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Articles de revues sur le sujet « Periodontal ligament »

Auteur : Grafiati

Publié le 4 juin 2021

Mis à jour le 25 juillet 2025

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1

Bahirrah, Siti, Lidya Irani Nainggolan, and Philiph Pasaribu. "Effect of Vitamin C on Tooth Movement in Terms of Periodontal Ligament Space in Guinea Pigs." Dentika Dental Journal 22, no. 2 (2019): 39–43. http://dx.doi.org/10.32734/dentika.v22i2.1677.

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Periodontal ligaments are one of the supporting tissues of teeth that undergo remodeling during the tooth movement process. Vitamin C deficiency inhibits the regeneration of collagen fibers, which are important in tissue remodeling that affects the widening of the periodontal ligament space during the process of tooth movement. The widening of periodontal ligament space can be seen by taking radiographic photos. The purpose of this study was to determine the width of the periodontal ligament space of guinea pigs by administering vitamin C, without vitamin C, and the differences between the two

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Saito, A., E. Saito, M. Kawanami, and A. Shimada. "Healing in Transplanted Teeth with Periodontal Ligament Cultured In Vitro." Cell Transplantation 12, no. 5 (2003): 519–25. http://dx.doi.org/10.3727/000000003108747082.

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Regeneration of connective tissue attachment is the ultimate goal of periodontal therapy. It has been suggested that periodontal ligament cells possess the potential to create new connective tissue attachment. However, as cells from gingiva and alveolar bone occupy the root surface during initial wound healing, population by periodontal ligament cells is limited in vivo. We have been developing a new periodontal regeneration technique using in vitro tissue culture of periodontal ligament remaining on a periodontally involved root. The purpose of this study was to examine the periodontal healin

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Sena, K., Y. Morotome, O. Baba, T. Terashima, Y. Takano, and I. Ishikawa. "Gene Expression of Growth Differentiation Factors in the Developing Periodontium of Rat Molars." Journal of Dental Research 82, no. 3 (2003): 166–71. http://dx.doi.org/10.1177/154405910308200304.

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Growth and differentiation factors (GDF) 5, 6, and 7 are known to play roles in tendon and ligament formation, and are therefore probably involved in the formation of periodontal ligament. In this study, we sought to determine temporal and spatial expression of GDF-5, -6, and -7 mRNA in developing periodontal tissue of rat molars using in situ hybridization. GDF gene expression in the periodontal ligament was first detected in cells associated with the initial process of periodontal ligament fiber bundle formation. Gene signals were also detected in cells located along the alveolar bone and ce

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Gopinathan, Gokul, Xianghong Luan, and Thomas G. H. Diekwisch. "Epigenetic Repression of RUNX2 and OSX Promoters Controls the Nonmineralized State of the Periodontal Ligament." Genes 14, no. 1 (2023): 201. http://dx.doi.org/10.3390/genes14010201.

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The nonmineralized state of the mammalian periodontal ligament is one of the hallmarks of vertebrate evolution as it provides resilient and nontraumatic tooth anchorage for effective predation. Here we sought to determine how the chromatin state of key mineralization gene promoters contributes to the nonmineralized periodontal ligament in the midst of fully mineralized alveolar bone and cementum anchor tissues. In developing mouse periodontal tissues, RUNX2 was localized to alveolar bone–lining cells, while OSX was localized throughout the periodontal ligament’s soft tissue. Matching RT-PCR am

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Brahmanta, Arya, Sutjipto Sutjipto, and Ida Bagus Narmada. "Histological changes during orthodontic tooth movement due to hyperbaric oxygen therapy." Dental Journal (Majalah Kedokteran Gigi) 49, no. 2 (2017): 63. http://dx.doi.org/10.20473/j.djmkg.v49.i2.p63-66.

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Background: Mechanical force of orthodontics causes changes in periodontal ligament vascularization and blood flow, resulting in biochemical and cellular changes as well as changes in the contour of the alveolar bone and in the thickness of the periodontal ligaments. Hyperbaric oxygen (HBO) therapy is one of many solutions stimulating the growth of new blood vessels and increasing tissue oxygenation. Thus, HBO plays a role in recovery of periodontal ligament and osteoblasts. Purpose: This study aimed to determine the effects of HBO therapy for seven days on periodontal ligament size and osteob

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Bosiakov, Sergei, and Gennadi Mikhasev. "MATHEMATICAL MODEL FOR ANALYSIS OF TRANSLATIONAL DISPLACEMENTS OF TOOTH ROOT." Mathematical Modelling and Analysis 20, no. 4 (2015): 490–501. http://dx.doi.org/10.3846/13926292.2015.1068877.

