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1

Zadrag-Tecza, Renata, Magdalena Kwolek-Mirek, Małgorzata Alabrudzińska, and Adrianna Skoneczna. "Cell Size Influences the Reproductive Potential and Total Lifespan of theSaccharomyces cerevisiaeYeast as Revealed by the Analysis of Polyploid Strains." Oxidative Medicine and Cellular Longevity 2018 (2018): 1–17. http://dx.doi.org/10.1155/2018/1898421.

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The total lifespan of the yeastSaccharomyces cerevisiaemay be divided into two phases: the reproductive phase, during which the cell undergoes mitosis cycles to produce successive buds, and the postreproductive phase, which extends from the last division to cell death. These phases may be regulated by a common mechanism or by distinct ones. In this paper, we proposed a more comprehensive approach to reveal the mechanisms that regulate both reproductive potential and total lifespan in cell size context. Our study was based on yeast cells, whose size was determined by increased genome copy numbe
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Vidane, Atanásio S., Helena D. Zomer, Bruna M. M. Oliveira, et al. "Reproductive Stem Cell Differentiation." Reproductive Sciences 20, no. 10 (2013): 1137–43. http://dx.doi.org/10.1177/1933719113477484.

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Boddy, Amy M., Hanna Kokko, Felix Breden, Gerald S. Wilkinson, and C. Athena Aktipis. "Cancer susceptibility and reproductive trade-offs: a model of the evolution of cancer defences." Philosophical Transactions of the Royal Society B: Biological Sciences 370, no. 1673 (2015): 20140220. http://dx.doi.org/10.1098/rstb.2014.0220.

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The factors influencing cancer susceptibility and why it varies across species are major open questions in the field of cancer biology. One underexplored source of variation in cancer susceptibility may arise from trade-offs between reproductive competitiveness (e.g. sexually selected traits, earlier reproduction and higher fertility) and cancer defence. We build a model that contrasts the probabilistic onset of cancer with other, extrinsic causes of mortality and use it to predict that intense reproductive competition will lower cancer defences and increase cancer incidence. We explore the tr
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Kustan, Jacqueline M., Karen P. Maruska, and Russell D. Fernald. "Subordinate male cichlids retain reproductive competence during social suppression." Proceedings of the Royal Society B: Biological Sciences 279, no. 1728 (2011): 434–43. http://dx.doi.org/10.1098/rspb.2011.0997.

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Subordinate males, which are excluded from reproduction often save energy by reducing their investment in sperm production. However, if their position in a dominance hierarchy changes suddenly they should also rapidly attain fertilization capability. Here, we asked how social suppression and ascension to dominance influences sperm quality, spermatogenesis and reproductive competence in the cichlid Astatotilapia burtoni , where reproduction is tightly coupled to social status. Dominant territorial (T) males are reproductively active while subordinate non-territorial (NT) males are suppressed, b
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Carrithers, Bria, Rachel Klein, and Julie Kanter. "Addressing Reproductive Education Among Young Adults with Sickle Cell Disease (SCD): Sickle Cell Reproductive Outreach and Education (ROE) Project." Blood 142, Supplement 1 (2023): 3903. http://dx.doi.org/10.1182/blood-2023-190927.

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Background: As children with sickle cell disease (SCD) survive into adulthood, it is important to address emerging reproductive health concerns. This population faces unique fertility challenges, including balancing the desire for biological parenthood, risk of pregnancy-associated complications, unintended pregnancy, and fertility concerns with the use of SCD modifying therapies (DMTs) (Smith-Whitley, Blood, 2014, Pecker, Br J Haematol, 2021) . Recent research identified knowledge gaps that impact reproductive care for adults with SCD (Carrithers, Frontiers, 2023). To overcome these gaps, we
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Lie, Merete. "Reproductive Images: The Autonomous Cell." Science as Culture 21, no. 4 (2012): 475–96. http://dx.doi.org/10.1080/09505431.2012.679728.

