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Articles de revues sur le sujet « Pleuripoternt »

Auteur : Grafiati

Publié le 7 juin 2025

Mis à jour le 2 août 2025

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1

M, Usha Rani, Sarojini Devi K S S, and Seetharama Raju V. "INDUCED PLEURIPOTENT STEM CELLS: A PIONEER IN THERAPY." Journal of Evolution of Medical and Dental Sciences 3, no. 71 (2014): 15165–78. http://dx.doi.org/10.14260/jemds/2014/4038.

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Linette, Gerald P., Edward A. Stadtmauer, Marcela V. Maus, et al. "Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma." Blood 122, no. 6 (2013): 863–71. http://dx.doi.org/10.1182/blood-2013-03-490565.

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Key Points Engineered T-cell receptors can have redundant recognition of alternative protein motifs, resulting in severe cardiac toxicity. The use of induced pleuripotent stem cells (iPSCs) is a promising approach to identify potential off-target effects of engineered T cells.

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Phalgunee, Priyadarshini, Das Nayak Goutami, Kumar Mallick Ranjan, Charan Prusty Gouranga, Prava Gouda Kalyani, and Mohanty Lity. "Histomorphological Spectrum of Skin Adnexal Tumours – A Hospital Based Study." International Journal of Pharmaceutical and Clinical Research 16, no. 10 (2024): 1207–12. https://doi.org/10.5281/zenodo.14176545.

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Adnexal tumours of skin originate from the pleuripotent stem cells and they can be classified into four groups based on their differentiation towards hair follicles, sebaceous glands, apocrine glands or eccrine glands. Due to their diversity in clinical presentation, it’s a diagnostic challenge for clinicians and pathologists to give an accurate final diagnosis. Histopathology is the gold standard and along with immunohistochemistry in some cases helps in reaching the conclusive diagnosis.    

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Srinivas, G., D.V. Ramanjaneyulu, E. Muralinath, et al. "An Essential Parameters of Importance of Stem Cells in Modern Medicine Include Examples of Stem Cells Therapies in Medicine, Neuro Degenerative Diseases and Pharmacological Testing." Research and Reviews in Intensive and Critical Care Nursing 3, no. 2 (2025): 1–12. https://doi.org/10.5281/zenodo.15355227.

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<em>The goal of the multidisciplinary discipline of regenerative medicine is to restore normal function by creating, replacing, or repairing damaged or lost cells, tissues, and organs, especially during illness. By altering a patient's cells, cell-based therapies—specifically, the therapeutic use of stem cells—offer a contemporary and exciting approach to regenerative medicine that may help heal a variety of illnesses.</em>

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Re, Richard N., and Julia L. Cook. "The physiological basis of intracrine stem cell regulation." American Journal of Physiology-Heart and Circulatory Physiology 295, no. 2 (2008): H447—H453. http://dx.doi.org/10.1152/ajpheart.00461.2008.

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Intracrine peptides and proteins participate in the regulation of adult and pleuripotential embryonic-like stem cells. Included among these factors are VEGF, dynorphin, the readthrough form of acetylcholinesterase, Oct3/4, Pdx-1, Pax-6, and high-mobility group protein B1, among others. In some cases, the establishment of intracrine feedback loops can be shown to be relevant to this regulation, consistent with previously proposed principles of intracrine action. Here the role of intracrines in stem cell regulation is reviewed, with particular attention to the intracrine regulation of cardiac st

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Youker, Summer R., and Elizabeth M. Billingsley. "Combined Merkel Cell Carcinoma and Atypical Fibroxanthoma." Journal of Cutaneous Medicine and Surgery 9, no. 1 (2005): 6–9. http://dx.doi.org/10.1177/120347540500900103.

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Background: Although there are reports of squamous cell carcinoma arising within and adjacent to Merkel cell carcinoma, and one report of an atypical fibroxanthoma-like tumor arising in an irradiated recurrent Merkel cell carcinoma, there have previously been no reports of an immunohistochemically verified atypical fibroxanthoma occurring in conjunction with a Merkel cell carcinoma. Objective: We report on a neoplasm with distinct features of both Merkel cell carcinoma and atypical fibroxanthoma. Methods: Histologic and immunohistochemical evaluations were performed. Results: Our results verif

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Afroze, Syeda Neelam, Surekha Ramulu, Purnima Vadla, and Sowmya Katheramalle. "Immuno histochemical analysis of nanog – A core pleuripotent protein in oral leukoplakia and oral squamous cell carcinoma." Journal of Dental Panacea 7, no. 1 (2025): 30–36. https://doi.org/10.18231/j.jdp.2025.009.

