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Articles de revues sur le sujet « RBDIs »

Auteur : Grafiati

Publié le 2 juin 2025

Mis à jour le 31 juillet 2025

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1

Brindha, Subbaian, Takahiro Yoshizue, Rawiwan Wongnak, et al. "An Escherichia coli Expressed Multi-Disulfide Bonded SARS-CoV-2 RBD Shows Native-like Biophysical Properties and Elicits Neutralizing Antisera in a Mouse Model." International Journal of Molecular Sciences 23, no. 24 (2022): 15744. http://dx.doi.org/10.3390/ijms232415744.

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A large-scale Escherichia coli (E. coli) production of the receptor-binding domain (RBD) of the SARS-CoV-2 could yield a versatile and low-cost antigen for a subunit vaccine. Appropriately folded antigens can potentially elicit the production of neutralizing antisera providing immune protection against the virus. However, E. coli expression using a standard protocol produces RBDs with aberrant disulfide bonds among the RBD’s eight cysteines resulting in the expression of insoluble and non-native RBDs. Here, we evaluate whether E. coli expressing RBD can be used as an antigen candidate for a su

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Howarth, Peter H. "Mediators of nasal blockage in allergic rbtis." Allergy 52 (December 1997): 12–18. http://dx.doi.org/10.1111/j.1398-9995.1997.tb04878.x.

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Graf, Peter. "Rbtis medicamentosa: aspects of pathophysiology and treatment." Allergy 52 (December 1997): 28–34. http://dx.doi.org/10.1111/j.1398-9995.1997.tb04881.x.

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Allely, Clare. "Exploring the female autism phenotype of repetitive behaviours and restricted interests (RBRIs): a systematic PRISMA review." Advances in Autism 5, no. 3 (2019): 171–86. http://dx.doi.org/10.1108/aia-09-2018-0030.

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Purpose The purpose of this paper is to address the need for increased understanding, awareness and recognition of the autism female phenotype in terms of repetitive behaviours and restricted interests (RBRIs). Design/methodology/approach A systematic PRISMA review was conducted. The main aim of the present systematic review is to identify studies which have investigated RBRIs in females with autism spectrum disorder (ASD) or the differences in RBRIs between males and females with ASD. Findings In sum, 19 relevant articles were identified: 5 studies found no significant evidence to support the

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Gana, Bukar Abba, Isah Funtua Abdulkadir, Hassan Musa, and Tijjani Garba. "A Conceptual Framework for Organisation of River Basin Developmentand Management in Nigeria." European Journal of Engineering Research and Science 4, no. 6 (2019): 34–40. http://dx.doi.org/10.24018/ejers.2019.4.6.1308.

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River Basin Development Authorities (RBDAs) in Nigeria were established since 1976 and they operate mechanized and capital intensive programmes. All the 12 RBDAs operate as separate Authorities, each with separate administrative and operational autonomy, but sharing the Basin Resources of the 8 Hydrological Areas. However, their performance was generally described as disappointing. This study first reviewed the existing organization of the 12 RBDAs in Nigeria. Thereafter, one of the 8 Hydrological Areas – the Komadugu-Yobe Basin (KYB) – which is the major inland drainage system in Nigeria was

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Gana, Bukar Abba, Isah Funtua Abdulkadir, Hassan Musa, and Tijjani Garba. "Conceptual Framework for Organisation of River Basin Developmentand Management in Nigeria." European Journal of Engineering and Technology Research 4, no. 6 (2019): 34–40. http://dx.doi.org/10.24018/ejeng.2019.4.6.1308.

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River Basin Development Authorities (RBDAs) in Nigeria were established since 1976 and they operate mechanized and capital intensive programmes. All the 12 RBDAs operate as separate Authorities, each with separate administrative and operational autonomy, but sharing the Basin Resources of the 8 Hydrological Areas. However, their performance was generally described as disappointing. This study first reviewed the existing organization of the 12 RBDAs in Nigeria. Thereafter, one of the 8 Hydrological Areas – the Komadugu-Yobe Basin (KYB) – which is the major inland drainage system in Nigeria was

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Sabrowsky, Horst, Karin Hippler, Rolf-Dieter Hitzbleck, et al. "Zur Komplexchemie der Alkalimetalle: Kristallstruktur von RbLiS / On the Complex Chemistry of the Alkali Metals: The Crystal Structure of RbLiS." Zeitschrift für Naturforschung B 44, no. 8 (1989): 893–95. http://dx.doi.org/10.1515/znb-1989-0806.