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Mukhopadhyay, Madhura. "Cell atlases for reproductive health." Nature Methods 22, no. 5 (2025): 893. https://doi.org/10.1038/s41592-025-02709-z.

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Templeman, Nicole M., and Coleen T. Murphy. "Regulation of reproduction and longevity by nutrient-sensing pathways." Journal of Cell Biology 217, no. 1 (2017): 93–106. http://dx.doi.org/10.1083/jcb.201707168.

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Nutrients are necessary for life, as they are a crucial requirement for biological processes including reproduction, somatic growth, and tissue maintenance. Therefore, signaling systems involved in detecting and interpreting nutrient or energy levels—most notably, the insulin/insulin-like growth factor 1 (IGF-1) signaling pathway, mechanistic target of rapamycin (mTOR), and adenosine monophosphate-activated protein kinase (AMPK)—play important roles in regulating physiological decisions to reproduce, grow, and age. In this review, we discuss the connections between reproductive senescence and
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Ra, Kihae, Se Chang Park, and Byeong Chun Lee. "Female Reproductive Aging and Oxidative Stress: Mesenchymal Stem Cell Conditioned Medium as a Promising Antioxidant." International Journal of Molecular Sciences 24, no. 5 (2023): 5053. http://dx.doi.org/10.3390/ijms24055053.

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The recent tendency to delay pregnancy has increased the incidence of age-related infertility, as female reproductive competence decreases with aging. Along with aging, a lowered capacity of antioxidant defense causes a loss of normal function in the ovaries and uterus due to oxidative damage. Therefore, advancements have been made in assisted reproduction to resolve infertility caused by reproductive aging and oxidative stress, following an emphasis on their use. The application of mesenchymal stem cells (MSCs) with intensive antioxidative properties has been extensively validated as a regene
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Wocławek-Potocka, Izabela, Paulina Rawińska, Ilona Kowalczyk-Zieba, et al. "Lysophosphatidic Acid (LPA) Signaling in Human and Ruminant Reproductive Tract." Mediators of Inflammation 2014 (2014): 1–14. http://dx.doi.org/10.1155/2014/649702.

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Lysophosphatidic acid (LPA) through activating its G protein-coupled receptors (LPAR 1–6) exerts diverse cellular effects that in turn influence several physiological processes including reproductive function of the female. Studies in various species of animals and also in humans have identified important roles for the receptor-mediated LPA signaling in multiple aspects of human and animal reproductive tract function. These aspects range from ovarian and uterine function, estrous cycle regulation, early embryo development, embryo implantation, decidualization to pregnancy maintenance and partu
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Soygur, Bikem, and Leyla Sati. "The role of syncytins in human reproduction and reproductive organ cancers." Reproduction 152, no. 5 (2016): R167—R178. http://dx.doi.org/10.1530/rep-16-0031.

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Human life begins with sperm and oocyte fusion. After fertilization, various fusion events occur during human embryogenesis and morphogenesis. For example, the fusion of trophoblastic cells constitutes a key process for normal placental development. Fusion in the placenta is facilitated by syncytin 1 and syncytin 2. These syncytins arose from retroviral sequences that entered the primate genome 25 million and more than 40 million years ago respectively. About 8% of the human genome consists of similar human endogenous retroviral (HERVs) sequences. Many are inactive because of mutations or dele
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Zhang, Xuelian, Mengyang Zhang, Chunzhi Wang, et al. "CPF Induces GC2spd Cell Injury via ROS/AKT/Efcab6 Pathway." Cells 14, no. 13 (2025): 940. https://doi.org/10.3390/cells14130940.

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Chlorpyrifos (CPF) has been extensively utilized in recent decades due to its highly efficient insecticidal properties. However, the widespread use of pesticides has posed new challenges to male reproduction. This study aims to explore the potential molecular mechanisms of male reproductive decline induced by CPF. We employ flow cytometry, qRT-PCR, Western blot, RNA sequencing, and bioinformatics analysis to investigate the potential molecular mechanisms involved in CPF-induced male reproductive damage in GC2spd cells. Our results revealed that after 24 h of CPF treatment, the cell viability,
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Pei, Jie, Lin Xiong, Shaoke Guo, et al. "Single-Cell Transcriptomics Analysis Reveals a Cell Atlas and Cell Communication in Yak Ovary." International Journal of Molecular Sciences 24, no. 3 (2023): 1839. http://dx.doi.org/10.3390/ijms24031839.

