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Littérature scientifique sur le sujet « Pseudotype »

Auteur : Grafiati

Publié le 14 mars 2023

Mis à jour le 26 juillet 2025

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Articles de revues sur le sujet "Pseudotype"

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Chan, Eva, Gabrielle Heilek-Snyder, Nick Cammack, Surya Sankuratri, and Changhua Ji. "Development of a Moloney Murine Leukemia Virus-Based Pseudotype Anti-HIV Assay Suitable for Accurate and Rapid Evaluation of HIV Entry Inhibitors." Journal of Biomolecular Screening 11, no. 6 (2006): 652–63. http://dx.doi.org/10.1177/1087057106288881.

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There has been increasing interest in the identification of novel HIV entry inhibitors. For the discovery of these entry inhibitors, robust surrogate anti-HIV assays are highly desired. The authors report a novel anti-HIV assay system using Moloney murine leukemia viruses (MMLVs) pseudotyped with cytoplasmic tail-truncated HIV envelope protein gp140. These pseudotyped MMLV-HIVgp140 viral particles carry luciferase transcripts; therefore, robust luciferase signal can be detected in cells infected by these pseudotypes. Polycationic agent polybrene and spinoculation markedly enhanced the infectio

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Bruett, Linda, and Janice E. Clements. "Functional Murine Leukemia Virus Vectors Pseudotyped with the Visna Virus Envelope Show Expanded Visna Virus Cell Tropism." Journal of Virology 75, no. 23 (2001): 11464–73. http://dx.doi.org/10.1128/jvi.75.23.11464-11473.2001.

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ABSTRACT Pseudotype virus vectors serve as a powerful tool for the study of virus receptor usage and entry. We describe the development of murine leukemia virus (MuLV) particles pseudotyped with the visna virus envelope glycoprotein and encoding a green fluorescent protein reporter as a tool to study the expression of the visna virus receptor. Functional MuLV/visna virus pseudotypes were obtained when the cytoplasmic tail of the visna virus envelope TM protein was truncated to 3, 7, or 11 amino acids in length. MuLV/visna virus particles were used to transduce a panel of cell types from variou

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Poluri, Ananthalakshmi, Rebecca Ainsworth, Scott C. Weaver, and Richard E. Sutton. "Functional Pseudotyping of Human Immunodeficiency Virus Type 1 Vectors by Western Equine Encephalitis Virus Envelope Glycoprotein." Journal of Virology 82, no. 24 (2008): 12580–84. http://dx.doi.org/10.1128/jvi.01503-08.

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ABSTRACT We investigated the ability of western equine encephalitis virus envelope glycoproteins (WEEV GP) to pseudotype lentiviral vectors. The titers of WEEV GP-pseudotyped human immunodeficiency virus type 1 (HIV) ranged as high as 8.0 × 104 IU/ml on permissive cells. Sera from WEEV-infected mice specifically neutralized these pseudotypes; cell transduction was also sensitive to changes in pH. The host range of the pseudotyped particles in vitro was somewhat limited, which is atypical for most alphaviruses. HIV vectors pseudotyped by WEEV GP may be a useful tool for characterizing WEEV cell

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Codran, Audrey, Cathy Royer, Daniel Jaeck, et al. "Entry of hepatitis C virus pseudotypes into primary human hepatocytes by clathrin-dependent endocytosis." Journal of General Virology 87, no. 9 (2006): 2583–93. http://dx.doi.org/10.1099/vir.0.81710-0.

