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Littérature scientifique sur le sujet « T cells Identification »

Auteur : Grafiati
Publié le 4 juin 2021
Mis à jour le 29 janvier 2023

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Articles de revues sur le sujet "T cells Identification"

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Aerts, Nicolaas E., Evelyne J. Dombrecht, Didier G. Ebo, Chris H. Bridts, Wim J. Stevens, and Luc S. De Clerck. "Activated T cells complicate the identification of regulatory T cells in rheumatoid arthritis." Cellular Immunology 251, no. 2 (2008): 109–15. http://dx.doi.org/10.1016/j.cellimm.2008.04.008.

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Graca, Luis, Stephen P. Cobbold, and Herman Waldmann. "Identification of Regulatory T Cells in Tolerated Allografts." Journal of Experimental Medicine 195, no. 12 (June 10, 2002): 1641–46. http://dx.doi.org/10.1084/jem.20012097.

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Induction of transplantation tolerance with certain therapeutic nondepleting monoclonal antibodies can lead to a robust state of peripheral “dominant” tolerance. Regulatory CD4+ T cells, which mediate this form of “dominant” tolerance, can be isolated from spleens of tolerant animals. To determine whether there were any extra-lymphoid sites that might harbor regulatory T cells we sought their presence in tolerated skin allografts and in normal skin. When tolerated skin grafts are retransplanted onto T cell–depleted hosts, graft-infiltrating T cells exit the graft and recolonize the new host. T
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Souter, M. N., C. V. Nguyen-Robertson, F. J. Ross, S. J. J. Reddiex, J. Waddington, I. Van Rhijn, S. B. G. Eckle, et al. "Identification and characterization of CD1-restricted T cells." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 206.6. http://dx.doi.org/10.4049/jimmunol.196.supp.206.6.

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Abstract Most studies of T cells have focused on those that respond to foreign peptides. However, other specialized populations of T cells exist that recognize lipid antigens and make up a substantial component of the human immune system. These lipid reactive T cells recognize antigens presented by antigen presentation molecules from the CD1 family. Four CD1 molecules exist (CD1a, CD1b, CD1c and CD1d), and each is capable of presenting a unique repertoire of lipids antigens to T cells. Much of what we have learned about lipid reactive T cells stems from studies of CD1d restricted NKT cells as
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Illes, Z., T. Kondo, K. Yokoyama, T. Ohashi, T. Tabira, and T. Yamamura. "Identification of autoimmune T-cells among in vivo expanded CD25+ T-cells in multiple sclerosis." Journal of Neuroimmunology 90, no. 1 (September 1998): 73. http://dx.doi.org/10.1016/s0165-5728(98)91617-4.

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Illés, Zsolt, Takayuki Kondo, Kazumasa Yokoyama, Takashi Ohashi, Takeshi Tabira, and Takashi Yamamura. "Identification of Autoimmune T Cells Among In Vivo Expanded CD25+ T Cells in Multiple Sclerosis." Journal of Immunology 162, no. 3 (February 1, 1999): 1811–17. http://dx.doi.org/10.4049/jimmunol.162.3.1811.

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Abstract Although clonal expansion of autoimmune T cells has been reported in multiple sclerosis (MS), very limited information is available on specificities, clonal size, or activation state of the expanded clones. Here we address the issue of clonal expansion by using a novel technique demonstrating clonotypes defined by single-strand conformation polymorphism of TCR β-chain cDNAs. Examination of activated T cells (CD3+CD25+) isolated from the peripheral blood of MS revealed limited numbers (20∼82) of expanded clones defined by single-strand conformation polymorphism clonotype. To estimate t
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Baseggio, L., F. Berger, D. Morel, M.-h. Delfau-Larue, G. Goedert, G. Salles, J.-p. Magaud, and P. Felman. "Identification of circulating CD10 positive T cells in angioimmunoblastic T-cell lymphoma." Leukemia 20, no. 2 (December 8, 2005): 296–303. http://dx.doi.org/10.1038/sj.leu.2404013.