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Yaks (Bos grunniens) are the only bovine species that adapt well to the harsh high-altitude environment in the Qinghai-Tibetan plateau. However, the reproductive adaptation to the climate of the high elevation remains to be elucidated. Cell composition and molecular characteristics are the foundation of normal ovary function which determines reproductive performance. So, delineating ovarian characteristics at a cellular molecular level is conducive to elucidating the mechanism underlying the reproductive adaption of yaks. Here, the single-cell RNA-sequencing (scRNA-seq) was employed to depict
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Renuka, Hada1 Rohit Sharma2. "Reproductive Cloning." Science World a monthly e magazine 2, no. 10 (2022): 1642–45. https://doi.org/10.5281/zenodo.7216256.

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The term cloning describes a number of different processes that can be used to produce genetically identical copies of a biological entity. It refers to the transfer of somatic cell&rsquo;s nucleus into an ovum, which then grows into an embryo. The copied material, which has the same genetic makeup as the original, is referred to as a clone<strong>. </strong>Reproductive cloning&nbsp;is defined as the deliberate production of genetically identical individuals. Each newly produced individual is a clone of the original. Monozygotic (identical) twins are natural clones. Clones contain identical s
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M, Hitit. "Putative Role of Micro - RNA s i n Female Reproductive Tract." Open Access Journal of Veterinary Science & Research 2, no. 2 (2017): 1–5. http://dx.doi.org/10.23880/oajvsr-16000131.

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Female reproductive tract is composed of ovarium, oviduct, cervix and uterus. Development and function of reproductive tract is dispens a ble for maintenance and achievement of reproduction. Reproductive tract responses to cyclic changes and ovarium hormones which provide optimum conditions for gam e t e movement and development. While the potential influence of pitu i tary and gonadal hormones on reproductive function is clearly understood, the molecular mechanism regulating reproductive tract remains elusive. Although, post - transcriptional gene regulation has critical role in cell differ e
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Renfree, Marilyn B. "WOMEN IN REPRODUCTIVE SCIENCE: Reproduction down under." Reproduction 158, no. 6 (2019): F127—F137. http://dx.doi.org/10.1530/rep-19-0230.

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Australia is home to a unique assembly of mammals – the marsupials and monotremes. Despite this uniqueness, they have been largely ignored by the biomedical scientific community, and yet study of marsupials has contributed to modern research on reproduction, development, evolution, conservation, molecular and comparative genomics. My lifetime passion for these long-neglected Australian fauna has led to unexpected discoveries and insights that challenged assumptions and opened up new areas of international research. I used a range of disciplinary expertise to pursue the study of these unique ma
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Issigonis, Melanie, Akshada B. Redkar, Tania Rozario, et al. "A Krüppel-like factor is required for development and regeneration of germline and yolk cells from somatic stem cells in planarians." PLOS Biology 20, no. 7 (2022): e3001472. http://dx.doi.org/10.1371/journal.pbio.3001472.

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Sexually reproducing animals segregate their germline from their soma. In addition to gamete-producing gonads, planarian and parasitic flatworm reproduction relies on yolk cell–generating accessory reproductive organs (vitellaria) supporting development of yolkless oocytes. Despite the importance of vitellaria for flatworm reproduction (and parasite transmission), little is known about this unique evolutionary innovation. Here, we examine reproductive system development in the planarian Schmidtea mediterranea, in which pluripotent stem cells generate both somatic and germ cell lineages. We sho
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Liu, Hong-Bo, Pei-Ru Lv, Ruo-Gang He, et al. "Cloned Guangxi Bama Minipig (Sus scrofa) and Its Offspring Have Normal Reproductive Performance." Cellular Reprogramming 12, no. 5 (2010): 543–50. http://dx.doi.org/10.1089/cell.2009.0094.

