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Articles de revues sur le sujet « PSCS »

Auteur : Grafiati

Publié le 4 juin 2021

Mis à jour le 25 avril 2022

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1

Lothman, KA*, and AW Mangel. "Pulse Synchronized Contractions (PSCs)." Journal of Cardiology and Cardiovascular Medicine 4, no. 3 (2019): 199–200. http://dx.doi.org/10.29328/journal.jccm.1001067.

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Aoki, Hiroyoshi, Hirohide Ohnishi, Kouji Hama та ін. "Autocrine loop between TGF-β1 and IL-1β through Smad3- and ERK-dependent pathways in rat pancreatic stellate cells". American Journal of Physiology-Cell Physiology 290, № 4 (2006): C1100—C1108. http://dx.doi.org/10.1152/ajpcell.00465.2005.

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Pancreatic stellate cells (PSCs) are activated during pancreatitis and promote pancreatic fibrosis by producing and secreting ECMs such as collagen and fibronectin. IL-1β has been assumed to participate in pancreatic fibrosis by activating PSCs. Activated PSCs secrete various cytokines that regulate PSC function. In this study, we have examined IL-1β secretion from culture-activated PSCs as well as its regulatory mechanism. RT-PCR and ELISA have demonstrated that PSCs express IL-1β mRNA and secrete IL-1β peptide. Inhibition of TGF-β1 activity secreted from PSCs by TGF-β1-neutralizing antibody

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Masamune, Atsushi, Kazuhiro Kikuta, Takashi Watanabe, Kennichi Satoh, Morihisa Hirota, and Tooru Shimosegawa. "Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer." American Journal of Physiology-Gastrointestinal and Liver Physiology 295, no. 4 (2008): G709—G717. http://dx.doi.org/10.1152/ajpgi.90356.2008.

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Pancreatic cancer is characterized by excessive desmoplastic reaction and by a hypoxic microenvironment within the solid tumor mass. Chronic pancreatitis is also characterized by fibrosis and hypoxia. Fibroblasts in the area of fibrosis in these pathological settings are now recognized as activated pancreatic stellate cells (PSCs). Recent studies have suggested that a hypoxic environment concomitantly exists not only in pancreatic cancer cells but also in surrounding PSCs. This study aimed to clarify whether hypoxia affected the cell functions in PSCs. Human PSCs were isolated and cultured und

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Hrabák, P., M. Kalousová, T. Krechler, and T. Zima. "Pancreatic stellate cells - rising stars in pancreatic pathologies." Physiological Research, S4 (December 30, 2021): S597—S616. http://dx.doi.org/10.33549//physiolres.934783.

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Pluripotent pancreatic stellate cells (PSCs) receive growing interest in past decades. Two types of PSCs are recognized –vitamin A accumulating quiescent PSCs and activated PSCs- the main producents of extracellular matrix in pancreatic tissue. PSCs plays important role in pathogenesis of pancreatic fibrosis in pancreatic cancer and chronic pancreatitis. PSCs are intensively studied as potential therapeutical target because of their important role in developing desmoplastic stroma in pancreatic cancer. There also exists evidence that PSC are involved in other pathologies like type-2 diabetes m

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Xu, Lu, Jianjun Zhou, Jingyu Liu, et al. "Different Angiogenic Potentials of Mesenchymal Stem Cells Derived from Umbilical Artery, Umbilical Vein, and Wharton’s Jelly." Stem Cells International 2017 (2017): 1–15. http://dx.doi.org/10.1155/2017/3175748.

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Human mesenchymal stem cells derived from the umbilical cord (UC) are a favorable source for allogeneic cell therapy. Here, we successfully isolated the stem cells derived from three different compartments of the human UC, including perivascular stem cells derived from umbilical arteries (UCA-PSCs), perivascular stem cells derived from umbilical vein (UCV-PSCs), and mesenchymal stem cells derived from Wharton’s jelly (WJ-MSCs). These cells had the similar phenotype and differentiation potential toward adipocytes, osteoblasts, and neuron-like cells. However, UCA-PSCs and UCV-PSCs had more CD146

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Plé, Sophie, Viviana Job, Andréa Dessen, and Ina Attree. "Cochaperone Interactions in Export of the Type III Needle Component PscF of Pseudomonas aeruginosa." Journal of Bacteriology 192, no. 14 (2010): 3801–8. http://dx.doi.org/10.1128/jb.00117-10.

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ABSTRACT Type III secretion (T3S) systems allow the export and translocation of bacterial effectors into the host cell cytoplasm. Secretion is accomplished by an 80-nm-long needle-like structure composed, in Pseudomonas aeruginosa, of the polymerized form of a 7-kDa protein, PscF. Two proteins, PscG and PscE, stabilize PscF within the bacterial cell before its export and polymerization. In this work we screened the 1,320-Å2 interface between the two chaperones, PscE and PscG, by site-directed mutagenesis and determined hot spot regions that are important for T3S function in vivo and complex f

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Wang, Hongqiao, Yunfan Wang, Zhipeng Xuan, et al. "Progress in Perovskite Solar Cells towards Commercialization—A Review." Materials 14, no. 21 (2021): 6569. http://dx.doi.org/10.3390/ma14216569.

