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Littérature scientifique sur le sujet « Sleep treatments »

Auteur : Grafiati

Publié le 17 mai 2023

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Articles de revues sur le sujet "Sleep treatments"

Kaplan, Katherine A. « Sleep and sleep treatments in bipolar disorder ». Current Opinion in Psychology 34 (août 2020) : 117–22. http://dx.doi.org/10.1016/j.copsyc.2020.02.001.

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Stein, Mark A., Margaret Weiss et Laura Hlavaty. « ADHD Treatments, Sleep, and Sleep Problems : Complex Associations ». Neurotherapeutics 9, n^o 3 (21 juin 2012) : 509–17. http://dx.doi.org/10.1007/s13311-012-0130-0.

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Cammaroto, Giovanni, Andrea Migliorelli et Claudio Vicini. « OSA : Treatments beyond CPAP ». Journal of Clinical Medicine 11, n^o 19 (8 octobre 2022) : 5938. http://dx.doi.org/10.3390/jcm11195938.

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Brietzke, Scott E., Eric J. Kezirian, Erica R. Thaler et B. Tucker Woodson. « Novel Sleep Apnea Surgical Treatments ». Otolaryngology–Head and Neck Surgery 147, n^o 2_suppl (août 2012) : P34. http://dx.doi.org/10.1177/0194599812449008a87.

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Palesh, O., K. Mustian, J. Roscoe, G. Morrow, M. L. Perlis, B. Issell, T. K. Banerjee et J. E. Delmore. « Prevalence and severity of sleep disturbance in 596 cancer patients : A URCC CCOP study ». Journal of Clinical Oncology 25, n^o 18_suppl (20 juin 2007) : 9016. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.9016.

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9016 Background: Sleep disturbance is a prevalent and, potentially, chronic problem among cancer patients, persisting for many months and years after treatments. As part of a multi-center longitudinal survey of patients beginning cancer treatments, we prospectively investigated the prevalence and severity of self-reported sleep disturbance. Methods: 596 Cancer patients (mean age=61; 66.4%=female) receiving chemotherapy and/or radiation (37.1%=chemotherapy, 40.1%=radiation therapy, 22.8%=both) from 17 NCI CCOPs reported whether they experienced any sleep disturbance using an 11-point Likert Scale (0 = “Not present” to 10 = “As bad as you can imagine”) prior to treatments, during treatments, and 6 months after finishing treatments. A side effect level 7 was considered “severe.” Results: Sleep disruption was reported by 31.9% (median=2; 10.6% severe) at baseline, 77.2% (median=4; 28.5% severe) during treatment and 65.1% (median=2; 15% severe) at 6 months post-treatment. Repeated-measures ANOVAs revealed statistically significant treatment group (chemotherapy, radiation, or both), age (< 61 or ≥ 61 yrs), and gender by time interactions (all p<0.05). Sleep disturbance was significantly higher among survivors in the two groups receiving chemotherapy, younger survivors, and women (all p<0.05). Sleep disruption increased from baseline to post-treatment and decreased from post-treatment to 6 months post-treatment (all p<0.05). There were no significant differences between baseline and 6 months post-treatment. Conclusions: These results show that difficulties with sleep increase during cancer treatment. Patients who are at higher risk for having sleep problems are women, younger patients, and patients undergoing chemotherapy. Supported by NCI Grants U10-CA37420 and R25-CA102618 No significant financial relationships to disclose.

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Khachatryan, Marine, Jenna Kay et Sejal Jain. « 704 The Association of Sleep Disorders in Patients with Chronic Pain Disorders ». Sleep 44, Supplement_2 (1 mai 2021) : A275. http://dx.doi.org/10.1093/sleep/zsab072.702.

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Abstract Introduction Sleep and pain are interrelated and have a bidirectional relationship. The study was performed to identify the impact of sleep disorders on pain perception. Methods The institutional review board approved the study. Patients evaluated in the Pain Clinic between 1/1/2014 and 12/31/2017 who had polysomnography done were identified by database search. Chart review identified demographics, initial pain score, pain treatments, sleep disorder diagnosis, treatments of sleep disorder and pain scores after sleep treatments. Numerical pain score (NPS) and insomnia severity index (ISI) were used as a measure of pain and sleep quality, respectively. The descriptive statistics were presented by percentages, mean and standard deviations. Regression analysis was performed between initial NPS and ISI. T-test compared change in NPS for compliant and non-compliant subjects, before and after sleep treatments. Linear regression model identified factors associated with changes in pain perception after sleep treatments. Results Of the 320 participants identified, complete data was available for 180 subjects. The average age was 55.9±13.9; 51.41% were female; 60.2% were Caucasian and 26.64% were Hispanic. Initial NPS was 8.8±1.7, average ISI was 15.00±6.41, average BMI was 35.4±10.2. Ninety-five percent had a diagnosis of obstructive sleep apnea (OSA), 27.81% had restless leg syndrome, and 7.19% had complex sleep apnea. Since most patients had OSA, details of positive airway pressure (PAP) treatments were also investigated. Of 84% of subjects treated with PAP, compliance data were available for 53%, which showed 69% (n=55) being complaint with PAP. Initial NPS correlated positively with ISI (R2: 0.064±0.024, p<0.01). No difference in NPS was found in groups based on compliance, before and after PAP treatments. Regression model identified that BMI was the most significant factor in the change in NPS following sleep treatment (R2: 0.083±0.034, p = 0.03). Conclusion The study identified that the severity of pain is associated with poor quality of sleep. While this study failed to identify improvement in pain perception after successful OSA treatment, limited number of subjects in our study were compliant with PAP treatment which may have impacted the results. Future prospective studies are needed to understand the complex association between improvement in sleep quality and pain perception. Support (if any):

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Mitteldorf, Darryl, et Jerrod Nelms. « Are prostate cancer treatments correlated to sleep distress ? » Journal of Clinical Oncology 36, n^o 6_suppl (20 février 2018) : 347. http://dx.doi.org/10.1200/jco.2018.36.6_suppl.347.

