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Articles de revues sur le sujet « Salivary Gland Tumour »

Auteur : Grafiati

Publié le 7 juin 2025

Mis à jour le 2 août 2025

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1

Brodetskyi, I. S., V. A. Malanchuk, and V. E. Dosenko. "USE OF 29A MICRO-RNA FOR DIAGNOSIS OF PLEOMORPHIC ADENOMAS OF SALIVARY GLANDS." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 20, no. 1 (2020): 149–54. http://dx.doi.org/10.31718/2077-1096.20.1.149.

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Introduction. Pleomorphic adenoma is known as the most common tumour in salivary glands that makes up 60-90% of all benign tumours of the salivary glands. The modern genetic tendency towards the diagnosis of salivary gland tumours is the study of the role of microRNA molecules, and miRNA-29a in the focus of the great researchers’ interest. It is expressed in 84 % of the pleomorphic adenomas of the salivary glands. Objectives. Determination of expression of miRNA-29a in tissues of pleomorphic adenomas of the large salivary glands that adjacent to the tumour of the tissue of the salivary gland,

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Bourgeois, Jacqueline M., Jasim Radhi, Lisa Elden, and Gerald Gill. "Plexiform Neurofibroma of the Submandibular Salivary Gland in a Child." Canadian Journal of Gastroenterology 15, no. 12 (2001): 835–37. http://dx.doi.org/10.1155/2001/675485.

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Plexiform neurofibromas in major salivary glands are rarely described. In the literature, most reported tumours have been present in the parotid gland region. A three-year-old boy with a family history of neurofibromatosis presented with a rapidly growing left submandibular mass. The clinical diagnosis was that of a neurofibroma rather than a primary salivery gland tumour. Resection of the lesion revealed a plexiform neurofibroma involving the submandibular gland. Although these tumours have a neurogenic rather than a salivary gland origin, they must be considered in the differential diagnosis

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Goyal, Anjali, Deep Pravinbhai Chauhan, Kunjan Pramodbhai Patel, and Darshan Rajeshbhai Parmar. "Acinic cell carcinoma of left parotid gland: A case report." IP Archives of Cytology and Histopathology Research 9, no. 3 (2024): 163–66. http://dx.doi.org/10.18231/j.achr.2024.036.

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Acinic cell carcinoma (ACC) is an uncommon and gradually developing tumour primarily found in the major salivary glands, most frequently originating in the parotid gland and less commonly in the submandibular and sublingual glands. ACC represents 3 to 4% of parotid gland tumours, 2 to 6% of all salivary gland tumours, and 10 to 17% of all malignant tumours in the salivary glands.

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-, Arifullah, Irfan Ul Islam Nasir, Syed Zafar Hassan, and Ghulam Muhammad. "SALIVARY GLAND TUMOURS;." Professional Medical Journal 24, no. 09 (2017): 1327–30. http://dx.doi.org/10.29309/tpmj/2017.24.09.809.

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Objectives: The objective of the study was to find the frequency of salivarygland tumours. Study Design: A descriptive study. Period: 1st Jan 2008 to 31st Dec 2010 (of 3years duration). Setting: ENT department Khyber Teaching Hospital and Surgical departmentHayatabad Medical Complex, Peshawar. Material and methods: Total number of 108 patientshaving salivary gland tumours enrolled from admitted patients in ENT department KhyberTeaching Hospital and Surgical department Hayatabad Medical Complex Peshawar. Thestudy was designed to find the frequency of salivary gland tumours. Results: In our stud

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E., Rajesh Goud, Manideep B., Malyadri Paladugu, and Somnath Gupta. "A rare case of minor salivary gland tumor presenting as parapharyngeal tumor." International Journal of Otorhinolaryngology and Head and Neck Surgery 11, no. 3 (2025): 316–19. https://doi.org/10.18203/issn.2454-5929.ijohns20251522.

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Parapharyngeal space tumours (PPS) are benign, uncommon located in the head and neck region. Pleomorphic adenoma the most prevalent type of salivary gland tumour can develop from the salivary glands or start in the deep lobe of the parotid gland and spread into PPS. A 59-year-old male presented with complaints of dysphagia, voice change and swelling in the soft palate. PPS tumour was detected with endoscopy, biopsy confirmed it as salivary gland tumour and PET-CT scan findings revealed a large hyper metabolic solid soft tissue density lesion in left parapharyngeal space with local extent. Tumo

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Lau, D. P. C., M. J. Goddard, I. D. Bottrill, and D. A. Moffat. "Epithelial-myoepithelial carcinoma of the parotid gland. An unusual cause of ear canal stenosis." Journal of Laryngology & Otology 110, no. 5 (1996): 493–95. http://dx.doi.org/10.1017/s0022215100134085.