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The colourless compound RbLiS has been prepared as described earlier (H. Sabrowsky, A. Thimm, and P. Vogt-Mertens, Z. Naturforsch. 40b, 1759 (1985)) and its crystal structure determined by X-ray diffraction. Very hygroscopic RbLiS crystallizes in the tetragonal space group P4/nmm (Z = 2) with the cell parameters a = 4.424(3) Å, c = 7.255(2) Å. The structure was solved from 1635 counter reflections (155 symmetry independent reflections) by Patterson and Fourier methods (R = 0.031; wR = 0.031).The structure is characterized by layers of ∞2[LiS4/4]-tetrahedrons separated by double-layers of Rb+ t

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Archie, Tim, Charles N. Hayward, Stan Yoshinobu, and Sandra L. Laursen. "Investigating the linkage between professional development and mathematics instructors’ use of teaching practices using the theory of planned behavior." PLOS ONE 17, no. 4 (2022): e0267097. http://dx.doi.org/10.1371/journal.pone.0267097.

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Professional development has been identified as an effective way to increase college STEM instructors’ use of research-based instructional strategies (RBIS) known to benefit student learning and persistence in STEM. Yet only a few studies relate professional development experiences to later teaching behaviors of higher education instructors. This study of 361 undergraduate mathematics instructors, all of whom participated in multi-day, discipline-based workshops on teaching held in 2010–2019, examined the relationship between such participation and later use of RBIS. We found that instructors’

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Khan, Sara, Faiza Amin, Rafat Amin, and Naresh Kumar. "Exploring the Effect of Cetylpyridinium Chloride Addition on the Antibacterial Activity and Surface Hardness of Resin-Based Dental Composites." Polymers 16, no. 5 (2024): 588. http://dx.doi.org/10.3390/polym16050588.

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The aim of this study was to evaluate the effect of cetylpyridinium chloride (CPC) addition on the antibacterial and surface hardness characteristics of two commercial resin-based dental composites (RBDCs). A total of two hundred and seventy (n = 270) specimens from Filtek Z250 Universal and Filtek Z350 XT flowable RBDCs were fabricated with the addition of CPC at 2 %wt and 4 %wt concentrations to assess their antibacterial activity using the agar diffusion test and direct contact inhibition test, and their surface hardness using the Vickers microhardness test after 1 day, 30 days, and 90 days

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Khasanova, Diana M., Zuleykha A. Zalyalova, Guzal R. Ilina, and Nailya I. Bagdanova. "Rapid eye movement sleep behavior disorder: modern concept and Parkinson’s disease correlation." Annals of Clinical and Experimental Neurology 18, no. 2 (2024): 62–69. http://dx.doi.org/10.17816/acen.980.

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This review describes the association between rapid eye movement (REM) sleep behavior disorder (RBD) and synucleinopathies, primarily Parkinson's disease. This article reviews the diagnostic criteria, the epidemiology of RBDs, their pathogenesis, and their association with early non-motor symptoms. The data are presented to assess the risk of phenoconversion of RBDs to Parkinson's disease or other synucleinopathies such as Lewy body dementia and multiple system atrophy. A prodromal period of RBDs may precede synucleinopathies years or decades before potential manifestation of motor, cognitive,

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Cosgrove, Sarah B., and Neal H. Olitsky. "From “Traditional” to Research-Based Instructional Strategies: An Assessment of Learning Gains." AEA Papers and Proceedings 108 (May 1, 2018): 302–6. http://dx.doi.org/10.1257/pandp.20181053.

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The cognitive science literature provides several research based instructional strategies (RBIS) proven to be effective in student learning. Given the prevalence of lecture-based classes and instructor-led discussions, understanding the effects of switching from the “traditional” method to employing RBIS would provide a better understanding of the value of these strategies. In this paper, we conduct a controlled experiment comparing a “traditional,” lecture-based class to a class in which these RBIS are carefully employed. Students exposed to the refined RBIS approach show significantly higher

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Zhu, Renwei, Sha Tan, Yayi Wang, Linwei Zhang, and Liang Huang. "Physicochemical Properties and Hypolipidemic Activity of Dietary Fiber from Rice Bran Meal Obtained by Three Oil-Production Methods." Foods 12, no. 19 (2023): 3695. http://dx.doi.org/10.3390/foods12193695.

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This study investigated the effects of three oil production methods on the physicochemical properties of dietary fiber from rice bran flour, and the hypolipidemic effects of the dietary fibers were investigated in vitro and in vivo. The particle size results showed that the organic-solvent-impregnated rice bran meal dietary fiber (N-RBDF) had the smallest average particle size and the aqueous enzymatic rice bran meal dietary fiber (E-RBDF) had the narrowest particle size distribution. Scanning electron microscopy (SEM) results demonstrated that all three kinds of rice bran meal dietary fibers

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Tan, Enqing, Erica Frew, Jeff Cooper, et al. "Use of Lateral Flow Immunoassay to Characterize SARS-CoV-2 RBD-Specific Antibodies and Their Ability to React with the UK, SA and BR P.1 Variant RBDs." Diagnostics 11, no. 7 (2021): 1190. http://dx.doi.org/10.3390/diagnostics11071190.