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In recent years, perovskite solar cells (PSCs) have experienced rapid development and have presented an excellent commercial prospect as the PSCs are made from raw materials that are readily and cheaply available depending on simple manufacturing techniques. However, the commercial production and utilization of PSCs remain immature, leading to substantial efforts needed to boost the development of scalable fabrication of PSCs, pilot scale tests, and the establishment of industrial production lines. In this way, the PSCs are expected to be successfully popularized from the laboratory to the pho

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Wang, YanZhi, and Ruixiang Hou. "Fabrication Strategy to Promote Performance of Perovskite Solar Cells." Journal of Physics: Conference Series 2109, no. 1 (2021): 012007. http://dx.doi.org/10.1088/1742-6596/2109/1/012007.

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Abstract Improvements in process of perovskites, materials of auxiliary layers and encapsulation have significantly enhanced the performance of perovskite solar cells (PSCs). However, unified fabrication of PSCs has not been completely settled till now. Whether it is harmful to the perovskite should be concerned when selecting function layer materials and encapsulation materials of PSCs. Encapsulation is the main way to enhance the stability of PSCs. Besides, to cope with the emerging environment issues, the function layer materials can be modified to adsorb lead, preventing the leakage of lea

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Tan, Heng Liang, and Andre Choo. "Opportunities for Antibody Discovery Using Human Pluripotent Stem Cells: Conservation of Oncofetal Targets." International Journal of Molecular Sciences 20, no. 22 (2019): 5752. http://dx.doi.org/10.3390/ijms20225752.

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Pluripotent stem cells (PSCs) comprise both embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). The application of pluripotent stem cells is divided into four main areas, namely: (i) regenerative therapy, (ii) the study and understanding of developmental biology, (iii) drug screening and toxicology and (iv) disease modeling. In this review, we describe a new opportunity for PSCs, the discovery of new biomarkers and generating antibodies against these biomarkers. PSCs are good sources of immunogen for raising monoclonal antibodies (mAbs) because of the conservation of oncofe

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A. El-Manstrly, Dahlia. "Cross-cultural validation of switching costs: a four-country assessment." International Marketing Review 31, no. 4 (2014): 413–37. http://dx.doi.org/10.1108/imr-08-2011-0219.

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Purpose – The purpose of this paper is to develop a cross-cultural scale of customers’ perceived switching costs (PSCs). Customers’ PSCs function as a powerful defensive marketing tool that restrains customers from switching. Design/methodology/approach – Four sets of survey data were collected in the UK, Egypt, Germany, and China. An overall response rate of 86 percent was achieved across the four countries. Cross-cultural equivalence of the PSCs scale was assessed using multi-group confirmatory factor analysis. Findings – Tests of configural, metric, and factor variance invariance confirmed

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Quinaud, Manuelle, Jacqueline Chabert, Eric Faudry, et al. "The PscE-PscF-PscG Complex Controls Type III Secretion Needle Biogenesis in Pseudomonas aeruginosa." Journal of Biological Chemistry 280, no. 43 (2005): 36293–300. http://dx.doi.org/10.1074/jbc.m508089200.

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Type III secretion (T3S) systems play key roles in pathogenicity of many Gram-negative bacteria and are employed to inject toxins directly into the cytoplasm of target cells. They are composed of over 20 different proteins that associate into a basal structure that traverses both inner and outer bacterial membranes and a hollow, needle-like structure through which toxins travel. The PscF protein is the main component of the Pseudomonas aeruginosa T3S needle. Here we demonstrate that PscF, when purified on its own, is able to form needle-like fibers of 8 nm in width and >1 μm in length. In a

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12

Hu, Ruiyuan, Yang Li, Zhongbao Que, et al. "Low Temperature VOx Hole Transport Layer for Enhancing the Performance of Carbon-Based Perovskite Solar Cells." Journal of Nanoelectronics and Optoelectronics 16, no. 2 (2021): 273–80. http://dx.doi.org/10.1166/jno.2021.2952.

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Carbon electrode based perovskite solar cells (PSCs) have attracted more attention owing to low product cost, long term stability and simple fabrication technology. Usually carbon electrode based PSCs are fabricated without hole transport layer, which results in slow development in photovoltaic performance and practical application. In this work, we synthesized p-type semiconductor VOx films via low temperature solution process. And the prepared VOx film was introduced into the carbon electrode based PSCs as hole transport layer, which is highly beneficial to further enhance the power conversi

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Aziz, Issa, Kamil Yousif, and Naseem Abdel. "Effect of Annealing Temperature on Efficiency of Perovskite Solar Cell." Journal of Applied Science and Technology Trends 1, no. 3 (2020): 112–17. http://dx.doi.org/10.38094/jastt1338.