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Hepatitis C virus (HCV) is a major cause of chronic hepatitis worldwide. Studies of the early steps of HCV infection have been hampered by the lack of convenient in vitro or in vivo models. Although several cell-surface molecules that mediate the binding of HCV envelope proteins to target cells have been identified, mechanisms of viral entry into human hepatocytes are still poorly understood. Vesicular stomatitis virus/HCV pseudotyped viruses expressing the HCV envelope glycoproteins on the viral envelope were generated and it was found that their entry into human hepatocytes required co-expre

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Kretschmer, Maibritt, Patrycja Kadlubowska, Daniel Hoffmann, Birco Schwalbe, Heidi Auerswald, and Michael Schreiber. "Zikavirus prME Envelope Pseudotyped Human Immunodeficiency Virus Type-1 as a Novel Tool for Glioblastoma-Directed Virotherapy." Cancers 12, no. 4 (2020): 1000. http://dx.doi.org/10.3390/cancers12041000.

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Glioblastoma multiforme is the most lethal type of brain tumor that is not yet curable owing to its frequent resurgence after surgery. Resistance is mainly caused by the presence of a subpopulation of tumor cells, the glioma stem cells (GSCs), which are highly resistant to radiation and chemotherapy. In 2015, Zikavirus (ZIKV)-induced microcephaly emerged in newborns, indicating that ZIKV has a specific neurotropism. Accordingly, an oncolytic tropism for infecting GSCs was demonstrated in a murine tumor model. Like other flaviviruses, ZIKV is enveloped by two proteins, prM and E. The pME expres

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Spiegel, Martin, Michael Bitzer, Andrea Schenk, et al. "Pseudotype Formation of Moloney Murine Leukemia Virus with Sendai Virus Glycoprotein F." Journal of Virology 72, no. 6 (1998): 5296–302. http://dx.doi.org/10.1128/jvi.72.6.5296-5302.1998.

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ABSTRACT Mixed infection of cells with both Moloney murine leukemia virus (MoMLV) and related or heterologous viruses produces progeny pseudotype virions bearing the MoMLV genome encapsulated by the envelope of the other virus. In this study, pseudotype formation between MoMLV and the prototype parainfluenza virus Sendai virus (SV) was investigated. We report for the first time that SV infection of MoMLV producer cells results in the formation of MoMLV(SV) pseudotypes, which display a largely extended host range compared to that of MoMLV particles. This could be associated with SV hemagglutini

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Meyer, Keith, Aster Beyene, Terry L. Bowlin, Arnab Basu, and Ranjit Ray. "Coexpression of Hepatitis C Virus E1 and E2 Chimeric Envelope Glycoproteins Displays Separable Ligand Sensitivity and Increases Pseudotype Infectious Titer." Journal of Virology 78, no. 23 (2004): 12838–47. http://dx.doi.org/10.1128/jvi.78.23.12838-12847.2004.

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ABSTRACT We have previously reported that a pseudotype virus generated by reconstitution of hepatitis C virus (HCV) chimeric envelope glycoprotein E1-G or E2-G on the surface of a temperature-sensitive mutant of vesicular stomatitis virus (VSVts045) interacts independently with mammalian cells to initiate infection. Here, we examined whether coexpression of both of the envelope glycoproteins on pseudotype particles would augment virus infectivity and/or alter the functional properties of the individual subunits. Stable transfectants of baby hamster kidney (BHK) epithelial cells expressing eith

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Pöhlking, Celine, Sebastian Beier, Jan Patrick Formanski, Michael Friese, Michael Schreiber, and Birco Schwalbe. "Isolation of Cells from Glioblastoma Multiforme Grade 4 Tumors for Infection with Zika Virus prME and ME Pseudotyped HIV-1." International Journal of Molecular Sciences 24, no. 5 (2023): 4467. http://dx.doi.org/10.3390/ijms24054467.