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Identifying anti-spike antibodies that exhibit strong neutralizing activity against current dominant circulating variants, and antibodies that are escaped by these variants, has important implications in the development of therapeutic and diagnostic solutions and in improving understanding of the humoral response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We characterized seven anti-SARS-CoV-2 receptor binding domain (RBD) antibodies for binding activity, pairing capability, and neutralization activity to SARS-CoV-2 and three variant RBDs via lateral flow immuno

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Ginting, Mimpin, Jamaran Kaban, Herlince Sihotang, and Hendri Tobing. "Pengaruh Suhu Interesterifikasi RBDPO/RBDPS Terhadap Komposisi Trigliserida dan Nilai Kandungan Lemak Padat dalam Pembuatan Lemak Margarin." Talenta Conference Series: Science and Technology (ST) 2, no. 1 (2019): 15–21. http://dx.doi.org/10.32734/st.v2i1.306.

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Pembuatan lemak margarin melalui interesterifikasi dalam industri merupakan suatu proses yang dapat digunakan menggantikan proses blendingan dan hidrogenasi. Salah satu faktor yang mempengaruhi proses interesterifikasi adalah suhu pemanasan. Dalam penelitian ini dilakukan pembuatan lemak margarin melalui proses interesterifikasi dari bahan dasar berbasis minyak kelapa sawit yaitu RBDPO dan RBDPS menggunakan katalis NaOCH 3 dan ingin diketahui pengaruh suhu proses interesterifikasi terhadap nilai kandungan lemak padat (SFC) dan komposisi trigliserida dari variasi suhu pada temperatur 70, 90, 11

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Aljabry, Mansour S., Fahad Alabbas, Ghaleb Elyamany, et al. "Clinicopathological Features of Rare Bleeding Disorders in High Consanguinity Population; A Retrospective Analysis from Two Tertiary Hospitals in Saudi Arabia." Journal of Applied Hematology 14, no. 2 (2023): 101–7. http://dx.doi.org/10.4103/joah.joah_103_22.

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BACKGROUND: Rare bleeding disorder (RBDs) encompasses a deficiency of one or more of FXIII, FXI, FX, FVII, FV, FII, and FI clotting factors, leading to bleeding disorders with variable presentations and outcomes ranging from none or minimal to life-threatening events. RBDs are still underdiagnosed and underreported, especially in Saudi population with a high prevalence of consanguinity. OBJECTIVES: The study aimed to determine the frequency of RBDs, grading of their bleeding severity, and assessment of clinical manifestations and management of RBDs in tertiary Saudi Arabian hospitals. DESIGN A

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Sen, Ankita, Prakas K. Mandal, Sumit Mitra, et al. "An account of congenital rare bleeding disorders: a systematic study from a tertiary care centre in Eastern India." International Journal of Advances in Medicine 7, no. 7 (2020): 1131. http://dx.doi.org/10.18203/2349-3933.ijam20202589.

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Background: Rarity of rare bleeding disorders (RBDs) is attributed to very low incidence based on ethnicity, distribution and complexity of diagnostic tools. There is scarcity of data on RBDs from Eastern India. This study aims to understand the distribution of RBDs in this region for better patient care.Methods: Retrospective study conducted on patients presented with symptoms/signs of bleeding from January 2018 to December 2019 (two years). Patients having bleeding manifestations from causes other than inherited coagulation disorders, IPDs, and vWD were included. Complete haemogram, peripher

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Burd, C. G., E. L. Matunis, and G. Dreyfuss. "The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities." Molecular and Cellular Biology 11, no. 7 (1991): 3419–24. http://dx.doi.org/10.1128/mcb.11.7.3419-3424.1991.

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The poly(A)-binding protein (PABP) is the major mRNA-binding protein in eukaryotes, and it is essential for viability of the yeast Saccharomyces cerevisiae. The amino acid sequence of the protein indicates that it consists of four ribonucleoprotein consensus sequence-containing RNA-binding domains (RBDs I, II, III, and IV) and a proline-rich auxiliary domain at the carboxyl terminus. We produced different parts of the S. cerevisiae PABP and studied their binding to poly(A) and other ribohomopolymers in vitro. We found that none of the individual RBDs of the protein bind poly(A) specifically or

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Burd, C. G., E. L. Matunis, and G. Dreyfuss. "The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities." Molecular and Cellular Biology 11, no. 7 (1991): 3419–24. http://dx.doi.org/10.1128/mcb.11.7.3419.

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The poly(A)-binding protein (PABP) is the major mRNA-binding protein in eukaryotes, and it is essential for viability of the yeast Saccharomyces cerevisiae. The amino acid sequence of the protein indicates that it consists of four ribonucleoprotein consensus sequence-containing RNA-binding domains (RBDs I, II, III, and IV) and a proline-rich auxiliary domain at the carboxyl terminus. We produced different parts of the S. cerevisiae PABP and studied their binding to poly(A) and other ribohomopolymers in vitro. We found that none of the individual RBDs of the protein bind poly(A) specifically or

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Şalcıoğlu, Zafer, Cengiz Bayram, Hülya Şen, et al. "Congenital Factor Deficiencies in Children: A Report of a Single-Center Experience." Clinical and Applied Thrombosis/Hemostasis 24, no. 6 (2017): 901–7. http://dx.doi.org/10.1177/1076029617731596.