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347 Background: Sleep distress associated with prostate cancer due to emotional issues like anxiety is well documented. But there have been no investigations focused on sleep distress correlated to specific types of prostate cancer treatments. Methods: During a ten day period in July, 2016, 963 men diagnosed with prostate cancer completed an online survey containing demographic and treatment history questions, the Pittsburg Sleep Quality Index (PSQI) and a current state of health self-assessment. The subjects were randomly chosen from the Malecare prostate cancer support network in the United States and completed the survey. 27% of survey subjects reported being initially diagnosed with Gleason 8 or higher. 42% reported using either androgen deprivation therapy, Zofigo, Xtandi or Xofigo within three months of our survey. Only 5% had been continually on active surveillance. We compiled the PSQI Component score and correlated the scores to a specific prostate cancer treatments, adjudicating for pre-existing conditions such as emotional disorders or apnea. We stratified for race, age, sexual orientation and if the subject had a sleep partner. Results: The PSQI handout says that a total score of 5 or greater indicates sleep distress worthy of consultation with a healthcare provider. Our investigation also considered a “4” to indicate poor sleep quality among participants. Only 398 (41.33%) of our participants scored less than 5 on the PSQI, while only 232 (24.09%) scored less than 4. From these statistics, we showed that over 75% of our study sample suffered sleep distress. However, our analysis failed to disclose significant correlations between specific types of prostate cancer treatments and extent of sleep distress. We did not see correlations regarding subject’s age, race, sleep co-habitation, time from diagnosis to survey and other treatment and demographic stratifications. Conclusions: Sleep distress is well established and broadly experienced by prostate cancer patients. Our study showed there is no advantage to any specific prostate cancer treatment in terms of sleep distress. We also found that severity and instances of sleep distress are distributed without significance across age, race, sexual orientation and time to treatment after diagnosis.

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Kaufmann, Christopher N., Mark W. Bondi, James D. Murphy, Xin Tu et Alison A. Moore. « COGNITIVE TRAJECTORIES BEFORE AND AFTER SLEEP TREATMENT INITIATION IN U.S. OLDER ADULTS WITH SLEEP DISTURBANCE ». Innovation in Aging 3, Supplement_1 (novembre 2019) : S403—S404. http://dx.doi.org/10.1093/geroni/igz038.1499.

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Abstract Sleep disturbances are associated with cognitive decline but it is not clear if initiation of sleep treatments mitigates decline. We used the 2006-2014 Health and Retirement Study. At each wave, participants were administered cognitive assessments and scores were summed (values=0-35; higher=better cognition). All participants also reported if, in the past two weeks, they had taken medications or used other treatments to improve sleep. Our sample (N=4,650) included individuals who at baseline were cognitively normal and untreated for sleep, and at any wave reported some sleep disturbance. We characterized cognitive performance over study period with comparisons before and after sleep treatment initiation. Between 2006-2014, participants exhibited declines in cognitive performance (B=-2.40; 95% CI=-2.73, -2.06; p<0.001) after controlling for confounders. Following sleep treatment, cognitive decline became less pronounced (interaction B=0.94; 95% CI=0.21, 1.67; p=0.013). Results suggest that in older adults with sleep disturbance, initiation of sleep treatment may slow cognitive decline.

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Cacciatore, Martina, Francesca G. Magnani, Matilde Leonardi, Davide Rossi Sebastiano et Davide Sattin. « Sleep Treatments in Disorders of Consciousness : A Systematic Review ». Diagnostics 12, n^o 1 (31 décembre 2021) : 88. http://dx.doi.org/10.3390/diagnostics12010088.

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Sleep disorders are among the main comorbidities in patients with a Disorder of Consciousness (DOC). Given the key role of sleep in neural and cognitive functioning, detecting and treating sleep disorders in DOCs might be an effective therapeutic strategy to boost consciousness recovery and levels of awareness. To date, no systematic reviews have been conducted that explore the effect of sleep treatments in DOCs; thus, we systematically reviewed the existing studies on both pharmacological and non-pharmacological treatments for sleep disorders in DOCs. Among 2267 assessed articles, only 7 were included in the systematic review. The studies focused on two sleep disorder categories (sleep-related breathing disorders and circadian rhythm dysregulation) treated with both pharmacological (Modafinil and Intrathecal Baclofen) and non-pharmacological (positive airway pressure, bright light stimulation, and central thalamic deep brain stimulation) interventions. Although the limited number of studies and their heterogeneity do not allow generalized conclusions, all the studies highlighted the effectiveness of treatments on both sleep disorders and levels of awareness. For this reason, clinical and diagnostic evaluations able to detect sleep disorders in DOC patients should be adopted in the clinical routine for the purpose of intervening promptly with the most appropriate treatment.

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Bailey, Grace A., Emily K. Hubbard, Alfonso Fasano, Marina AJ Tijssen, Timothy Lynch, Kirstie N. Anderson et Kathryn J. Peall. « Sleep disturbance in movement disorders : insights, treatments and challenges ». Journal of Neurology, Neurosurgery & ; Psychiatry 92, n^o 7 (19 mars 2021) : 723–36. http://dx.doi.org/10.1136/jnnp-2020-325546.

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Sleep and circadian rhythm disturbances are central features of many movement disorders, exacerbating motor and non-motor symptoms and impairing quality of life. Understanding these disturbances to sleep is clinically important and may further our understanding of the underlying movement disorder. This review evaluates the current anatomical and neurochemical understanding of normal sleep and the recognised primary sleep disorders. In addition, we undertook a systematic review of the evidence for disruption to sleep across multiple movement disorders. Rapid eye movement sleep behaviour disorder has emerged as the most reliable prodromal biomarker for the alpha synucleinopathies, including Parkinson’s disease and multiple system atrophy, often preceding motor symptom onset by several years. Abnormal sleep has also been described for many other movement disorders, but further evidence is needed to determine whether this is a primary or secondary phenotypic component of the underlying condition. Medication used in the treatment of motor symptoms also affects sleep and can aggravate or cause certain sleep disorders. Within the context of movement disorders, there is also some suggestion of a shared underlying mechanism for motor and sleep pathophysiology, with evidence implicating thalamic and brainstem structures and monoaminergic neurotransmission. This review highlights the need for an understanding of normal and abnormal sleep within the movement disorder clinic, an ability to screen for specific causes of poor sleep and to treat sleep disturbance to improve quality of life. Key sleep disorders also act as important biomarkers and have implications in diagnosis, prognosis and the development of future therapies.

