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Articles de revues sur le sujet « TARS2 »

Auteur : Grafiati
Publié le 9 mars 2023
Mis à jour le 19 juillet 2025

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1

Paripović, A., A. Maver, N. Stajić, et al. "Expanding the Phenotypic Spectrum: Chronic Kidney Disease in a Patient with Combined Oxidative Phosphorylation Defect 21." Balkan Journal of Medical Genetics 26, no. 2 (2023): 59–64. http://dx.doi.org/10.2478/bjmg-2023-0016.

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Abstract Introduction Pathogenic variants in TARS2 are associated with combined oxidative phosphorylation deficiency 21 (COXPD21), an autosomal recessive disorder usually presenting as mitochondrial encephalomyopathy. Kidney impairment has been documented in a minority of COXPD21 patients, mostly with distal renal tubular acidosis. Case report We report on the first COXPD21 patient with generalized tubular dysfunction and early childhood progression to chronic kidney disease (CKD). Thorough diagnostic evaluation was initiated at six months of age due to failure to thrive, muscular hypotonia, motor delay and recurrent bronchiolitis. The boy was lost to follow-up until the age of two years, when he was readmitted with elevated creatinine level, reduced estimated glomerular filtrate rate, normochromic anaemia, metabolic acidosis and hyperkalaemia. Urine abnormalities pointed to generalized tubular dysfunction. Two novel heterozygous missense variants in TARS2 gene were detected by the means of whole exome sequencing: c.1298T>G (p.Phe438Cys) of maternal origin and c.1931A>T (p.Asp644Val) of paternal origin. Currently, at 4.5 years of age, the boy has failure to thrive, severe motor and verbal delay and end stage of CKD. We referred the patient to paediatric centre that provides renal replacement therapy. Conclusion The overall clinical course in the patient we report on corresponds well to the previously reported cases of TARS2 related COXPD21, especially in regard to neurological and developmental aspects of the disease. However, we point out the generalized tubulopathy and early occurrence of CKD in our patient as atypical renal involvement in COXPD21. Additionally, this is the first report of hypothyroidism and hypoparathyroidism in a COXPD21 patient.
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S, MURUGESAN, MURUGAN E, and NADARAJAN N. "BREEDING FOR IMPROVED PLANT TYPE IN PIGEONPEA." Madras Agricultural Journal 84, January (1997): 12–14. http://dx.doi.org/10.29321/maj.10.a00830.

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An attempt was made to breed for improved plant type in pigeonpen by crossing two contrasting parents viz. Vamban-I and Gulbarga-1. The F2 population clearly segregated into four distinct classes of phenotypes (plant types) in the ratio of 50 intermediate erect tall: 14 compact dwarf in the early segregants and 15 tall spreading: 1 compact bushy in the late segregants indicating that the plant type in pigeonpea was controlled by interaction of two pairs of non-allelic linkage blocks designated as DTCLSI and TALS2 and their respective allelic blocks as dtclsl and tais2.
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Zhou, Xiao-Long, Yun Chen, Qi-Yu Zeng, Zhi-Rong Ruan, Pengfei Fang, and En-Duo Wang. "Newly acquired N-terminal extension targets threonyl-tRNA synthetase-like protein into the multiple tRNA synthetase complex." Nucleic Acids Research 47, no. 16 (2019): 8662–74. http://dx.doi.org/10.1093/nar/gkz588.

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Abstract A typical feature of eukaryotic aminoacyl-tRNA synthetases (aaRSs) is the evolutionary gain of domains at either the N- or C-terminus, which frequently mediating protein–protein interaction. TARSL2 (mouse Tarsl2), encoding a threonyl-tRNA synthetase-like protein (ThrRS-L), is a recently identified aaRS-duplicated gene in higher eukaryotes, with canonical functions in vitro, which exhibits a different N-terminal extension (N-extension) from TARS (encoding ThrRS). We found the first half of the N-extension of human ThrRS-L (hThrRS-L) is homologous to that of human arginyl-tRNA synthetase. Using the N-extension as a probe in a yeast two-hybrid screening, AIMP1/p43 was identified as an interactor with hThrRS-L. We showed that ThrRS-L is a novel component of the mammalian multiple tRNA synthetase complex (MSC), and is reliant on two leucine zippers in the N-extension for MSC-incorporation in humans, and mouse cell lines and muscle tissue. The N-extension was sufficient to target a foreign protein into the MSC. The results from a Tarsl2-deleted cell line showed that it does not mediate MSC integrity. The effect of phosphorylation at various sites of hThrRS-L on its MSC-targeting is also explored. In summary, we revealed that ThrRS-L is a bona fide component of the MSC, which is mediated by a newly evolved N-extension domain.
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Schlichting, J. E. P. T. "Tarsp." Taalverwerving in onderzoek 30 (January 1, 1988): 81–92. http://dx.doi.org/10.1075/ttwia.30.08ver.

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In this article a preliminary report is given of a research project concerning a Dutch version of Crystal, Fletcher & Garman's LARSP, Language Assessment Remediation and Screening Procedure, a gram-matical developmental scale for the use of language therapy. The first Part of the project consisted of a longitudinal study of 15 children between 1;3 and 3;6 with six monthly spontaneous language samples per child. The result of this study showed that the most striking and stable characteristic of grammatical development till the age of four was the increasing number of constituents in the sentence (with the Declarative sentence having one more constituent than the Command and the Question in all stages, compare Wells, 1985). Based on this a cross-sectional study was carried out with the number of constituents of the Declarative or the same number minus one in and Q as a language measure. After assigning the 100 children involved to the seven stages of the Dutch TARSP, the lower language level part of the scale was constructed: Wordgroups, Connectives, Pronouns and Word Structure. The Dutch version of TARSP is compared to a smal-ler Dutch study based on LARSP with a different methodological set-up: GRAMAT.
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Jang, Ki Beom, Agus Suryawan, Marta L. Fiorotto, and Teresa A. Davis. "PSII-18 Prematurity alters nutrient signaling and protein synthesis in skeletal muscle of neonatal piglets." Journal of Animal Science 102, Supplement_3 (2024): 694–95. http://dx.doi.org/10.1093/jas/skae234.783.