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In this work, a simple method for producing Perovskite solar cells [PSCs] by recycling automobile batteries is used. Trying to get rid of some structures or materials which are harm to the environment (i.e. recycled car batteries) by using lead [Pb] sheets from those battery. Also, by reusing car batteries we will avoid the disposal of toxic battery elements and provide an alternative technique, readily-available Pb source for fabricating PSCs. Perovskite solar cells [PSCs] were prepared by two-step spin coating solution method grown on the FTO glass substrate. The organo-halide PSCs consists

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Fu, Xuemei, Shouhai Wu, Bo Li, Yang Xu, and Jingfeng Liu. "Functions of p53 in pluripotent stem cells." Protein & Cell 11, no. 1 (2019): 71–78. http://dx.doi.org/10.1007/s13238-019-00665-x.

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Abstract Pluripotent stem cells (PSCs) are capable of unlimited self-renewal in culture and differentiation into all functional cell types in the body, and thus hold great promise for regenerative medicine. To achieve their clinical potential, it is critical for PSCs to maintain genomic stability during the extended proliferation. The critical tumor suppressor p53 is required to maintain genomic stability of mammalian cells. In response to DNA damage or oncogenic stress, p53 plays multiple roles in maintaining genomic stability of somatic cells by inducing cell cycle arrest, apoptosis, and sen

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Zhou, Zhen, Xiaodong Sun, Rao Yan, et al. "Resveratrol inhibits high glucose-induced activation and cytokine production of isolated primary pancreatic stellate cells." Journal of Applied Virology 8, no. 3 (2019): 35–47. http://dx.doi.org/10.21092/jav.v8i3.112.

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Objective: Activation of pancreatic stellate cells (PSCs) is detrimental to pancreas function by promoting pancreatic fibrosis. Resveratrol is a natural and pharmacologically active compound. This study is to investigate the effect of resveratrol on the bilogical behavior of PSCs under high glucose condition.Methods: Isolated primary mouse PSCs were cultured in low glucose ( 5.5 mmol/L glucose, LG group ) medium, high glucose ( 25 mmol/L glucose, HG group ) medium and treated with resveratrol ( 25 μmol/L or 50 μmol/L). Cell proliferation was examined using MTT assay. The expression of α-SMA an

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16

Sparmann, Gisela, Änne Glass, Peter Brock, et al. "Inhibition of lymphocyte apoptosis by pancreatic stellate cells: impact of interleukin-15." American Journal of Physiology-Gastrointestinal and Liver Physiology 289, no. 5 (2005): G842—G851. http://dx.doi.org/10.1152/ajpgi.00483.2004.

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There is growing evidence that pancreatic stellate cells (PSCs) produce cytokines and take part in the regulation of inflammatory processes in the pancreas. IL-15 inhibits apoptosis of various cell populations. This study was performed to investigate whether PSCs produce IL-15 and thereby can affect lymphocytes. Primary PSCs were isolated from the rat pancreas using density gradient centrifugation. mRNA expression of IL-15 was demonstrated by RT-PCR, and IL-15 protein was analyzed by immunoblotting. Lymphocytes obtained from rat mesenterial lymph nodes were cocultured with in vitro activated P

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Asaumi, Hiroshi, Shiro Watanabe, Masashi Taguchi, Mitsuo Tashiro, and Makoto Otsuki. "Externally applied pressure activates pancreatic stellate cells through the generation of intracellular reactive oxygen species." American Journal of Physiology-Gastrointestinal and Liver Physiology 293, no. 5 (2007): G972—G978. http://dx.doi.org/10.1152/ajpgi.00018.2007.

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Local tissue pressure is higher in chronic pancreatitis than in the normal pancreas. We reported recently that pressure application induces synthesis of extracellular matrix (ECM) and cytokines in pancreatic stellate cells (PSCs) and that epigallocatechin gallate (EGCG), a potent antioxidant, inhibits the transformation of PSCs from quiescent to activated phenotype and ethanol-induced synthesis of ECM and cytokines in PSCs. These results suggest that oxidative stress and reactive oxygen species (ROS) are important in PSC activation. The aim of this study was to clarify the effects of ROS on ac

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Aoki, Hiroyoshi, Hirohide Ohnishi, Kouji Hama, et al. "Cyclooxygenase-2 is required for activated pancreatic stellate cells to respond to proinflammatory cytokines." American Journal of Physiology-Cell Physiology 292, no. 1 (2007): C259—C268. http://dx.doi.org/10.1152/ajpcell.00030.2006.

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Cyclooxygenase-2 (COX-2) mediates various inflammatory responses and is expressed in pancreatic tissue from patients with chronic pancreatitis. To examine the role of COX-2 in chronic pancreatitis, we investigated its participation in regulating functions of pancreatic stellate cells (PSCs), using isolated rat PSCs. COX-2 was expressed in culture-activated PSCs but not in freshly isolated quiescent PSCs. TGF-β1, IL-1β, and IL-6 enhanced COX-2 expression in activated PSCs, concomitantly increasing the expression of α-smooth muscle actin (α-SMA), a parameter of PSC activation. The COX-2 inhibito

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Bernad, Raquel, Cian J. Lynch, Rocio G. Urdinguio, Camille Stephan-Otto Attolini, Mario F. Fraga, and Manuel Serrano. "Stability of Imprinting and Differentiation Capacity in Naïve Human Cells Induced by Chemical Inhibition of CDK8 and CDK19." Cells 10, no. 4 (2021): 876. http://dx.doi.org/10.3390/cells10040876.

