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Articles de revues sur le sujet « OAE3 »

Auteur : Grafiati

Publié le 9 mars 2023

Mis à jour le 19 juillet 2025

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1

Liu, Kaiyu. "Upper Cretaceous sequence stratigraphy, sea-level fluctuations and Oceanic Anoxic Events 2 and 3, Northeastern Gulf of Mexico." Stratigraphy 2, no. 2 (2005): 147–66. http://dx.doi.org/10.29041/strat.02.2.03.

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The relationship between Oceanic Anoxic Events (OAEs) and sea-level fluctuations can be determined by placing OAE sediments into an integrated sequence stratigraphic framework based on biostratigraphic age control, and regional seismic and well-log data. Two Upper Cretaceous black shale units in the northeastern Gulf of Mexico area, the Marine Tuscaloosa shale and the downdip Eutaw shale, are interpreted to be deposited in association with Late Cretaceous OAE 2 (Cenomanian–Turonian boundary event) and OAE3 (late Coniacian – early Santonian). TheMarine Tuscaloosa shale accumulated during the ma

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Ismail, Ahmed Aly. "A New Epistemological Insight of the Coniacian-Santonian Oceanic Anoxic Event (OAE3)." American Journal of BioScience 12, no. 1 (2024): 22–34. http://dx.doi.org/10.11648/j.ajbio.20241201.14.

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Eighteen planktic and eleven benthic foraminiferal species were recorded from the dark grey to black shale facies of the Matulla Formation in Abu Zeneima area, West-Central Sinai, Egypt. The faunal assemblage is dominated by cosmopolitan whiteinellids, marginotruncanids, Dicarinellids, Contusotruncanids and Heterohelicids. The planktic species with high taxonomic diversity were used to zone the Coniacian and Santonian stages, as well as define the Coniacian/ Santonian boundary, while benthic foraminifera is of minor contribution in age assignment. The stratigraphic analysis of the relations an

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Topper, R. P. M., J. Trabucho Alexandre, E. Tuenter, and P. Th Meijer. "A regional ocean circulation model for the mid-Cretaceous North Atlantic Basin: implications for black shale formation." Climate of the Past 7, no. 1 (2011): 277–97. http://dx.doi.org/10.5194/cp-7-277-2011.

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Abstract. High concentrations of organic matter accumulated in marine sediments during Oceanic Anoxic Events (OAEs) in the Cretaceous. Model studies examining these events invariably make use of global ocean circulation models. In this study, a regional model for the North Atlantic Basin during OAE2 at the Cenomanian-Turonian boundary has been developed. A first order check of the results has been performed by comparison with the results of a recent global Cenomanian CCSM3 run, from which boundary and initial conditions were obtained. The regional model is able to maintain tracer patterns and

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Topper, R. P. M., J. Trabucho Alexandre, E. Tuenter, and P. Th Meijer. "A regional ocean circulation model for the mid-Cretaceous North Atlantic Basin: implications for black shale formation." Climate of the Past Discussions 6, no. 5 (2010): 2371–421. http://dx.doi.org/10.5194/cpd-6-2371-2010.

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Abstract. High concentrations of organic matter accumulated in marine sediments during Oceanic Anoxic Events (OAEs) in the Cretaceous. Model studies examining these events invariably make use of global ocean circulation models. In this study, a regional model for the North Atlantic Basin during OAE2 at the Cenomanian-Turonian boundary is developed. A first order check of the results is performed by comparison with the results of a recent global Cenomanian CCSM3 run from which boundary and initial conditions were obtained. The regional model is able to maintain tracer patterns and to produce ve

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Freymueller, Nicholas A., Jason R. Moore, and Corinne E. Myers. "An analysis of the impacts of Cretaceous oceanic anoxic events on global molluscan diversity dynamics." Paleobiology 45, no. 02 (2019): 280–95. http://dx.doi.org/10.1017/pab.2019.10.

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AbstractOceanic anoxic events (OAEs) are contemporaneous with 11 of the 18 largest Phanerozoic extinction events, but the magnitude and selectivity of their paleoecological impact remains disputed. OAEs are associated with abrupt, rapid warming and increased CO2flux to the atmosphere; thus, insights from this study may clarify the impact of current anthropogenic climate change on the biosphere. We investigated the influence of the Late Cretaceous Bonarelli event (OAE2; Cenomanian/Turonian stage boundary; ~94 Ma) on generic- and species-level molluscan diversity, extinction rates, and ecologica

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Aradhana, Aparna, Gadadhar Sarangi, Prasant Saboth, and Radha Tripathy. "Assessment of Hearing Impairment in NICU Graduates by Otoacoustic Emission and Brainstem Evoked Response Audiometry Tests." Journal of Neonatology 34, no. 3 (2020): 109–17. http://dx.doi.org/10.1177/0973217920951878.

