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1

LIU, XIAOQIU. "Managing Cardiovascular Risk in Hypertension: Methodological Issues in Blood Pressure Data Analysis." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2017. http://hdl.handle.net/10281/154475.

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Hypertension remains in 2017 a leading cause of mortality and disability worldwide. A number of issues related to the determinants of cardiovascular risk in hypertensive patients and to the strategies for better hypertension control are still pending. In such a context, aims of my research program were: 1. To investigate the contribution of blood pressure variability to the risk of cardiovascular mortality in hypertensive patients. In this setting, different methods for assessing blood pressure variability and different models exploring the link between blood pressure variability and outcome
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TASSISTRO, ELENA. "Adverse events in survival data: from clinical questions to methods for statistical analysis." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2022. http://hdl.handle.net/10281/365520.

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Nello studio di un nuovo trattamento con un tempo di sopravvivenza come outcome, l’insuccesso può essere definito in modo da includere un evento avverso serio (AE) tra gli endpoint tipicamente considerati, come ad esempio ricaduta o progressione. Questi eventi si comportano come rischi competitivi, dove l’occorrenza di una ricaduta come primo evento e il conseguente cambio di trattamento escludono la possibilità di osservare AE legati al trattamento stesso. L’analisi degli AE può essere affrontata mediante due diversi approcci: 1. descrizione dell’occorrenza osservata di AE come primo evento:
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3

Bruno, Rexanne Marie. "Statistical Analysis of Survival Data." UNF Digital Commons, 1994. http://digitalcommons.unf.edu/etd/150.

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The terminology and ideas involved in the statistical analysis of survival data are explained including the survival function, the probability density function, the hazard function, censored observations, parametric and nonparametric estimations of these functions, the product limit estimation of the survival function, and the proportional hazards estimation of the hazard function with explanatory variables. In Appendix A these ideas are applied to the actual analysis of the survival data for 54 cervical cancer patients.
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4

Fontenelle, OtÃvio Fernandes. "Survival Analysis; Micro and Small Enterprises; Modeling Survival Data, Data Characterization Survival; parametric Estimator KAPLAN-MEIER." Universidade Federal do CearÃ, 2009. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=4173.

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nÃo hÃ<br>The main objective of this research is to explore economics issues that may induce impact on lifetime of small businesses during 2002 to 2006. The group of enterprises studied was selected from database of taxpayers recorded at fiscal authority of State of CearÃ. To do that, the methodology was focused on a branch of statistics which deals with survival analysis, called duration analysis or duration modeling in economics. It was applied non-linear model whose non-parametric estimator chosen was KAPLAN-MEIER. Through that methodology, it was developed sceneries based on the following
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5

葉英傑 and Ying-Kit David Ip. "Analysis of clustered grouped survival data." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31226127.

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Ip, Ying-Kit David. "Analysis of clustered grouped survival data /." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B2353011x.

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7

Lee, Yau-wing. "Modelling multivariate survival data using semiparametric models." Click to view the E-thesis via HKUTO, 2000. http://sunzi.lib.hku.hk/hkuto/record/B4257528X.

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8

Nhogue, Wabo Blanche Nadege. "Hedge Funds and Survival Analysis." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/26257.

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Using data from Hedge Fund Research, Inc. (HFR), this study adapts and expands on existing methods in survival analysis in an attempt to investigate whether hedge funds mortality can be predicted on the basis of certain hedge funds characteristics. The main idea is to determine the characteristics which contribute the most to the survival and failure probabilities of hedge funds and interpret them. We establish hazard models with time-independent covariates, as well as time-varying covariates to interpret the selected hedge funds characteristics. Our results show that size, age, performance, s
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9

Frévent, Camille. "Contribution to spatial statistics for high-dimensional and survival data." Electronic Thesis or Diss., Université de Lille (2022-....), 2022. http://www.theses.fr/2022ULILS032.

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Dans ce mémoire de thèse nous nous intéressons aux méthodes d'apprentissage statistique pour données spatiales en grande dimension et données de survie. L'objectif est de développer des méthodes de détection de clusters non supervisées avec des statistiques de scan spatiales, à la fois dans le cadre de l'analyse de données fonctionnelles, mais aussi pour l'analyse de données de survie. Nous considérons tout d'abord des données fonctionnelles univariées ou multivariées mesurées spatialement dans une région géographique. Nous proposons des statistiques de scan paramétriques et non paramétriques
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10

Kulich, Michal. "Additive hazards regression with incomplete covariate data /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/9562.

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梁翠蓮 and Tsui-lin Leung. "Proportional odds model for survival data." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B42575011.

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12

Leung, Tsui-lin. "Proportional odds model for survival data." Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/hkuto/record/B42575011.