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Azimi, Maryam, Saeed Aslani, Sahar Mortezagholi, Amir Salek, Mohammad Reza Javan, Alireza Rezaiemanesh, Mojgan Ghaedi, Mehrdad Gholamzad, and Eisa Salehi. "Identification, Isolation, and Functional Assay of Regulatory T Cells." Immunological Investigations 45, no. 7 (July 15, 2016): 584–602. http://dx.doi.org/10.1080/08820139.2016.1193869.

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Kobayashi, Hiroya, and Esteban Celis. "Peptide epitope identification for tumor-reactive CD4 T cells." Current Opinion in Immunology 20, no. 2 (April 2008): 221–27. http://dx.doi.org/10.1016/j.coi.2008.04.011.

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Gerli, Roberto, Giuseppe Nocentini, Alessia Alunno, Elena Bartoloni Bocci, Rodolfo Bianchini, Onelia Bistoni, and Carlo Riccardi. "Identification of regulatory T cells in systemic lupus erythematosus." Autoimmunity Reviews 8, no. 5 (March 2009): 426–30. http://dx.doi.org/10.1016/j.autrev.2009.01.004.

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Cardarelli, P. M., and M. D. Pierschbacher. "Identification of fibronectin receptors on T lymphocytes." Journal of Cell Biology 105, no. 1 (July 1, 1987): 499–506. http://dx.doi.org/10.1083/jcb.105.1.499.

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We report the identification of fibronectin receptors on thymocytes and T lymphoma cells. Affinity chromatography of extracts of the T cell lymphoma, WR16.1, on a fibronectin-Sepharose column combined with specific elution using a synthetic peptide containing the cell attachment-promoting sequence, arginine-glycine-aspartic acid, yielded two polypeptide components having apparent molecular masses of approximately 160 kD reduced and 175 and 150 kD nonreduced. Immunoprecipitations from surface-iodinated WR16.1 cells or fibronectin-adherent thymocytes using a rabbit antiserum raised against the f
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Thèses sur le sujet "T cells Identification"

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Ye, Song Cheung H. Tak. "Identification of a thymic extracellular matrix protein that promotes strong thymocyte adhesion." Normal, Ill. Illinois State University, 1990. http://wwwlib.umi.com/cr/ilstu/fullcit?p9115234.

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Thesis (Ph. D.)--Illinois State University, 1990.<br>Title from title page screen, viewed December 2, 2005. Dissertation Committee: H. Tak Cheung (chair), Herman Brockman, Harry Huizinga, Anthony Otsuka, Brian Wilkinson. Includes bibliographical references (leaves 116-127) and abstract. Also available in print.
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Wang, Min-Guang Cheung H. Tak. "Identification of an extracellular matrix epitope involved in T cell adhesion." Normal, Ill. Illinois State University, 1992. http://wwwlib.umi.com/cr/ilstu/fullcit?p9311292.

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Thesis (Ph. D.)--Illinois State University, 1992.<br>Title from title page screen, viewed February 7, 2006. Dissertation Committee: H. Tak Cheung (chair), Mathew J. Nadakavukaren, Alan J. Katz, Brian J. Wilkinson, Lynne A. Lucher. Includes bibliographical references (leaves 103-114) and abstract. Also available in print.
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Garefalaki, Anna. "Identification of regulatory regions that determine expression of murine CD8 locus." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250198.

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Robinson, Jonathan Matthew. "Identification of tumour-specific T-cells in colorectal cancer patients." Thesis, University of Leeds, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485913.

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The ability to induce an immune response to a tumour is an attractive approach to cancer treatment, particularly when used in combination with surgery and chemotherapy or radiotherapy. In theory the use of such immunological techniques should be possible to help treat colorec~ cancer. Immunotherapy has shown encouraging results in the treatment of other cancers, namely malignant melanoma and renal cell c¥cinoma: The ability of these techniques to aid the treatment of advanced colorectal cancer has so far proved disappointing, although some encouragement has been observed. It has recently be
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Hansson, Johan. "Activation and differentiation of cytotoxic T lymphocytes identification of district CTL subsets in the rat /." Lund : Dept. of Tumor Immunology, the Wallenberg Laboratory, 1994. http://catalog.hathitrust.org/api/volumes/oclc/39158589.html.