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Abstract Extrauterine growth restriction is common in infants born preterm, and negatively affects lean mass accretion and health. Prematurity has been shown to inhibit the feeding-induced stimulation of protein synthesis in skeletal muscle. We hypothesized that nutrient signaling, activation of the mechanistic target of rapamycin complex 1 (mTORC1), and protein synthesis in the muscle are limited in preterm infants which negatively impacts muscle growth. The objective of this study was to examine how prematurity influences the mechanisms involved in insulin- and amino acid-induced signaling and protein synthesis in skeletal muscle of piglets delivered either 9 d preterm (104 d, n = 25) or at term (112 d, n = 26) by cesarean section. After resuscitation, they were surgically implanted with jugular vein and carotid artery catheters and placed in individual incubators. They were randomly allotted to one of three treatments within each preterm and term birth groups: euaminoacidemic-euglycemic (FAST), hyperinsulinemic-euaminoacidemic-euglycemic (INS), or euinsulinemic-hyperaminoacidemic-euglycemic (AA) clamps on 4 d after birth. After the clamp procedure, the piglets were euthanized to collect longissimus dorsi muscle for estimating in vivo fractional protein synthesis rates and the abundance and activation of components related to insulin and amino acid signaling. Data were analyzed using the MIXED procedure of SAS. The leucine sensor, Sestrin1 bound to GATOR2 (P < 0.05) was reduced in response to AA whereas the abundance of the mTOR-RagA and mTOR-RagC complexes increased (P < 0.05). The phosphorylation of Akt was increased (P < 0.05) in response to INS and the phosphorylation of mTORC1 and protein synthesis increased (P < 0.05) in response to both AA and INS. Prematurity did not affect the protein abundances of the AA transporters for glutamine (SLC38A2), leucine (SLC7A5), and arginine (SLC38A9). However, prematurity reduced (P < 0.05) the abundances of the leucine sensors SAR1B, the Sestrin1-GATOR complex, the AA sensor, RAB1A, and the threonine sensor, TARS2 (P < 0.05). The abundances of the glutamine sensor, ARF1, the arginine sensor, CASTOR, and the methionine-SAMTOR GATOR complex were similar. Prematurity reduced (P < 0.05) the abundance of the mTOR-RagA and mTOR-RagC complexes, the phosphorylation of mTORC1 and muscle protein synthesis (P < 0.05). In conclusion, prematurity negatively affects protein synthesis in skeletal muscle of neonatal preterm piglets by blunting anabolic pathways responsible for nutrient-sensing and mTORC1 activation. The reduced anabolic response likely contributes to reduced lean growth and extrauterine growth restriction following preterm birth.
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Takagi, Satoshi, Tianyi Huang, and Ryohei Katayama. "Abstract 2986: Genomic amplification of MCL1 as a therapeutic target for osteosarcoma." Cancer Research 85, no. 8_Supplement_1 (2025): 2986. https://doi.org/10.1158/1538-7445.am2025-2986.

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Osteosarcoma (OS) is the most common primary malignant bone tumor that predominantly occurs in children, adolescents, and young adults. The treatment for OS that combines surgery with chemotherapy, which consists of a four-drug combination of doxorubicin (DOX), cisplatin (CDDP), high-dose methotrexate (MTX), and ifosfamide, was established in 1970s, and it is still used as a standard therapy. The lack of progress in drug development for OS is partly due to unidentified actionable oncogenic drivers common to OS. In this study, we demonstrate that copy number gains of MCL1 frequently occur in OS, leading to increased vulnerability to therapies based on Mcl-1 inhibitors. Fluorescence in situ hybridization analysis of formalin-fixed paraffin-embedded specimens revealed MCL1 amplification in 46.3% of patients with OS at the JFCR hospital (N = 41). Furthermore, analysis of the TARGET OS dataset, which comprises pediatric patients with OS (N = 81), found that the frequency of MCL1 amplification was notably higher, at 70.4%. Genetic inhibition of MCL1 induced significant apoptosis in MCL1-amplified OS cells. Pharmacological inhibition of MCL1 demonstrated a negative correlation between MCL1 copy numbers and sensitivity to Mcl-1 inhibitors, including MIK665 and AZD5991, with a Pearson’s r value of -0.65 (p = 0.03) across OS cell lines. The chromosome 1q21.2-3 region, where MCL1 is located, contains multiple genes related to the IGF-1R/PI3K pathway, including PIP5K1A, TARS2, OUTD7B, and ENSA, which also showed increased copy numbers in MCL1-amplified OS cells. Additionally, the combination of MIK665 with IGF-1R inhibitors, including OSI906, AEW541, and AZD3463, induced synergistic cell death by overcoming drug tolerance conferred by the activation of IGF signaling in OS cells. In a NOS-10 (which has 16 copies of MCL1) xenograft model, MIK665 significantly suppressed tumor growth, and its antitumor effect was remarkably enhanced by combining with OSI906. This trend was also observed in a NOS-1 (with 5 copies of MCL1) xenograft model, but the enhancement was more modest than in the NOS-10 model. Moreover, the combination therapy of AZD5991 with OSI906 also reduced tumor growth in the NOS-10 xenograft model. These results suggest that genomic amplification of MCL1 in the 1q21.2-3 region, observed in nearly half of OS patients, may act as a predictive biomarker for combination therapy with an Mcl-1 inhibitor and an IGF1-R inhibitor. Citation Format: Satoshi Takagi, Tianyi Huang, Ryohei Katayama. Genomic amplification of MCL1 as a therapeutic target for osteosarcoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts); 2025 Apr 25-30; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2025;85(8_Suppl_1):Abstract nr 2986.
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Dufour, Michel. "Tarse antérieur." Kinésithérapie, la Revue 15, no. 164-165 (2015): 20–22. http://dx.doi.org/10.1016/j.kine.2015.05.007.

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Park, Chul-Hyun. "Prevalence of AALTF and relevant associated MR findings in persons with and without sinus tarsi pain." Foot & Ankle Orthopaedics 3, no. 3 (2018): 2473011418S0037. http://dx.doi.org/10.1177/2473011418s00377.

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Category: Ankle Introduction/Purpose: Sinus tarsi pain is very common, however, etiology of this condition has not been well understood. The purpose of this study was to evaluate differences of MRI findings between persons with and without sinus tarsi pain and to investigate the relationships of sinus tarsi pain and accessory anterolateral talar facet (AALTF). Methods: We reviewed MR images of 120 ankles with sinus tarsi pain in 115 consecutively registered patients. And age- and sex-matched MR images of 120 ankles without pain were also reviewed. We compared the presence of AALTF, calcaneal cyst (CC), bone marrow edema (BME), sinus tarsi fat obliteration (STFO) at the Gissane angle, and coalition between persons with and without sinus tarsi pain. We also compared Gissane angle, talar infero-lateral surface angle (TILSA), and calcaneal cortical thickness (CCT). Of persons with sinus tarsi pain, we compared these parameters between persons with and without AALTF. Results: AALTF was present in 61 ankles (50.8%) with sinus tarsi pain and 34 ankles (28.3%) without sinus tarsi pain (P<0.001). BME (P=0.001) and STFO (P=0.009) were significantly more frequent in persons with sinus tarsi pain. Presences of CC (P=0.108) and coalition (P=0.605) were not different. The Gissane angle was significantly smaller in persons with sinus tarsi pain than in persons without sinus tarsi pain (P<0.001) and TILSA (P=0.032), and CCT (P<0.001) were significantly larger in persons without sinus tarsi pain (Table 1). Of persons with sinus tarsi pain, BME was significantly more frequent in persons with AALTF and TILSA (P=0.032) and CCT were significantly larger in persons with AALTF (Table 2). Conclusion: The MRI findings of patients with sinus tarsi pain showed higher prevalence of AALTF, BME, and STFO. The AALTF may be associated with the MRI findings of talar and calcaneal BME.
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Dodd, W. Alan. "Tars." Dermatologic Clinics 11, no. 1 (1993): 131–35. http://dx.doi.org/10.1016/s0733-8635(18)30289-4.