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Pluripotent stem cells can be stabilized in vitro at different developmental states by the use of specific chemicals and soluble factors. The naïve and primed states are the best characterized pluripotency states. Naïve pluripotent stem cells (PSCs) correspond to the early pre-implantation blastocyst and, in mice, constitute the optimal starting state for subsequent developmental applications. However, the stabilization of human naïve PSCs remains challenging because, after short-term culture, most current methods result in karyotypic abnormalities, aberrant DNA methylation patterns, loss of i

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Lee, Wonho, Jae-Han Kim, Taesu Kim, et al. "Mechanically robust and high-performance ternary solar cells combining the merits of all-polymer and fullerene blends." Journal of Materials Chemistry A 6, no. 10 (2018): 4494–503. http://dx.doi.org/10.1039/c7ta11382j.

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Zha, Min, Wei Xu, Qing Zhai, Fengfei Li, Bijun Chen, and Zilin Sun. "High Glucose Aggravates the Detrimental Effects of Pancreatic Stellate Cells on Beta-Cell Function." International Journal of Endocrinology 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/165612.

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Background and Aims. We here assess the effects of PSCs onβ-cell function and apoptosisin vivoandin vitro.Materials and Methods.PSCs were transplanted into Wistar and Goto-Kakizaki (GK) rats. Sixteen weeks after transplantation,β-cell function, apoptosis, and islet fibrosis were assessed.In vitrothe effects of PSCs conditioned medium (PSCs-CM) and/or high concentration of glucose on INS-1 cell function was assessed by measuring insulin secretion, INS-1 cell survival, apoptosis, and endoplasmic reticulum stress (ER stress) associated CHOP expression.Results. PSCs transplantation exacerbated the

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Fueglistaler, S., S. Buss, B. P. Luo, et al. "Detailed modeling of mountain wave PSCs." Atmospheric Chemistry and Physics Discussions 3, no. 1 (2003): 253–99. http://dx.doi.org/10.5194/acpd-3-253-2003.

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Abstract. Polar stratospheric clouds (PSCs) play a key role in polar ozone depletion. In the Arctic, PSCs can occur on the mesoscale due to orographically induced gravity waves. Here we present a detailed study of a mountain wave PSC event on 25–27 January 2000 over Scandinavia. The mountain wave PSCs were intensively observed by in-situ and remote-sensing techniques during the second phase of the SOLVE/THESEO-2000 Arctic campaign. We use these excellent data of PSC observations on 3 successive days to analyze the PSCs and to perform a detailed comparison with modeled clouds. We simulated the

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Fueglistaler, S., S. Buss, B. P. Luo, et al. "Detailed modeling of mountain wave PSCs." Atmospheric Chemistry and Physics 3, no. 3 (2003): 697–712. http://dx.doi.org/10.5194/acp-3-697-2003.

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Abstract. Polar stratospheric clouds (PSCs) play a key role in polar ozone depletion. In the Arctic, PSCs can occur on the mesoscale due to orographically induced gravity waves. Here we present a detailed study of a mountain wave PSC event on 25-27 January 2000 over Scandinavia. The mountain wave PSCs were intensively observed by in-situ and remote-sensing techniques during the second phase of the SOLVE/THESEO-2000 Arctic campaign. We use these excellent data of PSC observations on 3 successive days to analyze the PSCs and to perform a detailed comparison with modeled clouds. We simulated the

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Herman, M., R. Santer, L. Gonzalez, P. Lecomte, and C. Verwaerde. "Observations of PSCs in polarized light." Geophysical Research Letters 18, no. 4 (1991): 775–78. http://dx.doi.org/10.1029/91gl00770.

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Achtert, P., M. Karlsson Andersson, F. Khosrawi, and J. Gumbel. "Do tropospheric clouds influence Polar Stratospheric cloud occurrence in the Arctic?" Atmospheric Chemistry and Physics Discussions 11, no. 12 (2011): 32065–84. http://dx.doi.org/10.5194/acpd-11-32065-2011.

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Abstract. The type of Polar stratospheric clouds (PSCs) as well as their temporal and spatial extent are important for the occurrence of heterogeneous reactions in the polar stratosphere. The formation of PSCs depends strongly on temperature. However, the mechanisms of the formation of solid PSCs are still poorly understood. Recent satellite studies of Antarctic PSCs have shown that their formation can be associated with deep-tropospheric clouds which have the ability to cool the lower stratosphere radiatively and/or adiabatically. In the present study, lidar measurements aboard the Cloud-Aero

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Jakubowska, Monika A., Pawel E. Ferdek, Oleg V. Gerasimenko, Julia V. Gerasimenko, and Ole H. Petersen. "Nitric oxide signals are interlinked with calcium signals in normal pancreatic stellate cells upon oxidative stress and inflammation." Open Biology 6, no. 8 (2016): 160149. http://dx.doi.org/10.1098/rsob.160149.

