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1

Langhorne, Peter, et Martin Dennis, dir. Stroke Units. Tavistock Square, UK : BMJ Books, 1998. http://dx.doi.org/10.1002/9780470760215.

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2

Fiedler, Christine, Martin Köhrmann et Rainer Kollmar, dir. Pflegewissen Stroke Unit. Berlin, Heidelberg : Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-29995-7.

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3

Fiedler, Christine, Martin Köhrmann et Rainer Kollmar, dir. Pflegewissen Stroke Unit. Berlin, Heidelberg : Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53625-4.

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4

Martin, Dennis, dir. Stroke units : An evidence based approach. London : BMJ Books, 1998.

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5

The Stone Court. Santa Barbara : ABC-CLIO, 2008.

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6

Hutchinson, Ron. Heat exchanger design for mass store hot water units. Leicester : De Montfort University, 1999.

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7

Massachusetts. Executive Office of Consumer Affairs and Business Regulation. Massachusetts food store item pricing law. Boston, Mass : The Office, 1990.

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8

McMillan, Dana. Pet store : A complete theme unit including learning centers. Carthage, IL : Teaching & Learning Co., 2000.

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9

McMillan, Dana. Pet store : A complete theme unit including learning centers. Carthage, IL : Teaching & Learning Co., 2000.

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10

dure, Opificio delle pietre, Galleria d'arte moderna (Florence, Italy) et Palazzo Pitti, dir. Dagli splendori di corte al lusso borghese : L'Opificio delle pietre dure nell'Italia unita. Livorno : Sillabe, 2011.

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11

McAlpine, Christine. Audit of resources required for a stroke unit in a district general hospital. [Edinburgh] : Scottish Office, 1994.

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12

Kalnins, Arturs. The characteristics of multi-unit ownership in franchising : Evidence from fast-food restaurants in Texas. Cambridge, MA : National Bureau of Economic Research, 1996.

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13

Canada. Health and Welfare. Federal-Provincial Advisory Committee on Institutional and Medical Services. Stroke program : Guidelines for establishing standards for units/services/programs in institutions : report of the Sub-Committee on Institutional Program Guidelines. Ottawa : Health and Welfare., 1986.

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14

King, Stephen. Ολα είναι δυνατά : 14 Εκοτεινές Ιστορίες. Athēna : Charlenik Hellas, 2009.

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15

King, Stephen. Everything's Eventual : 14 Dark Tales. New York, USA : Pocket Books, 2003.

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16

King, Stephen. Everything's Eventual : 14 Dark Tales. New York, USA : Pocket Books, 2003.

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17

King, Stephen. Everything's Eventual : 14 Dark Tales. New York, USA : Pocket Books, 2003.

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18

King, Stephen. Everything's Eventual : 14 Dark Tales. London, England : Hodder, 2007.

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19

Kalra, Lalit. Stroke units : research in practice. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199689644.003.0013.

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Key points• Stroke units are the cornerstone of quality stroke care.• The benefits of stroke unit care are supported by a very strong evidence base• In 2007 the National Stroke Strategy mandated that all stroke patients should have prompt access to stroke unit care.• Despite policy and guidelines, only 62% stroke patients were treated on specialist stroke units in 2010.• Patients spend long periods of inactivity on stroke units; multidisciplinary teams need to encourage rehabilitation activities outside therapy sessions.• Rehabilitation needs to be family- and carer-oriented to prepare patients for life after discharge.
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20

Stroke Unit. Pflaum, 2002.

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21

Meyer, Joachim, et Michael Laag. Stroke Unit. Huber, Bern, 2000.

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22

Bowker, Lesley K., James D. Price, Ku Shah et Sarah C. Smith. Stroke. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198738381.003.0008.

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This chapter provides information on definition and classification, predisposing factors, acute assessment, investigations, acute management, stroke units, thrombolysis, intra-arterial therapies, ongoing management, complications, longer-term issues, and transient ischaemic attack clinics.
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23

Leys, Didier, Charlotte Cordonnier et Valeria Caso. Stroke. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0067.