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Analytical modeling of stress-strain state of a periodontal ligament in the case of the translational displacement of a tooth root was carried out. The tooth root was assumed as a rigid body. The boundary conditions corresponding to the translational displacement of the root and fixed external surface of the periodontal ligament in the dental alveolus were considered. The system of differential equations describing the periodontal ligament’s plane-strain state induced by the translational motion of the tooth were used as the governing equations. An analytical solution was found for the governi

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Aditya, Vangara, and Kharidhi Laxman Vandana. "Management of endo-perio lesion with autologous stem cell therapy." Saudi Journal of Oral Sciences 11, no. 1 (2024): 54–59. http://dx.doi.org/10.4103/sjoralsci.sjoralsci_79_23.

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The objective of periodontal therapy is the regeneration of tooth-supporting tissues. Various treatment modalities, such as the use of bone grafting materials, guided tissue regeneration, and delivery of enamel matrix derivatives or growth factors, are applied with large variability in regenerative outcomes. However, a case report was done by utilization of autologous dental pulp stem cells and periodontal ligament stem cell niches in the treatment of bone loss associated with endodontically and periodontally involved teeth. An autologous periodontal ligament stem cells niche adherent to the r

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Pinheiro, Gabriela Veloso Vieira da Silva, Robinson Sabino-Silva, Melissa Rodrigues de Araujo, et al. "Experimental Acute Sepsis Reduced Number of Osteocalcin Immunolabeled Cells in Periodontal Ligament." Brazilian Dental Journal 31, no. 2 (2020): 143–51. http://dx.doi.org/10.1590/0103-6440202003024.

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Abstract The aim of this study was to evaluate the effect of acute sepsis in the periodontal ligament, alveolar and furcation bone in absence of periodontitis induction through histological and immunohistochemical analyses. A septic rat model was established by cecal ligation and puncture (CLP). Twelve rats were randomly divided into CLP (n=6) and Sham (n=6) groups. The animals were euthanized at 24 h and hemimandibles were submitted to histomorfometric (bone matrix, collagenous fibers, fibroblasts, osteocytes, inflammatory cells, and blood vessels) and immunohistochemical (BMP-2/4, RANKL and

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Ashrafi, Mehran, Farzan Ghalichi, Behnam Mirzakouchaki, and Iman Zoljanahi Oskui. "Numerical simulation of hydro-mechanical coupling of periodontal ligament." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 234, no. 2 (2019): 171–78. http://dx.doi.org/10.1177/0954411919887071.

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Orthodontic tooth movement in the alveolar bone is due to the mechanical response of periodontal ligament to applied forces. Definition of a proper constitutive model of the periodontal ligament to investigate its response to orthodontic loading is required. For this purpose, a three-dimensional finite element model of incisor tooth, periodontal ligament, and bone was built utilizing the hydro-mechanical coupling theory. Tooth displacement in response to orthodontic loading was then investigated, and the effect of different mechanical behaviors assigned to the solid phase of the periodontal li

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Anneroth, G., K. H. Danielsson, H. Evers, K. G. Hedström, and Å. Nordenram. "Periodontal ligament injection." International Journal of Oral Surgery 14, no. 6 (1985): 538–43. http://dx.doi.org/10.1016/s0300-9785(85)80061-2.

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Kramer, P. R., S. Nares, S. F. Kramer, D. Grogan, and M. Kaiser. "Mesenchymal Stem Cells Acquire Characteristics of Cells in the Periodontal Ligament in vitro." Journal of Dental Research 83, no. 1 (2004): 27–34. http://dx.doi.org/10.1177/154405910408300106.

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Mesenchymal stem cells differentiate into multiple types of cells derived from mesenchyme. Periodontal ligament cells are primarily derived from mesenchyme; thus, we expected mesenchymal stem cells to differentiate into periodontal ligament. Using a combination of immunohistochemistry and in situ hybridization on co-cultures of mesenchymal stem cells and periodontal ligament, we observed a significant increase in mesenchymal stem cells’ expression of osteocalcin and osteopontin and a significant decrease in expression of bone sialoprotein, characteristics of periodontal ligament in vivo. Incre

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Hafiedz, Maulana, and Nuzul. "The Role of Periodontal Ligament Remodeling on Orthodontic Tooth Movement." INTERNATIONAL JOURNAL OF MEDICAL SCIENCE AND CLINICAL RESEARCH STUDIES 03, no. 11 (2023): 2636–40. https://doi.org/10.5281/zenodo.10319906.

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The periodontal ligament is a connective tissue located between the cementum that covers the roots of the tooth and alveolar bone, which is composed of large amounts of fibers, cells, and blood vessels. Orthodontic tooth movements are obtained through periodontal ligament remodeling and alveolar bone in response to orthodontic forces. When the orthodontic force is applied to the teeth, an injury will occur in the periodontal ligament, and the pressure and tension side in the periodontal ligament is formed. Furthermore, vasoconstriction occurs in blood vessels and hypoxia in the periodontal lig

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13

Wang, Penglai, Wen Wang, Tengyu Geng, et al. "EphrinB2 regulates osteogenic differentiation of periodontal ligament stem cells and alveolar bone defect regeneration in beagles." Journal of Tissue Engineering 10 (January 2019): 204173141989436. http://dx.doi.org/10.1177/2041731419894361.

