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Bibliographies thématiques / Reticulo cytopenia

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Littérature scientifique sur le sujet « Reticulo cytopenia »

Auteur : Grafiati

Publié le 2 juin 2025

Mis à jour le 31 juillet 2025

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Articles de revues sur le sujet "Reticulo cytopenia"

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Deldar, A., H. Lewis, J. Bloom, and L. Weiss. "Cephalosporin-induced Changes in the Ultrastructure of Canine Bone Marrow." Veterinary Pathology 25, no. 3 (1988): 211–18. http://dx.doi.org/10.1177/030098588802500305.

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Fourteen healthy dogs were given 540 to 840 mg/kg of cefazedone (Refosporen®) intravenously for up to 4 months or until peripheral blood cell counts were depressed. Within 6 to 10 weeks treated dogs developed pancytopenia (5/14), thrombocytopenia (11/14), moderate to severe neutropenia (8/14), and/or normocytic anemia with erythroblastemia (8/14). Ultrastructural changes in bone marrow of severely cytopenic dogs included mitochondrial damage in hematopoietic and nonhematopoietic cells, thickening of endosteal bone lining layers, increased adventitial coverage of vascular sinuses, and an increa

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Alana Vicente, Bhavisha A. Patel, Fernanda Gutierrez-Rodrigues, et al. "Eltrombopag monotherapy can improve hematopoiesis in patients with low to intermediate risk-1 myelodysplastic syndrome." Haematologica 105, no. 12 (2020): 2785–94. http://dx.doi.org/10.3324/haematol.2020.249995.

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Myelodysplastic syndromes (MDS) are a group of clonal myeloid disorders characterized by cytopenia and a propensity to develop acute myeloid leukemia (AML). The management of lower-risk (LR) MDS with persistent cytopenias remains suboptimal. Eltrombopag (EPAG), a thrombopoietin receptor agonist, can improve platelet counts in LR-MDS and tri-lineage hematopoiesis in aplastic anemia (AA). We conducted a phase 2 dose modification study to investigate the safety and efficacy of EPAG in LR-MDS. EPAG dose was escalated from 50 mg/day, to a maximum of 150 mg/day over a period of 16 weeks. The primary

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Srinivas, G., D.V. Ramanjaneyulu, E. Muralinath, et al. "An Essential Parameters of Parvo Virus Include Patho Physiology, Histo Pathology, Diagnosis, Differential Diagnosis, Treatment and Prognosis." Journal of Research and Reviews in Nursing Science and Education 2, no. 2 (2025): 11–17. https://doi.org/10.5281/zenodo.15541791.

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<em>One virus that only affects people is parvovirus B19. The fifth illness, also known as erythema infectious or slapped cheek syndrome, is known to be caused by it. It primarily affects young children, though it can sometimes affect adults. In addition, it may result in Poly arthropathy, popular-purpuric gloves and socks syndrome (PPGSS) in young people, certain anemias, hydrops fetalis, particularly in pregnant women, and an aplastic crisis. Viral transmission occurs through both respiratory secretions and blood products. The virus can infect a pregnant woman and then infect her unborn chil

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Mathew, Josy, Surbhi Shah, and Virginia L. Kubic. "Bone Marrow Biopsy Findings in Patients with Hepatitis C Infection." Blood 120, no. 21 (2012): 4840. http://dx.doi.org/10.1182/blood.v120.21.4840.4840.

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Abstract Abstract 4840 Patients with hepatitis C often present with cytopenias - thrombocytopenia, neutropenia and less commonly anemia. Hypersplenism may contribute to cytopenias but effects on the bone marrow due to the hepatitis C infection also likely play a role in its pathogenesis. Hepatitis C infection predisposes to development of lymphomas as well. The bone marrow findings in patients with hepatitis C infection are not well described and to our knowledge there has only been one peer reviewed study published till date. In order to elucidate this further, we conducted a retrospective re

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Mailloux, Adam, Ling Zhang, Lynn Moscinski, et al. "Pathophysiology of cytopenias in an autoimmune lymphoproliferative disease linked to bone marrow fibrosis (P3165)." Journal of Immunology 190, no. 1_Supplement (2013): 43.44. http://dx.doi.org/10.4049/jimmunol.190.supp.43.44.