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This study aimed to isolate cells from grade 4 glioblastoma multiforme tumors for infection experiments with Zika virus (ZIKV) prME or ME enveloped HIV-1 pseudotypes. The cells obtained from tumor tissue were successfully cultured in human cerebrospinal fluid (hCSF) or a mixture of hCSF/DMEM in cell culture flasks with polar and hydrophilic surfaces. The isolated tumor cells as well as the U87, U138, and U343 cells tested positive for ZIKV receptors Axl and Integrin αvβ5. Pseudotype entry was detected by the expression of firefly luciferase or green fluorescent protein (gfp). In prME and ME ps

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Sandrin, Virginie, Delphine Muriaux, Jean-Luc Darlix, and François-Loïc Cosset. "Intracellular Trafficking of Gag and Env Proteins and Their Interactions Modulate Pseudotyping of Retroviruses." Journal of Virology 78, no. 13 (2004): 7153–64. http://dx.doi.org/10.1128/jvi.78.13.7153-7164.2004.

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ABSTRACT Glycoproteins derived from most retroviruses and from several families of enveloped viruses can form infectious pseudotypes with murine leukemia virus (MLV) and lentiviral core particles, like the MLV envelope glycoproteins (Env) that are incorporated on either virus type. However, coexpression of a given glycoprotein with heterologous core proteins does not always give rise to highly infectious viral particles, and restrictions on pseudotype formation have been reported. To understand the mechanisms that control the recruitment of viral surface glycoproteins on lentiviral and retrovi

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Balliet, John W., and Paul Bates. "Efficient Infection Mediated by Viral Receptors Incorporated into Retroviral Particles." Journal of Virology 72, no. 1 (1998): 671–76. http://dx.doi.org/10.1128/jvi.72.1.671-676.1998.

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ABSTRACT Many host cell surface proteins, including viral receptors, are incorporated into enveloped viruses. To address the functional significance of these host proteins, murine leukemia viruses containing the cellular receptors for Rous sarcoma virus (Tva) or ecotropic murine leukemia virus (MCAT-1) were produced. These receptor-pseudotyped viruses efficiently infect cells expressing the cognate viral envelope glycoproteins, with titers of up to 105 infectious units per milliliter for the Tva pseudotypes. Receptor and viral glycoprotein specificity and functional requirements are maintained

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Thèses sur le sujet "Pseudotype"

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Strang, Blair Lewis. "Development and characterisation of pseudotype HIV vectors." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406402.

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Piccini, Giulia. "Evaluation of Influenza Lentiviral Pseudotypes as an alternative source of antigen in the Neuraminidase Inhibition Enzyme-Linked Lectin Assay." Doctoral thesis, Università di Siena, 2020. http://hdl.handle.net/11365/1096232.

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The continuously changing epidemiology of influenza viruses needs to be yearly addressed with a fast and massive production of vaccines that prevent epidemic outbreaks and occasional pandemics worldwide. Currently licensed flu vaccines are designed to elicit antibodies against the viral hemagglutinin (HA). Formulations containing standardized amounts of neuraminidase (NA) are however gaining growing interest in the influenza vaccine field, as NA‐inhibiting (NI) antibodies have been associated with resistance to disease as well as reduced severity and duration of illness. The Neuraminidase In

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Mahoney, Catherine H. "Studies using pseudotyped retroviral vectors." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312721.

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Grzybowski, Brad. "A pseudotyped viral vector : hPIV3-HIV-1." Thesis, Georgia Institute of Technology, 2003. http://hdl.handle.net/1853/20932.

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Thomas, Joan Helen. "Studies in gene transfer using pseudotyped lentiviral vector systems." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.621818.

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Gaiano, Nicholas R. (Nicholas Roger). "Insertional mutagenesis in zebrafish using a pseudotyped retroviral vector." Thesis, Massachusetts Institute of Technology, 1997. http://hdl.handle.net/1721.1/43311.

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Peng, Yue. "A novel vaccine strategy : replication-defective pseudotyped SIVs expressing IFN-[gamma] /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2005. http://uclibs.org/PID/11984.

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Thesis (Ph. D.)--University of California, Davis, 2005.<br>Degree granted in Comparative Pathology. On title page "[gamma]" appears as lower-case Greek letter. Also available via the World Wide Web. (Restricted to UC campuses)

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Kinsley, Rebecca. "Development of lentiviral pseudotypes for surveillance studies on animal influenza viruses." Thesis, University of Kent, 2017. https://kar.kent.ac.uk/66297/.