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AbstractEpithelial-myoepithelial carcinoma (EMC) accounts for approximately one per cent of salivary gland tumours. This tumour is gaining wider recognition following inclusion into the WHO histological classification of salivary gland tumours in 1990. Salivary gland tumours characteristically present with an enlarging mass. We describe an unusual presentation of a salivary gland tumour with stenosis of the external ear canal in the absence of a palpable mass. EMC usually arises from the salivary glands but isolated cases have been described arising primarily from the paranasal sinuses, trache

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Darling, Mark R., Nelly N. Hashem, Irene Zhang, et al. "Kallikrein-related peptidase 10 expression in salivary gland tissues and tumours." International Journal of Biological Markers 27, no. 4 (2012): 381–88. http://dx.doi.org/10.5301/jbm.2012.10373.

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Objectives Kallikrein-related peptidase 10 (KLK10) has been implicated in the development of several types of cancer. The purpose of this study was to analyze the expression of KLK10 in 3 types of salivary gland tumour and normal salivary glands. Materials and methods: A standard immunoperoxidase staining technique was used to assess the Immunoexpression profile of KLK10 in normal salivary glands and 3 types of salivary gland tumour: pleomorphic adenoma, adenoid cystic carcinoma and mucoepidermoid carcinoma. Results Pleomorphic adenomas showed significantly lower KLK10 levels than control tiss

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Mahamad Apandi, Nurul, Siew Chan, and Yen Toh. "Differential Expression of Mucin in Salivary Gland Tumours." Medicina 60, no. 6 (2024): 920. http://dx.doi.org/10.3390/medicina60060920.

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Background and Objectives: Mucin has been implicated via various mechanisms in the development and growth of tumour cells. However, mucin expression studies in salivary gland tumours are limited, especially with samples from minor salivary glands. This study aims to investigate and compare mucin expression in benign and malignant salivary gland tumours of minor and major salivary gland origins. Materials and Methods: Special stains were used to stain neutral mucin (Periodic acid Schiff), sialomucin (Alcian Blue) and sulfomucin (Aldehyde Fuschin) within tissues from six normal salivary glands a

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Mustafa, Wan Mahadzir, Nornazaliza Basri, and Abdul Rahim Zakaria. "Salivary gland tumours in Hospital Kuala Lumpur." Malaysian Journal of Oral and Maxillofacial Surgery 8, no. 1 (2010): 6–11. https://doi.org/10.4103/mjoms_201081_6.

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OBJECTIVE: The purpose of this study was to document the pattern of salivary gland tumours that were treated in Department of Oral and Maxillofacial Surgery, Hospital Kuala Lumpur, during the 10-year period. MATERIAL AND METHOD: Data of 18 patients were retrieved from the operation theatre book and clinical records from the year 2000-2009. The collection of data included presenting symptoms, gender, age, ethnicity, location, histopathology and treatment of the tumour. RESULTS: The most common presenting symptom was swelling. The patients' ages ranged from 16 to 62 years and the peak incidence

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Radin Siti Hajar Radin Abdul Halim, Mohd Aznan Md Aris, and Azliana Abd Fuaat. "Warthin Tumour: A Case Report and Approach in Primary Care." Asian Journal of Medicine & Health Sciences 7, no. 2 (2024): 301–7. https://doi.org/10.70672/ky9bz347.

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Warthin tumour (WT) is an infrequent benign salivary gland neoplasm, that primarily occur in the parotid gland, the largest of the salivary glands. Comprising roughly 15% of all salivary gland tumours, these lesions are the second most prevalent type of salivary gland neoplasm after pleomorphic adenoma encountered in clinical practice. Here, we report a case of Warthin tumour of six years’ duration in a 46-year-old male patient in the left parotid gland and will discuss the diagnostic process, differential diagnoses, and management of a suspected WT in a primary care setting. While Warthin tum

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Dr., Ankit Goyal, Naveen Shukla Dr., and Priyali Chauhan Dr. "Pleomorphic Adenoma of Upper Lip - A Case Report." International Journal of Research and Review 6, no. 2 (2019): 16–19. https://doi.org/10.5281/zenodo.3987033.

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Pleomorphic adenoma is a benign neoplasm which represents two thirds of all tumours of the major salivary glands and less than half of those in the minor salivary glands, with the greatest frequency of occurrence in the superficial lobe of the parotid gland. Most common intraoral site of minor salivary gland tumour is palate. Pleomorphic adenoma of the lips is rare.

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Abbeerami, S., Sujatha G.P. Dr., and Shambulingappa P. Dr. "An Unusual Case Report of Pleomorphic Adenoma of Minor Salivary Glands of Palate." INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND BIO-MEDICAL SCIENCE 04, no. 09 (2024): 736–38. https://doi.org/10.5281/zenodo.13759024.

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Pleomorphic adenoma is a benign salivary gland tumour that exhibits wide cytomorphologic and architectural diversity. Pleomorphic adenoma (or benign mixed tumour) is a common benign salivary gland neoplasm characterised by neoplastic proliferation of epithelial (ductal) cells along with myoepithelial components, having a malignant potentiality. This paper presents a case of pleomorphic adenoma arising from minor salivary glands of palate in a female patient along with review of literature.

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Rajan, Shiv, Ajay Kumar Singh, Sumaira Qayoom, Palavalasa Niranjan, and Deep Chakrabarti. "Polymorphous adenocarcinoma of the submandibular gland." BMJ Case Reports 14, no. 8 (2021): e244218. http://dx.doi.org/10.1136/bcr-2021-244218.