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Han, Yu, and Yunsi Fei. "TARS." ACM Transactions on Sensor Networks 13, no. 4 (2017): 1–25. http://dx.doi.org/10.1145/3105149.

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Akiyama, Koichi, Yoshinori Takakura, Yasuharu Tomita, Kazuya Sugimoto, Yasuhito Tanaka, and Susumu Tamai. "Neurohistology of the sinus tarsi and sinus tarsi syndrome." Journal of Orthopaedic Science 4, no. 4 (1999): 299–303. http://dx.doi.org/10.1007/s007760050107.

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Beltran, Javier. "SINUS TARSI SYNDROME." Magnetic Resonance Imaging Clinics of North America 2, no. 1 (1994): 59–65. http://dx.doi.org/10.1016/s1064-9689(21)00325-1.

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Dellon, A. Lee, and Stephen L. Barrett. "Sinus Tarsi Denervation." Journal of the American Podiatric Medical Association 95, no. 2 (2005): 108–13. http://dx.doi.org/10.7547/0950108.

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Traumatic neuroma of the branches of the deep peroneal nerve that innervate the sinus tarsi can be the source of recalcitrant lateral ankle pain. That these nerves can be the source of the pain can be demonstrated by nerve blocks, and this pain can be surgically treated by resection of the appropriate branch of the deep peroneal nerve. This article documents the clinical results of this approach in 13 patients with sinus tarsi syndrome. At a minimum of 6 months postoperatively, 10 patients (77%) were completely pain-free, wore normal shoes, and had returned to work. Two patients (15%) had a small degree of residual pain but resumed usual activities and wore normal footwear. One patient had some pain relief but could not resume usual activities. We conclude that denervation of the sinus tarsi can relieve recalcitrant pain emanating from the sinus tarsi. This approach may reduce the need for subtalar fusion or evacuation procedures, including arthroereisis, thus avoiding their potential complications. Moreover, sinus tarsi denervation may allow the continued use of an arthroereisis implant in the presence of satisfactory objective findings, despite the subjective presence of postoperative pain. (J Am Podiatr Med Assoc 95(2): 108–113, 2005)
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Crawford, Michael. "Sinus Tarsi Artery." Journal of Foot and Ankle Surgery 50, no. 6 (2011): 786. http://dx.doi.org/10.1053/j.jfas.2011.09.013.

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Wicart, P., and R. Seringe. "Ostéotomies du tarse." EMC - Techniques chirurgicales - Orthopédie - Traumatologie 5, no. 2 (2010): 1–16. http://dx.doi.org/10.1016/s0246-0467(10)50270-8.

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Wicart, P., and R. Seringe. "Osteotomías del tarso." EMC - Técnicas Quirúrgicas - Ortopedia y Traumatología 2, no. 4 (2010): 1–16. http://dx.doi.org/10.1016/s2211-033x(10)70081-5.

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Piat, Christophe. "Synostoses du tarse." Revue du Rhumatisme Monographies 81, no. 3 (2014): 174–82. http://dx.doi.org/10.1016/j.monrhu.2014.04.003.

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Freeman, Hugh. "Michael Justin Tarsh." Psychiatric Bulletin 18, no. 2 (1994): 119–20. http://dx.doi.org/10.1192/pb.18.2.119-c.

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Frey, Carol, and Neil E. Roberts. "Sinus Tarsi Dysfunction." Sports Medicine and Arthroscopy Review 8, no. 4 (2000): 336–42. http://dx.doi.org/10.1097/00132585-200008040-00004.

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Frey, Carol, and Neil E. Roberts. "Sinus Tarsi Dysfunction." Sports Medicine and Arthroscopy Review 8, no. 4 (2001): 336–42. http://dx.doi.org/10.1097/00132585-200108040-00004.

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Zwipp, H., J. G. Bemmerl, M. Holch, H. Thermann, and H. J. Maschek. "Sinus tarsi and canalis tarsi syndromes. A post-traumatic entity." Foot and Ankle Surgery 2, no. 3 (1996): 181–88. http://dx.doi.org/10.1046/j.1460-9584.1996.00025.x.

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Khongphaophong, Methee. "Sinus tarsi approach vs. extensile lateral approach for intra-articular calcaneal fracture." Foot & Ankle Orthopaedics 3, no. 3 (2018): 2473011418S0028. http://dx.doi.org/10.1177/2473011418s00286.

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Category: Trauma Introduction/Purpose: The options of operative treatment for intra-articular calcaneal fracture still remains controversial. Extensile lateral approach allow excellent exposure to fracture, but bring high rate of wound complications. The aim of this study was to compare the outcome of intra-articular calcaneal fracture treated with open reduction and internal fixation via an extensile lateral versus. Sinus tarsi approach Methods: Prospective study of 62 intra-articular calcaneal fractures treated by open reduction and internal fixation between 2014, October to 2017, June. 29 were treated with extensile lateral approach with calcaneal locking plate(Wright medical, Tennessee), 33 sinus tarsi approach(4 cases need additional mini medial incision approaches for SanderIII AC, BC) with mini-calcaneal locking plate(Normed, Florida). Durations until operation, operative time, foot functional index(total score), visual analog scale, SF-36, Bohler’s angle, angle of Gissane, wound complications and duration of hospital stay were recorded post-operatively and minimal 6 months follow up. Results: Compared 2 groups with demographic datas.Average duration until operation; extensile group was 13.32 days, sinus tarsi group was 6.08 days, p <0.001. Operative time; extensile group was 123.41minutes vs. sinus tarsi group was 91.20 minutes, p <0.001. Wound complications was 24.13% in extensile group vs. 6.06% in sinus tarsi group, p =0.045, Duration of post-operative admission was 6.68 days in extensile group vs. 3.10 days in sinus tarsi group p <0.001 FFI last visits was 25.36 in extensile group vs. 25.65 in sinus tarsi group, p =0.969, VAS activity was 29.68 in extensile group vs. 28.54 in sinus tarsi group, p=0.271. Conclusion: Sinus tarsi approach with mini-calcaneal locking plate was a great option for treatment of intra-articular calcaneal fracture. This approach brought lower rate of wound complications, earlier operations, shorter operation times and shorter hospital stay compared to extensile lateral approach.
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Takagi, Satoshi, and Ryohei Katayama. "Abstract 562: Frequent copy number gain of MCL1 is a therapeutic target for osteosarcoma." Cancer Research 84, no. 6_Supplement (2024): 562. http://dx.doi.org/10.1158/1538-7445.am2024-562.