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Congenital factor deficiencies (CFDs) refer to inherited deficiency of coagulation factors in the blood. A total of 481 patients with CFDs, who were diagnosed and followed at our Pediatric Hematology and Oncology Clinic between 1990 and 2015, were retrospectively evaluated. Of the 481 cases, 134 (27.8%) were hemophilia A, 38 (7.9%) were hemophilia B, 57 (11.8%) were von Willebrand disease (vWD), and 252 (52.3%) were rare bleeding disorders (RBDs). The median age of the patients at the time of diagnosis and at the time of the study was 4.1 years (range: 2 months to 20.4 years) and 13.4 years (r

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Miner-Romanoff, Karen, Yuerong Sweetland, Yi Yang, and Barbara Fennema. "Assessment of Professional Development and Research-Based Instructional Strategies for Instructors of Online Undergraduate STEM Courses." International Journal of Online Pedagogy and Course Design 9, no. 1 (2019): 51–61. http://dx.doi.org/10.4018/ijopcd.2019010104.

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Professional development (PD) programs for faculty are critical for improvement of STEM instruction. Little research exists on the impact of such programs in the online environment. This article reports the pilot study results of an observation protocol (OP) on the development of an online PD program for STEM faculty grounded in research-based instructional strategies (RBIS) and the development plan for the program. The RBIS-based OP in place at Franklin University will be used to identify and assess online STEM instructors' teaching practices before and after the PD program. Pilot study resul

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Breunig, H. J., L. Balázs, N. Philipp, A. Soran, and C. Silvestru. "ORGANOBISMUTH HOMOCYCLES (RBi)n AND HETEROCYCLES (RBiS)2." Phosphorus, Sulfur, and Silicon and the Related Elements 179, no. 4-5 (2004): 853–57. http://dx.doi.org/10.1080/10426500490427349.

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Muleya, Victor, and Claudius Marondedze. "Functional Roles of RNA-Binding Proteins in Plant Signaling." Life 10, no. 11 (2020): 288. http://dx.doi.org/10.3390/life10110288.

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RNA-binding proteins (RBPs) are typical proteins that bind RNA through single or multiple RNA-binding domains (RBDs). These proteins have a functional role in determining the fate or function of the bound RNAs. A few hundred RBPs were known through in silico prediction based on computational assignment informed by structural similarity and the presence of classical RBDs. However, RBPs lacking such conventional RBDs were omitted. Owing to the recent mRNA interactome capture technology based on UV-crosslinking and fixing proteins to their mRNA targets followed by affinity capture purification an

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Lestari, Puji, Faisal Yusuf, and Mainal Furqan. "Iodine value analysis on RBD palm olein and RBD palm stearin." Journal of Midwifery and Nursing 7, no. 1 (2025): 79–83. https://doi.org/10.35335/jmn.v7i1.5927.

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Studies and analyses were made to determine the degree of uncertainty in the iodine value estimation of refined, bleached, and deodorized (RBD) palm oil and after fractination (RBD palm olein and RBD palm stearin). At refining process and produce Refined Bleached Deodorized Palm Oil (RBDPO), enter the fractionation process will produce RBD palm olein (RBDPL) and RBD palm stearin (RBDPS). A commonly used metric to assess the quality of vegetable oils is the iodine value (IV). The main objective is to observe IV of RBDPL and RBDPS after fractination process. The approved AOCS Cd 1–25 technique w

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Loreño, Dustin, and Joviel Teves. "Determinants of Repayment Performance of Agricultural Loans Clients of RBDI, Abuyog Branch." International Journal of Research in Vocational Studies (IJRVOCAS) 3, no. 3 (2023): 16–27. http://dx.doi.org/10.53893/ijrvocas.v3i3.213.

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The study aimed to present the profile of the agricultural loan clients of RBDI, describe the loan assessment process, describe the loan monitoring process in RBDI, identify the determinants of loan repayment performance of RBDI agricultural loan clients and to recommend courses of action to improve loan application assessment, loan monitoring, and loan collection activities of RBDI. The study used the Logit Regression Analysis and the model Y = β0 + β1X1 + β2X2 + β3X3 + β4X4 + . . . . . . . βnXn + e was developed. The binary response is non-payment (default) and payment (non-default). The det

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Palla, Roberta, Flora Peyvandi, and Amy D. Shapiro. "Rare bleeding disorders: diagnosis and treatment." Blood 125, no. 13 (2015): 2052–61. http://dx.doi.org/10.1182/blood-2014-08-532820.