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Thèses sur le sujet "Sleep treatments"

Moss, James. « Physiological effects of treatments in obstructive sleep apnoea syndrome ». Thesis, Sheffield Hallam University, 2013. http://shura.shu.ac.uk/20763/.

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The original research in this thesis aimed to investigate physiological effects of different treatment approaches in obstructive sleep apnoea syndrome (OSAS). OSAS is a prevalent public health concern independently associated with increased cardiovascular risk. Specifically, study 1 examined the feasibility of conducting a pragmatic lifestyle intervention in patients reporting compliance with continuous positive airway pressure (CPAP) and collected provisional data about its efficacy, and study 2 investigated the physiological effects of low compliance to CPAP therapy in a four-arm observational study. The intervention in study 1 involved supervised exercise, dietary advice and behaviour change counselling. Primary outcome measures were recruitment, retention and compliance data and secondary outcome measures assessed anthropometrics, cardiovascular risk, quality of life and exercise capacity. Study 2 investigated macro-and microvascular function, anthropometrics, quality of life, cardiovascular risk and exercise capacity. The novel findings of this research were: 1) the lifestyle intervention was feasible to deliver; 2) the intervention improved key health outcomes such as exercise capacity (A +16%) and serum C-reactive protein (A -57%), which were maintained after 3 months of independence (A +22% and -57%, respectively); 3) self-reported CPAP compliance is an unreliable indicator of actual compliance; 4) it is difficult to recruit low-compliance patients onto research trials, and recruiting newly diagnosed patients is also difficult without interrupting the patient pathway; 5) vascular function seems impaired in low-compliance patients versus high-compliance patients, although further work is needed to confirm this. These findings contribute to the growing evidence base for the role of lifestyle intervention in OSAS, and provide provisional data on the effects of low compliance to CPAP therapy on vascular endothelial function. In summary, future research investigating pragmatic lifestyle interventions in OSAS and the physiological effects of low-compliance to CPAP is certainly warranted.

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Espie, Colin A. « A controlled comparative investigation of psychological treatments for chronic sleep-onset insomnia ». Thesis, University of Glasgow, 1987. http://theses.gla.ac.uk/822/.

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Seventy, GP-referred, sleep-onset insomniacs were randomly assigned to either progressive relaxation, stimulus control, paradoxical intention, placebo or no treatment control groups. Following baseline assessment of sleep pattern and quality subjects received 8 weeks of treatment, comprising 4 weeks under counterdemand and 4 weeks under positive demand instruction to control for demand characteristics and expectancy effects. A further 14 patients were allocated consecutively to a tailored therapy condition as a development of the main study. Measures of treatment process and outcome were obtained from self-report instruments validated against objective monitoring via the `Somtrak

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Crawford, Megan R. « Behavioural adherence in the treatments of disorders of sleep and wakefulness : a biopsychosocial approach ». Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4191/.

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Obstructive sleep apnoea (OSA) and insomnia are the two most prevalent sleep disorders. Their respective treatments Continuous Positive Airway Pressure (CPAP) and Cognitive Behaviour Therapy for insomnia (CBT-I), are effective, but at the same time challenging. It is this challenge that may translate to poor adherence, which ultimately leads to a reduction in treatment effectiveness. The evaluation of these treatments should not fall short of understanding effectiveness by only considering efficacy; the effort to establish what influences adherence makes up a large part of that goal. The aim of this thesis is to contribute to the literature by adopting a biopsychosocial approach (BPS). That is, the consideration of biomedical, psychological and social factors and how they interact to influence behaviour. The implications for both CPAP and CBT-I adherence literature were tested in the context of four experimental studies. Semi-structured interviews were conducted with 11 CPAP users, with 5 individuals completing the three required interviews prior to, at 1 week and 3 months after treatment initiation. The core themes emerging from a thematic analysis were ‘internal conflict around acceptance and adherence’, ‘integration of CPAP into life’ and ‘motivators and resources for CPAP use’. The interviews with 11 individuals having completed a CBT-I program revealed three important issues: ‘Making sense of CBT-I’, ‘Ongoing evaluation of components’ and ‘Obstacles to implementation’. Both studies reveal potential psychological and social factors contributing to adherence to CPAP and CBT-I, which need to be considered in a BPS framework. A patient-level meta-analysis of three randomised placebo-control studies showed that the relationship between CPAP adherence and improvements in daytime sleepiness was caused by both physiological (high use of real CPAP reduced sleepiness more than high use of placebo and more than low use of real CPAP) and psychological effects (high use of placebo was superior to low use of placebo), possibly as a result of an expectation of benefit. The results support the importance of considering both biomedical and psychosocial factors and their interactive effects on adherence. The translation of the BPS approach to clinical practice will be facilitated by the development of brief, reliable and valid measures to assess psychological iii and social variables in addition to the existing biomedical tools. The Stage of Change Scale for Insomnia (SOCSI) assessing components of the transtheoretical model (stage of change, self-efficacy, decisional balance and processes of change), was constructed and cognitively pre-tested in 13 individuals completing CBT-I. The reliability and validity of this comprehensible scale was subsequently examined in the context of a sleep restriction trial. Insomnia-related symptoms at post-treatment and follow-up, which were significantly different from baseline in the 27 individuals with insomnia, were associated with actigraphdetermined adherence to the agreed bed window. The SOCSI was deemed a valid tool with participants in the self-identified action/maintenance stage revealing significantly better adherence, higher motivation and self-efficacy than those in the contemplation and preparation stage. Test-retest reliability of the SOCSI was excellent and the content analysis of open-box responses revealed information for further validation of decisional balance and processes of change scales. This thesis provides novel information about the variables that influence adherence to CPAP and CBT-I. It distinguishes itself from previous efforts by acknowledging the need for the adoption of a BPS framework. This approach is necessary to successfully advancing not only the CPAP and CBT-I adherence literature individually, but potentially the adherence field in general.