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Tucker, Emily K., Megan E. Zurliene, Cory D. Suski, and Romana A. Nowak. "Gonad development and reproductive hormones of invasive silver carp (Hypophthalmichthys molitrix) in the Illinois River." Biology of Reproduction 102, no. 3 (2019): 647–59. http://dx.doi.org/10.1093/biolre/ioz207.

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Abstract Reproduction is a major component of an animal’s life history strategy. Species with plasticity in their reproductive biology are likely to be successful as an invasive species, as they can adapt their reproductive effort during various phases of a biological invasion. Silver carp (Hypophthalmicthys molitrix), an invasive cyprinid in North America, display wide variation in reproductive strategies across both their native and introduced ranges, though the specifics of silver carp reproduction in the Illinois River have not been established. We assessed reproductive status using histol
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Pertiwi, Putu Dewi Diah, Ida Arimurti Sanjiwani, and Ni Kadek Ayu Suarningsih. "A, Adolescent The Relations between Parenting Styles with Adolescent Reproductive Health Knowledge in Junior High School “X” in Gianyar Regency." Journal of A Sustainable Global South 6, no. 2 (2022): 32. http://dx.doi.org/10.24843/jsgs.2022.v06.i02.p03.

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Adolescence are changes both physically and psychologically. The occurrence of physical changes characterized by changes in reproductive functions and systems causes sexual motivation that makes adolescents vulnerable to diseases and reproductive health problems. Adolescents are expected to have good reproductive health knowledge to avoid various reproductive health problems. Knowledge of reproductive health is influenced by several factors, such as parenting styles. Parents have a big role in providing supervision and nurturing of teenagers in a family environment. This study aims to determin
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Smith-Whitley, Kim. "Reproductive issues in sickle cell disease." Blood 124, no. 24 (2014): 3538–43. http://dx.doi.org/10.1182/blood-2014-07-577619.

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Abstract As medical advances improve survival, reduce disease-related morbidity, and improve quality of life, reproductive issues will take higher priority in the sickle cell disease (SCD) community. A wide variety of topics are addressed in this chapter, including fertility, gonadal failure, erectile dysfunction, and menstrual issues in SCD. Etiologies of impaired male fertility are multifactorial and include hypogonadism, erectile dysfunction, sperm abnormalities, and complications of medical therapies. Much less is known about the prevalence and etiology of infertility in women with SCD. Ot
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Smith-Whitley, Kim. "Reproductive issues in sickle cell disease." Hematology 2014, no. 1 (2014): 418–24. http://dx.doi.org/10.1182/asheducation-2014.1.418.

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Abstract As medical advances improve survival, reduce disease-related morbidity, and improve quality of life, reproductive issues will take higher priority in the sickle cell disease (SCD) community. A wide variety of topics are addressed in this chapter, including fertility, gonadal failure, erectile dysfunction, and menstrual issues in SCD. Etiologies of impaired male fertility are multifactorial and include hypogonadism, erectile dysfunction, sperm abnormalities, and complications of medical therapies. Much less is known about the prevalence and etiology of infertility in women with SCD. Ot
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Fukui, Atsushi. "NK cell abnormalities and reproductive failures." Journal of Reproductive Immunology 156 (March 2023): 103855. http://dx.doi.org/10.1016/j.jri.2023.103855.

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Moreno, Inmaculada, and Carlos Simon. "Deciphering the effect of reproductive tract microbiota on human reproduction." Reproductive Medicine and Biology 18, no. 1 (2018): 40–50. http://dx.doi.org/10.1002/rmb2.12249.

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Shimasaki, Shunichi, R. Kelly Moore, Fumio Otsuka, and Gregory F. Erickson. "The Bone Morphogenetic Protein System In Mammalian Reproduction." Endocrine Reviews 25, no. 1 (2004): 72–101. http://dx.doi.org/10.1210/er.2003-0007.