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EphrinB2, a membrane protein regulating bone homeostasis, has been demonstrated to induce osteogenic gene expression in periodontal ligament fibroblasts. The aim of this study was to explore the effects of ephrinB2 on osteogenic differentiation of periodontal ligament stem cells and on alveolar bone regeneration in vivo. We assessed the osteogenic gene expression and osteogenic differentiation potential of ephrinB2-modified human and canine periodontal ligament stem cells, in which ephrinB2 expression was upregulated via lentiviral vector transduction. EphrinB2-modified canine periodontal liga

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Lee, J.-H., B. A. Pryce, R. Schweitzer, M. I. Ryder, and S. P. Ho. "Differentiating zones at periodontal ligament-bone and periodontal ligament-cementum entheses." Journal of Periodontal Research 50, no. 6 (2015): 870–80. http://dx.doi.org/10.1111/jre.12281.

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Lauer, Günter, and Byung Ho Choi. "The ultrastructure of the periodontal ligament cells-titanium interface with vitro." Malaysian Journal of Oral and Maxillofacial Surgery 1, no. 1 (2000): 11–16. https://doi.org/10.4103/mjoms_200011_11.

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Several studies have shown that a peridontal ligament can form on titanium dental implants which were placed in contact with the periodontal ligament of the retained roots. However, the following question is still critical: how do the periodontal ligament cells adhere to the implant surface? Little is known about the ultrastructure of the periodontal ligament cells-titanium interface. The objective of this study, therefore, was to gain insight into the morphology of the interface. Human periodontal ligament cells were cultured on thin titanium substrates obtained by electron beam evaporation o

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Seo, B. M., M. Miura, W. Sonoyama, C. Coppe, R. Stanyon, and S. Shi. "Recovery of Stem Cells from Cryopreserved Periodontal Ligament." Journal of Dental Research 84, no. 10 (2005): 907–12. http://dx.doi.org/10.1177/154405910508401007.

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Human post-natal stem cells possess a great potential to be utilized in stem-cell-mediated clinical therapies and tissue engineering. It is not known whether cryopreserved human tissues contain functional post-natal stem cells. In this study, we utilized human periodontal ligament to test the hypothesis that cryopreserved human periodontal ligament contains retrievable post-natal stem cells. These cryopreserved periodontal ligament stem cells maintained normal periodontal ligament stem cell characteristics, including expression of the mesenchymal stem cell surface molecule STRO-1, single-colon

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Gomes Viana, Mariana Vitória, Júlia Santos Cerqueira, and Regina Lucia Seixas Pinto. "APLICAÇÃO DIAGNÓSTICA DE IMAGENS TRIDIMENSIONAIS (3D) NA DOENÇA PERIODONTAL DIAGNOSTIC APPLICATION OF THREE-DIMENSIONAL IMAGES (3D) IN PERIODONTAL DISEASE." Revista da Faculdade de Odontologia da Universidade Federal da Bahia 50, no. 1 (2020): 57–51. http://dx.doi.org/10.9771/revfo.v50i1.37117.

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A doença periodontal é uma doença altamente prevalente na populaçãomundial e se caracteriza pela destruição progressiva do ligamento periodontale reabsorção da crista óssea alveolar interdental e interradicular. Temcomo fatores etiológicos as bactérias do biofilme que associadas aos fatoresgenéticos e ambientais geram uma resposta inflamatória liberam enzimasproteolíticas e danificam o tecido de suporte dental. A avaliação da perdada inserção periodontal por exame clínico é limitada pelos instrumentosde sondagem e condições anatômicas, portanto, imagens radiográficas sãoinevitáveis para determ

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Saiyed Urvi Rangrej, Wajid. "Periodontal Ligament: As a Bite Force Distributor." International Journal of Science and Research (IJSR) 12, no. 6 (2023): 1229–34. http://dx.doi.org/10.21275/sr23609084303.

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Garna, Devy, Manmeet Kaur, Francis J. Hughes, and Mandeep Ghuman. "Comparison of the Expression of Periodontal Markers in Dental and Bone Marrow-derived Mesenchymal Stem Cells." Open Dentistry Journal 14, no. 1 (2020): 196–202. http://dx.doi.org/10.2174/1874210602014010196.

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Background: Periodontal ligament stem cells are a source of mesenchymal stem cells, but it is unclear whether their phenotype is distinct from mesenchymal stem cells derived from different tissues, such as those derived from bone marrow. Objective: To investigate the expression of the putative PDL markers asporin, periostin, nestin and cementum protein 1, by periodontal ligament stem cells both constitutively and during osteogenic differentiation when compared to bone marrow-derived mesenchymal stem cells, and dental pulp stem cells. Methods: The primary human periodontal ligament, bone marrow

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Song, In Seok, Yoon Sic Han, Joo-Hee Lee, Soyoun Um, Hui Young Kim, and Byoung Moo Seo. "Periodontal Ligament Stem Cells for Periodontal Regeneration." Current Oral Health Reports 2, no. 4 (2015): 236–44. http://dx.doi.org/10.1007/s40496-015-0060-0.