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Pavan Kumar, B., S. Ram Mohan, A. P. Mohan, K. A. Jeevan Kumar, and B. Yashwanth Yadav. "Versatility of Pleuripotent Undifferentiated Stem Cells Aspirated from Bone Marrow and its Applications in Oral and Maxillofacial Surgery." Journal of Maxillofacial and Oral Surgery 15, no. 1 (2015): 1–11. http://dx.doi.org/10.1007/s12663-015-0793-2.

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Kitiyanant, Y., J. Saikhun, N. Kitiyanant, H. Sritanaudomchai, T. Faisaikarm, and K. Pavasuthipaisit. "189ESTABLISHMENT OF BUFFALO EMBRYONIC STEM-LIKE (ES-LIKE) CELL LINES FROM DIFFERENT SOURCES OF DERIVED BLASTOCYSTS." Reproduction, Fertility and Development 16, no. 2 (2004): 216. http://dx.doi.org/10.1071/rdv16n1ab189.

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In the pleuripotent embryonic stem (ES) cells in mammalian species are derived from the inner cell mass (ICM ) of preimplantation embryos. In the current study we report the successful isolation of pleuripotent undifferentiated buffalo ES-like cells from the ICMs of in vitro fertilization (IVF), somatic cell nuclear transfer (NT)-reconstructed and parthenogenetic (PA) embryos. The ICMs were isolated from hatched blastocysts that had spread out after 3–5 days of culture on mouse embryonic fibroblast (MEF) feeder cell layer in the presence of leukemia inhibiting factor (LIF). The production of M

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M. Patel, Mandakini, Bhavna N. Gamit, Sharmistha M. Patel, Mubin I. Patel, and Shivangi S. Gandhi. "Acinic cell carcinoma, papillary-cystic variant: a rare case diagnosed in fine needle aspiration cytology." International Journal of Research in Medical Sciences 6, no. 3 (2018): 1046. http://dx.doi.org/10.18203/2320-6012.ijrms20180638.

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Acinic Cell Carcinoma is a rarest malignant epithelial neoplasm arising from pleuripotent stem cells. ACC constitute 6% of all salivary gland tumor. Most common site is parotid. It is slowly growing tumor with female preponderance most commonly occur during fifth and sixth decades of life. Diagnosis by imaging study are complex, but USG is helpful in evaluating tumor. We are presenting a 9year female, complaint of a painless, freely movable, atraumatic swelling on left cheek measuring 2x1cm2, slowly enlarging since, 8 months. FNAC was performed from the swelling and routine stain (H and E, MGG

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Rashid, Md Mamunur, Hashim Rabbi, Azharul Islam, et al. "Solid Pseudopapillary Tumor of Pancreas: A Case Report." BIRDEM Medical Journal 3, no. 1 (2013): 54–58. http://dx.doi.org/10.3329/birdem.v3i1.17129.

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Solid pseudopapillary tumor of pancreas is a rare tumor almost exclusively affecting the young female and accounts for <1% of all pancreatic tumors. Most hypothesis suggests that the tumor arises from embryonic pleuripotent stem cells. Although mostly benign in nature, the tumor may show malignant potentials and the patient may present with hepatic, omental or other meatstasis. High index of suspicion is the key for early dianosis. Good quality imaging (USG and CT scan) & FNAC are necessary for proper evaluation of the lesion. Peroperative frozen section biopsy may be necessary to ascer

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Sreelekshmi G, Navoday Raju N R, and Raole Vaidehi. "Study of Rasayana Chikitsa through Dhatu Parinaama Nyaya W.S.R. to Stem Cells." International Journal of Research in Pharmaceutical Sciences 12, no. 1 (2021): 462–65. http://dx.doi.org/10.26452/ijrps.v12i1.4091.

