscience 1, no. 1 (2018): 66–76. http://dx.doi.org/10.18314/abne.v1i1.1240.

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Sustainability is a hot topic widely discussed in many circles of academics, professionals and policy makers worldwide. Technological, institutional and infrastructural changes are often considered to be effective measures in achieving sustainability goals. No doubt all such external changes are necessary; however, they remain inadequate without inner changes that make individual behaviour sustainable. This study points out that the root causes of our unsustainable behaviour is our perceived separateness from fellow human beings and the natural environment, which results in self-centeredness,

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Bukowska, Marta, Anna Bogacz, Marlena Wolek, et al. "Impact of Curcuma longa extract on the expression level of brain transporters in in vivo model." Herba Polonica 65, no. 1 (2019): 32–39. http://dx.doi.org/10.2478/hepo-2019-0005.

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Summary Introduction: Blood brain barrier and multidrug resistance phenomenon are subjects of many investigations. Mainly, because of their functions in protecting the central nervous system (CNS) by blocking the delivery of toxic substances to the brain. This special function has some disadvantages, like drug delivery to the brain in neurodegenerative diseases Objective: The aim of this study was to examine how natural and synthetic substances affect the expression levels of genes (Mdr1a, Mdr1b, Mrp1, Mrp2, Oatp1a4, Oatp1a5 and Oatp1c1) that encode transporters in the blood-brain barrier. Met

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Dou, Yan, and Dongju Zhao. "Targeting Emerging Pathogenic Mechanisms by Natural Molecules as Potential Therapeutics for Neurodegenerative Diseases." Pharmaceutics 14, no. 11 (2022): 2287. http://dx.doi.org/10.3390/pharmaceutics14112287.

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Natural molecules with favorable safety profile and broad pharmacological activities have shown great promise in the treatment of various neurodegenerative diseases (NDDs). Current studies applying natural molecules against NDDs mainly focus on well-recognized conventional pathogenesis, such as toxic protein aggregation, oxidative stress, and neuroinflammation. However, accumulating evidence reveals that some underlying pathogenic mechanisms are involved earlier and more deeply in the occurrence and development of NDDs, such as ferroptosis, energy metabolism disorders, autophagy-lysosomal dysf

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Iryna, MAIDANIUK, TSOI Tetiana, HOIAN Ihor, DOICHYK Maksym, PATLAICHUK Oksana, and STUPAK Olga. "The Problem of Artificial Intelligence in Contemporary Philosophy." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 13, no. 4 (2025): 436–49. https://doi.org/10.18662/brain/13.4/397.

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The importance of the topic of the article is due to the fact that nowadays there is a need to understand that the creation of artificial intelligence is associated with the understanding and study of natural intelligence. The problem of defining artificial intelligence is largely reduced to defining intelligence in general: is intelligence monolithic or does this concept define a set of different abilities? To what extent intelligence can be created? Is it possible to create computers with intelligence? These and other questions have not yet been answered by

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Dardevet, Lucie, Feten Najlaoui, Sonia Aroui, et al. "A Conjugate between Lqh-8/6, a Natural Peptide Analogue of Chlorotoxin, and Doxorubicin Efficiently Induces Glioma Cell Death." Biomedicines 10, no. 10 (2022): 2605. http://dx.doi.org/10.3390/biomedicines10102605.

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Natural peptides isolated from animal venoms generally target cell surface receptors with high affinity and selectivity. On many occasions, some of these receptors are over-expressed in cancer cells. Herein, we identified Lqh-8/6 as a natural peptide analog of chlorotoxin, a proven and useful compound for the diagnosis and treatment of glioma. Lqh-8/6 and two other natural analogues were chemically synthesized for the first time and evaluated for their ability to label, detect and prevent glioma growth in vitro. We demonstrate that a biotinylated version of Lqh-8/6 allows both the labeling of

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Flurie, Maurice, Zachary Cline, Anne Marie Morse, et al. "1036 Beyond Brain Fog: A Social Listening Analysis of Impaired Cognitive Functioning in Sleep Disorders." SLEEP 47, Supplement_1 (2024): A445—A446. http://dx.doi.org/10.1093/sleep/zsae067.01036.

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Abstract Introduction To best support a rare-disease community, it is imperative to understand the unique symptoms and challenges associated with their condition. In recent years, the experience of “brain fog” has been discussed across sleep-disorder communities, including narcolepsy and idiopathic hypersomnia (IH); however, the term “brain fog” is a vague descriptor that might represent several experiences. Here, we explored experiences with brain fog across sleep communities. The primary goal was to identify cognitive challenges associated with brain fog. Impacts on daily living were also ch

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Folarin, Oluwabusuyi Rachael, Funmilayo E. Olopade, and James Olukayode Olopade. "Essential Metals in the Brain and the Application of Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry for their Detection." Nigerian Journal of Physiological Sciences 36, no. 2 (2021): 123–47. http://dx.doi.org/10.54548/nigerjphysiolsci.v36i2.1.

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Metals are natural component of the ecosystem present throughout the layers of atmosphere; their abundant expression in the brain indicates their importance in the central nervous system (CNS). Within the brain tissue, their distribution is highly compartmentalized, the pattern of which is determined by their primary roles. Bio-imaging of the brain to reveal spatial distribution of metals within specific regions has provided a unique understanding of brain biochemistry and architecture, linking both the structures and the functions through several metal mediated activities. Bioavailability of

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Folarin, Oluwabusuyi Rachael, Funmilayo E. Olopade, and James Olukayode Olopade. "Essential Metals in the Brain and the Application of Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry for their Detection." Nigerian Journal of Physiological Sciences 36, no. 2 (2021): 123–47. http://dx.doi.org/10.54548/njps.v36i2.1.

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Metals are natural component of the ecosystem present throughout the layers of atmosphere; their abundant expression in the brain indicates their importance in the central nervous system (CNS). Within the brain tissue, their distribution is highly compartmentalized, the pattern of which is determined by their primary roles. Bio-imaging of the brain to reveal spatial distribution of metals within specific regions has provided a unique understanding of brain biochemistry and architecture, linking both the structures and the functions through several metal mediated activities. Bioavailability of

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