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The mammalian diffuse stellate cell system comprises retinoid-storing cells capable of remarkable transformations from a quiescent to an activated myofibroblast-like phenotype. Activated pancreatic stellate cells (PSCs) attract attention owing to the pivotal role they play in development of tissue fibrosis in chronic pancreatitis and pancreatic cancer. However, little is known about the actual role of PSCs in the normal pancreas. These enigmatic cells have recently been shown to respond to physiological stimuli in a manner that is markedly different from their neighbouring pancreatic acinar ce

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Yan, Bin, Liang Cheng, Zhengdong Jiang, et al. "Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21." Oxidative Medicine and Cellular Longevity 2018 (2018): 1–15. http://dx.doi.org/10.1155/2018/1346958.

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Activation of pancreatic stellate cells (PSCs) initiates pancreatic fibrosis in chronic pancreatitis and furnishes a niche that enhances the malignancy of pancreatic cancer cells (PCCs) in pancreatic ductal adenocarcinoma (PDAC). Resveratrol (RSV), a natural polyphenol, exhibits potent antioxidant and anticancer effects. However, whether and how RSV influences the biological properties of activated PSCs and the effects of these changes on tumor remain unknown. In the present study, we found that RSV impeded hydrogen peroxide-driven reactive oxygen species- (ROS-) induced activation, invasion,

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Hamukwaya, Shindume Lomboleni, Huiying Hao, Zengying Zhao, et al. "A Review of Recent Developments in Preparation Methods for Large-Area Perovskite Solar Cells." Coatings 12, no. 2 (2022): 252. http://dx.doi.org/10.3390/coatings12020252.

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The recent rapid development in perovskite solar cells (PSCs) has led to significant research interest due to their notable photovoltaic performance, currently exceeding 25% power conversion efficiency for small-area PSCs. The materials used to fabricate PSCs dominate the current photovoltaic market, especially with the rapid increase in efficiency and performance. The present work reviews recent developments in PSCs’ preparation and fabrication methods, the associated advantages and disadvantages, and methods for improving the efficiency of large-area perovskite films for commercial applicati

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Shahiduzzaman, Md, Shoko Fukaya, Ersan Y. Muslih, et al. "Metal Oxide Compact Electron Transport Layer Modification for Efficient and Stable Perovskite Solar Cells." Materials 13, no. 9 (2020): 2207. http://dx.doi.org/10.3390/ma13092207.

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Perovskite solar cells (PSCs) have appeared as a promising design for next-generation thin-film photovoltaics because of their cost-efficient fabrication processes and excellent optoelectronic properties. However, PSCs containing a metal oxide compact layer (CL) suffer from poor long-term stability and performance. The quality of the underlying substrate strongly influences the growth of the perovskite layer. In turn, the perovskite film quality directly affects the efficiency and stability of the resultant PSCs. Thus, substrate modification with metal oxide CLs to produce highly efficient and

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Yang, Shaopeng, Tiening Wang, Xiaohui Zhao, et al. "Semitransparent Polymer Solar Cells Based on Liquid Crystal Reflectors." International Journal of Photoenergy 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/689862.

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The effects of liquid crystal (LC) reflectors on semitransparent polymer solar cells (PSCs) were investigated in this paper. By improving the cathode, we manufactured semitransparent PSCs based on the conventional PSCs. We then incorporated the LC reflector into the semitransparent PSCs, which increased the power conversion efficiency (PCE) from 2.11% to 2.71%. Subsequently adjusting the concentration and spinning speed of the active layer material changed its thickness. The maximum light absorption for the active layer was obtained using the optimum thickness, and the PCE eventually reached 3

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Wang, Haoyu, Junjie Yang, Xiaodong Liu, Shuanghong Wu, and Xiangru Wang. "Effects of Preheating Treatments on the Performance of Perovskite Solar Cells." Journal of Physics: Conference Series 2160, no. 1 (2022): 012036. http://dx.doi.org/10.1088/1742-6596/2160/1/012036.

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Abstract Perovskite solar cells (PSCs) have fascinated widespread focus for prominent perfomances recently. The processing parameters in spin-coating have great influence on the efficiency of PSCs. Herein, we have researched the influence of different preheating treatments on the perfomance of PSCs. The power conversion efficiency (PCE) has a significant enhancement to 15.89% through preheating the substrate together with precursor solution simultaneously. This work promotes the development of high performance PSCs and their industrialization.

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Xin, Chenguang, Xin Zhou, Fuhua Hou, et al. "Scalable and efficient perovskite solar cells prepared by grooved roller coating." Journal of Materials Chemistry A 7, no. 4 (2019): 1870–77. http://dx.doi.org/10.1039/c8ta10092f.