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Abstract Osteosarcoma (OS) is the most common primary malignant bone tumor that predominantly occurs in children, adolescents, and young adults. The treatment for OS that combines surgery with chemotherapy, which consists of a four-drug combination of adriamycin (DOX), cisplatin (CDDP), high-dose methotrexate (MTX), and ifosfamide, was established in 1970s, and it is still used as a standard therapy. Oncogenic driver mutations and fusion genes common to OS have not been identified, which is one of the reasons for the lack of success in drug development for OS. Herein, to explore the characteristic vulnerability in OS, molecular targeted drugs were screened against OS cell lines and patient-derived cells; obatoclax, a pan-BH3 mimetic, and a concomitant drug that enhances obatoclax-induced apoptosis, OSI906, a dual inhibitor of IGF1R and IR, were found. Fluorescence in situ hybridization (FISH) analysis revealed that copy number gains of MCL1, an antiapoptotic Bcl-2 family protein, were observed in 46.3% of formalin-fixed paraffin-embedded (FFPE) specimens from patients with OS (N = 41) and in 45.5% of OS cell lines (N = 11), thereby causing vulnerability to BH3 mimetics. IHC staining also revealed high expression of Mcl-1 protein in specimens with MCL1-amplification in FISH analysis. Pharmacological or genetic inhibition of Mcl-1 induced potent apoptosis in MCL1-amplified OS cells, which was enhanced by the co-inhibition with Bcl-xL. Moreover, chromosome 1q21.2-3, where MCL1 is located, contains several IGF1R/PI3K pathway-related genes, including PIP5K1A, TARS2, OUTD7B, and ENSA, whose copy numbers were also increased in MCL1-amplified OS cells, suggesting that 1q21.2-3-amplified OS cells readily activate downstream pathways via IGF1R. IGF signaling activation in 1q21.2-3-amplified OS cells negated the obatoclax-induced apoptosis, which was overcome by OSI906 treatment. Combined obatoclax and OSI906 administration remarkably suppressed MCL1-amplified OS tumor growth in the xenograft mouse model and resulted in tumor regression; however, none of the treatments reduced tumor growth of OS without MCL1 amplification. These results suggest that combining obatoclax with OSI906 could be a potential therapeutic intervention for 1q21.2-3-amplified OS, and that prior stratification of OS based on the 1q21.2-3 amplification status would be important for the success of this combination therapy. Thus, we elucidated the mechanism of action of drugs and their potential as a novel therapeutic strategy for approximately 50% of patients with OS. Moreover, a FISH analysis that can detect copy number gains of MCL1 in FFPE specimens from patients with OS was established to stratify patients eligible for this therapy. Citation Format: Satoshi Takagi, Ryohei Katayama. Frequent copy number gain of MCL1 is a therapeutic target for osteosarcoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 562.
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Willegger, Madeleine, Maryse Bouchard, Gilbert M. Schwarz, Lena Hirtler, and Andrea Veljkovic. "The Evolution of Sinus Tarsi Syndrome—What Is the Underlying Pathology?—A Critical Review." Journal of Clinical Medicine 12, no. 21 (2023): 6878. http://dx.doi.org/10.3390/jcm12216878.

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Background and Objectives: Sinus tarsi syndrome (STS) is defined as pain located at the lateral opening of the tarsal sinus. The exact etiology of sinus tarsi syndrome is not completely understood. Some do not believe it to be a true pathology. This review aims to clarify the definition of sinus tarsi syndrome to better understand the underlying pathologies. We further propose an algorithm to evaluate sinus tarsi pain and provide advice for consecutive treatment options. Design: This is a narrative review. By searching PubMed, the available current literature was reviewed. Articles were critically analyzed to determine the pathoanatomy, biomechanics, and etiology of sinus tarsi pain. Algorithms for clinical evaluation, diagnosis, and treatment were also recorded. Finally, the authors approach to evaluating and treating sinus tarsi pain was included in this review. Results: Reviewing the available literature, STS seems to be a catch-all phrase used to describe any pain in this anatomic region. Many causes of sinus tarsi pain were listed, including impingement, subtalar instability, and many other pathologies around the ankle. Conclusions: A thorough evaluation of patients presenting with pain in the sinus tarsi or instability of the hindfoot is essential to determining the underlying cause. When the cause of pain is still not clear after clinical exam and radiologic assessment, subtalar arthroscopy can be helpful as both a diagnostic and treatment tool. We propose that the term of STS should be avoided and that a more accurate diagnosis be used when possible. Once a diagnosis is made, appropriate treatment can be initiated.
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Wang, Wei, Jianguo Qian, and Toshiki Abe. "Alon–Tarsi Number and Modulo Alon–Tarsi Number of Signed Graphs." Graphs and Combinatorics 35, no. 5 (2019): 1051–64. http://dx.doi.org/10.1007/s00373-019-02056-9.

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Schwarzenbach, B., C. Dora, A. Lang, and R. O. Kissling. "Blood vessels of the sinus tarsi and the sinus tarsi syndrome." Clinical Anatomy 10, no. 3 (1997): 173–82. http://dx.doi.org/10.1002/(sici)1098-2353(1997)10:3<173::aid-ca3>3.0.co;2-v.

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Zhu, Xiangjiu, Hongxing Jiang, Yukai Zhang, et al. "Tunable Contact Types and Interfacial Electronic Properties in TaS2/MoS2 and TaS2/WSe2 Heterostructures." Molecules 28, no. 14 (2023): 5607. http://dx.doi.org/10.3390/molecules28145607.

