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Thèses sur le sujet « Susceptibilité au stress »

Auteur : Grafiati

Publié le 20 juillet 2024

Mis à jour le 31 juillet 2025

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1

Merlot, Elodie. "Modulation de la production de cytokines par l'environnement social et susceptibilité aux infections." Paris, Institut national d'agronomie de Paris Grignon, 2003. https://pastel.archives-ouvertes.fr/pastel-00000790.

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L'environnement social contribue au développement et à l'expression de maladies. En effet, dans les espèces sociales, la susceptibilité aux infections dépend de la position sociale mais les bases endocriniennes et immunitaires de ces différences au sein du groupe sont ignorées. De plus, une modification de la structure sociale engendre un stress important dont les conséquences immunitaires sont encore sujettes à controverse. Ce travail de thèse a pour objectifs (1) de décrire l'influence du statut social sur le fonctionnement des systèmes endocrinien et immunitaire, (2) de préciser les effets

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2

Blein, Sophie. "Étude de la variabilité du génome mitochondrial comme facteur de susceptibilité au cancer du sein." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10240/document.

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Une large part de la composante génétique du risque de cancer du sein est encore inexpliquée. J'ai ainsi étudié dans quelle mesure les variants observés sur le génome mitochondrial pourraient en partie expliquer ce risque. En effet la mitochondrie, en tant que source d'énergie cellulaire, est un organite impliqué dans la synthèse des espèces oxygénées réactives ou radicaux libres, éléments contribuant à l'instabilité génomique et au développement tumoral. Un premier axe de recherche m'a conduit à étudier une interaction potentielle entre des variants du génome mitochondrial et du génome nucléa

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3

Rakotobé, Malalaniaina. "Bases neuro-développementales de la susceptibilité à l’anxiété : apports de l’étude du système habénulo-interpédonculaire." Electronic Thesis or Diss., Université Côte d'Azur, 2021. http://www.theses.fr/2021COAZ6002.

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Les circuits de récompense du cerveau sont des réseaux neuronaux qui modulent positivement ou négativement la motivation à agir. Ils sont essentiels à la survie en sélectionnant les comportements adaptés à la situation, comme fuir les dangers ou rechercher de la nourriture. Leurs dysfonctionnements peuvent entraîner des troubles de l’humeur et des addictions. Bien que ces troubles psychiatriques se manifestent chez l’adulte, selon l’hypothèse neuro-développementale ils peuvent avoir une origine plus précoce. En effet, il existe des périodes particulières du développement appelées périodes crit

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4

Moulin, Sophie. "Rôle de l'hypoxia-inducible factor-1 dans la susceptibilité myocardique à l'ischémie-reperfusion induite par l'hypoxie intermittente." Thesis, Université Grenoble Alpes (ComUE), 2018. http://www.theses.fr/2018GREAV034/document.

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Le syndrome d’apnées obstructives du sommeil (SAOS) est un problème de santé publique majeur qui est considéré comme un facteur indépendant de risque de survenue d’un infarctus du myocarde (IM). Les altérations cardiovasculaires associées au SAOS sont principalement dues à l’hypoxie intermittente (HI) chronique. En particulier, l’HI induit l’activation du facteur de transcription hypoxia-inducible factor-1 (HIF-1), susceptible d’être impliqué dans la vulnérabilité accrue du myocarde à l’ischémie-reperfusion. L’objectif de cette thèse était d’étudier le rôle de HIF-1 dans les mécanismes induits

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5

Le, guernic Antoine. "Effets sublétaux d'une contamination métallique liée à des rejets miniers uranifères sur l'épinoche à trois épines (Gasterosteus aculeatus L.). Implication dans la susceptibilité envers un stress biologique." Thesis, Reims, 2015. http://www.theses.fr/2015REIMS027.