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Billiards, Saraid Sheelagh. « Neurosteroid and somnogenic responses to endotoxin and hypoxia treatments in lambs ». Monash University, Dept. of Physiology, 2003. http://arrow.monash.edu.au/hdl/1959.1/9553.

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Lundin, Roger, et Maria Nissinen. « Att främja nattsömnen : En allmän litteraturöversikt över vårdåtgärder vid demens ». Thesis, Mälardalens högskola, Akademin för hälsa, vård och välfärd, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-47606.

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Background: Dementia is a common disease today and about 10% of the population in Sweden develop dementia. Dementia is associated with cognitive problems and troublesome symptoms, and is evident in the patient as the disease progresses. Problems: Sleep disorders can be a major problem for people with dementia, their relatives and even the healthcare staff. As a consequence of sleep disorders negative symptoms like agitation, depression and apathy can be enhanced. This leads to a greater workload for the healthcare staff and more effort emotionally for the relatives. Purpose: The purpose is to describe interventions that improves night sleep in people with dementia. Method: A literature review. The basis consists of 13 articles with both qualitative and quantitative approach. Result: Three categories appeared where night sleep might be promoted through activities, treatments and closeness. In addition to the enhanced night's sleep, the results also showed that improvement in agitation, depression and apathy might be achieved through these interventions. Conclusion: Night sleep in people with dementia can be improved through the interventions reported in the results. The result indicate that in order to perform good care the interventions have to be based on individual conditions.
Bakgrund: Demens är idag en folksjukdom och omkring 10 % av befolkningen i Sverige utvecklar demens. Till demenssjukdomen hör kognitiv problematik samt besvärande symtom och framträder hos den sjuke allt eftersom sjukdomen fortskrider. Problem: Sömnstörningar kan vara ett stort problem för människor med demens, dess anhöriga och även vårdpersonal. Som en konsekvens av sömnstörningar kan negativa symtom såsom agitation, depression och apati förstärkas. Detta leder till större arbetsbörda för vårdpersonalen och mer ansträngning emotionellt för de anhöriga. Syftet: Att beskriva vårdåtgärder som främjar nattsömnen hos människor med demens. Metod: En allmän litteraturöversikt där underlaget består av 13 studier som ligger som grund till resultatet. Resultatet: Det framkommer tre kategorier där nattsömnen kan främjas genom aktiviteter, behandlingar och närhet hos människor med demenssjukdom. Utöver den främjade nattsömnen visade resultatet även att förbättring på agitationen, depressionen och apatin kan ske med hjälp av åtgärderna. Slutsats: Nattsömnen hos människor med demens kan främjas genom vårdåtgärderna som redovisas i resultatet. Resultatet indikerar dock att åtgärderna måste utföras utifrån individuella förutsättningar för att på bästa sätt kunna utföra en god vård.

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gaddam, sathvika, Ali Bokhari et Deepika 7471363 Nallala. « ACROMEGALY TREATMENT AND RESOLUTION OF SLEEP APNEA ». Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/41.

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Introduction Acromegaly is an endocrine disorder characterized by excessive growth hormone production.The most common cause is a benign pituitary adenoma, which can be an isolated tumor or part of a group of concomitant endocrine neoplasms. We present a case of a middle aged woman with sleep apnea and a newly diagnosed acromegaly secondary to a pituitary macroadenoma. Case presentation A 51-year-old woman was seen in the endocrinology clinic for evaluation of hyperparathyroidism and mild hypercalcemia. She had no symptoms related to hypercalcemia. However, she complained of enlargement of her fingers and toes. She also reported galactorrhea and breast engorgement. There was no hyperhidrosis or frontal bossing present and she denied headaches or vision symptoms. Past medical history was significant for obstructive sleep apnea. Insulin like growth factor level was 630 ng/ml (reference 53 - 190 ng/ml), prolactin level was 109 ng/ml (reference 1.9- 25 ng/ml), and Follicular stimulating hormone was 0.4mIU/ml (reference 1.2 - 21.0 mIU/ml). TSH, free T4, ACTH, and cortisol were normal. The labs were consistent with pituitary macroadenoma secreting growth hormone (GH) and prolactin. MRI pituitary showed a 1.9 cm macroadenoma with no evidence of optic nerve compression. Due to the coexisting diagnoses of hyperparathyroidism and pituitary adenoma, CT abdomen was done to evaluate for neuroendocrine tumor and to rule out Multiple Endocrine Neoplasia (MEN) Type 1. She then underwent transsphenoidal resection of the pituitary, with immunostaining reflecting diffuse prolactin and patchy GH expression. Post-surgery IGF, prolactin, thyroid function tests were normal. She was started on hydrocortisone replacement due to abnormal ACTH and cortisol. Her calcium levels normalized, and further genetic testing for MEN was abandoned. Her repeat sleep study also showed resolution of sleep apnea. She did not suffer from further symptoms of acromegaly and was scheduled for periodic surveillance for thyroid axis dysfunction. Discussion Dysregulated growth hormone production seen in acromegaly leads to increased GH and IGF-1 levels. It has many ramifications including debilitating arthritis from osteoarthropathy, glucose intolerance due to insulin resistance, higher propensity for GI neoplasms, and macroglossia with prognathism causing sleep apnea. Average lifespan is decreased by 30% due to cardiovascular and pulmonary dysfunction. Treatment is aimed at decreasing IGF levels and controlling any mass effect or metabolic abnormalities caused by the tumor. Treatment options include invasive procedures for good surgical candidates and medical therapy via somatostatin analogue for patients who are not. Residual or unresectable tumors can be treated with medical therapy or radiation therapy if there is no response to medication.

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Waters, Karen Ann. « Sleep disordered breathing and its treatment in children ». Thesis, The University of Sydney, 1993. https://hdl.handle.net/2123/26603.