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Following the successful experimental synthesis of single-layer metallic 1T-TaS2 and semiconducting 2H-MoS2, 2H-WSe2, we perform a first-principles study to investigate the electronic and interfacial features of metal/semiconductor 1T-TaS2/2H-MoS2 and 1T-TaS2/2H-WSe2 van der Waals heterostructures (vdWHs) contact. We show that 1T-TaS2/2H-MoS2 and 1T-TaS2/2H-WSe2 form n-type Schottky contact (n-ShC type) and p-type Schottky contact (p-ShC type) with ultralow Schottky barrier height (SBH), respectively. This indicates that 1T-TaS2 can be considered as an effective metal contact with high charge injection efficiency for 2H-MoS2, 2H-WSe2 semiconductors. In addition, the electronic structure and interfacial properties of 1T-TaS2/2H-MoS2 and 1T-TaS2/2H-WSe2 van der Waals heterostructures can be transformed from n-type to p-type Schottky contact through the effect of layer spacing and the electric field. At the same time, the transition from Schottky contact to Ohmic contact can also occur by relying on the electric field and different interlayer spacing. Our results may provide a new approach for photoelectric application design based on metal/semiconductor 1T-TaS2/2H-MoS2 and 1T-TaS2/2H-WSe2 van der Waals heterostructures.
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Hummel, Hans-Ulrich, Richard Fackler та Peter Remmert. "Zur Kenntnis neuer supraleitender Einlagerungsverbindungen von organischen Fünfring-Heterocyclen in 2H-Tantaldisulfid / New Superconducting Intercalation Compounds of Organic Five-Membered Heterocyclic Compounds with 2 Η-Tantalum Disulfide". Zeitschrift für Naturforschung B 47, № 5 (1992): 741–47. http://dx.doi.org/10.1515/znb-1992-0522.

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The intercalation compounds TaS2(pyrrole)0.5 (1), TaS2(2-methylpyrrole)0.33 (2), TaS2(2,5-dimethylpyrrole) (3), TaS2(thiazole)0.33 (4) and TaS2(imidazole)0.33 (5) are formed readily in closed systems at temperatures up to 200°C. Furane and thiophene show no tendency to intercalate in 2H–TaS2. Compounds 2-5 are molecular intercalation species, and deintercalation is finished at 350°C, while in 1 the pyrrole guests have been associated and thermally induced deintercalation proceeds up to 900°C with fragmentation. 1-5 can be indexed on the basis of hexagonal symmetry assuming the space group P63/mmc. In 1 the stacking sequence of the host lattice TaS2 remains unchanged while in 2, 3 and 5 a transformation from the BaB CaC stacking of 2H –TaS2 to a sequence AbA AcA occurs. In 4 a stacking CbC BcB like in MoS2 is realized. 1-5 show superconducting behaviour at low temperatures, 2 exhibits a pronounced metall-semiconductor transition at 220 K.
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Jung, Hong-Geun, Jong-won Lee, and Won Tae Song. "The Interosseous Talocalcaneal Ligament Injury Findings in Lateral Ankle Instability with Sinus Tarsi Pain." Foot & Ankle Orthopaedics 4, no. 4 (2019): 2473011419S0003. http://dx.doi.org/10.1177/2473011419s00039.

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Category: Ankle, Arthroscopy, Sports Introduction/Purpose: Lateral ankle instability (LAI) with concomitant sinus tarsi pain is a quite common finding. However, there has been few studies evaluating the subtalar arthroscopic findings for LAI with sinus tarsi pain. The purpose of the study is to evaluate the ST arthroscopic findings of chronic ankle instability with sinus tarsi syndrome. We hypothesized that chronic ankle instability with sinus tarsi pain is highly associated with interosseous talocalcaneal ligament (ITCL) tear which may be the cause for subtalar instability (STI). Methods: The study is based on 104 LAI with sinus tarsi pain ankles who had performed lateral ankle ligament stabilization. i.e. Modified Brostrum procedure (MBP), lateral ankle reconstruction (LAR) or subtalar ligament reconstruction (STR) with subtalar arthroscopic (STA) examinations from 2007 to 2018. The STA has been mainly focused on the ITCL injury and debridement of the ITCL tears and synovitis were performed when present. VAS pain score, AOFAS, Karlsson-Peterson functional score were evaluated. Results: According to the ST arthrosopic findings, ITCL tears were present in 94% (98/104) of the ankles. Lateral ankle instability (LAI), subtalar instability (STI), and LAI and STI combined were 32%, 30% and 38% respectively. MBP, LAR and STR were performed in 23%, 22% and 56% respectively. VAS pain score was improved from 5.3 to 1.9 (p&lt;0.05). AOFAS score was improved from 67 to 89 (p&lt;0.05), while K-P score improved from 50 to 83 (p&lt;0.05). Sinus tarsi pain was relieved in 65% of the patients. Conclusion: We found the high incidence of the ITCL tears (98%) in LAI with sinus tarsi pain, and also diagnosed the STI in 68% of the ankles. We believe that in case of LAI with sinus tarsi pain, ST arthroscopic evaluation for ITCL tears is necessary and the possibility
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Baumfeld, Daniel, Thiago A. Silva, Shuyuan Li, et al. "Is Lateral Impingement a Good Predictor of Peritalar Subluxation in Patients with Adult Acquired Flatfoot Deformity?" Foot & Ankle Orthopaedics 5, no. 4 (2020): 2473011420S0002. http://dx.doi.org/10.1177/2473011420s00021.

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Category: Ankle Arthritis; Ankle; Hindfoot; Other Introduction/Purpose: Sinus tarsi and Subfibular impingement are considered the main causes of lateral foot pain in patients with Adult Acquired Flatfoot Deformity (AAFD). They are considered important markers in the spectrum of progressive peritalar subluxation (PTS) in patients with AAFD. Recent literature has also highlighted the use of the Middle Facet of the subtalar joint as a more accurate indicator of PTS. The objective of this study was to assess the relationship between lateral impingement and middle facet PTS. Our hypotheses were that patients with sinus tarsi and subfibular impingement would demonstrate more severe PTS than patients with no impingement, and that subfibular impingement would represent a better indicator of pronounced deformity when compared to sinus tarsi impingement. Methods: In this retrospective comparative Cohort Study, we included 110 AAFD patients that underwent standing weightbearing CT (WBCT) as a standard baseline assessment of their foot deformity. The presence or absence of sinus tarsi and subfibular impingements, as well as the incongruence angle and percentage of subluxation of the middle facet of the subtalar joint, were manually measured on multiplanar reconstruction (MPR) WBCT images by a blinded fellowship-trained foot and ankle surgeon. Descriptive statistics were used to describe the rate of sinus tarsi and subfibular impingement as well as mean values for middle facet incongruence angle and subluxation. Wilcoxon test was used to compare the values of PTS at the middle facet in patients with or without sins tarsi and subfibular impingement. A partition prediction model was used to assess the values of middle facet PTS that would foresee a higher risk for lateral impingement. P-values &lt;0.05 were considered significant. Results: Seventy-five percent (n=82) of the AAFD patients had sinus tarsi impingement and 64% (n=70) of the AAFD patients had subfibular impingement. The mean value and 95% CI for middle facet incongruence angle and subluxation percentage were respectively 10.5o (CI, 8.7 to 12.2o) and 28.7% (CI, 23.5 to 33.9%). Middle facet subluxation was significantly higher in patients with sinus tarsi and subfibular impingement by respectively 22.6% and 23.9%, both p-values &lt;0.0001. No similar significant differences were observed on incongruence angle measurements. The partition model demonstrated that the middle facet subluxation percentage was the best predictor of both sinus tarsi (R2=0.15) and subfibular impingements (R2=0.17), with 24.9% subluxation representing an important threshold for higher risk of sinus tarsi (90% incidence) and subfibular impingements (84% incidence). Conclusion: Our results showed significantly increased middle facet subluxation in AAFD patients with sinus tarsi and subfibular impingement. Subfibular impingement was less frequent and associated with more pronounced deformity than sinus tarsi impingement. Measurements of the percentage of subluxation of the middle facet were also found to be the best predictor of impingement, with 29.4% representing an important threshold value above which the risks for both sinus tarsi and subfibular impingement were significantly higher. With that in mind, we would recommend close assessment and follow-up of the amount of middle facet subluxation in the decision-making for the treatment of AAFD patients.
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31