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Objectives: To find out the incidence of hearing impairment in Neonatal Intensive Care Unit (NICU)-admitted newborns and to correlate between several risk factors. Design: Prospective observational study. Setting: In a tertiary teaching hospital of Odisha between October 2014 and October 2016. Study population: 100 newborns delivered in the institution and admitted in NICU with usual indications and risk factors that underwent otoacoustic emission 1 and 2 (OAE1, OAE2) and Brainstem Evoked Response Audiometry (BERA). Results: 84 babies in OAE1 and 86 babies in OAE2 got “pass” results. In BERA t

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Karakitsios, V., H. Tsikos, K. Agiadi - Katsiaouni, S. Dermitzoglou, and E. Chatziharalambous. "THE USE OF CARBON AND OXYGEN STABLE ISOTOPES IN THE STUDY OF GLOBAL PALAEOCEANOGRAPHIC CHANGES: EXAMPLES FROM THE CRETACEOUS SEDIMENT ROCKS OF WESTERN GREECE." Bulletin of the Geological Society of Greece 39, no. 1 (2006): 64. http://dx.doi.org/10.12681/bgsg.18445.

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In the present paper we examine the use of carbon and oxygen stable isotopes in the study of global palaeoceanographic changes, with special reference to the oceanic anoxic events (OAEs). The analysis of stable isotopes was applied to the examination of Cretaceous sediments from the Ionian and Pindos zones of Western Greece. In the Ionian zone the carbon and oxygen stable isotopes, combined with biostratigraphic data, record the palaeoenvironmental change corresponding to the anoxic events Bonarelli (Cenomanian/Turonian, OAE2) and Paquier (Lower Albian, OAE1b). In the Pindos zone, within the C

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Machado, M. C., F. Chemale, K. Kawashita, O. Rey, and C. A. V. Moura. "Isotope studies of carbonate rocks of La Luna Formation (Venezuela) to constrain the oceanic anoxic event 3 (OAE3)." Journal of South American Earth Sciences 72 (December 2016): 38–48. http://dx.doi.org/10.1016/j.jsames.2016.07.001.

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Lowery, Christopher M., R. Mark Leckie, and Bradley B. Sageman. "Micropaleontological evidence for redox changes in the OAE3 interval of the US Western Interior: Global vs. local processes." Cretaceous Research 69 (January 2017): 34–48. http://dx.doi.org/10.1016/j.cretres.2016.08.011.

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Abdala, Carolina, Tricia Benjamin, Samantha Stiepan, Ping Luo, and Christopher A. Shera. "Detection of mild sensory hearing loss using a joint reflection-distortion otoacoustic emission profile." Journal of the Acoustical Society of America 156, no. 4 (2024): 2220–36. http://dx.doi.org/10.1121/10.0030399.

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Measuring and analyzing both nonlinear-distortion and linear-reflection otoacoustic emissions (OAEs) combined creates what we have termed a “joint-OAE profile.” Here, we test whether these two classes of emissions have different sensitivities to hearing loss and whether our joint-OAE profile can detect mild-moderate hearing loss better than conventional OAE protocols have. 2f1-f2 distortion-product OAEs and stimulus-frequency OAEs were evoked with rapidly sweeping tones in 300 normal and impaired ears. Metrics included OAE amplitude for fixed-level stimuli as well as slope and compression feat

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Hauser, Samantha, Michael G. Heinz, and Hari Bharadwaj. "Cross-species characterization of joint otoacoustic emission profiles in sensorineural hearing loss." Journal of the Acoustical Society of America 153, no. 3_supplement (2023): A161. http://dx.doi.org/10.1121/10.0018513.

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Current clinical assessment of otoacoustic emissions (OAEs) is typically limited to presence or absence of emissions to detect hearing loss, but recent work suggests advanced analyses and data collection methods have the potential to improve the diagnostic utility of OAEs. OAEs arise from two distinct mechanisms, nonlinear distortion and linear reflection, which are both sensitive to the health of outer hair cells but may reflect separate aspects of cochlear mechanical function. Joint distortion-reflection OAE profiles offer a non-invasive characterization of peripheral auditory physiology and

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Mishra, Srikanta K., and Michelle Hernandez. "Temporal Features of Otoacoustic Emissions." Perspectives of the ASHA Special Interest Groups 2, no. 2 (2017): 169–75. http://dx.doi.org/10.1044/persp2.sig2.169.

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The true power of otoacoustic emissions (OAEs) continues to be explored. OAE spectral characteristics are typically studied in research and applied in the clinic. However, OAE temporal aspects are relatively underexplored. Not using temporal features is similar to ignoring nearly half of the information that OAEs provide. Besides providing information related to the generation of OAEs and cochlear mechanics, the temporal characteristics have important clinical implications, such as for assessing frequency selectivity, characterizing the strength of the efferent auditory system. This review pro

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Singh, Abha, and Prem Raj Uddandam. "Mesozoic Oceanic Anoxic Events: Records from India and future scope." Journal of Palaeosciences 73, no. 2 (2024): 99–118. https://doi.org/10.54991/jop.2024.1888.