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Stroke is a major public health issue. Many are treatable in the acute stage, provided patients are admitted soon enough. The overall incidence of stroke in Western countries is approximately 2400 per year per million inhabitants, and 80% are due to cerebral ischaemia. The prevalence is approximately 12 000 per million inhabitants. Stroke is associated with increased long-term mortality, handicap, cognitive and behavioural impairments, recurrence, and an increased risk of other types of vascular events. It is of major interest to take the heterogeneity of stroke into account, because of differences in the acute management, secondary prevention, and outcomes, according to the subtype and cause of stroke. In all types of stroke, early epileptic seizures, delirium, increased intracranial pressure, and non-specific complications are frequent. In ischaemic strokes, specific complications, such as malignant infarcts, spontaneous haemorrhagic transformation, early recurrence, and a new ischaemic event in another vascular territory, are frequent. In haemorrhagic strokes, the major complication is the subsequent increased volume of bleeding. There is strong evidence that stroke patients should be treated in dedicated stroke units; each time 24 patients are treated in a stroke unit, instead of a conventional ward, one death and one dependence are prevented. This effect does not depend on age, severity, and the stroke subtype. For this reason, stroke unit care is the cornerstone of the treatment of stroke, aiming at the detection and management of life-threatening emergencies, stabilization of most physiological parameters, and prevention of early complications. In ischaemic strokes, besides this general management, specific therapies include intravenous recombinant tissue plasminogen activator, given as soon as possible and before 4.5 hours, otherwise aspirin 300 mg, immediately or after 24 hours in case of thrombolysis, and, in a few patients, decompressive surgery. In intracerebral haemorrhages, blood pressure lowering and haemostatic therapy, when needed, are the two targets, but surgery does not seem effective to reduce death and disability.
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24

Leys, Didier, Charlotte Cordonnier et Valeria Caso. Stroke. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0067_update_001.

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Stroke is a major public health issue. Many are treatable in the acute stage, provided patients are admitted soon enough. The overall incidence of stroke in Western countries is approximately 2400 per year per million inhabitants, and 80% are due to cerebral ischaemia. The prevalence is approximately 12 000 per million inhabitants. Stroke is associated with increased long-term mortality, handicap, cognitive and behavioural impairments, recurrence, and an increased risk of other types of vascular events. It is of major interest to take the heterogeneity of stroke into account, because of differences in the acute management, secondary prevention, and outcomes, according to the subtype and cause of stroke. In all types of stroke, early epileptic seizures, delirium, increased intracranial pressure, and non-specific complications are frequent. In ischaemic strokes, specific complications, such as malignant infarcts, spontaneous haemorrhagic transformation, early recurrence, and a new ischaemic event in another vascular territory, are frequent. In haemorrhagic strokes, the major complication is the subsequent increased volume of bleeding. There is strong evidence that stroke patients should be treated in dedicated stroke units; each time 24 patients are treated in a stroke unit, instead of a conventional ward, one death and one dependence are prevented. This effect does not depend on age, severity, and the stroke subtype. For this reason, stroke unit care is the cornerstone of the treatment of stroke, aiming at the detection and management of life-threatening emergencies, stabilization of most physiological parameters, and prevention of early complications. In ischaemic strokes, besides this general management, specific therapies include intravenous recombinant tissue plasminogen activator, given as soon as possible and before 4.5 hours, otherwise aspirin 300 mg, immediately or after 24 hours in case of thrombolysis, and, in a few patients, decompressive surgery. In intracerebral haemorrhages, blood pressure lowering and haemostatic therapy, when needed, are the two targets, but surgery does not seem effective to reduce death and disability.
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25

Leys, Didier, Charlotte Cordonnier et Valeria Caso. Stroke. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0067_update_002.