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13

林國輝 and Kwok-fai Lam. "Topics in survival analysis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1994. http://hub.hku.hk/bib/B30408994.

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Lam, Kwok-fai. "Topics in survival analysis /." Hong Kong : University of Hong Kong, 1994. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13829919.

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15

李友榮 and Yau-wing Lee. "Modelling multivariate survival data using semiparametric models." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B4257528X.

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16

Zhou, Feifei, and 周飞飞. "Cure models for univariate and multivariate survival data." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B45700977.

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17

Liu, Fei, and 劉飛. "Statistical inference for banding data." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41508701.

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Liu, Fei. "Statistical inference for banding data." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41508701.

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19

Oller, Piqué Ramon. "Survival analysis issues with interval-censored data." Doctoral thesis, Universitat Politècnica de Catalunya, 2006. http://hdl.handle.net/10803/6520.

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L'anàlisi de la supervivència s'utilitza en diversos àmbits per tal d'analitzar dades que mesuren el temps transcorregut entre dos successos. També s'anomena anàlisi de la història dels esdeveniments, anàlisi de temps de vida, anàlisi de fiabilitat o anàlisi del temps fins a l'esdeveniment. Una de les dificultats que té aquesta àrea de l'estadística és la presència de dades censurades. El temps de vida d'un individu és censurat quan només és possible mesurar-lo de manera parcial o inexacta. Hi ha diverses circumstàncies que donen lloc a diversos tipus de censura. La censura en un interval fa r
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20

Long, Yongxian, and 龙泳先. "Semiparametric analysis of interval censored survival data." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45541152.

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21

Aparicio, Vázquez Ignacio. "Venn Prediction for Survival Analysis : Experimenting with Survival Data and Venn Predictors." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-278823.

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The goal of this work is to expand the knowledge on the field of Venn Prediction employed with Survival Data. Standard Venn Predictors have been used with Random Forests and binary classification tasks. However, they have not been utilised to predict events with Survival Data nor in combination with Random Survival Forests. With the help of a Data Transformation, the survival task is transformed into several binary classification tasks. One key aspect of Venn Prediction are the categories. The standard number of categories is two, one for each class to predict. In this work, the usage of ten c
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22

Hirst, William Mark. "Outcome measurement error in survival analysis." Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366352.

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23

Liu, Yang. "Transformation models for survival data analysis and applications." Tallahassee, Florida : Florida State University, 2009. http://etd.lib.fsu.edu/theses/available/etd-03242009-145017/.

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Thesis (Ph. D.)--Florida State University, 2009.<br>Advisor: Xu-Feng Niu, Florida State University, College of Arts and Sciences, Dept. of Statistics. Title and description from dissertation home page (viewed on Nov. 18, 2009). Document formatted into pages; contains x, 97 pages. Includes bibliographical references.
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24

Wang, Huan. "Survival analysis for censored data under referral bias." Thesis, University of Brighton, 2014. https://research.brighton.ac.uk/en/studentTheses/5b39ddc3-1c64-4dd2-8182-a4014c6b97b6.

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This work arises from a hepatitis C cohort study and focuses on estimating the effects of covariates on progression to cirrhosis. In hepatitis C cohort studies, patients may be recruited to the cohort with referral bias because clinically the patients with more rapid disease progression are preferentially referred to liver clinics. This referral bias can lead to significantly biased estimates of the effects of covariates on progression to cirrhosis.
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25

Lim, Hee-Jeong. "Statistical analysis of interval-censored and truncated survival data /." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3025635.

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26

Zhang, Yue. "Bayesian Cox Models for Interval-Censored Survival Data." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1479476510362603.

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27

Pecková, Monika. "Efficiency based adaptive tests for censored survival data /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/9599.

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28

Nwi-Mozu, Isaac. "Robustness of Semi-Parametric Survival Model: Simulation Studies and Application to Clinical Data." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etd/3618.

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An efficient way of analyzing survival clinical data such as cancer data is a great concern to health experts. In this study, we investigate and propose an efficient way of handling survival clinical data. Simulation studies were conducted to compare performances of various forms of survival model techniques using an R package ``survsim". Models performance was conducted with varying sample sizes as small ($n5000$). For small and mild samples, the performance of the semi-parametric outperform or approximate the performance of the parametric model. However, for large samples, the parametric mod
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29

Nieto-Barajas, Luis E. "Bayesian nonparametric survival analysis via Markov processes." Thesis, University of Bath, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343767.

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30

Martinenko, Evgeny. "Functional Data Analysis and its application to cancer data." Doctoral diss., University of Central Florida, 2014. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/6323.