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This paper presents a review of the Mesozoic Oceanic Anoxic Event (OAE) studies, carried out from India. It also provides a summary of the researches pursued on biostratigraphic, isotopic, and organic geochemical proxies for establishing Oceanic Anoxic Events (OAEs) from the Mesozoic sedimentary sequences of the Indian Subcontinent. From Indian sedimentary basins, studies are available on OAE-1a, OAE-1b, OAE-1d, OAE-2, and OAE-3. From the Cauvery Basin records of OAE-1b, OAE-1d, OAE-2, and OAE-3 are available. From the Spiti Valley records are present on OAE-2 (Chikkim Formation) only, and the

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Rey, O., J. A. Simo (Toni), and M. A. Lorente. "A record of long- and short-term environmental and climatic change during OAE3: La Luna Formation, Late Cretaceous (Santonian–early Campanian), Venezuela." Sedimentary Geology 170, no. 1-2 (2004): 85–105. http://dx.doi.org/10.1016/j.sedgeo.2004.06.006.

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Beil, Sebastian, Wolfgang Kuhnt, Ann Holbourn, et al. "Cretaceous oceanic anoxic events prolonged by phosphorus cycle feedbacks." Climate of the Past 16, no. 2 (2020): 757–82. http://dx.doi.org/10.5194/cp-16-757-2020.

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Abstract. Oceanic anoxic events (OAEs) document major perturbations of the global carbon cycle with repercussions for the Earth's climate and ocean circulation that are relevant to understanding future climate trends. Here, we compare the onset and development of Cretaceous OAE1a and OAE2 in two drill cores with unusually high sedimentation rates from the Vocontian Basin (southern France) and Tarfaya Basin (southern Morocco). OAE1a and OAE2 exhibit remarkable similarities in the evolution of their carbon isotope (δ13C) records, with long-lasting negative excursions preceding the onset of the m

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Siedlecki, Tomasz, and Jakub Zielinski. "SPECTRAL KURTOSIS OF OTOACOUSTIC EMISSIONS USING THE HUSIMI TRANSFORM: A PILOT STUDY." Journal of Hearing Science 5, no. 4 (2015): 15–25. http://dx.doi.org/10.17430/896155.

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BackgroundTime-frequency distributions can help reveal resonant modes of OAEs. The Husimi transform is the time-frequency distribution of probability. The sound pressure probability density function for a given frequency can be derived from the Husimi transform. Using the Husimi transform as the weight function, it is possible to define the spectral kurtosis of OAEs.Material and MethodsThe Husimi transform was calculated numerically from OAE data recorded from subjects with normal hearing. We examined click-evoked OAEs (CEOAEs) and tone-burst-evoked OAEs (TBOAEs) with stimuli centered at 1, 2,

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Venancio, Igor M., Thiago P. Santos, Fellippe R. A. Bione, et al. "Preservation Factors during Cretaceous Oceanic Anoxic Events in the Espírito Santo Basin, Southeast Brazil." Geosciences 12, no. 10 (2022): 351. http://dx.doi.org/10.3390/geosciences12100351.

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The oceanic anoxic events (OAEs) are characterized by enhanced accumulation of organic matter in marine sediments. However, there is still an ongoing debate regarding the interplay between production and preservation during these events. Moreover, few studies provide quantitative estimations of primary productivity and/or the amount of carbon preserved during the OAEs. Here, we used geochemical data from multiple wells located at the Espírito Santo Basin that cover the intervals of events OAE1d and OAE2 to provide quantitative estimates of preservation factors. Our results show enhanced preser

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Lewis, James D. "Model-based prediction of otoacoustic emission level, noise level, and signal-to-noise ratio during time-synchronous averaging." Journal of the Acoustical Society of America 154, no. 2 (2023): 709–20. http://dx.doi.org/10.1121/10.0020568.

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Although averaging is effective in reducing noise, its efficiency rapidly decreases beyond several hundred averages. Depending on environmental and patient noise levels, several hundred averages may be insufficient for informed clinical decision making. The predictable nature of the otoacoustic emission (OAE) and noise during time-synchronous averaging implicates the use of predictive modeling as an alternative to increased averaging when noise is high. Click-evoked OAEs were measured in 98, normal-hearing subjects. Average OAE and noise levels were calculated for subsets of the total number o

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Bower, Charles M., and Patti F. Martin. "Universal Pediatric Hearing Screening." Otolaryngology–Head and Neck Surgery 112, no. 5 (1995): P149. http://dx.doi.org/10.1016/s0194-5998(05)80392-4.

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Nadon, Vincent, Annelies Bockstael, Dick Botteldooren, and Jérémie Voix. "Field Monitoring of Otoacoustic Emissions During Noise Exposure: Pilot Study in Controlled Environment." American Journal of Audiology 26, no. 3S (2017): 352–68. http://dx.doi.org/10.1044/2017_aja-17-0003.