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Stroke is a major public health issue. Many are treatable in the acute stage, provided patients are admitted soon enough. The overall incidence of stroke in Western countries is approximately 2400 per year per million inhabitants, and 80% are due to cerebral ischaemia. The prevalence is approximately 12 000 per million inhabitants. Stroke is associated with increased long-term mortality, handicap, cognitive and behavioural impairments, recurrence, and an increased risk of other types of vascular events. It is of major interest to take the heterogeneity of stroke into account, because of differences in the acute management, secondary prevention, and outcomes, according to the subtype and cause of stroke. In all types of stroke, early epileptic seizures, delirium, increased intracranial pressure, and non-specific complications are frequent. In ischaemic strokes, specific complications, such as malignant infarcts, spontaneous haemorrhagic transformation, early recurrence, and a new ischaemic event in another vascular territory, are frequent. In haemorrhagic strokes, the major complication is the subsequent increased volume of bleeding. There is strong evidence that stroke patients should be treated in dedicated stroke units; each time 24 patients are treated in a stroke unit, instead of a conventional ward, one death and one dependence are prevented. This effect does not depend on age, severity, and the stroke subtype. For this reason, stroke unit care is the cornerstone of the treatment of stroke, aiming at the detection and management of life-threatening emergencies, stabilization of most physiological parameters, and prevention of early complications. In ischaemic strokes, besides this general management, specific therapies include intravenous recombinant tissue plasminogen activator, given as soon as possible and before 4.5 hours, mechanical thrombectomy in case of proximal occlusion (middle cerebral artery, intracranial internal carotid artery, basilar artery), on top of thrombolysis in the absence of contraindication or alone otherwise, aspirin 300 mg, immediately or after 24 hours in case of thrombolysis, and, in a few patients, decompressive surgery. In intracerebral haemorrhages, blood pressure lowering and haemostatic therapy, when needed, are the two targets, while surgery does not seem effective to reduce death and disability.
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26

Dennis, Martin. Stroke Units : An Evidence Based Approach. BMJ Publishing Group, 1998.

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27

Dennis, Martin, et Peter Langhorne. Stroke Units : An Evidence Based Approach. Wiley & Sons, Incorporated, John, 2008.

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28

Scotland. Health Department. Coronary Heart Disease/Stroke Task Force., dir. Coronary Heart Disease/Stroke Task Force report. [Edinburgh] : [Scottish Executive], 2001.

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29

Warlow, Charles, et Jan van Gijn. Stroke. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199658602.003.0005.

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This chapter includes ten influential papers in the development of ideas about the causes and management of stroke. These are papers that have changed medical thinking or practice, or both simultaneously, and they cover the following topics: the carotid artery; angiography; carotid endarterectomy; embolism from the heart and atrial fibrillation; ruptured intracranial aneurysms recognized during life; intracranial venous thrombosis; thrombolysis in acute ischaemic stroke; and transient ischaemic attacks. The problematic issue of how to measure the severity of disease is addressed; and the history and development of specialist stroke units is also covered.
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30

Markus, Hugh, Anthony Pereira et Geoffrey Cloud. Organization of stroke services. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198737889.003.0016.

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The chapter on organization of stroke services discusses the evidence for stroke unit care and defines what this means within hospitals. The chapter sets out the patient pathway starting with pre-hospital care the assessment using the Face Arm Speech Test (FAST). It then moves to the acute hospital care emergency department (Recognition of Stroke in the Emergency Room, ROSIER) and consideration of thrombolysis and admission to an acute stroke unit. Rehabilitation and transition of care into the community including early support discharge bookends the chapter. Staffing levels are discussed as is the relationship between stroke unit nursing levels and mortality.
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31

Lovelady, Janet. Stone Soup Literature Mini-Unit (Workbook). Mari, 1989.

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32

Markus, Hugh, Anthony Pereira et Geoffrey Cloud. Acute stroke treatment. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198737889.003.0009.