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Abstract Despite the worldwide prevalence of rare bleeding disorders (RBDs), knowledge of these conditions and their management is suboptimal; health care professionals often have little diagnostic and treatment experience with variable access to diagnostic modalities required for accurate identification. Therefore, patients often experience morbidity and mortality due to delayed diagnosis. As RBDs represent a small potential commercial market, few, if any, specific therapies exist for these conditions. As a result, affected individuals commonly face delayed diagnosis, incomplete laboratory ev

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Sapam, Sobita, and Bikas Kumar Sinha. "Analysis of Mixed Effects Model for Randomized Block Designs with Both-sided Neighbor-Effects." International Journal of Statistical Sciences 23, no. 2 (2023): 19–30. http://dx.doi.org/10.3329/ijss.v23i2.70128.

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In this study we confine our attention to Randomized Block Designs (RBDs) with random block effects in the presence of both-sided neighbor-effects and focus our attention to (i) estimation of variance components, and (ii) estimation of treatment contrasts as well as both left-sided and right sided neighbor-effects contrasts. We start with a simple set-up of 4 blocks and 4 treatments in an RBD. This we do by concurrently studying three distinct RBDs with the same parameters. However, the allocations of Left Neighbor (LN)- and Right Neighbor (RN)-Effects are assumed to be different across the RB

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Silwal, Umesh, and Rudra Kafle. "Evidence-based Teaching Practices in Physics: An Overview on Authentic Teaching and Learning." Journal of Nepal Physical Society 10, no. 1 (2024): 37–48. https://doi.org/10.3126/jnphyssoc.v10i1.72834.

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Learning is inherently a social process as outlined by the theory of constructivism. Learners construct knowledge via active participation and experience. Meaningful learning requires multiple means of engagement, representation of materials, and assessment. The current challenges in physics teaching-learning are understanding of the learning mechanism, designing of proper instructional materials, and use of student-engagement strategies that help them in long-term retention of the concepts. Pedagogical research shows that the teaching-learning process should be learner-centered where the lear

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Schwob, P. R. "An in-receiver database-the critical factor in RBDS." IEEE Transactions on Consumer Electronics 39, no. 3 (1993): 442–47. http://dx.doi.org/10.1109/30.234618.

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Shamoo, Yousif, Norzehan Abdul-Manan, and Kenneth R. Williams. "Multiple RNA binding domains (RBDs) just don't add up." Nucleic Acids Research 23, no. 5 (1995): 725–28. http://dx.doi.org/10.1093/nar/23.5.725.

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Iriani, Yulidia, Yan Ramona, and Ni Putu Adriani Astiti. "Potensi Ekstrak Ethanol Daun Salam Dan Air Rebusan Daun Salam Untuk Memperbaiki Profil Lipid (Ldl-Kolesterol) Darah Pada Tikus Wistar." Metamorfosa: Journal of Biological Sciences 8, no. 1 (2021): 89. http://dx.doi.org/10.24843/metamorfosa.2021.v08.i01.p09.

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Hyperlipidimia merupakan suatu penyakit/kelainan terkait kardiovascular yang banyak dijumpai, dan jumlah penderitanya cenderung mengalami peningkatan. Kelainan ini disebabkan oleh pola makan masyarakat yang cenderung mengkonsumsi makanan tinggi lemak, tetapi rendah kadar serat. Pemakaian obat paten, seperti simvastatin merupakan pilihan utama saat ini untuk mengatasi masalah tersebut. Namun, pemakaian obat ini dalam waktu lama tidak dianjurkan, sehingga perlu dicari bahan alam yang mempunyai efek sama dengan obat tersebut. Pada penelitian ini, daun salam (Sizygium polyanthum [Wight] Walp) diuj

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Karimi, Mehran, Hassan Mohtadi, Sezaneh Haghpanah, and Mahboobeh Akbari. "Quality of Life in Children with Rare Bleeding Disorders." Blood 126, no. 23 (2015): 4698. http://dx.doi.org/10.1182/blood.v126.23.4698.4698.

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Abstract Background: Patients with rare bleeding disorders (RBDs) face with several problems due to the chronic feature of the disease. So their physical and mental health is affected. Objective: The aim of this study is to evaluate quality of life (QOL) in patients with RBDs using haemo-QOL questionnaire. Methods: In this cross-sectional study, 52 consecutive children aged between4-18 years old with RBDs registered at the Haemophila center of Fars province in Southern Iran were investigated from January to April 2015. Quality of life was evaluated by expert nurses using haemo-QOL questionnair

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Mustafa, Mansoor, and Muhammad Omer Farooq Malik. "Factors Hindering Solar Photovoltaic System Implementation in Buildings and Infrastructure Projects: Analysis through a Multiple Linear Regression Model and Rule-Based Decision Support System." Buildings 13, no. 7 (2023): 1786. http://dx.doi.org/10.3390/buildings13071786.

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Energy plays a predominant role in the development of society. With advancements in technology and the growth of society (buildings and infrastructures), the demand for energy is rapidly increasing. Developing countries typically rely on the import of fossil fuels and capital investments in infrastructure development to meet their energy needs. The execution of solar PV projects in developing countries is currently not being implemented promisingly. Therefore, the determination of the critical success factors hindering the implementation of solar PV projects is the need of the hour. The aim of

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Luo, Deyan, Xuechao Liu, Li Xing, et al. "Immunogenicity and Protection from Receptor-Binding Domains of Toxins as Potential Vaccine Candidates for Clostridium difficile." Vaccines 7, no. 4 (2019): 180. http://dx.doi.org/10.3390/vaccines7040180.