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Polymorphous adenocarcinoma (PA) of the salivary glands is a rare malignancy that predominantly affects the minor salivary glands of the palate. Major salivary gland involvement is rare (<5%). The submandibular gland is a highly unusual location for this tumour. Recently, the WHO has updated the classification of salivary gland tumours in which the PA subtype has been modified. We report a very uncommon case of a classical variant of PA involving the submandibular gland in a 49-year-old woman managed at our institute and discuss the most recent pathological criteria for diagnosis, managemen

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Islam, Rashedul, Mostafa Kamal Arefin, Md Nazmul Islam, Md Abu Yusuf Fakir, and Shaikh Nurul Fattah Rumi. "Clinicopathological Study of Salivary Gland Tumours." Bangladesh Journal of Otorhinolaryngology 28, no. 1 (2022): 96–102. http://dx.doi.org/10.3329/bjo.v28i1.60833.

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Background: Salivary gland tumours are relatively uncommon and constitute 3% to 10% of all head & neck neoplasms. The majority of salivary gland tumours arise in the parotid gland. Objectives: To search the clinicopathological presentation of salivary gland tumours. Methods: This was a cross sectional study. Results: The highest incidence of benign tumors was in the 3rd and 4th decade, whereas for malignant tumor it was the 5thdecade of life. Among 47 male patients, 72.3% had benign and 27.7% cases had malignant tumours. Out of 40 female patients 45% cases had benign and

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Madiyal, Ananya, Babu G. Subhas, Vidya Ajila, and Shruthi Hegde. "Basal cell adenocarcinoma of the tongue- A rarity Case report." ARS Medica Tomitana 23, no. 4 (2017): 184–88. http://dx.doi.org/10.1515/arsm-2017-0034.

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Abstract Basal cell adenocarcinoma is an unusual basaloid tumour that usually affects the parotid and very rarely involves the submandibular or minor salivary glands. It constitutes 1.6% of all salivary gland tumours and occurs as an asymptomatic freely mobile mass with occasional lymph node metastasis. Differentiation from benign salivary gland tumours like basal cell adenoma is accomplished by determining the depth of tumour invasion and patterns of growth or infiltration. Although it is categorised as a low-grade malignancy, it has a high propensity for recurrence. Surgical excision with a

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Muddaiah, Dechu, Srinivas Venkatarangaiah, Prashanth V, and Mohammed Adil Hussain M. "Schwannoma of the Submandibular Gland." Bengal Journal of Otolaryngology and Head Neck Surgery 28, no. 1 (2020): 80–83. http://dx.doi.org/10.47210/bjohns.2020.v28i1.178.

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Introduction Mesenchymal tumours of submandibular gland are extremely rare. Schwannoma of the salivary glands is a particularly rare form of an extracranial neurogenic tumour. Case Report Here, we present an unusual case of schwannoma of submandibular gland in a 16 year old girl, who underwent total excision of mass with submandibular gland excision with no cranial nerve deficits. The details of the histopathologic features are present .  Discussion Schwannoma of the salivary gland is a particularly rare form of an extracranial neurogenic tumour. Our case in

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Bains, Amandeep, Thomas Dennis, and Dimtrios Doumpiotis. "A Palatal Myoepithelioma." Dental Update 46, no. 7 (2019): 684–85. http://dx.doi.org/10.12968/denu.2019.46.7.684.

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This case report demonstrates the management of a myoepithelioma in the minor salivary glands of the palate. Myoepitheliomas are rare, benign, salivary gland tumours which usually affect the parotid glands. The rare neoplasms only account for 1–1.5% of all salivary gland neoplasms. This case shows a minimal approach to treating this rare tumour found in a rare site. CPD/Clinical Relevance: This case demonstrates the potential for rapid epithelial recovery within the oral cavity.

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Mili, M. K., Hirak Jyoti Das, Asha Saikia, N. J. Saikia, J. Phookan, and Mridusmita Gohain. "Salivary gland tumours: a hospital-based study on demographic and incidence pattern, histopathological types and treatment strategy." International Journal of Otorhinolaryngology and Head and Neck Surgery 6, no. 12 (2020): 2218. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20205062.

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<p><strong>Background: </strong>Salivary gland tumours constitute 3-4% of all head and neck cancers (mostly benign). These tumours are epithelial (95%) or mesenchymal in origin. Pleomorphic adenoma is the most common benign salivary gland tumour and mucoepidermoid carcinoma (45%) is the most common malignant salivary gland tumour followed by adenoid cystic carcinoma (30%). The parotid, submandibular and the minor salivary glands of palate are commonly involved and the sublingual gland is rarely affected.</p><p><strong>Methods: </strong>Hospital based c

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M, Kamath, Nuzhrat T, and Shetty S. "Histopathological study of salivary gland lesions in a tertiary care center." Journal of Medical and Scientific Research 13, no. 2 (2025): 173–76. https://doi.org/10.17727/jmsr.2024/13-30.