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L’extraction de l’uranium a eu pour conséquence une remobilisation de cet actinide au niveau des écosystèmes avoisinants les mines. L’utilisation de sels métalliques lors de la réhabilitation des sites miniers et la présence naturelle de métaux ont accentué les niveaux de la contamination métallique dans les hydrosystèmes soumis aux rejets miniers uranifères.Des expériences in situ ont été conduites au niveau de deux anciens sites miniers uranifères français. L’encagement de l’épinoche à trois épines a été employé pour connaître les effets sublétaux de ce mélange métallique, ainsi que sur la s

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6

Pujol, Marine. "Variabilité comportementale en réponse au stress social : influence du variant allélique VGLUT3-p.T8I sur l'acétylcholine et la dopamine dans le noyau accumbens." Electronic Thesis or Diss., Sorbonne université, 2024. http://www.theses.fr/2024SORUS098.

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Le stress représente un facteur de risque majeur dans le développement des troubles psychiatriques et des troubles du sommeil. La diversité des réponses émotionnelles au stress résulte de l'influence conjointe de facteurs environnementaux et génétiques. Le noyau accumbens (NAc) joue un rôle central dans la susceptibilité au stress et récemment, son implication dans la régulation du sommeil a été mise en évidence. Les adaptations comportementales liées à la résilience ou la susceptibilité au stress sont modulées par les transmissions dopaminergique et cholinergique au sein du NAc. L'acétylcholi

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7

Etain, Bruno. "Contribution à l'étude des facteurs génétiques et environnementaux de susceptibilité aux troubles bipolaires : études du trouble bipolaire à début précoce et des traumatismes affectifs de l’enfance." Thesis, Paris Est, 2009. http://www.theses.fr/2009PEST0048.

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Les troubles bipolaires (TB) sont des maladies psychiatriques dont le déterminisme complexe fait intervenir des facteurs génétiques et environnementaux de susceptibilité. Les efforts d’identification des facteurs génétiques ont produit des résultats discordants et les facteurs environnementaux restent mal connus. Notre équipe a contribué à identifier une forme à début précoce des TB (TB-DP), son caractère fortement familial en faisant un candidat pour faciliter l’identification de gènes de susceptibilité. Ainsi, nous avons réalisé un criblage systématique du génome dans le TB-DP suggérant une

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8

Jones, C. A. "A study of stress susceptibility in pigs." Thesis, University of Bristol, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.372043.

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9

Thomas, Gladys Ruth. "Susceptibility of Brugia malayi to oxidative and nitrosative stress." Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267808.

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10

鍾慧虹 and Wai-hung Angela Chung. "Cognitive vulnerability, stress, and postpartum depressive symptomatology: a prospective study in HongKong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B37101055.

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11

Shushan, S. M. "The susceptibility of diffusion bonded joints to stress corrosion cracking." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295046.

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12

Chung, Wai-hung Angela. "Cognitive vulnerability, stress, and postpartum depressive symptomatology a prospective study in Hong Kong /." Click to view E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B37101055.

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13

Lorho, Nina. "Stress corrosion cracking susceptibility in Alloy 600 with different strain histories." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/stress-corrosion-cracking-susceptibility-in-alloy-600-with-different-strain-histories(59eabd1d-b254-48bc-afca-e979f5d4e6c2).html.

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Lifetime prediction of components in Alloy 600 is a major concern for nuclear power plants. Alloy 600 components have been shown to be susceptible to stress corrosion cracking (SCC). In the 1990’s, an engineering model was developed in order to predict the life time as a function of the main macroscopic parameters (stress, environment, material), based on laboratory results. This model has since been used to predict the ranking of various Alloy 600 components, using the knowledges of the manufacturing and service conditions for each component. It was applied successfully in the case of forged

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14

Sivathayalan, Sivapathasundaram. "Fabric, initial state and stress path effects on liquefaction susceptibility of sands." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0017/NQ56623.pdf.

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15

Anyanwu, Ezechukwu John. "Low Alloy Steel Susceptibility to Stress Corrosion Cracking in Hydraulic Fracturing Environment." University of Dayton / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1398948610.

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16

Strader, Katherine C. "Phase Transformation Behavior and Stress Relief Cracking Susceptibility in Creep Resistant Steels." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1408973568.

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17

Rozentals, Emils. "Email load and stress impact on susceptibility to phishing and scam emails." Thesis, Luleå tekniska universitet, Digitala tjänster och system, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-85403.