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Lam, Eric M. "IDENTIFICATION OF CYCLIN-DEPENDENT KINASE 5 IN T CELLS AND ITS ROLE IN REGULATING T CELL FUNCTION AND DIFFERENTIATION." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1422014852.

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Ulaganathan, Vijay Kumar. "Gene Expression Profiling of Encephalitogenic CD4+ T cells: Identification of Genes Controlling Migration of Effector T cells into the CNS." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-122549.

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Bosco, Anthony. "Identification of novel genes associated with allergen-driven T cell activation in human atopics /." Connect to this title, 2006. http://theses.library.uwa.edu.au/adt-WU2007.0023.

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Pandey, Shubham. "Identification of Interleukin 4 - CXCL12 supportive loop in follicular lymphoma." Thesis, Rennes 1, 2016. http://www.theses.fr/2016REN1B031/document.

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Le lymphome folliculaire (FL) est le lymphome B indolent le plus fréquent. Outre des altérations géniques récurrentes, le micro-environnement tumoral, et notamment les cellules stromales lymphoides,joue un rôle majeur dans le développement de ce cancer. Cependant, la caractérisation in-situ des cellules stromales lymphoïdes chez l'homme tout comme les facteurs menant à la polarisation du stroma en un stroma protumoral ont été peu étudiés. Dans cette thèse, nous avons montré, que les cellules stromales présentes dans les ganglions et la moelle osseuse envahis des patients atteints de FL surexpr
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Bosco, Anthony. "Identification of novel genes associated with allergen-driven T cell activation in human atopics." University of Western Australia. School of Paediatrics and Child Health, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0023.

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[ Truncated abstract ] Atopic diseases such as asthma are thought to be driven to a significant extent by T helper memory cells which are programmed to respond in a harmful way to environmental allergens (e.g. house dust mite). Previous studies in humans and in animal models have established that activation of TH2 cytokine genes in T memory responses to allergens is central to the disease process. However, only a subset of atopics harbouring a TH2-memory response phenotype manifests clinical symptoms of disease. Moreover, clinical trials with TH2 antagonists in atopic patients have proven dis
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Livres sur le sujet "T cells Identification"

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Sjoerd Henricus van der Burg. Identification and evaluation of cytotoxic T-cell epitopes in HIV-1 and tumour-associated proteins. [Leiden: University of Leiden, 1998.

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Loreto, Michael Peter. Identification and characterization of Src-like adaptor protein-2, a novel hematopoietic-specific adaptor protein and inhibitor of T-cell receptor signaling. Ottawa: National Library of Canada, 2002.

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Identification and characterization of murine TCR [gamma] [delta]-expressing peripheral T cells. 1990.

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Muthukumar, Thangamani, Darshana Dadhania, Choli Hartono, and Manikkam Suthanthiran. Immunology, sensitization, and histocompatibility. Edited by Jeremy R. Chapman. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0279.

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Allograft rejection of the histo-incompatible allograft involves a highly orchestrated action of multiple cell types and mediators, with lymphocytes responsible for the identification of the foreignness of the allograft. The immune response directed against the donor is primarily, but not exclusively, directed at the donor’s major histocompatibility complex region class I and class II proteins. This chapter describes the immunobiology of the T cell and the role of human leucocyte antigens in clinical transplantation, thus identifying the targets for manipulation of the immune response by immun
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Liu, Stanley Kai-Wei. Identification and characterization of Gads - a novel hematopoietic-specific adaptor protein - in T cell receptor signaling. 2000.

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Rodríguez, Richard T. A Kiss across the Ocean. Duke University Press, 2022. http://dx.doi.org/10.1215/9781478023180.

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In A Kiss across the Ocean Richard T. Rodríguez examines the relationship between British post-punk musicians and their Latinx audiences in the United States since the 1980s. Melding memoir with cultural criticism, Rodríguez spotlights a host of influential bands and performers including Siouxsie and the Banshees, Adam Ant, Bauhaus, Soft Cell, Frankie Goes to Hollywood, and Pet Shop Boys. He recounts these bands’ importance for him and other Latinx kids and discusses their frequent identification with these bands’ glamorous performance of difference. Whether it was Siouxsie Sioux drawing inspi
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E, Menitove Jay, Kolins Jerry, American Association of Blood Banks. Committee on Technical/Scientific Workshops., and AIDS Technical Workshop (1986 : San Francisco, Calif.), eds. AIDS. Arlington, Va: American Association of Blood Banks, 1986.