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Introduction: Salivary gland neoplasms constitute about 3% of all head and neck neoplasms and are relatively uncommon. Majority of the tumours are seen in the parotid gland followed by submandibular and other minor salivary glands. Histopathology is the gold standard in diagnosis of salivary gland lesions. The aim of this study was to study the frequency, site and the histopathological spectrum of salivary gland lesions in our institute. Materials & methods: This was a retrospective study done in the Department of Pathology, Kanachur Institute of Medical Sciences. Resected salivary gland s

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Gajbhiye, Ashok S., Mukteshwar N. Deshmukh, Parag K. Jaipuriya, et al. "Pleomorphic adenoma of submandibular gland: not so common occurrence." International Surgery Journal 5, no. 2 (2018): 657. http://dx.doi.org/10.18203/2349-2902.isj20180371.

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Background: The salivary glands tumour are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes. Several studies have been conducted on the tumors of the parotid and minor salivary glands, but very few reports in the literature have focused on submandibular gland tumors as they are rare and are usually grouped with other salivary glands. Approximately 70% of the salivary gland tumors affect parotid gland with the submandibular gland being affected in 5-10% of the cases, sublingual gland in 1% and minor glands in 5-15% of the cases. So, we describe

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Deere, H., I. Hore, N. McDermott, and T. Levine. "Epithelial-myoepithelial carcinoma of the parotid gland: a case report and review of the cytological and histological features." Journal of Laryngology & Otology 115, no. 5 (2001): 434–36. http://dx.doi.org/10.1258/0022215011907875.

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Epithelial-myoepithelial carcinoma (EMC) is a rare biphasic tumour of the salivary glands typically arising in the parotid. Fine needle aspiration cytology is widely used in the initial investigation of salivary gland swellings and whilst the cytological features of this tumour have been described they are not well recognized. This report describes the clinicopathological features of a case of epithelial-myoepithelial carcinoma of the parotid gland and highlights the importance of awareness of this tumour in the differential diagnosis of biphasic tumours on fine needle aspiration cytology.

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Kronenberg, Jona, Ada Horowitz, and Doras Creter. "Pleomorphic adenoma arising in accessory salivary tissue with constriction of Stensen's duct." Journal of Laryngology & Otology 102, no. 4 (1988): 382–83. http://dx.doi.org/10.1017/s0022215100105055.

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AbstractAccessory salivary gland tissue is well recognized and is found in 21 per cent of the population. Tumours of the accessory salivary tissue are rare and comprise only 1 per cent of all parotid gland tumours.A pleomorphic adenoma of Stensen's duct is described. A circular constriction of this duct by the tumour with retention of saliva in the parotid gland was observed.

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George, M. K., Paul Mansour, and A. L. Pahor. "Terminal parotid duct carcinoma." Journal of Laryngology & Otology 105, no. 9 (1991): 780–81. http://dx.doi.org/10.1017/s0022215100117311.

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AbstractTerminal duct carcinoma of salivary glands is an uncommon, histologically distinctive, low grade malignant neoplasm arising from the intercalated salivary duct. We present a case arising eight years after removal of a parotid tumour reported as a pleomorphic adenoma. We describe the clinico-pathological features of the present tumour, illustrate the difficulties that may be encountered in differentiating it from other salivary gland tumours, and discuss the possible significance of the previous tumour.

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Kumari, Rashmi, Vivekanand, and Sarfaraz Alam Md. "Study of Outcomes and Surgical Approach in Swelling of Salivary Gland." International Journal of Pharmaceutical and Clinical Research 15, no. 8 (2023): 749–52. https://doi.org/10.5281/zenodo.11493780.

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<strong>Background:</strong> Salivary gland tumours are rare tumours and majority of these are benign and about 20% are malignant. The incidence of salivary gland cancers ranges from 0.5 to 2 per 100,000 in different parts of the world. Salivary gland swellings in the parotid or submandibular glands usually present as an enlarging mass and may be associated with neurological symptoms like facial nerve paralysis or pain. Minor salivary gland tumours present as a submucosal intraoral mass which subsequently ulcerates. Acute inflammatory conditions generally can be diagnosed by history and p

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Sheereen, Shazima, Mohnish Zulfikar Manva, Shamama Sheereen, Namrata N. Patil, Rawa K. Abdelrahim, and Mohammed Malik Afroz. "“Pleomorphic adenoma in salivary glands: Insights from a 100-patient analysis”." Journal of Oral and Maxillofacial Pathology 28, no. 1 (2024): 42–48. http://dx.doi.org/10.4103/jomfp.jomfp_452_23.

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Introduction: Pleomorphic adenoma (PA) is a benign epithelial tumour originating from the salivary gland, specifically the parotid gland. This study aims to comprehensively analyse the clinical and pathological features of PA by examining the characteristics of the tumour, including its histological structure and immunohistochemical profile. Materials and Methods: Over 8 years, beginning in October 2015 and ending in October 2023, an exhaustive retrospective study was conducted in the Department of Pathology, Kasturba Medical College, Mangalore, Manipal University, Karnataka, India. The resear

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Baharudin, A., A. Khairuddin, A. Nizam, and A. R. Samsuddin. "Evaluation of irradiated salivary gland function in patients with head and neck tumours treated with radiotherapy." Journal of Laryngology & Otology 123, no. 1 (2008): 108–13. http://dx.doi.org/10.1017/s0022215108002466.