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Purpose In spite of all the efforts to implement workplace hearing conservation programs, noise-induced hearing loss remains the leading cause of disability for North American workers. Nonetheless, an individual's susceptibility to noise-induced hearing loss can be estimated by monitoring changes in hearing status in relation to the level of ambient noise exposure. The purpose of this study was to validate an approach that could improve workplace hearing conservation practices. The approach was developed using a portable and robust system designed for noisy environments and consisted of taking

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Papsin, Emily, Adrienne L. Harrison, Mattia Carraro, and Robert V. Harrison. "Contralateral Ear Occlusion for Improving the Reliability of Otoacoustic Emission Screening Tests." International Journal of Otolaryngology 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/248187.

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Newborn hearing screening is an established healthcare standard in many countries and testing is feasible using otoacoustic emission (OAE) recording. It is well documented that OAEs can be suppressed by acoustic stimulation of the ear contralateral to the test ear. In clinical otoacoustic emission testing carried out in a sound attenuating booth, ambient noise levels are low such that the efferent system is not activated. However in newborn hearing screening, OAEs are often recorded in hospital or clinic environments, where ambient noise levels can be 60–70 dB SPL. Thus, results in the test ea

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Sachse, V. F., S. Heim, H. Jabour, et al. "Organic geochemical characterization of Santonian to Early Campanian organic matter-rich marls (Sondage No. 1 cores) as related to OAE3 from the Tarfaya Basin, Morocco." Marine and Petroleum Geology 56 (September 2014): 290–304. http://dx.doi.org/10.1016/j.marpetgeo.2014.02.004.

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Bergevin, Christopher, Geoffrey A. Manley, and Christine Köppl. "Salient features of otoacoustic emissions are common across tetrapod groups and suggest shared properties of generation mechanisms." Proceedings of the National Academy of Sciences 112, no. 11 (2015): 3362–67. http://dx.doi.org/10.1073/pnas.1418569112.

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Otoacoustic emissions (OAEs) are faint sounds generated by healthy inner ears that provide a window into the study of auditory mechanics. All vertebrate classes exhibit OAEs to varying degrees, yet the biophysical origins are still not well understood. Here, we analyzed both spontaneous (SOAE) and stimulus-frequency (SFOAE) otoacoustic emissions from a bird (barn owl, Tyto alba) and a lizard (green anole, Anolis carolinensis). These species possess highly disparate macromorphologies of the inner ear relative to each other and to mammals, thereby allowing for novel insights into the biomechanic

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Nicholas, Sarah, Joseph Kei, Gail Woodyatt, and Bradley McPherson. "Otoacoustic Emission Findings in Rett Syndrome." Journal of the American Academy of Audiology 10, no. 08 (1999): 436–44. http://dx.doi.org/10.1055/s-0042-1748517.

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AbstractRett syndrome is a neurologic disorder affecting mainly females after a seemingly normal 6 to 18 months of life. The resulting developmental disabilities include apparent dementia and loss of acquired language, social skills, and purposeful hand use. The present investigation assessed 10 individuals with Rett syndrome and a control group matched for age and sex. The present study aimed to determine the clinical feasibility of obtaining otoacoustic emissions (OAEs) from the Rett syndrome group and to compare the characteristics of the transient evoked and distortion-product OAEs obtaine

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Baldwin, Stacey M., Byron J. Gajewski, and Judith E. Widen. "An Evaluation of the Cross-Check Principle Using Visual Reinforcement Audiometry, Otoacoustic Emissions, and Tympanometry." Journal of the American Academy of Audiology 21, no. 03 (2010): 187–96. http://dx.doi.org/10.3766/jaaa.21.3.7.

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Background: Early intervention to reduce the effects of congenital hearing loss requires accurate description of hearing loss. In pediatric audiology, a cross-check principle is used to compare behavioral and physiological tests. Purpose: The purpose of this study was to investigate the correspondence of visual reinforcement audiometry (VRA) minimal response levels (MRLs), otoacoustic emissions (OAEs), tympanometry, and VRA test reliability to determine the odds of obtaining the expected cross-check results. We hypothesized that (1) when MRLs were within normal limits (WNL), OAEs would be pres

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Prauss, M. L. "Marine palynology of the Oceanic Anoxic Event 3 (OAE3, Coniacian – Santonian) at Tarfaya, Morocco, NW Africa – transition from preservation to production controlled accumulation of marine organic carbon." Cretaceous Research 53 (March 2015): 19–37. http://dx.doi.org/10.1016/j.cretres.2014.10.005.

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Crouwel, Femke, M. Meurs-Szojda, M. Klemt-Kropp, P. Fockens, and M. Grasman. "The diagnostic yield of open-access endoscopy of the upper gastrointestinal tract in the Netherlands." Endoscopy International Open 06, no. 04 (2018): E383—E394. http://dx.doi.org/10.1055/s-0043-123185.

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Abstract Background and study aims Since the introduction of open-access esophago-gastroduodenoscopy (OAE) there is an increase in the total number of performed OAEs whilst the frequency of clinical relevant findings has decreased. The aim of this study was to assess the appropriate use and the diagnostic yield of OAE in the Netherlands and to determine which patient variables are able to predict a malignant finding. Patients and methods A retrospective chart review of all referrals for diagnostic OAE between October 2012 and October 2016 at the Northwest Clinics was performed. The indications

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Gorga, Michael P., Kimberly Preissler, Jeff Simmons, Lisa Walker, and Brenda Hoover. "Some Issues Relevant to Establishing a Universal Newborn Hearing Screening Program." Journal of the American Academy of Audiology 12, no. 02 (2001): 101–12. http://dx.doi.org/10.1055/s-0042-1745585.