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Using molecular, cellular, and genetic approaches, recent studies examining the role of the bone morphogenetic protein (BMP) family of growth factors in the reproductive system have led to significant breakthroughs in our understanding of mammalian reproduction and fertility. Gene expression studies have revealed that key components of the BMP system (ligands, receptors, signaling molecules, and binding proteins) exhibit coordinated spatial and temporal expression patterns in fundamental cell types throughout the reproductive system. Availability of recombinant BMPs has enabled functional stud
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Yan, Zunqiang, Qiaoli Yang, Pengfei Wang, and Shuangbao Gun. "Transcriptional Profiling of Testis Development in Pre-Sexually-Mature Hezuo Pig." Current Issues in Molecular Biology 47, no. 1 (2024): 10. https://doi.org/10.3390/cimb47010010.

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Spermatogenesis is an advanced biological process, relying on intricate interactions between somatic and germ cells in testes. Investigating various cell types is challenging because of cellular heterogeneity. Single-cell RNA sequencing (scRNA-seq) offers a method to analyze cellular heterogeneity. In this research, we performed 10× Genomics scRNA-seq to conduct an unbiased single-cell transcriptomic analysis in Hezuo pig (HZP) testis at one month of age during prepuberty. We collected 14,276 cells and identified 8 cell types (including 2 germ cells types and 6 somatic cell types). Pseudo-timi
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Winship, Amy, Ellen Menkhorst, Michelle Van Sinderen, and Evdokia Dimitriadis. "Interleukin 11: similar or opposite roles in female reproduction and reproductive cancer?" Reproduction, Fertility and Development 28, no. 4 (2016): 395. http://dx.doi.org/10.1071/rd14128.

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During placental development and carcinogenesis, cell invasion and migration are critical events in establishing a self-supporting vascular supply. Interleukin (IL)-11 is a pleiotropic cytokine that affects the invasive and migratory capabilities of trophoblast cells that form the placenta during pregnancy, as well as various malignant cell types. The endometrium is the site of embryo implantation during pregnancy; conversely, endometrial carcinoma is the most common gynaecological malignancy. Here, we review what is known about the role of IL-11 in trophoblast function and in gynaecological m
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Dong, Shucan, Biwei Hou, Chuang Yang, et al. "Comparative Hypothalamic Transcriptome Analysis Reveals Crucial mRNAs, lncRNAs, and circRNAs Affecting Litter Size in Goats." Genes 14, no. 2 (2023): 444. http://dx.doi.org/10.3390/genes14020444.

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Litter size is an important indicator to measure the reproductive performance of goats, which is affected by the reproductive function of animals. The hypothalamus, as the regulatory center of the endocrine system, plays an important role in the reproduction of female animals. Here, we performed high-throughput RNA sequencing using hypothalamic tissue from high-fecundity and low-fecundity Leizhou goats to explore critical functional genes associated with litter size. Differentially expressed mRNA, lncRNA, and circRNAs were screened using DESeq and were enriched, and then analyzed by Gene Ontol
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Bachelot, Anne, and Nadine Binart. "Reproductive role of prolactin." Reproduction 133, no. 2 (2007): 361–69. http://dx.doi.org/10.1530/rep-06-0299.

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The biological actions of prolactin (PRL), a polypeptide hormone, are mostly related to lactation and reproduction. These actions have been clarified by studies of PRL and PRL-deficient receptor mice, which have a clear phenotype of reproductive failure at multiple sites. This review aims to summarize current knowledge about PRL and its receptor, role in reproductive axis and presents information of hyperprolactinemia in reproductive medicine. Our understanding of the physiology and transduction pathway of PRL has largely increased in the past 20 years with the cloning of PRL and its receptor
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Wen, Lixin, Rongfang Li, Ji Wang, and Jine Yi. "The reproductive stress hypothesis." Reproduction 158, no. 6 (2019): R209—R218. http://dx.doi.org/10.1530/rep-18-0592.