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The scalability of perovskite solar cells (PSCs) is another major challenge for PSCs besides high efficiency and stability. The grooved roller coating (GRC) method here enables the scalable and continuous production of PSCs with high utilization ratio of materials.

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Achtert, P., M. Karlsson Andersson, F. Khosrawi, and J. Gumbel. "On the linkage between tropospheric and Polar Stratospheric clouds in the Arctic as observed by space–borne lidar." Atmospheric Chemistry and Physics 12, no. 8 (2012): 3791–98. http://dx.doi.org/10.5194/acp-12-3791-2012.

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Abstract. The type of Polar stratospheric clouds (PSCs) as well as their temporal and spatial extent are important for the occurrence of heterogeneous reactions in the polar stratosphere. The formation of PSCs depends strongly on temperature. However, the mechanisms of the formation of solid PSCs are still poorly understood. Recent satellite studies of Antarctic PSCs have shown that their formation can be associated with deep-tropospheric clouds which have the ability to cool the lower stratosphere radiatively and/or adiabatically. In the present study, lidar measurements aboard the Cloud-Aero

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Yu, Xing, Xiaoping Zou, Jin Cheng, et al. "Investigation on Low-temperature Annealing Process of Solution-processed TiO2 Electron Transport Layer for Flexible Perovskite Solar Cell." Materials 13, no. 5 (2020): 1031. http://dx.doi.org/10.3390/ma13051031.

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Flexible perovskite solar cells (PSCs) have received increasing attention in wearable and portable devices over the past ten years. The low-temperature process of electron transport layer plays a key role in fabricating flexible PSCs. In this paper, we improve the performance of flexible PSCs by controlling the thermodynamic procedure in the low-temperature annealing process of solution-processed TiO2 layers and modulating the precursor concentration of (6,6)-phenyl c61 butyric acid methyl ester (PC61BM) deposited on fluorine-doped tin oxide (FTO)/TiO2 substrate. The results show that slowing

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Dohme, Lea-Cathrin, David Piggott, Susan Backhouse, and Gareth Morgan. "Psychological Skills and Characteristics Facilitative of Youth Athletes’ Development: A Systematic Review." Sport Psychologist 33, no. 4 (2019): 261–75. http://dx.doi.org/10.1123/tsp.2018-0014.

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Research has identified psychological skills and characteristics (PSCs) perceived to facilitate talented youth athletes’ development. However, no systematic categorization or synthesis of these PSCs exists to date. To provide such synthesis, this systematic review aimed to identify PSCs perceived as facilitative of talented youth athletes’ development, group and label synonymous PSCs, and categorize PSCs based on definitions established by Dohme, Backhouse, Piggott, and Morgan (2017). PRISMA systematic-review guidelines were employed and a comprehensive literature search of SPORTDiscus, PsycIN

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Caselli, Paola. "Observational Studies of Pre-Stellar Cores and Infrared Dark Clouds." Proceedings of the International Astronomical Union 7, S280 (2011): 19–32. http://dx.doi.org/10.1017/s1743921311024835.

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AbstractStars like our Sun and planets like our Earth form in dense regions within interstellar molecular clouds, called pre-stellar cores (PSCs). PSCs provide the initial conditions in the process of star and planet formation. In the past 15 years, detailed observations of (low-mass) PSCs in nearby molecular cloud complexes have allowed us to find that they are cold (T < 10K) and quiescent (molecular line widths are close to thermal), with a chemistry profoundly affected by molecular freeze-out onto dust grains. In these conditions, deuterated molecules flourish, becoming the best tools to

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Chinwokwu, Eke Chijioke. "An assessment of the relationship between private security companies and the police in crime prevention in Lagos Metropolis, Nigeria." International Journal of Police Science & Management 20, no. 1 (2018): 80–93. http://dx.doi.org/10.1177/1461355718756413.

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This study examined the relationship between private security companies (PSCs) and the police during crime prevention in Lagos Metropolis, Nigeria. The study elicited data from 1500 randomly selected respondents to a self-administered survey. Data were further collected through purposive in-depth interviews. Descriptive statistics was used for data analysis. The results showed that operational collaboration and networking between PSCs and the police during crime-prevention strategies in Lagos Metropolis were imperative for achieving a crime-free society. The study shows that PSCs and the polic

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Wang, Junqi, Xiaoping Zou, Jialin Zhu, et al. "Effect of Optimization of TiO2 Electron Transport Layer on Performance of Perovskite Solar Cells with Rough FTO Substrates." Materials 13, no. 10 (2020): 2272. http://dx.doi.org/10.3390/ma13102272.

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The film quality of the electron transport layer (ETL) plays an important role in improving the performance of perovskite solar cells (PSCs). In order to reduce the effect of rough fluorine-doped SnO2 (FTO)substrate on the film quality of the TiO2 ETL, multiple cycles of spin-coating were employed to realize optimized TiO2 film and improve the performance of PSCs with rough FTO. The results show that TiO2 ETL was optimized most effectively using two spin-coating cycles, obtaining the best performance of PSCs with rough FTO. The carbon electrode-based PSCs were then demonstrated. Our work discu

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Zhang, Yue, Haiming Zhang, Xiaohui Zhang, et al. "Major Impediment to Highly Efficient, Stable and Low-Cost Perovskite Solar Cells." Metals 8, no. 11 (2018): 964. http://dx.doi.org/10.3390/met8110964.