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Stem cells are special cells that attain an ability to become various type of cells, present in an embryo as well as in an adult. These cells are used to replace and regenerate new organs, tissues or even an entire organism due to their self-renewing, uni or pleuripotent properties. In Ayurvedic concept, the Dhatu are developing and nourishing in a sequential manner based on the Dhatu Parinama Nyaya (Law of Transportation and Transformation). Each Dhatu or bodily tissue is formed from either Ahaara Rasa or from the elements of previous Dhatu and gives rise to the formation of next Dhatu (Sooks

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Sreelekshmi G, Navoday Raju N R, and Raole Vaidehi. "Study of Rasayana Chikitsa through Dhatu Parinaama Nyaya W.S.R. to Stem Cells." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 8061–64. http://dx.doi.org/10.26452/ijrps.v11i4.4091.

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Stem cells are special cells that attain an ability to become various type of cells, present in an embryo as well as in an adult. These cells are used to replace and regenerate new organs, tissues or even an entire organism due to their self-renewing, uni or pleuripotent properties. In Ayurvedic concept, the Dhatu are developing and nourishing in a sequential manner based on the Dhatu Parinama Nyaya (Law of Transportation and Transformation). Each Dhatu or bodily tissue is formed from either Ahaara Rasa or from the elements of previous Dhatu and gives rise to the formation of next Dhatu (Sooks

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Semina, O. V., T. N. Semenets, A. M. Poverennyi, and V. M. Man'ko. "Elimination of an accessory population involved in proliferation of pleuripotent hematopoietic stem cells from bone marrow by mouse antibrain serum." Bulletin of Experimental Biology and Medicine 100, no. 5 (1985): 1584–87. http://dx.doi.org/10.1007/bf00836174.

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Tong, AW, JC Lee, JW Fay, and MJ Stone. "Elimination of clonogenic stem cells from human multiple myeloma cell lines by a plasma cell-reactive monoclonal antibody and complement." Blood 70, no. 5 (1987): 1482–89. http://dx.doi.org/10.1182/blood.v70.5.1482.1482.

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Abstract The monoclonal antibody (MoAb) MM4 reacts with human multiple myeloma (MM) cell lines and bone marrow from patients with plasma cell dyscrasias but not with normal peripheral blood or bone marrow cells. Treatment with MM4 and rabbit complement (C') was cytotoxic to the plasma cell-derived cell lines GM 1312, RPMI 8226, and ARH-77, as demonstrated by chromium release microcytotoxicity and trypan blue exclusion assays. The same treatment eliminated greater than 99% of clonogenic myeloma stem cell colony formation of these cell lines, with less than 20% inhibition of normal human bone ma

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Tong, AW, JC Lee, JW Fay, and MJ Stone. "Elimination of clonogenic stem cells from human multiple myeloma cell lines by a plasma cell-reactive monoclonal antibody and complement." Blood 70, no. 5 (1987): 1482–89. http://dx.doi.org/10.1182/blood.v70.5.1482.bloodjournal7051482.

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The monoclonal antibody (MoAb) MM4 reacts with human multiple myeloma (MM) cell lines and bone marrow from patients with plasma cell dyscrasias but not with normal peripheral blood or bone marrow cells. Treatment with MM4 and rabbit complement (C') was cytotoxic to the plasma cell-derived cell lines GM 1312, RPMI 8226, and ARH-77, as demonstrated by chromium release microcytotoxicity and trypan blue exclusion assays. The same treatment eliminated greater than 99% of clonogenic myeloma stem cell colony formation of these cell lines, with less than 20% inhibition of normal human bone marrow pleu

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Lin, Martin Hsiu-Chu, Chiu-Yen Chung, Kuo-Tai Chen, et al. "Comparison between Polybutylcyanoacrylate Nanoparticles with Either Surface-Adsorbed or Encapsulated Brain-Derived Neurotrophic Factor on the Neural Differentiation of iPSCs." International Journal of Molecular Sciences 20, no. 1 (2019): 182. http://dx.doi.org/10.3390/ijms20010182.

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The brain-derived neurotrophic factor (BDNF) is vital in the neural differentiation of neural stem/progenitor cells, and together may have therapeutic potential for neural regeneration. In this study, a multiplexed polybutylcyanoacrylate nanoparticle (PBCA NP) delivery platform was constructed, incorporating either surface-adsorbed or encapsulated BDNF for the induction of neural differentiation in induced pleuripotent stem cells (iPSCs), where tween 80 (T80) and superparamagnetic iron oxide (SPIO) were added for central nervous system (CNS) targeting and magnetic resonance (MR) image tracking

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Hacking, S. A., and A. Khademhosseini. "Applications of Microscale Technologies for Regenerative Dentistry." Journal of Dental Research 88, no. 5 (2009): 409–21. http://dx.doi.org/10.1177/0022034509334774.

