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Bibliographies thématiques / Skilled forelimb use

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Littérature scientifique sur le sujet « Skilled forelimb use »

Auteur : Grafiati

Publié le 2 juin 2025

Mis à jour le 31 juillet 2025

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Articles de revues sur le sujet "Skilled forelimb use"

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Okabe, Naohiko, Naoyuki Himi, Emi Nakamura-Maruyama, et al. "Very Early Initiation Reduces Benefits of Poststroke Rehabilitation Despite Increased Corticospinal Projections." Neurorehabilitation and Neural Repair 33, no. 7 (2019): 538–52. http://dx.doi.org/10.1177/1545968319850132.

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Background. Although the effect of rehabilitation is influenced by aspects of the training protocol, such as initiation time and intensity of training, it is unclear whether training protocol modifications affect the corticospinal projections. Objective. The present study was designed to investigate how modification of initiation time (time-dependency) and affected forelimb use (use-dependency) influence the effects of rehabilitation on functional recovery and corticospinal projections. Methods. The time-dependency of rehabilitation was investigated in rats forced to use their impaired forelim

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Ruder, Ludwig, Riccardo Schina, Harsh Kanodia, Sara Valencia-Garcia, Chiara Pivetta, and Silvia. Arber. "A functional map for diverse forelimb actions within brainstem circuitry." Nature 590, no. 7846 (2022): 445–50. https://doi.org/10.1038/s41586-020-03080-z.

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The brainstem is a key centre in the control of body movements. Although the precise nature of brainstem cell types and circuits that are central to full-body locomotion are becoming known; 1-5; , efforts to understand the neuronal underpinnings of skilled forelimb movements have focused predominantly on supra-brainstem centres and the spinal cord; 6-12; . Here we define the logic of a functional map for skilled forelimb movements within the lateral rostral medulla (latRM) of the brainstem. Using in vivo electrophysiology in freely moving mice, we reveal a neuronal code with tuning of latRM po

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Antonow-Schlorke, Iwa, Julia Ehrhardt, and Marcel Knieling. "Modification of the Ladder Rung Walking Task—New Options for Analysis of Skilled Movements." Stroke Research and Treatment 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/418627.

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Method sensitivity is critical for evaluation of poststroke motor function. Skilled walking was assessed in horizontal, upward, and downward rung ladder walking to compare the demands of the tasks and test sensitivity. The complete step sequence of a walk was subjected to analysis aimed at demonstrating the walking pattern, step sequence, step cycle, limb coordination, and limb interaction to complement the foot fault scoring system. Rats (males,n=10) underwent unilateral photothrombotic lesion of the motor cortex of the forelimb and hind limb areas. Locomotion was video recorded before the in

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Allred, R. P., M. A. Maldonado, J. E. Hsu and, and T. A. Jones. "Training the "less-affected" forelimb after unilateral cortical infarcts interferes with functional recovery of the impaired forelimb in rats." Restorative Neurology and Neuroscience 23, no. 5-6 (2005): 297–302. https://doi.org/10.3233/rnn-2005-00315.

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Purpose: Unilateral lesions of the sensorimotor cortex (SMC) in adult rats cause major behavioral changes in the ipsilesional, "less-affected" forelimb. An increase in function and reliance on this forelimb can aid compensation for contralesional impairments, but may also promote disuse and reduced functionality of the impaired forelimb. We hypothesized that training focused on the ipsilesional forelimb following a unilateral SMC lesion would reduce the efficacy of later motor rehabilitative training of the impaired forelimb. Methods: Rats with ischemic SMC lesions were trained on a skilled re

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Rödter, Alexandra, Christian Winkler, Madjid Samii, and Guido Nikkhah. "Complex Sensorimotor Behavioral Changes after Terminal Striatal 6-OHDA Lesion and Transplantation of Dopaminergic Embryonic Micrografts." Cell Transplantation 9, no. 2 (2000): 197–214. http://dx.doi.org/10.1177/096368970000900206.

