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Littérature scientifique sur le sujet « Penicillium rubens »

Auteur : Grafiati

Publié le 2 juin 2025

Mis à jour le 31 juillet 2025

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Articles de revues sur le sujet "Penicillium rubens"

Lalchhandama, Kholhring. "History of penicillin." WikiJournal of Medicine 8, no. 1 (2021): 3. http://dx.doi.org/10.15347/wjm/2021.003.

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The history of penicillin was shaped by the contributions of numerous scientists. The ultimate result was the discovery of the mould Penicillium's antibacterial activity and the subsequent development of penicillins, the most widely used antibiotics. Following an accidental discovery of the mould, later identified as Penicillium rubens, as the source of the antibacterial principle (1928) and the production of a pure compound (1942), penicillin became the first naturally derived antibiotic. There is anecdotal evidence of ancient societies using moulds to treat infections and of awareness that v

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Sawant, Amol M., Vishwambar D. Navale, and Koteswara Rao Vamkudoth. "Isolation and Molecular Characterization of Indigenous Penicillium chrysogenum/rubens Strain Portfolio for Penicillin V Production." Microorganisms 11, no. 5 (2023): 1132. http://dx.doi.org/10.3390/microorganisms11051132.

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Beta (β)-lactam antibiotic is an industrially important molecule produced by Penicillium chrysogenum/rubens. Penicillin is a building block for 6-aminopenicillanic acid (6-APA), an important active pharmaceutical intermediate (API) used for semi-synthetic antibiotics biosynthesis. In this investigation, we isolated and identified Penicillium chrysogenum, P. rubens, P. brocae, P. citrinum, Aspergillus fumigatus, A. sydowii, Talaromyces tratensis, Scopulariopsis brevicaulis, P. oxalicum, and P. dipodomyicola using the internal transcribed spacer (ITS) region and the β-tubulin (BenA) gene for pre

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Gil-Durán, Carlos, Diego Palma, Yudethzi Marcano, et al. "CRISPR/Cas9-Mediated Disruption of the pcz1 Gene and Its Impact on Growth, Development, and Penicillin Production in Penicillium rubens." Journal of Fungi 9, no. 10 (2023): 1010. http://dx.doi.org/10.3390/jof9101010.

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Penicillium rubens is a filamentous fungus of great biotechnological importance due to its role as an industrial producer of the antibiotic penicillin. However, despite its significance, our understanding of the regulatory mechanisms governing biological processes in this fungus is still limited. In fungi, zinc finger proteins containing a Zn(II)2Cys6 domain are particularly interesting regulators. Although the P. rubens genome harbors many genes encoding proteins with this domain, only two of them have been investigated thus far. In this study, we employed CRISPR-Cas9 technology to disrupt th

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Boruta, Tomasz, Anna Ścigaczewska, and Marcin Bizukojć. "Investigating the Stirred Tank Bioreactor Co-Cultures of the Secondary Metabolite Producers Streptomyces noursei and Penicillium rubens." Biomolecules 13, no. 12 (2023): 1748. http://dx.doi.org/10.3390/biom13121748.

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The stirred tank bioreactor co-cultures of the filamentous fungus Penicillium rubens and actinomycete Streptomyces noursei were studied with regard to secondary metabolite (SM) production, sugar consumption, and dissolved oxygen levels. In addition to the quantitative analysis of penicillin G and nystatin A1, the broad repertoire of 22 putatively identified products was semi-quantitatively evaluated with the use of UPLC-MS. Three co-cultivation variants differing with respect to the co-culture initiation method (i.e., the simultaneous inoculation of P. rubens and S. noursei and the 24 or 48 h

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Boruta, Tomasz, Anna Ścigaczewska, Agnieszka Ruda, and Marcin Bizukojć. "Effects of the Coculture Initiation Method on the Production of Secondary Metabolites in Bioreactor Cocultures of Penicillium rubens and Streptomyces rimosus." Molecules 28, no. 16 (2023): 6044. http://dx.doi.org/10.3390/molecules28166044.

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Bioreactor cocultures involving Penicillium rubens and Streptomyces rimosus were investigated with regard to secondary metabolite production, morphological development, dissolved oxygen levels, and carbon substrate utilization. The production profiles of 22 secondary metabolites were analyzed, including penicillin G and oxytetracycline. Three inoculation approaches were tested, i.e., the simultaneous inoculation of P. rubens with S. rimosus and the inoculation of S. rimosus delayed by 24 or 48 h relative to P. rubens. The delayed inoculation of S. rimosus into the P. rubens culture did not pre

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Houbraken, Jos, Jens C. Frisvad, and Robert A. Samson. "Fleming’s penicillin producing strain is not Penicillium chrysogenum but P. rubens." IMA Fungus 2, no. 1 (2011): 87–95. http://dx.doi.org/10.5598/imafungus.2011.02.01.12.