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Organic–inorganic hybrid perovskite solar cells (PSCs) have made immense progress in recent years, owing to outstanding optoelectronic properties of perovskite materials, such as high extinction coefficient, carrier mobility, and low exciton binding energy. Since the first appearance in 2009, the efficiency of PSCs has reached 23.3%. This has made them the most promising rival to silicon-based solar cells. However, there are still several issues to resolve to promote PSCs’ outdoor applications. In this review, three crucial aspects of PSCs, including high efficiency, environmental stability, a

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Nishimura, Ken, Aya Fukuda, and Koji Hisatake. "Mechanisms of the Metabolic Shift during Somatic Cell Reprogramming." International Journal of Molecular Sciences 20, no. 9 (2019): 2254. http://dx.doi.org/10.3390/ijms20092254.

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Pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), hold a huge promise for regenerative medicine, drug development, and disease modeling. PSCs have unique metabolic features that are akin to those of cancer cells, in which glycolysis predominates to produce energy as well as building blocks for cellular components. Recent studies indicate that the unique metabolism in PSCs is not a mere consequence of their preference for a low oxygen environment, but is an active process for maintaining self-renewal and pluripotency, possibly in pr

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Mozhejko, L. A. "Role of stellate cells in the morphogenesis of chronic pancreatitis." Proceedings of the National Academy of Sciences of Belarus, Medical series 15, no. 4 (2019): 455–64. http://dx.doi.org/10.29235/1814-6023-2018-15-4-455-464.

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This review presents an analysis of the literature on the role of pancreatic stellate cells (PSCs) in the pathogenesis of fibrosis, a predominant histological feature of chronic alcoholic pancreatitis. It is shown that ethanol and toxic products of its metabolism can affect PSCs directly and indirectly, facilitating their transformation from a quiescent to an activated state. During the pathological process, PSCs interact with parenchymal and immune cells of the pancreas through cytokines and growth factors. In activated PSCs, the proliferative and migratory activity, as well as the synthesis

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Kim, Kwon, Kim, et al. "Effect of PVP-Capped ZnO Nanoparticles with Enhanced Charge Transport on the Performance of P3HT/PCBM Polymer Solar Cells." Polymers 11, no. 11 (2019): 1818. http://dx.doi.org/10.3390/polym11111818.

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We attempted surface modification in ZnO nanoparticles (NPs) synthesized by the sol–gel process with polyvinyl pyrrolidone (PVP) applied to bulk-heterojunction polymer solar cells (PSCs) as an electron transport layer (ETL). In general, ZnO NPs have trap sites due to oxygen vacancies which capture electrons and degrade the performance of the PSCs. Devices with six different PVP:Zn ratios (0.615 g, 1.230 g, 1.846 g, 2.460 g, 3.075 g, and 3.690 g) were fabricated for surface modification, and the optimized PVP:Zn ratio (2.460 g) was found for PSCs based on P3HT/PCBM. The power conversion efficie

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Li, Chenglin. "Roll-to-Roll Compatible Methods and Outlook for Perovskite Solar Cells." E3S Web of Conferences 242 (2021): 01005. http://dx.doi.org/10.1051/e3sconf/202124201005.

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Perovskite Solar Cells (PSCs) are regarded as a highly effective low-cost solar energy collector, which is promised to sustain considerable energy supplies for modern society. Roll-to-Roll (R2R) compatible PSCs fabrication method is promised to realized industrialized PSCs production. This paper presents an overview of recent R2R compatible methods for PSC fabrication, which covers five R2R compatible strategies towards industrialized R2R production. To further tackle technical obstacles towards the PSC industrialization, improving perovskite morphology, adopting ambient production conditions

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Masamune, Atsushi, Takashi Watanabe, Kazuhiro Kikuta, Kennichi Satoh, Atsushi Kanno, and Tooru Shimosegawa. "Nuclear expression of interleukin-33 in pancreatic stellate cells." American Journal of Physiology-Gastrointestinal and Liver Physiology 299, no. 4 (2010): G821—G832. http://dx.doi.org/10.1152/ajpgi.00178.2010.

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Activated pancreatic stellate cells (PSCs) play a pivotal role in pancreatic fibrosis in chronic pancreatitis and pancreatic cancer. Recent studies have suggested a role of IL-33, a newly identified IL-1 family member, in fibrosis. We here examined the expression of IL-33 and the IL-33-mediated regulation of cell functions in PSCs. PSCs were isolated from human and rat pancreas tissues. The expression of IL-33 was examined by Western blotting, PCR, ELISA, and immunostaining. The roles of IL-33 in the regulation of PSC functions were examined by using recombinant IL-33 and small interfering RNA

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Hu, Zongshan, Yanjie Xu, Jie Li, Zezhang Zhu, Yong Qiu, and Zhen Liu. "Bioinformatics Analysis and Experimental Verification Identify Downregulation of COL27A1 in Poor Segmental Congenital Scoliosis." Computational and Mathematical Methods in Medicine 2022 (February 9, 2022): 1–11. http://dx.doi.org/10.1155/2022/2616827.