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Kim, Eun-Nam, Woguti Yvonne Nabende, Hyeyoon Jeong, Dongyup Hahn, and Gil-Saeng Jeong. "The Marine-Derived Natural Product Epiloliolide Isolated from Sargassum horneri Regulates NLRP3 via PKA/CREB, Promoting Proliferation and Anti-Inflammatory Effects of Human Periodontal Ligament Cells." Marine Drugs 19, no. 7 (2021): 388. http://dx.doi.org/10.3390/md19070388.

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Currently, periodontitis treatment relies on surgical operations, anti-inflammatory agents, or antibiotics. However, these treatments cause pain and side effects, resulting in a poor prognosis. Therefore, in this study, we evaluated the impact of the compound epiloliolide isolated from Sargassum horneri on the recovery of inflammatory inhibitors and loss of periodontal ligaments, which are essential treatment strategies for periodontitis. Here, human periodontal ligament cells stimulated with PG-LPS were treated with the compound epiloliolide, isolated from S. horneri. In the results of this s

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Ardan, Rachman, Ine Suhartina, Rasmi Rikmasari, Gantini Subrata, Erna Kurnikasari, and Deddy Firman. "Ligamen periodontal sebagai pendukung gaya kunyah Periodontal ligament acts to support mastication force." Journal of Dentomaxillofacial Science 10, no. 1 (2011): 60. http://dx.doi.org/10.15562/jdmfs.v10i1.254.

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Support for removable partial denture (RPD) can be obtained from bone supported mucosa and or from periodontalligament of tooth. Support can also be obtained from implant. Tooth support (periodontal ligament) is better thanmucosal support because histologically, anatomically, and also physiologically, in addition, periodontal ligamentacts to resist mastication force

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Cho, Moon-Il. "Periodontal Ligament and Cementum." Advances in Dental Research 9, no. 3_suppl (1995): 17. http://dx.doi.org/10.1177/0895937495009003s0801.

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Huang, Denghao, Jie Lei, Xingrui Li, Zhonghao Jiang, Maoxuan Luo, and Yao Xiao. "Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment." Stem Cells International 2022 (September 20, 2022): 1–24. http://dx.doi.org/10.1155/2022/9806887.

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Background. Angiogenic tissue engineering is a vital problem waiting to be settled for periodontal regeneration. Erythropoietin, a multieffect cytokine, has been reported as a protective factor for cell fate. According to our previous study, erythropoietin has a significantly angiogenic effect on periodontal ligament stem cells. To further explore its potential effects and mechanism, we studied biological behaviors of periodontal ligament stem cells under inflammatory microenvironment induced by different concentrations (0, 10, 20, 50, and 100 ng/mL) of tumor necrosis factor-α (TNF-α) and exam

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Komala, Devi, Muhammad Nurul Amin, and Yani Corvianindya Rahayu. "Uji Sitotoksisitas Hidroksiapatit Cangkang Telur Ayam Ras (Gallus gallus) terhadap Sel Fibroblas Ligamen Periodontal Manusia." STOMATOGNATIC - Jurnal Kedokteran Gigi 19, no. 1 (2022): 49. http://dx.doi.org/10.19184/stoma.v19i1.30702.

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Periodontitis is an inflammation disease of the periodontal tissues surrounding the teeth, include periodontal ligament fibroblast cell. The recently researches developed tissue engineering concept to accelerate regeneration and proliferation periodontal ligament cells. One of the major components of tissue engineering is scaffold. The hydroxyapatite is biomaterial that can be used as scaffold. The egg shell has the potential biowaste to be a source of hydroxyapatite biomaterial. Before being applied as a scaffold in the medical field, cytotoxicity testing needs to be done. This study aimed to

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Yoshizawa, Tatsuya, Fumio Takizawa, Futabako Iizawa, et al. "Homeobox Protein Msx2 Acts as a Molecular Defense Mechanism for Preventing Ossification in Ligament Fibroblasts." Molecular and Cellular Biology 24, no. 8 (2004): 3460–72. http://dx.doi.org/10.1128/mcb.24.8.3460-3472.2004.