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The establishment of a dedicated paediatric sleep unit over the past three years has allowed detailed investigation of a large number of children with sleep associated upper airway obstruction. This thesis explores the characteristics of upper airway obstruction and sleep associated breathing control abnormalities, in children who have been investigated in that unit. The "unit" began with three or four people performing children’s sleep studies at the Sleep Unit (for adults) at RPAH; the results presented here include those studies. The methods used in this thesis have evolved through practical experience acquired in caring for children with breathing disorders in sleep. This thesis is presented in two parts. The studies in the ﬁrst section provide an overview of the presentation and treatment of the syndrome of obstructive sleep apnoea (OSA) as it occurs in infants and children. The second section is a more detailed exploration of OSA and its treatment in achondroplasia. These latter studies provide further insights into the disorder in this speciﬁc group, and therefore into some aspects of OSA in the broader population of children.

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Durant, Claire Fiona. « Brain and endocrine mechanisms of sleep disruption : sleep and refractory depression ; new approaches to treatment and their effect on sleep ». Thesis, University of Bristol, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.574415.

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Sleep disturbance is a distressing and often poorly treated core symptom of major depression. Physiological sleep abnormalities are one of the few biological markers in depression. Reported here are studies in which sleep has been used to further our understanding of two experimental treatments for patients with treatment refractory depression (TRD). The first is a crossover study of the effect of two bolus infusions of hydrocortisone administered in the afternoon on sleep that night in healthy volunteers. This study was undertaken to help interpret results in a comparable patient study, in which the effects of 3 daily, high doses of hydrocortisone on sleep were assessed on night 3 (after hydrocortisone treatment), and 4 weeks later in patients with TRD. In healthy volunteers, hydrocortisone significantly increased slow wave sleep and, in a dose dependent manner, suppressed rapid eye movement sleep (REM), despite a delay of 8-10 hours between infusion and start of sleep recordings. The low dose increased measures of arousal, resulting in delayed sleep onset. In the patient study, it was not possible to confirm any sleep effects of hydrocortisone at a group level because of low patient numbers and large baseline variations in sleep measures attributable to psychotropic medications with differing effects on sleep architecture. However, the data gave some indication that if sleep improvements were observed directly after hydrocortisone, these were sustained, although not necessarily accompanied by mood alterations. The third study was an investigation of sleep effects of deep brain stimulation (DBS) in patients with TRD. Intracerebral electrodes were implanted in the subgenual cingulate (SGC) and nucleus accumbens (NAcc) regions. Continuous stimulation was commenced in one target brain region (randomised order) which could be switched to the second if no clinical response was observed. The main finding was a striking increase in REM sleep and reduction of REM onset latency after acute SGC stimulation, but not with NAcc stimulation. These results could imply previously unknown cortical mechanisms of REM sleep modulation

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Mehta, Atul S. « Treatment of snoring and obstructive sleep apnoea using a mandibular advancement splint ». Master's thesis, Faculty of Dentistry, 1998. http://hdl.handle.net/2123/4904.

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This work was digitised and made available on open access by the University of Sydney, Faculty of Dentistry and Sydney eScholarship . It may only be used for the purposes of research and study. Where possible, the Faculty will try to notify the author of this work. If you have any inquiries or issues regarding this work being made available please contact the Sydney eScholarship Repository Coordinator - ses@library.usyd.edu.au

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Yang, Qiao. « The effects of acute and short-term continuous positive airway pressure treatment withdrawal on sleep and neurobehavioural function in patients with obstructive sleep apnea ». Thesis, The University of Sydney, 2007. https://hdl.handle.net/2123/28138.

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This study systematically examined the changes in sleep parameters, neurobehavioural performance and markers of objective and subjective sleepiness after an acute (one night) and short-term (seven nights) period of withdrawal from Continuous Positive Airway Pressure (CPAP) treatment in patients with obstructive sleep apnea (OSA). The effects of one night of CPAP reintroduction immediately following CPAP withdrawal on these parameters were also investigated. CPAP treatment can effectively eliminate upper airway obstruction at night but patients frequently withdraw from CPAP therapy for short periods. The effects of intermittent CPAP use on sleep and subsequent neurobehavioural function have not been systematically examined. It is important to determine the neurobehavioural effects of short-term CPAP withdrawal. Using a repeated-measurement-within-subject design, 20 participants receiving optimal, long-term CPAP therapy were withdrawn from routine CPAP therapy. Polysomnograms were performed on NO (with CPAP), N1 and N7 (without CPAP) and N8_R (with CPAP). Acute CPAP withdrawal resulted in the recurrence of sleep-disordered breathing (SDB) with sleep disruption, hypoxemia and increased subjective sleepiness. Short-term CPAP withdrawal exacerbated hypoxemia and increased delta activity in EEG quantified by power spectral analysis. Protracted time off CPAP also increased subjective and objective sleepiness, and poor mood ratings. Autonomic arousals measured using respiratory-related reductions in finger blood volume by peripheral arterial tonometry (PAT) decreased from N1 to N7. Neurobehavioural functioning assessed using the psychomotor vigilance task was impaired following N7 and associated with hypoxemia and changes in morning tumour necrosis factor-alpha (TNF-a) levels. However, other neurobehavioural measures were not affected. Simulated driving performance was also unaffected. Interestingly, despite this, EEG recordings demonstrated neurophysiological evidence of increased sleepiness and greater time-on-task induced EEG changes. Resumption of CPAP treatment on N8_R eliminated most airway obstruction, maintained oxygenation, reversed daytime sleepiness and some vigilance decrements. The immediate benefits of CPAP treatment on sleep consolidation and subjective sleepiness were marked.

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Livres sur le sujet "Sleep treatments"

Baron-Faust, Rita. Sleep disorders : Common problems & treatments. Norwalk, CT : Belvoir Media Group, 2009.

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Baron-Faust, Rita. Sleep disorders : Common problems & treatments. Norwalk, CT : Belvoir Media Group, 2009.

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Behavioral treatments for sleep disorders : A comprehensive primer of behavioral sleep medicine interventions. Amsterdam : Academic, 2011.

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Ian, St James-Roberts, Harris Gillian et Messer David J. 1952-, dir. Infant crying, feeding, and sleeping : Devleopment, problems, and treatments. New York : Harvester Wheatsheaf, 1993.