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The receptor-binding domains (RBDs) located in toxin A and toxin B of Clostridium difficile are known to be nontoxic and immunogenic. We need to develop a new type vaccine based on RBDs. In this study, we expressed and purified recombinant proteins (named RBD-TcdA and RBD-TcdB) as vaccine candidates containing the RBDs of toxin A and toxin B, respectively, from the C. difficile reference strain VPI10463. The immunogenicity and protection of the vaccine candidates RBD-TcdA, RBD-TcdB, and RBD-TcdA/B was evaluated by ELISA and survival assays. The data indicated that mice immunized with all vacci

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Tsamesidis, Ioannis, Evangelia Stalika, Chinedu O. Egwu, et al. "The Potential Impact of Blood System on Dietary Habits and Smoking." Medicines 9, no. 1 (2022): 3. http://dx.doi.org/10.3390/medicines9010003.

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The ‘Blood-Type’ diet advises individuals to eat according to their ABO blood group to improve their health and decrease the risk of chronic diseases. However, the food preferences of individuals with different blood groups have not been examined. The aim of our study was to investigate, in healthy regular blood donors (rBDs), the associations of smoke, alcohol, caffeine, vitamin and fat intake with their different blood groups and if ABO groups could be a potential predictor tool for disease prevention. A total of 329 volunteers were divided into four groups according to their ABO types: Grou

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Wang, Zhengguang, Zhihan Yang, Mami Shishido, et al. "Microcystis viridis NIES-102 Cyanobacteria Lectin (MVL) Interacts with SARS-CoV-2 Spike Protein Receptor Binding Domains (RBDs) via Protein–Protein Interaction." International Journal of Molecular Sciences 25, no. 12 (2024): 6696. http://dx.doi.org/10.3390/ijms25126696.

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The emergence of coronavirus disease 2019 (COVID-19) posed a major challenge to healthcare systems worldwide, especially as mutations in the culprit Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) complicated the development of vaccines and antiviral drugs. Therefore, the search for natural products with broad anti-SARS-CoV-2 capabilities is an important option for the prevention and treatment of similar infectious diseases. Lectins, which are widely recognized as antiviral agents, could contribute to the development of anti-SARS-CoV-2 drugs. This study evaluated the binding affin

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Nancy, S. Gilbert, and N. Nischala. "RBIDS- IDS with Biometric Authentication and Trace Back Scheme for Enhanced Security." International Journal of Computer Applications 1, no. 3 (2010): 44–49. http://dx.doi.org/10.5120/87-186.

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Aksenova, Anna Y., Ilya V. Likhachev, Sergei Y. Grishin, and Oxana V. Galzitskaya. "The Increased Amyloidogenicity of Spike RBD and pH-Dependent Binding to ACE2 May Contribute to the Transmissibility and Pathogenic Properties of SARS-CoV-2 Omicron as Suggested by In Silico Study." International Journal of Molecular Sciences 23, no. 21 (2022): 13502. http://dx.doi.org/10.3390/ijms232113502.

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SARS-CoV-2 is a rapidly evolving pathogen that has caused a global pandemic characterized by several consecutive waves. Based on epidemiological and NGS data, many different variants of SARS-CoV-2 were described and characterized since the original variant emerged in Wuhan in 2019. Notably, SARS-CoV-2 variants differ in transmissibility and pathogenicity in the human population, although the molecular basis for this difference is still debatable. A significant role is attributed to amino acid changes in the binding surface of the Spike protein to the ACE2 receptor, which may facilitate virus e

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BARGHOUTI, NASER S., and GAIL E. KAISER. "SCALING UP RULE-BASED SOFTWARE DEVELOPMENT ENVIRONMENTS." International Journal of Software Engineering and Knowledge Engineering 02, no. 01 (1992): 59–78. http://dx.doi.org/10.1142/s021819409200004x.

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Rule-based software development environments (RBDEs) model the software development process in terms of rules that encapsulate development activities, and assist in executing the process via forward and backward chaining over the rule base. We investigate the scaling up of RBDEs to support (1) multiple views of the rule base for multiple users and (2) evolution of the rule base over the lifetime of a project. Our approach is based on clarifying two distinct functions of rules and chaining: maintaining consistency and automation. By definition, consistency is mandatory whereas automation is not

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Drews, R. "Evolution of ice-shelf channels in Antarctic ice shelves." Cryosphere 9, no. 3 (2015): 1169–81. http://dx.doi.org/10.5194/tc-9-1169-2015.