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The objective of the current work is to develop novel procedures for the analysis of functional data and apply them for investigation of gender disparity in survival of lung cancer patients. In particular, we use the time-dependent Cox proportional hazards model where the clinical information is incorporated via time-independent covariates, and the current age is modeled using its expansion over wavelet basis functions. We developed computer algorithms and applied them to the data set which is derived from Florida Cancer Data depository data set (all personal information which allows to identi
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31

Boyd, Katherine. "Non-ignorable missing covariate data in parametric survival analysis." Thesis, University of Warwick, 2007. http://wrap.warwick.ac.uk/55751/.

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Within any epidemiological study missing data is almost inevitable. This missing data is often ignored; however, unless we can assume quite restrictive mechanisms, this will lead to biased estimates. Our motivation are data collected to study the long-term effect of severity of disability upon survival in children with cerebral palsy (henceforth CP). The analysis of such an old data set brings to light statistical difficulties. The main issue in this data is the amount of missing covariate data. We raise concerns about the mechanism causing data to be missing. We present a flexible class of jo
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32

Rajeev, Deepthi. "Separate and Joint Analysis of Longitudinal and Survival Data." Diss., CLICK HERE for online access, 2007. http://contentdm.lib.byu.edu/ETD/image/etd1775.pdf.

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33

Macis, Ambra. "Statistical Models and Machine Learning for Survival Data Analysis." Doctoral thesis, Università degli studi di Brescia, 2023. https://hdl.handle.net/11379/568945.

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L'argomento principale di questa tesi è l'analisi della sopravvivenza, un insieme di metodi utilizzati negli studi longitudinali in cui l'interesse non è solo nel verificarsi (o meno) di un particolare evento, ma anche nel tempo necessario per osservarlo. Negli anni sono stati inizialmente proposti dei modelli statistici e, in seguito, sono stati introdotti anche metodi di machine learning per affrontare studi di analisi di sopravvivenza. La prima parte del lavoro fornisce un'introduzione ai concetti di base dell'analisi di sopravvivenza e un'ampia rassegna della letteratura esistente. Nello
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34

Che, Huiwen. "Cutoff sample size estimation for survival data: a simulation study." Thesis, Uppsala universitet, Statistiska institutionen, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-234982.

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This thesis demonstrates the possible cutoff sample size point that balances goodness of es-timation and study expenditure by a practical cancer case. As it is crucial to determine the sample size in designing an experiment, researchers attempt to find the suitable sample size that achieves desired power and budget efficiency at the same time. The thesis shows how simulation can be used for sample size and precision calculations with survival data. The pre-sentation concentrates on the simulation involved in carrying out the estimates and precision calculations. The Kaplan-Meier estimator and
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35

Louw, Elizabeth Magrietha. "Fitting of survival functions for grouped data on insurance policies." Pretoria : [s.n.], 2005. http://upetd.up.ac.za/thesis/available/etd-11282005-123928.

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36

Cai, Jianwen. "Generalized estimating equations for censored multivariate failure time data /." Thesis, Connect to this title online; UW restricted, 1992. http://hdl.handle.net/1773/9581.

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Wong, Kin-yau, and 黃堅祐. "Analysis of interval-censored failure time data with long-term survivors." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48199473.

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Failure time data analysis, or survival analysis, is involved in various research fields, such as medicine and public health. One basic assumption in standard survival analysis is that every individual in the study population will eventually experience the event of interest. However, this assumption is usually violated in practice, for example when the variable of interest is the time to relapse of a curable disease resulting in the existence of long-term survivors. Also, presence of unobservable risk factors in the group of susceptible individuals may introduce heterogeneity to the po
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Louw, Elizabeth Magrietha. "Fitting of survival functions for grouped data on insurance policies." Diss., University of Pretoria, 2002. http://hdl.handle.net/2263/29891.

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The aim of the research is the statistical modelling of parametric survival distributions of grouped survival data of long- and shortterm policies in the insurance industry, by means of a method of maximum likelihood estimation subject to constraints. This methodology leads to explicit expressions for the estimates of the parameters, as well as for approximated variances and covariances of the estimates, which gives exact maximum likelihood estimates of the parameters. This makes direct extension to more complex designs feasible. The statistical modelling offers parametric models for survival
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39

Boudreau, Christian. "Duration Data Analysis in Longitudinal Survey." Thesis, University of Waterloo, 2003. http://hdl.handle.net/10012/1043.

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Considerable amounts of event history data are collected through longitudinal surveys. These surveys have many particularities or features that are the results of the dynamic nature of the population under study and of the fact that data collected through longitudinal surveys involve the use of complex survey designs, with clustering and stratification. These particularities include: attrition, seam-effect, censoring, left-truncation and complications in the variance estimation due to the use of complex survey designs. This thesis focuses on the last two points. Statistical methods
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40

Shinohara, Russell. "Estimation of survival of left truncated and right censored data under increasing hazard." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=100210.