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In this chapter the use of thrombolysis and the more recent application of thrombectomy in acute ischaemic stroke are covered. Organized stroke unit care has a major impact on both reducing mortality and improving outcome, and the chapter describes the evidence for this. It also covers other components of supportive acute stroke care, including the importance of instituting measures to avoid complications and to prevent early recurrent stroke.
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33

Canada. Health Services and Promotion Branch. et Federal-Provincial Advisory Committee on Institutional and Medical Services (Canada). Subcommittee on Institutional Program Guidelines, dir. Stroke program : Guidelines for establishing standards for units/services/programs in institutions. Ottawa : Health Services Directorate, Health Services and Promotion Branch, 1986.

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34

Fiedler, Christine, Martin Köhrmann et Rainer Kollmar. Pflegewissen Stroke Unit : Für die Fortbildung und die Praxis. Springer, 2017.

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35

(Editor), Judy Mitchell, et Gary Mohrman (Illustrator), dir. Grocery Store : A Complete Theme Unit Including Learning Centers. Teaching & Learning Company, 1999.

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36

Pflegewissen Stroke Unit Fur Die Fortbildung Und Die Praxis. Springer, 2012.

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37

Markus, Hugh, Anthony Pereira et Geoffrey Cloud. Stroke Medicine (Oxford Specialist Handbooks in Neurology). Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198737889.001.0001.

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Recent years have seen a revolution in the profile of stroke. Often thought of as an untreatable disease we now realize that not only can many strokes be prevented, but acute treatment can have a major impact on outcome. There has been great recent interest in thrombolysis and thrombectomy but other aspects of stroke care including organized stroke unit care, and effective secondary prevention and rehabilitation also have a major impact on outcome. Clinicians looking after stroke patients need rapid access to up-to-date practical information on how to look after stroke patients. This handbook of Stroke Medicine is aimed to provide a ready source of information for both stroke trainees and consultants. It covers diagnosis and investigation of the stroke patient, as well as treatment ranging from primary and secondary prevention, to acute care and rehabilitation. It also covers rarer causes of stroke and the increasing important area of vascular cognitive impairment. It is written to cover the syllabus of the UK stroke specialist training programme and other similar programmes worldwide.
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38

Renstrom, Peter. The Stone Court : Justices, Rulings, and Legacy (ABC-Clio Supreme Court Handbooks). ABC-CLIO, 2001.

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39

Mackinnon, Tim, et Steve Freeman. No Stone Unturned : A Unit Testing Cookbook for Extreme Programmers. Pearson Education, Limited, 2007.

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40

Iwnicki, Anna Amelia. Models used to shape information-giving by stroke unit staff. 1995.

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41

Mayor, Diana, et Michael Tymianski. Neuroprotection for Acute Ischemic Stroke. Sous la direction de David L. Reich, Stephan Mayer et Suzan Uysal. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190280253.003.0010.

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Acute ischemic stroke (AIS) is the leading cause of acquired neurological disability worldwide. AIS most commonly occurs when a cerebral artery is occluded, leading to irreversible brain injury and neurologic disability. Acute supportive physiological interventions and close monitoring on a stroke unit are beneficial to optimize overall recovery and functional outcome. Phamacological treatment options are limited though as the only FDA-approved therapy for AIS is the thrombolytic agent intravenous recombinant tissue plasminogen activator (Alteplase, rtPA), which improves functional outcome in therapeutic time windows ranging up to 3–4.5 hours. Several clinical trials assessing the efficacy of endovascular therapy have shown a benefit in carefully selected patients with a documented large vessel occlusion (LVO), and subsequently are becoming part of the standard practice in this AIS subset. Clinical trials using various imaging paradigms to enhance patient selection for thrombolytic therapy, endovascular therapy and neuroprotection therapies are all progressing.
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42

Stroke : An Epidemiological Overview (Central Health Monitoring Unit Epidemiological Overview Seri). Bernan Press, 1994.

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43

Union on the Kings Highway (The Campbell Stone Heritage of Unity Series). College Pr Pub Co, 1987.