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AbstractThis article describes some of the factors relevant to the establishment of a universal newborn hearing screening (UNHS) program. First, the difficulty in providing precise estimates of test sensitivity and specificity are reviewed. This section is followed by hypothetical estimates of overall programmatic costs, first for a fixed number of babies to be screened and then as a function of the number of babies to be screened in a year. Included in these estimates are the costs for equipment, disposables, personnel, and follow-up testing. These estimates are provided for three different s

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Chawla, Deeksha, Rohit Verma, Siddharth Bhargava, Manish Munjal, Anshuman Dhawan, and Udeyana Singh. "Screening for Hearing Loss in High-Risk Neonates Using Otoacoustic Emissions." Indian Journal of Otology 29, no. 2 (2023): 101–4. http://dx.doi.org/10.4103/indianjotol.indianjotol_55_23.

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Context: The development and maturation of the hearing process begin in the fetal stage and progresses up to 6 months of age. Neonatal screening is therefore an essential method to screen for hearing loss at an early age. As there is a paucity of literature on the use of otoacoustic emissions (OAEs) and brainstem evoked response (BERA) tests for screening, hence we conducted a prospective observational study to screen the high-risk neonates admitted to neonatal intensive care unit (NICU) using OAE and further BERA (wherever indicated). Aims: The primary objective was to estimate the incidence

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S., Gangadhara K., Amrutha V. Bhat, and Sridhara S. "Application of otoacoustic emissions and brainstem evoked response audiometry in newborn hearing screening." International Journal of Otorhinolaryngology and Head and Neck Surgery 8, no. 1 (2021): 26. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20214895.

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<p class="abstract"><strong>Background: </strong>Newborn hearing screening was conducted in a tertiary care hospital in a step by step manner using otoacoustic emissions (OAE) and brainstem evoked response audiometry (BERA) and details were recorded.</p><p class="abstract"><strong>Methods:</strong> A prospective institutional based study was conducted. All the newborns born in the hospital over a period of 18 months from December 2018 to May 2020 were considered in the study. Healthy newborns were screened bedside within 24 hours of delivery and NICU (

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Hall, James W., Jane E. Baer, Patricia A. Chase, and Mitchell K. Schwaber. "Clinical Application of Otoacoustic Emissions: What do we Know about Factors Influencing Measurement and Analysis?" Otolaryngology–Head and Neck Surgery 110, no. 1 (1994): 22–38. http://dx.doi.org/10.1177/019459989411000103.

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Three electrophysiologic audiologic procedures-aural immittance measurement, auditory brainstem response (ABR), and otoacoustic emissions (OAE) — were first described in the 1970's. Immittance measurement and ABR have contributed importantly for years to the assessment of auditory function in children and adults, whereas OAEs have not yet been incorporated into the everyday audiology test battery. In this article, we argue that the transition from OAE measurement by hearing scientists in laboratory settings to routine application by audiologists in the clinic will be greatly facilitated by (1)

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Jedrzejczak, W. Wiktor, Elżbieta Gos, Edyta Pilka, Piotr H. Skarzynski, Henryk Skarzynski, and Stavros Hatzopoulos. "Pitfalls in the Detection of Hearing Loss via Otoacoustic Emissions." Applied Sciences 11, no. 5 (2021): 2184. http://dx.doi.org/10.3390/app11052184.

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Otoacoustic emissions (OAEs) are currently used as a valuable audiological test or as a hearing screening tool. There are many commercially available OAE recording systems that are used both for clinical practice and for research. However, there is little information in the literature comparing their performance in detecting hearing loss. The purpose of this prospective, nonrandomized, and controlled study was to evaluate the screening performance obtained from recent and older versions of the Otometrics Accuscreen OAE screening device in comparison with the Otodynamics ILO-292 OAE system, whi

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Terpos, Evangelos, Maria Gavriatopoulou, Ioannis Ntanasis-Stathopoulos, et al. "Less Is More: Deciphering the Association between Ocular Adverse Events and Clinical Activity of Belantamab Mafodotin in Multiple Myeloma." Blood 144, Supplement 1 (2024): 3380. https://doi.org/10.1182/blood-2024-209915.

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Introduction Belantamab mafodotin (belamaf; GSK2857916) has demonstrated important efficacy and tolerability in patients (pts) with relapsed/refractory multiple myeloma (MM). Ocular adverse events (OAEs; best corrected visual acuity [BCVA] change from baseline and keratopathy) are the most common adverse events (AEs) observed with belamaf and the main reason for dose holds and delays. However, the effect of OAE-related dose modifications on treatment efficacy has not been investigated. Herein, we present data from the BelaRd study, evaluating belamaf plus lenalidomide/dexamethasone (Rd) in tra

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Shera, Christopher. "The sing-song of old man human ear." Journal of the Acoustical Society of America 155, no. 3_Supplement (2024): A218. http://dx.doi.org/10.1121/10.0027357.