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AbstractIntroduction:Radiotherapy is an important treatment modality for head and neck tumours. One of its major drawbacks is post-treatment salivary gland hypofunction. This study was performed to objectively evaluate the salivary gland function in post-irradiated head and neck tumour patients.Methods:We performed a cross-sectional study of 30 patients with head and neck tumours who had received radiotherapy. Unstimulated and stimulated whole salivary flow rates were assessed in these 30 patients, and compared with those of 30 normal subjects. Unstimulated whole saliva was measured by the dra

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Babu N., Sathish, Naveen H. Mahadev, and Kumar G. V. "A clinical study of the incidence of salivary gland tumors in a tertiary care teaching hospital." International Surgery Journal 6, no. 6 (2019): 2110. http://dx.doi.org/10.18203/2349-2902.isj20192376.

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Background: The salivary gland system of the upper aero digestive tract plays a critical role in the functions of digestion, respiration, communication, and overall homeostasis. The Salivary gland swellings can be broadly classified into inflammatory, non-inflammatory and neoplastic swellings like calculi, benign tumours such has pleomorphic adenoma, oncocytoma, Warthin's tumour, malignant tumors which include-adenocarcinoma, adenoid cystic carcinoma, undifferentiated carcinoma.Methods: The present cross-sectional study was conducted at the Department of general surgery, Sri Siddhartha Medical

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Toynton, S. C., M. J. Wilkins, H. T. Cook, and N. D. S. Stafford. "True mailgnant mixed tumour of a minor salivary gland." Journal of Laryngology & Otology 108, no. 1 (1994): 76–79. http://dx.doi.org/10.1017/s0022215100125927.

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True malignant mixed tumours (carcinosarcomas) of salivary gland origin are rare and not widely recognized lesions. These tumours account for approximately 0.2 per cent of all malignancies of the major salivary glands (Stephen et al., 1986). They usually occur in pre-existing pleomorphic ademonas of major salivary glands and have an aggressive and often rapidly fatal progression.We report a case of carcinosarcoma in a minor salivary gland of the upper lip. Its management and the use of immunocy-tochemical stains to demonstrate the separate epithelial and connective issue components are discuss

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Pachori, Geeta, Subhash Chandra, Naseem A. Bihari, and Neena Kasliwal. "Histopathological spectrum of salivary gland lesions in Ajmer region, Rajasthan, India." International Journal of Research in Medical Sciences 7, no. 7 (2019): 2708. http://dx.doi.org/10.18203/2320-6012.ijrms20192904.

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Background: There is a wide spectrum of salivary gland lesions with morphological and clinical diversity which makes it a difficult task for histopathological interpretation. Tumours of salivary glands are uncommon accounting for 3-10% of the total tumors of head and neck region and less than one percent of all tumours. The aim of this study was to recognize various histomorphological patterns of salivary gland lesions, their frequency, age, gender and site wise distribution.Methods: This study was carried out from June 2015 to May 2018 in the department of Pathology, JLN Medical College and a

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Mirza, Showkat, Sunil N. Dutt, Richard M. Irving, and E. L. Jones. "Intraductal papilloma of the submandibular gland." Journal of Laryngology & Otology 114, no. 6 (2000): 481–83. http://dx.doi.org/10.1258/0022215001905931.

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Salivary tissue intraductal papillomas are rare, benign tumours that predominantly affect minor salivary glands. We report a case of an intraductal papilloma arising in the unusual site of the submandibular gland. The tumour was completely excised and recurrence is not expected. A brief review of this histologically distinct lesion is presented.

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Dr., Sanchita Kalita, and Smrity Rupa Borah Dutta Dr. "An Unusual Presentation of Basal Cell Adenoma of Ectopic Salivary Gland Tissue: A Case Report." International Journal of Science and Healthcare Research 3, no. 2 (2018): 122–25. https://doi.org/10.5281/zenodo.3936573.

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Salivary gland tumors constitute about 2% to 6.5% of all head and neck region tumors. Basal cell adenoma (BCA) of the salivary glands is an uncommon benign epithelial tumour. It is considered as a low-grade malignant tumour with a high recurrence rate and, in general, good prognosis. BCA represents 54% of monomorphous adenomas and 1-3% of major salivary glands tumours. Most of these tumors are located on the parotid region (80%). In this case report, we are highlighting an unusual location of this not so commonly encountered tumour and its related diagnostic confusion.  

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Dr., Suresh Bommaji, G. Kailasakumar Reddy Dr., Vaishnavi Potluri Dr., Sowmya Mantha Dr., and Sandhya Rampati Dr. "The Bizarre Case of Warthins Tumor in Submandibular Gland-Case Report." International Journal of Innovative Science and Research Technology 8, no. 4 (2023): 1170–78. https://doi.org/10.5281/zenodo.7889043.