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ABSTRACT Ligaments and tendons are comprised of tough yet flexible connective tissue. Little is known, however, about the precise characteristics of the cells in ligaments and tendons due to the absence of specific markers and cell lines. We recently reported a periodontal ligament cell line, PDL-L2, with suppressed Runx2/Osf2 transcriptional activity and an inability to form mineralized nodules. The present study demonstrates that the homeobox protein Msx2 is a key factor in suppressing those two functions. Msx2 colocalizes with Runx2/Osf2 and suppresses its activity cooperatively, acting wit

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Dr., Yadav Chakravarthy, and G. Vinay Kumar Chowdary Dr. "QUANTITATIVE AND QUALITATIVE MINERALIZATION EVALUATION OF DENTAL PULPAL AND PERIODONTAL LIGAMENT STEM CELLS USING OSTEOIMAGE ASSAY – AN IN VITRO COMPARITIVE STUDY." International Journal of Applied and Advanced Scientific Research (IJAASR) 5, no. 1 (2020): 24–31. https://doi.org/10.5281/zenodo.3884134.

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The aim of this study is to evaluate the qualitative and quantitative mineralization ability of dental pulp and periodontal ligament stem cells using osteoimage assay. Comparing the quantitative and qualitative ability of dental pulp and periodontal stem cells using osteoimage assay. Osteogenic mineralization ability of dental pulp and periodontal ligament stem cells help to regenerate the bony defects in the periapical areas of the teeth. Investigating and comparing weather dental pulp or periodontal ligament stem cells aid in the mineralization ability, the objective of this study. Osteogeni

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Asakawa, Takeyoshi, Atsushi Yamada, Masumi Kugino, et al. "Establishment of Down’s syndrome periodontal ligament cells by transfection with SV40T-Ag and hTERT." Human Cell 35, no. 1 (2021): 379–83. http://dx.doi.org/10.1007/s13577-021-00621-0.

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AbstractDown’s syndrome is one of the most common human congenital genetic diseases and affected patients have increased risk of periodontal disease. To examine involvement of the disease with periodontal disease development, we established immortalized periodontal ligament cells obtained from a Down’s syndrome patient by use of SV40T-Ag and hTERT gene transfection. Expressions of SV40T-Ag and hTERT were observed in periodontal ligament cell-derived immortalized cells established from healthy (STPDL) and Down’s syndrome patient (STPDLDS) samples. Primary cultured periodontal ligament cells obt

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Sehar, Dr Kousain. "Periodontal Ligament: Role of Fibroblast in Periodontal Healing." International Journal for Research in Applied Science and Engineering Technology 8, no. 6 (2020): 1494–503. http://dx.doi.org/10.22214/ijraset.2020.6244.

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Hatakeyama, J., D. Philp, Y. Hatakeyama, et al. "Amelogenin-mediated Regulation of Osteoclastogenesis, and Periodontal Cell Proliferation and Migration." Journal of Dental Research 85, no. 2 (2006): 144–49. http://dx.doi.org/10.1177/154405910608500206.

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We previously reported that amelogenin isoforms M180 and leucine-rich amelogenin peptide (LRAP) are expressed in the periodontal region, and that their absence is associated with increased cementum defects in amelogenin-knockout (KO) mice. The aim of the present study was to characterize the functions of these isoforms in osteoclastogenesis and in the proliferation and migration of cementoblast/periodontal ligament cells. The co-cultures of wild-type (WT) osteoclast progenitor and KO cementoblast/periodontal ligament cells displayed more tartrate-resistant acid phosphatase (TRAP)-positive cell

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Soares, Carlos José, Eliane Cristina Gava Pizi, Rodrigo Borges Fonseca, and Luis Roberto Marcondes Martins. "Influence of root embedment material and periodontal ligament simulation on fracture resistance tests." Brazilian Oral Research 19, no. 1 (2005): 11–16. http://dx.doi.org/10.1590/s1806-83242005000100003.

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The aim of this study was to evaluate the influence of the embedment material and periodontal ligament simulation on fracture resistance of bovine teeth. Eighty bovine incisor teeth were randomized into 8 groups (n = 10), embedded in acrylic or polystyrene resin using 4 types of periodontal ligament simulation: 1 - absence of the ligament; 2 - polyether impression material; 3 - polysulfide impression material; 4 - polyurethane elastomeric material. The specimens were stored at 37°C and 100% humidity for 24 hours. Specimens were submitted to tangential load on the palatal surface at 0.5 mm/minu

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Zhao, Yang, Yujia Gong, Xianbo Liu, Jia He, Bowen Zheng, and Yi Liu. "The Experimental Study of Periodontal Ligament Stem Cells Derived Exosomes with Hydrogel Accelerating Bone Regeneration on Alveolar Bone Defect." Pharmaceutics 14, no. 10 (2022): 2189. http://dx.doi.org/10.3390/pharmaceutics14102189.