De Hollanda, Cristina Buarque. "Entrevista com Tarso Genro." Revista Estudos Políticos 10, no. 20 (2020): 179. http://dx.doi.org/10.22409/rep.v10i20.43388.

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Tarso Genro Advogado e professor universitário. Foi deputado federal (1989, 1990-1991), duas vezes prefeito de Porto Alegre (1993-1996; 2001-2002), foi Ministro da Educação (2004-2005) e Ministro das Relações Institucionais (2006-2007) do primeiro governo Lula. Depois, Ministro da Justiça (2007-2010) no segundo mandato do mesmo Presidente e governador do Rio Grande do Sul (2011-2015).
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32

Klausner, Victor B., and Mark E. McKeigue. "The Sinus Tarsi Syndrome." Physician and Sportsmedicine 28, no. 5 (2000): 75–80. http://dx.doi.org/10.3810/psm.2000.05.900.

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Mauerer, A., and R. Forst. "Das Sinus-tarsi-Syndrom." Zeitschrift für Orthopädie und Unfallchirurgie 145, no. 06 (2007): 801–12. http://dx.doi.org/10.1055/s-2007-989283.

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34

Minguella, J., L. Terricabras, and M. Cabrera. "Sinóstosis congénita del tarso." Revista de Ortopedia y Traumatología 49, no. 2 (2005): 121–25. http://dx.doi.org/10.1016/s0482-5985(05)74397-2.

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Minguella, J., L. Terricabras, and M. Cabrera. "Sinóstosis congénita del tarso." Revista Española de Cirugía Ortopédica y Traumatología 49, no. 2 (2005): 121–25. http://dx.doi.org/10.1016/s1888-4415(05)76286-x.

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Herrmann, M., and K. S. Pieper. "Das Sinus-tarsi-Syndrom." Der Unfallchirurg 111, no. 2 (2008): 132–36. http://dx.doi.org/10.1007/s00113-007-1387-3.

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Lehnert, Matthew S. "Big Tarsi To Fill." American Entomologist 69, no. 1 (2023): 3. http://dx.doi.org/10.1093/ae/tmad008.

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Romano, Leandro, Alexandre Schmaedecke, Laura Bertolacini Romano, and Cássio Ricardo Auada Ferrigno. "Luxação tarsometatársica em cão: artrodese parcial utilizando placa em "t" - relato de caso." Revista de Educação Continuada em Medicina Veterinária e Zootecnia do CRMV-SP 8, no. 1 (2005): 48–54. http://dx.doi.org/10.36440/recmvz.v8i1.3177.

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Objetivo: Apresentar caso de artrodese parcial com utilização de placa óssea em "t" e parafusos como tratamento de luxação de tarso em cão. Descrição: Cadela sem raça definida, três anos de idade, aproximadamente 14 kg, foi atendida no Serviço de Cirurgia Ortopédica da Faculdade de Medicina Veterinária da Universidade de São Paulo (FMVZ/ USP), São Paulo, SP, com histórico de claudicação. Ao exame físico, o animal apresentava impotência funcional de membro posterior esquerdo, aumento de volume e sensibilidade dolorosa. À palpação do membro notou-se mobilidade anormal, crepitação presente, dor severa e instabilidade na região da articulação tarso metatársica. O exame radiográfico revelou luxação tarso metatársico com desvio do eixo axial e perda parcial da relação articular tarso metatársico. Com base nos sinais clínicos, radiográficos e laboratoriais, marcou-se a cirurgia. A placa em "t" foi posicionada de maneira que os dois parafusos proximais ficassem fixados no tarso e os quatro parafusos distais no terceiro metatarsiano. No pós-operatório imediato foi adotado penso esparadrapo com talas laterais por 60 dias. Em dois meses de pós-operatório foi dado alta ao paciente. Conclusões: A artrodese total é atualmente o procedimento cirúrgico mais utilizado em luxações do tarso de cães. Porém, a artrodese parcial pode ser considerada por apresentar pouca complicação e pequeno risco de falha do implante, com preservação da integridade de articulações não afetadas.
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Masrom, S., N. Khairuddin, A. Abdul Rahman, A. Azizan, and A. S.A. Rahman. "An Evaluation Framework of Trust Aware Recommender System." International Journal of Engineering & Technology 7, no. 4.33 (2018): 5. http://dx.doi.org/10.14419/ijet.v7i4.33.23472.

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To date, there exists a variety of prediction approaches have been used in recommender systems. Among the widely known approaches are Content Based Filtering (CBF) and Collaborative Filtering (CF). Based on literatures, CF with users rating element has been widely used but the approach faced two common problems namely cold start and sparsity. As an alternative, Trust Aware Recommender Systems (TARS) for the CF based users rating has been introduced. The research progress on TARS improvement is found to be rapidly progressing but lacking in the algorithm evaluation has been started to appear. Many researchers that introduced their new TARS approach provides different evaluation of users’ views for the TARS performances. As a result, the performances of different TARS from different publications are not comparable and difficult to be analyzed. Therefore, this paper is written with objective to provide common group of the users’ views based on trusted users in TARS. Then, this paper demonstrates a comparison study between different TARS techniques with the identified common groups by means of the accuracy error, rating and users coverage. The results therefore provide a relative comparison between different TARS.
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Cain, Jeffrey D., Sehoon Oh, Amin Azizi, et al. "Ultranarrow TaS2 Nanoribbons." Nano Letters 21, no. 7 (2021): 3211–17. http://dx.doi.org/10.1021/acs.nanolett.1c00481.

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Silverman, Alan, Alan Menter, and Janda L. Hairston. "Tars and Anthralins." Dermatologic Clinics 13, no. 4 (1995): 817–33. http://dx.doi.org/10.1016/s0733-8635(18)30045-7.