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Gillian, Harris, Messer David J. 1952- et St James-Roberts Ian, dir. Infant crying, feeding and sleeping : Development, problems and treatments. New York : Harvester Wheatsheaf, 1993.

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Steven, Poceta J., et Mitler Merrill Morris 1945-, dir. Sleep disorders : Diagnosis and treatment. Totowa, N.J : Humana Press, 1998.

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Can't sleep, won't sleep. Milverton [England] : Capall Bann, 2005.

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Sacchetti, Lisandro M., et Priscilla Mangiardi. Obstructive sleep apnea : Causes, treatment and health implications. New York : Nova Science Publishers, 2012.

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Sleep solutions. London : Ward Lock, 1999.

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Guglietta, Antonio, dir. Drug Treatment of Sleep Disorders. Cham : Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-11514-6.

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Chapitres de livres sur le sujet "Sleep treatments"

Means, Melanie K., et Margaret D. Lineberger. « Nonpharmacological Treatments ». Dans Sleep Disorders in Neurology, 74–83. Oxford, UK : Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444315158.ch7.

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Spielman, Arthur J., et Paul B. Glovinsky. « A History of Nonpharmacological Treatments for Insomnia ». Dans Sleep Medicine, 519–26. New York, NY : Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2089-1_58.

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Dokucu, Mehmet E. « Pharmacological Treatments of Insomnia ». Dans Sleep Disorders in Women, 121–34. Totowa, NJ : Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-324-4_9.

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Mary, Rose. « Non-Pharmacological Treatments of Insomnia and Circadian Rhythm Disorder ». Dans Sleep Medicine in Neurology, 90–102. Oxford : John Wiley & Sons, 2013. http://dx.doi.org/10.1002/9781118764152.ch9.

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Posner, Donn, et Philip R. Gehrman. « Sleep Hygiene ». Dans Behavioral Treatments for Sleep Disorders, 31–43. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-12-381522-4.00003-1.

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Lichstein, Kenneth L., S. Justin Thomas et Susan M. McCurry. « Sleep Compression ». Dans Behavioral Treatments for Sleep Disorders, 55–59. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-12-381522-4.00005-5.

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Auckley, D. « SLEEP APNEA | Drug Treatments ». Dans Encyclopedia of Respiratory Medicine, 59–63. Elsevier, 2006. http://dx.doi.org/10.1016/b0-12-370879-6/00361-6.

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Spielman, Arthur J., Chien-Ming Yang et Paul B. Glovinsky. « Sleep Restriction Therapy ». Dans Behavioral Treatments for Sleep Disorders, 9–19. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-12-381522-4.00001-8.

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Doghramji, Karl, et Anna Ivanenko. « Sleep-Wake Disorders ». Dans Gabbard’s Treatments of Psychiatric Disorders. American Psychiatric Publishing, 2014. http://dx.doi.org/10.1176/appi.books.9781585625048.gg36.

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Berry, Richard B. « Obstructive Sleep Apnea Treatment Overview and Medical Treatments ». Dans Fundamentals of Sleep Medicine, 299–312. Elsevier, 2012. http://dx.doi.org/10.1016/b978-1-4377-0326-9.00018-x.

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Actes de conférences sur le sujet "Sleep treatments"

Butler, D., I. Makariou, M. Scoto, V. Gowda, M. Fernandez, E. Wraige, H. Jungbluth, F. Muntoni, H. Tan et F. Trucco. « Sleep outcomes in spinal muscular atrophy and role of disease-modifying treatments. » Dans ERS International Congress 2022 abstracts. European Respiratory Society, 2022. http://dx.doi.org/10.1183/13993003.congress-2022.1516.

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Artene, Diana. « FAT LOSS SOLUTIONS FOR OVERWEIGHT BREAST CANCER PATIENTS WITH SLEEP DISTURBANCES ». Dans Brazilian Breast Cancer Symposium 2022. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s2027.

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Objective: Obese breast cancer patients obtain lower pathological complete response rates and experience more neuropathy, anemia, fatigue, and depression during chemotherapy; have more surgical complications such as infection, seroma, implant loss, and lymphedema; more radiation dermatitis and esophagitis; lower disease-free survival and overall survival plus more grade 3 and 4 side effects under anti-HER2 treatments; lower Fulvestrant and Anastrozole efficacy; and more AET-related and Alpelisib side effects; the main impact coming from the fact that these are the main causes of treatment non-adherence and discontinuation. Due to the detrimental metabolic and behavioral impact, the quality of sleep is one of the important patient-related factors that needs to address when addressing obesity-related causes to improve oncologic outcomes. Methods: Seeking fat loss solutions for overweight ER+ breast cancer patients with sleep disturbances, we randomized 50 patients — of which 16 were depressive — to follow a high protein diet (D) or the diet and sleep journal interventions (D+SJ) for 8 weeks. Patients ate only when they were hungry, ate foods that were high in protein, calcium, omega-3, pre-, and probiotics, and wrote a daily food journal. Half of the patients were asked to write a 7-day SJ: the time it took them to fall asleep, the number of awakenings during the night, how much they slept, how much they stayed in bed, and self-perceived sleep quality. They were asked to set their sleeping and wake-up hours based on their SJ answers and to not sleep during the day. Eight patients from the D+SJ group left the study, five being depressive. We measured body composition with a bioelectrical impedance analysis scale. Results: The D group lost 2.31±2.86% of body fat (p=0.000) and 0.76±1.16% of visceral fat (p=0.000) with no differences between patients with or without depression. The D+SJ group improved sleep quality and lost 2.16±2.35% of body fat (p=0.002) and 0.86±1.24% of visceral fat (p=0.005); but depressive patients did not obtain statistically significant results, which may be because of the overtiring effect of the SJ intervention. So, both D and D+SJ interventions improve breast cancer patients’ body composition despite sleep disturbances. Conclusion: SJ interventions improve sleep quality in patients without depression, thereby decreasing weight regain risk.

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Mylavarapu, Goutham, Ephraim Gutmark, Mihai Mihaescu et Shanmugam Murugappan. « Simulation of Flow and Structural Dynamics in Human Upper Airways ». Dans ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19501.