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Abstract. Ice shelves buttress the continental ice flux and mediate ice–ocean interactions. They are often traversed by channels in which basal melting is enhanced, impacting ice-shelf stability. Here, channel evolution is investigated using a transient, three-dimensional full Stokes model and geophysical data collected on the Roi Baudouin Ice Shelf (RBIS), Antarctica. The modeling confirms basal melting as a feasible mechanism for channel creation, although channels may also advect without melting for many tens of kilometers. Channels can be out of hydrostatic equilibrium depending on their w

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Drews, R. "Evolution of ice-shelf channels in Antarctic ice shelves." Cryosphere Discussions 9, no. 2 (2015): 1603–31. http://dx.doi.org/10.5194/tcd-9-1603-2015.

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Abstract. Ice shelves buttress the continental ice flux and mediate ice–ocean interactions. They are often traversed by channels in which basal melting is enhanced, impacting ice-shelf stability. Here, channel evolution is investigated using a transient, three-dimensional full Stokes model and geophysical data collected on Roi Baudouin Ice Shelf (RBIS), Antarctica. The modeling confirms basal melting as a feasible mechanism for channel creation, although channels may also advect without melting for many tens of kilometers. Channels can be out of hydrostatic equilibrium depending on their width

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Gotor, Nieves Lorenzo, Alexandros Armaos, Giulia Calloni, et al. "RNA-binding and prion domains: the Yin and Yang of phase separation." Nucleic Acids Research 48, no. 17 (2020): 9491–504. http://dx.doi.org/10.1093/nar/gkaa681.

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Abstract Proteins and RNAs assemble in membrane-less organelles that organize intracellular spaces and regulate biochemical reactions. The ability of proteins and RNAs to form condensates is encoded in their sequences, yet it is unknown which domains drive the phase separation (PS) process and what are their specific roles. Here, we systematically investigated the human and yeast proteomes to find regions promoting condensation. Using advanced computational methods to predict the PS propensity of proteins, we designed a set of experiments to investigate the contributions of Prion-Like Domains

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Sun, Qiyue. "Preservation and renewal of historical and cultural blocks under urban RBD model: A case study of Baoding West Street." E3S Web of Conferences 553 (2024): 04006. http://dx.doi.org/10.1051/e3sconf/202455304006.

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Preservation and renewal of historical and cultural blocks is an important part of the urban renewal process. At present, China pays more and more attention to the protection of historical and cultural blocks, how to make historical and cultural blocks revitalized in modern cities is a problem worth thinking about. The urban RBD model provides new ideas for the protection and renewal of historical and cultural blocks. This paper intends to summarize the development and characteristics of the urban RBD model by using the literature research method and the field research method, conduct case stu

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Peyvandi, Flora, and Marzia Menegatti. "Treatment of rare factor deficiencies in 2016." Hematology 2016, no. 1 (2016): 663–69. http://dx.doi.org/10.1182/asheducation-2016.1.663.

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Abstract Rare bleeding disorders (RBDs) are a heterogeneous group of coagulation disorders characterized by fibrinogen, prothrombin, factors V, VII, X, XI, or XIII (FV, FVII, FX, FXI, or FXIII, respectively), and the combined factor V + VIII and vitamin K–dependent proteins deficiencies, representing roughly 5% of all bleeding disorders. They are usually transmitted as autosomal, recessive disorders, and the prevalence of the severe forms could range from 1 case in 500 000 for FVII up to 1 in 2-3 million for FXIII in the general population. Patients affected with RBDs may present a wide range

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Niu, Xiaoyu, Yixuan J. Hou, Kwonil Jung, Fanzhi Kong, Linda J. Saif, and Qiuhong Wang. "Chimeric Porcine Deltacoronaviruses with Sparrow Coronavirus Spike Protein or the Receptor-Binding Domain Infect Pigs but Lose Virulence and Intestinal Tropism." Viruses 13, no. 1 (2021): 122. http://dx.doi.org/10.3390/v13010122.

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Porcine deltacoronavirus (PDCoV) strain OH-FD22 infects poultry and shares high nucleotide identity with sparrow-origin deltacoronaviruses (SpDCoV) ISU73347 and HKU17 strains. We hypothesized that the spike (S) protein or receptor-binding domain (RBD) from these SpDCoVs would alter the host and tissue tropism of PDCoV. First, an infectious cDNA clone of PDCoV OH-FD22 strain (icPDCoV) was generated and used to construct chimeric icPDCoVs harboring the S protein of HKU17 (icPDCoV-SHKU17) or the RBD of ISU73347 (icPDCoV-RBDISU). To evaluate their pathogenesis, neonatal gnotobiotic pigs were inocu

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Yan, Fang-Fang, and Feng Gao. "Comparison of the binding characteristics of SARS-CoV and SARS-CoV-2 RBDs to ACE2 at different temperatures by MD simulations." Briefings in Bioinformatics 22, no. 2 (2021): 1122–36. http://dx.doi.org/10.1093/bib/bbab044.