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Porch, Timothy G., James R. Smith, James S. Beaver, Phillip D. Griffiths, and Craig H. Canaday. "TARS-HT1 and TARS-HT2 Heat-tolerant Dry Bean Germplasm." HortScience 45, no. 8 (2010): 1278–80. http://dx.doi.org/10.21273/hortsci.45.8.1278.

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43

Mamedov, T., and A. Yusif-zade. "SEPARATION OF TARS AND ASPHALTENES FROM TARS OF AZERBAIJAN OILS." Scientific heritage, no. 101 (November 21, 2022): 15–17. https://doi.org/10.5281/zenodo.7340719.

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This research is devoted to studying the elemental composition and yield of asphaltene and resin fractions from Azerbaijan oils processed at the Heydar Aliyev Baku Oil Refinery. Acetone was proposed as a solvent, IR spectra for resins and asphaltenes were taken, and the structural group composition was given according to IR spectra. Asphaltene molecules contain polycyclic rings with aromatic cycles and S, O, N heteroatoms and metals. We have shown that the settled asphaltenes were divided into two fractions, which differ in elemental composition and IR spectroscopy.
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Goenaga, Ricardo, Mark Guiltinan, Siela Maximova, Ed Seguine, and Heber Irizarry. "Yield Performance and Bean Quality Traits of Cacao Propagated by Grafting and Somatic Embryo-derived Cuttings." HortScience 50, no. 3 (2015): 358–62. http://dx.doi.org/10.21273/hortsci.50.3.358.

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Twelve cacao (Theobroma cacao) clones propagated by grafting and orthotropic rooted cuttings of somatic embryo-derived plants were grown on an Ultisol soil at Corozal, Puerto Rico, and evaluated for 6 years of production under intensive management. Year, variety, year × variety, and propagation treatment × variety interactions indicated significant effects for dry bean yield, number of pods produced, pod index, plant height, and stem diameter. Propagation treatments had a significant effect on dry bean yield and pod index but not on number of pods produced. Average yield across varieties for both propagation treatments was 2087.9 kg·ha−1 per year of dry beans. There was a highly significant variety effect. ‘UF-668’ was the top yielder averaging 2536.7 kg·ha−1 per year of dry beans; however, this yield was not significantly different from the average yield of varieties ‘TARS-30’, ‘TARS-1’, ‘TARS-13’, ‘TARS-14’, and ‘TARS-2’, which averaged 2427.0 kg·ha−1 per year. Except for ‘UF-668’, the TARS varieties were released in 2009 as high-yielding selections. Propagation treatments had a significant effect on dry bean yield. Dry bean yield of varieties propagated by grafting was 7% higher (2166.7 kg·ha−1 per year) than those propagated by orthotropic rooted cuttings of somatic embryo-derived plants (2009.2 kg·ha−1 per year). This yield difference could not be attributed to grafted plants being more vigorous nor by differences in root architecture. The lowest pod index value in both propagation treatments was obtained by ‘UF-668’; however, pod index for this variety did not differ significantly from values for ‘TARS-2’ and ‘TARS-23’ in grafted plants and from ‘TARS-2’, ‘TARS-23’, and ‘TARS-1’ in plants propagated by orthotropic rooted cuttings of somatic embryo-derived plants. With few exceptions, flavor characteristics were not significantly affected by propagation treatments. Although there were significant differences between plant propagation treatments for some of the variables measured in this study, these were not of a magnitude that would preclude the use of somatic embryogenesis as a viable propagation system for cacao.
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Hull, Michael, Tyler Rutherford, Clifford Jeng, John T. Campbell, and Rebecca Cerrato. "Sinus Tarsi Volume Changes with Hindfoot Position on Weight-Bearing CT Scan." Foot & Ankle Orthopaedics 2, no. 3 (2017): 2473011417S0002. http://dx.doi.org/10.1177/2473011417s000207.

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Category: Basic Sciences/Biologics, Hindfoot Introduction/Purpose: Sinus Tarsi syndrome is a frequent cause of anterolateral foot pain following injury. Chronic lateral subtalar pain, often referred to as “Sinus Tarsi Syndrome”, is commonly reported to occur following trauma. One hypothetical epidemiological predisposing factor for sinus tarsi syndrome is flatfoot deformity with valgus hind foot alignment. Common conservative treatment includes medial heel posting to attempt to widen the sinus tarsi space and alleviate synovitic pain. Although treatment with operative intervention has been reported, no data exists to evaluate if hindfoot realignment functionally opens the sinus tarsi volume. Methods: Weight-bearing Computed Tomography (CT) scans were obtained in 5 healthy volunteers standing at rest on slanted platforms, 25 degree valgus and 25 degree varus. The volume of the sinus tarsi was measured on each scan. Cross sectional area of the sinus tarsi was measured in 3.6 mm slices from the most lateral fully enclosed image to the most lateral aspect of the middle facet of the subtalar joint. Area measurements were multiplied by cut depth (3.6 mm) and summed. Critical angle distance was measured as a straight line from the most lateral point of the lateral process of the talus to the base of the critical angle of Gissane. Subfibular distance was then measured from the most distal tip of the fibula in a straight line to the nearest point of the lateral calcaneal wall. Data were compared using a one way ANOVA and Tukey’s multiple comparison test. Results: The mean sinus tarsi volume in the valgus position was 325.1 mm3 (±88) and 313.3 (±71) for the left and right foot, respectively. In the varus position, the mean sinus tarsi volume increased to 646.8 mm3 (±169) and 599 mm3 (±203). There was a significant difference between the varus and valgus position for both feet (left p&lt;0.01 / right p&lt;0.05). The critical angle distance increased from 28.1 mm (±7.5) to 91.3 mm (±26) for the left foot and 26.3 mm (±7.6) to 87 mm (±27.9) for the right foot when realigned to the varus position (p&lt;0.0001). There was not a significant increase in the sub fibular distance when repositioned from valgus to varus (p=0.06 / p=0.35). Conclusion: This study confirms that moving from a valgus to a varus position significantly increases the volume of the sinus tarsi as well as significantly increases the distance from the lateral process of the talus to the calcaneal angle of Gissane. Interestingly, subfibular distance did not significantly increase, although this may reach significance with increased samples. With confirmation that adjusting hindfoot positioning impacts lateral osseous impingement, future studies are warranted to correlate these findings with clinical symptoms.
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Gehm, Marcelo V., Claudia A. Duarte, Carla T. Leite, et al. "Arthrographic Study of the Communication between the Tarsal Joints in Crioulo Horses." Veterinary and Comparative Orthopaedics and Traumatology 32, no. 04 (2019): 269–73. http://dx.doi.org/10.1055/s-0039-1688770.