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The second most frequent salivary gland tumour after pleomorphic adenoma, Warthin's tumour is also known as adenolymphoma, cystadenolymphoma, and papillary cystadenoma lymphomatosum. It often develops from the parotid gland and makes up between 4% and 13% of all salivary gland tumours. With relative rates of 6.9% and8%, extraparotid Warthin tumours from the submandibular gland and cervical lymph nodes are extremely uncommon. Moreover, Warthins tumours that originate in the minor salivary gland are incredibly uncommon, with documented incidences ranging from 0.1% to 1.2%. Several cysts with

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Dewi, I. Gusti Ayu Sri Mahendra, I. Wayan Sudarsa, Ni Made Mahastuti, Putu Patriawan, Putu Erika Paskarani, and Budi Heryanto. "Parotid Gland Oncocytoma and Its Clinicopathological Approach: A Case Report." Indonesian Journal of Cancer 19, no. 1 (2025): 132–35. https://doi.org/10.33371/ijoc.v19i1.1233.

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Introduction: Oncocytoma is a benign tumor of the salivary glands consisting of oncocyte cells, occurring in approximately 2% of all salivary gland neoplasms, most of which occur in the parotid gland. This tumour most commonly occurs in the sixth to eighth decades of life, with a mean age of 64 years and without gender predilection. The clinical presentation is often misdiagnosed as pleomorphic adenoma, cystic lesion, and inflammation.Case Presentation: A 63-year-old male, complained of a lump under the right ear, for 7 years ago. It feels painless and slightly enlarged since a month before su

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Ukwas, Abdouldaim, Mahmoud Elshikh, Tijjani Umar, and Farzad Borumandi. "Leiomyoma of submandibular gland." BMJ Case Reports 17, no. 7 (2024): e258871. http://dx.doi.org/10.1136/bcr-2023-258871.

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Leiomyoma is a benign tumour of smooth muscle origin. Leiomyoma arising in major salivary gland is under-reported. We report a case of a woman in her 40s with a submandibular gland tumour which represented a diagnostic challenge during preoperative assessment. The core needle biopsy of submandibular gland tumour revealed a spindle cell tumour suggestive of an undifferentiated tumour. As a malignancy could not be excluded, the submandibular gland tumour was removed en bloc with surrounding lymph nodes in level Ib of the neck. Leiomyoma may be included in the differential diagnosis of spindle ce

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Swarnkar, Neha, Srinivasan Venkataraman, and Prasanna Kumar Saravanam. "Salivary gland tumours: a retrospective study at a tertiary care centre in South India." International Journal of Otorhinolaryngology and Head and Neck Surgery 7, no. 5 (2021): 825. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20211576.

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<p><strong>Background:</strong> Salivary gland tumors are morphologically and histologically diverse group of lesions and their frequency varies in several parts of the world. Better understanding of these tumours will help in assessing the behaviour and outcomes of lesions of this region. The aim of this study was to analyse the charactertistics of different tumours occurring in the salivary gland in a tertiary care centre in South India.</p><p class="abstract"><strong>Methods:</strong> A retrospective study was conducted of salivary gland tumors diag

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Doddrangaiah, Prakash Mylanahalli, Bharath Kanna Karunakaran, Roopa S. Mallali, and Afshan Fathima. "Clinicopathological profile of adenoid cystic carcinoma of minor salivary gland tumour: our experience at a tertiary care centre." International Journal of Otorhinolaryngology and Head and Neck Surgery 6, no. 8 (2020): 1460. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20203195.

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<p class="abstract"><strong>Background:</strong> Adenoid cystic carcinoma (ACC) is a rare malignant tumour originating from minor salivary glands. It is known for perineural spread, local recurrences and distant metastasis. The minor salivary gland tumour represents 3% of all head and neck neoplasms, whereas ACC constitutes about 0.5% of all malignant salivary gland neoplasms. This study was done to evaluate the clinical presentation and histopathological findings of minor salivary gland tumour.</p><p class="abstract"><strong>Methods:</strong> This stu

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Dwivedi, Gunjan, Sagar Gujrathi, and Amit Sood. "Acinic Cell Carcinoma of Buccal Mucosa Masquerading as Infratemporal Fossa Tumour: A Rare Case Report." Indian Cancer Awareness Journal 1 (March 23, 2022): 21–23. http://dx.doi.org/10.25259/icaj_3_2021.

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Acinic cell carcinoma (ACC) is a malignant epithelial salivary gland tumour. ACC commonly affects the parotid gland in 90% of cases. ACC rarely affects the minor salivary glands, but once affected it shows a less aggressive course. The purpose of this report is to present a rare case of ACC on minor salivary gland with an unusual presentation in an Indian male patient who was treated in our hospital.

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E, Deepika, and Dhivya K. "Pleomorphic Adenoma of The Palate – A Case Report And Review." International Journal of Contemporary Dental Research 2, no. 1 (2024): 6–13. http://dx.doi.org/10.62175/apdch2402.