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Background. Congenital scoliosis (CS) represents the congenital defect disease, and poor segmental congenital scoliosis (PSCS) represents one of its types. Delayed intervention can result in disability and paralysis. In this study, we would identify the core biomarkers for PSCS progression through bioinformatics analysis combined with experimental verification. Methods. This work obtained the GSE11854 expression dataset associated with somite formation in the GEO database, which covers data of 13 samples. Thereafter, we utilized the edgeR of the R package to obtain DEGs in this dataset. Then,

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Samruan, Worawalan, Nathalie Beaujean, and Marielle Afanassieff. "Pluripotent Stem Cells for Transgenesis in the Rabbit: A Utopia?" Applied Sciences 10, no. 24 (2020): 8861. http://dx.doi.org/10.3390/app10248861.

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Pluripotent stem cells (PSCs) possess the following two main properties: self-renewal and pluripotency. Self-renewal is defined as the ability to proliferate in an undifferentiated state and pluripotency as the capacity to differentiate into cells of the three germ layers, i.e., ectoderm, mesoderm, and endoderm. PSCs are derived from early embryos as embryonic stem cells (ESCs) or are produced by reprogramming somatic cells into induced pluripotent stem cells (iPSCs). In mice, PSCs can be stabilized into two states of pluripotency, namely naive and primed. Naive and primed PSCs notably differ

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Ivanova, Julia S., and Olga G. Lyublinskaya. "Redox Homeostasis and Regulation in Pluripotent Stem Cells: Uniqueness or Versatility?" International Journal of Molecular Sciences 22, no. 20 (2021): 10946. http://dx.doi.org/10.3390/ijms222010946.

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Pluripotent stem cells (PSCs) hold great potential both in studies on developmental biology and clinical practice. Mitochondrial metabolism that encompasses pathways that generate ATP and produce ROS significantly differs between PSCs and somatic cells. Correspondingly, for quite a long time it was believed that the redox homeostasis in PSCs is also highly specific due to the hypoxic niche of their origin—within the pre-implantation blastocyst. However, recent research showed that redox parameters of cultivated PSCs have much in common with that of their differentiated progeny cells. Moreover,

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Uchida, Chiaki, Hiroki Mizukami, Yutaro Hara, et al. "Diabetes in Humans Activates Pancreatic Stellate Cells via RAGE in Pancreatic Ductal Adenocarcinoma." International Journal of Molecular Sciences 22, no. 21 (2021): 11716. http://dx.doi.org/10.3390/ijms222111716.

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Pancreatic stellate cells (PSCs) mainly consist of cancer-associating fibroblasts in pancreatic ductal adenocarcinoma (PDAC). The receptor for advanced glycation end products (RAGE) is implicated in the pathophysiology of diabetic complications. Here, we studied the implication of RAGE in PSC activation in PDAC. The activation of cultured mouse PSCs was evaluated by qPCR. The induction of epithelial mesenchymal transition (EMT) in PDAC cell lines was assessed under stimulation with culture supernatant from activated PSCs. A total of 155 surgically resected PDAC subjects (83 nondiabetic, 18 wit

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Lee, Brian, Breanna S. Borys, Michael S. Kallos, Carlos A. V. Rodrigues, Teresa P. Silva, and Joaquim M. S. Cabral. "Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products." Bioengineering 7, no. 2 (2020): 31. http://dx.doi.org/10.3390/bioengineering7020031.

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Allogeneic cell therapy products, such as therapeutic cells derived from pluripotent stem cells (PSCs), have amazing potential to treat a wide variety of diseases and vast numbers of patients globally. However, there are various challenges related to the manufacturing of PSCs in large enough quantities to meet commercial needs. This manuscript addresses the challenges for the process development of PSCs production in a bioreactor, and also presents a scalable bioreactor technology that can be a possible solution to remove the bottleneck for the large-scale manufacturing of high-quality therape

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Navarro, Micaela, Delia A. Soto, Carlos A. Pinzon, Jun Wu, and Pablo J. Ross. "Livestock pluripotency is finally captured in vitro." Reproduction, Fertility and Development 32, no. 2 (2020): 11. http://dx.doi.org/10.1071/rd19272.

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Pluripotent stem cells (PSCs) have demonstrated great utility in improving our understanding of mammalian development and continue to revolutionise regenerative medicine. Thanks to the improved understanding of pluripotency in mice and humans, it has recently become feasible to generate stable livestock PSCs. Although it is unlikely that livestock PSCs will be used for similar applications as their murine and human counterparts, new exciting applications that could greatly advance animal agriculture are being developed, including the use of PSCs for complex genome editing, cellular agriculture

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