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Abstract Objective The aim of the present study is to assess an arthrographic technique based on the access to the equine tarsus via distal intertarsal and on the existence and frequency of communication between distal and tarsocrural joints in the tarsus of Crioulo horses. Materials and Methods Fifty Crioulo horses of both sexes from 3 to 8 years old were included in the experiment. Animals with radiographic signs of tarsal osteoarthritis and joint space loss were excluded from the experiment. Contrast was injected in the distal intertarsal joint and radiographs were taken at two different times - Time 0 (after contrast application) and Time 1 (45 seconds after) to detect any communication between tarsal joints. The recorded results were analysed through chi-squared test. Results Thirty out of three hundred tarsi were excluded from the experiment since the radiographic images showed loss of the distal intertarsal joint space. Positive contrast was injected in distal intertarsal joint of 70/100 tarsi. There was not any contrast overflow in the 30/70 assessed tarsi. Contrast diffused to the tarsometatarsal joint in 32/70 of the assessed tarsi and reached tarsocrural joints in 8/70 tarsi. The adopted arthrographic technique was effective in data collection and evaluation; however, 52/70 of tarsi showed contrast overflow to the bursa of the cunean tendon. Clinical significance The communication between tarsocrural and distal tarsal joints in Crioulo horses was significantly higher, and this finding emphasizes the importance of performing contrasted arthrography before getting to a final diagnostic and defining therapeutic procedures.
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47

Giorgini, RJ, and RL Bernard. "Sinus tarsi syndrome in a patient with talipes equinovarus." Journal of the American Podiatric Medical Association 80, no. 4 (1990): 218–22. http://dx.doi.org/10.7547/87507315-80-4-218.

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The literature reports that 70% of the cases of sinus tarsi syndrome are post-traumatic, following an inversion sprain, and that 30% result from inflammatory disorders, such as rheumatoid arthritis, ankylosing spondylitis, and gouty arthritis. However, in the case presented, talipes equinovarus deformity and sinus tarsi syndrome coexisted. One of the corrective goals in the management of the talipes equinovarus deformity is the realignment of the articulation between the medial plantarly deviated talar head and the anteromedial segment of the calcaneus. The calcaneus must be rotated from a plantarflexed position into a dorsiflexed position. The posterior tubercle will be moved down and in, with the anterior process moved up and out away from the talar head. By correcting the plantarflexed varus attitude of the calcaneus, it is put in a valgus position that often closes down the sinus tarsi upon weightbearing. This compression may result in pain over the lateral aspect of the midfoot with hindfoot instability, as seen in the case presented. As a result of the abnormal anatomical relationship of the talus and calcaneus, the patient developed severe pain in the sinus tarsi. Based on the medical history and present postoperative results, the authors find a long-term sequela of talipes equinovarus deformity to be sinus tarsi syndrome.
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Mauterer, John V., Raymond G. Prata, Carol A. Carberry, and Steven C. Schrader. "Displacement of the tendon of the superficial digital flexor muscle in dogs: 10 cases (1983–1991)." Journal of the American Veterinary Medical Association 203, no. 8 (1993): 1162–65. http://dx.doi.org/10.2460/javma.1993.203.08.1162.

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Summary Displacement of the tendon of the superficial digital flexor muscle was diagnosed in 9 dogs (10 tarsi). Four of 10 displacements occurred in Shetland Sheepdogs. All dogs had an acute onset of lameness with swelling over the proximal end of the tuber cal-canei. Lateral displacement occurred in 8 tarsi and medial displacement in 2 tarsi. Nonsurgical treatment (exercise restriction, bandaging, and administration of anti-inflammatory medication) was ineffective in the 5 dogs in which it was attempted. Surgical reconstruction of the supporting soft tissues resulted in return to normal function in 9 cases available for follow-up evaluation.
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Udawatta, Thiran, Lawrence H. Goodnough, and Stephen K. Benirschke. "Lateral Extensile Approach to the Calcaneus is Safe after Sinus Tarsi Incision: A Report of Two Cases." Foot & Ankle Orthopaedics 7, no. 1 (2022): 2473011421S0047. http://dx.doi.org/10.1177/2473011421s00473.

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Category: Trauma; Hindfoot Introduction/Purpose: While the optimal surgical approach for operative treatment of calcaneus fractures is controversial. Regardless of index approach, post-injury sequelae such as malunion may require subsequent extensile exposures for reconstruction. In the tenuous soft tissues overlying the Whether a lateral extensile approach is safe following a previous sinus tarsi exposure has yet to be demonstrated. Methods: In this case report, two individuals underwent an initial sinus tarsi approach for reduction and fixation of calcaneus fractures, but went on to malunion or subtalar arthritis. A 'sham' surgery consisting of skin incision and initial flap elevation was performed to evaluate the efficacy of a lateral extensile approach to the calcaneus after previous sinus tarsi incision. Results: In each instance, the patients experienced uneventful skin incision healing, and subsequently had successful reconstruction with distraction subtalar arthrodesis via lateral extensile exposures. Conclusion: The lateral extensile approach to the calcaneus may be safely performed following sinus tarsi exposure.
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Seok, Hyunho, Inkoo Lee, Jinill Cho, et al. "Synthesis of vertically aligned wafer-scale tantalum disulfide using high-Ar/H2S ratio plasma." Nanotechnology 33, no. 2 (2021): 025603. http://dx.doi.org/10.1088/1361-6528/ac2b6c.

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Abstract Nanostructural modification of two-dimensional (2D) materials has attracted significant attention for enhancing hydrogen evolution reaction (HER) activity. In this study, the nanostructure of TaS2 films was controlled by controlling the Ar/H2S gas ratio used in plasma-enhanced chemical vapor deposition (PECVD). At a high Ar/H2S gas ratio, vertically aligned TaS2 (V-TaS2) films were formed over a large-area (4 in) at a temperature of 250 °C, which, to the best of our knowledge, is the lowest temperature reported for PECVD. Furthermore, the plasma species formed in the injected gas at various Ar/H2S gas ratios were analyzed using optical emission spectroscopy to determine the synthesis mechanism. In addition, the 4 in wafer-scale V-TaS2 was analyzed by x-ray photoelectron spectroscopy, transmission electron microscopy, and atomic force microscopy, and the HER performance of the as-synthesized TaS2 fabricated with various Ar/H2S ratios was measured. The results revealed that, depending on the film structure of TaS2, the HER performance can be enhanced owing to its structural advantage. Furthermore, the excellent stability and robustness of V-TaS2 was confirmed by conducting 1000 HER cycles and post-HER material characterization. This study provides important insights into the plasma-assisted nanostructural modification of 2D materials for application as enhanced electrocatalysts.
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