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Pleomorphic Adenoma also known as mixed tumour, is one of the most common Neoplasms of the Salivary Gland. It consists of cells that can differentiate into epithelial and mesencephalic cells. The major Salivary gland that is affected by this tumor is the Parotid Gland. Among the minor salivary glands, Palate is the most frequently affected site. About 60% of all Pleomorphic Adenomas of Palates originate from this site. The majority of patients with this tumor are in the 30‟–50‟ age range. The most common manifestation of this tumor is slowly progressing asymptomatic Swelling. The diagnosis of

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Manerikar, Ravindra, Amit Mani, Manas Bajpai, and Shyam Reddy Karakalla. "Central Pleomorphic Adenoma of Mandible Mimicking Ameloblastoma – A Rare Case Report." Prague Medical Report 125, no. 2 (2024): 151–57. http://dx.doi.org/10.14712/23362936.2024.14.

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Salivary gland neoplasms account for 3% of all head and neck tumours. Pleomorphic adenoma (PA) is the most common salivary gland tumour that mainly occurs in the parotid gland, followed by minor salivary glands of the oral cavity, however, the occurrence of PA inside the jaw bones is exceedingly rare and very few cases have been reported in the literature. Inside jaw bones these lesions tend to imitate large osteolytic lesions encompass a diagnostic challenge. An exhaustive review of the literature revealed only 10 cases of central pleomorphic adenoma. We present a rare case of primary PA that

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Huq, AHMZ, M. Aktaruzzaman, MA Habib, MS Islam, and ASA Amin. "A comparative study between fine needle aspiration cytology findings and histopathological report of major salivary gland neoplasm in a tertiary hospital of Bangladesh." Bangladesh Medical Research Council Bulletin 39, no. 2 (2014): 69–73. http://dx.doi.org/10.3329/bmrcb.v39i2.19645.

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Salivary gland tumours are relatively uncommon and most of the tumours arise from parotid gland. Fine needle aspiration cytology (FNAC) is advised preoperatively as diagnostic tool but sometimes found to shown both false positive and false negative results. This study was aimed to find out distribution of neoplasm of major salivary glands and also to explore the sensitivity and specificity of FNAC. The present cross sectional study was done in the Dept. of Otolaryngology Head and Neck Surgery, BSMMU from January 2007 to December 2008. A total number of 60 gender-matched patients with major sal

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Jungehülsing, Markus, Matthias Wagner, and Michael Damm. "Turban tumour with involvement of the parotid gland." Journal of Laryngology & Otology 113, no. 8 (1999): 779–83. http://dx.doi.org/10.1017/s0022215100145190.

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AbstractFamilial autosomal dominant cylindromatosis (FADC, turban tumour syndrome, Brooke-Spiegler-syndrome and many more, MacKusick catalogue numbers 123850, 313100) is a rare hereditary disease usually presenting in the second or third decade. With female preponderance dermal cylindromas predominantly arise in hairy areas of the body with approximately 90 per cent on the head and neck. Transformation to malignancy seems to be scarce. Although cylindromas of the skin resemble basal cell adenomas of the salivary gland, there is usually no salivary gland involvement. On the other hand, patients

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Badia, Lydia, Justin N. Weir, and Anthony C. Robinson. "Heterotopic pleomorphic adenoma of the external nose." Journal of Laryngology & Otology 110, no. 4 (1996): 376–78. http://dx.doi.org/10.1017/s0022215100133675.

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AbstractPleomorphic adenomas arising from sites other than the major or minor salivary glands are uncommon. We describe a case of pleomorphic adenoma in the subcutaneous tissue of the nasomaxillary crease. An identical tumour was previously excised from the right nasal cavity. The possible aetiology of these heterotopic salivary gland tumours is discussed.

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Naima, Aziz, Rekha Das Roop, Sharma Antariksha, and Saikia Mayuri. "Role of FNAC in the Diagnosis of Salivary Gland Tumours." International Journal of Pharmaceutical and Clinical Research 15, no. 11 (2023): 591–95. https://doi.org/10.5281/zenodo.11217642.

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<strong>Background: </strong>Tumours of salivary gland constitute 1% to 5% of all head and neck tumours. Fine needle aspiration cytology (FNAC) is a cytodiagnostic method used for initial diagnosis of salivary gland swelling which is rapid, reliable, safe and inexpensive where individual or group of cells are studied to arrive at a pre-operative diagnosis.  The aim of this study is to evaluate cytological spectrum of salivary gland tumours and its correlation with age, gender and anatomical site. We have done a retrospective study of FNAC of salivary gland tumours for a period of 1 y

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Samar, María, Rodolfo Avila, Marta Furnes, et al. "Epithelioid Myoepithelioma of the Parotid Gland: A Histopathological and Immunohistochemical Study." International Journal of Medical and Surgical Sciences 1, no. 2 (2018): 177–83. http://dx.doi.org/10.32457/ijmss.2014.021.