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Abstract Temperature plays a significant role in the survival and transmission of SARS-CoV (severe acute respiratory syndrome coronavirus) and SARS-CoV-2. To reveal the binding differences of SARS-CoV and SARS-CoV-2 receptor-binding domains (RBDs) to angiotensin-converting enzyme 2 (ACE2) at different temperatures at atomic level, 20 molecular dynamics simulations were carried out for SARS-CoV and SARS-CoV-2 RBD–ACE2 complexes at five selected temperatures, i.e. 200, 250, 273, 300 and 350 K. The analyses on structural flexibility and conformational distribution indicated that the structure of

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Zhao, Fei, Yang Xin, Kai Zhang, and Xinxin Niu. "Representativeness-Based Instance Selection for Intrusion Detection." Security and Communication Networks 2021 (March 12, 2021): 1–13. http://dx.doi.org/10.1155/2021/6638134.

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With the continuous development of network technology, an intrusion detection system needs to face detection efficiency and storage requirement when dealing with large data. A reasonable way of alleviating this problem is instance selection, which can reduce the storage space and improve intrusion detection efficiency by selecting representative instances. An instance is representative not only in its class but also in different classes. This representativeness reflects the importance of an instance. Since the existing instance selection algorithm does not take into account the above situation

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Austin, Publishing Group. "Clinical Profile and Bleeding Outcome of Pediatric Rare Bleeding Disorders: The Royal Hospital's Experience, Oman." Journal of Blood Disorders 10, no. 2 (2023): 1076. https://doi.org/10.26420/jblooddisordl.2023.1076.

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Abstract <strong>Introduction:</strong> Rare Bleeding Disorders (RBDs), a group of inherited coagulation factor deficiencies, are more common in areas with a high rate of consanguineous marriages. Data on the frequency and outcome of RBDs among children in Oman are limited. <strong>Aim:</strong> This study evaluated the clinical profile and bleeding outcomes of paediatric RBDs at the Royal Hospital, the largest referring centre in Oman, from 2010 to 2020. <strong>Methods:</strong> This retrospective descriptive cohort study includes all Omani children, less than 13 years of age,

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Ginting, Mimpin, Herlince Sihotang, and Willem Prodis Singarimbun. "Analisis Perubahan Kandungan Lemak Padat , Asam Lemak Trans Dan Komposisi Trigliserida Pada Pembuatan Lemak Pengganti Mentega Coklat Melalui Metode Blending Dibandingkan Interesterifikasi RBDPS Dengan RBDPKO." Talenta Conference Series: Science and Technology (ST) 1, no. 1 (2018): 094–100. http://dx.doi.org/10.32734/st.v1i1.195.

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Lemak pengganti mentega coklat (CBS) dalam industri dapat dihasilkan melalui proses hidrogenasi parsial minyak cair, blending maupun interesterifikasi lemak padat dan minyak cair. Nilai kandungan asam lemak trans (TFA) dan kandungan lemak padat (SFC) merupakan parameter yang penting diuji dalam memenuhi kwalitas dari lemak tersebut sebagai edible oil. Dalam penelitian ini dilakukan metode blending dibandingkan dengan interesterifikasi menggunakan katalis natrium metoksida antara lemak padat RBDPS dengan RBDPKO pada rasio 90:10, 80:20, 70:30, 60:40, 50:50, 40:60, 30:70, 20:80 dan 10:80 (b/b) un

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Carnevali, Laura, Lorenzo Ciani, Alessandro Fantechi, Gloria Gori, and Marco Papini. "An Efficient Library for Reliability Block Diagram Evaluation." Applied Sciences 11, no. 9 (2021): 4026. http://dx.doi.org/10.3390/app11094026.

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Reliability Block Diagrams (RBDs) are widely used in reliability engineering to model how the system reliability depends on the reliability of components or subsystems. In this paper, we present librbd, a C library providing a generic, efficient and open-source solution for time-dependent reliability evaluation of RBDs. The library has been developed as a part of a project for reliability evaluation of complex systems through a layered approach, combining different modeling formalisms and solution techniques at different system levels. The library achieves accuracy and efficiency comparable to

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Lundkvist, Pär, Sara Jupiter, Åsa Segerstolpe, Yvonne N. Osheim, Ann L. Beyer, and Lars Wieslander. "Mrd1p Is Required for Release of Base-Paired U3 snoRNA within the Preribosomal Complex." Molecular and Cellular Biology 29, no. 21 (2009): 5763–74. http://dx.doi.org/10.1128/mcb.00428-09.

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ABSTRACT In eukaryotes, ribosomes are made from precursor rRNA (pre-rRNA) and ribosomal proteins in a maturation process that requires a large number of snoRNPs and processing factors. A fundamental problem is how the coordinated and productive folding of the pre-rRNA and assembly of successive pre-rRNA-protein complexes is achieved cotranscriptionally. The conserved protein Mrd1p, which contains five RNA binding domains (RBDs), is essential for processing events leading to small ribosomal subunit synthesis. We show that full function of Mrd1p requires all five RBDs and that the RBDs are funct

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