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How does the email load and stress affect the susceptibility to phishing and scam emails? The study was conducted with a Qualitative research approach. Semi-structured interviews were selected for the data gathering. Thematic Analysis was used to analyze Empirical data. This research studied if a high email load affects the likelihood of falling victim to phishing and scam attacks. Research was studied through a theoretical lens of stress, since high email load is subjective for each individual and stress rate can show better how people are perceiving their email load. Findings suggest that hi

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18

Pisu, Davide. "ROLE OF SigE IN M.TUBERCULOSIS DRUG SUSCEPTIBILITY AND PERSISTENCE." Doctoral thesis, Università degli studi di Padova, 2015. http://hdl.handle.net/11577/3424157.

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M.tuberculosis (Mtb) is one of the most important pathogens that infect humans and it is the causative agent of tuberculosis (TB), a disease that dates back to ancient times. The World Health Organization (WHO) estimates that more than one third of the total whole population is infected with Mtb and each year about 1,5 millions people die from tuberculosis. Two of the main problems in M. tuberculosis control are the lengthy treatment and the enormous reservoir of latent carriers. A common explanation for the need of lengthy treatment is that all or part of the population enters a non-replic

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19

Smith, Vincent Peter. "The cuticular membranes of parasitic nematodes : structure, composition and susceptibility to oxidative stress." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267287.

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20

Stenerud, Gaute. "The Susceptibility to Hydrogen Induced Stress Cracking for Alloy 718 and Alloy 725." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for materialteknologi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-26331.

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The Hydrogen Induced Stress Cracking (HISC) susceptibility of Alloy 718 and Alloy 725 where examined and compared. Pre-charged samples of each alloy where stepwise loaded during polarization in Cortest Proof rings. A safe load was found from this stepwise loading. To confirm that these load levels were safe, pre-charged samples were loaded to this load for 30 days during cathodic polarization. After fracture the fracture surfaces were examined in scanning electron microscope and the hydrogen concentration were measured by hydrogen melt extraction. It was found that both alloy are severely embr

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21

Araujo, Alessandra M. "STRESS RESPONSES AND PACE OF LIFE PHENOTYPES PREDICT DISEASE SUSCEPTIBILITY AND HOST EPIZOOTIC POTENTIAL." OpenSIUC, 2015. https://opensiuc.lib.siu.edu/theses/1773.

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This thesis represents two lines of investigation that as a whole integrate physiology and ecology of infectious diseases. While each chapter is a distinct body of work, these studies are linked in that both focus on extrinsic or intrinsic factors influencing hosts’ susceptibility to infection, as well as hosts’ potential to transmit disease. In chapter one, I used a meta-analysis as a tool to review what is known about the stress-linked susceptibility hypothesis, which poses that persistent activation of the stress axis might result in increased disease susceptibility in wild animals, mainly

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22

Cullen, Alexis Elizabeth. "Increased stress susceptibility and hypothalamic-pituitary-adrenal axis dysfunction : early markers of psychosis vulnerability?" Thesis, King's College London (University of London), 2014. http://kclpure.kcl.ac.uk/portal/en/theses/increased-stress-susceptibility-and-hypothalamicpituitaryadrenal-axis-dysfunction(b602f1f0-1006-4491-a112-83d5156f8e13).html.

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Background: Individuals with psychosis are characterised by increased exposure and reactivity to psychosocial stressors and abnormal hypothalamic-pituitary-adrenal (HPA) axis function [i.e., elevated cortisol levels, a blunted cortisol awakening response (CAR), and pituitary volume abnormalities]. The extent to which these features are present among at-risk individuals, prior to illness onset, is currently unclear. Aims: To determine whether putatively at-risk children who present multiple antecedents of schizophrenia (ASz) or a family history of illness (FHx) show increased susceptibility to

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23

Chen, Jinwei. "The effects of specimen geometry of susceptibility to stress corrosion cracking (SCC) of steels." Thesis, University of Newcastle Upon Tyne, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270796.

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24

Coulthard, Jacob, Westley Ongtengco, Jacob Garst, Michelle Chandley, Hui Wang-Heaton, and Gregory A. Ordway. "Oxidative Stress Susceptibility of Oligodendrocytes in Major Depressive Disorder is Widespread in the Brain." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/47.