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The diagnosis and classification of salivary gland tumours is complicated by the wide variety of histological types that exist. Many authors attribute this complexity to the myoepithelial component of these tumours. The objective of this study is to evaluate the histological and immunohistochemical properties of a parotid gland myoepithelioma, in order to further our understanding of the differential diagnosis of salivary gland tumours which contain myoepitheliocytes. Histological specimens were analyzed using haematoxylin and eosin (H&E), periodic acid Schiff (PAS), Cason, Alcian blue, to

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Zidar, N., N. Gale, A. Župevc, and M. Žargi. "Salivary gland tumours as second neoplasms: two cases and literature review." Journal of Laryngology & Otology 124, no. 5 (2009): 577–80. http://dx.doi.org/10.1017/s0022215109991526.

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AbstractObjectives:Patients who survive malignant tumours have an increased risk of second neoplasms, including those of the salivary glands. Mucoepidermoid carcinoma of the parotid gland is by far the most common type of second salivary gland tumour; other types have rarely been reported. We describe here two patients with a second tumour of the salivary glands.Case reports:The first patient was a 22-year-old woman with a low grade mucoepidermoid carcinoma of the parotid gland, which developed 21 years after completion of chemoradiotherapy for acute lymphoblastic leukaemia. The second patient

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Unger, Mark D., and Taras M. Gulyanich. "Parotid tumour presents as acute onset neck pain: a case report." International Journal of Otorhinolaryngology and Head and Neck Surgery 2, no. 2 (2016): 82. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20160959.

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<p class="abstract">Salivary gland tumors occur in the major and minor salivary glands. Major salivary gland tumors are frequently reported, with those arising in the parotid gland being most common. Patients with parotid tumors may be entirely asymptomatic. Some of the commonly reported symptoms directly related to parotid tumors include painless swelling of the parotid gland, ipsilateral facial palsy, and facial pain. This case report describes a clinically diagnosed parotid tumor presenting as ipsilateral, acute onset neck pain without preceding cervical trauma in the face of normal p

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Trendell-Smith, N. J., J. Oates, and J. Crocker. "The evaluation of salivary gland tumours using proliferating cell nuclear antigen." Journal of Laryngology & Otology 111, no. 6 (1997): 551–55. http://dx.doi.org/10.1017/s0022215100137880.

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AbstractIn order to assess its discriminating and prognostic value, we studied the immunoreactivity for proliferating cell nuclear antigen (PCNA) in tissue from 52 human salivary gland tumours using the murine monoclonal antibody PC10.The PCNA percentage count, namely, the average number of positive nuclei counted per 100 randomly selected tumour cells was recorded for each tumour. Anaplastic carcinoma was used as a positive control and histologically ‘normal’ salivary gland and tonsil served as a negative control.A PCNA count of 30 per cent was postulated to predict malignancy within a given

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Rahman, Sukri, Bestari Jaka Budiman, and Yolazenia Yolazenia. "PENATALAKSANAAN PLEOMORFIK ADENOMA PALATUM." Majalah Kedokteran Andalas 38, no. 1 (2015): 66. http://dx.doi.org/10.22338/mka.v38.i1.p66-72.2015.

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AbstrakPleomorfik adenoma merupakan tumor jinak campuran yang terdiri dari komponen sel epitel, mioepitel dan mesenkim yang tersusun dalam beberapa variasi. Tumor ini paling sering ditemukan pada kelenjar liur. Kelenjar liur mayor yang paling umum dikenai adalah kelenjar parotis, sedangkan kelenjar liur minor paling sering terjadi pada palatum. Terapi pilihan untuk pleomorfik adenoma kelenjar liur adalah reseksi tumor. Kasus ini diajukan agar dokter umum dan dokter spesialis Telinga, Hidung, Tenggorok dapat mengetahui diagnosis dan penatalaksanaan pasien dengan pleomorfik adenoma pada palatum.

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International, Journal of Medical Science and Innovative Research (IJMSIR). "Unravelling ectopic tumour pleomorphic adenoma of cheek - A Case Report." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 1 (2024): 131–35. https://doi.org/10.5281/zenodo.15369520.

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<strong>Abstract</strong> Pleomorphic adenoma is a benign tumor most commonly occurring in parotid gland. The tumour was originally believed to be “mixed” neoplastic cells derived from both duct epithelial cells and myoepithelial cells. However, it is now known to be a neoplasm of purely ectodermal cells. It affects most of the major as well as minor salivary glands. Palate is the most commonly affected minor salivary gland amongst other site followed by lips, cheeks, gingiva, floor of the mouth, and tongue. Pleomorphic Adenoma of buccal minor salivary glands is a very rare occurre

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Saini, Amit, Divyanshi Singh, Manisha Mahajan, and Disha Sharma. "Giant pleomorphic adenoma of submandibular gland: A case report." IP Journal of Surgery and Allied Sciences 5, no. 1 (2023): 24–26. http://dx.doi.org/10.18231/j.jsas.2023.006.

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Pleomorphic adenomas are the most common salivary gland tumours. It is rare to find these tumours in the submandibular glands. This case report is about a twenty-year old male patient who presented with huge mass on the submandibular region. The facial disfigurement due to the tumour was responsible for low self-esteem in this young male. The patient was treated with complete left submandibular gland excision.

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