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Abstract Large Granular Lymphocyte (LGL) leukemia is associated with unexplained cytopenias, autoimmune features, and CD57+CD8+perforin+ T-cell lympoproliferation. Like many autoimmune disorders, the pathophysiology of cytopenias in LGL leukemia is unknown. Bone marrow (BM) pathology from 24 LGL leukemia patients was retrospectively studied using H&E, reticulin, and trichrome-stained sections, and revealed that BM fibrosis was present in 21 out of 24 patients (88%). Fibrosis, a previously undefined complication, was significantly associated with splenomegaly, the presence of cytopenias, an

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Logue, Jennifer Marilyn, Gabriel S. Krivenko, Victoria Larson, et al. "Cytopenia following axicabtagene ciloleucel (axi-cel) for refractory large B-cell lymphoma (LBCL)." Journal of Clinical Oncology 37, no. 15_suppl (2019): e14019-e14019. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e14019.

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e14019 Background: Axi-cel is an anti-CD19 CAR T-cell therapy that can lead to long term disease control for patients with refractory LBCL including DLBCL, PMBCL, HGBL, and tFL. Beyond day 30, grade 3 or higher cytopenias were reported in 17% of patients (Locke 2019). We sought to further characterize cytopenias after axi-cel. Methods: We evaluated patients with LBCL treated with axi-cel at Moffitt from May 2015 to May 2018. Counts at apheresis and days 30, 90 and 180 after axi-cel infusion were recorded. Data was censored at date of progression, death or last follow-up. AEs were per CTCAE v4.

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Fattizzo, Bruno, Silvia Cantoni, Rachele Zavaglia, et al. "Efficacy and Safety of Cyclosporine Treatment in Autoimmune Cytopenias: The Experience of Two Italian Reference Centers." Blood 138, Supplement 1 (2021): 3146. http://dx.doi.org/10.1182/blood-2021-149043.

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Abstract Background: Autoimmune cytopenias (immune thrombocytopenia ITP, autoimmune hemolytic anemia AIHA, and chronic idiopathic neutropenia CIN) are a heterogeneous group of disorders characterized by the presence of autoantibodies directed against platelets (PLT), erythrocytes, and neutrophils (ANC). Frontline steroids are the mainstay of treatment, although most patients relapse and require 2 nd line therapies which slightly differ according to disease subtype. Rituximab is mainly effective in AIHA, although only a fraction of cases would experience long-term relapse-free. Splenectomy may

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Juvvadi, R., J. M. Rossetti, R. K. Shadduck, et al. "Response to azacitidine in patients with myelodysplastic syndrome with marrow fibrosis." Journal of Clinical Oncology 25, no. 18_suppl (2007): 7089. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.7089.

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7089 Background: The Myelodysplastic syndrome (MDS) is characterized by aberrant hematopoietic progenitor cell maturation resulting in ineffective hematopoiesis, cytopenia and progression to acute myeloid leukemia. Some individuals with MDS also have fibrosis within the marrow. MDS with marrow fibrosis appears to be biologically and clinically distinct from myeloproliferative disorders with marrow fibrosis such as agnogenic myeloid metaplasia. While azacitidine (AZA), a DNA methyl transferase inhibitor has known activity in MDS, little is known about its efficacy in patients with MDS with marr

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Khera, Sanjeev, Priyanka Misra, Kanwaljeet Singh, and Preeti Tripathi. "Complete resolution of primary myelofibrosis in an infant with steroids and hydroxyurea." BMJ Case Reports 16, no. 11 (2023): e256210. http://dx.doi.org/10.1136/bcr-2023-256210.

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Paediatric primary myelofibrosis (PMF) is exceedingly rare and distinct compared with adult PMF. It is characterised by peripheral blood cytopenias, leucoerythroblastosis, reticulin fibrosis, extramedullary haematopoiesis and hepatosplenomegaly. In the absence of laid down diagnostic criteria, the diagnosis is largely of exclusion. Though early haematological stem cell transplant (HSCT) remains the treatment of choice, spontaneous remission or remission with steroids and/or cytoreductive agents is described in around 20% of cases of paediatric PMF. Moreover, HSCT in paediatric PMF is associate

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Jafarzadeh, Bita, Vahid Mehrtash, Hortense Le, et al. "A Self-Supervised Machine Learning Model Can Differentiate MDS from Clinical Mimics Based on Bone Marrow Biopsy Features." Blood 144, Supplement 1 (2024): 7496. https://doi.org/10.1182/blood-2024-211667.

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Introduction: The pathologic evaluation of bone marrow biopsies (BMBx) for diagnosing myelodysplastic syndrome (MDS) is challenging due to the limited cytologic detail provided by H&E sections. Diagnosing MDS requires a sophisticated, integrative approach because of its complex clinical and histopathological presentations. In this study, we investigate whether integrating features from both H&E and reticulin-stained BMBx slides using self-supervised learning (SSL) image analysis could address these limitations by developing an algorithm capable of reliably distinguishing MDS from its c

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