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While widespread advances in tissue engineering have occurred over the past decade, many challenges remain in the context of tissue engineering and regeneration of the tooth. For example, although tooth development is the result of repeated temporal and spatial interactions between cells of ectoderm and mesoderm origin, most current tooth engineering systems cannot recreate such developmental processes. In this regard, microscale approaches that spatially pattern and support the development of different cell types in close proximity can be used to regulate the cellular microenvironment and, as

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Anubha, Bajaj*. "The Remedial Anabasis- Cancer Stem Cells." Biomedical Research and Reviews (ISSN:2631-3944) 2, no. 2 (2019): 1–3. https://doi.org/10.31021/brr.20192111.

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<strong>Premise and Principle</strong> Emergence of cancer is contemplated as a genetic phenomenon wherein genetic evolution of malignant cells modifies the progression of individual tumour. Genetic mutations are a conjectural phenomenon and unsynchronized mutational configurations can appear. Accumulations of cancer cells articulate a dynamic environment comprised of multiple, heterogeneous tumour cell territories and distinctive molecular signatures pertaining to diverse malignancies with cogent genomic mutations. Fundamental biological processes as designated with committed cancer stem cell

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Chinnikatti, Shravana kumar, Soumya shravan, H. N. Asikur Rahaman, and Shraavya Shraavya. "New Treatments for Synovial Cell Sarcoma with Genetically Modified T-Cell?" Cancer Research and Cellular Therapeutics 6, no. 3 (2022): 01–02. http://dx.doi.org/10.31579/2640-1053/113.

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Synovial cell sarcoma is rare but very aggressive tumour if not treated early, due to the painless nature of this tumour patients normally come in late and advances stage, can occur in bones, muscle cells, cartilages, ligaments and de-novo from pleuripotent stem cells from asnywhere in the body but most commonly arm, leg, or foot, and near joints such as the wrist or ankle and possibly from any joints in the body, even from soft tissues of lung and abdomen, the other name for this tumour is called malignant synovioma.The 5 year survival after the effective primary treatment is 30-75% and the s

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Jain, Amit, Lawrence H. Einhorn, and Mary J. Brames. "Metastatic malignant transformation of teratoma to primitive neuroectodermal tumor (PNET): Results with PNET-based chemotherapy." Journal of Clinical Oncology 30, no. 15_suppl (2012): 4598. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.4598.

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4598 Background: Metastatic germ cell cancers are highly chemosensitive and have 80% cure rate with cisplatin based chemotherapy. Post-chemotherapy teratoma can usually be surgically resected. However, teratoma, which is pleuripotent tissue, can undergo malignant transformation along mesodermal elements to PNET. Unlike teratoma, PNET can metastasize and render a patient unresectable and incurable. We report the results of treatment of patients with PNET with cyclophosphamide + doxorubicin + vincristine (CAV) alternating with ifosfamide + etoposide (IE). Methods: We reviewed 81 patients with hi

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Rosen, Elliot D., Zhong Liang, Hui Song, Daniella Bischoff, Malgorzata Kamocka, and Amy Zollman. "Expression of Coagulation FVIII and FIX in Human Adipose Stromal Cells (hASC) and hASC-Derived Cells - Potential Autologous Cell Therapy for Hemophilia." Blood 110, no. 11 (2007): 767. http://dx.doi.org/10.1182/blood.v110.11.767.767.

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Abstract Pleuripotent Adipose Stromal Cells (ASCs) have the capacity to differentiate into mesodermal lineage cells such as adipocytes, myocytes, osteocytes and chondrocytes. In addition, the ASCs can trans-differentiate in vitro into hepatogenic, neurogenic, endothelial and endocrine cells. Since hASCs are relatively easy to isolate in large quantity and have high proliferative potential, they provide a potential source of stem/progenitor cells for autologous cell therapy for the regeneration of injured tissue. The goal of this study is to isolate and engraft adipose stromal cells (ASCs) to g

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Seth, Rahul, Sumeet Chandra, Stevens Michelle, Locher Emily, Zamkoff Kenneth, and Gladstone E. Gladstone. "Preliminary Toxicity Profile of High-Dose Cyclophosphamide for Severe, Refractory Multiple Sclerosis. IND: 65863." Blood 104, no. 11 (2004): 5050. http://dx.doi.org/10.1182/blood.v104.11.5050.5050.