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When subjects are recruited through a cross-sectional survey they have already experienced the initiation of the event of interest, say the onset of a disease. This method of recruitment results in the fact that subjects with longer duration of the disease have a higher chance of being selected. It follows that censoring in such a case is not non-informative. The application of standard techniques for right-censored data thus introduces a bias to the analysis; this is referred to as length-bias. This paper examines the case where the subjects are assumed to enter the study at a uniform rate, a
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Akcin, Haci Mustafa. "Direct adjustment method on Aalen's additive hazards model for competing risks data." unrestricted, 2008. http://etd.gsu.edu/theses/available/etd-04182008-095207/.

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Thesis (M.S.)--Georgia State University, 2008.<br>Title from file title page. Xu Zhang, committee chair; Yichuan Zhao, Jiawei Liu, Yu-Sheng Hsu, committee members. Electronic text (51 p.) : digital, PDF file. Description based on contents viewed July 15, 2008. Includes bibliographical references (p. 50-51).
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Meddis, Alessandra. "Inference and validation of prognostic marker for correlated survival data with application to cancer." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASR005.

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Les données de survie en grappes sont souvent recueillies dans le cadre de la recherche médicale. Elles sont caractérisées par des corrélations entre des observations appartenant à un même groupe. Ici, nous discutons des extensions a des données en grappes dans différents contextes : évaluation de la performance d'un biomarqueur candidat, et l’estimation de l'effet du traitement dans une méta-analyse sur données individuels (IPD) avec risques concurrents. La première a été motivée par l'étude IMENEO, une méta-analyse où l'intérêt portait sur la validité pronostique des cellules tumorales circu
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López, Segovia Lucas. "Survival data analysis with heavy-censoring and long-term survivors." Doctoral thesis, Universitat Politècnica de Catalunya, 2014. http://hdl.handle.net/10803/276170.

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The research developed in this thesis has been motivated by two datasets, which are introduced in Chapter 2, one concerning the mortality of calves from birth to weaning while the other refers to survival of patients diagnosed with melanoma. In both cases the percentage of censoring is high, it is very likely to have immune individuals and proper analysis accounting for the possibility of a not negligible proportion of cured individuals has to be performed. Cure models are introduced in Chapter 3 together with the available software to perform the analysis, such as SAS, R and STATA, among othe
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Branson, Michael Robert. "The analysis of survival data in which patients switch treatment." Thesis, University of Reading, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394239.

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DIAS, Cícero Rafael Barros. "New continuous distributions applied to lifetime data and survival analysis." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/17307.

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Submitted by Isaac Francisco de Souza Dias (isaac.souzadias@ufpe.br) on 2016-07-08T19:03:53Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Tese_CiceroDias_VersaoCD.pdf: 1665746 bytes, checksum: bf5520194ce2f18a505403954f133c62 (MD5)<br>Made available in DSpace on 2016-07-08T19:03:53Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Tese_CiceroDias_VersaoCD.pdf: 1665746 bytes, checksum: bf5520194ce2f18a505403954f133c62 (MD5) Previous issue date: 2016-02-23<br>Statistical analysis of lif
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Kelly, Jodie. "Topics in the statistical analysis of positive and survival data." Thesis, Queensland University of Technology, 1998.

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47

Cheung, Tak-lun Alan, and 張德麟. "Modelling multivariate interval-censored and left-truncated survival data using proportional hazards model." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B29536637.

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48

Nan, Bin. "Information bounds and efficient estimates for two-phase designs with lifetime data /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/9587.

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Li, Qiuju. "Statistical inference for joint modelling of longitudinal and survival data." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/statistical-inference-for-joint-modelling-of-longitudinal-and-survival-data(65e644f3-d26f-47c0-bbe1-a51d01ddc1b9).html.

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In longitudinal studies, data collected within a subject or cluster are somewhat correlated by their very nature and special cares are needed to account for such correlation in the analysis of data. Under the framework of longitudinal studies, three topics are being discussed in this thesis. In chapter 2, the joint modelling of multivariate longitudinal process consisting of different types of outcomes are discussed. In the large cohort study of UK north Stafforshire osteoarthritis project, longitudinal trivariate outcomes of continuous, binary and ordinary data are observed at baseline, year
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Mason, Tracey. "Application of survival methods for the analysis of adverse event data." Thesis, Keele University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267646.

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The concept of collecting Adverse Events (AEs) arose with the advent of the Thalidomide incident. Prior to this the development and marketing of drugs was not regulated in any way. It was the teterogenic effects which raised people's awareness of the damage prescription drugs could cause. This thesis will begin by describing the background to the foundation of the Committee for the Safety of Medicines (CSM) and how AEs are collected today. This thesis will investigate survival analysis, discriminant analysis and logistic regression to identify prognostic indicators. These indicators will be de
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