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Over 10 million people are affected by major depressive disorder (MDD) in the U.S. annually. Unfortunately, about 1/3 of these people do not achieve adequate remission of symptoms with current antidepressant drugs. It is expected that an improved understanding of the pathobiology of depression will result in the development of more effective antidepressant treatments. Research by this lab in recent years has provided evidence of elevated DNA damage in brain white matter in MDD, discovered by studying brain tissues from human brain donors that had an active diagnosis of MDD at the time of dea

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Wodarcyk, John J. "Stress corrosion cracking susceptibility of AISI no. 1018 steel in low SO₂-CO₂-O₂ aqueous environments." Ohio : Ohio University, 1991. http://www.ohiolink.edu/etd/view.cgi?ohiou1183988473.

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26

Roberts, Susan. "The effect of dietary protein source on plasma parameters related to stress and behaviour in pigs varying in their susceptibility to stress /." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=56819.

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The present study was performed to determine if pigs varying in their susceptibility to stress, adapted to a casein-based diet, experience an improvement in biochemical parameters related to stress and behaviour compared to pigs adapted to the traditional western canadian cereal-based swine diet. Experiment 1 involved separating fifty-eight, 8-week old pigs according to genotype with respect to the halothane gene. Within each genotype pigs were divided into 2 groups and assigned to either a control diet or to a diet where most of the protein source was substituted for casein. All animals were

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27

Leech, Alexandra. "Struggling with susceptibility and stress : an exploration and expansion of vulnerability-stress models of depression and the potential for intervention in late adolescence." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608286.

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28

Skjönsberg, Åsa. "Hereditary susceptibility to inner ear stress agents studied in heterozygotes of the German waltzing guinea pig /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-817-7/.

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29

Wodarcyk, John J. Jr. "Stress corrosion cracking susceptibility of AISI No. 1018 steel in low SO 2CO 2O 2aqueous environments." Ohio University / OhioLINK, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1183988473.

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30

Sherwood, Patrick William. "Biochemical Mechanisms of Resistance and Susceptibility in the Pinus nigra - Diplodia sapinea Pathosystem." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1408640310.

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31

Garry, Michael R. "Differential response and susceptibility to oxidative stress in mouse lung fibroblasts heterozygous for phospholipid hydroperoxide glutathione peroxidase (GPx4) /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/8465.

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32

Beal, Irina. "Event Sedimentology and Hydrodynamic Hindcasting of Storm Surge Deposits: Hurricane Sandy, New Jersey." Master's thesis, Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/281770.

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Geology<br>M.S.<br>The impact of Hurricane Sandy (October 2012) on the Atlantic Coast of the United States resulted in massive overtopping (aggradation) of coastal barriers, along with localized overwash and breaching. A combination of high-frequency ground-penetrating radar (800 MHz GPR), low-field magnetic susceptibility (MS), and textural and mineralogical analyses was used to reconstruct the sedimentological and hydrodynamic parameters of the storm surge at two New Jersey sites immediately north of hurricane landfall: 1) Mantoloking and 2) Island Beach State Park (IBSP). Mantoloking repres

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Beal, Irina. "Beal_Calculations.xls." Master's thesis, Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/281771.

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Geology<br>M.S.<br>The impact of Hurricane Sandy (October 2012) on the Atlantic Coast of the United States resulted in massive overtopping (aggradation) of coastal barriers, along with localized overwash and breaching. A combination of high-frequency ground-penetrating radar (800 MHz GPR), low-field magnetic susceptibility (MS), and textural and mineralogical analyses was used to reconstruct the sedimentological and hydrodynamic parameters of the storm surge at two New Jersey sites immediately north of hurricane landfall: 1) Mantoloking and 2) Island Beach State Park (IBSP). Mantoloking repres

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Beal, Irina. "Beal_CAMSIZERdata.xlsx." Master's thesis, Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/281772.