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Obstructive Sleep Apnea and Hypo Apnea Syndrome (OSAHS) is a respiratory disorder characterized by repeated episodes of partial or complete airway obstruction. OSAHS is also associated with decreased quality of life, decreased cardiovascular health, day-time sleepiness, and increased transportation accidents. Its high prevalence with as much as 4% of American population suffering from OSAHS also makes it an important health care issue[1]. Existing surgical treatments suffer from a moderate to high successful failure rates. Broader research on this respiratory disorder for a better understanding of the pathophysiology of human upper airway, to develop better diagnostic methods and treatment modalities is very much needed.

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Rosko, Sanja Pejic, Lana Lončar, Jadranka Sekelj Fureš, Ivana Đaković, Vlasta Đuranović et Katarina Vulin. « 399 Electrical status epilepticus in sleep (ESES):Clinical and EEG characteristics and response to treatments ». Dans 10th Europaediatrics Congress, Zagreb, Croatia, 7–9 October 2021. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2021. http://dx.doi.org/10.1136/archdischild-2021-europaediatrics.399.

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Zhang, Z. F., et A. M. Al-Jumaily. « A Novel Constant Bias Flow Rate CPAP Mask for OSA Therapy Treatments ». Dans ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-16057.

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Continuous positive airway pressure (CPAP) therapy is considered the most effective treatment for patients with Obstructive Sleep Apnea (OSA) symptom. A CPAP mask is the interface between the patient and the CPAP humidifier, which contains a series of orifice to circulate the air and ensure that the expired carbon dioxide from the patient's breathing is not rebreathed. The flow through those orifices is called bias flow. For the existing CPAP mask, this bias flow rate increases as the CPAP pressure increases. This raised bias flow rate usually causes a bigger pressure swing inside the mask when the patient is breathing, which is unfavorable for OSA therapy due to the much bigger breathing load required. However, a minimum bias flow rate needs to be maintained inside the mask in order to keep carbon dioxide concentration low. Therefore, this paper introduces a novel mask that can produce a relatively constant bias flow rate (CBFR) over a CPAP range of 0-20cm H2O. Dynamic response tests have proved that this CBFR mask can constrict the mask pressure swing by an order of two so as to offer better comfort for OSA patients.

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Ni, Yung-Lun, Yu-Lun Lo, Tsai-Yu Wang et Ting-Yu Lin. « Laryngeal obstruction in moderate and severe obstructive sleep apnea patients requested higher CPAP level during treatments ». Dans ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa4367.

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Şahin Duyar, S., et S. Fırat. « A new treatment option for treatment-emergent central apnea syndrome : a case series ». Dans Sleep and Breathing 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/23120541.sleepandbreathing-2021.7.

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Florou, E., A. Bonakis, K. Baou, H. Loutrari, A. Minaritzoglou et E. Vagiakis. « Treatment-emergent central sleep apnea ». Dans Sleep and Breathing 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/23120541.sleepandbreathing-2021.64.

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Zavrel, Erik A., et Matthew R. Ebben. « An Active Distal Limb Warming Device for Insomnia Treatment ». Dans 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3469.

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The defining characteristics of insomnia are widely recognized as difficulty falling asleep, difficulty staying asleep, and sleep that is non-restorative [1]. Insomnia is among the most common health complaints: about 10% of the adult population complains of a chronic insomnia problem [2]. With aging, increasingly disturbed sleep and less satisfaction with sleep quality are reported [3]. This common problem has wide ranging physiological, cognitive, and behavioral consequences including higher healthcare utilization [4–6]. Current major treatment options for insomnia (hypnotic medications and non-pharmacological behavioral interventions) suffer side effects and shortcomings. Thermoregulation plays a key role in promoting and maintaining sleep. At night, core body temperature (CBT) drops while distal skin temperature (DST) increases. It was previously believed that the nighttime drop in CBT was the most important promoter of sleep. However, recent research has shown that it is in fact the increase in DST (with net body heat loss owing to the large distal skin surface area) which is associated with an increase in sleepiness, whereas a decrease in DST (with resulting net body heat retention) is associated with a decrease in sleepiness [7]. The amount of distal vasodilation, as measured by the distal-proximal skin temperature gradient (DPG), is more predictive of sleep onset than subjective sleepiness ratings, CBT, or dim light melatonin onset. In fact, “the degree of dilation of blood vessels in the skin of the hands and feet, which increases heat loss at these extremities, is the best physiological predictor for the rapid onset of sleep” [8]. The link between distal skin warming and sleep propensity is further strengthened by the fact that warm water immersion of hands and feet has been found to decrease sleep onset latency (SOL) and pre-sleep warm baths have long been prescribed as an insomnia treatment. In a recent study, we used a multiple sleep latency test (MSLT) to perform multiple nap trials throughout the day, with the participants’ hands and feet immersed in warm water prior to each nap. We found that both mild and moderate warming of the hands and feet prior to a nap significantly reduced SOL compared to a baseline MSLT without warming [9]. We also previously conducted a trial of temperature biofeedback for insomnia treatment in which we demonstrated SOL reduction using muscle relaxation techniques to induce distal vasodilation, increase blood flow to the extremities, and modulate temperature of hands and feet [10]. Additionally, it has been shown that regardless of circadian variation throughout the day, finger temperature shows a rapid increase immediately before sleep onset [11]. Lastly, people with primary vascular dysregulation (a condition caused by abnormal vasoconstriction that results in cold hands and feet) exhibit significantly increased SOL and greater difficulty falling asleep following nocturnal arousal [12]. Thus, some presentations of insomnia may be secondary to distal vasodilation failure. The motivation for an active distal limb warming device as a treatment for insomnia is based on the established functional link between distal vasodilation and sleep induction [13]. Somewhat counterintuitively then, heating of hands and feet can induce distal vasodilation, promote net body heat loss, and facilitate sleep onset [14, 15].

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Pires, Gabriel Natan, Ksdy Maiara Moura Sousa, Thábita Maganete, Paula Villena Redondo et Renata Redondo Bonaldi. « SleepUp, a Digital Therapeutics Platform for Insomnia ». Dans XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.296.