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In this paper, we propose the reproductive stress hypothesis that describes the pregnant females response to reproductive events based upon the activation of the hypothalamic–pituitary–adrenal axis and sympathetic adrenomedullary system. The main components of the reproductive stress hypothesis can be summarized as follows: (1) events unique to reproduction including empathema, pregnancy, parturition and lactation cause non-specific responses in females, called active reproductive stress; (2) the fetus is a special stressor for pregnant females where endocrine hormones, including corticotropin
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Li, Xinyi, Peiyi Lin, Zaikuan Zhang, et al. "USO1 Coordinates Centriolar Satellites to Regulate Male Germ Cell Proliferation and Cell Cycle Progression." International Journal of Molecular Sciences 26, no. 9 (2025): 4274. https://doi.org/10.3390/ijms26094274.

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The endoplasmic reticulum–Golgi apparatus system is an important organelle regulating male reproduction. USO1 vesicle transport factor (USO1), as an important molecule in this system, is a general vesicular transport factor and regulates various biological processes in vivo. However, the potential role of USO1 in mammalian testis development and spermatogenesis has not been investigated. We documented the presence of USO1 in mouse germ cells and its functional roles by generating Uso1-knockout germ cell lines. Uso1 depletion suppressed cell proliferation and growth while stimulating apoptosis
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Markova, E., L. Lyulkova, R. Melnik, and V. Popova. "Cultural properties of swine reproductive and respiratory syndrome virus isolate." Agrarian Bulletin of the 195, no. 4 (2020): 71–77. http://dx.doi.org/10.32417/1997-4868-2020-195-4-71-77.

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Abstract. This article summarizes the results of a study of the cultural properties of the swine reproductive and respiratory syndrome virus isolate in transferable cultures of MA-104, PK-15, MARC-145 and Vero cells. The purpose of our research was to determine the sensitivity of cell culture lines to the swine reproductive and respiratory syndrome virus isolate, which is necessary for obtaining a highly active antigen as the main component of diagnostic and vaccine biologics. An isolate of the virus was isolated from a Piglet in the LPH of the Moscow region of the Kolomenskoye district. The i
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Zhang, Zhifei, Xueying Tang, Dagang Li, et al. "The Identification of RPL4 as a Hub Gene Associated with Goat Litter Size via Weighted Gene Co-Expression Network Analysis." Animals 14, no. 10 (2024): 1470. http://dx.doi.org/10.3390/ani14101470.

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Reproduction in goats is a highly complex and dynamic process of life regulation, involving coordinated regulation from various aspects such as central nervous system regulation, reproductive system development, oocyte maturation, and fertilized egg development. In recent years, researchers have identified numerous genes associated with goat reproductive performance through high-throughput sequencing, single-cell sequencing, gene knockout, and other techniques. However, there is still an urgent need to explore marker genes related to goat reproductive performance. In this study, a single-cell
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Wyffels, Jennifer T., Robert George, Lance Adams, et al. "Testosterone and semen seasonality for the sand tiger shark Carcharias taurus†." Biology of Reproduction 102, no. 4 (2019): 876–87. http://dx.doi.org/10.1093/biolre/ioz221.

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Abstract Understanding the fundamental reproductive biology of a species is the first step toward identifying parameters that are critical for reproduction and for the development of assisted reproductive techniques. Ejaculates were collected from aquarium (n = 24) and in situ (n = 34) sand tiger sharks Carcharias taurus. Volume, pH, osmolarity, sperm concentration, motility, status, morphology, and plasma membrane integrity were assessed for each ejaculate. Semen with the highest proportion of motile sperm was collected between April and June for both in situ and aquarium sand tiger sharks in
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Chong, L. D., and L. B. Ray. "Reproductive Biology." Science Signaling 2002, no. 138 (2002): eg9-eg9. http://dx.doi.org/10.1126/stke.2002.138.eg9.

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Santos, E. M., V. L. Workman, G. C. Paull, et al. "Molecular basis of sex and reproductive status in breeding zebrafish." Physiological Genomics 30, no. 2 (2007): 111–22. http://dx.doi.org/10.1152/physiolgenomics.00284.2006.