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44

Meyer, Michel. Rhetoric and argumentation : the unity of the field. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780199691821.003.0003.

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Rhetoric has always been torn between the rhetoric of figures and the rhetoric of conflicts or arguments, as if rhetoric were exclusively one or the other. This is a false dilemma. Both types of rhetoric hinge on the same structure. A common formula is provided in Chapter 3 which unifies rhetoric stricto sensu and rhetoric as argumentation as two distinct but related strategies adopted according to the level of problematicity of the questions at stake, thereby giving unity to the field called “Rhetoric.” Highly problematic questions require arguments to justify their answers; non-divisive ones can be treated rhetorically through their answers as if they were self-evident. Another classic problem is how to understand the difference between logic and rhetoric. The difference between the two is due to the presence of questions explicitly answered in the premises in logic and only suggested (or remaining indeterminate) in rhetoric.
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45

Kirch, Patrick V. The Prehistory of Hawai‘i. Sous la direction de Ethan E. Cochrane et Terry L. Hunt. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199925070.013.027.

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The Hawaiian Islands are the most isolated inhabited archipelago in the world. Initially colonized around A.D. 1000, the environmental gradients of rainfall and island-age have influenced subsequent cultural variation and differentiation in the islands. Settlements are typically dispersed hamlets and integrated within agricultural facilities such as irrigated pondfields and dryland field systems. Populations were politically organized in idealized pie-shaped units or ahupua`a that typically encompass a cross-section of island resources. Material culture , including fishhooks, stone tools, and religious temples, is broadly similar within these units, but there is also much evidence for elite control of specialized production in some areas. The Hawaiian Islands are the archetypal chiefdom society, although based on changes in demography, monumental architecture (heiau) and royal centers, intensive agriculture, and divine kingship, the population had likely crossed the threshold of sociopolitical complexity to that of an archaic state prior to the arrival of Europeans in 1778.
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46

Hoffman, Marion B. Harry Potter and the Sorcerer's Stone : A Unit Plan (Litplans on CD). Teachers Pet Pubns Inc, 2001.

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47

Shein, Steven L., et Robert S. B. Clark. Neurocritical Care. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199918027.003.0009.

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Brain injury is the most common proximate cause of death in pediatric intensive care units. For children who survive critical illness, long-standing brain damage and residual brain dysfunction can affect quality of life significantly. Therefore, minimizing neurological injury to improve patient outcomes is a priority of neurocritical care. This may be accomplished by implementing specific targeted therapies, avoiding pathophysiological conditions that exacerbate neurological injury, and using a multidisciplinary team that focuses on contemporary care of children with neurological injury and disease. This chapter reviews pertinent anatomy and physiology; general principles of pediatric neurocritical care; and specifics for caring for children with traumatic brain injury, hypoxic–ischemic encephalopathy, status epilepticus, meningitis/encephalitis, stroke, and acute hydrocephalus.
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48

Parker, Philip M. The 2007-2012 World Outlook for School Single-Pupil Units Excluding Library Furniture and Furniture Made from Stone and Concrete. ICON Group International, Inc., 2006.

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49

The 2006-2011 World Outlook for School Single-Pupil Units Excluding Library Furniture and Furniture Made from Stone and Concrete. Icon Group International, Inc., 2005.

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50

Marx, Gernot, et Michael Fries. Acute illness in the postoperative period. Sous la direction de Neil Soni et Jonathan G. Hardman. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0089.

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As more complex and risky surgical procedures are carried out in industrialized countries, anaesthetists are confronted with higher incidences of acute life-threatening conditions during the perioperative period. This is especially true for older patients with concomitant morbidities. Sepsis, cardiovascular complications including myocardial infarction, pulmonary embolism, and stroke, as well as massive bleeding are among the most severe complications that may arise during any time in the postoperative period starting as early as in the post-anaesthesia care unit. Early identification along with rapid stabilization of vital signs are key to improving outcomes in these patients.
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