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Chapitres de livres sur le sujet "T cells Identification"

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Gielis, Sofie, Pieter Moris, Wout Bittremieux, Nicolas De Neuter, Benson Ogunjimi, Kris Laukens, and Pieter Meysman. "Identification of Epitope-Specific T Cells in T-Cell Receptor Repertoires." In Bioinformatics for Cancer Immunotherapy, 183–95. New York, NY: Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0327-7_13.

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Wacleche, Vanessa S., Runci Wang, and Deepak A. Rao. "Identification of T Peripheral Helper (Tph) Cells." In Methods in Molecular Biology, 59–76. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1736-6_6.

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Courey-Ghaouzi, Alan, and Mauro Gaya. "Identification of Non-classical Follicular T Cells." In Methods in Molecular Biology, 77–84. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1736-6_7.

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Leehan, Kerry M., and Kristi A. Koelsch. "T Cell ELISPOT: For the Identification of Specific Cytokine-Secreting T Cells." In Methods in Molecular Biology, 427–34. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2694-7_43.

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Beverley, P. C. L., M. Merkenschlager, and D. L. Wallace. "Identification of Human Naive and Memory T Cells." In Progress in Immunology, 432–38. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-83755-5_57.

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Georgiev, Hristo, Georgia Papadogianni, and Günter Bernhardt. "Identification of Follicular T Cells in the Gut." In Methods in Molecular Biology, 85–95. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1736-6_8.

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Ding, Yanna, John D. Mountz, and Hui-Chen Hsu. "Identification of Follicular T Helper Cells in Tissue Sections." In Methods in Molecular Biology, 13–25. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2498-1_2.

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Koffeman, Eva, Elissa Keogh, Mark Klein, Berent Prakken, and Salvatore Albani. "Identification and Manipulation of Antigen Specific T-Cells with Artificial Antigen Presenting Cells." In Arthritis Research, 69–86. Totowa, NJ: Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-402-5_6.

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Pedroso, Rodrigo, Filipa Ribeiro, Ana Rita Pires, Luis Graca, and Valter R. Fonseca. "Identification of Human T Follicular Cells in Ectopic Lymphoid Structures." In Methods in Molecular Biology, 225–33. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1736-6_19.

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Meli, Alexandre P., and Irah L. King. "Identification of Mouse T Follicular Helper Cells by Flow Cytometry." In Methods in Molecular Biology, 3–11. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2498-1_1.

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Actes de conférences sur le sujet "T cells Identification"

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Roos-Engstrand, Ester, Anders Bucht, Anders Blomberg, Annelie Behndig, and Jamshid Pourazar. "Identification Of Regulatory T Cells In Stable COPD." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3880.

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Naradikian, Martin S., Leslie Montero, Samantha Hall, Milad Bahmanof, Rukman Thota, Luise Sternberg, Jerome Lane, et al. "Abstract 1439: Identification and characterization of neoantigen specific T cells." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-1439.

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Naradikian, Martin S., Leslie Montero, Samantha Hall, Milad Bahmanof, Rukman Thota, Luise Sternberg, Jerome Lane, et al. "Abstract 1439: Identification and characterization of neoantigen specific T cells." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-1439.

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Codd, A., S. Al-Taei, S. Tokita, E. Mizushima, P. Rizkallah, T. Kanaseki, T. Torigoe, S. Man, and Z. Tabi. "PO-407 Identification of unique antigens on prostate cancer stem cells for cytotoxic T cell recognition." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.918.

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Mathieu, Mélissa, Sandy Pelletier, David Laperrière, Sylvie Mader, and Simon Turcotte. "Abstract A084: Identification of mutation-reactive T cells in patients with gastrointestinal cancers." In Abstracts: CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival; September 16-19, 2015; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr15-a084.

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Chen, Liang, Chunlin Wang, and Mark Davis. "Abstract PR14: Identification of specificity TCR groups of tumor antigen specific T-cells." In Abstracts: Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival; September 30 - October 3, 2018; New York, NY. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr18-pr14.