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Pseudotyped viruses (PVs) provide a safe, flexible platform for fundamental virological studies and antibody screening assays. Generation of influenza PVs involves co-transfection of producer cells with plasmids encoding the necessary viral components. The pseudotype virus neutralisation assay (PVNA) is a sensitive technique to measure protective antibody responses which cause neutralisation of virus particles. Many traditional methodologies, e.g. Haemagglutination Inhibition (HI) and Single Radial Haemolysis (SRH), detect only surface glycoprotein binding antibodies whereas the PVNA quantifie

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Carnell, George William. "Development of hybrid haemagglutinin pseudotyped lentiviruses to assess heterosubtypic immunity to influenza." Thesis, University of Kent, 2017. https://kar.kent.ac.uk/66363/.

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The influenza virus still causes hundreds of thousands of deaths globally, on top of morbidity and associated economic burden. We are currently at the height of efforts surrounding the development and employment of 'universal' vaccines against this virus, with clinical trials commencing on the most promising candidates. Despite this, the influenza virus poses more of a threat to human life than it ever has previously, with multiple subtypes of pandemic potential circulating around the globe. The key to current efforts lies in the priming of the immune system towards generating long lasting def

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Amsterdam, Adam (Adam Henry) 1967. "Use of a pseudotyped retoviral vector to accomplish insertional mutagenesis in zebrafish." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/50024.

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Livres sur le sujet "Pseudotype"

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Wang, Youchun, ed. Pseudotyped Viruses. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0113-5.

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Pseudotyped Viruses. Springer, 2023.

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Chapitres de livres sur le sujet "Pseudotype"

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Mi, Dan, Jiaxin Hu, and Zhaohui Qian. "A Lentiviral Pseudotype System to Characterize SARS-CoV-2 Glycoprotein." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2895-9_16.

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Nehring, Dirk, Ralf Pörtner, and Peter Czermak. "Production of Retroviral Pseudotype Vectors in Fixed Bed Reactors for Use in Gene Therapy." In Cells and Culture. Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-3419-9_107.

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Wang, Youchun, Zehua Zhou, Xi Wu, et al. "Pseudotyped Viruses." In Advances in Experimental Medicine and Biology. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0113-5_1.

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Zavada, J. "VSV(BLV) Pseudotypes." In Enzootic Bovine Leukosis and Bovine Leukemia Virus. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-2341-9_17.

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Ning, Tingting, Weijin Huang, Li Min, et al. "Pseudotyped Viruses for Orthohantavirus." In Advances in Experimental Medicine and Biology. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0113-5_12.

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Cui, Qianqian, and Weijin Huang. "Application of Pseudotyped Viruses." In Advances in Experimental Medicine and Biology. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0113-5_3.

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Wang, Meiyu, Jianhui Nie, and Youchun Wang. "Pseudotyped Viruses for Coronaviruses." In Advances in Experimental Medicine and Biology. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0113-5_7.

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Zhang, Leiliang, Xiao Wang, Annan Ming, and Wenjie Tan. "Pseudotyped Virus for Flaviviridae." In Advances in Experimental Medicine and Biology. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0113-5_17.

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Chen, Ruifeng, Weijing Huang, and Youchun Wang. "Pseudotyped Virus for Bandavirus." In Advances in Experimental Medicine and Biology. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0113-5_14.

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Li, Tao, Ziteng Liang, Weijin Huang, and Youchun Wang. "Pseudotyped Virus for Henipavirus." In Advances in Experimental Medicine and Biology. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0113-5_9.