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Geology<br>M.S.<br>The impact of Hurricane Sandy (October 2012) on the Atlantic Coast of the United States resulted in massive overtopping (aggradation) of coastal barriers, along with localized overwash and breaching. A combination of high-frequency ground-penetrating radar (800 MHz GPR), low-field magnetic susceptibility (MS), and textural and mineralogical analyses was used to reconstruct the sedimentological and hydrodynamic parameters of the storm surge at two New Jersey sites immediately north of hurricane landfall: 1) Mantoloking and 2) Island Beach State Park (IBSP). Mantoloking repres

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Chen, Yuanneng. "Role of polymorphisms in genes affecting oxidative stress and immune response in susceptibility to alcoholic liver disease." Thesis, University of Newcastle Upon Tyne, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391248.

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Sanchez, Camacho Lizeth J. ""Effect of AC interference on the corrosion cracking susceptibility of low carbon steel under cathodic protection."." University of Akron / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=akron1531157966071788.

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Ahmed, Ismaila Idowu. "The influence of material factors, including cold work, on the susceptibility of stainless steels to stress corrosion cracking." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/the-influence-of-material-factors-including-cold-work-on-the-susceptibility-of-stainless-steels-to-stress-corrosion-cracking(19937317-f1b4-4dbc-ab0e-3eab3760f716).html.

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The main objective of the thesis was to gain better understanding of key parameters associated with Cold Work (CW) and their possible effects on Stress Corrosion Cracking (SCC) susceptibility of Austenitic Stainless Steels (ASS) cold rolled to different degrees. The microstructural characterisation of the cold rolled ASS was carried out using optical microscopy to determine and correlate the average grain size with the level of CW. The assessment of martensite development during the CW was carried out using the neutron diffraction technique. The effects of CW levels and strain paths on the lat

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Hartley, Deborah Jean. "Anxiety and depression: An empirical investigation of the Diathesis-Stress Model of psychopathology." CSUSB ScholarWorks, 1999. https://scholarworks.lib.csusb.edu/etd-project/1849.

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Taniguchi, Masayuki. "Dopamine D1 receptor subtype mediates acute stress-induced dendritic growth in excitatory neurons of the medial prefrontal cortex and contributes to suppression of stress susceptibility in mice." Kyoto University, 2018. http://hdl.handle.net/2433/232116.

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Gonzalez, Gabriel. "Alterations in Fatty Acid Amide Hydrolase (Faah) Transcript Levels and Activity Lead to Changes in the Abiotic Stress Susceptibility of Arabidopsis Thaliana." Thesis, University of North Texas, 2012. https://digital.library.unt.edu/ark:/67531/metadc115085/.

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N-Acylethanolamines (NAEs) are a class of bioactive lipids, and FAAH is one of the enzymes responsible for degrading NAEs in both plants and animals. in plants, FAAH appears to be closely associated with ABA, a phytohormone which has long been associated with plant stress responses, since the overexpression of FAAH in Arabidopsis results in ABA hypersensitivity. Therefore, it is reasonable to speculate that alterations in FAAH transcript levels will result in altered stress responses in plants. to investigate this hypothesis experiments were carried out in which wild type (WT), FAAH-overexp

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41

Cevik, Gul. "Investigation Of The Effect Of Orientation And Heat Treatment On The Stress Corrosion Cracking Susceptibility Of 7050 Aluminum Alloy." Master's thesis, METU, 2004. http://etd.lib.metu.edu.tr/upload/3/12605220/index.pdf.

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In the present work, the effect of variation in specimen orientation and heat treatment on the Stress Corrosion Cracking (SCC) susceptibility of 7050 aluminum alloy was investigated in 3,5% NaCl solution and under freely corroding conditions. For this purpose, Constant Extension Rate Tests (CERT) was performed on precracked Compact Tension (CT) specimens and the Direct Current Potential Drop technique was applied to measure the crack lengths. In addition to crack length versus time curves, the relationship between the crack growth rate and the stress intensity factor was determined. Fractograp

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42

Duff, Jonathon Andrew. "The influence of grain boundary structure in proton irradiated stainless steel on susceptibility to irradiation assisted stress corrosion cracking." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.496690.

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43

Della, Roverys Coseglio Mario Sergio. "Susceptibility of low-temperature plasma nitrided 17-4 PH (H1150D) to sulphide stress cracking (SSC) in typical oilfield environment." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8488/.