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Introduction: this study was conducted to investigate the osteogenic ability of periodontal ligament stem cells (PDLSCs) derived exosomes (PDLSCs-Exos) and the effect of PDLSCs-Exos with hydrogel on alveolar bone defect repairment in the rat. Methods: the PDLSCs were obtained through primary cell culture, and PDLSCs-Exos were purified by the ultracentrifugation method. The CCK-8 kit and ALP staining were used to explore the effect of PDLSCs-Exos on promoting the proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). In vivo, the alveolar bone defect models

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Zhou, ZX, S. Zhang, and LH Ge. "Impact of Er: YAG Laser Irradiation on the Proliferation of Human Periodontal Ligament Fibroblasts." International Journal of Dentistry and Oral Science (IJDOS) 2, no. 9 (2015): 142–46. https://doi.org/10.19070/2377-8075-1500030.

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Abstract The key to success of replantation of totally avulsed teeth is periodontal ligament activity. Improving the activity of periodontal ligament cell is beneficial to the success rate of tooth replantation. Objectives: To observe the changes in proliferation of human periodontal ligament fibroblasts cultured in vitro after Er:YAG laser irradiation. Methods: Conventional immumohistochemical staining was performed on human periodontal ligament fibroblasts cultured in vitro which was obtained from teeth root surface to identify the cell source. The fifth generation of human pe

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Nascimento, Marvin do, Bruno Martins de Souza, and Aline Tany Posch. "peri-implant ligament." Brazilian Journal of Oral Sciences 22 (January 26, 2023): e231269. http://dx.doi.org/10.20396/bjos.v22i00.8671269.

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The peri-implant ligament is formed from the interface of bone tissue, through the anchoring of proteins and the surface of the dental implant. In this sense, it is relevant to understand the extent to which this ligament is structured and biomimics the periodontal ligament functions. Aim: The goal of this scoping review is to present and analyze the peri-implant ligament composition and compare the extent to which this ligament is structured and biomimics the periodontal ligament functions. Methods: This scoping review was performed according to the Joanna Briggs Institute methodology for sco

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Choriyev, Jahongir Olimjon o'g'li. "PERIODONTAL REGENERATIV TERAPIYAGA ASOSLANGAN O'SIMLIKLARDAN FOYDALANISH VA HAYVON MAHSULOTLARINING BIOMATERIALSHUNOSLIKDAGI AHAMYATI." CENTRAL ASIAN JOURNAL OF ACADEMIC RESEARCH 1, no. 1 (2023): 56–62. https://doi.org/10.5281/zenodo.8398761.

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Hozirgi kunda zamonaviy biotexnologiya,to’qima muhandisligiga  oid bilimlarning ortishi tibbiyotda muhim kasalliklarga yechim bo’lmoqda. Regenerativ periodontal terapiyaning yakuniy maqsadi "tishning periodontal kasallik yoki tish jarohati tufayli yo'qolgan qo'llab-quvvatlovchi periodontal to'qimalarni (ya'ni, yangi periodontal ligament, periodontal ligament tolalari kiritilgan yangi tsement va yangi alveolyar suyak) oldindan tiklash".C. quadrangularis poyasining ekstraktlari yallig'lanishga qarshi xususiyatlarni ko'rsatdi  va osteoblast

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Hasegawa, Tomoka, Yukina Miyamoto-Takasaki, Miki Abe, et al. "Histochemical examination on principal collagen fibers in periodontal ligaments of ascorbic acid-deficient ODS-od/od rats." Microscopy 68, no. 5 (2019): 349–58. http://dx.doi.org/10.1093/jmicro/dfz021.

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Abstract In this study, we aimed to clarify the role of ascorbic acid in collagen synthesis in periodontal ligaments using osteogenic disorder Shionogi (ODS)/ShiJcl-od/od rats lacking L-gulonolactone oxidase. These rats cannot synthesize ascorbic acid in vivo. Eight-week-old ODS/ShiJcl-od/od male rats were administered ascorbic acid solution at a concentration of 200 mg/dL (control group, n = 6) or ascorbic acid solution at concentration of 0.3 mg/dL (insufficient group, n = 12). Six rats of the insufficient group were then given with ascorbic acid solution at concentration of 200 mg/dL for ad

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Luay, Thanoon Younis, Masood Mohd, Ismail Elsayed Bahnasi Faisal, Nur Ashikin Abd Rahman Aida, and Ibrahim Abu Hassan Mohamed. "The Role of Components and Molecules of Periodontal Ligament in Orthodontic Tooth Movement." Asian Journal of Dental Sciences 2, no. 2 (2019): 1–12. https://doi.org/10.5281/zenodo.3555157.

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Orthodontic treatment requires moving and aligning the teeth into a favorable position aesthetically and functionally. To achieve that, the teeth are subjected to forces to push them to their new position. Loading of force on the crown causes tipping of tooth, subsequently the periodontal ligament is compressed adjacent to the alveolar bone on the side toward which the force is directed. On the opposite side of the root, the periodontal ligament is stretched and undergoing tension. Blood vessels are compressed and blood flow is decreased on the compression side, hence less oxygen supply is rec

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Karthikeya Patil, Mahima VG, Poornima Chandran, Bharathi Penumatsa, Nagabhushana Doggalli, and Sanjay CJ. "Age Estimation Using the Radiographic Visibility of the Periodontal Ligament in Mandibular Third Molars in Mysore Population- A Retrospective Study." Indian Journal of Forensic Medicine & Toxicology 15, no. 3 (2021): 269–75. http://dx.doi.org/10.37506/ijfmt.v15i3.15316.