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Otoacoustic emissions evoked from the inner ear are the barely audible, signature by-product of the delicate hydromechanical amplifier that evolved within its bony walls. Compared to the sounds evoked from the ears of common laboratory animals, otoacoustic emissions (OAEs) from human ears have exceptionally long delays, typically exceeding those of cats, guinea pigs, and chinchillas by a factor of two to three. This presentation asks “Why are human OAE delays so long?” and reviews efforts to find answers in the mechanical frequency selectivity of the inner ear. The road to understanding specie

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Jedrzejczak, W. Wiktor, Rafal Milner, Malgorzata Ganc, Edyta Pilka, and Henryk Skarzynski. "No Change in Medial Olivocochlear Efferent Activity during an Auditory or Visual Task: Dual Evidence from Otoacoustic Emissions and Event-Related Potentials." Brain Sciences 10, no. 11 (2020): 894. http://dx.doi.org/10.3390/brainsci10110894.

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The medial olivocochlear (MOC) system is thought to be responsible for modulation of peripheral hearing through descending (efferent) pathways. This study investigated the connection between peripheral hearing function and conscious attention during two different modality tasks, auditory and visual. Peripheral hearing function was evaluated by analyzing the amount of suppression of otoacoustic emissions (OAEs) by contralateral acoustic stimulation (CAS), a well-known effect of the MOC. Simultaneously, attention was evaluated by event-related potentials (ERPs). Although the ERPs showed clear di

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Prawanta, Ekkanat, Munhum Park, and Yuttana Roongthumskul. "Head-related transfer function for the measurements of otoacoustic emissions evoked by localized sound sources." Journal of Physics: Conference Series 2934, no. 1 (2025): 012031. https://doi.org/10.1088/1742-6596/2934/1/012031.

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Abstract Not one but two ears enable us to identify the location of a sound source by comparing the amplitudes and phases of acoustic signals. In this study, we explore the response of the inner ears to localized sounds by measuring otoacoustic emissions (OAEs) which refers to sounds produced by the inner ear in response to external sounds, thus governed by the activities of the acoustic receptors. OAEs were recorded simultaneously from both ears by fitting a small microphone-speaker probe into each ear canal. The binaural sounds used to evoke OAEs were designed to correspond to a localized so

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CORS, JEAN, ULRICH HEIMHOFER, THIERRY ADATTE, PETER A. HOCHULI, STEFAN HUCK, and TELM BOVER-ARNAL. "Climatic evolution across oceanic anoxic event 1a derived from terrestrial palynology and clay minerals (Maestrat Basin, Spain)." Geological Magazine 152, no. 4 (2014): 632–47. http://dx.doi.org/10.1017/s0016756814000557.

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AbstractStudies dealing with the response of the continental biosphere to the environmental perturbations associated with Cretaceous oceanic anoxic events (OAEs) are comparatively rare. Here, a quantitative spore-pollen record combined with clay mineral data is presented, which covers the entire early Aptian OAE 1a interval (Forcall Formation, Maestrat basin, east Spain). The well-expressed OAE 1a carbon-isotope anomaly is paralleled by changes in the clay mineral assemblage and by a stepwise decline in the normalized frequency ofClassopollispollen (produced by xerophytic Cheirolepidiaceae) wi

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Bu, Xingkuan, Xiaolu Li, and Carlie Driscoll. "The Chinese Hearing Questionnaire for School Children." Journal of the American Academy of Audiology 16, no. 09 (2005): 687–97. http://dx.doi.org/10.3766/jaaa.16.9.6.

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Hearing loss is the most common of all disabilities in China, with three million of the 1.4 billion population affected. Recently, the release of an official neonatal hearing screening consensus has drawn attention to the importance of continued surveillance throughout childhood and the need for a system that is suited to the Chinese situation. The current research aimed to develop and evaluate a questionnaire for mass screening of school children in China. In Jiangsu Province, 317 rural students were screened using the Chinese Hearing Questionnaire for School Children (CHQS) and otoacoustic e

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Ruvalcaba Baroni, I., R. P. M. Topper, N. A. G. M. van Helmond, H. Brinkhuis, and C. P. Slomp. "Biogeochemistry of the North Atlantic during oceanic anoxic event 2: role of changes in ocean circulation and phosphorus input." Biogeosciences 11, no. 4 (2014): 977–93. http://dx.doi.org/10.5194/bg-11-977-2014.