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Hudson, Will H., Julia L. Gensheimer, Haydn T. Kissick, and Rafi Ahmed. "Abstract A196: Systematic identification of markers and drug targets on exhausted CD8+ T-cells." In Abstracts: Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival; September 30 - October 3, 2018; New York, NY. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr18-a196.

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Chen, Jia-Shing, and H. Sunny Sun. "Abstract 3852: Identification and functional characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2) in neuronal cells." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3852.

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Zong, Yunhui, Fuliang Chu, Songbing He, Yu Jing, Sally A. Hunsucker, Tina Yang, Ming Zhang, et al. "Abstract 4094: Identification of co-inhibitory receptor expression on T cells from gastric cancer patients." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4094.

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Bessede, Alban, Florent Peyraud, Jean Philippe Guegan, Christophe Rey, Sylvestre Le Moulec, Fabrice Barlesi, Sophie Cousin, et al. "135 Identification of super-exhausted T cells: a novel population predictive of response to immunotherapy." In SITC 37th Annual Meeting (SITC 2022) Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/jitc-2022-sitc2022.0135.

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Rapports d'organisations sur le sujet "T cells Identification"

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Baszler, Timothy, Igor Savitsky, Christopher Davies, Lauren Staska, and Varda Shkap. Identification of bovine Neospora caninum cytotoxic T-lymphocyte epitopes for development of peptide-based vaccine. United States Department of Agriculture, March 2006. http://dx.doi.org/10.32747/2006.7695592.bard.

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The goal of the one-year feasibility study was to identify specific cytotoxic T-lymphocyte (CTL) epitopes to Neosporacaninum in the natural bovine host in order to make progress toward developing an effective peptide-based vaccine against bovine neosporosis. We tested the hypothesis that: N. caninum SRS2 peptides contain immunogenicCTLepitope clusters cross-presented by multiple bovine MHC-I and MHC-IIhaplotypes. The specific objectives were: (1) Map bovine CTLepitopes of N. caninum NcSRS-2 and identify consensus MHC-I and class-II binding motifs; and (2) Determine if subunit immunization with
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Epel, Bernard, and Roger Beachy. Mechanisms of intra- and intercellular targeting and movement of tobacco mosaic virus. United States Department of Agriculture, November 2005. http://dx.doi.org/10.32747/2005.7695874.bard.

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To cause disease, plant viruses must replicate and spread locally and systemically within the host. Cell-to-cell virus spread is mediated by virus-encoded movement proteins (MPs), which modify the structure and function of plasmodesmata (Pd), trans-wall co-axial membranous tunnels that interconnect the cytoplasm of neighboring cells. Tobacco mosaic virus (TMV) employ a single MP for cell- cell spread and for which CP is not required. The PIs, Beachy (USA) and Epel (Israel) and co-workers, developed new tools and approaches for study of the mechanism of spread of TMV that lead to a partial iden
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Lillehoj, Hyun, Dan Heller, and Mark Jenkins. Cellular and molecular identification of Eimeria Acervulina Merozoite Antigens eliciting protective immunity. United States Department of Agriculture, November 1992. http://dx.doi.org/10.32747/1992.7561056.bard.

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Coccidiosis, ubiquitous diseases of poultry, seriously impair the growth and feed utilization of livestock and poultry. Coccidiosis causes over $600 million annual losses world-wide and no vaccine is currently available. The goal of this study was to investigate the cellular and molecular mechanisms controlling protective immune responses to coccidia parasites in order to develop immunological control strategy against coccidiosis. The major findings of this study were: 1) cell-mediated immunity plays a major role in protection against coccidiosis, 2) when different genetic lines showing differ
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Eldar, Avigdor, and Donald L. Evans. Streptococcus iniae Infections in Trout and Tilapia: Host-Pathogen Interactions, the Immune Response Toward the Pathogen and Vaccine Formulation. United States Department of Agriculture, December 2000. http://dx.doi.org/10.32747/2000.7575286.bard.