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Objectives: This study was conducted to assess the reliability of age estimation using the radiographic visibility of periodontal ligament surrounding the roots of completely erupted mandibular 3rd molar.Materials and methods:Visibility ofperiodontal ligament was assessed in completely erupted mandibular third molars, in a sample of 135 panoramic radiographs, of which 55 belonging to females and 80 to males, from a Mysore population aged 18to 32 years. A classification of four stages based on the visual phenomenon of disappearance of the periodontal ligament of fully mineralized third molars w

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Mahwish Sami, Sarwat Memon, Fizza Saher, and Qudsia Hassan. "Radiographic association of chronological age based on the root pulp and periodontal ligament visibility in lower second molar teeth in a subset of the Pakistani population." Journal of the Pakistan Medical Association 74, no. 11 (2024): 1937–41. http://dx.doi.org/10.47391/jpma.10605.

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Objective: To find radiographic association of the root pulp visibility and periodontal ligament visibility stages of lower second molar teeth with chronological age. Method: The prospective, analytical, cross-sectional study was conducted after approval from the ethics review committee of Ziauddin University, Karachi, and comprised digital orthopantomograms from 2020 to 2022. The orthopantomograms related to lower second molar teeth from the left side of the mandible of individuals of either gender aged 18-40 years. The orthopantomograms were subjected to stage classification to assess the ra

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Feller, L., R. A. G. Khammissa, I. Schechter, G. Thomadakis, J. Fourie, and J. Lemmer. "Biological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic Forces." Scientific World Journal 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/876509.

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Orthodontic force-induced stresses cause dynamic alterations within the extracellular matrix and within the cytoskeleton of cells in the periodontal ligament and alveolar bone, mediating bone remodelling, ultimately enabling orthodontic tooth movement. In the periodontal ligament and alveolar bone, the mechanically induced tensile strains upregulate the expression of osteogenic genes resulting in bone formation, while mechanically induced compressive strains mediate predominantly catabolic tissue changes and bone resorption. In this review article we summarize some of the currently known biolo

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Mustafa, Manal, Ahmed Zarrough, Anne Isine Bolstad, et al. "Resolvin D1 protects periodontal ligament." American Journal of Physiology-Cell Physiology 305, no. 6 (2013): C673—C679. http://dx.doi.org/10.1152/ajpcell.00242.2012.

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Resolution agonists are endogenous mediators that drive inflammation to homeostasis. We earlier demonstrated in vivo activity of resolvins and lipoxins on regenerative periodontal wound healing. The goal of this study was to determine the impact of resolvin D1 (RvD1) on the function of human periodontal ligament (PDL) fibroblasts, which are critical for wound healing during regeneration of the soft and hard tissues around teeth. Primary cells were cultured from biopsies obtained from three individuals free of periodontal diseases. Peripheral blood mononuclear cells were isolated by density gra

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Lund, Amy E. "PERIODONTAL LIGAMENT STEM CELLS ISOLATED." Journal of the American Dental Association 135, no. 9 (2004): 1236. http://dx.doi.org/10.14219/jada.archive.2004.0393.

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Cuoghi, Osmar Aparecido, Pedro Marcelo Tondelli, Carlos Alberto Aiello, Marcos Rogério de Mendonça, and Silvano Cesar da Costa. "Importance of periodontal ligament thickness." Brazilian Oral Research 27, no. 1 (2013): 76–79. http://dx.doi.org/10.1590/s1806-83242013000100014.

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Mody, Dhawal Rajendra, Vrushali Lathiya, and Kamalkishor Mankar. "Periostin in Periodontics: A Brief Insight." International Journal of Science and Healthcare Research 6, no. 2 (2021): 147–49. http://dx.doi.org/10.52403/ijshr.20210426.

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The prime objective of the periodontal treatment is to re-establish the lost periodontal tissue by forming new attachment of periodontal ligament, cementum and the alveolar bone. Periostin is a matricellular protein with its structure closely resembling to that of Drosophila fasciclin. It is expressed in the periodontal ligament, periosteum, alveolar bone, adipose tissue as well as skeletal tissue and has a key role in role in tooth development. This protein molecule has a striking similarity to the molecule beta ig-h3 which is induced by transforming growth factor beta (TGF-beta), promotes th

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Koskinen Holm, Cecilia, Sara Rosendahl, Per-Arne Oldenborg та Pernilla Lundberg. "The expression of signal regulatory protein alpha (SIRPα) in periodontal cells and tissue". Acta Odontologica Scandinavica 83 (11 вересня 2024): 486–92. http://dx.doi.org/10.2340/aos.v83.41391.