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Abstract. The geological record provides evidence for the periodic occurrence of water column anoxia and formation of organic-rich deposits in the North Atlantic Ocean during the mid-Cretaceous (hereafter called the proto-North Atlantic). Both changes in primary productivity and oceanic circulation likely played a role in the development of the low-oxygen conditions. Several studies suggest that an increased input of phosphorus from land initiated oceanic anoxic events (OAEs). Other proposed mechanisms invoke a vigorous upwelling system and an ocean circulation pattern that acted as a trap for

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Ruvalcaba-Baroni, I., R. P. M. Topper, N. A. G. M. van Helmond, H. Brinkhuis, and C. P. Slomp. "Was the North Atlantic Ocean well-ventilated during Oceanic Anoxic Event 2 in the mid-Cretaceous?" Biogeosciences Discussions 10, no. 8 (2013): 13231–76. http://dx.doi.org/10.5194/bgd-10-13231-2013.

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Abstract. The geological record provides evidence for the periodic occurrence of water column anoxia and formation of organic-rich deposits in the North Atlantic Ocean during the mid-Cretaceous (hereafter called proto-North Atlantic). Both changes in primary productivity and oceanic circulation likely played a role in the development of the low oxygen conditions. Several studies suggest that an increased input of phosphorus from land initiated oceanic anoxic events (OAEs). Other proposed mechanisms invoke a vigorous upwelling system and an ocean circulation pattern that acted as a trap for nut

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De Groote, Evelien, Annelies Bockstael, Dick Botteldooren, Patrick Santens, and Miet De Letter. "The Effect of Parkinson's Disease on Otoacoustic Emissions and Efferent Suppression of Transient Evoked Otoacoustic Emissions." Journal of Speech, Language, and Hearing Research 64, no. 4 (2021): 1354–68. http://dx.doi.org/10.1044/2020_jslhr-20-00594.

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Purpose Several studies have demonstrated increased auditory thresholds in patients with Parkinson's disease (PD) based on subjective tonal audiometry. However, the pathophysiological mechanisms underlying auditory dysfunction in PD remain elusive. The primary aim of this study was to investigate cochlear and olivocochlear function in PD using objective measurements and to assess the effect of dopaminergic medication on auditory function. Method Eighteen patients with PD and 18 gender- and age-matched healthy controls (HCs) were included. Patients with PD participated in medication on and off

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Beksac, Meral, Hang Quach, Vania Hungria, et al. "Baseline ocular conditions and risk of ocular events in patients (pts) with relapsed/refractory multiple myeloma (RRMM) from the DREAMM-7 and DREAMM-8 trials of belantamab mafodotin (belamaf)." Journal of Clinical Oncology 43, no. 16_suppl (2025): 7544. https://doi.org/10.1200/jco.2025.43.16_suppl.7544.

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7544 Background: Belamaf combinations were evaluated for RRMM in the phase 3 DREAMM-7 (belamaf + bortezomib + dexamethasone [BVd]; NCT04246047) and DREAMM-8 (belamaf + pomalidomide + dexamethasone [BPd]; NCT04484623) trials, and significant progression-free survival benefits were reported over standard of care, with significant overall survival benefit reported for BVd. Ocular events (e.g., ocular adverse events [oAEs], blurred vision, dry eye) occurred with belamaf and most resolved with dose holds and modifications. We examined the baseline eye health of pts with RRMM receiving BVd or BPd, a

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Farhadi, Afagh, Samantha Hauser, Andrew Sivaprakasam, and Michael G. Heinz. "Evaluation of efferent influences on neural coding using pre-clinical models of sensorineural hearing loss." Journal of the Acoustical Society of America 155, no. 3_Supplement (2024): A40. http://dx.doi.org/10.1121/10.0026729.

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The medial olivocochlear (MOC) efferent system is less explored than the ascending auditory pathway but likely contributes in important ways to neural coding and perception. These effects are thought to vary across stimulus configurations, anesthetic states, and subtypes of sensorineural hearing loss (SNHL). To explore effective assays of MOC effects on neural coding, we have recorded Interleaved otoacoustic emissions (OAEs) and envelope following responses (EFRs) from several pre-clinical SNHL chinchilla models. Our preliminary observations include increases in OAEs with inner-hair-cell loss

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Zimatore, Giovanna, Piotr Henryk Skarzynski, Federica Di Berardino, et al. "Re-evaluating the scoring criteria of the Interacoustics Sera Neonatal Hearing Screener." Hearing Balance and Communication 22, no. 3 (2024): 100–109. http://dx.doi.org/10.4103/hbc.hbc_24_24.

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Abstract Introduction: Newborn hearing screeners via otoacoustic emissions (OAEs) have become the standard in audiological clinical practice. Despite the application of OAE protocols for more than 3 decades, there has been no consensus on the standardization of the recorded responses. Usually, manufacturers based the scoring criteria of the OAE responses on small scale samples and in many cases on data published in the literature. Since there are no standards in the OAE probe construction, the resulted OAE responses are quite different between OAE screeners. The project evaluated the scoring c

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Spankovich, Christopher, Glenis R. Long, and Linda J. Hood. "Early Indices of Reduced Cochlear Function in Young Adults with Type-1 Diabetes Revealed by DPOAE Fine Structure." Journal of the American Academy of Audiology 30, no. 06 (2019): 459–71. http://dx.doi.org/10.3766/jaaa.17113.