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Background: Cognitive-Behavioral Therapy for Insomnia (CBTi) is the gold-standard treatment for chronic insomnia. Although effective, CBTi is not easily accessible due to a shortage of specialized professionals and high treatment costs. Online CBTi (CBTi-O) has been proposed as a more accessible and affordable treatment option. CBTi and CBTi-O are equally effective, and some apps have already been approved by regulatory agencies in USA (Somryst™) and UK (Sleepio™). Objetives: SleepUp is a digital therapeutics solution for insomnia, intended to provide evidence-based treatment in an easily accessible format. Methods: The treatment program is based on CBTi-O, composed by seven therapeutic modules (sleep hygiene, relaxation and meditation, psychoeducation, stimulus control, cognitive restructuring, sleep restriction and paradoxical intention). Users are monitored with a sleep log and validated questionnaires assessing insomnia symptoms, sleepiness, sleep quality and sleep hygiene. Additional therapy modules are included, encompassing mindfulness and other meditation techniques. For refractory cases or for those with comorbidities, remote appointments with medical doctors and psychologists specialized in sleep medicine are available. Results: SleepUp is an early-stage startup and its solutions for sleep and insomnia are being constantly developed and improved. The app is already available in Brazil and USA, both for Android™ and IOS™ devices. Preliminary results demonstrate that the treatment is effective, reducing insomnia symptoms in 28%, (n=1700), improving sleep hygiene scores in 32% (n=100) and increasing sleep efficiency in 16% (n=2500). Conclusion: SleepUp aims at providing a more accessible alternative to the treatment of insomnia, based on CBTI-O, an effective and safe therapeutic approach.

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Rapports d'organisations sur le sujet "Sleep treatments"

Germain, Anne. Neurobiology of Sleep and Sleep Treatments in PTSD (NOS-STIP). Fort Belvoir, VA : Defense Technical Information Center, octobre 2010. http://dx.doi.org/10.21236/ada537223.

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Steegman, Ralph, Anne-Marie Renkema, Herman Verbeek, Adriaan Schoeman, Anne Marie Kuijpers-Jagtman et Yijin Ren. Upper Airway Volumetric Changes on CBCT after Orthodontic Interventions : protocol for a systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, avril 2022. http://dx.doi.org/10.37766/inplasy2022.4.0017.

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Review question / Objective: Does the volume of the upper airway change after an orthodontic intervention? P: growing subjects, adults; I: orthodontic treatment, dentofacial orthopedics, extractions; C: untreated subjects and/or non-extractions; O: volumetric changes of the upper airway measured on CBCT scans. Condition being studied: The primary objective of orthodontic treatment is to establish optimal dental and/or skeletal relationship in harmony with the soft tissue morphology and functioning. In addition, un-impeding or facilitating airway growth and development is an important objective, especially in patients susceptible for airway obstruction or sleep apnea. It is therefore important to look into the effect of various orthodontic treatments on the 3D volumetric changes of the upper airway. Compared with the use of traditional 2D lateral cephalograms, CBCT scans provide the opportunity to perform measurements in more dimensions on the airway with demonstrated reliability. This systematic review therefore includes studies using CBCT scans for evaluation of the airway.

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Germain, Anne. Neurobiology of Sleep and Sleep Treatment Response in PTSD. Fort Belvoir, VA : Defense Technical Information Center, octobre 2009. http://dx.doi.org/10.21236/ada525916.

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O'Donnell, Christopher P. Sleep Resilience, Comorbid Anxiety, and Treatment in a Muring Model of PTSD. Fort Belvoir, VA : Defense Technical Information Center, décembre 2012. http://dx.doi.org/10.21236/ada580131.

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O'Donnell, Christopher P. Sleep Resilience, Comorbid Anxiety, and Treatment in a Murine Model of PTSD. Fort Belvoir, VA : Defense Technical Information Center, avril 2014. http://dx.doi.org/10.21236/ada603152.

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Liu, Zhen, Zhizhen Lv, Jiao Shi, Shuangwei Hong, Huazhi Huang et Lijiang Lv. Efficacy of traditional Chinese exercise in patients with chronic fatigue syndrome : a protocol for a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, septembre 2022. http://dx.doi.org/10.37766/inplasy2022.9.0022.

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Review question / Objective: Chronic fatigue syndrome (CFS) is a disease in which fatigue strikes or lasts for more than 6 months, accompanied by pain, sleep disturbance, anxiety, and depression. Moreover, it brings a heavy economic burden to society. Traditional Chinese exercises (TCEs) are a traditional Chinese medical treatment and have good efficacy on CFS, therefore, this systematic evaluation is to accurately evaluate the efficacy of TCEs on CFS. P: Patients with chronic fatigue syndrome. I: Traditional Chinese exercises. C: conventional exercise, acupuncture, physiotherapy, and other physical therapy methods. O: quality of life, fatigue, pain, sleep, anxiety, and depression. S: randomized controlled trials. Condition being studied: Chronic fatigue syndrome (CFS) is a disease in which fatigue strikes or lasts for more than 6 months, accompanied by pain, sleep disturbance, anxiety, and depression. Moreover, it brings a heavy economic burden to society. Traditional Chinese exercises (TCEs) are a traditional Chinese medical treatment and have good efficacy on CFS. Therefore, this systematic evaluation is to accurately evaluate the efficacy of TCEs on CFS, to provide an alternative therapy for clinical treatment of CFS.

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Drummond, Sean P. Role of Sleep Deprivation in Fear Conditioning and Extinction : Implications for Treatment of PTSD. Fort Belvoir, VA : Defense Technical Information Center, octobre 2014. http://dx.doi.org/10.21236/ada613608.

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Parthasarathy, Sairam, Stefano Guerra, Stuart F. Quan, Michael Grandner et Patricia L. Haynes. Does a Peer Support Program Improve Satisfaction With Treatment Among Patients With Obstructive Sleep Apnea ? Patient-Centered Outcomes Research Institute (PCORI), avril 2020. http://dx.doi.org/10.25302/04.2020.ihs.130602505.

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