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Signal regulatory protein alpha (SIRPα) is mainly expressed by cells of myeloid origin. This membrane glycoprotein is shown to be involved in regulation of different inflammatory conditions, such as colitis and arthritis. However, SIRPα has not been investigated in relationship to periodontitis, an inflammatory condition affecting the tooth supporting tissues. We aim to investigate if resident cells in the periodontium express SIRPα and whether a possible expression is affected by inflammatory conditions. Primary human keratinocytes, fibroblasts, periodontal ligament cells, and osteoblasts wer

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Vaquette, C., S. Saifzadeh, A. Farag, D. W. Hutmacher, and S. Ivanovski. "Periodontal Tissue Engineering with a Multiphasic Construct and Cell Sheets." Journal of Dental Research 98, no. 6 (2019): 673–81. http://dx.doi.org/10.1177/0022034519837967.

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This study reports on scaffold-based periodontal tissue engineering in a large preclinical animal model. A biphasic scaffold consisting of bone and periodontal ligament compartments manufactured by melt and solution electrospinning, respectively, was used for the delivery of in vitro matured cell sheets from 3 sources: gingival cells (GCs), bone marrow–derived mesenchymal stromal cells (Bm-MSCs), and periodontal ligament cells (PDLCs). The construct featured a 3-dimensional fibrous bone compartment with macroscopic pore size, while the periodontal compartment consisted of a flexible porous mem

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Terranova, V. P., and U. M. E. Wikesjo. "Chemotaxis of Cells Isolated from Periodontal Tissues to Different Biological Response Modifiers." Advances in Dental Research 2, no. 2 (1988): 215–22. http://dx.doi.org/10.1177/08959374880020020401.

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Directed migration of many different cell types is necessary for uneventful wound healing to occur. From clinical periodontal regeneration procedures, it is commonly believed that periodontal ligament cells will be of critical importance in obtaining a new connective tissue attachment. Here we present data which indicate that extracellular matrix components (fibronectin) and polypeptide growth factors (FGF, TGF-a, and TGF-β) modulate the ability of periodontal ligament cells to express directed migration. These data indicate a potential role for matrix components and growth factors in clinical

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Popova, Svetlana N., Malgorzata Barczyk, Carl-Fredrik Tiger та ін. "α11β1 Integrin-Dependent Regulation of Periodontal Ligament Function in the Erupting Mouse Incisor". Molecular and Cellular Biology 27, № 12 (2007): 4306–16. http://dx.doi.org/10.1128/mcb.00041-07.

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ABSTRACT The fibroblast integrin α11β1 is a key receptor for fibrillar collagens. To study the potential function of α11 in vivo, we generated a null allele of the α11 gene. Integrin α11−/− mice are viable and fertile but display dwarfism with increased mortality, most probably due to severely defective incisors. Mutant incisors are characterized by disorganized periodontal ligaments, whereas molar ligaments appear normal. The primary defect in the incisor ligament leads to halted tooth eruption. α11β1-defective embryonic fibroblasts displayed severe defects in vitro, characterized by (i) grea

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Deguchi, T., T. Yabuuchi, R. Ando, H. Ichikawa, T. Sugimoto, and T. Takano-Yamamoto. "Increase of Galanin in Trigeminal Ganglion during Tooth Movement." Journal of Dental Research 85, no. 7 (2006): 658–63. http://dx.doi.org/10.1177/154405910608500715.

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It is known that nerve fibers containing neuropeptides such as galanin increase in the periodontal ligament during experimental tooth movement. However, the origin of galanin-containing nerve fibers in the periodontal ligament remains unclear. This study was conducted to examine our hypothesis that the increased galanin nerve fibers have a sensory neuronal origin, and that the peptide is associated with pain transmission and/or periodontal ligament remodeling during experimental tooth movement. In control rats, galanin-immunoreactive trigeminal ganglion cells were very rare and were observed p

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Sandra, Ferry, Janti Sudiono, Ciptadhi Tri Oka Binartha, Angliana Chouw, and Melanie Sadono Djamil. "Growth and Osteogenic Differentiation of CD117+ Dental Pulp and Periodontal Ligament Cells." Indonesian Biomedical Journal 9, no. 2 (2017): 78. http://dx.doi.org/10.18585/inabj.v9i2.286.

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BACKGROUND: Dental pulp stem cell (DPSC) and periodontal ligament stem cell (PDLSC) have been suggested as valuable seed cells for bone engineering, suggesting that both stem cells are potential osteogenic sources. Since DPSC and PDLSC seem like to have similar potential in bone formation, we conducted a study to compare morphology, immunophenotype and cell growth of DPSC and PDLSC isolated from the same teeth.METHODS: Human dental pulps and periodontal ligaments were obtained from freshly extracted partial impacted third molar teeth. Collected samples were digested with type I collagenase. Re

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