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Actes de conférences sur le sujet "Pseudotype"

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Taveira, Elisa Borges, Marco Fidel Guevara-Vega, Igor Andrade Santos, et al. "SARS-CoV-2 structures detection in artificial saliva using ATR-FTIR associated with Linear Discriminant Analysis." In Latin America Optics and Photonics Conference. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/laop.2022.tu1c.8.

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Here, we used ATR-FTIR platform supported by artificial intelligence algorithms to identify unique infrared vibrational modes of a pseudotyped human immunodeficiency virus type-1 (HIV-1) coupled to Spike (S) protein of SARS-CoV-2 (HIV/NanoLuc-SARS-CoV-2 pseudotype virus).

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Aqila, Tasmia, and Ananda Mohan Mondal. "Pseudotime Based Analysis of Cancer Dynamics." In BCB '19: 10th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics. ACM, 2019. http://dx.doi.org/10.1145/3307339.3343253.

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Aminian, K., S. Ameri, W. E. Abbitt, and L. E. Cunningham. "Polynomial Approximations for Gas Pseudopressure and Pseudotime." In SPE Eastern Regional Meeting. Society of Petroleum Engineers, 1991. http://dx.doi.org/10.2118/23439-ms.

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Aqila, Tasmia, Abdullah Al Mamun, and Ananda Mohan Mondal. "Pseudotime Based Discovery of Breast Cancer Heterogeneity." In 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2019. http://dx.doi.org/10.1109/bibm47256.2019.8983300.

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Tabatabaie, S. Hamed, Louis Mattar, and Mehran Pooladi-Darvish. "Pseudotime Calculation in Low Permeability Gas Reservoirs." In SPE Unconventional Resources Conference Canada. Society of Petroleum Engineers, 2013. http://dx.doi.org/10.2118/167185-ms.

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E. Plessix, R., P. Milcik, C. Corcoran, H. Kuehl, and K. Matson. "Full Waveform Inversion with a Pseudotime Approach." In 74th EAGE Conference and Exhibition incorporating EUROPEC 2012. EAGE Publications BV, 2012. http://dx.doi.org/10.3997/2214-4609.20148713.

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Tishin, A. E., O. I. Yarovaya, S. S. Efstifeeva, A. R. Imatdinov, and I. R. Imatdinov. "MINIGENOMIC AND PSEUDOTYPED SYSTEMS FOR SCREENING COMPOUNDS WITH ANTIVIRAL ACTIVITY." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-262.

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This research describes approaches and genetic constructs used for high-performance screening studies of organic compounds exhibiting inhibitory activity against the replication-transcription machinery of the Puumala virus.

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Frey, Christian, Jan Backhaus, Graham Ashcroft, Georg Geiser, Benjamin Winhart, and Heinrich Stüer. "Using Pseudotime Marching for the Solution of Harmonic Balance Problems." In ASME Turbo Expo 2024: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2024. http://dx.doi.org/10.1115/gt2024-127820.

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Abstract The aim of this paper is to study approaches to implement implicit pseudotime marching for the harmonic balance system in the frequency domain. We first give a motivation for using pseudotime marching as a solution technique. It turns out that, when the discretization errors of the pseudospectral time derivative and the pseudotime derivative are neglected, the harmonic balance solution converges to a stable periodic flow, provided that the initial solution is sufficiently close to a stable periodic solution. This motivates the choice of a robust pseudotime marching approach, e.g., an

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Alton, EWFW, AC Boyd, JC Davies, et al. "S68 Towards a first-in-human trial with a pseudotyped lentivirus." In British Thoracic Society Winter Meeting, Wednesday 17 to Friday 19 February 2021, Programme and Abstracts. BMJ Publishing Group Ltd and British Thoracic Society, 2021. http://dx.doi.org/10.1136/thorax-2020-btsabstracts.73.

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Aanonsen, S. "Application of Pseudotime To Estimate Average Reservoir Pressure." In SPE Annual Technical Conference and Exhibition. Society of Petroleum Engineers, 1985. http://dx.doi.org/10.2118/14256-ms.

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