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In this study sensorimotor behavioral changes were monitored in rats following bilateral 6-hydroxydopamine (6-OHDA) axon terminal lesion and uni- or bilateral implantation of embryonic dopaminergic (DA) micrografts. A total of 28 μg of 6-OHDA was distributed over four injection tracts in the dorsolateral part of the caudate-putamen (CPU) bilaterally followed 4 months later by the implantation of DA micrografts spread over seven implantation tracts placed within the denervated area. Bilaterally 6-OHDA-lesioned animals exhibited significantly reduced behavioral performance scores in tests of exp

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Iwaniuk, AN, and IQ Whishaw. "How skilled are the skilled limb movements of the raccoon (Procyon lotor)?" Behavioural Brain Research 99 (June 7, 1999): 35–44. https://doi.org/10.1016/s0166-4328(98)00067-9.

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Raccoons have been widely used for neurobiological research and with respect to paw (hand) use have been 'considered' to be primates because they display highly developed skilled hand use. Their exceptional manipulatory ability is puzzling from an evolutionary perspective both because they belong to a taxon that is divergent from primates and because most members of their taxon are not especially skilled. Surprisingly, there has been no systematic investigation of their manipulatory ability. This was the purpose of the present study. Captive and zoo-housed raccoons were video recorded during f

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Mayer, Andrei, Márcio L. Nascimento-Silva, Natalia B. Keher, Ruben Ernesto Bittencourt-Navarrete, Ricardo Gattass, and João G. Franca. "Architectonic mapping of somatosensory areas involved in skilled forelimb movements and tool use." Journal of Comparative Neurology 524, no. 7 (2015): 1399–423. http://dx.doi.org/10.1002/cne.23916.

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Teskey, G. Campbell, Corey Flynn, Crystal D. Goertzen, Marie H. Monfils, and Nicole A. Young. "Cortical stimulation improves skilled forelimb use following a focal ischemic infarct in the rat." Neurological Research 25, no. 8 (2003): 794–800. http://dx.doi.org/10.1179/016164103771953871.

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Silasi, Gergely, Jamie D. Boyd, Federico Bolanos, Jeff M. LeDue, Stephen H. Scott, and Timothy H. Murphy. "Individualized tracking of self-directed motor learning in group-housed mice performing a skilled lever positioning task in the home cage." Journal of Neurophysiology 119, no. 1 (2018): 337–46. http://dx.doi.org/10.1152/jn.00115.2017.

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Skilled forelimb function in mice is traditionally studied through behavioral paradigms that require extensive training by investigators and are limited by the number of trials individual animals are able to perform within a supervised session. We developed a skilled lever positioning task that mice can perform within their home cage. The task requires mice to use their forelimb to precisely hold a lever mounted on a rotary encoder within a rewarded position to dispense a water reward. A Raspberry Pi microcomputer is used to record lever position during trials and to control task parameters, t

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Podraza, Katherine M., Yasmin Mehta, Vicki A. Husak, et al. "Improved functional outcome after chronic stroke with delayed anti-Nogo-A therapy: A clinically relevant intention-to-treat analysis." Journal of Cerebral Blood Flow & Metabolism 38, no. 8 (2017): 1327–38. http://dx.doi.org/10.1177/0271678x17730994.

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Many preclinical treatment strategies for stroke have failed when tested in human trials. Although the reasons for these translation failures are multifactorial, one potential concern is the statistical analysis of the preclinical data. One way to rigorously evaluate new therapies is to use an intention-to-treat analysis in preclinical studies. Therefore, in this study, we set out to evaluate the treatment efficacy of a potential clinically relevant therapeutic agent for stroke, i.e., anti-Nogo-A immunotherapy, using an intention-to-treat analysis. Adult rats were trained on the skilled foreli

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Chapitres de livres sur le sujet "Skilled forelimb use"

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Betz, Dene, April M. Becker, Katherine M. Cotter, Andrew M. Sloan, Ann M. Stowe, and Mark P. Goldberg. "Using Operant Reach Chambers to Assess Mouse Skilled Forelimb Use After Stroke." In Methods in Molecular Biology. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2926-0_22.

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Montoya, C. P., S. Astell, and S. B. Dunnett. "Chapter 51 Effects of nigral and striatal grafts on skilled forelimb use in the rat." In Progress in Brain Research. Elsevier, 1990. http://dx.doi.org/10.1016/s0079-6123(08)62634-5.

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