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In Israel and in the U.S., Streptococcus iniae is responsible for considerable losses in various fish species. Poor understanding of its virulence factors and limited know-how-to of vaccine formulation and administration are the main reasons for the limited efficacy of vaccines. Our strategy was that in order to Improve control measures, both aspects should be equally addressed. Our proposal included the following objectives: (i) construction of host-pathogen interaction models; (ii) characterization of virulence factors and immunodominant antigens, with assessment of their relative importance
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Shpigel, Nahum, Raul Barletta, Ilan Rosenshine, and Marcelo Chaffer. Identification and characterization of Mycobacterium paratuberculosis virulence genes expressed in vivo by negative selection. United States Department of Agriculture, January 2004. http://dx.doi.org/10.32747/2004.7696510.bard.

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Mycobacterium avium subsp. paratuberculosis (MAP) is the etiological agent of a severe inflammatory bowel disease (IBD) in ruminants, known as Johne’s disease or paratuberculosis. Johne’s disease is considered to be one of the most serious diseases affecting dairy cattle both in Israel and worldwide. Heavy economic losses are incurred by dairy farmers due to the severe effect of subclinical infection on milk production, fertility, lower disease resistance and early culling. Its influence in the United States alone is staggering, causing an estimated loss of $1.5 billion to the agriculture indu
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Ron, Eliora, and Eugene Eugene Nester. Global functional genomics of plant cell transformation by agrobacterium. United States Department of Agriculture, March 2009. http://dx.doi.org/10.32747/2009.7695860.bard.

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The aim of this study was to carry out a global functional genomics analysis of plant cell transformation by Agrobacterium in order to define and characterize the physiology of Agrobacterium in the acidic environment of a wounded plant. We planed to study the proteome and transcriptome of Agrobacterium in response to a change in pH, from 7.2 to 5.5 and identify genes and circuits directly involved in this change. Bacteria-plant interactions involve a large number of global regulatory systems, which are essential for protection against new stressful conditions. The interaction of bacteria with
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Firon, Nurit, Prem Chourey, Etan Pressman, Allen Hartwell, and Kenneth J. Boote. Molecular Identification and Characterization of Heat-Stress-Responsive Microgametogenesis Genes in Tomato and Sorghum - A Feasibility Study. United States Department of Agriculture, October 2007. http://dx.doi.org/10.32747/2007.7591741.bard.

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Exposure to higher than optimal temperatures - heat-stress (HS) - is becoming increasingly common to all crop plants worldwide. Heat stress coinciding with microgametogenesis, especially during the post-meiotic phase that is marked by starch biosynthesis, is often associated with starch-deficient pollen and male sterility and ultimately, greatly reduced crop yields. The molecular basis for the high sensitivity of developing pollen grains, on one hand, and factors involved in pollen heat-tolerance, on the other, is poorly understood. The long-term goal of this project is to provide a better und
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Altstein, Miriam, and Ronald J. Nachman. Rational Design of Insect Control Agent Prototypes Based on Pyrokinin/PBAN Neuropeptide Antagonists. United States Department of Agriculture, August 2013. http://dx.doi.org/10.32747/2013.7593398.bard.

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The general objective of this study was to develop rationally designed mimetic antagonists (and agonists) of the PK/PBAN Np class with enhanced bio-stability and bioavailability as prototypes for effective and environmentally friendly pest insect management agents. The PK/PBAN family is a multifunctional group of Nps that mediates key functions in insects (sex pheromone biosynthesis, cuticular melanization, myotropic activity, diapause and pupal development) and is, therefore, of high scientific and applied interest. The objectives of the current study were: (i) to identify an antagonist bioph
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Lers, Amnon, and Pamela J. Green. Analysis of Small RNAs Associated with Plant Senescence. United States Department of Agriculture, March 2013. http://dx.doi.org/10.32747/2013.7593393.bard.

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Senescence is an agriculturally significant process due to its negative impact to crop yield and postharvest quality. The genetic regulatory systems controlling senescence induction and progress respond to both developmental and environmental stress signals and involve numerous gene expression changes. Knowledge about the key molecular factors which control senescence is very limited. MicroRNAs (miRNAs) are a class of small RNAs which typically function by guiding cleavage of target messenger RNAs. They have been shown to play major roles in a variety of plant processes including development,
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