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To attend the growing global demand for energy, oil production—expected to grow in the foreseeable future-relies on the extraction from unconventional resources, such as deep deposits off the coast and ultra-deep water. These environments are contaminated with significant amounts of hydrogen sulphide, a by–product that promotes hydrogen absorp- tion and subsequent failure by sulphide stress cracking (SSC). The 17-4 PH—a stainless steel widely used for oilfield components—is susceptible to SSC, in spite of its favourable combination of properties. In this study, plasma–based treatments, often u

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Hilton, Bruce A. "Irradiation assisted stress corrosion cracking susceptibility of low fluence stainless steels evaluated by in-flux slow strain rate tests." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/42810.

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Smith, Brian Donald. "The influence of high temperature stress and herbicides on the susceptibility of creeping bentgrass (Agrostis palustris) to Curvularia lunata." Thesis, Virginia Polytechnic Institute and State University, 1989. http://hdl.handle.net/10919/74538.

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The status of Curvularia lunata as a primary pathogen of creeping bentgrass (Agrostis palustris) has been debated in the literature for many years. The most recent and most complete evidence indicates that this fungus is a weak pathogen, colonizing only senescing tissues. In the present study, four groups of experiments were conducted: 1) The effects of five herbicides on the growth of C. lunata in vitro were determined. 2) Acute high temperature stress was evaluated as a predisposing factor in the susceptibility of creeping bentgrass to C. lunata. 3) The effects of acute high temperature stre

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Rojas-Rudolph, Isolde Gina. "Stress modulation of susceptibility to wound infection : effects on Leukocyte Trafficking and Chemokine Gene Expression during Cutaneous Wound Healing /." The Ohio State University, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=osu1486474078047403.

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Tanaka, Kohei. "Prostaglandin E2-Mediated Attenuation of Mesocortical Dopaminergic Pathway is Critical for Susceptibility to Repeated Social Defeat Stress in Mice." Kyoto University, 2012. http://hdl.handle.net/2433/158067.

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PALADINI, MARIA SERENA. "STRESS EXPOSURE ACROSS LIFESPAN SHAPES THE CNS SUSCEPTIBILITY TO FURTHER ADVERSE EVENTS: PRECLINICAL EVIDENCE USING A DOUBLE HIT APPROACH." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/694054.

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Stress exposure is known not only to be a risk factor for the development of psychiatric disorders itself, but also to exacerbate other medical conditions, prompting structural and functional changes that can eventually evolve from a normal adaptive body reaction to a pathological state (Gradus, 2017). On this basis, the aim of my PhD project was to investigate at preclinical level how and by which molecular mechanisms stress exposure can leave a signature in the individual, thus increasing the susceptibility of the central nervous system (CNS) to stress-related disorders or aggravating the ou

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Martínez, Membrives Esther. "Susceptibility to experimental autoimmune encephalomyelitis (model of multiple sclerosis) and anxiety in genetically heterogeneous rats." Doctoral thesis, Universitat Autònoma de Barcelona, 2012. http://hdl.handle.net/10803/123299.

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Las respuestas al estrés del eje hipotalámico-pituitario-adrenal (HPA) juegan un papel decisivo tanto en la conducta ansiosa como en el funcionamiento del sistema inmune (IS). Es sabido que los niveles elevados de glucocorticoides (GC) desempeñan un papel protector ante la encefalomielitis experimental autoinmune (EAE), fiable modelo animal de la esclerosis múltiple. En esta Tesis, nos propusimos investigar si un determinado perfil ansioso podría corresponderse con un perfil específico de sensibilidad a la inflamación. En el “Estudio I”, ratas genéticamente heterogéneas N/Nih-HS de ambos sex

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Hedborg, Kerstin. "Migraine and Stress : An Internet administered Multimodal Behavioral Treatment Intervention." Doctoral thesis, Uppsala universitet, Medicin, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-158079.

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Migraine is a disabling neurological disorder with high prevalence, the clinical manifestations of which are highly dependent on stress. The overall theme of the present thesis was to address aspects of stress in migraine. A multimodal behavioral treatment (MBT) program was developed specifically designed for migraine and focusing on stress as a trigger and an intervention was performed using this Internet-administered program. Migraine symptoms were followed via an Internet administered diary and questionnaires were answered at regular intervals during the 11-month study period. The thesis is

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