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Campos, C., T. G. Lázaro-Rodríguez, E. Hernández-Pérez, R. Rincón-Heredia, and F. J. Fernández. "Pexophagy modes during penicillin biosynthesis in Penicillium rubens P2-32-T." Archives of Microbiology 202, no. 8 (2020): 2337–41. http://dx.doi.org/10.1007/s00203-020-01939-3.

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García-Calvo, Laura, Raquel Rodríguez-Castro, Ricardo V. Ullán, et al. "Penicillium chrysogenum as a fungal factory of feruloyl esterases." Applied Microbiology and Biotechnology 107 (December 8, 2022): 691–717. https://doi.org/10.1007/s00253-022-12335-w.

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AbstractPlant biomass is a promising substrate for biorefinery, as well as a source of bioactive compounds, platform chemicals, andprecursors with multiple industrial applications. These applications depend on the hydrolysis of its recalcitrant structure.However, the effective biological degradation of plant cell walls requires several enzymatic groups acting synergistically,and novel enzymes are needed in order to achieve profitable industrial hydrolysis processes. In the present work, a feruloylesterase (FAE) activity screening of <em>Penicillium </em>spp. strains revealed a promising candid

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Hupka, Megan, Raj Kedia, Rylee Schauer, et al. "Morphology of Penicillium rubens Biofilms Formed in Space." Life 13, no. 4 (2023): 1001. http://dx.doi.org/10.3390/life13041001.

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Fungi biofilms have been found growing on spacecraft surfaces such as windows, piping, cables, etc. The contamination of these surfaces with fungi, although undesirable, is highly difficult to avoid. While several biofilm forming species, including Penicillium rubens, have been identified in spacecraft, the effect of microgravity on fungal biofilm formation is unknown. This study sent seven material surfaces (Stainless Steel 316, Aluminum Alloy, Titanium Alloy, Carbon Fiber, Quartz, Silicone, and Nanograss) inoculated with spores of P. rubens to the International Space Station and allowed biof

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Kisová, Zuzana, Andrea Šoltýsová, Mária Bučková, Gábor Beke, Andrea Puškárová, and Domenico Pangallo. "Studying the Gene Expression of Penicillium rubens Under the Effect of Eight Essential Oils." Antibiotics 9, no. 6 (2020): 343. http://dx.doi.org/10.3390/antibiotics9060343.

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Essential oils (EOs) are well-known for their beneficial properties against a broad range of microorganisms. For the better understanding of their mechanism of action in fungi, a microarray approach was used in order to evaluate the gene expression of Penicillium chrysogenum (recently renamed P. rubens) exposed to the indirect contact (vapors) of eight EOs. The selection of assayed EOs was based on their antifungal activity. The extraction of RNA and the microarray hybridization procedure were optimized for the analysis of P. rubens. Gene ontology annotation was performed to investigate the fu

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Thèses sur le sujet "Penicillium rubens"

Negre, Delphine. "Rationalisation de l’Accès aux Produits Naturels Fongiques par une Approche OSMAC in silico : Cas d’étude avec la modélisation du métabolisme de Penicillium rubens." Electronic Thesis or Diss., Nantes Université, 2024. http://www.theses.fr/2024NANU4038.

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Face à la résistance accrue aux antibiotiques menaçant la santé publique, la prospection de nouvelles molécules biologiquement actives est pressante. Les champignons filamenteux se distinguent par leur capacité à synthétiser une large gamme de produits naturels, sous l’influence de clusters de gènes biosynthétiques (BGC) qui orchestrent la production de métabolites spécialisés. Toutefois, de nombreux produits issus de ces BGCs n’ont pas encore été caractérisés et leur chimiodiversité demeure sous-explorée en raison de l’incapacité à activer l’ensemble de leur potentiel en laboratoire. L’approc

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Chapitres de livres sur le sujet "Penicillium rubens"

Larena, Inmaculada, Eduardo A. Espeso, Maria Villarino, Paloma Melgarejo, and Antonieta De Cal. "Molecular Techniques to Register and Commercialize a Penicillium rubens Strain as a Biocontrol Agent." In New and Future Developments in Microbial Biotechnology and Bioengineering. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-444-63501-3.00005-3.

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