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The zebrafish ( Danio rerio) is used extensively as a model species for studies on vertebrate development and for assessing chemical effects on reproduction. Despite this, the molecular mechanisms controlling zebrafish reproduction are poorly understood. We analyzed the transcriptomic profiles of the gonads of individual zebrafish, using a 17k oligonucleotide microarray, to define the molecular basis of sex and reproductive status in sexually mature fish. The gonadal transcriptome differed substantially between sexes. Among the genes overexpressed in females, 11 biological processes were overr
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Comizzoli, Pierre, and William V. Holt. "Breakthroughs and new horizons in reproductive biology of rare and endangered animal species." Biology of Reproduction 101, no. 3 (2019): 514–25. http://dx.doi.org/10.1093/biolre/ioz031.

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Abstract Because of higher extinction rates due to human and natural factors, more basic and applied research in reproductive biology is required to preserve wild species and design proper strategies leading to sustainable populations. The objective of the review is to highlight recent, inspiring breakthroughs in wildlife reproduction science that will set directions for future research and lead to more successes in conservation biology. Despite new tools and approaches allowing a better and faster understanding of key mechanisms, we still know little about reproduction in endangered species.
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Huala, Eva, and Ian M. Sussex. "Determination and Cell Interactions in Reproductive Meristems." Plant Cell 5, no. 10 (1993): 1157. http://dx.doi.org/10.2307/3869769.

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Gosden, R., and N. Spears. "Programmed cell death in the reproductive system." British Medical Bulletin 53, no. 3 (1997): 644–61. http://dx.doi.org/10.1093/oxfordjournals.bmb.a011636.

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Ransick, Andrew. "Reproductive cell specification during Volvox obversus development." Developmental Biology 143, no. 1 (1991): 185–98. http://dx.doi.org/10.1016/0012-1606(91)90065-b.

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Kresovich, Jacob K., Christine G. Parks, Dale P. Sandler, and Jack A. Taylor. "Reproductive history and blood cell telomere length." Aging 10, no. 9 (2018): 2383–93. http://dx.doi.org/10.18632/aging.101558.

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Ionov, Ilya D. "The mast cell system in reproductive toxicology." Reproductive Toxicology 4, no. 4 (1990): 251–55. http://dx.doi.org/10.1016/0890-6238(90)90036-u.

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Schmidt, Christina M., Sandra Arbi, and Nigel C. Bennett. "Ovulation mitigates fatty liver associated with reproductive suppression and oxidative stress in Damaraland mole-rats (Fukomys damarensis)." Reproduction, Fertility and Development 32, no. 10 (2020): 923. http://dx.doi.org/10.1071/rd20049.

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Oxidative damage is often linked to reproduction; however, reproducing female Damaraland mole-rats (Fukomys damarensis) exhibit a reduction in oxidative damage relative to their non-reproductive, anovulatory, cohorts. Specifically, liver concentrations of malondialdehyde, a biomarker for lipid peroxidation, are significantly lower in reproducing females. We examined liver histology in reproductive, anovulatory and recently ovulating non-reproductive females, demonstrating an accumulation of lipid droplets only in the livers of anovulatory females and no fibrosis, cell death or inflammatory inf
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Robertson, Sarah. "Reproductive Immunology and Embryo Acceptance." Fertility & Reproduction 05, no. 04 (2023): 237. http://dx.doi.org/10.1142/s2661318223740511.

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Pregnancy is a test of the fundamental laws of transplantation immunology - the coexistence of genetically disparate tissues without host immune rejection. Advances over recent decades show that implantation and placental development depend on an active state of maternal immune tolerance, and breakdown of tolerance is a key contributor to infertility and recurrent pregnancy loss. Tolerance in pregnancy depends on regulatory T (Treg) cells, which are critical to inhibit effector immunity, constrain inflammation, and support maternal vascular adaptations that allow placental access to maternal n
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Bidne, K. L., M. J. Dickson, J. W. Ross, L. H. Baumgard, and A. F. Keating. "Disruption of female reproductive function by endotoxins." Reproduction 155, no. 4 (2018): R169—R181. http://dx.doi.org/10.1530/rep-17-0406.