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Abstract Introduction: The use of potentially lethal doses of chemotherapy for non-malignant illnesses is often met by clinicians and patients with great apprehension. High-dose cyclophosphamide is a non-bone marrow transplant treatment option for those afflicted by severe-refractory autoimmune illnesses mediated by autoreactive lymphocytes. The goal of this therapy is to eradicate offending autoreactive B and T cells but to spare the pleuripotent blood stem cell of any ill effect and obviate the need for stem cell rescue. While cyclophosphamide dosed at 50mg/kg/day for four consecutive days i

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Hess, Jason, Gustavo Bello-Rojas, Rebecca Studinger, et al. "Bone Regrowth Using a Pleuripotent Stem Line Derived from Peripheral Adipose Tissue." Skull Base 17, S 2 (2007). http://dx.doi.org/10.1055/s-2007-981798.

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Vasanthan, Kirthanashri S. "Gelatin Methacryloyl Bioscaffolds: A Viable Option for Alveolar Bone Tissue Engineering?" Journal of Regenerative Biology and Medicine, July 20, 2022. http://dx.doi.org/10.37191/mapsci-2582-385x-4(3)-115.

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The concept of tissue engineering involves the deposition of cells on bioscaffolds in a particular location that ultimately leads to regeneration of tissues. The combinatorial effect of cells, bioscaffolds and molecular signaling factors, works conjunctly to provide exact microenvironment mimicking the native in vivo system. Alveolar bone regeneration due to its location, poses certain challenges where appropriate mechanical loading and microbial flora need addressing during construction of the scaffold [1]. Three dimensional (3D) bioprinting has unfolded vast possibilities for bone regenerati

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Meisgen, Sabrina, Malin Hedlund, Aurelie Ambrosi, et al. "Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function." Annals of the Rheumatic Diseases, April 25, 2022, annrheumdis—2021–221714. http://dx.doi.org/10.1136/annrheumdis-2021-221714.

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ObjectiveNeonatal lupus erythematosus (NLE) may develop after transplacental transfer of maternal autoantibodies with cardiac manifestations (congenital heart block, CHB) including atrioventricular block, atrial and ventricular arrhythmias, and cardiomyopathies. The association with anti-Ro/SSA antibodies is well established, but a recurrence rate of only 12%–16% despite persisting maternal autoantibodies suggests that additional factors are required for CHB development. Here, we identify fetal genetic variants conferring risk of CHB and elucidate their effects on cardiac function.MethodsA gen

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Khaleel, Khaleed J. "Nilotinib effect on hepatic and renal functions in a sample of Iraqi patients with chronic myeloid leukemia." Iraqi Journal of Cancer and Medical Genetics 10, no. 1 (2018). http://dx.doi.org/10.29409/ijcmg.v10i1.197.

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Background: Chronic myelogenous leukemia is a clonal disorder of the pleuripotent stem cells which accounts for about 15% of leukemias. Tyrosine kinase inhibitors (TKIs) are the first line therapy for CML which have substantially improved the prognosis of CML. Nilotinib is a second generation TKI which is being used widely. as a frontline drug for CML treatment and also for imatinib resistant cases. Nilotinib has been reported to induce hepatotoxicity and to affect renal function Objectives: The current study aims to evaluate the effect of nilotinib on liver and renal function in a sample of I

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Edwards, Terri G., and David C. Bloom. "Lund Human Mesencephalic (LUHMES) Neuronal Cell Line Supports Herpes Simplex Virus 1 LatencyIn Vitro." Journal of Virology 93, no. 6 (2019). http://dx.doi.org/10.1128/jvi.02210-18.

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ABSTRACTLund human mesencephalic (LUHMES) cells are human embryonic neuronal precursor cells that can be maintained as proliferating cells due to the expression of a tetracycline-regulatable (Tet-off) v-myctransgene. They can be differentiated to postmitotic neurons by the addition of tetracycline, glial cell-derived neurotrophic factor (GDNF), and dibutyryl cAMP. We demonstrate that these cells can be infected with herpes simplex virus 1 (HSV-1) at a multiplicity of infection (MOI) of 3 with the majority of cells surviving. By 6 days postinfection, there is a loss of lytic gene transcription

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