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AbstractThe relationship between type-1 diabetes mellitus (DM) and cochlear dysfunction remains inconclusive.The purpose of this study was to examine otoacoustic emissions (OAEs) in normal-hearing young adults with type-1 DM as compared with matched controls and identify potential covariates influencing OAE findings.Cross-sectional study.N = 40 young adults aged 18–28 years including individuals with type-1 DM (n = 20) and age–gender matched controls (n = 20) with normal hearing sensitivity.Measures of pure-tone threshold sensitivity and OAEs, including distortion product otoacoustic emissions

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Friedrich, Oliver, Silke Voigt, Tanja Kuhnt, and Mirjam C. Koch. "Repeated bottom-water oxygenation during OAE 2: timing and duration of short-lived benthic foraminiferal repopulation events (Wunstorf, northern Germany)." Journal of Micropalaeontology 30, no. 2 (2011): 119–28. http://dx.doi.org/10.1144/0262-821x11-011.

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Abstract. Published proxy data for Oceanic Anoxic Event 2 (OAE 2 or Cenomanian–Turonian Boundary Event) and other mid-Cretaceous OAEs indicate widespread anoxic bottom-water conditions. However, increasing evidence shows that anoxia was not permanent but subject to significant fluctuations. We have generated X-ray fluorescence elemental concentration and benthic foraminiferal assemblage records for a short section of OAE 2 black shales from Wunstorf, northern Germany. Two intervals of low sulphur elemental concentration are interpreted as periods of increased oxygenation of bottom waters. This

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Them, Theodore R., Benjamin C. Gill, Andrew H. Caruthers, et al. "Thallium isotopes reveal protracted anoxia during the Toarcian (Early Jurassic) associated with volcanism, carbon burial, and mass extinction." Proceedings of the National Academy of Sciences 115, no. 26 (2018): 6596–601. http://dx.doi.org/10.1073/pnas.1803478115.

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For this study, we generated thallium (Tl) isotope records from two anoxic basins to track the earliest changes in global bottom water oxygen contents over the Toarcian Oceanic Anoxic Event (T-OAE; ∼183 Ma) of the Early Jurassic. The T-OAE, like other Mesozoic OAEs, has been interpreted as an expansion of marine oxygen depletion based on indirect methods such as organic-rich facies, carbon isotope excursions, and biological turnover. Our Tl isotope data, however, reveal explicit evidence for earlier global marine deoxygenation of ocean water, some 600 ka before the classically defined T-OAE. T

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De Keyser, Kim, Miet De Letter, Evelien De Groote, et al. "Systematic Audiological Assessment of Auditory Functioning in Patients With Parkinson's Disease." Journal of Speech, Language, and Hearing Research 62, no. 12 (2019): 4564–77. http://dx.doi.org/10.1044/2019_jslhr-h-19-0097.

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Purpose Alterations in primary auditory functioning have been reported in patients with Parkinson's disease (PD). Despite the current findings, the pathophysiological mechanisms underlying these alterations remain unclear, and the effect of dopaminergic medication on auditory functioning in PD has been explored insufficiently. Therefore, this study aimed to systematically investigate primary auditory functioning in patients with PD by using both subjective and objective audiological measurements. Method In this case–control study, 25 patients with PD and 25 age-, gender-, and education-matched

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Mazumder, Rajarshi, Samson Kamya Lubowa, Noriko Salamon, et al. "Comparison of Structural Changes in Nodding Syndrome and Other Epilepsies Associated WithOnchocerca volvulus." Neurology - Neuroimmunology Neuroinflammation 10, no. 2 (2022): e200074. http://dx.doi.org/10.1212/nxi.0000000000200074.

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Background and ObjectiveNodding syndrome (NS) is a unique childhood-onset epileptic disorder that occurs predominantly in several regions of sub-Saharan Africa. The disease has been associated withOnchocerca volvulus (Ov)–induced immune responses and possible cross-reactivity with host proteins. The aim of this study was to compare structural changes in the brain on MRI between NS and other forms of onchocerciasis-associated epilepsies (OAEs) and to relate structural changes to the Ov-induced immune responses and level of disability.MethodsThirty-nine children with NS and 14 age-matched partic

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Löhr, S. C., and M. J. Kennedy. "Organomineral nanocomposite carbon burial during Oceanic Anoxic Event 2." Biogeosciences Discussions 11, no. 5 (2014): 6815–44. http://dx.doi.org/10.5194/bgd-11-6815-2014.

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Abstract. Organic carbon (OC) enrichment in sediments deposited during Oceanic Anoxic Events (OAEs) is commonly attributed to elevated productivity and marine anoxia. We find that OC enrichment in the late Cenomanian aged OAE2 at Demerara Rise was controlled by co-occurrence of anoxic bottom-water, sufficient productivity to saturate available mineral surfaces and variable deposition of high surface area detrital smectite clay. Redox indicators show consistently oxygen-depleted conditions, while a strong correlation between OC concentration and sediment mineral surface area (R2=0.92) occurs ac

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