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Endotoxemia can be caused by obesity, environmental chemical exposure, abiotic stressors and bacterial infection. Circumstances that deleteriously impact intestinal barrier integrity can induce endotoxemia, and controlled experiments have identified negative impacts of lipopolysaccharide (LPS; an endotoxin mimetic) on folliculogenesis, puberty onset, estrus behavior, ovulation, meiotic competence, luteal function and ovarian steroidogenesis. In addition, neonatal LPS exposures have transgenerational female reproductive impacts, raising concern about early life contacts to this endogenous repro
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Bagchi, D., N. S. Deshmukh, F. C. Lau, and M. Bagchi. "Reproductive." Experimental and Toxicologic Pathology 61, no. 4 (2009): 405. http://dx.doi.org/10.1016/j.etp.2009.02.093.

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Pan, Jing, and Jianwei Zhang. "Research Progress of PCNA in Reproductive System Diseases." Evidence-Based Complementary and Alternative Medicine 2021 (October 21, 2021): 1–8. http://dx.doi.org/10.1155/2021/2391917.

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Reproductive system diseases have become a public health problem that endangers human physical and mental health. The causes of reproductive diseases are complex and diverse. From a biological point of view, abnormal cell proliferation may affect important physiological functions of reproductive organs and cause various gynecological or andrological diseases. Proliferating cell nuclear antigen (PCNA) is the most commonly used indicator for detecting cell proliferation activity. The up- or downregulation of its expression is of great significance in reproductive system diseases. This review sum
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Gavrilov-Zimin, I. A. "Reproductive Criteria of Multicellularity and Original Modes of Reproduction." Успехи современной биологии 143, no. 6 (2023): 523–52. http://dx.doi.org/10.31857/s0042132423060042.

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The reproductive criteria of multicellularity are proposed for the first time. Terminologically the multicellularity is advised to subdivide into three variants: 1) protonemal – the most primitive, known in multicellular prokaryotes, in majority groups of multicellular algae and in gametophytes of some embryophyte plants; 2) siphonoseptal, distributed amongst multicellular fungi, some groups of green and yellow-green algae; 3) embryogenic, the most complicated, characteristic of all animals (Metazoa), sporophytes and some gametophytes of embryophyte plants, charophyte algae (Charophyceae s.s.)
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Xu, Zhongneng. "Sex and reproduction: a theoretical analysis." Biological Journal of the Linnean Society, January 27, 2024. http://dx.doi.org/10.1093/biolinnean/blad109.

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Abstract Sex in some organisms shows a continuous spectrum. Sometimes sexual differences in an individual’s organs are contradictory and determined by physiological, pathological and environmental factors, leading to debate over the definitions of sex in individuals. This study indicates that the essence of sex during reproduction distinguishes between reproductive subjects and that the unit of reproduction is not the individual but the reproductive cell. To properly supplement the existing definitions of sex, a definition of sex in reproduction in which only reproductive cells have sexes was
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Hashemi Karoii, Danial, and Hossein Azizi. "Functions and mechanism of noncoding RNA in regulation and differentiation of male mammalian reproduction." Cell Biochemistry and Function, August 16, 2023. http://dx.doi.org/10.1002/cbf.3838.

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AbstractNoncoding RNAs (ncRNAs) are active regulators of a wide range of biological and physiological processes, including the majority of mammalian reproductive events. Knowledge of the biological activities of ncRNAs in the context of mammalian reproduction will allow for a more comprehensive and comparative understanding of male sterility and fertility. In this review, we describe recent advances in ncRNA‐mediated control of mammalian reproduction and emphasize the importance of ncRNAs in several aspects of mammalian reproduction, such as germ cell biogenesis and reproductive organ activity
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